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  1. Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide. Inhibitor of kappa B kinase interacting protein (IKBIP) has been reported to promote glioma progression, but its role in o...

    Authors: Jiannan Hu, Chuanjing Dai, Zhaoji Ding, Yixiao Pan, Lingxiao Lu, Jiaqian Bao and Jingmin Zheng
    Citation: BMC Cancer 2024 24:759
    Content type: Research Published on:

  4. Diffuse midline glioma (DMG), H3 K27M-mutant is a type of diffuse high-grade glioma that occurs in the brain midline carrying an extremely poor prognosis under the best efforts of surgery, radiation, and other...

    Authors: Yu-An Li, Chuan Zhao, Jing-Jing Ge, Cheng Li, Feng-Jun Xue, Shao-Pei Qi, Chi Zhao, Chen-Chen Kong and Jun-Ping Zhang
    Citation: BMC Cancer 2024 24:754
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2024 24:829

  5. Investigating novel therapeutic strategies for colorectal cancer (CRC) is imperative. However, there is limited research on the use of drugs to target peripheral blood immune cells in this context. To address ...

    Authors: Runze Huang, Xin Jin, Ziting Jiang, Yixiu Wang, Yibin Wu, Lu Wang and Weiping Zhu
    Citation: BMC Cancer 2024 24:753
    Content type: Research Published on:

  6. Among gynaecological malignancies, endometrial cancer (EC) is the most prevalent type of uterine cancer affecting women. This study explored the proteomic profiles of plasma samples obtained from EC patients, ...

    Authors: Khalid Akkour, Ibrahim O Alanazi, Assim A Alfadda, Afshan Masood, Hani Alhalal, Salini Scaria Joy, Ali Bassi, Eman Alshehri, Moudi A Alwehaibi, Maria Arafah and Hicham Benabdelkamel
    Citation: BMC Cancer 2024 24:752
    Content type: Research Published on:

  7. Despite the availability of effective vaccines, human papillomavirus (HPV) vaccine uptake remains low in most resource-limited settings including Nigeria. Mobile health technology (mHealth) has the potential t...

    Authors: Kehinde S. Okunade, Adebola A. Adejimi, Temitope V. Adekanye, Matthew J. Allsop, Hameed Adelabu, Olufemi Thomas-Ogodo, Tonia C. Onyeka, Teniola Lawanson, Godwin O. Akaba, Omolola Salako, Rose I. Anorlu and Jonathan S. Berek
    Citation: BMC Cancer 2024 24:751
    Content type: Study Protocol Published on:

  9. To explore challenges of liquid-based cytology (LBC) specimens for next-generation sequencing (NGS) in lung adenocarcinoma and evaluate the efficacy of targeted therapy.

    Authors: Xiaoyue Xiao, ZiHan Sun, Shuo Liang, Weihua Li, HuiQin Guo, Huan Zhao, LinLin Zhao, HaiYue Ma, Yue Sun, Cong Wang, XinXiang Chang and ZhiHui Zhang
    Citation: BMC Cancer 2024 24:749
    Content type: Research Published on:

  10. Thymic epithelial tumors (TETs) are rare neoplasms often associated with immune-related disorders. Patients with Good’s syndrome (GS), an adult-acquired TET-related immunodeficiency, are at a high risk of mort...

    Authors: Erica Pietroluongo, Annarita Peddio, Pietro De Placido, Marianna Tortora, Margaret Ottaviano, Monica Gelzo, Gustavo Cernera, Maria Foggia, Antonio Riccardo Buonomo, Biagio Pinchera, Emanuela Zappulo, Simona Mercinelli, Letizia Cattaneo, Alessia Sardanelli, Giulio Viceconte, Riccardo Scotto…
    Citation: BMC Cancer 2024 24:748
    Content type: Research Published on:

  11. The prognosis of patients with Relapsed/Refractory Osteosarcoma (R/R OS) remains dismal without an agreement on systemic therapy. The use of High-Dose Ifosfamide (14 g/sqm) with an external pump in outpatient ...

    Authors: Elisa Tirtei, Anna Campello, Veronica Sciannameo, Sebastian Dorin Asaftei, Cristina Meazza, Giovanna Sironi, Alessandra Longhi, Toni Ibrahim, Angela Tamburini, Luca Coccoli, Fanj Crocco, Celeste Cagnazzo, Elvira De Luna, Paola Quarello, Paola Berchialla and Franca Fagioli
    Citation: BMC Cancer 2024 24:747
    Content type: Research Published on:

  12. Basement membrane (BM) is an important component of the extracellular matrix, which plays an important role in the growth and metastasis of tumor cells. However, few biomarkers based on BM have been developed ...

    Authors: Xuezhou Zhang, Baoan Hong, Hongwei Li, Jiahui Zhao, Mingchuan Li, Dechao Wei, Yongxing Wang and Ning Zhang
    Citation: BMC Cancer 2024 24:746
    Content type: Research Published on:

  13. As gastric cancer patients aged ≥ 85 years have a short life expectancy and often die from other diseases such as pneumonia, indications for surgery are controversial. In this study, we retrospectively analyze...

    Authors: Shunji Endo, Masaharu Higashida, Kei Furuya, Shuya Yano, Toshimasa Okada, Kazuhiko Yoshimatsu, Yoshinori Fujiwara and Tomio Ueno
    Citation: BMC Cancer 2024 24:745
    Content type: Research Published on:

  14. Tumor hypoxia is associated with prostate cancer (PCa) treatment resistance and poor prognosis. Pimonidazole (PIMO) is an investigational hypoxia probe used in clinical trials. A better understanding of the cl...

    Authors: Xinpei Ci, Sujun Chen, Rui Zhu, Mojgan Zarif, Rahi Jain, Wangyuan Guo, Matthew Ramotar, Linsey Gong, Wenjie Xu, Olivia Singh, Sheila Mansouri, Gelareh Zadeh, Gong-Hong Wei, Wei Xu, Robert Bristow, Alejandro Berlin…
    Citation: BMC Cancer 2024 24:744
    Content type: Research Published on:

  15. Breast cancer is a prevalent cancer characterized by its aggressive nature and potential to cause mortality among women. The rising mortality rates and women’s inadequate perception of the disease’s severity i...

    Authors: Sepideh Mashayekh-Amiri, Mohammad Asghari Jafarabadi, Mina Hosseinzadeh, Elham seyed Kanani and Mojgan Mirghafourvand
    Citation: BMC Cancer 2024 24:743
    Content type: Research Published on:

  16. Nasopharyngeal adenoid cystic carcinoma (NACC) is a relatively rare salivary gland tumor that is generally associated with poor outcomes. High-dose radiotherapy is a key treatment for patients with NACC. This ...

    Authors: Weixu Hu, Jiyi Hu, Qingting Huang, Jing Gao, Haojiong Zhang and Lin Kong
    Citation: BMC Cancer 2024 24:742
    Content type: Research Published on:

  17. Sarcopenia is characterized by reduced skeletal muscle volume and is a condition that is prevalent among elderly patients and associated with poor prognosis as a comorbidity in malignancies. Given the aging po...

    Authors: Makoto Takahashi, Kazuhiro Sakamoto, Yosuke Kogure, Shuko Nojiri, Yuki Tsuchiya, Kumpei Honjo, Masaya Kawai, Shun Ishiyama, Kiichi Sugimoto, Kunihiko Nagakari and Yuichi Tomiki
    Citation: BMC Cancer 2024 24:741
    Content type: Research Published on:

  18. Using the preoperative pan-immune-inflammation value (PIV) and the monocyte to high-density lipoprotein ratio (MHR) to reflect inflammation, immunity, and cholesterol metabolism, we aim to develop and visualiz...

    Authors: Qinghua Liu, Haohao Wang, Qingjie Chen, Ruiying Luo and Changjiang Luo
    Citation: BMC Cancer 2024 24:740
    Content type: Research Published on:

  19. A growing number of expression quantitative trait loci (eQTLs) have been found to be linked with tumorigenesis. In this article, we employed integrated Mendelian randomization (MR) analyses to identify novel s...

    Authors: Qiming Wang, Shaopeng Chen, Gang Wang, Tielong Zhang and Yulong Gao
    Citation: BMC Cancer 2024 24:739
    Content type: Research Published on:

  21. Bladder cancer (BC) is among the most prevalent malignant urothelial tumors globally, yet the prognosis for patients with muscle-invasive bladder cancer (MIBC) remains dismal, with a very poor 5-year survival ...

    Authors: Hao Meng, Rui Yang, Qianqian Lin, Wenqi Du, Zheng Chu, Yaxin Cao, Mengxiang Du, Yazhen Zhao, Jiheng Xu, Ziyi Yang, Xiaomin Xie, Lijiong He and Chuanshu Huang
    Citation: BMC Cancer 2024 24:737
    Content type: Research Published on:

  22. Glioblastoma (GBM) is the most common and aggressive primary brain cancer. The treatment of GBM consists of a combination of surgery and subsequent oncological therapy, i.e., radiotherapy, chemotherapy, or the...

    Authors: Radek Lakomý, Martina Lojová, Lenka Souckova, Ludmila Hynkova, Katerina Polachova, Jiri Vasina, Regina Demlová, Alexandr Poprach, Jiri Sana, Tomas Prochazka, Martin Smrcka, Pavel Fadrus, Radim Jancalek, Iveta Selingerova, Renata Belanova, Pavel Slampa…
    Citation: BMC Cancer 2024 24:736
    Content type: Study Protocol Published on:

  23. The addition of pertuzumab (P) to trastuzumab (H) and standard chemotherapy (CT) as neoadjuvant treatment (NaT) for patients with HER2 + breast cancer (BC), has shown to increase the pathological complete resp...

    Authors: Fabio Canino, Monica Barbolini, Ugo De Giorgi, Tommaso Fontana, Valeria Gaspari, Caterina Gianni, Lorenzo Gianni, Antonio Maestri, Santino Minichillo, Luca Moscetti, Antonella Mura, Stefania Vittoria Luisa Nicoletti, Claudia Omarini, Rachele Pagani, Samanta Sarti, Angela Toss…
    Citation: BMC Cancer 2024 24:735
    Content type: Research Published on:

  24. The role of familial influence in chronic myeloid leukaemia (CML) occurrence is less defined. Previously, we conducted a study to determine the prevalence of harbouring BCR::ABL1 in our local adult normal populat...

    Authors: Jew Win Kuan, Anselm Ting Su, Sai-Peng Sim and Siow Phing Tay
    Citation: BMC Cancer 2024 24:734
    Content type: Research Published on:

  25. Checkpoint inhibitors (CPIs) are widely used in cancer treatment, with transformative impacts on survival. They nonetheless carry a significant risk of toxicity in the form of immune-related adverse events (Ir...

    Authors: Abigail Gault, Linda Hogarth, Kristian C Williams, Alastair Greystoke, Neil Rajan, Ally Speight, Christopher A Lamb, Alison Bridgewood, Lisa-Jayne Brown-Schofield, Fiona Rayner, John D Isaacs, Jérémie Nsengimana, Christopher J Stewart, Amy E Anderson, Ruth Plummer and Arthur G Pratt
    Citation: BMC Cancer 2024 24:733
    Content type: Study Protocol Published on:

  26. Considering the age relevance of prostate cancer (PCa) and the involvement of the cGAS-STING pathway in aging and cancer, we aim to classify PCa into distinct molecular subtypes and identify key genes from the...

    Authors: Jie Yang, Zihan Xu, Weitao Zheng, Yifan Li, Qiang Wei and Lu Yang
    Citation: BMC Cancer 2024 24:732
    Content type: Research Published on:

  28. Oral cavity squamous cell carcinoma (OCSCC) is the most common pathological type in oral tumors. This study intends to construct a novel prognostic nomogram model based on China populations for these resectabl...

    Authors: Xue-Lian Xu, Jin-Hong Xu, Jia-Qi He, Yi-Hao Li and Hao Cheng
    Citation: BMC Cancer 2024 24:730
    Content type: Research Published on:

  29. Chondroitin sulfate proteoglycan 4 pseudogene 12 (CSPG4P12) has been implicated in the pathogenesis of various cancers. This study aimed to evaluate the association of the CSPG4P12 polymorphism with esophageal sq...

    Authors: Hongxue Xu, Zhenbang Yang, Wenqian Hu, Xianlei Zhou, Zhi Zhang and Xuemei Zhang
    Citation: BMC Cancer 2024 24:729
    Content type: Research Published on:

  30. Circular RNA (circRNAs) have been found to play major roles in the progression of colorectal cancer (CRC). However, the functions of circ_0008345 (transcribed by PTK2) in regulating CRC development remain unde...

    Authors: Chaofeng Hou, Jinbo Liu, Junwei Liu, Danjie Yao, Fang Liang, Congpeng Qin and Zhiyong Ma
    Citation: BMC Cancer 2024 24:728
    Content type: Research Published on:

  31. The Naples Prognostic Score (NPS), integrating inflammatory and nutritional biomarkers, has been reported to be associated with the prognosis of various malignancies, but there is no report on intrahepatic cho...

    Authors: Cheng-Fei Du, Zhen-Yu Gao, Zhu-Ding Xu, Zheng-Kang Fang, Zi-Chen Yu, Zhe-Jin Shi, Kai-Di Wang, Wen-Feng Lu, Xiao-Kun Huang, Lei Jin, Tian-Wei Fu, Guo-Liang Shen, Jun-Wei Liu, Cheng-Wu Zhang, Dong-Sheng Huang and Lei Liang
    Citation: BMC Cancer 2024 24:727
    Content type: Research Published on:

  32. Polysaccharopeptide (PSP) is a potential active component in traditional Chinese medicine because of its anticancer effects on a variety of cancer cells and as immune enhancers of the immune system. Previous s...

    Authors: Cuixiang Xu, Lijun Sun, Huxia Wang, Jingying Sun, Yangmeng Feng, Xingguang Wang and Zhangjun Song
    Citation: BMC Cancer 2024 24:726
    Content type: Research Published on:

  33. Lymph node metastasis (LNM) is associated with worse prognosis in bladder urothelial carcinoma (BUC) patients. This study aimed to develop and validate machine learning (ML) models to preoperatively predict LN...

    Authors: Junjie Ji, Tianwei Zhang, Ling Zhu, Yu Yao, Jingchang Mei, Lijiang Sun and Guiming Zhang
    Citation: BMC Cancer 2024 24:725
    Content type: Research Published on:

  34. Tumor immune infiltration leads to poor prognosis of gastric cancer patients and seriously affects the life quality of gastric cancer patients. This study was based on bioinformatics to screen prognostic bioma...

    Authors: MeiHong Yu, Jingxuan Peng, Yanxu Lu, Sha Li and Ke Ding
    Citation: BMC Cancer 2024 24:724
    Content type: Research Published on:

  35. Among the 10% of pancreatic cancers that occur in a familial context, around a third carry a pathogenic variant in a cancer predisposition gene. Genetic studies of pancreatic cancer predisposition are limited ...

    Authors: Sofie Joris, Philippe Giron, Catharina Olsen, Sara Seneca, Alexander Gheldof, Shula Staessens, Rajendra Bahadur Shahi, Sylvia De Brakeleer, Erik Teugels, Jacques De Grève and Frederik J. Hes
    Citation: BMC Cancer 2024 24:723
    Content type: Research Published on:

  36. Childhood, adolescent, and young adult (CAYA) cancer survivors, at risk for late effects, including cancer-related fatigue, cardiovascular issues, and psychosocial challenges, may benefit from interventions st...

    Authors: Eline Bouwman, Iridi Stollman, Joyce Wilbers, Joyce J. M. Claessens, Dick Johan van Spronsen, Annet Bongaerts, Dionne Breij, Nicole M. A. Blijlevens, Hans Knoop, Rosella P. M. G. Hermens and Jacqueline J. Loonen
    Citation: BMC Cancer 2024 24:722
    Content type: Research Published on:

  37. Pneumonia and lung cancer are both major respiratory diseases, and observational studies have explored the association between their susceptibility. However, due to the presence of potential confounders and re...

    Authors: Lujia Song, Dongsheng Wu, Jiayang Wu, Jiexi Zhang, Weimin Li and Chengdi Wang
    Citation: BMC Cancer 2024 24:721
    Content type: Research Published on:

  38. To use data from the Global Burden of Disease (GBD) Study 2019 to report the global, regional and national rates and trends of deaths incidence, prevalence, disability-adjusted life years (DALYs) for Nasophary...

    Authors: Guoxin Huang, Yaojie Wang, Bingqing Qin, Jing Zeng, Huazhang tan, Dongdong Zhang and Qiuyang Wang
    Citation: BMC Cancer 2024 24:720
    Content type: Research Published on:

  39. Evaluation of human epidermal growth factor receptor 2 (HER2) overexpression caused by erb-b2 receptor tyrosine kinase 2 (ERBB2) amplification (AMP) by immunohistochemistry (IHC) and fluorescence in situ hybridiz...

    Authors: Hiroshi Ichikawa, Kenji Usui, Masaki Aizawa, Yoshifumi Shimada, Yusuke Muneoka, Yosuke Kano, Mika Sugai, Kazuki Moro, Yuki Hirose, Kohei Miura, Jun Sakata, Hiroshi Yabusaki, Satoru Nakagawa, Takashi Kawasaki, Hajime Umezu, Shujiro Okuda…
    Citation: BMC Cancer 2024 24:719
    Content type: Research Published on:

  41. To compare the efficacy and safety of transcatheter arterial chemoembolization (TACE) combined Lenvatinib plus Camrelizumab (TLC) in unresectable hepatocellular carcinoma (uHCC) with those of TACE alone .

    Authors: Zhihong Tang, Tao Bai, Tao Wei, Xiaobo Wang, Jie Chen, Jiazhou Ye, Shangqi Li, Meng Wei, Xingzhi Li, Youzhi Lin, Juan Tang, Lequn Li and Feixiang Wu
    Citation: BMC Cancer 2024 24:717
    Content type: Research Published on:

  42. To compare the diagnostic performance of the Node-RADS scoring system and lymph node (LN) size in preoperative LN assessment for rectal cancer (RC), and to investigate whether the selection of size as the prim...

    Authors: Yue Niu, Lu Wen, Yanhui Yang, Yi Zhang, Yi Fu, Qiang Lu, Yu Wang, Xiao Yu and Xiaoping Yu
    Citation: BMC Cancer 2024 24:716
    Content type: Research Published on:

  43. Resistance to immune checkpoint inhibitors (ICIs) represents a major unmet medical need in non-small cell lung cancer (NSCLC) patients. Vascular endothelial growth factor (VEGF) inhibition may reverse a suppre...

    Authors: Bo Zhang, Hongyu Liu, Chunlei Shi, Zhiqiang Gao, Runbo Zhong, Aiqin Gu, Tianqing Chu, Huimin Wang, Liwen Xiong, Wei Zhang, Xueyan Zhang, Bo Yan, Jiajun Teng, Weimin Wang, Hao Bai, Rong Qiao…
    Citation: BMC Cancer 2024 24:715
    Content type: Research Published on:

  44. Our study aims to explore the relationship, shared gene signature, and the underlying mechanisms that connect rheumatoid arthritis (RA) to colorectal cancer (CRC).

    Authors: Zhi-Qing Zhan, Ze-Min Huang, Qi-Wen Lan, Yu-Hua Luo, Jia-Xin Li, Ya-Fang Zheng, Ying-Zhou Chen, Pei-Zhen Chen, Tian-Ye Luo, Baoqing Sun and Zhangkai J Cheng
    Citation: BMC Cancer 2024 24:714
    Content type: Research Published on:

  46. Female gynecological cancers represent a serious public health problem, with 1,398,601 new diagnoses and 671,875 deaths per year worldwide. Antipsychotics are often used in psychiatric disorders, including sch...

    Authors: Francisco Cezar Aquino de Moraes, Renan Yuji Ura Sudo, Maria Eduarda Cavalcanti Souza, Marianne Rodrigues Fernandes and Ney Pereira Carneiro dos Santos
    Citation: BMC Cancer 2024 24:712
    Content type: Research Published on:

  47. Inflammatory factors have increasingly become a more cost-effective prognostic indicator for gastric cancer (GC). The goal of this study was to develop a prognostic score system for gastric cancer patients bas...

    Authors: Shaobo Zhang, Hongxia Xu, Wei Li, Jiuwei Cui, Qingchuan Zhao, Zengqing Guo, Junqiang Chen, Qinghua Yao, Suyi Li, Ying He, Qiuge Qiao, Yongdong Feng, Hanping Shi and Chunhua Song
    Citation: BMC Cancer 2024 24:711
    Content type: Research Published on:

  48. Papillary thyroid carcinoma (PTC) is globally prevalent and associated with an increased risk of lymph node metastasis (LNM). The role of cancer-associated fibroblasts (CAFs) in PTC remains unclear.

    Authors: Yixian Wang, Xin Li, Qingwei Gang, Yinde Huang, Mingyu Liu, Han Zhang, Shikai Shen, Yao Qi and Jian Zhang
    Citation: BMC Cancer 2024 24:710
    Content type: Research Published on:

  49. Pancreatic cancer, predominantly characterized by ductal adenocarcinoma (PDAC) accounts for 90% of cases and is the fourth leading cause of cancer-related deaths globally. Its incidence is notably increasing. ...

    Authors: Thomas Bardol, Antoine M. Dujon, Valerie Taly, Catherine Dunyach-Remy, Jean-Philippe Lavigne, Bruno Costa-Silva, Keerthi Kurma, Zahra Eslami-S, Laure Cayrefourcq, Cindy Canivet, Fabrice Muscari, Barbara Bournet and Catherine Alix-Panabières
    Citation: BMC Cancer 2024 24:709
    Content type: Study Protocol Published on:

  50. Novel antibody-drug conjugates (ADCs) drugs present a promising anti-cancer treatment, although survival benefits for HER2-positive advanced breast cancer (BC) remain controversial. The aim of this meta-analys...

    Authors: Zian Kang, Yuqing Jin, Huihui Yu, Su Li and Yingjie Qi
    Citation: BMC Cancer 2024 24:708
    Content type: Research Published on:

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