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  1. Colorectal cancer is the third most diagnosed cancer globally and the second leading cause of cancer death. We examined colon and rectal cancer treatment patterns in Australia.

    Authors: Sarsha Yap, Emily He, Sam Egger, David E Goldsbury, Jie-Bin Lew, Preston J Ngo, Joachim Worthington, Hannah Rillstone, John R Zalcberg, Jeff Cuff, Robyn L Ward, Karen Canfell, Eleonora Feletto and Julia Steinberg
    Citation: BMC Cancer 2023 23:60
    Content type: Research Published on:

  2. Saroglitazar is a novel PPAR-α/γ agonist with predominant PPAR-α activity. In various preclinical models, saroglitazar has been shown to prevent & reverse symptoms of NASH. In view of these observations, and t...

    Authors: Suresh R. Giri, Bibhuti Bhoi, Chitrang Trivedi, Akshyaya Rath, Rohan Rathod, Anish Sharma, Ramchandra Ranvir, Shekhar Kadam, Kailash Ingale, Hiren Patel, Abraham Nyska and Mukul R. Jain
    Citation: BMC Cancer 2023 23:59
    Content type: Research Published on:

  3. CT is the major detection tool for pancreatic cancer (PC). However, approximately 40% of PCs < 2 cm are missed on CT, underscoring a pressing need for tools to supplement radiologist interpretation.

    Authors: Dawei Chang, Po-Ting Chen, Pochuan Wang, Tinghui Wu, Andre Yanchen Yeh, Po-Chang Lee, Yi-Hui Sung, Kao-Lang Liu, Ming-Shiang Wu, Dong Yang, Holger Roth, Wei-Chih Liao and Weichung Wang
    Citation: BMC Cancer 2023 23:58
    Content type: Research Published on:

  4. Circadian clock genes are significant in the occurrence and development of HCC and long-non coding RNAs (lncRNAs) are closely related to HCC progression. In this study, we aimed to establish a prognostic risk ...

    Authors: Zhen Zhang, Wenhui Gao, Xiaoning Tan, Tianhao Deng, Wanshuang Zhou, Huiying Jian and Puhua Zeng
    Citation: BMC Cancer 2023 23:57
    Content type: Research Published on:

  5. Computed tomography (CT) derived body composition measurements of sarcopenia are an emerging form of prognostication in many disease processes. Although the L3 vertebral level is commonly used to measure skel...

    Authors: Aisha A Arayne, Richard Gartrell, Jing Qiao, Paul N Baird and Justin MC Yeung
    Citation: BMC Cancer 2023 23:56
    Content type: Research Published on:

  6. Macrophage infiltration in the tumor microenvironment participates in the regulation of tumor progression. Previous studies have found that Notch signaling pathway is involved in regulating the progression of ...

    Authors: Kai Huang, Wenwu Luo, Jinmei Fang, Changjun Yu, Guangjie Liu, Xiaodong Yuan, Yun Liu and Wenyong Wu
    Citation: BMC Cancer 2023 23:55
    Content type: Research Published on:

  7. Ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles are of potential magnetic resonance imaging (MRI) contrast agents for tumor diagnosis. However, ultrasmall particle size or negative surface charge...

    Authors: Changyuan Wang, Yang Wang, Wangchuan Xiao, Xiaohua Chen, Renfu Li, Zhiyong Shen and Fengchun Lu
    Citation: BMC Cancer 2023 23:54
    Content type: Research Published on:

  8. The role of preoperative serum tumor markers in HAS patients was vague, we designed the study to explore the effect of preoperative serum tumor markers on predicting the prognosis of HAS patients.

    Authors: Xuesong Yang, Anqiang Wang, Jialin Li, Kai Zhou, Ke Ji, Xin Ji, Ji Zhang, Xiaojiang Wu and Zhaode Bu
    Citation: BMC Cancer 2023 23:53
    Content type: Research Published on:

  9. TGF-β-induced factor homeobox 2 (TGIF2) is a transcription regulator that is phosphorylated by EGFR/ERK signaling. However, the functions of phosphorylated (p)-TGIF2 in cancer are largely unknown. Here, we inv...

    Authors: Renle Du, Chen Wang, Jingjing Liu, Keyan Wang, Liping Dai and Wenzhi Shen
    Citation: BMC Cancer 2023 23:52
    Content type: Research Published on:

  10. Currently, the standard treatment for locally advanced cervical cancer is concurrent chemoradiation (CCRT). Forty percent of patients present with disease recurrence. This study aims to investigate the feasibi...

    Authors: Jing Li, Ya Li, Huafeng Wang, Lifei Shen, Qun Wang, Siqi Shao, Yuhong Shen, Haoping Xu, Hua Liu, Rong Cai and Weiwei Feng
    Citation: BMC Cancer 2023 23:51
    Content type: Research Published on:

  11. To investigate the predictive value of metabolic syndrome (MetS) and its components in biochemical recurrence (BCR) and adverse pathological features of patients with prostate cancer (PCa) after radical prosta...

    Authors: Zenan Liu, Xuehua Zhu, Jide He and Jian Lu
    Citation: BMC Cancer 2023 23:50
    Content type: Research Published on:

  12. With the advent of intensive combination regimens, an increasing number of patients with unresectable pancreatic cancer (UPC) have regained the opportunity for surgery. We investigated the clinical benefits an...

    Authors: Xiang Li, Xinyuan Liu, Na Lu, Yiwen Chen, Xiaochen Zhang, Chengxiang Guo, Wenbo Xiao, Xing Xue, Ke Sun, Meng Wang, Shunliang Gao, Yan Shen, Min Zhang, Jian Wu, Risheng Que, Jun Yu…
    Citation: BMC Cancer 2023 23:49
    Content type: Research Published on:

  13. Primary myelofibrosis [PMF] is a myeloproliferative neoplasm associated with reduced overall survival (OS). Management strategies for PMF have evolved over the last two decades, including approval of ruxolitin...

    Authors: Tsewang Tashi, Jingbo Yu, Shivani Pandya, Christopher Dieyi, Robyn Scherber and Shreekant Parasuraman
    Citation: BMC Cancer 2023 23:48
    Content type: Research Published on:

  14. New concepts for a more effective anti-cancer therapy are urgently needed. Experimental flaws represent a major counter player of this development and lead to inaccurate and unreproducible data as well as unsu...

    Authors: Senyao Shao, Lars Uwe Scholtz, Sarah Gendreizig, Laura Martínez-Ruiz, Javier Florido, Germaine Escames, Matthias Schürmann, Carsten Hain, Leonie Hose, Almut Mentz, Pascal Schmidt, Menghang Wang, Peter Goon, Michael Wehmeier, Frank Brasch, Jörn Kalinowski…
    Citation: BMC Cancer 2023 23:47
    Content type: Research Published on:

  16. Tumor microenvironment (TME) is of great importance to regulate the initiation and advance of cancer. The immune infiltration patterns of TME have been considered to impact the prognosis and immunotherapy sens...

    Authors: Yinghe Ding, Ling Chu, Qingtai Cao, Hanyu Lei, Xinyu Li and Quan Zhuang
    Citation: BMC Cancer 2023 23:45
    Content type: Research Published on:

  17. The vast majority of ovarian mucinous carcinomas are metastatic tumours derived from nonovarian primary cancers, typically gastrointestinal neoplasms. Therapy targeting claudin18.2 might be used in gastric, ga...

    Authors: Fujun Wang, Yao Yang, Xiuzhen Du, Xiaoying Zhu, Yanjiao Hu, Changyu Lu, Lei Sui, Han Zhao, Kejuan Song and Qin Yao
    Citation: BMC Cancer 2023 23:44
    Content type: Research Published on:

  18. Porphyromonas gingivalis plays an oncogenic role in development and progression of esophageal squamous cell carcinoma (ESCC). However, the impact of P. gingivalis on local recurrence of early ESCC or precancerous...

    Authors: She-Gan Gao, Zhi-Peng Qi, Yi-Jun Qi, Ying-Yong Hou, Yi-Wen Liu, Meng-Xiang Li, Bing Li, Di Sun, Qiang Shi, Shi-Lun Cai, Ping-Hong Zhou and Yun-Shi Zhong
    Citation: BMC Cancer 2023 23:43
    Content type: Research Published on:

  19. This study aimed to develop an integrated model for predicting the occurrence of postoperative seizures in patients with diffuse high-grade gliomas (DHGGs) using clinical and RNA-seq data.

    Authors: Lianwang Li, Chuanbao Zhang, Zheng Wang, Yinyan Wang, Yuhao Guo, Chong Qi, Gan You, Zhong Zhang, Xing Fan and Tao Jiang
    Citation: BMC Cancer 2023 23:42
    Content type: Research Published on:

  20. Due to inconsistency in neoadjuvant chemotherapy (NACT) response in advanced gastric cancer (GC), the indications remain the source of controversy. This study focused on identifying factors related to NACT che...

    Authors: Xian-Wen Liang, Wei-Sheng Xiao, Hao Lei, Qian-Cheng Huag, Yu-Lan Dong, Fang Wang and Wei-Peng Qing
    Citation: BMC Cancer 2023 23:41
    Content type: Research Published on:

  21. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zheqiong Tan, Yaru Zou, Man Zhu, Zhenzhao Luo, Tangwei Wu, Chao Zheng, Aqing Xie, Hui Wang, Shiqiang Fang, Shuiyi Liu, Yong Li and Zhongxin Lu
    Citation: BMC Cancer 2023 23:40
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2021 21:409

  22. Colorectal cancer (CRC), ranking third in cancer prevalence and second in mortality worldwide, is mainly derived from colorectal adenoma (CRA). CRA is a common benign disease in the intestine with rapidly incr...

    Authors: Bangting Wang, Jiting Zhang, Xin Wang, Lili Zhao, Yan Wang, Zhining Fan, Li Liu and Wenqing Gao
    Citation: BMC Cancer 2023 23:39
    Content type: Research Published on:

  23. Gastrointestinal stromal tumor (GIST) is currently regarded as a potentially malignant tumor, and early diagnosis is the best way to improve its prognosis. Therefore, it will be meaningful to develop a new met...

    Authors: Lianhuang Li, Xingxin Huang, Shichao Zhang, Zhenlin Zhan, Deyong Kang, Guoxian Guan, Shuoyu Xu, Yongjian Zhou and Jianxin Chen
    Citation: BMC Cancer 2023 23:38
    Content type: Research Published on:

  24. As a first-line imaging modality, whole-body fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) and 18F-FDG PET/magnetic resonance imaging (MRI) had been widel...

    Authors: Cici Zhang, Zhishan Liang, Wei Liu, Xuwen Zeng and Yuzhen Mo
    Citation: BMC Cancer 2023 23:37
    Content type: Research Published on:

  25. Lung cancer is one of the most lethal tumors with a poor survival rate even in those patients receiving new therapies. Metabolism is considered one of the hallmarks in carcinogenesis and lipid metabolism is em...

    Authors: María Merino Salvador, Lara Paula Fernández, Juan Moreno-Rubio, Gonzalo Colmenarejo, Enrique Casado, Ana Ramírez de Molina and María Sereno
    Citation: BMC Cancer 2023 23:36
    Content type: Research Published on:

  26. Cancer-related cognitive impairment (CRCI) is one of the most concerning conditions experienced by patients living with cancer and has a major impact on their quality of life. Available cognitive assessment to...

    Authors: Amel Baghdadli, Giovanni G. Arcuri, Clarence G. Green, Lynn R. Gauthier, Pierre Gagnon and Bruno Gagnon
    Citation: BMC Cancer 2023 23:35
    Content type: Research Published on:

  27. All cell types express long non-coding RNAs (lncRNAs), which have the potential to play a role in carcinogenesis by altering the levels of their expression. Squamous cell carcinoma of the esophagus (ESCC) is a...

    Authors: Zahra Roohinejad, Shabbou Bahramian, Fatemeh Tash Shamsabadi, Reza Sahebi, Abolfazl Amini, Davood Sabour and Mohammad Shafiee
    Citation: BMC Cancer 2023 23:34
    Content type: Research Published on:

  28. Diminished immune defense plays an important role in cancer development. Cancer risk in immunocompromised patients may differ. Identifying individuals with elevated cancer risk can inform strategies for routin...

    Authors: Sabrina Ilham, Connor Willis, Kibum Kim, Karen C. Chung, Brenda M. Wood, Malinda S. Tan, Chia Jie Tan, Danielle T. Nguyen, Diana I. Brixner and David D. Stenehjem
    Citation: BMC Cancer 2023 23:33
    Content type: Research Published on:

  29. The link between immediate hypersensitivity reactions (HSR) following the first cetuximab infusion and the IgE sensitization against anti-galactose-α-1,3-galactose (α-Gal) is now well-established. An automated...

    Authors: Julien Serrier, Jean-Baptiste Davy, Benoît Dupont, Bénédicte Clarisse, Jean-Jacques Parienti, Gautier Petit, Kathy Khoy, Yann Ollivier, Radj Gervais, Delphine Mariotte and Brigitte Le Mauff
    Citation: BMC Cancer 2023 23:32
    Content type: Research Published on:

  30. To compare recurrence and survival in patients with stage III endometrial cancer after radical surgery, followed by either adjuvant chemoradiotherapy (ACR) or adjuvant chemotherapy (AC).

    Authors: Si-yu Cao, Yu Fan, Yu-fei Zhang, Jia-ying Ruan, Yi Mu and Jin-ke Li
    Citation: BMC Cancer 2023 23:31
    Content type: Research Published on:

  31. Merkel cell carcinoma (MCC) is a rare but highly aggressive neuroendocrine skin malignancy, with Australia having the highest reported incidence in the world. There is currently a lack of consensus regarding o...

    Authors: Annie J. Wang, Brendan McCann, William C. L. Soon, Paolo B. De Ieso, Mathias Bressel, Andrew Hui, Margaret Chua and David L. Kok
    Citation: BMC Cancer 2023 23:30
    Content type: Research Published on:

  32. Despite the poor prognosis of triple-negative breast cancer (TNBC), it has been demonstrated that neoadjuvant immunotherapy in combination with chemotherapy can improve the pathologic complete response (pCR) r...

    Authors: Heran Deng, Liying Wang, Na Wang, Kejin Zhang, Yanxia Zhao, Pengfei Qiu, Xiaowei Qi, Danhua Zhang, Fei Xu and Jieqiong Liu
    Citation: BMC Cancer 2023 23:29
    Content type: Research Published on:

  33. Targeting deubiquitinases (DUBs) has emerged as a promising avenue for anticancer drug development. However, the effect and mechanism of pan-DUB inhibitor EOAI on non-small cell lung cancer (NSCLC) remains to ...

    Authors: Yuanyuan Zheng, Longhao Wang, Xiaoyu Niu, Yongjun Guo, Jiuzhou Zhao, Lifeng Li and Jie Zhao
    Citation: BMC Cancer 2023 23:28
    Content type: Research Published on:

  34. Early death remains a major factor in survival in APL. We aimed to analyze the risk factors for differentiation syndrome and early death in acute promyelocytic leukemia (APL).

    Authors: Jingjing Wen, Fang Xu, Qiaolin Zhou, Lin Shi, Yiping Liu, Jing Yue, Ya Zhang and Xiaogong Liang
    Citation: BMC Cancer 2023 23:27
    Content type: Research Published on:

  35. High-dose chemotherapy with autologous stem cell rescue (HDCT) is a promising treatment for patients with stage III, HER2-negative, homologous recombination deficient (HRD) breast cancer. Clinical effectivenes...

    Authors: Joost G. E. Verbeek, Vincent M. T. de Jong, Hanna M. Wijnja, Agnes Jager, Sabine C. Linn, Valesca P. Retèl and Wim H. van Harten
    Citation: BMC Cancer 2023 23:26
    Content type: Research article Published on:

  36. Hepatocellular carcinoma (HCC) is a common abdominal cancer with dissatisfactory therapeutic effects. The discovery of cuproptosis lights on new approach for cancer treatment and assessment. So far, there is e...

    Authors: Changwei Ke, Shejiao Dai, Fangshi Xu, Jia Yuan, Shuting Fan, Yang Chen, Longbao Yang and Yong Li
    Citation: BMC Cancer 2023 23:25
    Content type: Research Published on:

  37. P-glycoprotein (P-gp), a member of the ATP Binding Cassette B1 subfamily (ABCB1), confers resistance to clinically relevant anticancer drugs and targeted chemotherapeutics. However, paradoxically P-glycoprotei...

    Authors: Rowa Bakadlag, Georgia Limniatis, Gabriel Georges and Elias Georges
    Citation: BMC Cancer 2023 23:24
    Content type: Research Published on:

  38. The breast-conserving surgery and reconstruction rate in China is relatively low when compared with those in Western countries. Moreover, predictors of surgical choices for women with breast cancer in China ha...

    Authors: Sijia Huang, Qingmo Yang, Xujuan Zheng, Ka Ming Chow, Junhua Wu and Jiemin Zhu
    Citation: BMC Cancer 2023 23:23
    Content type: Research Published on:

  39. The Colorectal Cancer Screening Intervention for Malaysia (CRC-SIM) was a CRC study of home-based testing designed to improve low screening uptake using the immunochemical fecal occult blood test (iFOBT) in Ma...

    Authors: Désirée Schliemann, Kogila Ramanathan, Nor Saleha Binti Ibrahim Tamin, Ciaran O’Neill, Christopher R Cardwell, Roshidi Ismail, Zaid Kassim, Frank Kee, Tin Tin Su and Michael Donnelly
    Citation: BMC Cancer 2023 23:22
    Content type: Research Published on:

  40. The objective of this study was to assess the effectiveness of a Patient Navigation Intervention targeting deprived patients for Colo-Rectal Cancer (CRC) screening participation.

    Authors: A. Bourmaud, Y. Benoist, F. Tinquaut, C. Allary, J. Ramone-Louis, M. Oriol, J. Kalecinski, V. Dutertre, N. Lechopier, M. Pommier, S. Rousseau, A. Dumas, P. Amiel, V. Regnier, V. Buthion and F. Chauvin
    Citation: BMC Cancer 2023 23:21
    Content type: Research Published on:

  41. Tumor-associated neutrophils (TANs) in the tumor microenvironment are prognostic biomarkers in many malignancies. However, it is unclear whether TANs can serve as a prognostic marker for clinical outcomes in p...

    Authors: Xuezhen Wang, Xiaoxia Li, Yufan Wu, Jinsheng Hong and Mingwei Zhang
    Citation: BMC Cancer 2023 23:20
    Content type: Research Published on:

  42. Hepatocellular carcinoma (HCC) remains one of the most common and lethal malignancies worldwide. Although DBF4-dependent kinase (DDK) complex composed of CDC7 kinase and its regulatory subunit DBF4 has been sh...

    Authors: Min Wang, Zu-Hua Qiu, Yu-Zhuo Wang, Bo Lian, Jing-Kun Bai, Yong-Jie Zhou and Hong-Jie Ji
    Citation: BMC Cancer 2023 23:19
    Content type: Research Published on:

  44. We have done a systematic literature review about CRC Screening over 75 years old in order to update knowledge and make recommendations.

    Authors: Lydia Guittet, Valérie Quipourt, Thomas Aparicio, Elisabeth Carola, Jean-François Seitz, Elena Paillaud, Astrid Lievre, Rabia Boulahssass, Carole Vitellius, Leila Bengrine, Florence Canoui-Poitrine and Sylvain Manfredi
    Citation: BMC Cancer 2023 23:17
    Content type: Research Published on:

  45. Antiangiogenic drugs have shown initial efficacy in the treatment of advanced thymic carcinomas (TCs); however, data are limited. In this study, we provide real-world data relating to the efficacy of antiangio...

    Authors: Yelan Guan, Xiaodong Gu, Jinfei Si, Jing Xiang, Jingwen Wei, Yue Hao, Wenxian Wang and Yan Sun
    Citation: BMC Cancer 2023 23:16
    Content type: Research Published on:

  46. The objective of this paper is to explore the value of a delta-radiomic model of the axillary lymph node (ALN) using dynamic contrast-enhanced (DCE) MRI for early prediction of the axillary pathological comple...

    Authors: Shasha Liu, Siyao Du, Si Gao, Yuee Teng, Feng Jin and Lina Zhang
    Citation: BMC Cancer 2023 23:15
    Content type: Research Published on:

  47. No data on predicting the survival of AML patients based on the level of trace elements in the serum have been presented to date. The aims of this prospective cohort study were as follows: (i) to evaluate the ...

    Authors: Taotao Li, Liming Shi, Wei Wei, Jiancheng Xu and Qiuju Liu
    Citation: BMC Cancer 2023 23:14
    Content type: Research Published on:

  48. Immune checkpoint inhibitors, including PD-L1 (programmed death ligand-1) inhibitors have well documented anticancer therapeutic effect in most types of cancers but its use in the treatment of ovarian cancer i...

    Authors: Kholoud Alwosaibai, Salmah Aalmri, Miral Mashhour, Salim Ghandorah, Abdulraheem Alshangiti, Faisal Azam, Waleed Selwi, Lubna Gharaibeh, Yasser Alatawi, Zainab Alruwaii and Hashem O. Alsaab
    Citation: BMC Cancer 2023 23:13
    Content type: Research Published on:

  50. Mesenchymal circulating tumor cells (M-CTCs) may be related to tumor progression, and Ki67 expression is known to be involved in tumor proliferation. The aim of the present study was to explore the relationshi...

    Authors: Xihua Yang, Hanghang Ni, Zhan Lu, Jie Zhang, Qian Zhang, Shangwu Ning, Lunan Qi and Bangde Xiang
    Citation: BMC Cancer 2023 23:10
    Content type: Research Published on:

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