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  1. Content type: Research article

    Understanding the underlying molecular mechanisms involved in the formation of cutaneous malignant melanoma is critical for improved diagnosis and treatment. Keratinocytic nuclear receptor Retinoid X Receptor ...

    Authors: Sharmeen Chagani, Rong Wang, Evan L. Carpenter, Christiane V. Löhr, Gitali Ganguli-Indra and Arup K. Indra

    Citation: BMC Cancer 2017 17:736

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  2. Content type: Research article

    Liver resection had been regarded as a standard treatment for primary hepatocellular carcinoma (HCC). However, early mortality and recurrence after surgery were still of major concern. RAM (Risk Assessment for...

    Authors: Heng-Yuan Hsu, Ming-Chin Yu, Chao-Wei Lee, Hsin-I Tsai, Chang-Mu Sung, Chun-Wei Chen, Shu-Wei Huang, Cheng-Yu Lin, Wen-Juei Jeng, Wei-Chen Lee and Miin-Fu Chen

    Citation: BMC Cancer 2017 17:742

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  3. Content type: Research article

    Data is needed about barriers to self-collection of Human Papillomavirus (HPV) samples and cytology among low-income, disadvantaged women living in rural areas of lower-income countries as these women are at i...

    Authors: Betania Allen-Leigh, Patricia Uribe-Zúñiga, Leith León-Maldonado, Brandon J. Brown, Attila Lörincz, Jorge Salmeron and Eduardo Lazcano-Ponce

    Citation: BMC Cancer 2017 17:734

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  4. Content type: Research article

    Circulating cell-free miRNAs have emerged as promising minimally-invasive biomarkers for early detection, prognosis and monitoring of cancer. They can exist in the bloodstream incorporated into extracellular v...

    Authors: Edgars Endzeliņš, Andreas Berger, Vita Melne, Cristina Bajo-Santos, Kristīne Soboļevska, Artūrs Ābols, Marta Rodriguez, Daiga Šantare, Anastasija Rudņickiha, Vilnis Lietuvietis, Alicia Llorente and Aija Linē

    Citation: BMC Cancer 2017 17:730

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  5. Content type: Research article

    Colorectal cancer (CRC) is a major global public health problem and the second leading cause of cancer-related death. Mitochondrial dysfunction has long been suspected to be involved in this type of tumorigene...

    Authors: Jéssica Alonso-Molero, Carmen González-Donquiles, Tania Fernández-Villa, Fernanda de Souza-Teixeira, Laura Vilorio-Marqués, Antonio J. Molina and Vicente Martín

    Citation: BMC Cancer 2017 17:731

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  6. Content type: Research article

    There are three main therapeutic strategies, namely expectant management (dilation and curettage only), prophylactic chemotherapy and prophylactic total hysterectomy for treating older women with complete hyda...

    Authors: Peng Zhao, Qinqing Chen and Weiguo Lu

    Citation: BMC Cancer 2017 17:733

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  7. Content type: Case report

    Pregnancy is an unquantifiable risk to accelerate tumor growth of papillary thyroid carcinoma (PTC), and whether pregnancy induces an unfavorable prognosis of radioiodine refractory papillary thyroid carcinoma...

    Authors: Yuchen Jin, Min Liu, Lingxiao Cheng and Libo Chen

    Citation: BMC Cancer 2017 17:735

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  8. Content type: Research article

    The diagnostic and prognostic significance of carcinoembryonic antigen (CEA), carbohydrate associated antigen 19–9 (CA19–9), alpha-fetoprotein (AFP) and cancer antigen 125 (CA125) in early gastric cancer have ...

    Authors: Fan Feng, Yangzi Tian, Guanghui Xu, Zhen Liu, Shushang Liu, Gaozan Zheng, Man Guo, Xiao Lian, Daiming Fan and Hongwei Zhang

    Citation: BMC Cancer 2017 17:737

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  9. Content type: Research article

    Patients suffering from advanced stage hepatocellular carcinoma (HCC) often exhibit a poor prognosis or dismal clinical outcomes due to ineffective chemotherapy or a multi-drug resistance (MDR) process. Thus, ...

    Authors: Jun Hou, Zhixian Hong, Fan Feng, Yantao Chai, Yunkai Zhang, Qiyu Jiang, Yan Hu, Shunquan Wu, Yingsong Wu, Xunian Gao, Qiong Chen, Yong Wan, Jingfeng Bi and Zheng Zhang

    Citation: BMC Cancer 2017 17:729

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  10. Content type: Research article

    The aim of this study was to identify miRNAs specifically dysregulated in BRAF-mutated colorectal cancer, which could lead to a better understanding of the molecular mechanisms underlying oncogenesis of this mali...

    Authors: Hidekazu Takahashi, Masanobu Takahashi, Shinobu Ohnuma, Michiaki Unno, Yuki Yoshino, Kota Ouchi, Shin Takahashi, Yasuhide Yamada, Hideki Shimodaira and Chikashi Ishioka

    Citation: BMC Cancer 2017 17:723

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  11. Content type: Research article

    Epithelial-mesenchymal transition (EMT) is an early event in tumour invasion and metastasis, and widespread and distant metastasis at early stages is the typical biological behaviour in small cell lung cancer ...

    Authors: Tingting Wang, Xufang Chen, Weiwei Qiao, Lijun Kong, Daqing Sun and Zunling Li

    Citation: BMC Cancer 2017 17:719

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  12. Content type: Research article

    Triple-negative breast cancer (TNBC) is characterized by a lack of estrogen and progesterone receptor expression (ESR and PGR, respectively) and an absence of human epithelial growth factor receptor (ERBB2) ampli...

    Authors: Melissa Quintero, Douglas Adamoski, Larissa Menezes dos Reis, Carolline Fernanda Rodrigues Ascenção, Krishina Ratna Sousa de Oliveira, Kaliandra de Almeida Gonçalves, Marília Meira Dias, Marcelo Falsarella Carazzolle and Sandra Martha Gomes Dias

    Citation: BMC Cancer 2017 17:727

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  13. Content type: Research article

    Circulating tumor cells (CTCs) have been accepted as a prognostic marker in patients with metastatic colorectal cancer (mCRC, UICC stage IV). However, the prognostic value of CTCs in patients with non-metastat...

    Authors: Chaogang Yang, Kun Zou, Liang Zheng and Bin Xiong

    Citation: BMC Cancer 2017 17:725

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  14. Content type: Research article

    MicroRNAs may act as oncogenes or tumour suppressor genes, which make these small molecules potential diagnostic/prognostic factors and targets for anticancer therapies. Several common oncogenic microRNAs have...

    Authors: Malgorzata Bulkowska, Agata Rybicka, Kerem Mert Senses, Katarzyna Ulewicz, Katarzyna Witt, Joanna Szymanska, Bartlomiej Taciak, Robert Klopfleisch, Eva Hellmén, Izabella Dolka, Ali O. Gure, Joanna Mucha, Mariusz Mikow, Slawomir Gizinski and Magdalena Krol

    Citation: BMC Cancer 2017 17:728

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  15. Content type: Case report

    Trastuzumab-related cardiotoxicity has been reported in patients receiving trastuzumab concurrently with other agents, especially with anthracyclines. Cardiac function damage is generally rare, precox and mild...

    Authors: Santino Minichillo, Ilaria Gallelli, Elena Barbieri, Marta Cubelli, Daniela Rubino, Sara Quercia, Massimo Dall’Olio, Claudio Rapezzi and Claudio Zamagni

    Citation: BMC Cancer 2017 17:722

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  16. Content type: Research article

    To evaluate the safety and efficacy of carbon ion radiotherapy (C-ion RT) for 80 years or older patients with hepatocellular carcinoma (HCC).

    Authors: Shintaro Shiba, Takanori Abe, Kei Shibuya, Hiroyuki Katoh, Yoshinori Koyama, Hirohumi Shimada, Satoru Kakizaki, Ken Shirabe, Hiroyuki Kuwano, Tatsuya Ohno and Takashi Nakano

    Citation: BMC Cancer 2017 17:721

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  17. Content type: Case report

    Hereditary diffuse gastric carcinoma (HDGC) accounts for 1–3% of all gastric carcinomas. Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in the gastrointestinal (GI) tract but th...

    Authors: Huijie Fan, Pei Lu, Li Xu, Yanru Qin and Jing Li

    Citation: BMC Cancer 2017 17:720

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  18. Content type: Research article

    Cancer stem cells (CSCs) are considered to be the major factor in tumor initiation, progression, metastasis, recurrence and chemoresistance. Maintaining the stemness and promoting differentiation of these cell...

    Authors: Xiaofeng Yu, Lin Mi, Jie Dong and Jian Zou

    Citation: BMC Cancer 2017 17:716

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  19. Content type: Research article

    Most efforts to advance cancer survivorship care have occurred in Western countries. There has been limited research towards gaining a comprehensive understanding of survivorship care provision in the Asia-Pac...

    Authors: Raymond Javan Chan, Patsy Yates, Qiuping Li, Hiroko Komatsu, Violeta Lopez, Myat Thandar, Selva Titus Chacko, Winnie Kwok Wei So, Kanaungnit Pongthavornkamol, Myungsun Yi, Pongpak Pittayapan, Jessica Butcon, David Wyld and Alex Molassiotis

    Citation: BMC Cancer 2017 17:715

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  20. Content type: Case report

    Multiple Myeloma is a cancer of plasma cells associated with significantly reduced survival. Long term survivorship from myeloma is very rare and despite advances in its treatment the disease is generally cons...

    Authors: Vallari Shah, Kevin D. Boyd, Richard S. Houlston and Martin F. Kaiser

    Citation: BMC Cancer 2017 17:718

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  21. Content type: Research article

    Gastrointestinal stromal tumours (GIST) are rarely encountered mesenchymal tumours of the gastrointestinal tract (1.5 people per 100,000/year) that are even more rarely seen in paediatric patients (1–2% of all...

    Authors: Piotr Rutkowski, Heather Magnan, Alexander J. Chou and Charlotte Benson

    Citation: BMC Cancer 2017 17:717

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  22. Content type: Case report

    Adequate working space and a clear view for the dissected lesion are crucial for endoscopic submucosal dissection (ESD). Pharyngeal ESD requires that an otorhinolaryngologist creates working space by lifting t...

    Authors: Lianjun Di, Kuang-I Fu, Rui Xie, Xinglong Wu, Youfeng Li, Huichao Wu and Biguang Tuo

    Citation: BMC Cancer 2017 17:712

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  23. Content type: Research article

    Many studies have combined sorafenib with transcatheter arterial chemoembolization (TACE) to treat patients with advanced hepatocellular carcinoma (HCC), but the results are disputable. Thus, we conducted this...

    Authors: Rong Cai, Rongfeng Song, Pengfei Pang, Yan Yan, Yifeng Liao, Cuiling Zhou, Shuncong Wang, Xiuling Zhou, Huaping Wang, Hongyu Zhang, Huanhuan Sun and Haiqing Ma

    Citation: BMC Cancer 2017 17:714

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