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Figure 1 | BMC Cancer

Figure 1

From: Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations

Figure 1

PIAs inhibit AKT phosphorylation after serum starvation. (A) Western blot analysis of cells serum starved for 24 hours prior to incubation for two hours with SH-5 and SH-6, respectively. The phosphorylation status of AKT was determined using specific antibodies. The detection of total AKT served as a loading control. (B) Morphological alterations induced in serum starved cells after 24 hours of treatment with SH-5 and SH-6, respectively. DMSO was used as a solvent control.

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BMC Cancer

ISSN: 1471-2407

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