Doughman RL, Firestone AJ, Anderson RA: Phosphatidylinositol phosphate kinases put PI4,5P(2) in its place. J Membr Biol. 2003, 194: 77-89. 10.1007/s00232-003-2027-7.
Article
CAS
PubMed
Google Scholar
Logan MR, Mandato CA: Regulation of the actin cytoskeleton by PIP2 in cytokinesis. Biol Cell. 2006, 98: 377-388. 10.1042/BC20050081.
Article
CAS
PubMed
Google Scholar
Janetopoulos C, Devreotes P: Phosphoinositide signaling plays a key role in cytokinesis. J Cell Biol. 2006, 174: 485-490. 10.1083/jcb.200603156.
Article
CAS
PubMed
PubMed Central
Google Scholar
Scheid MP, Huber M, Damen JE, Hughes M, Kang V, Neilsen P, Prestwich GD, Krystal G, Duronio V: Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockout mice. J Biol Chem. 2002, 277: 9027-9035. 10.1074/jbc.M106755200.
Article
CAS
PubMed
Google Scholar
Itoh N, Semba S, Ito M, Takeda H, Kawata S, Yamakawa M: Phosphorylation of Akt/PKB is required for suppression of cancer cell apoptosis and tumor progression in human colorectal carcinoma. Cancer. 2002, 94: 3127-3134. 10.1002/cncr.10591.
Article
CAS
PubMed
Google Scholar
Roy HK, Olusola BF, Clemens DL, Karolski WJ, Ratashak A, Lynch HT, Smyrk TC: AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis. Carcinogenesis. 2002, 23: 201-205. 10.1093/carcin/23.1.201.
Article
CAS
PubMed
Google Scholar
Vivanco I, Sawyers CL: The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer. 2002, 2: 489-501. 10.1038/nrc839.
Article
CAS
PubMed
Google Scholar
Hennessy BT, Smith DL, Ram PT, Lu Y, Mills GB: Exploiting the PI3K/AKT pathway for cancer drug discovery. Nat Rev Drug Discov. 2005, 4: 988-1004. 10.1038/nrd1902.
Article
CAS
PubMed
Google Scholar
Kozikowski AP, Sun H, Brognard J, Dennis PA: Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt. J Am Chem Soc. 2003, 125: 1144-1145. 10.1021/ja0285159.
Article
CAS
PubMed
Google Scholar
Castillo SS, Brognard J, Petukhov PA, Zhang C, Tsurutani J, Granville CA, Li M, Jung M, West KA, Gills JG, Kozikowski AP, Dennis PA: Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues. Cancer Res. 2004, 64: 2782-2792. 10.1158/0008-5472.CAN-03-1530.
Article
CAS
PubMed
Google Scholar
Gills JJ, Castillo SS, Zhang C, Petukhov PA, Memmott RM, Hollingshead M, Warfel N, Han J, Kozikowski AP, Dennis PA: Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms. J Biol Chem. 2007, 282: 27020-27029. 10.1074/jbc.M701108200.
Article
CAS
PubMed
Google Scholar
Gills JJ, Holbeck S, Hollingshead M, Hewitt SM, Kozikowski AP, Dennis PA: Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt. Mol Cancer Ther. 2006, 5: 713-722. 10.1158/1535-7163.MCT-05-0484.
Article
CAS
PubMed
Google Scholar
Phillips WA, St Clair F, Munday AD, Thomas RJ, Mitchell CA: Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors. Cancer. 1998, 83: 41-47. 10.1002/(SICI)1097-0142(19980701)83:1<41::AID-CNCR6>3.0.CO;2-H.
Article
CAS
PubMed
Google Scholar
Samuels Y, Wang Z, Bardelli A, Silliman N, Ptak J, Szabo S, Yan H, Gazdar A, Powell SM, Riggins GJ, Willson JKV, Markowitz S, Kinzler KW, Vogelstein B, Velculescu VE: High frequency of mutations of the PIK3CA gene in human cancers. Science. 2004, 304: 554-10.1126/science.1096502.
Article
CAS
PubMed
Google Scholar
Gayet J, Zhou XP, Duval A, Rolland S, Hoang JM, Cottu P, Hamelin R: Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines. Oncogene. 2001, 20: 5025-5032. 10.1038/sj.onc.1204611.
Article
CAS
PubMed
Google Scholar
Shamir R, Maron-Katz A, Tanay A, Linhart C, Steinfeld I, Sharan R, Shiloh Y, Elkon R: EXPANDER--an integrative program suite for microarray data analysis. BMC Bioinformatics. 2005, 6: 232-10.1186/1471-2105-6-232.
Article
PubMed
PubMed Central
Google Scholar
Naito Y, Okada M, Yagisawa H: Phospholipase C isoforms are localized at the cleavage furrow during cytokinesis. J Biochem. 2006, 140: 785-791. 10.1093/jb/mvj209.
Article
CAS
PubMed
Google Scholar
Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, Lerner J, Brunet J, Subramanian A, Ross KN, Reich M, Hieronymus H, Wei G, Armstrong SA, Haggarty SJ, Clemons PA, Wei R, Carr SA, Lander ES, Golub TR: The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science. 2006, 313: 1929-1935. 10.1126/science.1132939.
Article
CAS
PubMed
Google Scholar
Han JY, Heo JS, Lee YJ, Lee JH, Taub M, Han HJ: Dopamine stimulates 45Ca2+ uptake through cAMP, PLC/PKC, and MAPKs in renal proximal tubule cells. J Cell Physiol. 2007, 211: 486-494. 10.1002/jcp.20956.
Article
CAS
PubMed
Google Scholar
Raemaekers T, Ribbeck K, Beaudouin J, Annaert W, Van Camp M, Stockmans I, Smets N, Bouillon R, Ellenberg J, Carmeliet G: NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization. J Cell Biol. 2003, 162: 1017-1029. 10.1083/jcb.200302129.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ribbeck K, Raemaekers T, Carmeliet G, Mattaj IW: A role for NuSAP in linking microtubules to mitotic chromosomes. Curr Biol. 2007, 17: 230-236. 10.1016/j.cub.2006.11.050.
Article
CAS
PubMed
Google Scholar
Paramasivam M, Chang YJ, LoTurco JJ: ASPM and citron kinase co-localize to the midbody ring during cytokinesis. Cell Cycle. 2007, 6: 1605-1612.
Article
CAS
PubMed
Google Scholar
Holt SV, Vergnolle MAS, Hussein D, Wozniak MJ, Allan VJ, Taylor SS: Silencing Cenp-F weakens centromeric cohesion, prevents chromosome alignment and activates the spindle checkpoint. J Cell Sci. 2005, 118: 4889-4900. 10.1242/jcs.02614.
Article
CAS
PubMed
Google Scholar
Jiang W, Jimenez G, Wells NJ, Hope TJ, Wahl GM, Hunter T, Fukunaga R: PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. Mol Cell. 1998, 2: 877-885. 10.1016/S1097-2765(00)80302-0.
Article
CAS
PubMed
Google Scholar
Mollinari C, Kleman J, Saoudi Y, Jablonski SA, Perard J, Yen TJ, Margolis RL: Ablation of PRC1 by small interfering RNA demonstrates that cytokinetic abscission requires a central spindle bundle in mammalian cells, whereas completion of furrowing does not. Mol Biol Cell. 2005, 16: 1043-1055. 10.1091/mbc.E04-04-0346.
Article
CAS
PubMed
PubMed Central
Google Scholar
Vanhaesebroeck B, Waterfield MD: Signaling by distinct classes of phosphoinositide 3-kinases. Exp Cell Res. 1999, 253: 239-254. 10.1006/excr.1999.4701.
Article
CAS
PubMed
Google Scholar
Taylor CW: Controlling calcium entry. Cell. 2002, 111: 767-769. 10.1016/S0092-8674(02)01197-2.
Article
CAS
PubMed
Google Scholar
Olas B, Wachowicz B, Holmsen H, Fukami MH: Resveratrol inhibits polyphosphoinositide metabolism in activated platelets. Biochim Biophys Acta. 2005, 1714: 125-133. 10.1016/j.bbamem.2005.06.008.
Article
CAS
PubMed
Google Scholar
Whyte DB, Holbeck SL: Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines. Biochem Biophys Res Commun. 2006, 340: 469-475. 10.1016/j.bbrc.2005.12.025.
Article
CAS
PubMed
Google Scholar