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  1. To compare the clinical value of recombinant human granulocyte colony-stimulating factor (rhG-CSF) and pegylated rhG-CSF(PEG-rhG-CSF) in early-stage breast cancer (EBC) patients receiving adjuvant chemotherapy...

    Authors: Yantao Jiang, Ju Zhang, Jianxin Zhong, Hao Liao, Jiayang Zhang, Yaxin Liu, Yuehua Liang and Huiping Li
    Citation: BMC Cancer 2023 23:702
    Content type: Research Published on:

  3. Drug resistance is a major cause of the inefficacy of conventional cancer therapies, and often accompanied by severe side effects. Thus, there is an urgent need to develop novel drugs with low cytotoxicity, hi...

    Authors: Youssef T. Abdou, Sheri M. Saleeb, Khaled M. A. Abdel-Raouf, Mohamed Allam, Mustafa Adel and Asma Amleh
    Citation: BMC Cancer 2023 23:699
    Content type: Research Published on:

  5. Authors: Qingwu Du, Xiaoyue Wu, Kunning Zhang, Fuliang Cao, Gang Zhao, Xiaoying Wei, Zhoubo Guo, Yang Li, Jie Dong, Tian Zhang, Wencheng Zhang, Ping Wang, Xi Chen and Qingsong Pang
    Citation: BMC Cancer 2023 23:697
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2023 23:681

  6. Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors with a high prevalence and poor prognosis. It is an urgent problem to deeply understand the molecular mechanism of ESCC and ...

    Authors: Honggang Liu, Menglong Jiang, Fenghui Ma, Jiapei Qin, Xin Zhou, Liqun Xu, Xiaolong Yan and Tao Jiang
    Citation: BMC Cancer 2023 23:696
    Content type: Research Published on:

  7. The site of lymph node metastasis (LNM) may affect the prognosis of patients with esophageal squamous cell carcinoma (ESCC). To investigate the prognoses of pararespiratory and paradigestive LNM and to propose...

    Authors: Dong Tian, Kai-Yuan Jiang, Yu-Shang Yang, Hao-Ji Yan, Rui-Xuan Yu, Heng Huang, Shun-Hai Jian, Hai-Ning Zhou, Hong-Ying Wen and Long-Qi Chen
    Citation: BMC Cancer 2023 23:695
    Content type: Research Published on:

  8. The Pegylated recombinant human granulocyte colony stimulating factor (PEG-rhG-CSF) has longer half-life and is given once only, which is more comfortable for patients. We aimed to evaluate the efficacy of mec...

    Authors: Jingjing Wen, Qiaolin Zhou, Lin Shi, Fang Xu, Yiping Liu, Jing Su, Ya Zhang, Wen Qu and Jing Yue
    Citation: BMC Cancer 2023 23:694
    Content type: Research Published on:

  10. As a component of membrane lipids and the precursor of oxysterols and steroid hormones, reprogrammed cholesterol metabolism contributes to the initiation and progression of multiple cancers. Thus, we aim to fu...

    Authors: Rui Tao, Ruoyu Huang, Jingchen Yang, Jiangfei Wang and Kuanyu Wang
    Citation: BMC Cancer 2023 23:692
    Content type: Research Published on:

  11. Although 80% of patients with metastatic colorectal cancer (CRC) experience liver metastases, only 10–25% undergo resection at the time of diagnosis. Even in initially unresectable conditions, if appropriate t...

    Authors: Ji Su Kim, Hyunwook Kim, Seo Young Lee, Yoon Dae Han, Kichang Han, Byung Soh Min, Man-Deuk Kim, Jong Yun Won, Seung-Hoon Beom, Sang Joon Shin, Han Sang Kim, Dai Hoon Han and Joong Bae Ahn
    Citation: BMC Cancer 2023 23:691
    Content type: Study protocol Published on:

  12. Our previous work showed that KRAS activation in gastric cancer cells leads to activation of an epithelial-to-mesenchymal transition (EMT) program and generation of cancer stem-like cells (CSCs). Here we analy...

    Authors: Changhwan Yoon, Jun Lu, Yukyung Jun, Yun-Suhk Suh, Bang-Jin Kim, Jacob E. Till, Jong Hyun Kim, Sara H. Keshavjee, Sandra Ryeom and Sam S. Yoon
    Citation: BMC Cancer 2023 23:690
    Content type: Research Published on:

  13. Despite recent advances in research, there are still critical lacunae in our basic understanding of the cause, pathogenesis, and natural history of many cancers, especially heterogeneity in patient response to...

    Authors: Swati Chitrangi, Pooja Vaity, Aishwarya Jamdar and Shweta Bhatt
    Citation: BMC Cancer 2023 23:689
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2023 23:768

  14. Numerous studies have demonstrated long noncoding RNA (lncRNA) play an important role in the occurrence and progression of cancer, and single nucleotide polymorphisms (SNPs) located in lncRNA are considered to...

    Authors: Maoquan Yang, Mingwei Zhang, Qiong Wang, Xiaojing Guo, Peizhen Geng, Jinhua Gu, Wansheng Ji and Li Zhang
    Citation: BMC Cancer 2023 23:688
    Content type: Research Published on:

  15. Breast cancer (BC) is a significant health concern among European women, with the highest prevalence rates among all cancers. Existing BC prediction models account for major risks such as hereditary, hormonal ...

    Authors: Elly Mertens, Antonio Barrenechea-Pulache, Diana Sagastume, Maria Salve Vasquez, Stefanie Vandevijvere and José L. Peñalvo
    Citation: BMC Cancer 2023 23:687
    Content type: Research Published on:

  16. SETD2 protects against genomic instability via maintenance of homologous recombination repair (HRR) and mismatch repair (MMR) in neoplastic cells. However, it remains unclear whether SETD2 dysfunction is a comple...

    Authors: Xiaobin Zheng, Jing Lin, Jiani Xiong, Yanfang Guan, Bin Lan, Yi Li, Xuan Gao, Zhaodong Fei, Lisha Chen, Lizhu Chen, Ling Chen, Gang Chen, Zengqing Guo, Xin Yi, Weiguo Cao, Xinghao Ai…
    Citation: BMC Cancer 2023 23:686
    Content type: Research Published on:

  17. Authors: Anine Larsen Ottestad, Håkon Johansen, Tarje Onsøien Halvorsen, Hong Yan Dai, Sissel Gyrid Freim Wahl, Elisabeth Fritzke Emdal and Bjørn Henning Grønberg
    Citation: BMC Cancer 2023 23:685
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2023 23:646

  19. High risk human papillomaviruses (HR-HPV) have a causal role in cervical oncogenesis, and HIV-mediated immune suppression allows HR-HPV to persist. We studied whether vaginal microbiome community state types (...

    Authors: Jonah Musa, Mamoudou Maiga, Stefan J. Green, Francis A. Magaji, Ali J. Maryam, Mark Okolo, Chuwang J. Nyam, Nanma T. Cosmas, Olugbenga A. Silas, Godwin E. Imade, Yinan Zheng, Brian T. Joyce, Brehima Diakite, Imran Morhason-Bello, Chad J. Achenbach, Atiene S. Sagay…
    Citation: BMC Cancer 2023 23:683
    Content type: Research Published on:

  20. Tigecycline has a broad spectrum of antimicrobial activity and has been approved for the treatment of complicated intra-abdominal infections. However, it is debatable whether tigecycline should be used alone o...

    Authors: Xinfeng Cai, Hongxia Yan, Wenjun Zhang, Wei Zhao, Lei Zhang, Xu Wang, Xinjing Wu, Zhiying Hao and Jinlin Guo
    Citation: BMC Cancer 2023 23:682
    Content type: Research Published on:

  21. Endoscopic ultrasound (EUS) may play a role in evaluating treatment response after definitive chemoradiation therapy (dCRT) for esophageal squamous cell carcinoma (ESCC). This study explored the prognostic mar...

    Authors: Qingwu Du, Xiaoyue Wu, Kunning Zhang, Fuliang Cao, Gang Zhao, Xiaoying Wei, Zhoubo Guo, Yang Li, Jie Dong, Tian Zhang, Wencheng Zhang, Ping Wang, Xi Chen and Qingsong Pang
    Citation: BMC Cancer 2023 23:681
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2023 23:697

  23. Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women. Approximately 50% of breast cancers are discovered at an early stage in patients for whom conservative surg...

    Authors: Hugo Veyssiere, Margot Dressaire, Raphaël Pete, Céleste Pinard, Ioana Molnar, Catherine Abrial, Angeline Ginzac, Xavier Durando and Marielle Tekath
    Citation: BMC Cancer 2023 23:679
    Content type: Study protocol Published on:

  24. Interindividual survival and recurrence rates in cases of locoregional colon cancer following surgical resection are highly variable. The aim of the present study was to determine whether elevated pre-operativ...

    Authors: Wendy R. Muñoz-Montaño, Horacio N. López-Basave, Alison Castillo-Morales, Carolina Castillo-Morales, Karen Sánchez-Trejo, Rodrigo Catalán, Consuelo Díaz-Romero, Leonardo S. Lino-Silva, Andrea Maliachi-Díaz, Erika Ruiz-García, Marytere Herrera-Martínez and German Calderillo-Ruíz
    Citation: BMC Cancer 2023 23:678
    Content type: Research Published on:

  25. The accumulation of lipid droplets (LDs) in hepatocytes is the main pathogenesis in nonalcoholic fatty liver disease (NAFLD), which is also the key risk factor for the progression of hepatocellular carcinoma (...

    Authors: Yize Zhang, Xue Liang, Qinghai Lian, Liwen Liu, Baoyu Zhang, Zihui Dong and Kunpeng Liu
    Citation: BMC Cancer 2023 23:677
    Content type: Research Published on:

  26. Rat sarcoma viral oncogene homolog (RAS) gene mutation is a common molecular event in colorectal cancer (CRC). The prognosis of mCRC (metastatic colorectal cancer) patients with RAS mutation is poor and capeci...

    Authors: Xuefeng Fang, Chenhan Zhong, Shanshan Weng, Hanguang Hu, Jian Wang, Qian Xiao, Jianwei Wang, Lifeng Sun, Dong Xu, Xiujun Liao, Caixia Dong, Suzhan Zhang, Jun Li, Kefeng Ding and Ying Yuan
    Citation: BMC Cancer 2023 23:676
    Content type: Study Protocol Published on:

  27. Current guidelines only propose the importance of perineural invasion(PNI) on prognosis in stage II colon cancer. However, the prognostic value of PNI in other stages of colorectal cancer (CRC) is ambiguous.

    Authors: Bin Zhang, Yanyun Lin, Chao Wang, Zexian Chen, Tianze Huang, Hao Chen, Guannan Wang, Ping Lan, Xiaowen He and Xiaosheng He
    Citation: BMC Cancer 2023 23:675
    Content type: Research Published on:

  28. Annexins are a family of proteins involved in a wide variety of cellular processes such as inflammation, proliferation, differentiation, apoptosis, migration and membrane repair. However, the role of most Anne...

    Authors: Li-Hui Wang, Bo Cao, Yun-Long Li and Bao-Ping Qiao
    Citation: BMC Cancer 2023 23:674
    Content type: Research Published on:

  29. Analyzing the prognostic value of Epstein-Barr virus (EBV) DNA load and platelet-to-lymphocyte ratio (PLR) in non-metastatic nasopharyngeal carcinoma (NPC) patients, thereby developing a reliable and effective...

    Authors: Huan Dong, Zichong Huang, Dong Yang, Zhiru Li, Heqing Huang, Zhen Meng, Yutao Qin and Min Kang
    Citation: BMC Cancer 2023 23:673
    Content type: Research Published on:

  31. Previous studies have shown that Family with sequence similarity 134 member B (FAM134B) was involved in the occurrence and development of malignancy, however, the function and molecular mechanism of FAM134B in...

    Authors: Binhui Xie, Yuankang Xie, Cuifu Fang, Baiyin Zhong, Rong Ye, Jianhong Zhang, Qingquan Liu and Heping Li
    Citation: BMC Cancer 2023 23:671
    Content type: Research Published on:

  32. Neuroblastoma (NB) is a childhood malignant tumor,50% of high-risk NB children still have recurrence, and the long-term survival rate is very low. NB tumors expressing high levels of BDNF/TrkB are associated w...

    Authors: Xilin Xiong, Meiling Zeng, Xiaomin Peng, Chuchu Feng, Chunmou Li, Wenjun Weng and Yang Li
    Citation: BMC Cancer 2023 23:670
    Content type: Research Published on:

  33. Patients diagnosed with esophageal cancer demonstrate a low overall survival even despite the established multimodal therapy as the current standard of care. Therefore, further biomarkers for patients with hig...

    Authors: Karl Knipper, Alexander I. Damanakis, Su Ir Lyu, Adrian Georg Simon, Isabell Wahler, Christiane J. Bruns, Wolfgang Schröder, Thomas Schmidt and Alexander Quaas
    Citation: BMC Cancer 2023 23:669
    Content type: Research Published on:

  34. Studies have shown that microRNA-191 (miR-191) is involved in the development and progression of a variety of tumors. However, the function and mechanism of miR-191 in oral squamous cell carcinoma (OSCC) have ...

    Authors: Zekun Wang, Wenzhao Guan, Yufeng Ma, Xuedong Zhou, Guohua Song, Jianing Wei and Chenyang Wang
    Citation: BMC Cancer 2023 23:668
    Content type: Research Published on:

  35. Seroma is the most common complication following breast cancer surgery, with reported incidence up to 90%. Seroma causes patient discomfort, is associated with surgical site infections (SSI), often requires tr...

    Authors: L. J. van Zeelst, B. ten Wolde, J. D. J. Plate, J. H. Volders, R.R.J.P. van Eekeren, A. Doeksen, M. L. Hoven-Gondrie, A. F. T. Olieman, Y. E. A. van Riet, A. P. Schouten van der Velden, S. Vijfhuize, H. H. G. Witjes, J. H. W. de Wilt and L. J. A. Strobbe
    Citation: BMC Cancer 2023 23:667
    Content type: Study protocol Published on:

  37. Cancer risk varies geographically, and migrants are influenced by different risk factors before, during and after migration. Increased migration from non-Western countries to the Nordic countries calls for a b...

    Authors: Maarit Lamminmäki, Aku Leivonen, Sirpa Heinävaara, Mari Nygård, Giske Ursin, Suzanne Campbell, Hrefna Stefansdóttir, Elli Hirvonen, Salla Toikkanen, Ilse Merete Munk Vejborg, Sisse Helle Njor and Tytti Sarkeala
    Citation: BMC Cancer 2023 23:665
    Content type: Research Published on:

  38. Although there is extensive literature on correlates of health-related quality of life (HRQoL) among cancer survivors, there has been less attention paid to the role of socioeconomic disadvantage and survivors...

    Authors: Sharon Manne, Katie Devine, Shawna Hudson, Deborah Kashy, Denalee O’Malley, Lisa E. Paddock, Elisa V. Bandera, Adana A. M. Llanos, Angela Fong, Neetu Singh, Sara Frederick and Andrew M. Evens
    Citation: BMC Cancer 2023 23:664
    Content type: Research Published on:

  39. Patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M-HNSCC) have a poor prognosis and limited therapeutic options. Immune checkpoint inhibitors (ICIs) are effective in patients with...

    Authors: Agathe Vienne, Laetitia Collet, Thomas Chevalier, Christian Borel, Magalie Tardy, Florence Huguet, Sandrine Richard, Sebastien Salas, Esma Saada-Bouzid, Jerome Fayette and Amaury Daste
    Citation: BMC Cancer 2023 23:663
    Content type: Research Published on:

  40. Clinical studies have shown that first-line use of anti-angiogenetic therapy can prolong progression-free survival but little progress has been made in extending the overall survival of the patients. We explor...

    Authors: Mou Yueyang, Hu Yaqin, Xue Guolian, Zhao Wenjian, Jiao Yang, Li Chen, Cao Haiyan, Chao Min, Deng Jianping, Dai Penggao, Zhu Hongli and Wang Liang
    Citation: BMC Cancer 2023 23:662
    Content type: Research Published on:

  41. V domain Immunoglobulin suppressor of T cell activation (VISTA) has been proved to be a novel immune checkpoint molecule that positively regulates T cell infiltration in several malignancies. However, the clin...

    Authors: Wandi Li, Zhaopei Liu, Kaifeng Jin, Fei Shao, Han Zeng, Yiwei Wang, Yu Zhu, Le Xu, Zewei Wang, Yuan Chang and Weijuan Zhang
    Citation: BMC Cancer 2023 23:661
    Content type: Research Published on:

  43. In non-small cell lung cancer (NSCLC), there may be a relationship between programmed death-ligand 1 (PD-L1) expression, driver mutations and cigarette smoking.

    Authors: Chong Kin LIAM, Chian Yih YEW, Yong Kek PANG, Chee Kuan WONG, Mau Ern POH, Jiunn Liang TAN, Chun Ian SOO, Thian Chee LOH, Ka Kiat CHIN, Vijayan MUNUSAMY, Yong Sheng LIAM and Nur Husna IBRAHIM
    Citation: BMC Cancer 2023 23:659
    Content type: Research Published on:

  44. Recurrences are the main reasons for unfavorable outcomes for patients with stage II colorectal cancer (CRC). To obtain a clear understanding of the high-risk factors, further investigation is warranted. The p...

    Authors: Zhi-Zhong Xiong, Ming-Hao Xie, Xian-Zhe Li, Long-Yang Jin, Feng-Xiang Zhang, Shi Yin, Hua-Xian Chen and Lei Lian
    Citation: BMC Cancer 2023 23:658
    Content type: Research article Published on:

  45. Bile duct obstruction is a common issue for patients with advanced cholangiocarcinoma (CCA). Percutaneous transhepatic cholangial drainage (PTCD) is often required to relieve the obstruction. However, PTCD may...

    Authors: Qingyu Huang, Fuhao Wang, Xiang Zhang, Jing Liu, Xue Dou, Rui Feng, Kunli Zhu, Shumei Jiang, Yun Zhang and Jinbo Yue
    Citation: BMC Cancer 2023 23:657
    Content type: Research Published on:

  46. Breast cancer (BC) with low human epidermal growth factor receptor 2 (HER2) expression is attracting much attention due to the breakthrough progress of novel anti-HER2 antibody-drug conjugates. HER2 expression...

    Authors: Mengyuan Cai, Ming Li, Hong Lv, Shuling Zhou, Xiaoli Xu, Ruohong Shui and Wentao Yang
    Citation: BMC Cancer 2023 23:656
    Content type: Research Published on:

  47. The utilization of modern-immunotherapies, notably immune checkpoint inhibitors (ICIs), has increased markedly in patients with metastatic melanoma over the past decade and are recommended as standard treatmen...

    Authors: Olajumoke A. Olateju, Zhen Zeng, J. Douglas Thornton, Osaro Mgbere and Ekere James Essien
    Citation: BMC Cancer 2023 23:655
    Content type: Research Published on:

  48. Cancer cells release heterogeneous populations of extracellular vesicles (EVs) that transmit aggressive phenotypic traits to recipient cells. We aimed to establish if the heterogenous EVs population or a sub-p...

    Authors: Niamh McNamee, Mariadelva Catalano, Anindya Mukhopadhya and Lorraine O’Driscoll
    Citation: BMC Cancer 2023 23:654
    Content type: Research Published on:

  49. Radioimmunotherapy with cetuximab and conjugates with various radioisotopes is a feasible treatment option for different tumor models. Scandium-47 (47Sc), one of several β−-particle-emitting radioisotopes, displa...

    Authors: Da-Mi Kim, So-Young Lee, Jae-Cheong Lim, Eun-Ha Cho and Ul-Jae Park
    Citation: BMC Cancer 2023 23:652
    Content type: Research Published on:

  50. Clear cell renal cell carcinoma (ccRCC) is the most common renal malignancy, although newly developing targeted therapy and immunotherapy have been showing promising effects in clinical treatment, the effectiv...

    Authors: Ziwei Gui, Juan Du, Nan Wu, Ningning Shen, Zhiqing Yang, Huijun Yang, Xuzhi Wang, Na Zhao, Zixin Zeng, Rong Wei, Wenxia Ma and Chen Wang
    Citation: BMC Cancer 2023 23:649
    Content type: Research Published on:

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