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  1. Although malnutrition is common in cancer patients, its molecular mechanisms has not been fully clarified. This study aims to identify significantly differential metabolites, match the corresponding metabolic ...

    Authors: Liang Fu, Lixin Song, Xi Zhou, Lin Chen, Lushan Zheng, Dandan Hu, Sha Zhu, Yanting Hu, Daojun Gong, Chun-Liang Chen, Xianghong Ye and Shian Yu
    Citation: BMC Cancer 2024 24:1195
    Content type: Research Published on:

  2. Histone acetylation plays a critical role in the progression of acute myeloid leukemia (AML). This study aimed to explore the prognostic significance and biological implications of histone acetylation-related ...

    Authors: Xiaojuan Guo, Guinian Huang, Dafa Qiu, Huiqing He, Xiaomin Niu, Ziwen Guo and Yongbin Ye
    Citation: BMC Cancer 2024 24:1189
    Content type: Research Published on:

  3. This study analyzed and discussed the characteristics of peripheral blood lymphocytes (PBLs) in patients with endometrial carcinoma (EC) to explore the PBLs’ clinical application value.

    Authors: Yingyu Tian, Yuchun Zhang, Xi Tang, Jing Liu, Qin Huang, Yi Chen, Qian Zhan and Hui Wang
    Citation: BMC Cancer 2024 24:1184
    Content type: Research Published on:

  4. Patients with small-cell lung cancer (SCLC) have few treatment options and dismal overall survival (OS) after failed platinum-based chemotherapy.

    Authors: Wei Wang, Guixian Wu, Wujun Luo, Ling Lin, Chao Zhou, Guifei Yao, Meifang Chen, Xiaomai Wu, Ziran Chen, Junhui Ye, Haihua Yang and Dongqing Lv
    Citation: BMC Cancer 2024 24:1182
    Content type: Research Published on:

  5. Comprehensive analysis of clinical evidence for breast cancer adipogenesis with prognosis is lacking. This study aims to consolidate the latest evidence on the relationship between adipogenesis and breast canc...

    Authors: Shihang Hu, Sze Keong Tey and Ava Kwong
    Citation: BMC Cancer 2024 24:1181
    Content type: Research Published on:

  6. Lung cancer (LC), a paramount global life-threatening condition causing significant mortality, is most commonly characterized by its subtype, lung adenocarcinoma (LUAD). Concomitant with LC, pulmonary fibrosis...

    Authors: Haiyang Li, Xing Fu, Mingtao Liu, Jiaxi Chen, Wenhan Cao, Zhiman Liang, Zhangkai J. Cheng and Baoqing Sun
    Citation: BMC Cancer 2024 24:1178
    Content type: Research Published on:

  7. Long noncoding RNAs (lncRNAs) are crucial regulators of biological processes such as transcription interference and activation, chromatin remodeling, and mRNA translation. Uncontrolled gene expression could re...

    Authors: Neveen A. Hussein, Samia A. Ebied, Abdel Aziz M. Belal, Mohamad A. Ahmad and El Sayed A. Weheida
    Citation: BMC Cancer 2024 24:1175
    Content type: Research Published on:

  8. Salivary duct carcinoma (SDC) is a rare and aggressive subtype of salivary gland cancer, frequently associated with incurable recurrences and distant metastases (R/M). Proliferation of SDC relies on androgen r...

    Authors: Jetty A. M. Weijers, Gerald W. Verhaegh, G. Lassche, Adriana C. H. van Engen-van Grunsven, Chantal M. L. Driessen, Nielka P. van Erp, Marianne A. Jonker, Jack A. Schalken and Carla M. L. van Herpen
    Citation: BMC Cancer 2024 24:1174
    Content type: Study Protocol Published on:

  9. Exosomes are closely associated with different aspects of tumor-progression in patients with head and neck squamous cell carcinoma (HNSCC), such as angiogenesis or immune regulation. As extracellular vesicles ...

    Authors: Marie-Nicole Theodoraki, Diana Huber, Linda Hofmann, Lotte Werner, Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lutz Schütt, Cornelia Brunner, Reinhard Depping, Thomas K. Hoffmann, Karl-Ludwig Bruchhage and Ralph Pries
    Citation: BMC Cancer 2024 24:1173
    Content type: Research Published on:

  10. In the era of tyrosine kinase inhibitor (TKI) treatment, the progression of chronic myeloid leukemia (CML) remains a significant clinical challenge, and genetic biomarkers for the early identification of CML p...

    Authors: Jingwei Zhao, Guiran Wang, Guiling Yan, Mengting Zheng, Hongshuang Li, Yuanyuan Bai, Xiaoqun Zheng and Zhanguo Chen
    Citation: BMC Cancer 2024 24:1172
    Content type: Research Published on:

  11. The risk of cervical cancer progression in high-risk human papillomavirus (HR-HPV)-positive women is associated with cervical lesion severity and molecular heterogeneity. Classification systems based on p16 an...

    Authors: Haijun Luo, Yixiang Lian, Hong Tao, Yan Zhao, Zhigan Wang, Jing Zhou, Zirong Zhang and Shali Jiang
    Citation: BMC Cancer 2024 24:1171
    Content type: Research Published on:

  12. To retrospectively explore the clinical significance of radiotherapy to the distant metastatic lymph nodes (cervical/ clavicular/ mediastinal et al.) in metastatic cervical cancer. Hereinto, these cervicothora...

    Authors: Chi Fang, Suping Liu, Jie Xia, Xiaohua Wu, Jun Zhu and Guihao Ke
    Citation: BMC Cancer 2024 24:1170
    Content type: Research Published on:

  14. Tri-combination therapy based on hepatic arterial infusion chemotherapy (HAIC) of infusion fluorouracil, leucovorin, and oxaliplatin (FOLFOX-HAIC) plus immune checkpoint inhibitors (ICIs) and tyrosine kinase i...

    Authors: Liyang Sun, Zhiwen Hu, Wa Xie, Zhenyun Yang, Huilan Zeng, Yaojun Zhang, Minshan Chen, Dandan Hu, Zhongguo Zhou and Yangxun Pan
    Citation: BMC Cancer 2024 24:1168
    Content type: Research Published on:

  15. Metastatic pancreatic ductal adenocarcinoma (mPDAC) patients have very poor prognosis highlighting the urgent need of novel treatments. In this regard, repurposing non-oncology already-approved drugs might be ...

    Authors: Alfredo Budillon, Alessandra Leone, Eugenia Passaro, Lucrezia Silvestro, Francesca Foschini, Federica Iannelli, Maria Serena Roca, Marina Macchini, Francesca Bruzzese, Maria Laura Garcia Bermejo, Mercedes Rodriguez Garrote, Giampaolo Tortora, Michele Milella, Michele Reni, Claudia Fuchs, Eve Hewitt…
    Citation: BMC Cancer 2024 24:1167
    Content type: Study Protocol Published on:

  16. The prognosis of breast cancer patients with visceral metastasis (VM) is significantly worse than that of patients without VM. We aimed to evaluate EZH2 (enhancer of zeste homolog 2) mutation as a biomarker as...

    Authors: Fan Wu, Nani Li, Xiufeng Wu, Mulan Chen, Weiwei Huang, Xinhua Chen, Yi Hong, Lili Wang, Kan Chen, Lin Lin, Minjin You and Jian Liu
    Citation: BMC Cancer 2024 24:1166
    Content type: Research Published on:

  17. Cancer-associated fibroblasts (CAFs), as key cell populations in the tumor microenvironment (TME), play a crucial role in tumor regulation. Previous studies on a prognostic signature of 8 CAF-related genes in ...

    Authors: Lei Dong, Yumei Li, Xiaoyu Song, Caiyu Sun and Xicheng Song
    Citation: BMC Cancer 2024 24:1165
    Content type: Research Published on:

  18. The intricate interplay of cancer stem cell plasticity, along with the bidirectional transformation between epithelial-mesenchymal states, introduces further intricacy to offer insights into newer therapeutic ...

    Authors: Ankit Mathur, Chanchal Bareja, Milky Mittal, Anjali Singh and Daman Saluja
    Citation: BMC Cancer 2024 24:1164
    Content type: Research Published on:

  19. Breast cancer (BC) is the most common cancer in women, and its progression is closely related to the phenomenon of anoikis. Anoikis, the specific programmed death resulting from a lack of contact between cells...

    Authors: Mingzheng Tang, Yao Rong, Xiaofeng Li, Haibang Pan, Pengxian Tao, Zhihang Wu, Songhua Liu, Renmei Tang, Zhilong Liu and Hui Cai
    Citation: BMC Cancer 2024 24:1163
    Content type: Research Published on:

  20. Despite a high incidence of colorectal carcinoma, data regarding genetic aberrations in colorectal carcinoma (CRC) patients in Pakistan is scarce. This study aimed to determine the frequency of BRAFV600E mutation...

    Authors: Sobia Hassan, Talat Mirza, Ambrina Khatoon, Uzma Bukhari, Fouzia Shaikh and Asad Karim
    Citation: BMC Cancer 2024 24:1162
    Content type: Research Published on:

  21. Many studies have explored the clinicopathological features and prognosis between colorectal mucinous adenocarcinoma (MAC) and adenocarcinoma (AC) and have given different results. This meta-analysis summarize...

    Authors: Xiao Wang, Haoran Wang, Haoqing He, Kai Lv, Wenguang Yuan, Jingbo Chen and Hui Yang
    Citation: BMC Cancer 2024 24:1161
    Content type: Research Published on:

  22. To investigate the values of apparent diffusion coefficient (ADC) for the treatment response evaluation in pancreatic cancer (PC) patients receiving neoadjuvant therapy (NAT).

    Authors: Yufei Chen, Chao Ma, Panpan Yang, Kuanzheng Mao, Yisha Gao, Luguang Chen, Zhen Wang, Yun Bian, Chengwei Shao and Jianping Lu
    Citation: BMC Cancer 2024 24:1160
    Content type: Research Published on:

  23. eHealth may help closing gaps in the long-term follow-up care of former young age cancer patients. While its introduction to medical aftercare appears promising, it also faces obstacles in the course of its im...

    Authors: Tjorven Stamer, Pia Traulsen, Johannes Rieken, Teresa Schmahl, Ingo Menrath and Jost Steinhäuser
    Citation: BMC Cancer 2024 24:1159
    Content type: Research Published on:

  24. Post-translational modification pathway of protein ubiquitination is intricately associated with tumorigenesis. We previously reported elevated ubiquitin-conjugating enzyme 2T (UBE2T) as an independent risk fa...

    Authors: Yujie Deng, Xiaohui Chen, Xuzheng Chen, Chuanzhong Huang, Zhiguang Zhang, Zhenguo Xu, Xiurong Wang, Jiamin Wu, Li Li, Jun Song and Ruixiang Zhou
    Citation: BMC Cancer 2024 24:1158
    Content type: Research Published on:

  26. Absolute lymphocyte count (ALC) is a predictive and prognostic factor for various tumor types, including breast cancer. Palbociclib is a CDK4/6 inhibitor widely used for the treatment of metastatic estrogen re...

    Authors: Takayuki Kobayashi, Meiko Nishimura, Mari Hosonaga, Rika Kizawa, Saori Kawai, Yosuke Aoyama, Yukinori Ozaki, Ippei Fukada, Fumikata Hara, Toshimi Takano and Takayuki Ueno
    Citation: BMC Cancer 2024 24:1156
    Content type: Research Published on:

  27. The response of patients with colorectal cancer to chemotherapy is tightly correlated with their genomic variation. Among these, APC, TP53, KRAS, PIK3CA are the most frequently mutated genes in advanced colore...

    Authors: YiMeng Tang and Yao Fan
    Citation: BMC Cancer 2024 24:1155
    Content type: Research Published on:

  29. Effects of confounders on associations between diet and colorectal cancer (CRC) in observational studies can be minimized in Mendelian randomization (MR) approach. This study aimed to investigate observational...

    Authors: Tung Hoang, Sooyoung Cho, Ji-Yeob Choi, Daehee Kang and Aesun Shin
    Citation: BMC Cancer 2024 24:1153
    Content type: Research Published on:

  30. Tumor-infiltrating lymphocytes (TILs) are significantly implicated in regulating the tumor immune microenvironment (TIME) and immunotherapeutic response. However, little is known about the impact of the reside...

    Authors: Anning Zuo, Jinxiang Lv, Wenlong Jia, Yuhao Ba, Shutong Liu, Yuyuan Zhang, Siyuan Weng, Hui Xu, Long Liu, Libo Wang, Xinwei Han and Zaoqu Liu
    Citation: BMC Cancer 2024 24:1152
    Content type: Research Published on:

  31. We explored the preliminary value of abnormal spindle-like microcephaly- associated (ASPM) protein in aiding precise risk sub-stratification, prediction of metabolic heterogeneity, and prognosis of neuroblasto...

    Authors: Chao Li, Xueyuan Lu, Fengxian Zhang, Shuo Huang, Lin Ding, Hui Wang and Suyun Chen
    Citation: BMC Cancer 2024 24:1151
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2024 24:1221

  32. This study utilizes a meta-analytic approach to investigate the effects of cryoablation and robot-assisted partial nephrectomy on perioperative outcomes, postoperative renal function, and oncological results i...

    Authors: HuiYu Gao, Lin Zhou, JiaBin Zhang, Qiang Wang, ZiYuan Luo, Qian Xu, Ying Tan, Hui Shuai, JunJie Zhou, Xiang Cai, YongBo Zheng, Wang Shan, Xi Duan and Tao Wu
    Citation: BMC Cancer 2024 24:1150
    Content type: Systematic Review Published on:

  33. This multi-center cohort study aimed to investigate whether sex and prediagnosis lifestyle affect the prognosis of gastric cancer.

    Authors: Xiaoyi Luan, Lulu Zhao, Fan Zhang, Wanqing Wang, Fuzhi Jiao, Xiadong Zhou, Penghui Niu, Xue Han, Xiaojie Zhang, Dongbing Zhao, Mingyan He, Quanlin Guan, Yumin Li and Yingtai Chen
    Citation: BMC Cancer 2024 24:1149
    Content type: Research Published on:

  34. Breast cancer (BC) poses significant burdens on women globally. While past research suggests a potential link between bone mineral density (BMD) and BC risk, findings remain inconsistent. Our study aims to elu...

    Authors: Ziyang Cheng, Hui Xu, Xin Wang, Tao Teng, Bin Li, Zhong Cao, Zhichao Li, Jiayi Zhang, Jin Xuan, Fengyi Zhang, Yaxin Chen, Yujie Li and Wenbo Wang
    Citation: BMC Cancer 2024 24:1148
    Content type: Research Published on:

  35. Variations in untranslated regions (UTR) alter regulatory pathways impacting phenotype, disease onset, and course of disease. Protein kinase C Zeta (PRKCZ), a serine-threonine kinase, is implicated in cardiova...

    Authors: Aneela Mustafa, Maria Shabbir, Yasmin Badshah, Khushbukhat Khan, Fizzah Abid, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal and Suhail Razak
    Citation: BMC Cancer 2024 24:1147
    Content type: Research Published on:

  36. The Multidisciplinary Tumor Board (MTB) is a collaborative platform involving specialists in oncology, surgery, radiology, pathology, and radiotherapy, and aims to optimize diagnostics and treatments. Despite ...

    Authors: Rosellina Russo, Tommaso Verdolotti, Alessandro Perna, Luigi Ruscelli, Rosa D’Abronzo, Alberto Romano, Giuseppe Ferrara, Davide Parisi, Amato Infante, Silvia Chiesa, Luca Massimi, Gianpiero Tamburrini, Antonio Ruggiero, Marco Gessi, Matia Martucci and Simona Gaudino
    Citation: BMC Cancer 2024 24:1146
    Content type: Research Published on:

  38. HPV status in a subset of HNSCC is linked with distinct treatment outcomes. Present investigation aims to elucidate the distinct clinicopathological features of HPV-positive and HPV-negative HNSCC and investig...

    Authors: Joni Yadav, Apoorva Chaudhary, Tanya Tripathi, Divya Janjua, Udit Joshi, Nikita Aggarwal, Arun Chhokar, Chetkar Chandra Keshavam, Anna Senrung and Alok Chandra Bharti
    Citation: BMC Cancer 2024 24:1144
    Content type: Research Published on:

  39. F-627 (efbemalenograstim alfa) is a novel long acting granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2) -Fc fragment with a peptide linker. ...

    Authors: Qingyuan Zhang, Zhonghua Wang, Wei Yao, Shufang Wang, Gaochong Zhang, Jianmin Chen, Qingsong Hou, Simon Li, Hongsheng Li, Changsheng Ye, Tao Sun, Hongjian Yang, Zhendong Chen, Zhihong Wang, Xiaoan Liu, Cuizhi Geng…
    Citation: BMC Cancer 2024 24:1143
    Content type: Research Published on:

  40. Colorectal cancer ranks among the most prevalent malignancies globally. Accurate prediction of metachronous liver metastasis is crucial for optimizing postoperative management. Tripartite motif-containing prot...

    Authors: Jiankun Zhu, Shilin Zhi, Jintao Zeng, Shengning Zhou, Yong Ji and Fanghai Han
    Citation: BMC Cancer 2024 24:1142
    Content type: Research Published on:

  41. Curcumin has been reported to have activity for prevention and therapy of CRC, yet its underlying mechanisms remain largely unknown. Recently, emerging evidence suggests that the gut microbiota and its metabol...

    Authors: Wenxin Deng, Xiaojian Xiong, Mingyang Lu, Shibo Huang, Yunfei Luo, Yujie Wang and Ying Ying
    Citation: BMC Cancer 2024 24:1141
    Content type: Research Published on:

  42. In patients with relapsed or refractory neuroblastoma (NB), the limited efficacy of conventional chemotherapies necessitates the exploration of new treatment options. Previous studies have highlighted the anti...

    Authors: Xiaoshan Liu, Xiaomin Peng, Shu Yang, Haijin Liu, Shouhua Zhang, Jinhu Wang, Yuhan Ma, Yu Wu, Zhixuan Wang, Wenjun Weng and Yang Li
    Citation: BMC Cancer 2024 24:1140
    Content type: Research Published on:

  43. MR perfusion is a standard marker to distinguish progression and therapy-associated changes after surgery and radiochemotherapy for glioblastoma. TRAMs (Treatment Response Assessment Maps) were introduced, whi...

    Authors: Eya Khadhraoui, Leon Schmidt, Stefan Klebingat, Roland Schwab, Silvia Hernández-Durán, Georg Gihr, Harald Paukisch, Klaus-Peter Stein, Daniel Behme and Sebastian Johannes Müller
    Citation: BMC Cancer 2024 24:1139
    Content type: Research Published on:

  44. Lung adenocarcinoma (LUAD) significantly contributes to cancer-related mortality worldwide. The heterogeneity of the tumor immune microenvironment in LUAD results in varied prognoses and responses to immunothe...

    Authors: Shengshan Xu, Xiguang Chen, Haoxuan Ying, Jiarong Chen, Min Ye, Zhichao Lin, Xin Zhang, Tao Shen, Zumei Li, Youbin Zheng, Dongxi Zhang, Yongwen Ke, Zhuowen Chen and Zhuming Lu
    Citation: BMC Cancer 2024 24:1138
    Content type: Research Published on:

  45. Exercise is associated with improved survival, physical functioning, treatment tolerability, and quality of life in early-stage breast cancer. These same endpoints matter in metastatic breast cancer (MBC). Pri...

    Authors: Martha A. Cancilla, Donya Nemati, Danielle Halsey, Niraj Shah, Melissa Sherman, Nicholas Kelly, Pengyue Zhang, Nada Kassem, Navin Kaushal, Kelly Shanahan, Lesley Kailani Glenn, Jennifer A. Ligibel and Tarah J. Ballinger
    Citation: BMC Cancer 2024 24:1137
    Content type: Study Protocol Published on:

  46. A variety of solid tumours, including oral squamous cell carcinoma (OSCC), can cause coagulation abnormalities, and this phenomenon is known as tumour-associated hypercoagulation. We aimed to explore the preop...

    Authors: Wan Duan, Zhangxia Wu, Hong Jiang, Guiqing Liao, Yujie Liang and Xiaomei Lao
    Citation: BMC Cancer 2024 24:1136
    Content type: Research Published on:

  48. Cervical cancer, encompassing squamous cell carcinoma and endocervical adenocarcinoma (CESC), presents a considerable risk to the well-being of women. Recent studies have reported that squalene epoxidase (SQLE...

    Authors: Yue-Chen Zhao, Yun-Feng Li, Ling Qiu, Shun-Zi Jin, Yan-Nan Shen, Chao-He Zhang, Jie Cui and Tie-Jun Wang
    Citation: BMC Cancer 2024 24:1133
    Content type: Research Published on:

  50. Gastric cancer is one of the most malignant digestive tract tumors worldwide and its progression is associated with gene expression and metabolic alteration. We revealed that the gastric cancer patients with l...

    Authors: Hongjie He, Kexian Dong, Mingming Chen, Yuanyuan Wang, Yawen Li, Dong Wang, Mansha Jia, Xiangning Meng, Wenjing Sun, Songbin Fu and Jingcui Yu
    Citation: BMC Cancer 2024 24:1130
    Content type: Research Published on:

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