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Figure 5 | BMC Cancer

Figure 5

From: Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations

Figure 5

Absence of visible mitotic defects in PIA-treated SW480 cells. Fixed SW480 cells preincubated with either DMSO (A, C and E) or SH-6 (B, D and F) for 48 hours were stained with anti-PRC1 (red), anti-γ-Tubulin (green) and DAPI (blue). We selected typical cells in different stages of the mitosis based on the DAPI staining: (A) and (B) cells in metaphase, (C) and (D) cells in anaphase, (E) and (F) cells in telophase (white arrows mark the midbodies).

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BMC Cancer

ISSN: 1471-2407

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