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  2. Cervical cancer is the fourth most common cancer in women, with an estimated 342,000 deaths worldwide in 2020. Current standard of care in the UK for locally advanced cervical cancer is concurrent chemoradioth...

    Authors: Peter Hoskin, Marina Lee, Denise Dunkley, Mary Danh, Robin Wickens, Geoff Saunders, Josh Northey, Simon Crabb, Vicky McFarlane, Azmat Sadozye, Rachel Cooper, Tony Mathew, Kate Haslett, Kim Reeves, Rachel Reed, Kamilla Bigos…
    Citation: BMC Cancer 2024 24:702
    Content type: Study Protocol Published on:

  3. Ovarian cancer is the first cause of death from gynecological malignancies mainly due to development of chemoresistance. Despite the emergence of PARP inhibitors, which have revolutionized the therapeutic mana...

    Authors: Lucie Thorel, Jordane Divoux, Justine Lequesne, Guillaume Babin, Pierre-Marie Morice, Romane Florent, Guillaume Desmartin, Lucie Lecouflet, Chloé Marde Alagama, Alexandra Leconte, Bénédicte Clarisse, Mélanie Briand, Roman Rouzier, Léopold Gaichies, Sandrine Martin-Françoise, Jean-François Le Brun…
    Citation: BMC Cancer 2024 24:701
    Content type: Study Protocol Published on:

  4. Although radical surgical resection is the most effective treatment for hepatocellular carcinoma (HCC), the high rate of postoperative recurrence remains a major challenge, especially in patients with alpha-fe...

    Authors: Xuanzhi Yan, Yicheng Li, Wanying Qin, Jiayi Liao, Jiaxing Fan, Yujin Xie, Zewen Wang, Siming Li and Weijia Liao
    Citation: BMC Cancer 2024 24:700
    Content type: Research Published on:

  5. [18F]Fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) is recommended during diagnostic work-up for ovarian cancer; however, [18F]FDG PET has several inherent limitations. The novel oncologic PET-t...

    Authors: Morten Bentestuen, Morten Ladekarl, Aage Knudsen and Helle D. Zacho
    Citation: BMC Cancer 2024 24:699
    Content type: Study Protocol Published on:

  6. Tumor-associated macrophages (TAMs) constitute a substantial part of human hepatocellular carcinoma (HCC). The present study was devised to explore TAM diversity and their roles in HCC progression.

    Authors: Shiqi Liu, Shuairan Zhang, Hang Dong, Xiuli Jin, Jing Sun, Haonan Zhou, Yifan Jin, Yiling Li and Gang Wu
    Citation: BMC Cancer 2024 24:698
    Content type: Research Published on:

  8. Inflammation, malnutrition, and cancer are intricately interconnected. Despite this, only a few studies have delved into the relationship between inflammatory malnutrition and the risk of death among cancer su...

    Authors: Chaoqun Liang, Chao Zhang, Jun Song, Lin Yan, Yun Xiao, Nan Cheng, Han Wu, Xiaohong Chen and Jianming Yang
    Citation: BMC Cancer 2024 24:696
    Content type: Research Published on:

  9. Cervical cancer (CxCa), although preventable, is still among the most prevalent cancers in women. Mortality from this cancer is high, especially in low-income countries where preventive strategies are often la...

    Authors: Boshra Ali, Andrzej Galbarczyk, Grazyna Jasienska, Maryam Ba-Break and Hülya Gül
    Citation: BMC Cancer 2024 24:695
    Content type: Research Published on:

  11. Continued smoking after a cancer diagnosis can be associated with lower treatment tolerance, poorer outcomes, and reduced quality of life compared to non-smoking cancer patients or to those who have quit. Yet ...

    Authors: Frederike Bokemeyer, Lisa Lebherz, Carsten Bokemeyer, Kathleen Gali, Holger Schulz and Christiane Bleich
    Citation: BMC Cancer 2024 24:693
    Content type: Research Published on:

  12. Gliomas are the deadliest malignant tumors of the adult central nervous system. We previously discovered that beta2-microglobulin (B2M) is abnormally upregulated in glioma tissues and that it exerts a range of...

    Authors: Zhen-Yuan Liu, Feng Tang, Jing Wang, Jin-Zhou Yang, Xi Chen, Ze-Fen Wang and Zhi-Qiang Li
    Citation: BMC Cancer 2024 24:692
    Content type: Research Published on:

  14. The prognostic value of multifocality in paediatric papillary thyroid carcinoma (PTC) patients remains a subject of debate. This study aimed to explore the clinical significance and prognostic value of multifo...

    Authors: Yuxiao Sun, Yihao Liu, Hongqiang Li, Yifeng Tang, Weihao Liu, Yifei Zhang and Detao Yin
    Citation: BMC Cancer 2024 24:690
    Content type: Research Published on:

  16. Multicenter non-small cell lung cancer (NSCLC) patient data is information-rich. However, its direct integration becomes exceptionally challenging due to constraints involving different healthcare organization...

    Authors: Yuan Liu, Jinzao Huang, Jyh-Cheng Chen, Wei Chen, Yuteng Pan and Jianfeng Qiu
    Citation: BMC Cancer 2024 24:688
    Content type: Research Published on:

  17. Background The methylation of SHOX2 and RASSF1A shows promise as a potential biomarker for the early screening of lung cancer, offering a solution to remedy the limitations of morphological diagnosis. The aim of ...

    Authors: Jiaping Zhao, Yu Lu, Xiaosha Ren, Tingting Bian, Jia Feng, Hui Sun, Lei Liu, Bin She, Yifei Liu and Honggang Ke
    Citation: BMC Cancer 2024 24:687
    Content type: Research Published on:

  18. Primary tracheal tumors are very rare and their management is not definitely established. Due to its rarity, providing patient care in terms of optimal management poses a considerable challenge. The purpose of...

    Authors: Aleksandra Piórek, Adam Płużański, Magdalena Knetki-Wróblewska, Kinga Winiarczyk, Sylwia Tabor, Paweł Teterycz, Dariusz M. Kowalski and Maciej Krzakowski
    Citation: BMC Cancer 2024 24:686
    Content type: Research Published on:

  19. Gastric cancer is one of the most common tumors worldwide, and most patients are deprived of treatment options when diagnosed at advanced stages. PRDM14 has carcinogenic potential in breast and non-small cell ...

    Authors: Xiao Li, Cong Wang, Youcai Wang, Xiaobing Chen, Zhi Li, Jianwei Wang and Yingjun Liu
    Citation: BMC Cancer 2024 24:685
    Content type: Research Published on:

  20. Many randomized controlled trials (RCTs) and network meta-analyses have demonstrated that the progression-free survival (PFS) and overall survival (OS) of advanced non-small cell lung cancer (NSCLC) patients c...

    Authors: Wen Hui, Wentan Li, Ruomeng Song, Yu Xin, Changjin Wu, Zhixiang Gao, Mingyue Zhang, Huazhang Wu, Min Zhu and Yuanyi Cai
    Citation: BMC Cancer 2024 24:684
    Content type: Research Published on:

  21. MicroRNAs (miRNAs) emerge in various organisms, ranging from viruses to humans, and play crucial regulatory roles within cells, participating in a variety of biological processes. In numerous prediction method...

    Authors: Hou Biyu, Li Mengshan, Hou Yuxin, Zeng Ming, Wang Nan and Guan Lixin
    Citation: BMC Cancer 2024 24:683
    Content type: Research Published on:

  23. Our previous studies have indicated that mRNA and protein levels of PPIH are significantly upregulated in Hepatocellular Carcinoma (LIHC) and could act as predictive biomarkers for patients with LIHC. Nonetheless...

    Authors: Jun Ye, Jianchao Ying, Haixia Chen, Zhiping Wu, Chaolin Huang, Chuan Zhang, Zhitao Chen and Haini Chen
    Citation: BMC Cancer 2024 24:681
    Content type: Research Published on:

  25. To evaluate the feasibility, safety and efficacy of concurrent simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) combined with nimotuzumab in the treatment of locally advanced esophagea...

    Authors: Lan Wang, Lihong Liu, Yu Cao, Xiaoxi Chen, Shutang Liu, Xiaoning Li, Jing Han, Qi Wang and Chun Han
    Citation: BMC Cancer 2024 24:679
    Content type: Research Published on:

  26. Despite several preventative and control measures Ethiopia continues to see an increase in cervical cancer. Comprehensive evidence is very important to suggest ministry of health. Therefore, the aim of this st...

    Authors: Yeshiwas Ayale Ferede, Worku Chekol Tassew and Agerie Mengistie Zeleke
    Citation: BMC Cancer 2024 24:678
    Content type: Systematic Review Published on:

  27. Mortality benefit of transfusion with leucoreduced whole blood has not been demonstrated in the sub-Saharan Africa (SSA). We compared mortality in patients with cancer transfused with leucoreduced and non-leuc...

    Authors: Clement D. Okello, Jackson Orem, Martin Nabwana, Noah Kiwanuka, Andrew W. Shih, Nancy Heddle and Harriet Mayanja-Kizza
    Citation: BMC Cancer 2024 24:677
    Content type: Research Published on:

  28. Circulating total insulin-like growth factor-I (IGF-I) is an established risk factor for prostate cancer. However, only a small proportion of circulating IGF-I is free or readily dissociable from IGF-binding p...

    Authors: Tuck Seng Cheng, Urwah Noor, Eleanor Watts, Michael Pollak, Ye Wang, James McKay, Joshua Atkins, Giovanna Masala, Maria-Jose Sánchez, Antonio Agudo, Jesús Castilla, Dagfinn Aune, Sandra M. Colorado-Yohar, Luca Manfredi, Marc J. Gunter, Valeria Pala…
    Citation: BMC Cancer 2024 24:676
    Content type: Research Published on:

  29. Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine tumour of the skin with poor prognosis and rising global incidence. A recently published article in BMC Cancer, titled “Merkel cell carcinoma...

    Authors: James Leigh and Kurt Gebauer
    Citation: BMC Cancer 2024 24:675
    Content type: Matters Arising Published on:

  30. Colorectal cancer is the leading cause of cancer death worldwide. The first and second lines of treatment for metastatic colorectal cancer (mCRC) include chemotherapy based on 5-fluorouracil. However, treatmen...

    Authors: Francisco Cezar Aquino de Moraes, Felipe Dircêu Dantas Leite Pessôa, Caio Henrique Duarte de Castro Ribeiro, Marianne Rodrigues Fernandes, Rommel Mario Rodríguez Burbano and Ney Pereira Carneiro dos Santos
    Citation: BMC Cancer 2024 24:674
    Content type: Research Published on:

  31. Hepatocellular carcinoma (HCC) genomic research has discovered actionable genetic changes that might guide treatment decisions and clinical trials. Nonetheless, due to a lack of large-scale multicenter clinica...

    Authors: Mengqi Song, Haoyue Cheng, Hao Zou, Kai Ma, Lianfang Lu, Qian Wei, Zejiang Xu, Zirui Tang, Yuanzheng Zhang, Yinan Wang and Chuandong Sun
    Citation: BMC Cancer 2024 24:673
    Content type: Research Published on:

  32. Patients with primary multifocal hepatocellular carcinoma (HCC) have a poor prognosis and often experience a high rate of treatment failure. Multifocal HCC is mainly caused by intrahepatic metastasis (IM), and...

    Authors: Weilong Zou, Zhanjie Fang, Yu Feng, Shangjin Gong, Ziqiang Li, Meng Li, Yong Sun, Xiuyan Ruan, Xiangdong Fang, Hongzhu Qu and Haiyang Li
    Citation: BMC Cancer 2024 24:672
    Content type: Research Published on:

  33. The role of novel circular RNAs (circRNAs) in colorectal cancer (CRC) remains to be determined. This study aimed to identify a novel circRNA involved in CRC pathogenesis, assess its diagnostic value, and const...

    Authors: Ke-zhi Li, Xiao-min Liao, Si-qi Li, Hao-tang Wei, Zhi-jian Liang, Liu-xin Ge, Su-fang Zhou and Bang-li Hu
    Citation: BMC Cancer 2024 24:671
    Content type: Research Published on:

  34. An accurate and non-invasive approach is urgently needed to distinguish tuberculosis granulomas from lung adenocarcinomas. This study aimed to develop and validate a nomogram based on contrast enhanced-compute...

    Authors: Liping Yang, Zhiyun Jiang, Jinlong Tong, Nan Li, Qing Dong and Kezheng Wang
    Citation: BMC Cancer 2024 24:670
    Content type: Research Published on:

  35. Cancer has become a major health concern due to the increasing morbidity and mortality rates, and its negative social, economic consequences and the heavy financial burden incurred by cancer patients. About 40...

    Authors: Mohamed Khalis, Imad Elbadisy, Oumnia Bouaddi, Amy Luo, Amina Bendriouich, Badr Addahri, Hafida Charaka, Mohamed Chahboune, Jérôme Foucaud, Abdallah Badou, Lahcen Belyamani and Inge Huybrechts
    Citation: BMC Cancer 2024 24:669
    Content type: Research Published on:

  36. Gastrointestinal cancers represent one of the most prevalent diseases worldwide. Strikingly, the incidence of Early Onset Gastrointestinal Cancer (EOGIC) has been rising during the last decades and changes in ...

    Authors: R. Vera, N. Castro, I. Labiano, A. Lecumberri, A. E. Huerta, H. Arasanz, I. Caseda, F. Ruiz-Pace, C. Viaplana, V. Arrazubi, I. Hernandez-Garcia, E. Mata, D. Gomez, S. Laguna, J. Suarez, I. Fernandez-De-los-Reyes…
    Citation: BMC Cancer 2024 24:668
    Content type: Study Protocol Published on:

    The Correction to this article has been published in BMC Cancer 2024 24:819

  37. The causal impact of lipid-lowering drugs on ovarian cancer (OC) and cervical cancer (CC) has received considerable attention, but its causal relationship is still a subject of debate. Hence, the objective of ...

    Authors: Jinshuai Li, Zixian Yang, Tao Wang, Mengqi Li, Xiangjian Wu, Xiaoyan Fu, Chunfeng Yang, Yangpu Li, Ximing Wang, Zhiming Lan, Minfang Li and Sheng Chen
    Citation: BMC Cancer 2024 24:667
    Content type: Research Published on:

  38. Currently, there is no consensus on the treatment of recurrent hepatocellular carcinoma (HCC) after hepatectomy. It is necessary to assess the efficacy and safety of radiofrequency ablation (RFA) combined with...

    Authors: Fei Cao, Jiaping Zheng and Weiyuan Hao
    Citation: BMC Cancer 2024 24:666
    Content type: Research Published on:

  40. Recent studies have shown that blue light-emitting diode (LED) light has anti-tumor effects, suggesting the possibility of using visible light in cancer therapy. However, the effects of blue light irradiation ...

    Authors: Toshiaki Yoshimoto, Masaaki Nishi, Shohei Okikawa, Kozo Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Yuma Wada, Takayuki Noma and Mitsuo Shimada
    Citation: BMC Cancer 2024 24:664
    Content type: Research Published on:

  41. Death anxiety is thought to cause a range of mental disorders among cancer patients, which may affect their mental health and even quality of life. This study sought to investigate experiential avoidance, mean...

    Authors: Yixia Yan, Yongyi Chen, Meijun Ou, Youwen Gong, Renting Yang, Xiangyu Liu, Wanting Xia, Furong Chen, Hongling Zheng and Xianghua Xu
    Citation: BMC Cancer 2024 24:663
    Content type: Research Published on:

  42. Despite increased use of immune checkpoint inhibitors (ICIs) in patients with advanced melanoma, little is known about patient experiences during this treatment. This study aimed to gain an in-depth understand...

    Authors: Nadia C.W. Kamminga, Astrid A.M. van der Veldt, Marlies Wakkee, Fauve R. van den Berge, Lianne A.A. van der Beek, Margot C.W. Joosen, Arjen Joosse, Karlijn de Joode, Tamar E.C. Nijsten and Marjolein Lugtenberg
    Citation: BMC Cancer 2024 24:662
    Content type: Research Published on:

  43. In the era of targeted therapies, the influence of aging on cancer management varies from one patient to another. Assessing individual frailty using geriatric tools has its limitations, and is not appropriate ...

    Authors: Mélanie Casile, Gilles Albrand, Clément Lahaye, Benjamin Lebecque, Joévin Besombes, Céline Bourgne, Bruno Pereira, Sandrine Saugues, Caroline Jamot, Eric Hermet and Marc G. Berger
    Citation: BMC Cancer 2024 24:661
    Content type: Study Protocol Published on:

    The Correction to this article has been published in BMC Cancer 2024 24:806

  44. Breast and cervical cancer are the two leading cancers in terms of incidence and mortality. Previous studies reported different interleukins, including interleukin-17A (IL-17A) to be responsible for the developme...

    Authors: Md. Abdul Aziz, Subrina Chowdhury, Sarah Jafrin, Md Abdul Barek, Mohammad Sarowar Uddin, Md. Shalahuddin Millat and Mohammad Safiqul Islam
    Citation: BMC Cancer 2024 24:660
    Content type: Research Published on:

  45. To investigate the diagnostic efficacy of high-frame-rate contrast-enhanced ultrasound (H-CEUS) in differentiating between clear cell renal cell carcinoma (CCRCC) and angiomyolipoma (AML).

    Authors: JingLing Wang, JiaYu Shi, Long Gao, WeiHong Hu, Miao Chen and WeiPing Zhang
    Citation: BMC Cancer 2024 24:659
    Content type: Research Published on:

  46. Adherence to chemotherapy treatment is recognized as a crucial health concern, especially in managing cancer patients. Chemotherapy presents challenges for patients, as it can lead to potential side effects th...

    Authors: Amineh Rashidi, Susma Thapa, Wasana Sandamali Kahawaththa Palliya Guruge and Shubhpreet Kaur
    Citation: BMC Cancer 2024 24:658
    Content type: Systematic Review Published on:

  47. This study aims to compare treatment outcomes between neoadjuvant chemotherapy (NACT) followed by surgery and concurrent chemoradiotherapy (CCRT) in patients with stage IIB cervical squamous cell carcinoma (CS...

    Authors: Xin-Bin Pan, Yan Lu, You-Sheng Wei and De-Sheng Yao
    Citation: BMC Cancer 2024 24:655
    Content type: Research Published on:

  48. Immune checkpoint inhibitors (ICIs) have demonstrated superior clinical efficacy in prolonging overall survival (OS) as the second-line treatment for advanced or metastatic esophageal squamous cell carcinoma (...

    Authors: Xiuli Yang, Xiaochun Zheng, Sang Hu, Jinlong Huang, Miaomiao Zhang, Ping Huang and Jiangfeng Wang
    Citation: BMC Cancer 2024 24:654
    Content type: Research Published on:

  49. Pancreatic cancer, a highly fatal malignancy, has shown a global rise in the incidence and mortality rates. However, these rates vary significantly across different regions worldwide. This study aims to assess...

    Authors: Nasr Eldin Elwali, Saad Mohammed AlShareef, Ammar H. Khamis and Moawia M. A. Elhassan
    Citation: BMC Cancer 2024 24:653
    Content type: Research Published on:

  50. Pancreatic ductal adenocarcinoma (PDAC) ranks among the deadliest types of cancer, and it will be meaningful to search for new biomarkers with prognostic value to help clinicians tailor therapeutic strategies.

    Authors: Xiwen Chen, Linying Chen, Jikui Miao, Xingxin Huang, Xiahui Han, Liqin Zheng, Shuoyu Xu, Jianxin Chen and Lianhuang Li
    Citation: BMC Cancer 2024 24:652
    Content type: Research Published on:

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