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  1. The oxidative balance score (OBS) has been utilized to assess the overall pro- and antioxidant exposure status in various chronic diseases. The current meta-analysis was carried out to pool the association bet...

    Authors: Motahareh Hasani, Seyedeh Parisa Alinia, Maryam Khazdouz, Sahar Sobhani, Parham Mardi, Hanieh-Sadat Ejtahed and Mostafa Qorbani
    Citation: BMC Cancer 2023 23:1143
    Content type: Research Published on:

  2. Lung adenocarcinoma (LA) is one of the most common malignancies and is responsible for the greatest number of tumor-related deaths. Our research aimed to explore the molecular subtype signatures of LA to clari...

    Authors: Zi-Tao Liu, Jun-Ting Shen, Yu-Jie Lei, Yun-Chao Huang, Guang-Qiang Zhao, Cheng-Hong Zheng, Xi Wang, Yu-Tian Wang, Long Chen, Zi-Xuan Li, Shou-Zhuo Li, Jun Liao and Ting-Dong Yu
    Citation: BMC Cancer 2023 23:1141
    Content type: Research Published on:

  3. We aimed to investigate the efficacy and side effects of concurrent chemoradiotherapy, with or without nimotuzumab, for the treatment of locally advanced nasopharyngeal carcinoma after neoadjuvant chemotherapy.

    Authors: Zhi Yang, Quan Zuo, Rong Liu, Hui Wu, Li Xiong, Jieqi Jia and Zhibi Xiang
    Citation: BMC Cancer 2023 23:1140
    Content type: Research Published on:

  4. Calcification is a common phenomenon in both benign and malignant thyroid nodules. However, the clinical significance of calcification remains unclear. Therefore, we explored a more objective method for distin...

    Authors: Chen Chen, Yuanzhen Liu, Jincao Yao, Kai Wang, Maoliang Zhang, Fang Shi, Yuan Tian, Lu Gao, Yajun Ying, Qianmeng Pan, Hui Wang, Jinxin Wu, Xiaoqing Qi, Yifan Wang and Dong Xu
    Citation: BMC Cancer 2023 23:1139
    Content type: Research Published on:

  5. This study aims to establish and validate a new diagnosis model called P.Z.A. score for clinically significant prostate cancer (csPCa).

    Authors: Zongxin Chen, Jun Zhang, Di Jin, Xuedong Wei, Feng Qiu, Ximing Wang, Xiaojun Zhao, Jinxian Pu, Jianquan Hou, Yuhua Huang and Chen Huang
    Citation: BMC Cancer 2023 23:1138
    Content type: Research Published on:

  7. The lactate receptor GPR81 contributes to cancer development through unclear mechanisms. Here, we investigate the roles of GPR81 in three-dimensional (3D) and in vivo growth of breast cancer cells and study th...

    Authors: Kathrine Lundø, Oksana Dmytriyeva, Louise Spøhr, Eliana Goncalves-Alves, Jiayi Yao, Laia P. Blasco, Mette Trauelsen, Muthulakshmi Ponniah, Marc Severin, Albin Sandelin, Marie Kveiborg, Thue W. Schwartz and Stine F. Pedersen
    Citation: BMC Cancer 2023 23:1136
    Content type: Research Published on:

  8. Most patients diagnosed with head and neck tumor will present with locally advanced disease, requiring multimodality therapy. Bone marrow-derived mesenchymal stromal cells (BMSCs) respond to a variety of tumor...

    Authors: Hao Wang, Zhengyu Zhou, Wenchao Lin, Yechun Qian, Shifang He and Jun Wang
    Citation: BMC Cancer 2023 23:1135
    Content type: Research Published on:

  9. This study aimed to comprehensively evaluate the accuracy and effect of computed tomography (CT) and magnetic resonance imaging (MRI) based on artificial intelligence (AI) algorithms for predicting lymph node ...

    Authors: Cheng-Jie Liu, Lei Zhang, Yi Sun, Lei Geng, Rui Wang, Kai-Min Shi and Jin-Xin Wan
    Citation: BMC Cancer 2023 23:1134
    Content type: Research Published on:

  10. Psycho-oncological treatment is recommended in cancer rehabilitation as it improves fatigue, anxiety, depression, and quality of life in breast cancer patients. The aim of our study was to compare a structured...

    Authors: David Fauser, Elena Rimalis-Vogt, Johannes Mattes and Matthias Bethge
    Citation: BMC Cancer 2023 23:1133
    Content type: Research Published on:

  11. While quadruplet induction therapies deepen responses in newly diagnosed multiple myeloma patients, their impact on peripheral blood stem cell (PBSC) collection remains incompletely understood. This analysis a...

    Authors: Joseph Kauer, Emma P. Freundt, Anita Schmitt, Niels Weinhold, Elias K. Mai, Carsten Müller-Tidow, Hartmut Goldschmidt, Marc S. Raab, Katharina Kriegsmann and Sandra Sauer
    Citation: BMC Cancer 2023 23:1132
    Content type: Research Published on:

  12. Anaplastic thyroid carcinoma (ATC) was a rare malignancy featured with the weak immunotherapeutic response. So far, disorders of immunogenic cell death genes (ICDGs) were identified as the driving factors in c...

    Authors: Tong Xu, Chaozhuang Zhu, Feifeng Song, Wanli Zhang, Mengnan Yuan, Zongfu Pan and Ping Huang
    Citation: BMC Cancer 2023 23:1131
    Content type: Research Published on:

  13. Whether a transthoracic (TT) procedure by a thoracic surgeon or a transabdominal (TA) by a gastrointestinal surgeon is best for Siewert type II esophagogastric junction adenocarcinoma (EGJA) remains unknown. S...

    Authors: Hongyang Zheng, Xingmei Yin, Tiewen Pan, Xiandong Tao, Xiaolin Xu and Zhenjia Li
    Citation: BMC Cancer 2023 23:1130
    Content type: Research Published on:

  14. Duodenal papilla carcinoma (DPC) is prone to relapse even after radical pancreaticoduodenectomy (PD) (including robotic, laparoscopic and open approach). This study aimed to develop web calculators to predict ...

    Authors: Guangsheng Yu, Shuai Xu, Junjie Kong, Jingyi He and Jun Liu
    Citation: BMC Cancer 2023 23:1129
    Content type: Research Published on:

  15. The roles of low molecular mass polypeptide 2 (LMP2) and transporter-associated with antigen processing (TAP2) in tumorigenesis are controversial. Here we aimed to explore the effect of LMP2 and TAP2 on the on...

    Authors: Zhengyan Cheng, Hongbo Wang, Zewei Yang, Jiaxu Li and Xing Chen
    Citation: BMC Cancer 2023 23:1128
    Content type: Research Published on:

  16. Bladder cancer poses a significant public health burden, with high recurrence and progression rates in patients with non-muscle-invasive bladder cancer (NMIBC). Current treatment options include bladder-sparin...

    Authors: John L. Gore, Erika M. Wolff, Bryan A. Comstock, Kristin M. Follmer, Michael G. Nash, Anirban Basu, Stephanie Chisolm, Douglas B. MacLean, Jenney R. Lee, Yair Lotan, Sima P. Porten, Gary D. Steinberg, Sam S. Chang, Scott M. Gilbert, Larry G. Kessler and Angela B. Smith
    Citation: BMC Cancer 2023 23:1127
    Content type: Study Protocol Published on:

  18. The migration of lymphocytes shares many similarities in mode and mechanism with the metastasis of lung cancer tumor cells. But changes in the expression of lymphocyte migration regulation related proteins in ...

    Authors: Shuai Jin, Tianci Liu, Weiwei Wang, Tao Li, Zhefeng Liu and Man Zhang
    Citation: BMC Cancer 2023 23:1125
    Content type: Research Published on:

  19. S100A16 protein belongs to the S100 family of calcium-binding proteins, which is widely distributed in human tissues and highly conserved. S100 calcium-binding proteins possess broad biological functions, such...

    Authors: Haibin Zhang, Yongxiu Yang, Wenhu Xing, Yufeng Li and Shan Zhang
    Citation: BMC Cancer 2023 23:1124
    Content type: Research Published on:

  21. Accumulating evidence indicates that type II cystatin (CST) genes play a pivotal role in several tumor pathological processes, thereby affecting all stages of tumorigenesis and tumor development. However, the ...

    Authors: Ye-yang Chen, Bo-pei Li, Jun-fu Wang, Ye Wang, Shan-shan Luo, Ru-jing Lin, Xi-wen Liao and Jun-Qiang Chen
    Citation: BMC Cancer 2023 23:1122
    Content type: Research Published on:

  22. Ovarian cancer is a common cancer among women globally, and the assessment of lymph node metastasis plays a crucial role in the treatment of this malignancy. The primary objective of our study was to identify ...

    Authors: Yaqin Yang, Xuewei Ye, Binqian Zhou, Yang Liu, Mei Feng, Wenzhi Lv, Dan Lu, Xinwu Cui and Jianxin Liu
    Citation: BMC Cancer 2023 23:1121
    Content type: Research Published on:

  23. Ferroptosis is a newly classified form of regulated cell death with implications in various tumor progression pathways. However, the roles and mechanisms of ferroptosis-related genes in glioma remain unclear.

    Authors: Yunwen Zhang, Xinghai Wu, Jiyong Zhu, Ruibin Lu and Yian Ouyang
    Citation: BMC Cancer 2023 23:1120
    Content type: Research Published on:

  25. An Organised Cervical Cancer Screening Programme (OCCSP) was started in Poland in 2006/2007. Each woman aged 25 to 59 is eligible for a free Pap test every 3 years in OCCSP. Despite implementation of the OCCSP...

    Authors: Patrycja Glinska, Katarzyna Komerska, Beata Janik, Julia Olkowicz, Ilona Jedrzejewska, Anna Macios, Paulina Wieszczy, Michal F. Kaminski, Marc Arbyn and Andrzej Nowakowski
    Citation: BMC Cancer 2023 23:1118
    Content type: Study protocol Published on:

  26. RAS mutations affect prognosis in patients with metastatic colorectal cancer (mCRC) and have been identified as strong negative predictive markers for anti-epidermal growth factor receptor monoclonal antibody (an...

    Authors: Xiaona Lu, Yuyao Li, Yue Li, Xuemei Zhang, Jia Shi, Hai Feng, Zhuo Yu and Yueqiu Gao
    Citation: BMC Cancer 2023 23:1117
    Content type: Research Published on:

  27. Platelet distribution width (PDW), but not platelet count, was found to more comprehensively reflect platelet activity. The present study, thus, aimed to evaluate the prognostic value of PDW to lymphocyte rati...

    Authors: Zhi-Han Zhong, Lei Liang, Tian-Wei Fu, Mu-Gen Dai, Jian Cheng, Si-Yu Liu, Tai-Wei Ye, Guo-Liang Shen, Cheng-Wu Zhang, Dong-Sheng Huang and Jun-Wei Liu
    Citation: BMC Cancer 2023 23:1116
    Content type: Research Published on:

  28. Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer (NSCLC) and is the leading cause of cancer death worldwide. Its progression is characterized by genomic instability. In turn,...

    Authors: Shuyang Li, Wei Wang, Huihan Yu, Siyu Zhang, Wenxu Bi, Suling Sun, Bo Hong, Zhiyou Fang and Xueran Chen
    Citation: BMC Cancer 2023 23:1115
    Content type: Research Published on:

  29. The establishment of sister chromatid cohesion N-acetyltransferase 2 (ESCO2) is involved in the development of multiple malignancies. However, its role in hypopharyngeal carcinoma (HPC) progression remains unc...

    Authors: Juan Hu, Jing Yan, Yijie Chen, Xiaohui Li, Liu Yang, Haiyu Di, Huihui Zhang, Yewen Shi, Junjie Zhao, Yanxia Shi, Yinglong Xu, Xiaoyong Ren and Zhenghui Wang
    Citation: BMC Cancer 2023 23:1114
    Content type: Research Published on:

  30. Children with acute lymphoblastic leukaemia (ALL) experience multiple symptoms that occur in complicated patterns and negatively affect patient outcomes. To date, no systematic review has been performed on the...

    Authors: Xiaoyan Lan, Junjun Wu, Zhenling Liao, Yong Wu and Rong Hu
    Citation: BMC Cancer 2023 23:1113
    Content type: Research Published on:

  31. Follow-up of curatively treated primary breast cancer patients consists of surveillance and aftercare and is currently mostly the same for all patients. A more personalized approach, based on patients’ individ...

    Authors: A. Klaassen-Dekker, C. H. C. Drossaert, M. C. Van Maaren, A. E. Van Leeuwen-Stok, V. P. Retel, J. C. Korevaar and S. Siesling
    Citation: BMC Cancer 2023 23:1112
    Content type: Study Protocol Published on:

  32. Novel, less-invasive technologies to screen for Barrett’s esophagus (BE) may enable a paradigm shift in early detection strategies for esophageal adenocarcinoma (EAC). Understanding professionals’ perspectives...

    Authors: Jasmijn Sijben, Linda Rainey, Yonne Peters, Rebecca C. Fitzgerald, Sachin Wani, Jennifer M. Kolb, Mireille J. M. Broeders and Peter D. Siersema
    Citation: BMC Cancer 2023 23:1111
    Content type: Research Published on:

  33. Kidney renal clear cell carcinoma (KIRC) is the most common type of kidney cancer and its pathogenesis is strongly associated with VHL–HIF–VEGF signaling. SHH ligand is the upstream SHH pathway regulator, whil...

    Authors: Anna Kotulak-Chrzaszcz, Jacek Kiezun, Mateusz Czajkowski, Marcin Matuszewski, Jakub Klacz, Bartlomiej E. Krazinski, Janusz Godlewski, Zbigniew Kmiec and Piotr M. Wierzbicki
    Citation: BMC Cancer 2023 23:1110
    Content type: Research Published on:

  34. Current chemotherapy-induced peripheral neuropathy (CIPN) assessment tools mostly have poor sensitivity and weak anti-interference, so that it is sometimes difficult to provide substantive guidance for clinica...

    Authors: Zhancheng Gu, Chen Chen, Jialin Gu, Ziwei Song, Guoli Wei, Guoxiang Cai, Qijin Shu, Lingjun Zhu, Weiyou Zhu, Haibin Deng, Sheng Li, Aifei Chen, Yue Yin, Qiulan Wu, Hongyu Zhu, Guochun Li…
    Citation: BMC Cancer 2023 23:1109
    Content type: Research Published on:

  35. Ankyrin repeat domain 49 (ANKRD49) has been found to be highly expressed in multiple cancer including lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC). However, the function of ANKRD49 in the path...

    Authors: Jia Sun, Jin-rui Hu, Chao-feng Liu, Yuan Li, Wei Wang, Rong Fu, Min Guo, Hai-long Wang and Min Pang
    Citation: BMC Cancer 2023 23:1108
    Content type: Research Published on:

  36. While PD-L1 expression and neutrophil-to-lymphocyte ratio (NLR) are prognostic biomarkers for lung cancer, few studies have considered their interaction. We hypothesized that the product of PD-L1 expression (t...

    Authors: Hironobu Samejima, Kensuke Kojima, Ayako Fujiwara, Toshiteru Tokunaga, Kyoichi Okishio and Hyungeun Yoon
    Citation: BMC Cancer 2023 23:1107
    Content type: Research Published on:

  37. Researches have manifested that the disorder of iron metabolism is participated in Gastric cancer (GC), but whether iron metabolism-relevant genes (IMRGs) is related to the survival outcome of GC remain unknown.

    Authors: Xihong Liu, Junyu Ren, Ruize Zhou, Zhengqi Wen, Zhengwei Wen, Zihao Chen, Shanshan He and Hongbin Zhang
    Citation: BMC Cancer 2023 23:1106
    Content type: Research Published on:

  38. Ubiquitin-specific protease 32 (USP32) is a highly conserved gene that promotes cancer progression. However, its role in hepatocellular carcinoma (HCC) is not well understood. The aim of this project is to exp...

    Authors: Mengxi Xiu, Wenfang Bao, Jialin Wang, Jingde Chen, Yandong Li and Yanan Hai
    Citation: BMC Cancer 2023 23:1105
    Content type: Research Published on:

  39. Cervical cancer is a major health burden and the second most common cancer after breast cancer among women in Kenya. Worldwide cervical cancer constitutes 3.1% of all cancer cases. Mortality rates are greatest...

    Authors: E. Mwaliko, P. Itsura, A. Keter, Dirk De Bacquer, N. Buziba, H. Bastiaens, A. Jackie, A. Obala, V. Naanyu, P. Gichangi and M. Temmerman
    Citation: BMC Cancer 2023 23:1104
    Content type: Research Published on:

  40. Non-gestational choriocarcinoma (NGC) is a rare subtype of malignant germ cell tumour and there is no consensus on its treatment. The lack of suitable preclinical models for NGC is a challenge in drug discover...

    Authors: Yukari Oda, Kaoru Niimi, Kosuke Yoshida, Satoshi Tamauchi, Akira Yokoi, Yuko Yasui, Yuki Nishiko, Mayu Shibata, Yusuke Shimizu, Masato Yoshihara, Yoshiki Ikeda, Nobuhisa Yoshikawa, Kimihiro Nishino, Eiko Yamamoto and Hiroaki Kajiyama
    Citation: BMC Cancer 2023 23:1103
    Content type: Research Published on:

  41. Pancreatic adenocarcinoma (PAAD) is an aggressive solid tumour characterised by few early symptoms, high mortality, and lack of effective treatment. Therefore, it is important to identify new potential therape...

    Authors: Xingyi Du, Xiaoyu Yi, Xiaocui Zou, Yuan Chen, Yanhong Tai, Xuhong Ren and Xinhua He
    Citation: BMC Cancer 2023 23:1102
    Content type: Research Published on:

  42. TAB182 participates in DNA damage repair and radio-/chemosensitivity regulation in various tumors, but its role in tumorigenesis and therapeutic resistance in breast cancer remains unclear. In the current pape...

    Authors: Huan He, Shaozheng Wang, Wen Zhang, Shanshan Gao, Hua Guan and Pingkun Zhou
    Citation: BMC Cancer 2023 23:1101
    Content type: Research Published on:

  43. Accurate determination of microsatellite instability (MSI) status is critical for optimal treatment in cancer patients. Conventional MSI markers can sometimes display subtle shifts that are difficult to interp...

    Authors: Yousun Chung, Soo Kyung Nam, Ho Eun Chang, Cheol Lee, Gyeong Hoon Kang, Hye Seung Lee and Kyoung Un Park
    Citation: BMC Cancer 2023 23:1100
    Content type: Research Published on:

  45. Chemotherapy-induced peripheral neuropathy (CIPN) is a painful, dose-limiting adverse effect of commonly used chemotherapeutic agents. The purpose of this exploratory study was to evaluate the efficacy and saf...

    Authors: Sonoko Misawa, Tadamichi Denda, Sho Kodama, Takuji Suzuki, Yoichi Naito, Takahiro Kogawa, Mamoru Takada, Tomoki Suichi, Kazuhito Shiosakai and Satoshi Kuwabara
    Citation: BMC Cancer 2023 23:1098
    Content type: Research Published on:

  46. Colorectal cancer (CRC) is one of the most common malignancies worldwide. Immunotherapy targeting the programmed death protein 1(PD-1) and its ligand (PD-L1), is a promising treatment option for many cancers, ...

    Authors: Yuying Dong, Mingming Zheng, Xiaoxuan Wang, Chenyue Yu, Tiantian Qin and Xuning Shen
    Citation: BMC Cancer 2023 23:1097
    Content type: Research Published on:

  47. Stroke is a rare but fatal complication of advanced cancer with Trousseau syndrome, especially as initial symptoms. Here, we report the clinical characteristics, treatment, and prognosis of patients with non-s...

    Authors: Weiping Hong, Tongtong Zhang, Changguo Shan, Hainan Li, Tao Lin, Da Liu, Junjie Zhen, Juan Li, Mingyao Lai, Zhaoming Zhou, Cheng Zhou, Meijuan Zhou, Minghua Wang, Linbo Cai and Lei Wen
    Citation: BMC Cancer 2023 23:1096
    Content type: Research Published on:

  49. Gut microbiota (GM) comprises a vast and diverse community of microorganisms, and recent studies have highlighted the crucial regulatory roles of various GM and their secreted metabolites in pancreatic cancer ...

    Authors: Zhichen Jiang, Yiping Mou, Huiju Wang, Li Li, Tianyu Jin, He Wang, Mingyang Liu and Weiwei Jin
    Citation: BMC Cancer 2023 23:1091
    Content type: Research Published on:

  50. Cancer stem cells form a rare cell population in tumors that contributes to metastasis, recurrence and chemoresistance in cancer patients. Circular RNAs (circRNAs) are post-transcriptional regulators of gene e...

    Authors: Vimalan Rengganaten, Chiu-Jung Huang, Mong-Lien Wang, Yueh Chien, Ping-Hsing Tsai, Yuan-Tzu Lan, Hooi Tin Ong, Shih-Hwa Chiou and Kong Bung Choo
    Citation: BMC Cancer 2023 23:1088
    Content type: Research Published on:

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