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Featured article: Early cancer detection - Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of cfDNA

Blood-based methods using cell-free DNA (cfDNA) are under development as an alternative to existing screening tests. However, detection of cancer using tumor-derived cfDNA has proven challenging. Here Dr. Putcha et al. show that a machine learning approach using cfDNA achieved high sensitivity and specificity in a large, early-stage, colorectal cancer cohort.

Blood Cancer Awareness Month September

New Content ItemTo mark blood cancer awareness month the BMC Editors have carefully curated a collection of open access articles on this topic and there is an awareness quiz to test your blood cancer knowledge.

We are delighted to present a collection of all the cancer awareness campaigns completed in 2019. New content will be uploaded on a monthly basis.

Join our Editorial Board

​​​​​​​New Content Item (4)

We are now recruiting Associate Editors for our Editorial Board to join our team of academic editors in assessing manuscripts in the field of cancer research. Diversity in all forms will be a driving factor when selecting an individual to serve in this capacity. Please find more information and the application form here.

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Featured review: Gallbladder cancer: review of a rare orphan gastrointestinal cancer with a focus on populations of New Mexico

Gallbladder cancer is a rare malignancy of the biliary tract with a poor prognosis, frequently presenting at an advanced stage. While rare in the United States overall, gallbladder cancer has an elevated incidence in geographically distinct locations of the globe including Chile, North India, Korea, Japan and the state of New Mexico in the United States. Rama R. Gullapalli, Associate Editor for BMC Cancer provides this review.

Featured video: Microparticles, breast cancer's secret weapon?

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Featured review: A stepwise approach to constructing systematic reviews

New Content ItemSystematic reviews, with or without meta-analysis, play an important role today in synthesizing cancer research and are frequently used to guide decision-making. With a focus on cancer, first author, Prof Kelley, provides a practical, stepwise approach for systematically reviewing the literature and publishing the results. 

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Featured article: SABR-COMET-10: Study protocol for a randomized Phase III Trial

Stereotactic ablative radiotherapy (SABR) has emerged as a new treatment option for patients with oligometastatic disease. David Palma, Robert Olson and colleagues recently found that SABR was associated with benefits in progression-free survival and overall survival in the Phase II Trial. The goal of this international, Phase III Trial is to assess the impact of SABR in patients with 4–10 metastatic cancer lesions.

Aims and scope

BMC Cancer is an open access, peer-reviewed journal that considers articles on all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials.

Journal Sections

Cross-journal thematic series: Precision Oncology

We are proud to finally present the publications from our cross-journal thematic series, Precision Oncology. This collection focuses on how precision oncology has shaped advances in the impact of non-coding RNAs in epigenetics and cancer, immunotherapy and tumor biology. Also of note are the technological developments for preclinical routines and the clinical significance of various therapies in breast, esophageal, liver, lung, ovarian cancers, among other types.

Trending BMC Cancer Articles

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Editor
Linda Gummlich, BMC Series, London, UK

Assistant Editors

Catherine Rice, Senior Assistant Editor, BMC Series, London
William Spenceley Jones, Assistant Editor, BMC Series, London

Consulting Editors
Yanis BoumberFox Chase Cancer Center, USA
Ken Herrmann, Universitätsklinikum Essen, Germany
Alan Lefor, Jichi Medical University, Japan
Christophe Nicot, Kansas University Medical Center, USA
Stephen Povoski, The Ohio State University, USA
Dirk Vordermark, Martin Luther University Halle-Wittenberg, Germany

Editorial: Nobel Prize Cancer Immunotherapy!

Follow Nobel Prize laureates James P. Allison's and Tasuku Honjo's footsteps and experience the genesis of a new field of cancer therapy. BMC Cancer Editorial Board Member Dr. Sheng Guo from Pittsburgh University takes us on an exciting journey of discovery...

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