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  1. Considering the age relevance of prostate cancer (PCa) and the involvement of the cGAS-STING pathway in aging and cancer, we aim to classify PCa into distinct molecular subtypes and identify key genes from the...

    Authors: Jie Yang, Zihan Xu, Weitao Zheng, Yifan Li, Qiang Wei and Lu Yang
    Citation: BMC Cancer 2024 24:732
    Content type: Research Published on:

  3. Chondroitin sulfate proteoglycan 4 pseudogene 12 (CSPG4P12) has been implicated in the pathogenesis of various cancers. This study aimed to evaluate the association of the CSPG4P12 polymorphism with esophageal sq...

    Authors: Hongxue Xu, Zhenbang Yang, Wenqian Hu, Xianlei Zhou, Zhi Zhang and Xuemei Zhang
    Citation: BMC Cancer 2024 24:729
    Content type: Research Published on:

  4. Circular RNA (circRNAs) have been found to play major roles in the progression of colorectal cancer (CRC). However, the functions of circ_0008345 (transcribed by PTK2) in regulating CRC development remain unde...

    Authors: Chaofeng Hou, Jinbo Liu, Junwei Liu, Danjie Yao, Fang Liang, Congpeng Qin and Zhiyong Ma
    Citation: BMC Cancer 2024 24:728
    Content type: Research Published on:

  5. The Naples Prognostic Score (NPS), integrating inflammatory and nutritional biomarkers, has been reported to be associated with the prognosis of various malignancies, but there is no report on intrahepatic cho...

    Authors: Cheng-Fei Du, Zhen-Yu Gao, Zhu-Ding Xu, Zheng-Kang Fang, Zi-Chen Yu, Zhe-Jin Shi, Kai-Di Wang, Wen-Feng Lu, Xiao-Kun Huang, Lei Jin, Tian-Wei Fu, Guo-Liang Shen, Jun-Wei Liu, Cheng-Wu Zhang, Dong-Sheng Huang and Lei Liang
    Citation: BMC Cancer 2024 24:727
    Content type: Research Published on:

  6. Polysaccharopeptide (PSP) is a potential active component in traditional Chinese medicine because of its anticancer effects on a variety of cancer cells and as immune enhancers of the immune system. Previous s...

    Authors: Cuixiang Xu, Lijun Sun, Huxia Wang, Jingying Sun, Yangmeng Feng, Xingguang Wang and Zhangjun Song
    Citation: BMC Cancer 2024 24:726
    Content type: Research Published on:

  7. Lymph node metastasis (LNM) is associated with worse prognosis in bladder urothelial carcinoma (BUC) patients. This study aimed to develop and validate machine learning (ML) models to preoperatively predict LN...

    Authors: Junjie Ji, Tianwei Zhang, Ling Zhu, Yu Yao, Jingchang Mei, Lijiang Sun and Guiming Zhang
    Citation: BMC Cancer 2024 24:725
    Content type: Research Published on:

  8. Tumor immune infiltration leads to poor prognosis of gastric cancer patients and seriously affects the life quality of gastric cancer patients. This study was based on bioinformatics to screen prognostic bioma...

    Authors: MeiHong Yu, Jingxuan Peng, Yanxu Lu, Sha Li and Ke Ding
    Citation: BMC Cancer 2024 24:724
    Content type: Research Published on:

  9. Among the 10% of pancreatic cancers that occur in a familial context, around a third carry a pathogenic variant in a cancer predisposition gene. Genetic studies of pancreatic cancer predisposition are limited ...

    Authors: Sofie Joris, Philippe Giron, Catharina Olsen, Sara Seneca, Alexander Gheldof, Shula Staessens, Rajendra Bahadur Shahi, Sylvia De Brakeleer, Erik Teugels, Jacques De Grève and Frederik J. Hes
    Citation: BMC Cancer 2024 24:723
    Content type: Research Published on:

  10. Childhood, adolescent, and young adult (CAYA) cancer survivors, at risk for late effects, including cancer-related fatigue, cardiovascular issues, and psychosocial challenges, may benefit from interventions st...

    Authors: Eline Bouwman, Iridi Stollman, Joyce Wilbers, Joyce J. M. Claessens, Dick Johan van Spronsen, Annet Bongaerts, Dionne Breij, Nicole M. A. Blijlevens, Hans Knoop, Rosella P. M. G. Hermens and Jacqueline J. Loonen
    Citation: BMC Cancer 2024 24:722
    Content type: Research Published on:

  11. Pneumonia and lung cancer are both major respiratory diseases, and observational studies have explored the association between their susceptibility. However, due to the presence of potential confounders and re...

    Authors: Lujia Song, Dongsheng Wu, Jiayang Wu, Jiexi Zhang, Weimin Li and Chengdi Wang
    Citation: BMC Cancer 2024 24:721
    Content type: Research Published on:

  12. To use data from the Global Burden of Disease (GBD) Study 2019 to report the global, regional and national rates and trends of deaths incidence, prevalence, disability-adjusted life years (DALYs) for Nasophary...

    Authors: Guoxin Huang, Yaojie Wang, Bingqing Qin, Jing Zeng, Huazhang tan, Dongdong Zhang and Qiuyang Wang
    Citation: BMC Cancer 2024 24:720
    Content type: Research Published on:

  13. Evaluation of human epidermal growth factor receptor 2 (HER2) overexpression caused by erb-b2 receptor tyrosine kinase 2 (ERBB2) amplification (AMP) by immunohistochemistry (IHC) and fluorescence in situ hybridiz...

    Authors: Hiroshi Ichikawa, Kenji Usui, Masaki Aizawa, Yoshifumi Shimada, Yusuke Muneoka, Yosuke Kano, Mika Sugai, Kazuki Moro, Yuki Hirose, Kohei Miura, Jun Sakata, Hiroshi Yabusaki, Satoru Nakagawa, Takashi Kawasaki, Hajime Umezu, Shujiro Okuda…
    Citation: BMC Cancer 2024 24:719
    Content type: Research Published on:

  15. To compare the efficacy and safety of transcatheter arterial chemoembolization (TACE) combined Lenvatinib plus Camrelizumab (TLC) in unresectable hepatocellular carcinoma (uHCC) with those of TACE alone .

    Authors: Zhihong Tang, Tao Bai, Tao Wei, Xiaobo Wang, Jie Chen, Jiazhou Ye, Shangqi Li, Meng Wei, Xingzhi Li, Youzhi Lin, Juan Tang, Lequn Li and Feixiang Wu
    Citation: BMC Cancer 2024 24:717
    Content type: Research Published on:

  16. To compare the diagnostic performance of the Node-RADS scoring system and lymph node (LN) size in preoperative LN assessment for rectal cancer (RC), and to investigate whether the selection of size as the prim...

    Authors: Yue Niu, Lu Wen, Yanhui Yang, Yi Zhang, Yi Fu, Qiang Lu, Yu Wang, Xiao Yu and Xiaoping Yu
    Citation: BMC Cancer 2024 24:716
    Content type: Research Published on:

  17. Resistance to immune checkpoint inhibitors (ICIs) represents a major unmet medical need in non-small cell lung cancer (NSCLC) patients. Vascular endothelial growth factor (VEGF) inhibition may reverse a suppre...

    Authors: Bo Zhang, Hongyu Liu, Chunlei Shi, Zhiqiang Gao, Runbo Zhong, Aiqin Gu, Tianqing Chu, Huimin Wang, Liwen Xiong, Wei Zhang, Xueyan Zhang, Bo Yan, Jiajun Teng, Weimin Wang, Hao Bai, Rong Qiao…
    Citation: BMC Cancer 2024 24:715
    Content type: Research Published on:

  18. Our study aims to explore the relationship, shared gene signature, and the underlying mechanisms that connect rheumatoid arthritis (RA) to colorectal cancer (CRC).

    Authors: Zhi-Qing Zhan, Ze-Min Huang, Qi-Wen Lan, Yu-Hua Luo, Jia-Xin Li, Ya-Fang Zheng, Ying-Zhou Chen, Pei-Zhen Chen, Tian-Ye Luo, Baoqing Sun and Zhangkai J Cheng
    Citation: BMC Cancer 2024 24:714
    Content type: Research Published on:

  20. Female gynecological cancers represent a serious public health problem, with 1,398,601 new diagnoses and 671,875 deaths per year worldwide. Antipsychotics are often used in psychiatric disorders, including sch...

    Authors: Francisco Cezar Aquino de Moraes, Renan Yuji Ura Sudo, Maria Eduarda Cavalcanti Souza, Marianne Rodrigues Fernandes and Ney Pereira Carneiro dos Santos
    Citation: BMC Cancer 2024 24:712
    Content type: Research Published on:

  21. Inflammatory factors have increasingly become a more cost-effective prognostic indicator for gastric cancer (GC). The goal of this study was to develop a prognostic score system for gastric cancer patients bas...

    Authors: Shaobo Zhang, Hongxia Xu, Wei Li, Jiuwei Cui, Qingchuan Zhao, Zengqing Guo, Junqiang Chen, Qinghua Yao, Suyi Li, Ying He, Qiuge Qiao, Yongdong Feng, Hanping Shi and Chunhua Song
    Citation: BMC Cancer 2024 24:711
    Content type: Research Published on:

  22. Papillary thyroid carcinoma (PTC) is globally prevalent and associated with an increased risk of lymph node metastasis (LNM). The role of cancer-associated fibroblasts (CAFs) in PTC remains unclear.

    Authors: Yixian Wang, Xin Li, Qingwei Gang, Yinde Huang, Mingyu Liu, Han Zhang, Shikai Shen, Yao Qi and Jian Zhang
    Citation: BMC Cancer 2024 24:710
    Content type: Research Published on:

  23. Pancreatic cancer, predominantly characterized by ductal adenocarcinoma (PDAC) accounts for 90% of cases and is the fourth leading cause of cancer-related deaths globally. Its incidence is notably increasing. ...

    Authors: Thomas Bardol, Antoine M. Dujon, Valerie Taly, Catherine Dunyach-Remy, Jean-Philippe Lavigne, Bruno Costa-Silva, Keerthi Kurma, Zahra Eslami-S, Laure Cayrefourcq, Cindy Canivet, Fabrice Muscari, Barbara Bournet and Catherine Alix-Panabières
    Citation: BMC Cancer 2024 24:709
    Content type: Study Protocol Published on:

  24. Novel antibody-drug conjugates (ADCs) drugs present a promising anti-cancer treatment, although survival benefits for HER2-positive advanced breast cancer (BC) remain controversial. The aim of this meta-analys...

    Authors: Zian Kang, Yuqing Jin, Huihui Yu, Su Li and Yingjie Qi
    Citation: BMC Cancer 2024 24:708
    Content type: Research Published on:

  26. Poly (ADP- ribose) polymerase inhibitors (PARPi) has been increasingly adopted for metastatic castration-resistance prostate cancer (mCRPC) patients with homologous recombination repair deficiency (HRD). Howev...

    Authors: Qiyu Zhu, Junru Chen, Haoyang Liu, Jinge Zhao, Chenhao Xu, Guangxi Sun and Hao Zeng
    Citation: BMC Cancer 2024 24:706
    Content type: Systematic Review Published on:

  27. Despite recent improvements in cancer detection and survival rates, managing cancer-related pain remains a significant challenge. Compared to neuropathic and inflammatory pain conditions, cancer pain mechanism...

    Authors: M. T. Carrillo-de-la-Peña, C. Fernandes, C. Castro and R. Medeiros
    Citation: BMC Cancer 2024 24:705
    Content type: Study Protocol Published on:

  29. Immunodeficient murine models are usually used as the preclinical models of osteosarcoma. Such models do not effectively simulate the process of tumorigenesis and metastasis. Establishing a suitable animal mod...

    Authors: Mengyu Yao, Zehua Lei, Feng Peng, Donghui Wang, Mei Li, Guoqing Zhong, Hongwei Shao, Jielong Zhou, Chang Du and Yu Zhang
    Citation: BMC Cancer 2024 24:703
    Content type: Research Published on:

  30. Cervical cancer is the fourth most common cancer in women, with an estimated 342,000 deaths worldwide in 2020. Current standard of care in the UK for locally advanced cervical cancer is concurrent chemoradioth...

    Authors: Peter Hoskin, Marina Lee, Denise Dunkley, Mary Danh, Robin Wickens, Geoff Saunders, Josh Northey, Simon Crabb, Vicky McFarlane, Azmat Sadozye, Rachel Cooper, Tony Mathew, Kate Haslett, Kim Reeves, Rachel Reed, Kamilla Bigos…
    Citation: BMC Cancer 2024 24:702
    Content type: Study Protocol Published on:

  31. Ovarian cancer is the first cause of death from gynecological malignancies mainly due to development of chemoresistance. Despite the emergence of PARP inhibitors, which have revolutionized the therapeutic mana...

    Authors: Lucie Thorel, Jordane Divoux, Justine Lequesne, Guillaume Babin, Pierre-Marie Morice, Romane Florent, Guillaume Desmartin, Lucie Lecouflet, Chloé Marde Alagama, Alexandra Leconte, Bénédicte Clarisse, Mélanie Briand, Roman Rouzier, Léopold Gaichies, Sandrine Martin-Françoise, Jean-François Le Brun…
    Citation: BMC Cancer 2024 24:701
    Content type: Study Protocol Published on:

  32. Although radical surgical resection is the most effective treatment for hepatocellular carcinoma (HCC), the high rate of postoperative recurrence remains a major challenge, especially in patients with alpha-fe...

    Authors: Xuanzhi Yan, Yicheng Li, Wanying Qin, Jiayi Liao, Jiaxing Fan, Yujin Xie, Zewen Wang, Siming Li and Weijia Liao
    Citation: BMC Cancer 2024 24:700
    Content type: Research Published on:

  33. [18F]Fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) is recommended during diagnostic work-up for ovarian cancer; however, [18F]FDG PET has several inherent limitations. The novel oncologic PET-t...

    Authors: Morten Bentestuen, Morten Ladekarl, Aage Knudsen and Helle D. Zacho
    Citation: BMC Cancer 2024 24:699
    Content type: Study Protocol Published on:

  34. Tumor-associated macrophages (TAMs) constitute a substantial part of human hepatocellular carcinoma (HCC). The present study was devised to explore TAM diversity and their roles in HCC progression.

    Authors: Shiqi Liu, Shuairan Zhang, Hang Dong, Xiuli Jin, Jing Sun, Haonan Zhou, Yifan Jin, Yiling Li and Gang Wu
    Citation: BMC Cancer 2024 24:698
    Content type: Research Published on:

  36. Inflammation, malnutrition, and cancer are intricately interconnected. Despite this, only a few studies have delved into the relationship between inflammatory malnutrition and the risk of death among cancer su...

    Authors: Chaoqun Liang, Chao Zhang, Jun Song, Lin Yan, Yun Xiao, Nan Cheng, Han Wu, Xiaohong Chen and Jianming Yang
    Citation: BMC Cancer 2024 24:696
    Content type: Research Published on:

  37. Cervical cancer (CxCa), although preventable, is still among the most prevalent cancers in women. Mortality from this cancer is high, especially in low-income countries where preventive strategies are often la...

    Authors: Boshra Ali, Andrzej Galbarczyk, Grazyna Jasienska, Maryam Ba-Break and Hülya Gül
    Citation: BMC Cancer 2024 24:695
    Content type: Research Published on:

  39. Continued smoking after a cancer diagnosis can be associated with lower treatment tolerance, poorer outcomes, and reduced quality of life compared to non-smoking cancer patients or to those who have quit. Yet ...

    Authors: Frederike Bokemeyer, Lisa Lebherz, Carsten Bokemeyer, Kathleen Gali, Holger Schulz and Christiane Bleich
    Citation: BMC Cancer 2024 24:693
    Content type: Research Published on:

  40. Gliomas are the deadliest malignant tumors of the adult central nervous system. We previously discovered that beta2-microglobulin (B2M) is abnormally upregulated in glioma tissues and that it exerts a range of...

    Authors: Zhen-Yuan Liu, Feng Tang, Jing Wang, Jin-Zhou Yang, Xi Chen, Ze-Fen Wang and Zhi-Qiang Li
    Citation: BMC Cancer 2024 24:692
    Content type: Research Published on:

  42. The prognostic value of multifocality in paediatric papillary thyroid carcinoma (PTC) patients remains a subject of debate. This study aimed to explore the clinical significance and prognostic value of multifo...

    Authors: Yuxiao Sun, Yihao Liu, Hongqiang Li, Yifeng Tang, Weihao Liu, Yifei Zhang and Detao Yin
    Citation: BMC Cancer 2024 24:690
    Content type: Research Published on:

  44. Multicenter non-small cell lung cancer (NSCLC) patient data is information-rich. However, its direct integration becomes exceptionally challenging due to constraints involving different healthcare organization...

    Authors: Yuan Liu, Jinzao Huang, Jyh-Cheng Chen, Wei Chen, Yuteng Pan and Jianfeng Qiu
    Citation: BMC Cancer 2024 24:688
    Content type: Research Published on:

  45. Background The methylation of SHOX2 and RASSF1A shows promise as a potential biomarker for the early screening of lung cancer, offering a solution to remedy the limitations of morphological diagnosis. The aim of ...

    Authors: Jiaping Zhao, Yu Lu, Xiaosha Ren, Tingting Bian, Jia Feng, Hui Sun, Lei Liu, Bin She, Yifei Liu and Honggang Ke
    Citation: BMC Cancer 2024 24:687
    Content type: Research Published on:

  46. Primary tracheal tumors are very rare and their management is not definitely established. Due to its rarity, providing patient care in terms of optimal management poses a considerable challenge. The purpose of...

    Authors: Aleksandra Piórek, Adam Płużański, Magdalena Knetki-Wróblewska, Kinga Winiarczyk, Sylwia Tabor, Paweł Teterycz, Dariusz M. Kowalski and Maciej Krzakowski
    Citation: BMC Cancer 2024 24:686
    Content type: Research Published on:

  47. Gastric cancer is one of the most common tumors worldwide, and most patients are deprived of treatment options when diagnosed at advanced stages. PRDM14 has carcinogenic potential in breast and non-small cell ...

    Authors: Xiao Li, Cong Wang, Youcai Wang, Xiaobing Chen, Zhi Li, Jianwei Wang and Yingjun Liu
    Citation: BMC Cancer 2024 24:685
    Content type: Research Published on:

  48. Many randomized controlled trials (RCTs) and network meta-analyses have demonstrated that the progression-free survival (PFS) and overall survival (OS) of advanced non-small cell lung cancer (NSCLC) patients c...

    Authors: Wen Hui, Wentan Li, Ruomeng Song, Yu Xin, Changjin Wu, Zhixiang Gao, Mingyue Zhang, Huazhang Wu, Min Zhu and Yuanyi Cai
    Citation: BMC Cancer 2024 24:684
    Content type: Research Published on:

  49. MicroRNAs (miRNAs) emerge in various organisms, ranging from viruses to humans, and play crucial regulatory roles within cells, participating in a variety of biological processes. In numerous prediction method...

    Authors: Hou Biyu, Li Mengshan, Hou Yuxin, Zeng Ming, Wang Nan and Guan Lixin
    Citation: BMC Cancer 2024 24:683
    Content type: Research Published on:

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