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  1. Traditional nanodrug delivery systems have some limitations, such as eliciting immune responses and inaccuracy in targeting tumor microenvironments.

    Authors: Xuanbo Da, Bangping Cao, Jiantao Mo, Yukai Xiang, Hai Hu, Chen Qiu, Cheng Zhang, Beining Lv, Honglei Zhang, Chuanqi He and Yulong Yang
    Citation: BMC Cancer 2024 24:273
  2. Chemotherapy for metastatic pancreatic adenocarcinoma (PDAC) primarily relies on FOLFIRINOX (LV5FU- irinotecan – Oxaliplatine) and Gemcitabine – Nab-Paclitaxel in the first-line setting. However, second-lines ...

    Authors: A. Gueiderikh, A. Tarabay, M. Abdelouahab, C. Smolenschi, M. L. Tanguy, M. Valery, D. Malka, T. Pudlarz, A. Fuerea, V. Boige, A. Hollebecque, M. Ducreux and A. Boilève
    Citation: BMC Cancer 2024 24:272
  3. Previous studies have observed a link between immunophenotypes and lung cancer, both of which are closely associated with genetic factors. However, the causal relationship between them remains unclear.

    Authors: Ming Xu, Chengkai Li, Liyan Xiang, Siyue Chen, Lin Chen, Gongxia Ling, Yanqing Hu, Lan Yang, Xiang Yuan, Xiaodong Xia and Hailin Zhang
    Citation: BMC Cancer 2024 24:270
  4. Immune checkpoint inhibitors (ICIs) can lead to life-threatening pneumonitis, and pre-existing interstitial lung abnormalities (ILAs) are a risk factor for checkpoint inhibitor pneumonitis (CIP). However, the ...

    Authors: Xinyue Wang, Jinkun Zhao, Ting Mei, Wenting Liu, Xiuqiong Chen, Jingya Wang, Richeng Jiang, Zhaoxiang Ye and Dingzhi Huang
    Citation: BMC Cancer 2024 24:269
  5. Gemcitabine is a cornerstone drug for the treatment of all stages of pancreatic cancer and can prolong the survival of patients with pancreatic cancer, but resistance to gemcitabine in pancreatic cancer patien...

    Authors: Zhe Yang, Feiran Chen, Dafu Wei, Fengping Chen, Haixing Jiang and Shanyu Qin
    Citation: BMC Cancer 2024 24:268
  6. Significant advancements in improving ovarian cancer (OC) outcomes have been limited over the past decade. To predict prognosis and improve outcomes of OC, we plan to develop and validate a robust prognosis si...

    Authors: Meixuan Wu, Sijia Gu, Jiani Yang, Yaqian Zhao, Jindan Sheng, Shanshan Cheng, Shilin Xu, Yongsong Wu, Mingjun Ma, Xiaomei Luo, Hao Zhang, Yu Wang and Aimin Zhao
    Citation: BMC Cancer 2024 24:267
  7. Immune checkpoint inhibitors (ICIs) are commonly used in conjunction with chemotherapy to improve treatment outcomes for patients with gastric cancer. Since AFP could influence immunity by both inhibiting natu...

    Authors: Jingjing Zhang, Lei Wang, Shasha Zhang, Ruijie Cao, Yufei Zhao, Yue Zhao, Yanrong Song and Zhanjun Guo
    Citation: BMC Cancer 2024 24:266
  8. To evaluate the safety and effectiveness of computed tomography (CT)-guided radioactive 125I seeds brachytherapy (RISB) for lung oligometastases (LO) from colorectal cancer (CRC).

    Authors: Mengyao Song, Xueliang Zhou, Rongna Hou, Milan Sigdel, Yiming Liu, Chengzhi Zhang, Kaihao Xu, Xinwei Han and Dechao Jiao
    Citation: BMC Cancer 2024 24:265
  9. Patients with advanced gastrointestinal stromal tumors (GISTs) exhibiting an imatinib plasma trough concentration (IM Cmin) under 1100 ng/ml may show a reduced drug response rate, leading to the suggestion of mon...

    Authors: Pan Ran, Tao Tan, Jinjin Li, Hao Yang, Juan Li and Jun Zhang
    Citation: BMC Cancer 2024 24:264
  10. Whether Transanal drainage tubes (TDTs) placement reduces the occurrence of anastomotic leakage (AL) after rectal cancer (RC) surgery remains controversial. Most existing meta-analyses rely on retrospective st...

    Authors: Yating Liu, Xuhua Hu, Yu Huang, Xu Yin, Pengfei Zhang, Yaoguang Hao, Hongyan Li and Guiying Wang
    Citation: BMC Cancer 2024 24:263
  11. Advanced pancreatic cancer is one of the leading causes of cancer-related deaths. For patients with advanced pancreatic cancer, gemcitabine and nanoparticle albumin-binding paclitaxel (nabPTX) combination (GEM...

    Authors: Hiroo Imai, Yasuhiro Sakamoto, Shin Takahashi, Hiroyuki Shibata, Atsushi Sato, Kazunori Otsuka, Kenji Amagai, Masanobu Takahashi, Takuhiro Yamaguchi and Chikashi Ishioka
    Citation: BMC Cancer 2024 24:262
  12. Increasing evidence indicates that gut microbiota are closely related to prostate cancer. This study aims to assess the gut microbiota composition in patients with prostate cancer compared to healthy participa...

    Authors: Haotian Huang, Yang Liu, Zhi Wen, Caixia Chen, Chongjian Wang, Hongyuan Li and Xuesong Yang
    Citation: BMC Cancer 2024 24:261
  13. Primary tumor removal by cytoreductive nephrectomy in synchronous metastatic renal cell carcinoma patients has been investigated in the context of various treatment regimens. Two randomized controlled trials i...

    Authors: Laura Iisager, Johanne Ahrenfeldt, Frede Donskov, Börje Ljungberg, Axel Bex, Lars Lund, Iben Lyskjær and Niels Fristrup
    Citation: BMC Cancer 2024 24:260
  14. For cervical cancer (CC), the implementation of preventive strategies has the potential to make cervical cancer occurrence and death largely avoidable. To better understand the factors possibly responsible for...

    Authors: Sara Bønløkke, Jan Blaakær, Torben Steiniche and Maria Iachina
    Citation: BMC Cancer 2024 24:259
  15. CCRT is presently the standard treatment for LA-NSCLC. RP is one of the main obstacles to the completion of thoracic radiation therapy, resulting in limited survival benefits in NSCLC patients. This research a...

    Authors: Kuifei Chen, Shuling Li, Meng Chen, Zhicheng Jin, Xuefeng Sun, Suna Zhou and Haihua Yang
    Citation: BMC Cancer 2024 24:257
  16. The low specificity of Thyroid Imaging Reporting and Data System (TI-RADS) for preoperative benign-malignant diagnosis leads to a large number of unnecessary biopsies. This study developed and validated a pred...

    Authors: Tingting Zheng, Lanyun Wang, Hao Wang, Lang Tang, Xiaoli Xie, Qingyin Fu, Pu-Yeh Wu and Bin Song
    Citation: BMC Cancer 2024 24:256
  17. This study assesses the metastasis rate of the key distal lymph nodes (KDLN) that are not routinely dissected in proximal gastrectomy, aiming to explore the oncological safety of proximal gastrectomy for upper...

    Authors: Yonghe Chen, Xiaojiang Chen, Yi Lin, Shenyan Zhang, Zhiwei Zhou and Junsheng Peng
    Citation: BMC Cancer 2024 24:255
  18. The purpose of this study was to develop a functional clinical nomogram for predicting 8-year overall survival (OS) of patients with prostate cancer (PCa) primary based on peripheral lymphocyte.

    Authors: Jiayi Chen, Feng Yu, Ganyuan He, Wenke Hao and Wenxue Hu
    Citation: BMC Cancer 2024 24:254
  19. Cancer cachexia is associated with impaired functional and nutritional status and worse clinical outcomes. Global Leadership Initiative in Malnutrition (GLIM) consensus recommended the application of GLIM crit...

    Authors: Zong-Ze Li, Xia-Lin Yan, Zhao Zhang, Jiong-Lai Chen, Jiang-Yuan Li, Jing-Xia Bao, Jia-Tong Ru, Jia-Xin Wang, Xiao-Lei Chen, Xian Shen and Dong-Dong Huang
    Citation: BMC Cancer 2024 24:253
  20. Immune checkpoint inhibitor (ICI) or irinotecan-based chemotherapy is frequently used after failure of second-line paclitaxel plus ramucirumab treatment for patients with locally advanced unresectable or metas...

    Authors: Sung Hee Lim, Keun-Wook Lee, Jae-Joon Kim, Hyeon-Su Im, In-Ho Kim, Hye Sook Han, Dong-Hoe Koo, Jang Ho Cho, Chi Hoon Maeng, Min-Young Lee, Hyo Jin Lee, Jwa Hoon Kim, Sang Gon Park, Joo Young Jung, Seong-Hoon Shin, Ki Hyang Kim…
    Citation: BMC Cancer 2024 24:252
  21. The occurrence of surgical site infection (SSI) after pancreaticoduodenectomy (PD) is still relatively high. The aim of this retrospective study is to evaluate the efficacy of piperacillin-tazobactam as periop...

    Authors: Yifei Yang, Jianjie Sheng, Zhenghua Cai, Linxi Zhu, Chenglin Lu, Liang Mao, Yudong Qiu and Xu Fu
    Citation: BMC Cancer 2024 24:251
  22. Increasing evidence has showed that inflammatory biomarkers, including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and fibrinogen can be used as predictors in the prognosis of esop...

    Authors: Yuchong Yang, Hui Tan, Yao Lu, Jipeng Mei, Mengqi Zhang, Ming Bai, Xia Wang, Shaohua Ge, Tao Ning, Le Zhang, Zhi Ji, Jingjing Duan, Yansha Sun, Feixue Wang, Rui Liu, Hongli Li…
    Citation: BMC Cancer 2024 24:249
  23. Lung cancer is a leading cause of cancer-related mortality worldwide, and effective therapies are limited. Lung cancer is a leading cause of cancer-related mortality worldwide with limited effective therapy. S...

    Authors: Huang-Chi Chen, Chia-Yu Kuo, Yu Chang, Dong-Lin Tsai, Mei-Hsuan Lee, Jui-Ying Lee, Hui-Ming Lee and Yu-Chieh Su
    Citation: BMC Cancer 2024 24:248
  24. Limited information is available for guiding the management of upper urinary tract (UUT) urothelial carcinoma with squamous differentiation (UC-SqD). We did not even know about the difference between pure uro...

    Authors: Li-Hua Huang, Chuan-Shu Chen, Jian-Ri Li, Kun-Yuan Chiu, Shian-Shiang Wang, Cheng-Kuang Yang, Chen-Li Cheng, Chi-Chien Lin and Yen-Chuan Ou
    Citation: BMC Cancer 2024 24:247
  25. Artificial intelligence (AI)-assisted clinical trial screening is a promising prospect, although previous matching systems were developed in English, and relevant studies have only been conducted in Western co...

    Authors: Kunyuan Wang, Hao Cui, Yun Zhu, Xiaoyun Hu, Chang Hong, Yabing Guo, Lingyao An, Qi Zhang and Li Liu
    Citation: BMC Cancer 2024 24:246
  26. Esophageal squamous cell carcinoma (ESCC) is a high-risk malignant tumor that has been reported in China. Some studies indicate that gut microbiota disorders can affect the occurrence and development of ESCC, ...

    Authors: Xingqiang Huang, Xueyi Chen, Guowei Wan, Dandan Yang, Dongqiang Zhu, Linqian Jia and Jinping Zheng
    Citation: BMC Cancer 2024 24:245
  27. Identifying risk factors for adverse pathologic features in low-risk papillary thyroid microcarcinoma (PTMC) can provide valuable insights into the necessity of surgical or non-surgical treatment. This study a...

    Authors: Lei Gong, Ping Li, Jingjing Liu, Yan Liu, Xinghong Guo, Weili Liang, Bin Lv, Peng Su and Kai Liang
    Citation: BMC Cancer 2024 24:244
  28. Women living with HIV are at risk for cervical dysplasia and cancer worldwide. In 2015, the World Health Organization (WHO) recommended that testing for high-risk HPV (hrHPV) infection be incorporated into cer...

    Authors: Harriet Nakigozi, Rawlance Ndejjo, William Bazeyo, Annet Nabaggala, Caroline Achola, Moses Iga, Simeon Kalyesubula, Ben Kanamwangi, Gerald Mutungi, Charles Batte, David Mukunya, Lawrence Sserwanga, Godfrey Gemageine, Charles Akiya Oyoo and Susan Nabadda
    Citation: BMC Cancer 2024 24:243
  29. To explore the association between preoperative WBC count and the long-term survival outcomes and clinical outcomes in different stage patients who underwent surgical resection for colorectal cancer (CRC).

    Authors: Bei Wang, Dandan Ling, Lihong Li, Jun Zhang and Jianghui Xu
    Citation: BMC Cancer 2024 24:242
  30. The benefit of adding Zolbetuximab to the treatment in patients with Claudin-18 isoform 2 (CLDN18.2)-positive, human epidermal growth factor receptor 2-negative, locally advanced unresectable or metastatic gas...

    Authors: Francisco Cezar Aquino de Moraes, Eric Pasqualotto, Matheus Pedrotti Chavez, Rafael Oliva Morgado Ferreira, Tiago Biachi De Castria and Rommel Mario Rodríguez Burbano
    Citation: BMC Cancer 2024 24:240
  31. Hepatocellular carcinoma (HCC) is a common malignant tumor with strong invasiveness and poor prognosis. Previous studies have demonstrated the significant role of USP14 in various solid tumors. However, the ro...

    Authors: Nannan Zhang, Hui Zhang, Xiaobing Yang, Qiang Xue, Quhui Wang, Renan Chang, Lirong Zhu, Zhong Chen and Xiancheng Liu
    Citation: BMC Cancer 2024 24:237
  32. Peroxisome proliferator-activated receptor gamma (PPARG) is a member of the nuclear receptor family. It is involved in the regulation of adipogenesis, lipid metabolism, insulin sensitivity, vascular homeostasi...

    Authors: Leah Schöckel, Christine Woischke, Sai Agash Surendran, Marlies Michl, Tobias Schiergens, Andreas Hölscher, Florian Glass, Peter Kreissl, Frederick Klauschen, Michael Günther, Steffen Ormanns and Jens Neumann
    Citation: BMC Cancer 2024 24:234
  33. Head and neck squamous cell carcinoma (HNSCC) constitutes one of the most common types of human cancers and often metastasizes to lymph nodes. Platinum-based chemotherapeutic drugs are commonly used for treatm...

    Authors: Abdulkader Yassin-Kassab, Suman Chatterjee, Nayel Khan, Nathaniel Wang, Vlad C. Sandulache, Eric H-B. Huang, Timothy F. Burns and Umamaheswar Duvvuri
    Citation: BMC Cancer 2024 24:233
  34. Minimally invasive distal pancreatectomy (MIDP), including laparoscopic and robotic distal pancreatectomy, has gained widespread acceptance over the last decade owing to its favorable short-term outcomes. Howe...

    Authors: Naoki Ikenaga, Tadayoshi Hashimoto, Junki Mizusawa, Ryo Kitabayashi, Yusuke Sano, Haruhiko Fukuda, Kohei Nakata, Kazuto Shibuya, Yuji Kitahata, Minoru Takada, Keiko Kamei, Hiroshi Kurahara, Daisuke Ban, Shogo Kobayashi, Hiroaki Nagano, Hajime Imamura…
    Citation: BMC Cancer 2024 24:231
  35. This study aimed to identify metabolic subtypes in ESCA, explore their relationship with immune landscapes, and establish a metabolic index for accurate prognosis assessment.

    Authors: Xiao-wan Yu, Pei-wei She, Fang-chuan Chen, Ya-yu Chen, Shuang Zhou, Xi-min Wang, Xiao-rong Lin, Qiao-ling Liu, Zhi-jun Huang and Yu Qiu
    Citation: BMC Cancer 2024 24:230
  36. The irreversible epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) afatinib and dacomitinib are approved for first-line treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC)...

    Authors: Wen-Chien Cheng, Chi-Chien Lin, Wei-Chih Liao, Yu-Chao Lin, Chia-Hung Chen, Hung-Jen Chen, Chih-Yen Tu and Te-Chun Hsia
    Citation: BMC Cancer 2024 24:228
  37. Most patients with intrahepatic cholangiocarcinoma (ICC) have developed distant metastasis at the time of diagnosis, while there is rear related nomogram to predict the prognosis.

    Authors: Chen Yuan, Shubing Zou, Kai Wang and Zhigang Hu
    Citation: BMC Cancer 2024 24:227
  38. Breast ultrasound is highly sensitive, but its specificity is not as high for detecting malignant lesions. Auxiliary modalities like elastography, Color and Power Doppler ultrasound are used as adjuncts to yie...

    Authors: Mahboubeh Abedi, Leyla Sahebi, Bita Eslami, Azin Saberi, Marzieh Orouji, Sadaf Alipour and Shirin Shahsavarhaghighi
    Citation: BMC Cancer 2024 24:224
  39. Glioma is a primary brain tumor and the assessment of its molecular profile in a minimally invasive manner is important in determining treatment strategies. Among the molecular abnormalities of gliomas, mutati...

    Authors: Saiko Kino, Masayuki Kanamori, Yoshiteru Shimoda, Kuniyasu Niizuma, Hidenori Endo and Yuji Matsuura
    Citation: BMC Cancer 2024 24:222

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