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  1. Cancer-associated fibroblasts (CAFs) play an important role in the tumor microenvironment. Despite the well-known in vitro antitumoral effect of vitamin D3 (VD3), its impact on breast CAFs is almost unknown. In t...

    Authors: Natalia Łabędź, Artur Anisiewicz, Martyna Stachowicz-Suhs, Joanna Banach, Dagmara Kłopotowska, Adam Maciejczyk, Patrycja Gazińska, Aleksandra Piotrowska, Piotr Dzięgiel, Rafał Matkowski and Joanna Wietrzyk
    Citation: BMC Cancer 2024 24:209
  2. Despite the known association between healthy lifestyles and reduced risk of breast cancer, it remains unclear whether systemic inflammation, as a consequence of unhealthy lifestyles, may mediate the association.

    Authors: Yanyu Zhang, Mengjie Song, Zixuan Yang, Xiaoxi Huang, Yuxiang Lin and Haomin Yang
    Citation: BMC Cancer 2024 24:208
  3. Ovarian cancer (OC) is a complex disease with significant tumor heterogeneity with the worst prognosis and highest mortality among all gynecological cancers. Glycosylation is a specific post-translational modi...

    Authors: Yue You and Qing Yang
    Citation: BMC Cancer 2024 24:207
  4. This study is designed to explore the potential impact of individual and environmental residential factors as risk determinants for bone and soft tissue cancers, with a particular focus on the Indonesian conte...

    Authors: Yusuf Alam Romadhon, Yuni Prastyo Kurniati, Jumadi Jumadi, Ali Asghar Alesheikh and Aynaz Lotfata
    Citation: BMC Cancer 2024 24:206
  5. Colorectal cancer (CRC) is an aggressive tumor of the gastrointestinal tract, which is a major public health concern worldwide. Despite numerous studies, the precise mechanism of metastasis behind its progress...

    Authors: Yong Tang, Yi Liu, Xiaobo Wang, Haiyang Guo, Lin Chen, Guangbing Hu, Yutong Cui, Shiqi Liang, Ji Zuo, Zichen Luo, Xinrui Chen and Xianfei Wang
    Citation: BMC Cancer 2024 24:204
  6. Chemotherapy is included in treatment regimens for many solid cancers, but when administered as a single agent it is rarely curative. The addition of immune checkpoint therapy to standard chemotherapy regimens...

    Authors: Caitlin M. Tilsed, M. Lizeth Orozco Morales, Rachael M. Zemek, Brianna A. Gordon, Matthew J. Piggott, Anna K. Nowak, Scott A. Fisher, Richard A. Lake and W. Joost Lesterhuis
    Citation: BMC Cancer 2024 24:203
  7. A combination of immune checkpoint inhibitors (ICIs) and chemotherapy has demonstrated excellent clinical efficacy and safety in treating a variety of cancers, including urothelial carcinoma (UC). However, its...

    Authors: Jingwen Zhang, Meng Yang, Dongqun Wei, Deru Zhang, Zeyu Chen and Haitao Zhu
    Citation: BMC Cancer 2024 24:202
  8. For patients with liver-confined metastatic colorectal cancer (mCRC), local therapy of isolated metastases has been associated with long-term progression-free and overall survival (OS). However, for patients w...

    Authors: Kathryn E. Hitchcock, Eric D. Miller, Qian Shi, Jesse G. Dixon, Sepideh Gholami, Sarah B. White, Christina Wu, Christopher C. Goulet, Manju George, Kyung-Wook Jee, Chadwick L. Wright, Rona Yaeger, Ardaman Shergill, Theodore S. Hong, Thomas J. George, Eileen M. O’Reilly…
    Citation: BMC Cancer 2024 24:201
  9. EGFR inhibitor and immunotherapy have been approved for adjuvant treatment in resectable non-small cell lung cancer (NSCLC). Limited reports of molecular and clinical characteristics as prognostic factors in N...

    Authors: T. Thamrongjirapat, D. Muntham, P. Incharoen, N. Trachu, P. Sae-Lim, N. Sarachai, K. Khiewngam, N. Monnamo, N. Kantathut, M. Ngodngamthaweesuk, T. Ativitavas, P. Chansriwong, C. Nitiwarangkul, R. Ruangkanchanasetr, A. Kositwattanarerk, E. Sirachainan…
    Citation: BMC Cancer 2024 24:200
  10. Glioblastoma (GBM) is an aggressive brain tumor that exhibits resistance to current treatment, making the identification of novel therapeutic targets essential. In this context, cellular prion protein (PrPC) stan...

    Authors: Jacqueline Marcia Boccacino, Rafael dos Santos Peixoto, Camila Felix de Lima Fernandes, Giovanni Cangiano, Paula Rodrigues Sola, Bárbara Paranhos Coelho, Mariana Brandão Prado, Maria Isabel Melo-Escobar, Breno Pereira de Sousa, Shamini Ayyadhury, Gary D. Bader, Sueli Mieko Oba Shinjo, Suely Kazue Nagahashi Marie, Edroaldo Lummertz da Rocha and Marilene Hohmuth Lopes
    Citation: BMC Cancer 2024 24:199
  11. Osteosarcoma (OS) is one of the most common aggressive bone malignancy tumors in adolescents. With the application of new chemotherapy regimens, finding new and effective anti-OS drugs to coordinate program im...

    Authors: Feifan Zhang, Yang Hao, Ning Yang, Man Liu, Yage Luo, Ying Zhang, Jian Zhou, Hongjian Liu and Jitian Li
    Citation: BMC Cancer 2024 24:198
  12. The superior efficacy of concurrent thoracic radiotherapy (TRT) and epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) has been proven in locally advanced and advanced non-small cell lung ...

    Authors: Hanjing Yin, Wenxiao Jia, Jinming Yu and Hui Zhu
    Citation: BMC Cancer 2024 24:197
  13. In the management of urothelial carcinoma, patient selection for immunotherapy, particularly with immune checkpoint inhibitors such as PD-1 (programmed cell death protein 1), is important for treatment effica...

    Authors: Meng Yang, Jingwen Zhang, Dongqun Wei, Tianyi Yu, Zeyu Chen, Xin Liu and Haitao Zhu
    Citation: BMC Cancer 2024 24:196
  14. Studies have shown that the absolute lymphocyte count (ALC) and the neutrophil-to-lymphocyte ratio (NLR) are related to the outcomes in patients with breast cancer receiving specific chemotherapies. However, t...

    Authors: Meng-Xia Su, Hsiang-Wen Lin, Hanh T. H. Nguyen, Tien-Chao Lin, Chih-Jung Chen, Hwei-Chung Wang, Chen-Teng Wu, Yao-Chung Wu, Geng-Yan He, Liang-Chih Liu and Chih-Hao Huang
    Citation: BMC Cancer 2024 24:195
  15. Hepatocellular carcinoma (HCC) is the most common type of malignant liver tumor with poor prognosis. In this study, we investigated the expression of transforming growth factor beta regulator 4 (TBRG4) in HCC ...

    Authors: Shanchun Tao, Di Cui, Huimin Cheng, Xiaofei Liu, Zhaobin Jiang, Hongwei Chen and Yong Gao
    Citation: BMC Cancer 2024 24:194
  16. Prognosis prediction for pancreatic cancer has always been difficult in clinical practice because of its high heterogeneity and mortality. The aim of the study was to assess the value of prognostic immune-infl...

    Authors: Jie Yang, Hongkun Zhou, Huangbao Li, Fengqing Zhao and Kun Tong
    Citation: BMC Cancer 2024 24:193
  17. Recent advances in the management of pancreatic neuroendocrine tumors (pNETs) highlight the potential benefits of temozolomide, an alkylating agent, for these patients. In this meta-analysis, we aimed to asses...

    Authors: Erfan Taherifard, Muhammad Bakhtiar, Mahnoor Mahnoor, Rabeea Ahmed, Ludimila Cavalcante, Janie Zhang and Anwaar Saeed
    Citation: BMC Cancer 2024 24:192
  18. Cancer is a significant public health concern and the second leading cause of death. This study aims to visualize spatial patterns of top common cancer types and identify high-risk and low-risk counties for th...

    Authors: Sharareh Faramarzi, Behzad Kiani, Shahla Faramarzi and Neda Firouraghi
    Citation: BMC Cancer 2024 24:191
  19. Histiocytoses are rare disorders manifested by increased proliferation of pathogenic myeloid cells sharing histological features with macrophages or dendritic cells and accumulating in various organs, i.a., bo...

    Authors: Agnieszka Śmieszek, Klaudia Marcinkowska, Zofia Małas, Mateusz Sikora, Martyna Kępska, Beata A. Nowakowska, Marta Deperas, Marta Smyk, Carlos Rodriguez-Galindo and Anna Raciborska
    Citation: BMC Cancer 2024 24:105
  20. The purpose of this propensity score matching (PSM) analysis was to compare the effects of preoperative transcatheter arterial chemoembolization (TACE) and non-TACE on the long-term survival of patients who un...

    Authors: Run Hu, Jie Xu, Hongxiang Wang, Jiaguo Wang, Kai Lei, Xiaoping Zhao, Huizhi Zhang, Ke You and Zuojin Liu
    Citation: BMC Cancer 2024 24:190
  21. The partitioned survival model (PSM) and the state transition model (STM) are widely used in cost-effectiveness analyses of anticancer drugs. Using different modeling approaches with or without consideration o...

    Authors: Yoon-Bo Shim, Byeong-Chan Oh, Eui-Kyung Lee and Mi-Hai Park
    Citation: BMC Cancer 2024 24:189
  22. There is limited evidence of comparative results among different treatments regarding impacts of Health-Related Quality of Life (HRQoL) for patients with metastatic colorectal cancer (mCRC). We aimed to compar...

    Authors: Yunlin Jiang, Mingye Zhao, Wenxi Tang and Xueping Zheng
    Citation: BMC Cancer 2024 24:188
  23. To compare the efficacy, safety and effects on quality of life of different ALK-inhibitors for global and Asian patients with advanced ALK-positive non-small-cell lung cancer (NSCLC).

    Authors: Mingye Zhao, Taihang Shao, Hanqiao Shao, Caicun Zhou and Wenxi Tang
    Citation: BMC Cancer 2024 24:186
  24. Predicting tumor responses to neoadjuvant chemotherapy (NAC) is critical for evaluating prognosis and designing treatment strategies for patients with breast cancer; however, there are no reliable biomarkers t...

    Authors: Min Woo Kim, Hyojung Lee, Suji Lee, Sol Moon, Young Kim, Joon Ye Kim, Seung Il Kim and Jee Ye Kim
    Citation: BMC Cancer 2024 24:185
  25. Sinonasal mucosal melanoma (SNMM) is a relatively rare malignant tumour with a poor prognosis. This study was designed to identify prognostic factors and establish a nomogram model to predict the overall survi...

    Authors: Zhenzhen Zhu, Weiqing Wang, Yang Zha, Xiaowei Wang, Surita Aodeng, Lei Wang, Yuzhuo Liu and Wei Lv
    Citation: BMC Cancer 2024 24:184
  26. Lung cancer (LC) has poor survival outcomes mainly due to diagnosis at late stages. This study explored the anticipated time to seek medical advice for possible LC symptoms and barriers to early presentation i...

    Authors: Mohamedraed Elshami, Nawras Sawafta, Ahmad Mansour, Mohammed Alser, Ibrahim Al-Slaibi, Hanan Abukmail, Hanan Shurrab, Shahd Qassem, Faten Darwish Usrof, Malik Alruzayqat, Wafa Aqel, Roba Nairoukh, Rahaf Kittaneh, Yousef Mahmoud Nimer Habes, Obaida Ghanim, Wesam Almajd Aabed…
    Citation: BMC Cancer 2024 24:183
  27. Breast cancer (BC) is the second-leading factor of mortality for women globally and is brought on by a variety of genetic and environmental causes. The conventional treatments for this disease have limitations...

    Authors: Ying Jiang, Jiayu Liu, Lingyan Chen, Zhiwen Qian and Yan Zhang
    Citation: BMC Cancer 2024 24:182
  28. In this meta-analysis, we conducted a comparative analysis of the safety and efficacy of hypofractionated and conventional fractionated radiotherapy in individuals who had undergone surgery for breast cancer.

    Authors: Yongkai Lu, Beina Hui, Di Yang, Yi Li, Binglin Li, Luping Zhou, Lei Xu, Fengwen Tang, Wei Wang, Ruijuan Chen and Dongli Zhao
    Citation: BMC Cancer 2024 24:181
  29. Men with breast cancer experience unique physical and emotional challenges. However, a thorough understanding of these experiences including the psychosocial effects and supportive care needs have received les...

    Authors: Mary Abboah-Offei, Jonathan Bayuo, Yakubu Salifu, Oladayo Afolabi and Theophilus N. Akudjedu
    Citation: BMC Cancer 2024 24:179
  30. Neoadjuvant chemoradiotherapy (nCRT) and surgery have been recommended as the standard treatments for locally advanced esophageal squamous cell carcinoma (ESCC). In addition, nodal metastases decreased in freq...

    Authors: Run-Da Lu, Zheng-Dao Wei, Yi-Xin Liu, Dong Tian, Han-Lu Zhang, Qi-Xin Shang, Wei-Peng Hu, Lin Yang, Yu-Shang Yang and Long-Qi Chen
    Citation: BMC Cancer 2024 24:177
  31. This study aimed to evaluate the efficacy and side effects of first-line afatinib treatment in a real-world setting in Vietnam.

    Authors: Cam Phuong Pham, Thi Thai Hoa Nguyen, Anh Tu Do, Tuan Khoi Nguyen, Thi Anh Thu Hoang, Tuan Anh Le, Dinh Thy Hao Vuong, Dac Nhan Tam Nguyen, Van Khiem Dang, Thi Oanh Nguyen, Van Luan Pham, Minh Hai Nguyen, Thi Huyen Trang Vo, Hung Kien Do, Ha Thanh Vu, Thi Thuy Hang Nguyen…
    Citation: BMC Cancer 2024 24:176
  32. Targeted drugs are the main methods of RCC treatment. However, drug resistance is common in RCC patients, in-depth study of the drug-resistant mechanism is essential.

    Authors: Fangzhen Cai, Jianwei Li, Yanmei Zhang, Sihuai Huang, Wenbin Liu, Weifeng Zhuo and Chengzhi Qiu
    Citation: BMC Cancer 2024 24:175
  33. High levels of physical activity are associated with reduced risk of the blood cancer multiple myeloma (MM). MM is preceded by the asymptomatic stages of monoclonal gammopathy of undetermined significance (MGU...

    Authors: A Emery, S Moore, J Crowe, J Murray, O Peacock, D Thompson, F Betts, S Rapps, L Ross, D Rothschild-Rodriguez, A Arana Echarri, R Davies, R Lewis, DX Augustine, A Whiteway, Z Afzal…
    Citation: BMC Cancer 2024 24:174
  34. Copy-number alterations (CNAs) are a hallmark of cancer and can regulate cancer cell states via altered gene expression values. Herein, we have developed a copy-number impact (CNI) analysis method that quantif...

    Authors: Sanaz Jamalzadeh, Jun Dai, Kari Lavikka, Yilin Li, Jing Jiang, Kaisa Huhtinen, Anni Virtanen, Jaana Oikkonen, Sakari Hietanen, Johanna Hynninen, Anna Vähärautio, Antti Häkkinen and Sampsa Hautaniemi
    Citation: BMC Cancer 2024 24:173
  35. Epithelioid sarcoma is a rare soft tissue sarcoma characterized by SMARCB1/INI1 deficiency. Much attention has been paid to the selective EZH2 inhibitor tazemetostat, where other systemic treatments are genera...

    Authors: Lu Xie, Xin Sun, Jie Xu, Xin Liang, Kuisheng Liu, Kunkun Sun, Rongli Yang, Xiaodong Tang and Wei Guo
    Citation: BMC Cancer 2024 24:172
  36. Radiotherapy delivery regimens can vary between a single fraction (SF) and multiple fractions (MF) given daily for up to several weeks depending on the location of the cancer or metastases. With limited eviden...

    Authors: Robert Olson, Hadassah Abraham, Curtis Leclerc, Alexander Benny, Sarah Baker, Quinn Matthews, Nick Chng, Alanah Bergman, Benjamin Mou, Emma M. Dunne, Devin Schellenberg, Will Jiang, Elisa Chan, Siavash Atrchian, Shilo Lefresne, Hannah Carolan…
    Citation: BMC Cancer 2024 24:171
  37. The prognosis of SCLC is poor and difficult to predict. The aim of this study was to explore whether a model based on radiomics and clinical features could predict the prognosis of patients with limited-stage ...

    Authors: Jiehan Wu, Yuntao Zhou, Chang Xu, Chengwen Yang, Bingxin Liu, Lujun Zhao, Jiawei Song, Wei Wang, Yining Yang and Ningbo Liu
    Citation: BMC Cancer 2024 24:170
  38. This study aimed to compare the efficacy of focused ultrasound (FUS) and the loop electrosurgical excision procedure (LEEP) for the treatment of cervical high-grade squamous intraepithelial lesions (HSILs) amo...

    Authors: Linlin Xiao, Xu Dong, Jiangchuan Sun, Xuerui Zhang, Qing Feng and Shufang Chang
    Citation: BMC Cancer 2024 24:169
  39. Oxaliplatin-induced peripheral neuropathy (OIPN) in general and painful OIPN in particular is a debilitating late effect that severely affects cancer survivors’ quality of life and causes premature cessation o...

    Authors: Nina Lykkegaard Gehr, Páll Karlsson, Signe Timm, Signe Christensen, Christian Andreas Hvid, Jana Peric, Torben Frøstrup Hansen, Lotte Lauritzen, Nanna Brix Finnerup and Lise Ventzel
    Citation: BMC Cancer 2024 24:168
  40. Breast carcinoma (BC) ranks as a predominant malignancy and constitutes the second principal cause of mortality among women globally. Epirubicin stands as the drug of choice for BC therapeutics. Nevertheless, ...

    Authors: Yunwei Zhang, Yunping Guan, Xinyu Zheng and Chenyang Li
    Citation: BMC Cancer 2024 24:167
  41. Osteosarcoma (OS) is a highly malignant tumor, and its dysregulated lipid metabolism is associated with tumorigenesis and unfavorable prognosis. Interestingly, long noncoding RNAs (lncRNAs) have emerged as piv...

    Authors: Feng Cai, Luhua Liu, Yuan Bo, Wenjing Yan, Xuchang Tao, Yuanxiang Peng, Zhiping Zhang, Qi Liao and Yangyan Yi
    Citation: BMC Cancer 2024 24:166
  42. To improve the prognosis of patients with metastatic colorectal cancer (mCRC), investigating predictive biomarkers of their prognosis and chemotherapeutic responsiveness is necessary. This study aimed to analy...

    Authors: Kei Furuya, Masao Nakajima, Ryouichi Tsunedomi, Yuki Nakagami, Ming Xu, Hiroto Matsui, Yukio Tokumitsu, Yoshitaro Shindo, Yusaku Watanabe, Shinobu Tomochika, Noriko Maeda, Michihisa Iida, Nobuaki Suzuki, Shigeru Takeda, Shoichi Hazama, Tatsuya Ioka…
    Citation: BMC Cancer 2024 24:165
  43. For high-risk stageIImismatch repair deficient (dMMR) colon cancers, the benefit of adjuvant chemotherapy remains debatable. The principal aim of this study was to evaluate the prognostic value of high-risk fa...

    Authors: Leen Liao, Jinghua Tang, Zhigang Hong, Wu Jiang, Yuan Li, Lingheng Kong, Kai Han, Zhenlin Hou, Chenzhi Zhang, Chi Zhou, Linjie Zhang, Qiaoqi Sui, Binyi Xiao, Weijian Mei, Jiehai Yu, Wanjun Yang…
    Citation: BMC Cancer 2024 24:164
  44. Despite advancements in managing metastatic clear cell renal carcinoma (mccRCC) through antiangiogenic tyrosine kinase inhibitors and immunotherapy, there remains a demand for novel treatments for patients exp...

    Authors: David Kryza, Armelle Vinceneux, Anne-Sophie Bidaux, Gwenaelle Garin, Delphine Tatu, Claire Cropet, Jean-Noël Badel, David Perol and Anne-Laure Giraudet
    Citation: BMC Cancer 2024 24:163
  45. Colorectal cancer (CRC) is a common malignancy worldwide. MicroRNAs (miRNAs) are important epigenetic alterations that notably impact various physiological and pathological processes by acting as negative regu...

    Authors: Bayan Mehrjoei, Lida Haghnazari, Homayoon Bashiri and Nayebali Rezvani
    Citation: BMC Cancer 2024 24:162
  46. In 2020, the highest incidence and mortality from cervical cancer (CC) were detected in low and middle-income countries. CC remains a health problem for women living in them. In Mexico, CC ranks second in canc...

    Authors: Lucely Cetina-Pérez, Julissa Luvián-Morales, Merari Delgadillo-González, Denisse Castro-Eguiluz, Tatiana Galicia-Carmona, Kely Rely, Rita Vaca González, Gabriela Lugo-Martínez, Nadia García-Barrientos and Antonio Nateras
    Citation: BMC Cancer 2024 24:161

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