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  1. To predict the very early recurrence (VER) of patients with intrahepatic cholangiocarcinoma (ICC) based on TLSs and MVI status, and further perform prognosis stratifications.

    Authors: Ying Xu, Zhuo Li, Yanzhao Zhou, Yi Yang, Jingzhong Ouyang, Lu Li, Zhen Huang, Feng Ye, Jianming Ying, Hong Zhao, Jinxue Zhou and Xinming Zhao
    Citation: BMC Cancer 2023 23:1009
  2. To clarify the relationship between p53 immunohistochemistry (IHC) staining and TP53 alterations (including mutations and deletions) in large B-cell lymphomas (LBCLs) and to explore the possibility of p53 IHC exp...

    Authors: Xinyi Li, Danju Luo, Liling Zhang, Qiuhui Li, Jun Fan, Jiwei Zhang, Bo Huang, Ming Yang, Xiu Nie, Xiaona Chang and Huaxiong Pan
    Citation: BMC Cancer 2023 23:1008
  3. CANT1, as calcium-activated protein nucleotidase 1, is a kind of phosphatase. It is overexpressed in some tumors and related to poor prognosis, but few studies explore its function and carcinogenic mechanism i...

    Authors: Ting Liu, Zhi-zhao Li, Lei Sun, Kun Yang, Jia-min Chen, Xiao-yi Han, Li-ming Qi, Xin-gang Zhou and Peng Wang
    Citation: BMC Cancer 2023 23:1007
  4. The use of regorafenib in the treatment of hepatocellular carcinoma (HCC) is widespread. Albumin-Bilirubin (ALBI) has been shown to be a potential prognostic marker for regorafenib treatment, but its prognosti...

    Authors: Huilin Xu, Dedong Cao, Dingjie Zhou, Nan Zhao, Xixian Tang, Vishalkumar G. Shelat, Hrishikesh Samant, Sanjaya K. Satapathy, Francisco Tustumi, Giuseppe Aprile, Anbing He, Ximing Xu and Wei Ge
    Citation: BMC Cancer 2023 23:1006
  5. SH2 domain containing 1A (SH2D1A) expression has been linked to cancer progression. However, the functions of SH2D1A in hepatocellular carcinoma (HCC) have not been reported.

    Authors: Qian-Ming Xiang, Ni Jiang, Yue-Feng Liu, Yuan-Biao Wang, De-An Mu, Rong Liu, Lu-Yun Sun, Wei Zhang, Qiang Guo and Kai Li
    Citation: BMC Cancer 2023 23:1005
  6. Brain metastases are the most common intracranial tumours. Variation exists in the use of stereotactic radiosurgery for patients with 10 or more brain metastases. Concerns include an increasing number of brain...

    Authors: Hamoun Rozati, Jiarong Chen and Matt Williams
    Citation: BMC Cancer 2023 23:1004
  7. Genitourinary small cell carcinoma is rare, and has a poor prognosis. However, effective treatment options for this disease are limited. We present a study to assess the efficacy of chemotherapy alone or combi...

    Authors: Riqing Huang, Meiting Chen, Haifeng Li, Xin An, Cong Xue, Anqi Hu, Ditian Shu, Wei Yang, Fangjian Zhou, Dan Sui, Kai Yao, Yonghong Li, Zhiming Wu, Zhiyong Li, Zhuowei Liu and Yanxia Shi
    Citation: BMC Cancer 2023 23:1002
  8. Recent studies have shown that the high incidence and low cure rate of hepatocellular carcinoma (HCC) have not improved significantly. Surgery and liver transplantation are the mainstays of prolonging the surv...

    Authors: Weiwei Yuan, Yuanmin Xu, Zhiheng Wu, Yang Huang, Lei Meng, Shiping Dai, Songcheng Ying, Zhangming Chen and Aman Xu
    Citation: BMC Cancer 2023 23:1001
  9. Two ROS1 tyrosine kinase inhibitors have been approved for ROS1 fusion positive (ROS1+) non-small cell lung cancer (NSCLC) tumors. We performed a pan-tumor analysis of the incidence of ROS1 fusions to assess if m...

    Authors: Misako Nagasaka, Shannon S. Zhang, Yasmine Baca, Joanne Xiu, Jorge Nieva, Ari Vanderwalde, Jeffrey J. Swensen, David Spetzler, Wolfgang Michael Korn, Luis E. Raez, Stephen V. Liu and Sai-Hong Ignatius Ou
    Citation: BMC Cancer 2023 23:1000
  10. Little is known on how denosumab reduces skeletal-related events (SREs) by bone metastases from solid tumors. We sought to evaluate the effect of denosumab administration in patients with bone metastases from ...

    Authors: Kohei Mizuta, Hiromichi Oshiro, Ryo Katsuki, Yuichi Tsuha, Yusuke Aoki, Yasunori Tome and Kotaro Nishida
    Citation: BMC Cancer 2023 23:999
  11. We previously identified 16,772 colorectal cancer-associated hypermethylated DNA regions that were also detectable in precancerous colorectal lesions (preCRCs) and unrelated to normal mucosal aging. We have no...

    Authors: Sija Sajibu, Emanuel Sonder, Amit Tiwari, Stephany Orjuela, Hannah R. Parker, Olivier The Frans, Christoph Gubler, Giancarlo Marra and Mark D. Robinson
    Citation: BMC Cancer 2023 23:998
  12. Immunosuppression is a significant factor contributing to the poor prognosis of cancer. S100P, a member of the S100 protein family, has been implicated in various cancers. However, its role in the tumor microenvi...

    Authors: Weiwei Hao, Yanyan Zhang, Jingwen Dou, Pu Cui and Jicun Zhu
    Citation: BMC Cancer 2023 23:997
  13. Response of locally advanced gastric cancer (LAGC) to neoadjuvant therapy (NAT) may be associated with prognosis, but which of the clinical or pathological evaluation can accurately predict a favorable prognos...

    Authors: Chongyuan Sun, Penghui Niu, Xiaojie Zhang, Lulu Zhao, Wanqing Wang, Xiaoyi Luan, Xue Han, Yingtai Chen and Dongbing Zhao
    Citation: BMC Cancer 2023 23:996
  14. Endometrial carcinoma (EC) is a malignant tumor of the female reproductive tract that has been associated with increased morbidity and mortality. This study aimed to identify biomarkers and potential therapeut...

    Authors: Qirong Hao, Hongqin Wu, Erniao Liu and Lina Wang
    Citation: BMC Cancer 2023 23:995
  15. A national framework for population-based cancer registration was established in Russia in the late 1990s. Data comparability and validity analyses found substantial differences across ten population-based can...

    Authors: Anton Barchuk, Rustam Tursun-zade, Ekaterina Nazarova, Yuri Komarov, Ekaterina Tyurina, Yulia Tumanova, Alexey Belyaev and Ariana Znaor
    Citation: BMC Cancer 2023 23:994
  16. This study aimed to explore the potential interaction between dietary intake and genetics on incident colorectal cancer (CRC) and whether adherence to healthy dietary habits could attenuate CRC risk in individ...

    Authors: Tung Hoang, Sooyoung Cho, Ji-Yeob Choi, Daehee Kang and Aesun Shin
    Citation: BMC Cancer 2023 23:993
  17. We aim to identify the multifaceted risk factors that can affect the development of severe radiation pneumonitis (RP) in patients with non-small cell lung cancer (NSCLC) treated with curative high-dose radioth...

    Authors: Hakyoung Kim, Jeongeun Hwang, Sun Myung Kim, Juwhan Choi and Dae Sik Yang
    Citation: BMC Cancer 2023 23:992
  18. The purpose of this study was to develop and validate a radiomics nomogram for predicting thymidylate synthase (TYMS) status in hepatocellular carcinoma (HCC) by using Gd-DTPA contrast enhanced MRI.

    Authors: Zongren Ding, Yijun Wu, Guoxu Fang, Zhaowang Lin, Kongying Lin, Jun Fu, Qizhen Huang, Yanyan Tang, Wuyi You, Jingfeng Liu and Yongyi Zeng
    Citation: BMC Cancer 2023 23:991
  19. To investigate how Fusobacterium nucleatum (Fn) promotes oxidative stress and mediates proliferation and autophagy in hypopharyngeal squamous cell carcinoma (HPSCC).

    Authors: Hui-Ching Lau, Xiaohui Yuan, Huiying Huang, Ming Zhang, Chi-Yao Hsueh and Hongli Gong
    Citation: BMC Cancer 2023 23:990
  20. Long noncoding RNAs (lncRNAs) are considered key players in the formation and development of tumors. Herein, Gene Expression Profiling Interactive Analysis (GEPIA) was employed as a bioinformatics technology. ...

    Authors: Zhengang Wang, Yang Cui, Fanchen Wang, Lixia Xu, Yan Yan, Xiaoguang Tong and Hua Yan
    Citation: BMC Cancer 2023 23:989
  21. The machine learning models with dose factors and the deep learning models with dose distribution matrix have been used to building lung toxics models for radiotherapy and achieve promising results. However, f...

    Authors: Liming Sheng, Lei Zhuang, Jing Yang, Danhong Zhang, Ying Chen, Jie Zhang, Shengye Wang, Guoping Shan, Xianghui Du and Xue Bai
    Citation: BMC Cancer 2023 23:988
  22. Laparoscopic gastrectomy (LG) is considered a standard treatment for clinical stage I gastric cancer. Nevertheless, LG has some drawbacks, such as motion restriction and difficulties in spatial perception. Rob...

    Authors: Rie Makuuchi, Masanori Terashima, Mitsumi Terada, Junki Mizusawa, Ryosuke Kita, Masanori Tokunaga, Takeshi Omori, Toshiyasu Ojima, Kazuhisa Ehara, Masaya Watanabe, Yoshitomo Yanagimoto, Souya Nunobe, Takahiro Kinoshita, Seiji Ito, Yasunori Nishida, Jun Hihara…
    Citation: BMC Cancer 2023 23:987
  23. Mitofusin 2 (MFN2) plays an important role in many tumors, but how its role in renal clear cell carcinoma needs further research.

    Authors: Bin Zhang, Dali Han, LiMing Yang, Yang He, Shujun Yang, Hongbo Wang, Xingxing Zhang, Yuelin Du, Wei Xiong, Hualan Ha and Panfeng Shang
    Citation: BMC Cancer 2023 23:986
  24. One of the causes of colon and gastric cancer is the dysregulation of carcinogenic genes, tumor inhibitors, and micro-RNA. The purpose of this study is to apply rs10811661 polymorphism in CDKN2A /B gene as an ...

    Authors: Maria Beihaghi, Reza Sahebi, Mohammad Reza Beihaghi, Raheleh Khosravi Nessiani, Majedeh Ramian Yarasmi, Sajad Gholamalizadeh, Fatemeh Shahabnavaie and Mitra shojaei
    Citation: BMC Cancer 2023 23:985
  25. Neoadjuvant chemotherapy (NAC) has been widely applied in operable breast cancer patients. This study aim to identify the predictive factors of overall survival(OS) and recurrence free survival (RFS) in breast...

    Authors: Danzhi Chen, Qinchuan Wang, Minjun Dong, Fei Chen, Aihua Huang, Cong Chen, Yi Lu, Wenhe Zhao and Linbo Wang
    Citation: BMC Cancer 2023 23:984
  26. Despite decades of effort to reduce racial cancer disparities, Black people continue to die at higher rates from cancer than any other U.S. racial group. Because prevention is a key to the cost-effective and l...

    Authors: Nao Hagiwara, Nadia Harika, Erin P. Carmany, Yongyun Shin, Susan Eggly, Shawn C. T. Jones and John Quillin
    Citation: BMC Cancer 2023 23:983
  27. About 10% of non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations are harbored as uncommon mutations. This study aimed to explore the efficacy and safety of dacomitin...

    Authors: Xingxiang Pu, Yu Zhou, Yi Kong, Bolin Chen, Aifang Yang, Jia Li, Kang Li, Yan Xu and Lin Wu
    Citation: BMC Cancer 2023 23:982
  28. Chemotherapy is a well-known risk factor for sensorial and motor disturbances. Chemotherapy induced peripheral neuropathy (CIPN) which predominantly affects sensory nerves might cause a diminished fine motor f...

    Authors: Alper Tuğral, Zeynep Arıbaş, Murat Akyol and Yeşim Bakar
    Citation: BMC Cancer 2023 23:981
  29. Aponermin, a circularly permuted tumor necrosis factor-related apoptosis-inducing ligand, is a potential death receptor 4/5-targeted antitumour candidate. Previous phase 1/2 studies have demonstrated the effic...

    Authors: Zhongjun Xia, Yun Leng, Baijun Fang, Yang Liang, Wei Li, Chengcheng Fu, Linhua Yang, Xiaoyan Ke, Hua Jiang, Jianyu Weng, Li Liu, Yaozhong Zhao, Xuejun Zhang, Zhongxia Huang, Aichun Liu, Qingzhi Shi…
    Citation: BMC Cancer 2023 23:980
  30. Weekly paclitaxel + ramucirumab (wPTX + RAM) therapy is recommended as the standard second-line chemotherapy regimen for unresectable advanced/recurrent gastric cancer (GC) or esophagogastric junction cancer. ...

    Authors: Katsuhiko Nara, Takehito Yamamoto, Hiroharu Yamashita, Koichi Yagi, Tappei Takada, Yasuyuki Seto and Hiroshi Suzuki
    Citation: BMC Cancer 2023 23:979
  31. Cell division cycle 6 (CDC6) is a key licensing factor in the assembly of pre-replicative complexes at origins of replication. The role of CDC6 in the pathogenesis of in diffuse larger B-cell lymphoma (DLBCL) ...

    Authors: Mingfang Shen, Yunfeng Zhang, Lun Tang, Qinyan Fu, Jiawei Zhang, Yang Xu, Hui Zeng and Yuan Li
    Citation: BMC Cancer 2023 23:978
  32. This study surveyed circular RNA CCT3 in bladder cancer (BCa). We recruited 85 BCa patients and 40 normal controls (Normal) and collected clinical specimens for analysis. circRNA CCT3 expression was analyzed b...

    Authors: Lin Luo, Qingzhi Xie, Yunchou Wu, Ping Li, FuQiang Qin, Dunming Liao and KangNing Wang
    Citation: BMC Cancer 2023 23:977
  33. Current treatment of acute leukemia is based on anthracycline chemotherapy. Anthracyclines, despite improving patient survival, have serious cardiotoxicity and therefore cardiac monitoring should be a priority...

    Authors: Xi Zhou, Yue Weng, Tiantian Jiang, Wenxin Ou, Nan Zhang, Qian Dong and Xiaoqiong Tang
    Citation: BMC Cancer 2023 23:976
  34. Several factors contribute to delayed presentation with ovarian cancer (OC) symptoms including poor symptom awareness and barriers to seeking help. This study explored the anticipated time to seek medical advi...

    Authors: Mohamedraed Elshami, Sondos Al-Madhoun, Mohammed Alser, Ibrahim Al-Slaibi, Areej Yaseen, Aya Tuffaha, Hadeel Jabr, Sara Ubaiat, Salma Khader, Reem Khraishi, Inas Jaber, Zeina Abu Arafeh, Aya Alqattaa, Asmaa Abd El Hadi, Ola Barhoush, Maysun Hijazy…
    Citation: BMC Cancer 2023 23:975
  35. As a molecule controlling the assembly of central spindles and recruitment of midzone component, coiled-coil domain-containing protein 69 (CCDC69) plays an important role in multiple cancers. Currently, the re...

    Authors: Zhen Wang, Huiyang Ren, Guolian Zhu, Lei Zhang, Hongyi Cao and Bo Chen
    Citation: BMC Cancer 2023 23:974
  36. Hepatocyte growth factor (HGF) is a peptide-containing multifunctional cytokine, which is overexpressed and/or activated in multiple malignancies and is reported to be associated with tumor development and inf...

    Authors: Cong Zhao, Li Tong, Bin Liu, Fei Qi, Zhiyun Zhang, Yi Guo, Yanxia Liu, Ying Wang, Lina Zhang, Baohua Lu, Baolan Li and Tongmei Zhang
    Citation: BMC Cancer 2023 23:973
  37. In recent years, hyperthermia has been widely applied as a novel strategy for cancer treatment due to its multiple antitumour effects. In particular, the potential influences of hyperthermia on the tumour immu...

    Authors: Yin Huaqi, Dong Bingqi, Zhao Yanhui, Ma Yongkang, Zhao Shiming, Sun Zhenghui, Du Zheng, Peng Jiangshan and Yang Tiejun
    Citation: BMC Cancer 2023 23:972
  38. Cancer cells express immunosuppressive molecules, such as programmed death ligands (PD-L)1 and PD-L2, enabling evasion from the host’s immune system. Cancer cells synthesize and secrete acetylcholine (ACh), ac...

    Authors: Nyanbol Kuol, Janusz Godlewski, Zbigniew Kmiec, Sara Vogrin, Sarah Fraser, Vasso Apostolopoulos and Kulmira Nurgali
    Citation: BMC Cancer 2023 23:971
  39. CalliSpheres® is a microsphere that is already widely used for primary liver cancer treatment; however, its application in colorectal cancer liver metastasis (CRLM) is limited. The current study aimed to inves...

    Authors: Haitao Li, Xiaolin Zhang, Wenjiang Zhao, Fei Cai, Jia Qin and Jie Tian
    Citation: BMC Cancer 2023 23:970
  40. This study aimed to explore whether the addition of sarcopenia and visceral adiposity could improve the accuracy of model predicting progression-free survival (PFS) in hepatocellular carcinoma (HCC).

    Authors: Yao Liu, Sirui Fu, Xiangrong Yu, Jinxiong Zhang, Siyu Zhu, Yang Yang, Jianwen Huang, Hanlin Luo, Kai Tang, Youbing Zheng, Yujie Zhao, Xiaoqiong Chen, Meixiao Zhan, Xiaofeng He, Qiyang Li, Chongyang Duan…
    Citation: BMC Cancer 2023 23:969
  41. There is limited information of radical radiotherapy (RT) on lymphoepithelial carcinoma of salivary gland (LECSG) regarding to the rarity of the disease. We conducted this retrospective study that evaluated th...

    Authors: Xiaoshuang Niu, Peiyao Liu, Xiaoshen Wang and Chaosu Hu
    Citation: BMC Cancer 2023 23:968
  42. In case of locally advanced and/or non-metastatic unresectable esophageal cancer, definitive chemoradiotherapy (CRT) delivering 50 Gy in 25 daily fractions in combination with platinum-based regimen remains th...

    Authors: Anouchka Modesto, David Tougeron, Pierre Tremolières, Philippe Ronchin, Ariane Darut Jouve, Delphine Argo Leignel, Véronique Vendrely, Olivier Riou, Jérôme Martin-Babau, Samuel Le Sourd, Xavier Mirabel, Thomas Leroy, Florence Huguet, Lucile Montaigne, Isabelle Baumgaertner, Marion Deslandres…
    Citation: BMC Cancer 2023 23:966
  43. Genetic and lifestyle factors both contribute to the pathogenesis of bladder cancer, but the extent to which the increased genetic risk can be mitigated by adhering to a healthy lifestyle remains unclear. We a...

    Authors: Qiangsheng He, Siqing Wu, Ying Zhou, Yuchen Liu, Bin Xia, Wenjing Li, Jinyu Zhao, Ningning Mi, Peng Xie, Xiwen Qin, Jinqiu Yuan and Yihang Pan
    Citation: BMC Cancer 2023 23:965
  44. The long-term dynamic recurrence hazard of locally advanced gastric cancer (LAGC) in the clinical setting of adjuvant chemotherapy (ACT) remains unclear.

    Authors: Dong Wu, Jun Lu, Zhen Xue, Qing Zhong, Bin-bin Xu, Hua-Long Zheng, Guo-sheng Lin, Li-li Shen, Jia Lin, Jiao-bao Huang, Davit Hakobyan, Ping Li, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Long-Long Cao…
    Citation: BMC Cancer 2023 23:964
  45. The PACIFIC study has demonstrated that the administration of durvalumab following concurrent chemoradiotherapy can significantly improve both overall survival and progression-free survival rates in patients w...

    Authors: Zhenyi Yang, Wen Zhong, Yixuan Luo and Chunli Wu
    Citation: BMC Cancer 2023 23:962
  46. Cervical cancer is a public health problem. It is one of the leading causes of death in women worldwide and the second leading cause of female cancer-related deaths. Cervical cancer screening enables the detec...

    Authors: Tangut Misgun and Dereje Bayissa Demissie
    Citation: BMC Cancer 2023 23:961
  47. Antibody-drug conjugates (ADCs) that target human epidermal growth factor receptor 2 (HER2) are leading a new era of targeted cancer therapy. These drugs have also been associated with several fatal adverse ev...

    Authors: Zhiwen Fu, Chen Gao, Jiyi Xie, Cong Zhang, Shijun Li, Ming Gu and Chen Shi
    Citation: BMC Cancer 2023 23:960
  48. There are no standard third-line treatment options for metastatic pancreatic ductal adenocarcinoma (mPDAC). Trametinib in combination with hydroxychloroquine (HCQ) or CDK4/6 inhibitors for pancreatic adenocarc...

    Authors: Hui Tang, Yuping Ge, Tingting You, Xiaoyuan Li, Yingyi Wang, Yuejuan Cheng and Chunmei Bai
    Citation: BMC Cancer 2023 23:958

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