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  1. Research article

    Cost-effectiveness analysis of XELOX versus XELOX plus bevacizumab for metastatic colorectal cancer in a public hospital school

    Metastatic colorectal cancer imposes a substantial burden on patients and society. Over the last years, progresses in the treatment have been made especially due to the introduction of monoclonal antibodies, s...

    Andrea Queiróz Ungari, Leonardo Régis Leira Pereira, Altacílio Aparecido Nunes and Fernanda Maris Peria

    BMC Cancer 2017 17:691

    Published on: 17 October 2017

  2. Research article

    Societal preferences for adjuvant melanoma health states: UK and Australia

    No studies have measured preference-based utility weights for specific toxicities and outcomes associated with approved and investigational adjuvant treatments for patients with resected high-risk melanoma.

    Mark R. Middleton, Michael B. Atkins, Kaitlan Amos, Peter Feng Wang, Srividya Kotapati, Javier Sabater and Kathleen Beusterien

    BMC Cancer 2017 17:689

    Published on: 17 October 2017

  3. Research article

    Personalized treatment of women with early breast cancer: a risk-group specific cost-effectiveness analysis of adjuvant chemotherapy accounting for companion prognostic tests OncotypeDX and Adjuvant!Online

    Due to high survival rates and the relatively small benefit of adjuvant therapy, the application of personalized medicine (PM) through risk stratification is particularly beneficial in early breast cancer (BC)...

    Beate Jahn, Ursula Rochau, Christina Kurzthaler, Michael Hubalek, Rebecca Miksad, Gaby Sroczynski, Mike Paulden, Marvin Bundo, David Stenehjem, Diana Brixner, Murray Krahn and Uwe Siebert

    BMC Cancer 2017 17:685

    Published on: 16 October 2017

  4. Research article

    Epidemiology of cervical human papillomavirus (HPV) infection and squamous intraepithelial lesions (SIL) among a cohort of HIV-infected and uninfected Ghanaian women

    There is limited data in Ghana on the epidemiology of HPV and cervical neoplasia and their associations with HIV. This study aimed to compare among HIV-1 seropositive and HIV-seronegative Ghanaian women: (1) t...

    Dorcas Obiri-Yeboah, Patrick K. Akakpo, Mohamed Mutocheluh, Emmanuel Adjei-Danso, Gloria Allornuvor, Daniel Amoako-Sakyi, Yaw Adu-Sarkodie and Philippe Mayaud

    BMC Cancer 2017 17:688

    Published on: 16 October 2017

  5. Research article

    Methodological study to evaluate the psychometric properties of FACIT-CD in a sample of Brazilian women with cervical intraepithelial neoplasia

    The occurrence of cervical intraepithelial neoplasia (CIN) is associated with changes in health-related quality of life, including psychological factors, such as fear and shame, and changes in sexuality and se...

    Cristiane Menezes Sirna Fregnani, José Humberto Tavares Guerreiro Fregnani and Adhemar Longatto-Filho

    BMC Cancer 2017 17:686

    Published on: 16 October 2017

  6. Research article

    The association between high birth weight and the risks of childhood CNS tumors and leukemia: an analysis of a US case-control study in an epidemiological database

    High birth weight (BW), 4000 g or larger, is an established risk factor for childhood leukemia. However, its association with central nervous system (CNS) tumor risk is yet unclear. The present study examined ...

    Long Thanh Tran, Hang Thi Minh Lai, Chihaya Koriyama, Futoshi Uwatoko and Suminori Akiba

    BMC Cancer 2017 17:687

    Published on: 16 October 2017

  7. Research article

    A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice

    Cytotoxic chemotherapeutics form the cornerstone of systemic treatment of many cancers. Patients are dosed at maximum tolerated dose (MTD), which is carefully determined in phase I studies. In contrast, in mur...

    Wayne J. Aston, Danika E. Hope, Anna K. Nowak, Bruce W. Robinson, Richard A. Lake and W. Joost Lesterhuis

    BMC Cancer 2017 17:684

    Published on: 16 October 2017

  8. Research article

    Cancer incidence in Germany attributable to human papillomavirus in 2013

    It is estimated that a total of 120,000 new cancer cases in men and in women in more developed countries could be avoided if exposure to HPV was prevented. We used the nationwide pool of German population-base...

    Nina Buttmann-Schweiger, Yvonne Deleré, Stefanie J. Klug and Klaus Kraywinkel

    BMC Cancer 2017 17:682

    Published on: 16 October 2017

  9. Research article

    A single-arm phase II study of nab-paclitaxel for patients with chemorefractory non-small cell lung cancer

    We aimed to evaluate the efficacy and safety of nab-paclitaxel in patients with refractory advanced non-small cell lung cancer who failed previous chemotherapy.

    Hisashi Tanaka, Kageaki Taima, Takeshi Morimoto, Yoshihito Tanaka, Masamichi Itoga, Kunihiko Nakamura, Akihito Hayashi, Mika Kumagai, Hideo Yasugahira, Megumi Mikuniya, Koichi Okudera, Shingo Takanashi and Sadatomo Tasaka

    BMC Cancer 2017 17:683

    Published on: 16 October 2017

  10. Research article

    Higher educational attainment associated with reduced likelihood of abnormal cervical lesions among Zambian women - a cross sectional study

    The high burden of cervical cancer in Zambia prompted the Ministry of Health and partners to develop the cervical cancer prevention program in Zambia (CCPPZ) in 2006. Despite this intervention more women conti...

    Twaambo Euphemia Hamoonga, Rosemary Ndonyo Likwa, Patrick Musonda and Charles Michelo

    BMC Cancer 2017 17:681

    Published on: 13 October 2017

  11. Research article

    The prognostic value of pretreatment tumor apparent diffusion coefficient values in nasopharyngeal carcinoma

    Diffusion-weighted MR imaging (DWI) has increasingly contributed to the management of nasopharyngeal carcinoma (NPC) patients. The objective of this paper was to explore the prognostic significance of apparent...

    Dan-Fang Yan, Wen-Bao Zhang, Shan-Bao Ke, Feng Zhao, Sen-Xiang Yan, Qi-Dong Wang and Li-Song Teng

    BMC Cancer 2017 17:678

    Published on: 11 October 2017

  12. Research article

    The XRCC 1 DNA repair gene modifies the environmental risk of stomach cancer: a hospital-based matched case-control study

    Previous studies have found that polymorphisms of the DNA repair gene X-ray repair cross-complementing group 1(XRCC1) and environmental factors are both associated with an increased risk of stomach cancer, but no...

    Nuntiput Putthanachote, Supannee Promthet, Cameron Hurst, Krittika Suwanrungruang, Peechanika Chopjitt, Surapon Wiangnon, Sam Li-Sheng Chen, Amy Ming-Fang Yen and Tony Hsiu-Hsi Chen

    BMC Cancer 2017 17:680

    Published on: 11 October 2017

  13. Study protocol

    Enzalutamide versus abiraterone as a first-line endocrine therapy for castration-resistant prostate cancer (ENABLE study for PCa): a study protocol for a multicenter randomized phase III trial

    Both enzalutamide and abiraterone have demonstrated improved radiographic progression-free and overall survival for castration-resistant prostate cancer (CRPC) compared with placebo controls before docetaxel t...

    Kouji Izumi, Atsushi Mizokami, Mikio Namiki, Shogo Inoue, Nobumichi Tanaka, Yuko Yoshio, Kei Ishibashi, Manabu Kamiyama, Noriyasu Kawai, Hideki Enokida, Takashi Shima and Shizuko Takahara

    BMC Cancer 2017 17:677

    Published on: 10 October 2017

  14. Research article

    Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin

    Cutaneous basal cell carcinoma (BCC) is the commonest cancer worldwide. BCC is locally invasive and the surrounding stromal microenvironment is pivotal for tumourigenesis. Cancer associated fibroblasts (CAFs) ...

    Silje Haukali Omland, Erika Elgstrand Wettergren, Tobias Mourier, Anders Johannes Hansen, Maria Asplund, Sarah Mollerup and Robert Robert

    BMC Cancer 2017 17:675

    Published on: 7 October 2017

  15. Study protocol

    Selection of opioids for cancer-related pain using a biomarker: a randomized, multi-institutional, open-label trial (RELIEF study)

    Cancer patients experience pain that has physiological, sensory, affective, cognitive, behavioral, and sociocultural dimensions. Opioids are used in treatment of pain in patients with various types of cancer. ...

    Hiromichi Matsuoka, Junji Tsurutani, Yasutaka Chiba, Yoshihiko Fujita, Masato Terashima, Takeshi Yoshida, Kiyohiro Sakai, Yoichi Otake, Atsuko Koyama, Kazuto Nishio and Kazuhiko Nakagawa

    BMC Cancer 2017 17:674

    Published on: 6 October 2017

  16. Research article

    Respiratory-gated (4D) contrast-enhanced FDG PET-CT for radiotherapy planning of lower oesophageal carcinoma: feasibility and impact on planning target volume

    To assess the feasibility and potential impact on target delineation of respiratory-gated (4D) contrast-enhanced 18Fluorine fluorodeoxyglucose (FDG) positron emission tomography - computed tomography (PET-CT), in...

    Andrew Scarsbrook, Gillian Ward, Patrick Murray, Rebecca Goody, Karen Marshall, Garry McDermott, Robin Prestwich and Ganesh Radhakrishna

    BMC Cancer 2017 17:671

    Published on: 4 October 2017

  17. Research article

    MiR-216b inhibits cell proliferation by targeting FOXM1 in cervical cancer cells and is associated with better prognosis

    Our previous study showed FOXM1 expression was significantly up-regulated in cervical cancer, and was associated with poor prognosis. To clarify miRNAs-FOXM1 modulation pathways, in this study, we investigated...

    Shanyang He, Bing Liao, Yalan Deng, Chang Su, Jiuling Tuo, Jun Liu, Shuzhong Yao and Lin Xu

    BMC Cancer 2017 17:673

    Published on: 4 October 2017

  18. Research article

    Evaluation of Slug expression is useful for predicting lymph node metastasis and survival in patients with gastric cancer

    Slug is a transcription factor that activates the epithelial–mesenchymal transition (EMT) process in cancer progression. The aim of our study was to evaluate the clinical significance ...

    Han Hee Lee, Sung Hak Lee, Kyo Young Song, Sae Jung Na, Joo Hyun O, Jae Myung Park, Eun Sun Jung, Myung-Gyu Choi and Cho Hyun Park

    BMC Cancer 2017 17:670

    Published on: 3 October 2017

  19. Correction

    BMC Cancer 2017 17:667

    Published on: 2 October 2017

    The original article was published in BMC Cancer 2017 17:193

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