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  2. Our previous studies have indicated that mRNA and protein levels of PPIH are significantly upregulated in Hepatocellular Carcinoma (LIHC) and could act as predictive biomarkers for patients with LIHC. Nonetheless...

    Authors: Jun Ye, Jianchao Ying, Haixia Chen, Zhiping Wu, Chaolin Huang, Chuan Zhang, Zhitao Chen and Haini Chen
    Citation: BMC Cancer 2024 24:681
    Content type: Research Published on:

  3. To evaluate the feasibility, safety and efficacy of concurrent simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) combined with nimotuzumab in the treatment of locally advanced esophagea...

    Authors: Lan Wang, Lihong Liu, Yu Cao, Xiaoxi Chen, Shutang Liu, Xiaoning Li, Jing Han, Qi Wang and Chun Han
    Citation: BMC Cancer 2024 24:679
    Content type: Research Published on:

  4. Despite several preventative and control measures Ethiopia continues to see an increase in cervical cancer. Comprehensive evidence is very important to suggest ministry of health. Therefore, the aim of this st...

    Authors: Yeshiwas Ayale Ferede, Worku Chekol Tassew and Agerie Mengistie Zeleke
    Citation: BMC Cancer 2024 24:678
    Content type: Systematic Review Published on:

  5. Mortality benefit of transfusion with leucoreduced whole blood has not been demonstrated in the sub-Saharan Africa (SSA). We compared mortality in patients with cancer transfused with leucoreduced and non-leuc...

    Authors: Clement D. Okello, Jackson Orem, Martin Nabwana, Noah Kiwanuka, Andrew W. Shih, Nancy Heddle and Harriet Mayanja-Kizza
    Citation: BMC Cancer 2024 24:677
    Content type: Research Published on:

  6. Circulating total insulin-like growth factor-I (IGF-I) is an established risk factor for prostate cancer. However, only a small proportion of circulating IGF-I is free or readily dissociable from IGF-binding p...

    Authors: Tuck Seng Cheng, Urwah Noor, Eleanor Watts, Michael Pollak, Ye Wang, James McKay, Joshua Atkins, Giovanna Masala, Maria-Jose Sánchez, Antonio Agudo, Jesús Castilla, Dagfinn Aune, Sandra M. Colorado-Yohar, Luca Manfredi, Marc J. Gunter, Valeria Pala…
    Citation: BMC Cancer 2024 24:676
    Content type: Research Published on:

  7. Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine tumour of the skin with poor prognosis and rising global incidence. A recently published article in BMC Cancer, titled “Merkel cell carcinoma...

    Authors: James Leigh and Kurt Gebauer
    Citation: BMC Cancer 2024 24:675
    Content type: Matters Arising Published on:

  8. Colorectal cancer is the leading cause of cancer death worldwide. The first and second lines of treatment for metastatic colorectal cancer (mCRC) include chemotherapy based on 5-fluorouracil. However, treatmen...

    Authors: Francisco Cezar Aquino de Moraes, Felipe Dircêu Dantas Leite Pessôa, Caio Henrique Duarte de Castro Ribeiro, Marianne Rodrigues Fernandes, Rommel Mario Rodríguez Burbano and Ney Pereira Carneiro dos Santos
    Citation: BMC Cancer 2024 24:674
    Content type: Research Published on:

  9. Hepatocellular carcinoma (HCC) genomic research has discovered actionable genetic changes that might guide treatment decisions and clinical trials. Nonetheless, due to a lack of large-scale multicenter clinica...

    Authors: Mengqi Song, Haoyue Cheng, Hao Zou, Kai Ma, Lianfang Lu, Qian Wei, Zejiang Xu, Zirui Tang, Yuanzheng Zhang, Yinan Wang and Chuandong Sun
    Citation: BMC Cancer 2024 24:673
    Content type: Research Published on:

  10. Patients with primary multifocal hepatocellular carcinoma (HCC) have a poor prognosis and often experience a high rate of treatment failure. Multifocal HCC is mainly caused by intrahepatic metastasis (IM), and...

    Authors: Weilong Zou, Zhanjie Fang, Yu Feng, Shangjin Gong, Ziqiang Li, Meng Li, Yong Sun, Xiuyan Ruan, Xiangdong Fang, Hongzhu Qu and Haiyang Li
    Citation: BMC Cancer 2024 24:672
    Content type: Research Published on:

  11. The role of novel circular RNAs (circRNAs) in colorectal cancer (CRC) remains to be determined. This study aimed to identify a novel circRNA involved in CRC pathogenesis, assess its diagnostic value, and const...

    Authors: Ke-zhi Li, Xiao-min Liao, Si-qi Li, Hao-tang Wei, Zhi-jian Liang, Liu-xin Ge, Su-fang Zhou and Bang-li Hu
    Citation: BMC Cancer 2024 24:671
    Content type: Research Published on:

  12. An accurate and non-invasive approach is urgently needed to distinguish tuberculosis granulomas from lung adenocarcinomas. This study aimed to develop and validate a nomogram based on contrast enhanced-compute...

    Authors: Liping Yang, Zhiyun Jiang, Jinlong Tong, Nan Li, Qing Dong and Kezheng Wang
    Citation: BMC Cancer 2024 24:670
    Content type: Research Published on:

  13. Cancer has become a major health concern due to the increasing morbidity and mortality rates, and its negative social, economic consequences and the heavy financial burden incurred by cancer patients. About 40...

    Authors: Mohamed Khalis, Imad Elbadisy, Oumnia Bouaddi, Amy Luo, Amina Bendriouich, Badr Addahri, Hafida Charaka, Mohamed Chahboune, Jérôme Foucaud, Abdallah Badou, Lahcen Belyamani and Inge Huybrechts
    Citation: BMC Cancer 2024 24:669
    Content type: Research Published on:

  14. Gastrointestinal cancers represent one of the most prevalent diseases worldwide. Strikingly, the incidence of Early Onset Gastrointestinal Cancer (EOGIC) has been rising during the last decades and changes in ...

    Authors: R. Vera, N. Castro, I. Labiano, A. Lecumberri, A. E. Huerta, H. Arasanz, I. Caseda, F. Ruiz-Pace, C. Viaplana, V. Arrazubi, I. Hernandez-Garcia, E. Mata, D. Gomez, S. Laguna, J. Suarez, I. Fernandez-De-los-Reyes…
    Citation: BMC Cancer 2024 24:668
    Content type: Study Protocol Published on:

  15. The causal impact of lipid-lowering drugs on ovarian cancer (OC) and cervical cancer (CC) has received considerable attention, but its causal relationship is still a subject of debate. Hence, the objective of ...

    Authors: Jinshuai Li, Zixian Yang, Tao Wang, Mengqi Li, Xiangjian Wu, Xiaoyan Fu, Chunfeng Yang, Yangpu Li, Ximing Wang, Zhiming Lan, Minfang Li and Sheng Chen
    Citation: BMC Cancer 2024 24:667
    Content type: Research Published on:

  16. Currently, there is no consensus on the treatment of recurrent hepatocellular carcinoma (HCC) after hepatectomy. It is necessary to assess the efficacy and safety of radiofrequency ablation (RFA) combined with...

    Authors: Fei Cao, Jiaping Zheng and Weiyuan Hao
    Citation: BMC Cancer 2024 24:666
    Content type: Research Published on:

  18. Recent studies have shown that blue light-emitting diode (LED) light has anti-tumor effects, suggesting the possibility of using visible light in cancer therapy. However, the effects of blue light irradiation ...

    Authors: Toshiaki Yoshimoto, Masaaki Nishi, Shohei Okikawa, Kozo Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Yuma Wada, Takayuki Noma and Mitsuo Shimada
    Citation: BMC Cancer 2024 24:664
    Content type: Research Published on:

  19. Death anxiety is thought to cause a range of mental disorders among cancer patients, which may affect their mental health and even quality of life. This study sought to investigate experiential avoidance, mean...

    Authors: Yixia Yan, Yongyi Chen, Meijun Ou, Youwen Gong, Renting Yang, Xiangyu Liu, Wanting Xia, Furong Chen, Hongling Zheng and Xianghua Xu
    Citation: BMC Cancer 2024 24:663
    Content type: Research Published on:

  20. Despite increased use of immune checkpoint inhibitors (ICIs) in patients with advanced melanoma, little is known about patient experiences during this treatment. This study aimed to gain an in-depth understand...

    Authors: Nadia C.W. Kamminga, Astrid A.M. van der Veldt, Marlies Wakkee, Fauve R. van den Berge, Lianne A.A. van der Beek, Margot C.W. Joosen, Arjen Joosse, Karlijn de Joode, Tamar E.C. Nijsten and Marjolein Lugtenberg
    Citation: BMC Cancer 2024 24:662
    Content type: Research Published on:

  21. In the era of targeted therapies, the influence of aging on cancer management varies from one patient to another. Assessing individual frailty using geriatric tools has its limitations, and is not appropriate ...

    Authors: Mélanie Casile, Gilles Albrand, Benjamin Lebecque, Joévin Besombes, Céline Bourgne, Bruno Pereira, Sandrine Saugues, Caroline Jamot, Eric Hermet and Marc G. Berger
    Citation: BMC Cancer 2024 24:661
    Content type: Study Protocol Published on:

  22. Breast and cervical cancer are the two leading cancers in terms of incidence and mortality. Previous studies reported different interleukins, including interleukin-17A (IL-17A) to be responsible for the developme...

    Authors: Md. Abdul Aziz, Subrina Chowdhury, Sarah Jafrin, Md Abdul Barek, Mohammad Sarowar Uddin, Md. Shalahuddin Millat and Mohammad Safiqul Islam
    Citation: BMC Cancer 2024 24:660
    Content type: Research Published on:

  23. To investigate the diagnostic efficacy of high-frame-rate contrast-enhanced ultrasound (H-CEUS) in differentiating between clear cell renal cell carcinoma (CCRCC) and angiomyolipoma (AML).

    Authors: JingLing Wang, JiaYu Shi, Long Gao, WeiHong Hu, Miao Chen and WeiPing Zhang
    Citation: BMC Cancer 2024 24:659
    Content type: Research Published on:

  24. Adherence to chemotherapy treatment is recognized as a crucial health concern, especially in managing cancer patients. Chemotherapy presents challenges for patients, as it can lead to potential side effects th...

    Authors: Amineh Rashidi, Susma Thapa, Wasana Sandamali Kahawaththa Palliya Guruge and Shubhpreet Kaur
    Citation: BMC Cancer 2024 24:658
    Content type: Systematic Review Published on:

  25. The aim is to establish and verify reference intervals (RIs) for serum tumor markers for an apparently healthy elderly population in Southwestern China using an indirect method.

    Authors: Qiang Miao, Shuting Lei, Fengyu Chen, Qian Niu, Han Luo and Bei Cai
    Citation: BMC Cancer 2024 24:657
    Content type: Research Published on:

  27. This study aims to compare treatment outcomes between neoadjuvant chemotherapy (NACT) followed by surgery and concurrent chemoradiotherapy (CCRT) in patients with stage IIB cervical squamous cell carcinoma (CS...

    Authors: Xin-Bin Pan, Yan Lu, You-Sheng Wei and De-Sheng Yao
    Citation: BMC Cancer 2024 24:655
    Content type: Research Published on:

  28. Immune checkpoint inhibitors (ICIs) have demonstrated superior clinical efficacy in prolonging overall survival (OS) as the second-line treatment for advanced or metastatic esophageal squamous cell carcinoma (...

    Authors: Xiuli Yang, Xiaochun Zheng, Sang Hu, Jinlong Huang, Miaomiao Zhang, Ping Huang and Jiangfeng Wang
    Citation: BMC Cancer 2024 24:654
    Content type: Research Published on:

  29. Pancreatic cancer, a highly fatal malignancy, has shown a global rise in the incidence and mortality rates. However, these rates vary significantly across different regions worldwide. This study aims to assess...

    Authors: Nasr Eldin Elwali, Saad Mohammed AlShareef, Ammar H. Khamis and Moawia M. A. Elhassan
    Citation: BMC Cancer 2024 24:653
    Content type: Research Published on:

  30. Pancreatic ductal adenocarcinoma (PDAC) ranks among the deadliest types of cancer, and it will be meaningful to search for new biomarkers with prognostic value to help clinicians tailor therapeutic strategies.

    Authors: Xiwen Chen, Linying Chen, Jikui Miao, Xingxin Huang, Xiahui Han, Liqin Zheng, Shuoyu Xu, Jianxin Chen and Lianhuang Li
    Citation: BMC Cancer 2024 24:652
    Content type: Research Published on:

  32. This study aimed to explore the effect of CD276 expression on the sunitinib sensitivity of clear cell renal cell carcinoma (ccRCC) cell and animal models and the potential mechanisms involved.

    Authors: Zhi-yu Zhang, Jian-hao Xu, Jiang-lei Zhang, Yu-xin Lin and Jun Ou-Yang
    Citation: BMC Cancer 2024 24:650
    Content type: Research Published on:

  33. Neoadjuvant immune checkpoint blockade (ICB) combined with chemoradiotherapy offers high pathologic complete response (pCR) rate for patients with locally advanced esophageal squamous cell carcinomas (ESCC). B...

    Authors: Dan-Dan Zheng, Yu-Ying Li, Xiao-Yi Yuan, Jiang-Li Lu, Mei-Fang Zhang, Jia Fu and Chris Zhiyi Zhang
    Citation: BMC Cancer 2024 24:649
    Content type: Research Published on:

  34. This study aimed to assess the long-term effect of level IIb clinical target volume (CTV) optimisation on survival, xerostomia, and dysphagia in patients with nasopharyngeal carcinoma (NPC).

    Authors: Jiawei Zhou, Li Wang, Ting Qiu, Han Gao, Lijun Wang, Shengfu Huang, Xia He and Lirong Wu
    Citation: BMC Cancer 2024 24:648
    Content type: Research Published on:

  35. Patient satisfaction is an important indicator of the quality of healthcare. Pain is one of the most common symptoms among cancer patients that needs optimal treatment; rather, it compromises the quality of li...

    Authors: Molla Amsalu, Henos Enyew Ashagrie, Amare Belete Getahun and Yophtahe Woldegerima Berhe
    Citation: BMC Cancer 2024 24:647
    Content type: Research Published on:

  36. Radiotherapy interruption (RTI) prolongs the overall total treatment time and leads to local control loss in many cancers, but it is unclear in esophageal cancer. We aimed to evaluate the influence of RTI on t...

    Authors: Yanhong Mou, Peng Liang, Xun Cheng, Xin He, Jun Zhang, Liangzhong Liu and Qiang Liu
    Citation: BMC Cancer 2024 24:646
    Content type: Research Published on:

  37. Cerebellar degeneration-related (CDR) proteins are associated with paraneoplastic cerebellar degeneration (PCD) – a rare, neurodegenerative disease caused by tumour-induced autoimmunity against neural antigens...

    Authors: Eirik Tveit Solheim, Yola Gerking, Torbjørn Kråkenes, Ida Herdlevær, Even Birkeland, Cecilie Totland, Fiona Dick and Christian Alexander Vedeler
    Citation: BMC Cancer 2024 24:645
    Content type: Research Published on:

  38. Understanding the metabolic changes in colorectal cancer (CRC) and exploring potential diagnostic biomarkers is crucial for elucidating its pathogenesis and reducing mortality. Cancer cells are typically deriv...

    Authors: Xuancheng Wang, Xuan Guan, Ying Tong, Yunxiao Liang, Zongsheng Huang, Mingsen Wen, Jichu Luo, Hongwei Chen, Shanyi Yang, Zhiyong She, Zhijuan Wei, Yun Zhou, Yali Qi, Pingchuan Zhu, Yanying Nong and Qisong Zhang
    Citation: BMC Cancer 2024 24:644
    Content type: Research Published on:

  39. The proposed trial is to examine the feasibility of prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT)-guided cytoreduction plus apalutamide and androgen depriv...

    Authors: Beihe Wang, Jian Pan, Tingwei Zhang, Xudong Ni, Yu Wei, Xiaomeng Li, Bangwei Fang, Xiaoxin Hu, Hualei Gan, Junlong Wu, Hongkai Wang, Dingwei Ye and Yao Zhu
    Citation: BMC Cancer 2024 24:643
    Content type: Study Protocol Published on:

  40. PD-L1 was an important biomarker in lung adenocarcinoma. The study was to confirm the most important factor affecting the expression of PD-L1 remains undetermined.

    Authors: Fang Lu, Ernuo Wang and Haiquan Liu
    Citation: BMC Cancer 2024 24:642
    Content type: Research Published on:

  41. HER2-positive, estrogen receptor-positive breast cancer (HER2+, ER+ BC) is a distinct disease subtype associated with inferior response to chemotherapy plus HER2-targeted therapy compared with HER2+, ER-negati...

    Authors: Sherko Kuemmel, Catherine Harper-Wynne, Yeon Hee Park, Fábio Franke, Michelino de Laurentiis, Eva Schumacher-Wulf, Daniel Eiger, Sarah Heeson, Andrés Cardona, Özgür Özyilkan, Flavia Morales-Vàsquez, Ciara Metcalfe, Marc Hafner, Eleonora Restuccia and Joyce O’Shaughnessy
    Citation: BMC Cancer 2024 24:641
    Content type: Study Protocol Published on:

  42. Pediatric Acute Myeloid Leukemia (AML) is a major cause of morbidity and mortality in children with cancer in Africa and other developing continents. Systemic chemotherapy and effective supportive care have si...

    Authors: Wudinesh Mamo, Ayalew Moges, Subah Abderehim Yesuf, Abdulkadir Mohamedsaid and Gashaw Arega
    Citation: BMC Cancer 2024 24:640
    Content type: Research Published on:

  43. Breast cancer patients often have a poor prognosis largely due to lack of effective targeted therapy. It is now well established that monosaccharide enhances growth retardation and chemotherapy sensitivity in ...

    Authors: Shilong Yu, Zhaoyi Yue and Qilun Liu
    Citation: BMC Cancer 2024 24:639
    Content type: Research Published on:

  44. Emerging evidence suggests the dysregulation of long non-coding RNAs (lncRNAs) involved in pancreatic cancer (PC). However, the function of LINC00930 in PC has not been elaborated. In this study, we found that...

    Authors: Yingqing Mao, Xian Su, Qingsong Guo, Xihao Yao, Qun Zhao, Yibing Guo, Yao Wang, Xiaohong Li and Yuhua Lu
    Citation: BMC Cancer 2024 24:638
    Content type: Research Published on:

  45. Brachytherapy has been indicated as an alternative option for treating cystic craniopharyngiomas (CPs). The potential benefits of brachytherapy for CPs have not yet been clarified. The purpose of this work was...

    Authors: Li-Yuan Zhang, Wei Guo, Han-Ze Du, Hui Pan, Yun-Chuan Sun, Hui-Juan Zhu, Shuai-Hua Song, Xiao-Yuan Guo, Yue Jiang and Qian-Qian Sun
    Citation: BMC Cancer 2024 24:637
    Content type: Research Published on:

  46. Neuroendocrine carcinoma (NEC) originating from the endometrium is rare, and there is limited knowledge regarding its diagnosis and optimal management. In this study, we present our experience with 11 patients...

    Authors: Xueyan Liu, Yanpeng Tian, Shuping Yan, Hanlin Fu, Lulu Si, Tianjiao Lai, Meng Mao, Qian Wang, Jing Bai, Heli Li and Ruixia Guo
    Citation: BMC Cancer 2024 24:636
    Content type: Research Published on:

  48. Patients with irresectable stage III or metastatic melanoma presenting with poor prognostic factors are usually treated with a combination of immune checkpoint inhibitors (ICIs), consisting of ipilimumab and n...

    Authors: J. C. Janssen, B. van Dijk, K. de Joode, M. J. B. Aarts, F. W. P. J. van den Berkmortel, C. U. Blank, M. J. Boers-Sonderen, A. J. M. van den Eertwegh, J. W. B. de Groot, M. Jalving, M. J. A. de Jonge, A. Joosse, E. Kapiteijn, A. M. Kamphuis-Huismans, K. A. T. Naipal, D. Piersma…
    Citation: BMC Cancer 2024 24:632
    Content type: Study Protocol Published on:

  50. The 17-gene Genomic Prostate Score (GPS) test has been clinically employed to predict adverse prognosis in prostate cancer. In this meta-analysis, we aimed to evaluate the prognostic value of the 17-gene GPS i...

    Authors: Feilun Cui, Xuan Tang, Changfeng Man and Yu Fan
    Citation: BMC Cancer 2024 24:628
    Content type: Systematic Review Published on:

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