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  1. Glutathione S-transferase theta 1 (GSTT1) enzyme plays a key role in the neutralization of electrophilic compounds such as carcinogens. Herein, we aimed to evaluate GSTT1 deletion polymorphism and susceptibility ...

    Authors: Sepehr Sadafi, Parsia Choubsaz, Seyed Mohammad Mohyeddin Kazemeini, Mohammad Moslem Imani and Masoud Sadeghi
    Citation: BMC Cancer 2024 24:885
    Content type: Research Published on:

  2. Cancer stage at diagnosis is an important prognostic indicator for patient outcomes, with detection at later stages associated with increased mortality and morbidity. The impact of cancer stage on patient-repo...

    Authors: Karen C. Chung, Anushini Muthutantri, Grace G. Goldsmith, Megan R. Watts, Audrey E. Brown and Donald L. Patrick
    Citation: BMC Cancer 2024 24:884
    Content type: Research Published on:

  3. The role of miR-145-5p in non-small cell lung cancer (NSCLC) has been studied, however, the regulation of hBMSCs-derived exosomes (Exo) transmitted miR-145-5p in NSCLC was still unknown. This study aimed to in...

    Authors: Wu Yan, Haiyu Yang, Dekun Duan, Yufeng Wu, Youhu Liu, Jianping Mao, Yong Zhao and Junsong Ye
    Citation: BMC Cancer 2024 24:883
    Content type: Research Published on:

  4. Indigenous peoples worldwide experience inequitable cancer outcomes, and it is unclear if this is underpinned by differences in or inadequate use of endocrine treatment (ET), often used in conjunction with oth...

    Authors: Habtamu Mellie Bizuayehu, Sewunet Admasu Belachew, Shafkat Jahan, Abbey Diaz, Siddhartha Baxi, Kalinda Griffiths and Gail Garvey
    Citation: BMC Cancer 2024 24:882
    Content type: Systematic Review Published on:

  5. Bladder cancer (BLCA) poses a significant global health challenge due to its high incidence, poor prognosis, and limited treatment options.

    Authors: Muhammad Sarfaraz Iqbal, Nimra Sardar, Kaoqing Peng, Layla A. Almutairi, Xialo Duan, Fouzia Tanvir, Kotb A. Attia, Gouhua Zeng and Di Gu
    Citation: BMC Cancer 2024 24:880
    Content type: Research Published on:

  6. Oxaliplatin-containing adjuvant chemotherapy yields a significant survival benefit in stage III colon cancer and is the standard of care. Simultaneously, it causes dose-dependent peripheral neuropathy that may...

    Authors: Colin Sue-Chue-Lam, Christine Brezden-Masley, Rinku Sutradhar, Amy Ying Xin Yu and Nancy Noel Baxter
    Citation: BMC Cancer 2024 24:878
    Content type: Research Published on:

  7. Inetetamab is the first domestically developed innovative anti-HER2 monoclonal antibody in China, proven effective and safe in HER2-positive advanced breast cancer. However, its efficacy and safety in neoadjuv...

    Authors: Mingxia Jiang, Yue Chai, Jiaxuan Liu, Maiyue He, Yipeng Wang, Xue Yang, Zeyu Xing, Mengqi Zhang, Shihan Zhou, Fei Ma, Jiayu Wang, Peng Yuan, Binghe Xu and Qiao Li
    Citation: BMC Cancer 2024 24:877
    Content type: Research Published on:

  8. Carboplatin and paclitaxel (CP) have been the standard of care for advanced/recurrent endometrial cancer (EC) for many years. However, this chemotherapy combination shows limited efficacy and recurrences often...

    Authors: Alexandra Leary, Purificación Estévez-García, Renaud Sabatier, Isabelle Ray-Coquard, Margarita Romeo, Pilar Barretina-Ginesta, Marta Gil-Martin, Elena Garralda, Joaquim Bosch-Barrera, Teresa Morán, Paloma Martin-Martorell, Ernest Nadal, Pere Gascón, Jordi Rodon, Jose M Lizcano, Pau Muñoz-Guardiola…
    Citation: BMC Cancer 2024 24:876
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2024 24:911

  9. The diagnosis of solitary pulmonary nodules has always been a difficult and important point in clinical research, especially granulomatous nodules (GNs) with lobulation and spiculation signs, which are easily ...

    Authors: Yanhua Wen, Wensheng Wu, Yuling Liufu, Xiaohuan Pan, Yingying Zhang, Shouliang Qi and Yubao Guan
    Citation: BMC Cancer 2024 24:875
    Content type: Research Published on:

  10. For patients with rectal cancer, the utilization of temporary ileostomy (TI) has proven effective in minimizing the occurrence of severe complications post-surgery, such as anastomotic leaks; however, some pat...

    Authors: Chenglin Tang, Fan He, Fuyu Yang, Defei Chen, Junjie Xiong, Yu Zou and Kun Qian
    Citation: BMC Cancer 2024 24:874
    Content type: Research Published on:

  11. In older patients, esophageal squamous cell carcinoma (ESCC) is difficult to treat using standard therapies, including surgery and cisplatin-based chemoradiotherapy. Paclitaxel (PTX) has radiosensitizing activ...

    Authors: Kenro Hirata, Kayo Yoshida, Chikatoshi Katada, Akinori Watanabe, Takahiro Tsushima, Toshifumi Yamaguchi, Sachiko Yamamoto, Hideki Ishikawa, Yasunori Sato, Chiyo K. Imamura, Yusuke Tanigawara, Yoshinori Ito, Ken Kato, Yuko Kitagawa and Yasuo Hamamoto
    Citation: BMC Cancer 2024 24:873
    Content type: Research Published on:

  12. The aim of this study was to assess the risk factors for anastomotic stricture in esophageal cancer patients undergoing esophagectomy. Esophageal anastomotic stricture is the most common long-term complication...

    Authors: Yuan Zhong, Ruijuan Sun, Wei Li, Weiqian Wang, Jianpeng Che, Linlin Ji, Bingrong Guo and Chunbo Zhai
    Citation: BMC Cancer 2024 24:872
    Content type: Systematic Review Published on:

  13. The management of locally recurrent gynecological carcinoma remains a challenge due to the limited availability of data. This study aims to share our institutional experience in using definitive radiotherapy (...

    Authors: Hui Cong, Xiaojing Yang, Zhaobin Li, Zhen Li, Shuchen Lin, Wei Jiang and Jie Fu
    Citation: BMC Cancer 2024 24:871
    Content type: Research Published on:

  14. Population-based cancer registries (PBCRs) are the primary source of information for cancer surveillance and monitoring. Currently, there are 30 active PBCRs in Brazil. The objective of this study was to analy...

    Authors: Diego Rodrigues Mendonça e Silva, Max Moura de Oliveira and Maria Paula Curado
    Citation: BMC Cancer 2024 24:870
    Content type: Research Published on:

  15. CD8+T cells secreting granzyme A (GZMA) can induce pyroptosis in tumor cells by effectively cleaving gasdermin B (GSDMB), which is stimulated by interferon-γ (IFN-γ). However, the interaction between GZMA-express...

    Authors: Jiayi Yang, Xinyi Ding, Zhang Fang, Shaoxian Wu, Maoling Yuan, Rongzhang Chen, Qinlan Xu, Xinran Gao, Haoyu Wu, Lujun Chen, Xiao Zheng and Jingting Jiang
    Citation: BMC Cancer 2024 24:869
    Content type: Research Published on:

  16. Cancer is a predominant cause of death globally. PHD-finger domain protein 5 A (PHF5A) has been reported to participate in various cancers; however, there has been no pan-cancer analysis of PHF5A. This study a...

    Authors: Qianqian Cheng, Wenbin Ji, Zhenyu Lv, Wei Wang, Zhaiyue Xu, Shaohua Chen, Wenting Zhang, Yu Shao, Jing Liu and Yan Yang
    Citation: BMC Cancer 2024 24:868
    Content type: Research Published on:

  17. To evaluate the safety and efficacy of the granisetron transdermal delivery system (GTDS) combined with Dexamethasone for preventing chemotherapy-induced nausea and vomiting (CINV) in patients receiving Capeci...

    Authors: Cong Wang, Zhansheng Jiang, Jie Zhang, Yan Zhuang, Lining Sun, Jing Zhang, Manman Quan, Lan Lan, Yanwei Li, Bin Wang, Zhanyu Pan and Zhuchen Yan
    Citation: BMC Cancer 2024 24:867
    Content type: Research Published on:

  18. The identification of viable tumors and radiation necrosis after stereotactic radiosurgery (SRS) is crucial for patient management. Tumor habitat analysis involving the grouping of similar voxels can identify ...

    Authors: Yun Hwa Roh, Ji Eun Park, Seo Young Park, Young Hyun Cho, Young-Hoon Kim, Sang Woo Song, Shinkyo Yoon and Ho Sung Kim
    Citation: BMC Cancer 2024 24:866
    Content type: Study Protocol Published on:

  19. One of the main side effects of radiation therapy to the head and neck region is altered taste sensation. This causes significant morbidity and has profound effects on the quality of life (QoL) of patients. Wh...

    Authors: Anja Dietze, Peter J. Neyer, Marlene M. Speth, Philipp Metzler, Olgun Elicin, Panagiotis Balermpas, Daniel M. Aebersold, Oliver Riesterer and Sonja Stieb
    Citation: BMC Cancer 2024 24:865
    Content type: Study Protocol Published on:

  20. Because the proportion of elderly individuals and the incidence of cancer worldwide are continually increasing, medical costs for elderly inpatients with cancer are being significantly increasing, which puts t...

    Authors: Lilin Zhang, Xijing Zhuang, Xiumei Yang, Feng Xu, Nan Wang, Zhanfang Guo, Junfeng Chen and Ding Ding
    Citation: BMC Cancer 2024 24:864
    Content type: Research Published on:

  21. Colorectal cancer (CRC) is a significant malignancy with widespread implications. Despite progress in surgical interventions for rectal cancer, improvements in overall prognosis remain disproportionate. Standa...

    Authors: Mandana Biniaz, Arash Moradi, Manouchehr Ghorbanpour Basit, Abdol-Azim Seddighi Pashaki, Arash Dehghan and Kamal Mohammadian
    Citation: BMC Cancer 2024 24:863
    Content type: Research Published on:

  22. The International Federation of Gynecology and Obstetrics (FIGO) 2023 staging system for endometrial cancer (EC) was released with incorporating histology, lympho-vascular space invasion, and molecular classif...

    Authors: Changmin Yu, Xinhui Yuan, Qianlan Yao, Yuyin Xu, Xiaoyan Zhou, Xin Hu, Huijuan Yang, Huaying Wang, Xiaoli Zhu and Yulan Ren
    Citation: BMC Cancer 2024 24:862
    Content type: Research Published on:

  23. Authors: Paul Nankivell, Piers Gaunt, Claire Gaunt, Julia Sissons, Evaggelia Liaskou, Yolande Jefferson, Tessa Fulton-Lieuw, Saloni Mittal and Hisham Mehanna
    Citation: BMC Cancer 2024 24:861
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2024 24:823

  24. Sarcopenia has been demonstrated to be adversely correlated with the prognosis of various cancers. Our study aimed to estimate the prognostic value of sarcopenia in conjunction with inflammatory indices [neutr...

    Authors: Ling Xiao, Yudi Liu, Xue Zhang, Xinyu Nie, Hansong Bai, Jiahua Lyu and Tao Li
    Citation: BMC Cancer 2024 24:860
    Content type: Research Published on:

  25. Adverse reactions are prone to occur in the early stage of chemotherapy and can negatively affect the dietary intake and nutritional status of breast cancer (BC) patients. Consequently, they need to participat...

    Authors: Han Tang, Wei Zhang, Haiyan Shen, Haili Tang, Min Cai, Tao Wang, Pei Yan, Liang Li, Yan Wang, Huadong Zhao and Lei Shang
    Citation: BMC Cancer 2024 24:859
    Content type: Study Protocol Published on:

  26. Colon cancer remains a major health concern worldwide, with genetic factors playing a crucial role in its development. Toll-like receptors (TLRs) has been implicated in various cancers, but their role in colon...

    Authors: Ang Li, Hui Gao, Hongjiao Wu, Yuning Xie, Zhenxian Jia, Zhenbang Yang, Zhi Zhang and Xuemei Zhang
    Citation: BMC Cancer 2024 24:858
    Content type: Research Published on:

  27. Many long noncoding RNAs (lncRNAs) with altered expression significantly influence colorectal cancer (CRC) progression and behavior. The functions of many lncRNAs in CRC are not clear yet. This study aimed to ...

    Authors: Xinzhi Miao, Fang Wang, Muhammad Amir Yunus, Ida Shazrina Ismail and Tianyun Wang
    Citation: BMC Cancer 2024 24:857
    Content type: Research Published on:

  28. Residual fibroglandular breast tissue (RFGT) following a mastectomy is associated with the remaining of occult breast cancer at the time of mastectomy as well as an increased local recurrence risk thereafter. ...

    Authors: Deutschmann Christine, Singer F. Christian, Korbatits Ricarda, Kraus Christine, Gschwantler-Kaulich Daphne, Leser Carmen, Marzogi Alaa, Pascal A.T. Baltzer, Helbich H. Thomas, Pfeiler Georg and Clauser Paola
    Citation: BMC Cancer 2024 24:856
    Content type: Research Published on:

  29. Retroperitoneal liposarcoma (RLPS) constitutes the majority of retroperitoneal sarcomas. While surgical resection remains the sole curative approach, determining the optimal surgical strategy for RLPS remains ...

    Authors: Dao-Ning Liu, Liang Yan, Zhong-Wu Li, Hai-Yue Wang, Xiu-Yun Tian, Ang Lv and Chun-Yi Hao
    Citation: BMC Cancer 2024 24:855
    Content type: Research Published on:

  30. Metabolic dysregulation is recognized as a significant hallmark of cancer progression. Although numerous studies have linked specific metabolic pathways to cancer incidence, the causal relationship between blo...

    Authors: Gujie Wu, Jun Liu, Haochun Shi, Binyang Pan, Min Li, Xiaolin Wang, Yao Li, Lin Cheng, Weigang Guo and Yiwei Huang
    Citation: BMC Cancer 2024 24:854
    Content type: Research Published on:

  31. Metformin, a widely prescribed antidiabetic drug, has shown several promising effects for cancer treatment. These effects have been shown to be mediated by dual modulation of the AMPK-mTORC1 axis, where AMPK a...

    Authors: Karen Griselda De la Cruz-López, Eduardo Alvarado-Ortiz, Heriberto A. Valencia-González, Fredy Omar Beltrán-Anaya, José María Zamora-Fuentes, Alfredo Hidalgo-Miranda, Elizabeth Ortiz-Sánchez, Jesús Espinal-Enríquez and Alejandro García-Carrancá
    Citation: BMC Cancer 2024 24:853
    Content type: Research Published on:

  32. Providing appropriate specialized treatment to the right patient at the right time is considered necessary in cancer management. Targeted therapy tailored to the genetic changes of each breast cancer patient i...

    Authors: Solmaz Sohrabei, Hamid Moghaddasi, Azamossadat Hosseini and Seyed Jafar Ehsanzadeh
    Citation: BMC Cancer 2024 24:852
    Content type: Research Published on:

  33. Immune checkpoint inhibitors, such as anti-programmed cell death-1 (PD-1) and PD-1 ligand-1 (PD-L1) antibodies, have achieved breakthrough results in improving long-term survival rates in lung cancer. Although...

    Authors: Yun Wang, Rujia Chen, Zhenzhou Guo, Wei Wei, Ting Wang, Renren Ouyang, Xu Yuan, Yutong Xing, Feng Wang, Shiji Wu and Hongyan Hou
    Citation: BMC Cancer 2024 24:851
    Content type: Research Published on:

  34. This study was designed to evaluate the effect of progesterone receptor (PR) status on the prognosis of advanced estrogen receptor (ER)-high human epidermal growth factor receptor 2 (HER2)-negative breast canc...

    Authors: Lin Jia, Junning Peng, Nan Sun, Hongying Chen, Zhenyu Liu, Wenhui Zhao, Qingyuan Zhang and Liru Li
    Citation: BMC Cancer 2024 24:850
    Content type: Research Published on:

  35. Numerous meta-analyses and clinical studies have shown that subtypes of immune cells are associated with the development of skin cancer, but it is not clear whether this association is causal or biased. Mendel...

    Authors: Wei Yin, Ruilei Li, Zhaoqi Zhang, Ying Wang, Xinghua Tang, Lin Zhu, Hong Yao and Ke Li
    Citation: BMC Cancer 2024 24:849
    Content type: Research Published on:

  36. Long noncoding RNAs (lncRNAs) play vital regulatory functions in non-small cell lung cancer (NSCLC). Cisplatin (DDP) resistance has significantly decreased the effectiveness of DDP-based chemotherapy in NSCLC ...

    Authors: Yunfeng Chen, Siyan Wu, Yu Han, Hai Shi, Jieqing Yuan and Wenjie Cui
    Citation: BMC Cancer 2024 24:848
    Content type: Research Published on:

  37. Significant concomitants of the sick role maladaptation in colorectal cancer (CRC) patients include inappropriate cognitions, emotional states, and overt conducts associated to disease. This protocol was devel...

    Authors: Xinxin Li, Xiaodan Wu, Chao Chen, Huaxiang Chao, Jingyue Xie, Qianqian Du and Meifen Zhang
    Citation: BMC Cancer 2024 24:847
    Content type: Study Protocol Published on:

  38. Despite evidence showing a connection between inflammation and endometrial cancer (EC) risk, the surveys on genetic correlation and cohort studies investigating the impact on long-term outcomes have yet to be ...

    Authors: Jing Wang, Zhichao Chen, Yaozhen Lai, Zebiao Ma, Luanhong Wang, Pier Luigi Fiori, Ciriaco Carru, Giampiero Capobianco and Li Zhou
    Citation: BMC Cancer 2024 24:846
    Content type: Research Published on:

  39. Early detection of cancer is a highly effective way to decrease cancer-related deaths. The purpose of this study was to determine the disparity in cognitive factors related to cancer screening uptake based on ...

    Authors: Mehdi Mirzaei-Alavijeh, Mahin Amini, Mehdi Moradinazar, Mehdi Eivazi and Farzad Jalilian
    Citation: BMC Cancer 2024 24:845
    Content type: Research Published on:

  41. Cancer is one of the leading causes of morbidity and mortality worldwide. Among all cancer types, breast cancer stands out as the most common and is characterized by distinct molecular characteristics. This di...

    Authors: Zemene Damtie, Niguss Cherie and Melaku Mekonnen Agidew
    Citation: BMC Cancer 2024 24:843
    Content type: Research Published on:

  42. Targeted therapy is now the standard of care in driver–oncogene-positive non-small cell lung cancer (NSCLC). Its initial clinical effects are remarkable. However, almost all patients experience treatment resis...

    Authors: Teppei Yamaguchi, Junichi Shimizu, Reiko Matsuzawa, Naohiro Watanabe, Yoshitsugu Horio and Yutaka Fujiwara
    Citation: BMC Cancer 2024 24:842
    Content type: Research Published on:

  43. Standard oral cancer chemotherapy (OCT) or targeted therapy (OTT) has expanded the treatment methods for hepatocellular carcinoma (HCC). However, its principal nonadherence causes a reduction in efficacy. We a...

    Authors: Thai Doan Ky, Nguyen Thi Loan, Nguyen Tien Thinh and Mai Thanh Binh
    Citation: BMC Cancer 2024 24:841
    Content type: Research Published on:

  44. Detection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we proposed a plasma cfDNA-based approach called TOTEM to detect and trace the c...

    Authors: Dalin Xiong, Tiancheng Han, Yulong Li, Yuanyuan Hong, Suxing Li, Xi Li, Wenhui Tao, Yu S. Huang, Weizhi Chen and Chunguang Li
    Citation: BMC Cancer 2024 24:840
    Content type: Research Published on:

  45. A few studies regarding the epidemiology and risk factors of Non-muscle Invasive Bladder Cancer (NMIBC) are reported from Sub-Saharan African countries (SSA), including Somalia, and the African literature is s...

    Authors: Abdikarim Hussein Mohamed, Khaled Ali Mohamed, Ertan Kayacan, Yassin Nur and Mohamed Abdikarim Nur-amin
    Citation: BMC Cancer 2024 24:839
    Content type: Research Published on:

  46. The National Comprehensive Cancer Network (NCCN) guideline recommends consideration of weekly cisplatin as an alternative option for patients with head and neck cancer undergoing definitive chemoradiation. How...

    Authors: Jas Virk, Jasmin Gill, Fatemeh Fekrmandi, Austin Iovoli, Mark Farrugia, Ayham Al-Afif, Kimberly Wooten, Vishal Gupta, Ryan McSpadden, Moni A. Kuriakose, Michael R. Markiewicz, Wesley L. Hicks Jr, Sung Jun Ma and Anurag K. Singh
    Citation: BMC Cancer 2024 24:838
    Content type: Research Published on:

  47. This study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion radiotherapy (CIRT) alone or as a boost strategy after photon radiatio...

    Authors: XiaoJun Li, YanShan Zhang, YanCheng Ye, SuQing Tian, TingChao Hu, HongYu Chai, TianE Zhang and Faxin Wen
    Citation: BMC Cancer 2024 24:837
    Content type: Research Published on:

  48. The clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale, population-based study aimed to comprehensively outline these traits and construct ...

    Authors: Tao Chang, Rui Zhang, Jiahao Gan, Yuan Yang, Yanhui Liu, Yan Ju, Xiaodong Niu and Qing Mao
    Citation: BMC Cancer 2024 24:836
    Content type: Research Published on:

  49. In this study, we aimed to identify the risk factors in patients with rectal anastomotic re-leakage and develop a prediction model to predict the probability of rectal anastomotic re-leakage after stoma closure.

    Authors: Yuegang Li, Gang Hu, Jinzhu Zhang, Wenlong Qiu, Shiwen Mei, Xishan Wang and Jianqiang Tang
    Citation: BMC Cancer 2024 24:834
    Content type: Research Published on:

  50. This study aimed to investigate the efficacy and safety of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) for primary prophylaxis of neutropenia in patients with cervical cance...

    Authors: Jing You, Yidi Yuan, Xiaoxuan Gu, Weihu Wang and Xiaofan Li
    Citation: BMC Cancer 2024 24:833
    Content type: Research Published on:

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