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  1. This study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion radiotherapy (CIRT) alone or as a boost strategy after photon radiatio...

    Authors: XiaoJun Li, YanShan Zhang, YanCheng Ye, SuQing Tian, TingChao Hu, HongYu Chai, TianE Zhang and Faxin Wen
    Citation: BMC Cancer 2024 24:837
  2. The clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale, population-based study aimed to comprehensively outline these traits and construct ...

    Authors: Tao Chang, Rui Zhang, Jiahao Gan, Yuan Yang, Yanhui Liu, Yan Ju, Xiaodong Niu and Qing Mao
    Citation: BMC Cancer 2024 24:836
  3. Extracellular heat shock protein 90 AA1(eHSP90α) is intricately linked to tumor progression and prognosis. This study aimed to investigate the difference in the value of eHSP90α in post-treatment response asse...

    Authors: Yingzhen Bian, Haizhou Liu, Jinglei Huang, Zhaorong Feng, Yanyan Lin, Jilin Li and Litu Zhang
    Citation: BMC Cancer 2024 24:835
  4. In this study, we aimed to identify the risk factors in patients with rectal anastomotic re-leakage and develop a prediction model to predict the probability of rectal anastomotic re-leakage after stoma closure.

    Authors: Yuegang Li, Gang Hu, Jinzhu Zhang, Wenlong Qiu, Shiwen Mei, Xishan Wang and Jianqiang Tang
    Citation: BMC Cancer 2024 24:834
  5. This study aimed to investigate the efficacy and safety of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) for primary prophylaxis of neutropenia in patients with cervical cance...

    Authors: Jing You, Yidi Yuan, Xiaoxuan Gu, Weihu Wang and Xiaofan Li
    Citation: BMC Cancer 2024 24:833
  6. Radiotherapy in patients with head and neck cancer fairly leads to xerostomia, profoundly affecting their quality of life. With limited effective preventive and therapeutic methods, attention has turned to exp...

    Authors: Mohammad Farhadi, Pedram Fadavi, Saleh Mohebbi and Farzad Taghizadeh-Hesary
    Citation: BMC Cancer 2024 24:832
  7. Listening to patient voices is critical, in terms of how people experience their condition as well as their treatment preferences. This research explored the patient journey, therapy attributes and goals among...

    Authors: Simon Fifer, Jenni Godsell, Stephen Opat, Nada Hamad, Masa Lasica, Cecily Forsyth, Louisa Morand, Erica Smeaton, Sharon Winton, Andrea Puig and Marija McGeachie
    Citation: BMC Cancer 2024 24:831
  8. Numerous epidemiological investigations have explored the impact of body composition on the effectiveness of immune checkpoint inhibitors (ICIs) in urological malignancies (UM) patients, yielding conflicting f...

    Authors: Wangbin Ma, Qiao Shi, Lilong Zhang, Zhendong Qiu, Tianrui Kuang, Kailiang Zhao and Weixing Wang
    Citation: BMC Cancer 2024 24:830

    The Correction to this article has been published in BMC Cancer 2024 24:844

  9. Most gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has significantly improved the survival of patients with GISTs. We aimed to evalu...

    Authors: Hui-Jen Tsai, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh…
    Citation: BMC Cancer 2024 24:828
  10. Hospitalisation  resulting from complications of systemic therapy and radiotherapy places a substantial burden on the patient, society, and healthcare system. To formulate preventive strategies and enhance pat...

    Authors: Rashidul Alam Mahumud, Md. Shahjalal, Padam Kanta Dahal, Md. Parvez Mosharaf, Mohammad Enamul Hoque and Olivia Wawryk
    Citation: BMC Cancer 2024 24:826
  11. Immune response is known to play an important role in local tumor control especially in renal cell carcinoma (RCC), which is considered highly immunogenic. For localized tumors, operative resection or local ab...

    Authors: Johanna Waidhauser, Anna-Katharina Gantner, Paola Schifano, Katharina Rippel, Stefan Schiele, Tim Tobias Arndt, Gernot Müller, Julie Steinestel, Andreas Rank and Thomas Kröncke
    Citation: BMC Cancer 2024 24:825
  12. Colorectal cancer (CRC) is ranked as the third most commonly diagnosed cancer and the third cause of cancer related deaths. CRC is greatly attributed to genetic and epigenetic mutations and immune dysregulatio...

    Authors: Marwa Matboli, Nourhan Hossam, Doaa Farag, Mohamed Hassan, Hanan Shehata, Marwa Aboelhussein, Nahed Ismail and Sanaa Eissa
    Citation: BMC Cancer 2024 24:824
  13. Approximately 40% of treated head and neck cancer (HNC) patients develop recurrence. The risk of recurrence declines with time from treatment. Current guidelines recommend clinical follow-up every two months f...

    Authors: Paul Nankivell, Piers Gaunt, Claire Gaunt, Julia Sissons, Evaggelia Liaskou, Yolande Jefferson, Tessa Fulton-Lieuw, Saloni Mittal and Hisham Mehanna
    Citation: BMC Cancer 2024 24:823

    The Correction to this article has been published in BMC Cancer 2024 24:861

  14. The PAROLE-Onco program was introduced in the province of Quebec, Canada in 2019. It integrates accompanying patients (APs), i.e., people who have been affected by cancer, into the clinical team as full member...

    Authors: Marie-Pascale Pomey, Monica Iliescu Nelea, Cécile Vialaron, Louise Normandin, Marie-Andrée Côté, Mado Desforges, Pénélope Pomey-Carpentier, Nesrine Adjtoutah, Israël Fortin, Isabelle Ganache, Catherine Régis, Zeev Rosberger, Danielle Charpentier, Lynda Bélanger, Michel Dorval, Djahanchah P. Ghadiri…
    Citation: BMC Cancer 2024 24:822
  15. The incidence of colorectal cancer (CRC) has been increasing in Sub-Saharan countries, including Ethiopia. However, the real mortality rate for CRC patients in Ethiopia has not been established. Therefore, thi...

    Authors: Zewdu Bishaw Aynalem, Abebaw Bires Adal, Temesgien Fentahun Ayele, Gashaw Melkie Bayeh, Almaw Genet Yeshiwas, Tadesse Miretie Dessie and Tilahun Degu Tsega
    Citation: BMC Cancer 2024 24:821
  16. Potentially modifiable risk factors for hepatocellular carcinoma (HCC) have been investigated in observational epidemiology studies in East Asian and European populations, whereas the causal associations of mo...

    Authors: Xiaoxia Wei, Chenglei Yang, Qiuling Lin, Moqin Qiu, Qiuping Wen, Zihan Zhou, Yanji Jiang, Peiqin Chen, Xiumei Liang, Ji Cao, Juan Tang, Yuying Wei, Hongping Yu and Yingchun Liu
    Citation: BMC Cancer 2024 24:820
  17. Authors: R. Vera, N. Castro, I. Labiano, A. Lecumberri, A. E. Huerta, H. Arasanz, I. Caseda, F. Ruiz-Pace, C. Viaplana, V. Arrazubi, I. Hernandez-Garcia, E. Mata, D. Gomez, S. Laguna, J. Suarez, I. Fernandez-De-los-Reyes…
    Citation: BMC Cancer 2024 24:819

    The original article was published in BMC Cancer 2024 24:668

  18. Glioma is the most common primary brain tumor with high mortality and disability rates. Recent studies have highlighted the significant prognostic consequences of subtyping molecular pathological markers using...

    Authors: Xian Xie, Chen Luo, Shuai Wu, Wanyu Qiao, Wei Deng, Lei Jin, Junfeng Lu, Linghao Bu, Hugues Duffau, Jie Zhang and Ye Yao
    Citation: BMC Cancer 2024 24:818
  19. Inflammation plays a pivotal role in the progression of prostate cancer (PCa). Several immune-inflammatory indices, including neutrophil to lymphocyte ratio (NLR), derived neutrophil to lymphocyte ratio (dNLR)...

    Authors: Zhipeng Wang, Haoyang Liu, Qiyu Zhu, Junru Chen, Jinge Zhao and Hao Zeng
    Citation: BMC Cancer 2024 24:817
  20. Anaplastic thyroid carcinoma (ATC) is a rare but highly aggressive thyroid cancer with poor prognosis. Killing cancer cells by inducing DNA damage or blockage of DNA repair is a promising strategy for chemothe...

    Authors: Jinyan Chai, Mengxue Su, Ruiguo Zhang, Ning Li, Yuanyuan Jia, Wei Zheng, Jian Tan, Qiang Jia, Huabing Sun and Zhaowei Meng
    Citation: BMC Cancer 2024 24:816
  21. Non-small cell lung cancer (NSCLC) is the primary reason for cancer-related deaths globally. Tertiary lymphoid structure (TLS) is an organized collection of immune cells acquired in non-physiological, non-lymp...

    Authors: Luyuan Ma, Rongyang Li, Xiaomeng Liu, Wenhao Yu, Zhanpeng Tang, Yi Shen and Hui Tian
    Citation: BMC Cancer 2024 24:815
  22. Despite a multimodal approach including surgery, chemo- and radiotherapy, the 5-year event-free survival rate for rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in childhood, remains very poor for...

    Authors: Simona Camero, Luisa Milazzo, Francesca Vulcano, Federica Ceccarelli, Paola Pontecorvi, Francesca Pedini, Alessandra Rossetti, Elena Sofia Scialis, Giulia Gerini, Fabrizio Cece, Silvia Pomella, Matteo Cassandri, Antonella Porrazzo, Enrico Romano, Claudio Festuccia, Giovanni Luca Gravina…
    Citation: BMC Cancer 2024 24:814
  23. Therapeutic options for early-stage hepatocellular carcinoma (HCC) in individual patients can be limited by tumor and location, liver dysfunction and comorbidities. Many patients with early-stage HCC do not re...

    Authors: Alan Wigg, Jonathan Tibballs, Richard Woodman, Katherine Stuart, Hien Le, Stuart K. Roberts, John K. Olynyk, Simone I. Strasser, Michael Wallace, Jarad Martin, Annette Haworth, Nicholas Hardcastle, Kee Fong Loo, Colin Tang, Yoo Young Lee, Julie Chu…
    Citation: BMC Cancer 2024 24:813
  24. Cancer has become the leading diabetes-related cause of death in high-income countries, and more knowledge is needed to clarify the impact of diabetes on site-specific cancers. The purpose of this study is to ...

    Authors: Jens Ejrnæs Tønder, Marie Louise Bønnelykke-Behrndtz, Tinne Laurberg, Eeva-Liisa Røssell and Martin Sollie
    Citation: BMC Cancer 2024 24:812
  25. The recurrence of papillary thyroid carcinoma (PTC) is not unusual and associated with risk of death. This study is aimed to construct a nomogram that combines clinicopathological characteristics and ultrasoun...

    Authors: Binqian Zhou, Jianxin Liu, Yaqin Yang, Xuewei Ye, Yang Liu, Mingfeng Mao, Xiaofeng Sun, Xinwu Cui and Qin Zhou
    Citation: BMC Cancer 2024 24:810
  26. Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive cancer characterized by an immunosuppressive microenvironment. Patients from specific ethnicities and population groups have poorer prognoses than other...

    Authors: Nnenna Elebo, Ebtesam A. Abdel-Shafy, Jones A. O. Omoshoro-Jones, Zanele Nsingwane, Ahmed A. A. Hussein, Martin Smith, Geoffrey Candy, Stefano Cacciatore, Pascaline Fru and Ekene Emmanuel Nweke
    Citation: BMC Cancer 2024 24:809
  27. Telemedicine is beneficial for improving treatment efficiency and reducing medical expenses of cancer patients. This study focuses on cancer patients participating in teleconsultations through a regional telem...

    Authors: Fangfang Cui, Xu Zhang, Xianying He, Dongqing Liu, Jinming Shi, Ming Ye, Linlin Wang, Yuntian Chu and Jie Zhao
    Citation: BMC Cancer 2024 24:808
  28. In 2020, uterine cervical cancer (UCC) was the 12th most common cancer among women in France and the 4th worldwide. French health authorities wanted to increase Human Papilloma Virus (HPV) vaccination and screeni...

    Authors: Fanny Serman, Gabrielle Lisembard, Maxence Sahraoui, Christophe Berkhout, Michaël Rochoy, Anthony Haro and Matthieu Calafiore
    Citation: BMC Cancer 2024 24:807
  29. Authors: Mélanie Casile, Gilles Albrand, Clément Lahaye, Benjamin Lebecque, Joévin Besombes, Céline Bourgne, Bruno Pereira, Sandrine Saugues, Caroline Jamot, Eric Hermet and Marc G. Berger
    Citation: BMC Cancer 2024 24:806

    The original article was published in BMC Cancer 2024 24:661

  30. Differentiation of glioma and solitary brain metastasis (SBM), which requires biopsy or multi-disciplinary diagnosis, remains sophisticated clinically. Histogram analysis of MR diffusion or molecular imaging h...

    Authors: Yifei Su, Rui Cheng, Jinxia Guo, Miaoqi Zhang, Junhao Wang, Hongming Ji, Chunhong Wang, Liangliang Hao, Yexin He and Cheng Xu
    Citation: BMC Cancer 2024 24:805
  31. Over the last decades, the therapeutic armamentarium of metastatic renal cell carcinoma (mRCC) has been revolutionized by the advent of tyrosin-kinase inhibitors (TKI), immune-checkpoint inhibitors (ICI), and ...

    Authors: Mimma Rizzo, Gaetano Pezzicoli, Valentina Tibollo, Andrea Premoli and Silvana Quaglini
    Citation: BMC Cancer 2024 24:804
  32. Trabectedin in combination with pegylated liposomal doxorubicin (PLD) is approved for the treatment of patients with platinum-sensitive relapsed ovarian cancer. Nevertheless, there is currently limited informa...

    Authors: María Jesús Rubio, Aránzazu Manzano, Luis Miguel de Sande, Purificación Estévez-García, María del Mar Gordon, Diego Soto de Prado, Blanca Hernando Fernández de Aranguiz, Eva M. Guerra-Alia, Anna Carbó-Bagué, Ignacio Romero, Miguel Corbellas, Alba González-Haba, Carlos E. Robles-Barraza, Jerónimo Martínez-García and Antonio González-Martín
    Citation: BMC Cancer 2024 24:803
  33. The period between cancer diagnosis and surgery presents an opportunity for trials to assess the feasibility of behaviour change interventions. However, this can be a worrying time for patients and may hinder ...

    Authors: Amelia Talbot, Susan A Jebb, Claire Foster, Alba X Realpe, Pete Wheatstone, Simon Buczacki and Dimitrios A Koutoukidis
    Citation: BMC Cancer 2024 24:802
  34. Lung cancer still ranks first in the mortality rate of cancer. Uric acid is a product of purine metabolism in humans. Its presence in the serum is controversial; some say that its high levels have a protective...

    Authors: Ping Lin, Linxiang Zhang, Xiaohui Tang and Jihuang Wang
    Citation: BMC Cancer 2024 24:801
  35. Drug resistance remains a significant challenge in the treatment of pancreatic cancer. The development of drug-resistant cell lines is crucial to understanding the underlying mechanisms of resistance and devel...

    Authors: Cheng Yu, Yuanhui Su, Xin Miao, Changpeng Chai, Huan Tang, Lu Li, Jianfeng Yi, Zhenzhen Ye, Hui Zhang, Zhao Hu, Luyang Chen, Ning Li, Hao Xu and Wence Zhou
    Citation: BMC Cancer 2024 24:800
  36. Craniopharyngioma (CP) is a rare malformational tumor characterized by high rates of recurrence and morbid obesity. However, the role of inflammatory mediators in obesity and the prognosis of patients with CP ...

    Authors: Youchao Xiao, Wentao Wu, Fangzheng Liu, Yanfei Jia, Lu Jin, Ning Qiao, Kefan Cai, Siming Ru, Lei Cao and Songbai Gui
    Citation: BMC Cancer 2024 24:799
  37. Many cancer survivors experience cancer-related cognitive impairment (CRCI), often with significant negative consequences across various life domains. Emerging evidence suggests that allowing additional time t...

    Authors: Darren Haywood, Frank D. Baughman, Evan Dauer, Jennifer Haywood, Susan Rossell and Nicolas H. Hart
    Citation: BMC Cancer 2024 24:798
  38. Patients with recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) have proven benefit from anti-programmed cell death 1 (anti-PD-1) monotherapy. Here, we retrospectively analyze the association of plasma...

    Authors: Shaoyan Lin, Huaqiang Zhou, Gang Chen, Jinhui Xue, Qianwen Liu, Jianing Li, Yanhua Yang, Yuanyuan Zhao, Hua Bao, Yan Huang, Yuxiang Ma and Hongyun Zhao
    Citation: BMC Cancer 2024 24:797
  39. The incidence of Hodgkin's lymphoma (HL) in people living with HIV (PLWHA) and on HAART is approximately 20–30 times higher than in HIV-negative individuals. Most patients with HIV-HL present at an advanced st...

    Authors: Mercy M. Mbai, Emmanuel Mduma, Samuel Thuo, Eulade Rugengamanzi, Christina V. Malichewe and Emmanuel L. Lugina
    Citation: BMC Cancer 2024 24:796
  40. Oral Squamous Cell Carcinoma (OSCC) presents significant diagnostic challenges in its early and late stages. This study aims to utilize preoperative MRI and biochemical indicators of OSCC patients to predict t...

    Authors: Wen Li, Yang Li, Shiyu Gao, Nengwen Huang, Ikuho Kojima, Taro Kusama, Yanjing Ou, Masahiro Iikubo and Xuegang Niu
    Citation: BMC Cancer 2024 24:795
  41. Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal role in maintaining skin homeostasis. In cancer, KLK...

    Authors: Simon Kind, Carolina Palacios Castillo, Ria Schlichter, Natalia Gorbokon, Maximilian Lennartz, Lisa S. Hornsteiner, Sebastian Dwertmann Rico, Viktor Reiswich, Florian Viehweger, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Franziska Büscheck, Till S. Clauditz, Christoph Fraune, Andrea Hinsch…
    Citation: BMC Cancer 2024 24:794
  42. Accurate regulation of gene expression is crucial for normal development and function of cells. The prognostic significance and potential carcinogenic mechanisms of the related gene JARID2 in OSCC are not yet ...

    Authors: Yuxi Cheng, Zhengzheng Song, Jingyi Cheng and Zhangui Tang
    Citation: BMC Cancer 2024 24:793
  43. The in vivo functions of SerpinB2 in tumor cells and tumor-associated macrophages (TAMs) during breast cancer development and metastasis remain elusive. SerpinB2-deficient MMTV-PyMT mice (PyMTSB2−/−) were previou...

    Authors: Yin Ji Piao, Hoe Suk Kim, Hyelim Kim, Jun Shen and Woo Kyung Moon
    Citation: BMC Cancer 2024 24:792
  44. Early screening and detection of lung cancer is essential for the diagnosis and prognosis of the disease. In this paper, we investigated the feasibility of serum Raman spectroscopy for rapid lung cancer screen...

    Authors: Linfang Yan, Huiting Su, Jiafei Liu, Xiaozheng Wen, Huaichao Luo, Yu Yin and Xiaoqiang Guo
    Citation: BMC Cancer 2024 24:791
  45. Melanoma, a deadly form of skin cancer, has witnessed a notable increase in incidence over the past decades. Despite advancements in treatment, it remains a significant cause of cancer mortality. Understanding...

    Authors: Alexander J. Didier, Swamroop V. Nandwani, Dean Watkins, Alan M. Fahoury, Andrew Campbell, Daniel J. Craig, Divya Vijendra and Nancy Parquet
    Citation: BMC Cancer 2024 24:790
  46. MicroRNA-1 (miR-1) is a tumour suppressor that can inhibit cell proliferation and invasion in several cancer types. In addition, miR-1 was found to be associated with drug sensitivity. Circulating miRNAs have ...

    Authors: Jing Peng, Yanping Lin, Xiaonan Sheng, Chenwei Yuan, Yan Wang, Wenjin Yin, Liheng Zhou and Jinsong Lu
    Citation: BMC Cancer 2024 24:789
  47. Cancer is becoming a major health problem in Uganda. Cancer control requires accurate estimates of the cancer burden for planning and monitoring of the cancer control strategies. However, cancer estimates and ...

    Authors: Annet Nakaganda, Angela Spencer, Collins Mpamani, Cissy Nassolo, Sarah Nambooze, Henry Wabinga, Isla Gemmell, Andrew Jones, Jackson Orem and Arpana Verma
    Citation: BMC Cancer 2024 24:787

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