BMC Cancer

Extracellular vesicles in cancer progression

Guest Edited by: Orazio Fortunato, Irina Matei and Chunlin Ou

Characterization and comparison of human glioblastoma models

Schulz et al. characterized two human GBM models (U87-luc2, U251-RedFLuc) in vitro and in vivo, showing that they recapitulate different aspects of GBM heterogeneity that need to be considered in preclinical research.

Phantom-based acquisition time and image reconstruction parameter optimisation for oncologic FDG PET/CT examinations using a digital system

Fragoso Costa et al. determined the lowest ¹⁸F-FDG PET acquisition time without loss of diagnostic information and optimised image reconstruction parameters by phantom imaging.

Inhibition of hyperprogressive cancer disease induced by immune-checkpoint blockade upon co-treatment with meta-tyrosine and p38 pathway inhibitor

Montagna et al. investigated the hyperprogressive-cancer disease in two murine tumors widely different regarding immunogenicity and in models of local recurrences and metastases. 

BMC Cancer is an open access, peer-reviewed journal that considers articles on all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions in broad areas of cancer research including molecular and cellular biology, genetics, epidemiology, and clinical trials. Learn more about our scope here. 

Childhood Cancer awareness month runs for the whole of September. While childhood cancer is rare, it is the leading cause of disease-related death past infancy in children and adolescents. Survival rates for most childhood cancers have improved in recent decades, however many children will have long-term side-effects that may significantly impact their lives forever. In the paper below Masumoto et al. reported game-based learning programs as tools that can be effectively applied to survivorship care as a new modality of patient education.

A pilot study of game-based learning programs for childhood cancer survivors

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