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Figure 4 | BMC Cancer

Figure 4

From: Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations

Figure 4

PIAs induce binucleation in SW480 cells. (A) Confocal Laser scanning images of cells treated with SH-5, SH-6 or DMSO. The green staining indicates Lamin A/C, the red Vimentin and the blue DAPI. (B) Percentage of binucleated cells determined microscopically after treatment with the indicated inhibitors or the DMSO control. The total number of cells was set to 100. Data sets were analyzed using the Student's t-Test. A p-value < 0.05 was considered as significant and marked by asterisks.

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BMC Cancer

ISSN: 1471-2407

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