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  1. Despite immunotherapy’s promise in oncology, its use for sarcoma remains challenging. There are no sarcoma-specific biomarkers for immune checkpoint inhibitors (ICI). Previously, we reported our institutional ...

    Authors: Marium Husain, Dionisia Quiroga, Han Gil Kim, Scott Lenobel, Menglin Xu, Hans Iwenofu, James L. Chen, Claire Verschraegen, David Liebner and Gabriel Tinoco
    Citation: BMC Cancer 2023 23:326
  2. The survival benefit of adjuvant transarterial chemoembolization (TACE) in patients with hepatectomy for hepatocellular carcinoma (HCC) after hepatectomy remains controversial. We aimed to investigate the surv...

    Authors: Zhao Wu, Lifeng Cui, Junlin Qian, Laihui Luo, Shuju Tu, Fei Cheng, Lebin Yuan, WenJian Zhang, Wei Lin, Hongtao Tang, Xiaodong Li, Hui Li, Yang Zhang, Jisheng Zhu, Yong Li, Yuanpeng Xiong…
    Citation: BMC Cancer 2023 23:325
  3. To evaluate prognostic significance of human papillomavirus (HPV) in hypopharyngeal squamous cell carcinoma patients, and to investigate the effect of p53 and TP53 mutations on the prognosis of patients.

    Authors: Qiang Huang, Feiran Li, Mengyou Ji, Lan Lin and Chunyan Hu
    Citation: BMC Cancer 2023 23:324
  4. Colorectal cancer (CRC) is one of the most prevalent types of malignant tumours. Metastasis is the leading cause of cancer-related mortality, with lung metastases accounting for 32.9% of all metastatic CRCs. H...

    Authors: Wei Dai, Caiyao Guo, Yu Wang, Yumei Li, Renjian Xie, Junhong Wu, Baole Yao, Dong Xie, Ling He, Yingying Li, Hao Huang, Yun Wang and Shenglan Liu
    Citation: BMC Cancer 2023 23:323
  5. Essential elements have functions in tumor progression by promoting protumoral cellular processes, such as proliferation, and migration, among others. Obtaining an understanding of how these elements relate to...

    Authors: Samella Salles, Rebecca Salles, Mauro S. G. Pavão, Simone C. Cardoso and Mariana P. Stelling
    Citation: BMC Cancer 2023 23:322
  6. Ovarian cancer is one of the most lethal cancers in women because it is often diagnosed at an advanced stage. The molecular markers investigated thus far have been unsatisfactory.

    Authors: Jianxiong Li, Huaguo Liang, Wentao Xiao, Peng Wei, Hongmei Chen, Zexin Chen, Ruihui Yang, Huan Jiang and Yongli Zhang
    Citation: BMC Cancer 2023 23:321
  7. Bladder cancer is the tenth most common cancer worldwide. For patients with T1 high-grade or T2 bladder cancer, radical cystectomy is recommended. However, radical cystectomy is associated with various complic...

    Authors: Xiangwei Yang, Shiqiang Zhang, Yajiao Cui, Yamei Li, Xinyue Song and Jun Pang
    Citation: BMC Cancer 2023 23:320
  8. Numerous studies have reported the prognostic significance of the red cell distribution width (RDW) in patients with esophageal squamous cell carcinoma (ESCC), but the relationship between the perioperative ch...

    Authors: Peng Zhang, Sheng Wang, Jun-zhou Wu and Qian Song
    Citation: BMC Cancer 2023 23:319
  9. Immunotherapy has made significant advances in the treatment of extensive-stage small-cell lung cancer (ES-SCLC), but data in combination with radiotherapy are scarce. This study aims to assess the safety and ...

    Authors: Lijuan Li, Dan Yang, Yanmei Min, Anyan Liao, Jing Zhao, Leilei Jiang, Xin Dong, Wei Deng, Huiming Yu, Rong Yu, Jun Zhao and Anhui Shi
    Citation: BMC Cancer 2023 23:318
  10. Steady evolution of therapies has improved prognosis of patients with multiple myeloma (MM) over the past two decades. Yet, knowledge about survival trends and causes of death in MM might play a crucial role i...

    Authors: Christine Eisfeld, Hiltraud Kajüter, Lennart Möller, Ina Wellmann, Evgenii Shumilov and Andreas Stang
    Citation: BMC Cancer 2023 23:317
  11. Drug-induced interstitial lung disease (ILD) is not a rare adverse event in the current chemotherapy strategy for pancreatic ductal adenocarcinoma (PDAC). Thus, we aimed to find the optimal management for PDAC...

    Authors: Hiroki Irie, Rei Suzuki, Yoshinori Okubo, Hiroyuki Asama, Naoki Konno, Yuki Noguchi, Ko Watanabe, Goro Shibukawa, Hidemichi Imamura, Tadayuki Takagi, Mitsuru Sugimoto, Yuki Sato, Jun Nakamura, Tsunetaka Kato, Minami Hashimoto, Takumi Yanagita…
    Citation: BMC Cancer 2023 23:316
  12. DNA methylation is one of the most promising biomarkers in predicting the prognosis of colorectal cancer (CRC). We aimed to develop a DNA methylation biomarker that could evaluate the prognosis of CRC.

    Authors: Xuan Li, Du Cai, Yaoyi Huang, Yumo Xie, Dingcheng Shen, Ze Yuan, Xiaoxia Liu, Meijin Huang, Yanxin Luo, Huichuan Yu and Xiaolin Wang
    Citation: BMC Cancer 2023 23:315
  13. Cancer of Unknown Primary (CUP) is metastatic cancer with an unidentifiable primary tumour origin during life. It remains difficult to study the occurrence and aetiology of CUP. Hitherto, it is unclear whether...

    Authors: Karlijn E. P. E. Hermans, Fatemeh Kazemzadeh, Caroline Loef, Rob L. H. Jansen, Iris D. Nagtegaal, Piet A. van den Brandt and Leo J. Schouten
    Citation: BMC Cancer 2023 23:314
  14. Genomic alterations, including loss of function in chromosome band 11q22-23, are frequently observed in neuroblastoma, which is the most common extracranial childhood tumour. In neuroblastoma, ATM, a DNA damage r...

    Authors: Sultana Parvin, Jesmin Akter, Hisanori Takenobu, Yutaka Katai, Shunpei Satoh, Ryu Okada, Masayuki Haruta, Kyosuke Mukae, Tomoko Wada, Miki Ohira, Kiyohiro Ando and Takehiko Kamijo
    Citation: BMC Cancer 2023 23:313
  15. Pulmonary large cell neuroendocrine carcinoma (LCNEC) and small cell lung cancer (SCLC) are two types of high-grade neuroendocrine carcinomas of the lung with poor prognosis. LCNEC has not been thoroughly stud...

    Authors: Liling Huang, Yu Feng, Tongji Xie, Haohua Zhu, Le Tang and Yuankai Shi
    Citation: BMC Cancer 2023 23:312
  16. Cancer is becoming an important public health problem in Uganda. Cancer control requires surveillance of lifestyle risk factors to inform targeted interventions. However, only one national Non-Communicable Dis...

    Authors: Annet Nakaganda, Immaculate Mbarusha, Angela Spencer, Lesley Patterson, Isla Gemmell, Andrew Jones and Arpana Verma
    Citation: BMC Cancer 2023 23:311
  17. Pediatric cancer is the leading cause of disease-related death in children and the need for better therapeutic options remains urgent. Due to the limited number of patients, target and drug development for ped...

    Authors: Kaylee M. Keller, Joost Koetsier, Linda Schild, Vicky Amo-Addae, Selma Eising, Kim van den Handel, Kimberley Ober, Bianca Koopmans, Anke Essing, Marlinde L. van den Boogaard, Karin P. S. Langenberg, Natalie Jäger, Marcel Kool, Stefan Pfister, M. Emmy M. Dolman, Jan J. Molenaar…
    Citation: BMC Cancer 2023 23:310
  18. Metastatic castration-resistant prostate cancer (mCRPC) remains a therapeutic challenge and evidence for late-line treatments in real-life is limited. The present study investigates the efficacy and safety of ...

    Authors: Mustafa Asowed, Nils O Elander, Linn Pettersson, Maria Ekholm and Dimitrios Papantoniou
    Citation: BMC Cancer 2023 23:309
  19. The Neo-REGATTA study evaluated the effectiveness and safety of Docetaxel, oxaliplatin, and S-1 (DOS regimen) followed by radical resection vs. chemotherapy in advanced gastric adenocarcinoma patients with sin...

    Authors: Yuehong Cui, Yiyi Yu, Song Zheng, Jie’er Ying, Yi’an Du, Yan Wang, Xuefei Wang, Zhenbin Shen, Fenglin Liu, Minzhi Lv, Yihong Sun and Tianshu Liu
    Citation: BMC Cancer 2023 23:308
  20. Lovastatin, an HMG-CoA inhibitor and an effective cholesterol lowering drug, exhibits anti-neoplastic activity towards several types of cancer, although the underlying mechanism is still not fully understood. ...

    Authors: Jian Gao, Jifen Hu, Fang Yu, Chunlin Wang, Danmei Sheng, Wuling Liu, Anling Hu, Kunling Yu, Xiao Xiao, Yi Kuang, Eldad Zacksenhaus, Babu Gajendran and Yaacov Ben-David
    Citation: BMC Cancer 2023 23:306
  21. Recurrence and metastases are still frequent outcomes after initial tumour control in women diagnosed with breast cancer. Although therapies are selected based on tumour characteristics measured at baseline, p...

    Authors: Alexandre Prieur, Andrew Harper, Momtafin Khan, Bérengère Vire, Dominique Joubert, Léa Payen and Karen Kopciuk
    Citation: BMC Cancer 2023 23:305
  22. Colorectal cancer survivors often experience decline in physical performance and poor quality of life after surgery and during adjuvant therapies. In these patients, preserving skeletal muscle mass and high-qu...

    Authors: Inah Kim, Ji Young Lim, Sun Woo Kim, Dong Wook Shin, Hee Cheol Kim, Yoon Ah Park, Yoon Suk Lee, Jung-Myun Kwak, Seok Ho Kang, Ji Youl Lee and Ji Hye Hwang
    Citation: BMC Cancer 2023 23:304
  23. Nonerythrocytic spectrin beta 1 (SPTBN1) is an important cytoskeletal protein that involves in normal cell growth and development via regulating TGFβ/Smad signaling pathway, and is aberrantly expressed in vari...

    Authors: Wenting Tang, Qiong Shao, Zhanwen He, Xu Zhang, Xiaojuan Li and Ruohao Wu
    Citation: BMC Cancer 2023 23:303
  24. Talin-1 as a component of multi-protein adhesion complexes plays a role in tumor formation and migration in various malignancies. This study investigated Talin-1 in protein levels as a potential prognosis biom...

    Authors: Yasaman Rezaie, Fahimeh Fattahi, Baharnaz Mashinchi, Kambiz Kamyab Hesari, Sahar Montazeri, Elham Kalantari, Zahra Madjd and Leili Saeednejad Zanjani
    Citation: BMC Cancer 2023 23:302
  25. As a common malignant tumor, esophageal carcinoma (ESCA) has a low early diagnosis rate and poor prognosis. This study aimed to construct the prognostic features composed of ZNF family genes to effectively pre...

    Authors: Kunqiao Hong, Qian Yang, Haisen Yin, Na Wei, Wei Wang and Baoping Yu
    Citation: BMC Cancer 2023 23:301
  26. Physical activity and BMI have been individually associated with cancer survivorship but have not yet been studied in combinations in colorectal cancer patients. Here, we investigate individual and combined as...

    Authors: Caroline Himbert, Jennifer Ose, Biljana Gigic, Richard Viskochil, Kelly Santuci, Tengda Lin, Anjelica Ashworth, Jessica N. Cohan, Courtney L. Scaife, Jolanta Jedrzkiewicz, Victoria Damerell, Katelyn M. Atkins, Jun Gong, Matthew G. Mutch, Corey Bernadt, Seth Felder…
    Citation: BMC Cancer 2023 23:300
  27. Multiparametric magnetic resonance imaging (mMRI) is the modality of choice in the imaging of ovarian cancer (OC). We aimed to investigate the feasibility of different types of regions of interest (ROIs) in th...

    Authors: Milja Reijonen, Erikka Holopainen, Otso Arponen, Mervi Könönen, Ritva Vanninen, Maarit Anttila, Hanna Sallinen, Irina Rinta-Kiikka and Auni Lindgren
    Citation: BMC Cancer 2023 23:299
  28. We have previously reported that Toll-like receptor 3 (TLR3) acts as a suppressor gene for breast cancer initiation and progression. In this study, we evaluated the role of TLR3 in breast cancer using our origina...

    Authors: Lei Fan, Xin-Yi Sui, Xi Jin, Wen-Juan Zhang, Peng Zhou and Zhi-Ming Shao
    Citation: BMC Cancer 2023 23:298
  29. To assess construct validity and responsiveness of the Expanded Prostate Cancer Index Composite Instrument (EPIC-26) relative to the Short-Form Six-Dimension (SF-6D) and Assessment of Quality of Life 6-Dimensi...

    Authors: Norma B. Bulamu, Christine Mpundu-Kaambwa, Michael O’Callaghan and Billingsley Kaambwa
    Citation: BMC Cancer 2023 23:297
  30. The prognostic value of cytokeratin 19 fragment (CYFRA 21 − 1) and Ki67 in advanced non-small cell lung cancer (NSCLC) patients with wild-type epidermal growth factor receptor (EGFR) remains to be explored.

    Authors: Tao Li, Qi Xie, Yang-Yang Fang, Yi Sun, Xiao Ming Wang, Zhu Luo, Gui-Ling Yan, Jian-Bo He and Xiao-Qun Zheng
    Citation: BMC Cancer 2023 23:295
  31. Circulating tumor DNA (ctDNA) has been becoming a novel convenient and noninvasive method for dynamically monitoring landscape of genomic information to guild personalized cancer treatment. In this study we co...

    Authors: Jianjiang Xie, Weishen Yao, Lingxiu Chen, Wenjun Zhu, Qiang Liu, Geng Geng, Jing Fang, Yang Zhao, Li Xiao, Zhenhua Huang and Jing Zhao
    Citation: BMC Cancer 2023 23:294
  32. Skin cutaneous melanoma (SKCM) is an extremely malignant tumor and accounts for the majority of skin cancer deaths. Aspartate beta-hydroxylase domain containing 1 (ASPHD1) may participate in cancer progression...

    Authors: Shiquan Sun, Min Deng, Juan Wen, Xiaoyuan Chen, Jiaqi Xu, Yu Liu, Huanhuan Wan, Jin Wang, Leping Yan, Yong He and Yunsheng Xu
    Citation: BMC Cancer 2023 23:292
  33. Osteosarcoma (OS) is the most common malignant bone tumor with a high incidence in children and adolescents. Frequent tumor metastasis and high postoperative recurrence are the most common challenges in OS. Ho...

    Authors: Shiqi Lu, Tong Lu, Jiayu Zhang, Lunbiao Gan, Xinjie Wu, Donghui Han, Keying Zhang, Chao Xu, Shaojie Liu, Weijun Qin, Fa Yang and Weihong Wen
    Citation: BMC Cancer 2023 23:290
  34. The aims of the study were to evaluate potential differences among first-line treatment for EGFR mutant (m+) non-small cell lung cancer (NSCLC) patients with brain metastasis in China and to identify the factors ...

    Authors: Huijuan Wang, Ruyue Xing, Mengmeng Li, Mina Zhang, Chunhua Wei, Guowei Zhang, Yuanyuan Niu, Zhiyong Ma and Xiangtao Yan
    Citation: BMC Cancer 2023 23:289
  35. Endocrine-resistant breast cancers have elevated expression of XBP1, where it drives endocrine resistance by controlling the expression of its target genes. Despite the in-depth understanding of the biological...

    Authors: David Barua, Afrin Sultana, Md Nahidul Islam, Fergus Cox, Ananya Gupta and Sanjeev Gupta
    Citation: BMC Cancer 2023 23:288
  36. Visceral adiposity index (VAI) and a body shape index (ABSI) were newly developed indices for visceral fat mass. Whether they are superior to conventional obesity indices in predicting colorectal cancer (CRC) ...

    Authors: Shu Yi Wang, Wei Sen Zhang, Chao Qiang Jiang, Ya Li Jin, Tong Zhu, Feng Zhu and Lin Xu
    Citation: BMC Cancer 2023 23:286
  37. The origin recognition complex (ORC), a six-subunit DNA-binding complex, participates in DNA replication in cancer cells. Specifically in prostate cancers, ORC participates the androgen receptor (AR) regulated...

    Authors: Yuan Lin, Ying Zhang, Zhouting Tuo, Liang Gao, Demao Ding, Liangkuan Bi, Dexin Yu, Zhengmei Lv, Jiani Wang and Xin Chen
    Citation: BMC Cancer 2023 23:285
  38. As a highly heterogeneous cancer, the prognostic stratification and personalized management of hepatocellular carcinoma (HCC) are still challenging. Recently, Antigen-presenting-cells (APCs) and T-cells-infilt...

    Authors: Xiaodong Wang, Ji Chen, Lifan Lin, Yifei Li, Qiqi Tao, Zhichao Lang, Jianjian Zheng and Zhengping Yu
    Citation: BMC Cancer 2023 23:284
  39. Neoadjuvant chemotherapy (NAC) followed by surgery is the standard treatment for locally advanced esophageal squamous cell carcinoma (ESCC). Chemoradiotherapy (CRT) is an alternative treatment approach. Howeve...

    Authors: Yuki Saito, Yasuo Hamamoto, Kenro Hirata, Makoto Yamasaki, Masaya Watanabe, Tetsuya Abe, Yasuhiro Tsubosa, Yoichi Hamai, Kentaro Murakami, Takeo Bamba, Takako Yoshii, Masahiro Tsuda, Masayuki Watanabe, Masaki Ueno and Yuko Kitagawa
    Citation: BMC Cancer 2023 23:283
  40. Acapella plus active cycle of breathing technique (ACBT), external diaphragm pacemaker (EDP) plus ACBT have been shown to facilitate the recovery of functional capacity and lung function in patients suffering ...

    Authors: Xiaoxue Chen, Chuanzhen Li, Linjuan Zeng, Tiehua Rong, Peng Lin, Qinglin Wang, Zhixing Guo, Hao Long and Jiudi Zhong
    Citation: BMC Cancer 2023 23:282
  41. Residual fibroglandular breast tissue (RFGT) following a mastectomy has been claimed to be associated with the occurrence of an in-breast local recurrence (IBLR) or new primary tumor (NP). Yet, scientific evid...

    Authors: Christine Deutschmann, Christian F. Singer, Daphne Gschwantler-Kaulich, Georg Pfeiler, Carmen Leser, Pascal A. T. Baltzer, Thomas H. Helbich, Christine Kraus, Ricarda Korbatits, Alaa Marzogi and Paola Clauser
    Citation: BMC Cancer 2023 23:281
  42. Prostate cancer (PCa), one of the common malignant tumors, is the second leading cause of cancer-related deaths in men. The circadian rhythm plays a critical role in disease. Circadian disturbances are often f...

    Authors: Shuaijun Ma, Yafan Chen, Penghe Quan, Jingliang Zhang, Shichao Han, Guohui Wang, Ruochen Qi, Xiaoyan Zhang, Fuli Wang, Jianlin Yuan, Xiaojian Yang, Weijing Jia and Weijun Qin
    Citation: BMC Cancer 2023 23:280
  43. The increasing group of melanoma survivors reports multiple unmet needs regarding survivorship care (SSC). To optimise melanoma SSC, it is crucial to take into account the perspectives of oncological healthcar...

    Authors: Nadia C. W. Kamminga, Marlies Wakkee, Rianne J. De Bruin, Astrid. A. M. van der Veldt, Arjen Joosse, Suzan W. I. Reeder, Peter W. Plaisier, Tamar Nijsten and Marjolein Lugtenberg
    Citation: BMC Cancer 2023 23:278

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