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  1. In low-resource settings with weak health systems, the WHO recommends clinical breast examination (CBE) as the most cost-effective breast screening modality for women. Evidence shows that biennial CBE leads to...

    Authors: Agani Afaya, Timothy Tienbia Laari, Abdul Aziz Seidu, Richard Adongo Afaya, Silas Selorm Daniels-Donkor, Vida Nyagre Yakong and Bright Opoku Ahinkorah
    Citation: BMC Cancer 2023 23:114
    Content type: Research Published on:

  2. The TROIKA trial established that HD201 and trastuzumab were equivalent in terms of primary endpoints (total pathological complete response) following neoadjuvant treatment. The objective of the present analys...

    Authors: Xavier Pivot, Alexey Georgievitch Manikhas, Volodymyr Shamrai, Giorgi Dzagnidze, Hwoei Fen Soo Hoo, Viriya Kaewkangsadan, Fausto Petrelli, Cristian Villanueva, Jamie Kim, Sumita Pradhan, Litha Jaison, Peggy Feyaerts, Leonard Kaufman, Marie-Paule Derde, Filip Deforce and David G. Cox
    Citation: BMC Cancer 2023 23:112
    Content type: Research Published on:

  4. Early diagnosis of lung adenocarcinoma (LUAD), one of the most common types of lung cancer, is very important to improve the prognosis of patients. The current methods can’t meet the requirements of early diag...

    Authors: Junfeng Li, Jianjie Li, Huifeng Hao, Fangliang Lu, Jia Wang, Menglei Ma, Bo Jia, Minglei Zhuo, Jingjing Wang, Yujia Chi, Xiaoyu Zhai, Yuyan Wang, Meina Wu, Tongtong An, Jun Zhao, Fan Yang…
    Citation: BMC Cancer 2023 23:110
    Content type: Research Published on:

  5. Transcatheter arterial embolization (TAE) has long been used for hemostasis of traumatic or postoperative hemorrhage and embolization of tumors. Previous retrospective studies of TAE for painful bone metastase...

    Authors: Sadamoto Zenda, Yasunori Arai, Shunsuke Sugawara, Yoshitaka Inaba, Kazuki Hashimoto, Kouji Yamamoto, Yusuke Saigusa, Takashi Kawaguchi, Sanae Shimada, Marie Yokoyama, Tempei Miyaji, Tomoka Okano, Naoki Nakamura, Eisuke Kobayashi, Tatsuya Takagi, Yoshihisa Matsumoto…
    Citation: BMC Cancer 2023 23:109
    Content type: Study protocol Published on:

  6. As the dominant component of the tumor microenvironment, cancer-associated fibroblasts (CAFs), play a vital role in tumor progression. An increasing number of studies have confirmed that CAFs are involved in a...

    Authors: Zhiyang Zhou, Sixuan Guo, Shuhui Lai, Tao Wang, Yao Du, Junping Deng, Shun Zhang, Ge Gao and Jiangnan Zhang
    Citation: BMC Cancer 2023 23:108
    Content type: Research Published on:

  8. A more effective immune response against glioblastoma is needed in order to achieve better tumor control. Radiotherapy can induce anti-tumor mediated immune reactions, in addition to its dose response effects....

    Authors: Emma Liljedahl, Elise Konradsson, Emma Gustafsson, Karolina Förnvik Jonsson, Jill K. Olofsson, Kurt Osther, Crister Ceberg and Henrietta Nittby Redebrandt
    Citation: BMC Cancer 2023 23:106
    Content type: Research Published on:

  9. Cuproptosis, an emerging form of programmed cell death, has recently been identified. However, the association between cuproptosis-related long non-coding RNA (lncRNA) signature and the prognosis in prostate c...

    Authors: Xiaofeng Cheng, Zhenhao Zeng, Heng Yang, Yujun Chen, Yifu Liu, Xiaochen Zhou, Cheng Zhang and Gongxian Wang
    Citation: BMC Cancer 2023 23:105
    Content type: Research Published on:

  10. To explore the potential pathogenesis and clinical features of second primary glioblastoma (spGBM) following first primary renal cell carcinoma (fpRCC).

    Authors: Guang-Tao Zhang, Qi Liu, Fu-Xing Zuo, Hou-Jie Liu, Song-Quan Wang, Qing Yuan, Ang-Si Liu, Ke Hu, Xiao-Li Meng, Wei-Jia Wang, Hai-Peng Qian, Jing-Hai Wan and Hong-Qing Cai
    Citation: BMC Cancer 2023 23:104
    Content type: Research Published on:

  11. Real-world data of Palbociclib are insufficient in China. This study aimed to investigate the treatment pattern and real-world outcomes in hormone receptor positive and human epidermal growth factor 2 receptor...

    Authors: Jiao Yang, Bing Zhao, Xiaoling Ling, Donghui Li, Jiuda Zhao, Yonggang Lv, Guangxi Wang, Xinlan Liu, Nanlin Li and Jin Yang
    Citation: BMC Cancer 2023 23:103
    Content type: Research Published on:

  12. CD276 (also known as B7-H3) is one of the most important immune checkpoints of the CD28 and B7 superfamily, and its abnormal expression is closely associated with various types of cancer. It has been shown that C...

    Authors: Lirui Dai, Xuyang Guo, Zhe Xing, Yiran Tao, Wulong Liang, Zimin Shi, Weihua Hu, Shaolong Zhou and Xinjun Wang
    Citation: BMC Cancer 2023 23:102
    Content type: Research Published on:

  13. Systemic inflammation is crucial for the development and progression of cancers. The advanced lung cancer inflammation index (ALI) is considered to be a better indicator of systemic inflammation than current b...

    Authors: Lilong Zhang, Kailiang Zhao, Tianrui kuang, Kunpeng Wang, Dongqi Chai, Zhendong Qiu, Rongqiang Liu, Wenhong Deng and Weixing Wang
    Citation: BMC Cancer 2023 23:101
    Content type: Research Published on:

  14. The aim of this paper was to clarify the optimal minimum number of lymph node for CEA-elevated (≥ 5 ng/ml) colon cancer patients.

    Authors: Hao Zhang, Chunlin Wang, Yunxiao Liu, Hanqing Hu, Qingchao Tang, Rui Huang, Meng Wang and Guiyu Wang
    Citation: BMC Cancer 2023 23:100
    Content type: Research Published on:

  15. Both Red Blood Cell (RBC) transfusion and anemia are thought to negatively impact cancer survival. These effects have been reported with mixed findings in cancer of the esophagus. The potential impact of the a...

    Authors: Joseph P. Connor, Eric Destrampe, Daniel Robbins, Aaron S. Hess, Daniel McCarthy and James Maloney
    Citation: BMC Cancer 2023 23:99
    Content type: Research Published on:

  16. To compare the effectiveness of high-resolution dermal ultrasound (US) guided superficial radiotherapy (SRT) to non-image-guided radiotherapy in the treatment of early-stage Non-Melanoma Skin Cancer (NMSC).

    Authors: Lio Yu, Mairead Moloney, Songzhu Zheng and James Rogers
    Citation: BMC Cancer 2023 23:98
    Content type: Research Published on:

  17. Distant metastasis remains the main cause of death in breast cancer. Breast cancer risk is strongly influenced by pathogenic mutation.This study was designed to develop a multiple-feature model using clinicopa...

    Authors: Zhenzhen Shao, Jinpu Yu, Yanan Cheng, Wenjuan Ma, Peifang Liu and Hong Lu
    Citation: BMC Cancer 2023 23:97
    Content type: Research Published on:

  18. High expression of SETD1A, a histone methyltransferase that specifically methylates H3K4, acted as a key oncogene in several human cancers. However, the function and underlying molecular mechanism of SETD1A in...

    Authors: Hongjuan Chai, Chunpeng Pan, Mingyang Zhang, Haizhong Huo, Haiyan Shan and Jugang Wu
    Citation: BMC Cancer 2023 23:96
    Content type: Research Published on:

  19. To evaluate the overall survival (OS), disease-specific survival (DSS), and recurrence-free survival (RFS) for primary cervical lymphoma (PCL), an extremely rare disease without treatment consensus.

    Authors: Lingyun Gao, Xiaoran Chen, Jing Zhao, Anli Xu, Meijuan Liu, Hongna Yu, Shujun Kong and Sijian Li
    Citation: BMC Cancer 2023 23:95
    Content type: Research Published on:

  20. PRECONNECT was an international, phase IIIb trial evaluating the safety and efficacy of trifluridine/tipiracil (FTD/TPI) for metastatic colorectal cancer (mCRC).

    Authors: Julien Taieb, Timothy Price, Loïck Vidot, Bénédicte Chevallier, Lucjan Wyrwicz and Jean-Baptiste Bachet
    Citation: BMC Cancer 2023 23:94
    Content type: Research Published on:

  21. This retrospective study explored the relationship between hormone receptor (HR), human epidermal growth factor receptor 2 (HER2) status, and bone involvement in the first distant metastases (DM) of Chinese br...

    Authors: Zhifeng Jia, Muwei Dai, Yuguang Shang, Yue Li and Zhensheng Li
    Citation: BMC Cancer 2023 23:93
    Content type: Research Published on:

  22. Understanding the latest global spatio-temporal pattern of prostate cancer burden attributable to smoking can help guide effective global health policy. This study aims to elucidate the trends in smoking-relat...

    Authors: Hanfei Zhang, Dingping Huang, Yingfeng Zhang, Xia Wang, Jiangtao Wu and Daqing Hong
    Citation: BMC Cancer 2023 23:92
    Content type: Research Published on:

  25. Ovarian cancer is a leading cause of female mortality. Epigenetic changes occur in early stages of carcinogenesis and represent a marker for cancer diagnosis. Protocadherin 17 (PCDH17) is a tumor suppressor gene ...

    Authors: Sherif Mohamed Elsharkawi, Dalal Elkaffash, Pacint Moez, Nour El-Etreby, Eman Sheta and Raghda Saad Zaghloul Taleb
    Citation: BMC Cancer 2023 23:89
    Content type: Research Published on:

  26. Magnetic resonance imaging (MRI) performs well in the locoregional assessment of extranodal nasal-type NK/T-cell lymphoma (ENKTCL). It’s important to assess the value of multi-modal MRI-based radiomics for est...

    Authors: Yu-Ting Zhao, Si-Ye Chen, Xin Liu, Yong Yang, Bo Chen, Yong-Wen Song, Hui Fang, Jing Jin, Yue-Ping Liu, Hao Jing, Yuan Tang, Ning Li, Ning-Ning Lu, Shu-Lian Wang, Han Ouyang, Chen Hu…
    Citation: BMC Cancer 2023 23:88
    Content type: Research Published on:

  27. Insulin-like growth factor-1 receptor (IGF-1R) promotes cell proliferation and migration and inhibitsapoptosis, all of which can contribute to the development of cancers.

    Authors: Wenpeng Cai, Yongfang Ma, Li Song, Niandie Cao, Jiafeng Gao, Shuping Zhou and Xiaolong Tang
    Citation: BMC Cancer 2023 23:87
    Content type: Research Published on:

  28. Tumor micronecrosis is a histopathological feature predicting poor prognosis in patients with hepatocellular carcinoma (HCC) who underwent liver resection. However, the role of tumor micronecrosis in liver tra...

    Authors: Yangyang Wang, Wei Zhang, Hongbin Ge, Xu Han, Jiangchao Wu, Xuqi Sun, Ke Sun, Wanyue Cao, Chao Huang, Jingsong Li, Qi Zhang and Tingbo Liang
    Citation: BMC Cancer 2023 23:86
    Content type: Research Published on:

  29. While molecular targeted drugs and other therapies are being developed for many tumors, pancreatic cancer is still considered to be the malignant tumor with the worst prognosis. We started this study to identi...

    Authors: Shoichiro Tange, Tomomi Hirano, Masashi Idogawa, Eishu Hirata, Issei Imoto and Takashi Tokino
    Citation: BMC Cancer 2023 23:85
    Content type: Research Published on:

  30. Breast cancer patients of American Society of Clinical Oncology and the College of American Pathologists (ASCO/CAP) Group 2 were all HER2-negative according to the 2018 guideline, not HER2-positive as defined ...

    Authors: Shuling Zhou, Hong Lv, Anqi Li, Ming Li, Siyuan Zhong, Hongfen Lu, Xiaoyan Zhou, Qianming Bai and Wentao Yang
    Citation: BMC Cancer 2023 23:84
    Content type: Research Published on:

  31. Programmed Cell Death-1/ Programmed Death-ligand 1 (PD-1 / PD-L1) inhibitor therapies targeting immunocytes induce persistent tumor remission in various cancers. However, the appropriate biomarkers for the the...

    Authors: Xiaoyue Du, Shaodi Wen, Run Shi, Jingwei Xia, Ruotong Wang, Yihan Zhang, Banzhou Pan, Xiaoliu Wu, Wei Zhu, Jifeng Feng, Xin Wang and Bo Shen
    Citation: BMC Cancer 2023 23:83
    Content type: Research Published on:

  32. Mastocytosis is a very rare disorder and is divided into three prognostically distinct variants by World Health Organization: Cutaneous mastocytosis (CM), systemic mastocytosis (SM), and mast cell sarcoma or l...

    Authors: Tarık Onur Tiryaki, Sıdıka Gülkan Özkan, Simge Erdem, Aynur Dağlar Aday, İpek Yönal Hindilerden, Aslı Gelincik, Can Baykal, Gülçin Yegen, İbrahim Öner Doğan, Nesimi Büyükbabani, Meliha Nalçacı and Akif Selim Yavuz
    Citation: BMC Cancer 2023 23:82
    Content type: Research Published on:

  33. Childhood cancer (CC) is a leading cause of death among children aged 0–19 years worldwide. Each year, 400,000 new cases of CC are diagnosed globally. Given the between-country differences in CC incidence rate...

    Authors: Manushak Avagyan, Anahit Demirchyan and Lusine Abrahamyan
    Citation: BMC Cancer 2023 23:81
    Content type: Research Published on:

  34. Smoking is a modifiable risk factor for cancers. The aim of the study is to estimate the trend of mortality and DALYs of smoking-attributed cancers in the North Africa and Middle East (NAME) countries.

    Authors: Leila Rezakhani, Mitra Darbandi, Zahra Khorrami, Shima Rahmati and Fatemeh Khosravi Shadmani
    Citation: BMC Cancer 2023 23:80
    Content type: Research Published on:

  35. Cervical cancer is currently estimated to be the fourth most common cancer among women worldwide and the leading cause of cancer-related deaths in some of the world’s poorest countries. C/EBPβ has tumor suppre...

    Authors: Haichen Long, Yangyang Li, Huijuan Wang, Bingxuan Guo, Shuyan Song, Xiangyi Zhe, Hongtao Li, Dongmei Li, Renfu Shao and Zemin Pan
    Citation: BMC Cancer 2023 23:79
    Content type: Research Published on:

  36. Incidence and risk factors for seizures among women with advanced breast cancer (BC) and brain metastases are not well characterized across treatment-related or clinical subtypes. This study leveraged a large ...

    Authors: Alexander Liede, Wendy Sebby, Ashok Kumar Reddy Miriyala, Ravi Potluri, Debasish Mazumder, Anirban Ghosh, Eros Papademetriou, Ryan Kilpatrick and Jerzy E. Tyczynski
    Citation: BMC Cancer 2023 23:78
    Content type: Research Published on:

  37. Precision medicine with gene panel testing based on next-generation sequencing for patients with cancer is being used increasingly in clinical practice. HER2, which encodes the human epidermal growth factor recep...

    Authors: Yohei Harada, Akemi Sato, Hideaki Nakamura, Keita Kai, Sho Kitamura, Tomomi Nakamura, Yuki Kurihara, Sadakatsu Ikeda, Eisaburo Sueoka, Shinya Kimura and Naoko Sueoka-Aragane
    Citation: BMC Cancer 2023 23:77
    Content type: Research Published on:

  38. Gastric cancer peritoneal metastasis (GCPM) is an important cause of cancer-related deaths worldwide. Long non-coding RNAs (lncRNAs) play a key role in the regulation of GCPM, but the underlying mechanisms hav...

    Authors: Chao Dong, Fujuan Luan, Wenyan Tian, Kaipeng Duan, Tao Chen, Jiayu Ren, Weikang Li, Dongbao Li, Qiaoming Zhi and Jin Zhou
    Citation: BMC Cancer 2023 23:76
    Content type: Research Published on:

  40. Patients with follicular lymphoma (FL) can have high response rates to early lines of treatment. However, among FL patients relapsed/refractory (r/r) after ≥2 prior lines of therapy (LOT), remission tends to b...

    Authors: Steve Kanters, Graeme Ball, Brad Kahl, Adriana Wiesinger, Eve H. Limbrick-Oldfield, Akshay Sudhindra, Julia Thornton Snider and Anik R. Patel
    Citation: BMC Cancer 2023 23:74
    Content type: Research Published on:

  41. Stereotactic Body Radiation Therapy (SBRT) has been found beneficial for adrenal gland metastases (AGMs) with a high local control rate and low toxicity. The role of SBRT for AGMs in patients with liver cancer...

    Authors: Bichun Xu, Xianzhi Zhao, Di Chen, Wenjuan Zhao, Xiaoyan Wang, Changhua Ding, Zhiyong Yuan and Huojun Zhang
    Citation: BMC Cancer 2023 23:73
    Content type: Research Published on:

  42. “Anti-angiogenetic drugs plus chemotherapy” (anti-angio-chemo) and “immune checkpoint inhibitors plus chemotherapy” (ICI-chemo) are superior to traditional chemotherapy in the first-line treatment of patients ...

    Authors: Lan-Lan Pang, Jia-Di Gan, Yi-Hua Huang, Jun Liao, Wei-Tao Zhuang, Wael-Abdullah-Sultan Ali, Shao-Dong Hong, Li Zhang and Wen-Feng Fang
    Citation: BMC Cancer 2023 23:72
    Content type: Research article Published on:

  43. Chronic infection with Kaposi’s sarcoma-associated herpes virus (KSHV) in B lymphocytes causes primary effusion lymphoma (PEL), the most aggressive form of KSHV-related cancer, which is resistant to convention...

    Authors: Tetsunori Sakamoto, Masahiko Ajiro, Akira Watanabe, Shingo Matsushima, Keiji Ueda and Masatoshi Hagiwara
    Citation: BMC Cancer 2023 23:71
    Content type: Research Published on:

  44. Authors: D. Doppenberg, M. G. Besselink, C. H. J. van Eijck, M. P. W. Intven, B. Groot Koerkamp, G. Kazemier, H. W. M. van Laarhoven, M. Meijerink, I. Q. Molenaar, J. J. M. E. Nuyttens, R. van Os, H. C. van Santvoort, G. van Tienhoven, H. M. Verkooijen, E. Versteijne, J. W. Wilmink…
    Citation: BMC Cancer 2023 23:70
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2022 22:1363

  45. The initial management of patients with sarcoma is a critical issue. We used the nationwide French National Cancer Institute-funded prospective sarcoma database NETSARC to report the management and oncologic outc...

    Authors: Pierre Kubicek, Axel Le Cesne, Cyril Lervat, Maud Toulmonde, Christine Chevreau, Florence Duffaud, Louis-Romée Le Nail, Magali Morelle, Nathalie Gaspar, Cécile Vérité, Marie-Pierre Castex, Nicolas Penel, Esma Saada, Sylvain Causeret, François Bertucci, Christophe Perrin…
    Citation: BMC Cancer 2023 23:69
    Content type: Research Published on:

  46. Nanoliposomal irinotecan plus fluorouracil/leucovorin (5-FU/LV) is a standard second-line therapy for patients with pancreatic cancer. Identification of biomarkers is important to determine appropriate treatme...

    Authors: Takeshi Kawakami, Akiko Todaka, Kotoe Oshima, Kunihiro Fushiki, Satoshi Hamauchi, Takahiro Tsushima, Tomoya Yokota, Yusuke Onozawa, Hirofumi Yasui and Kentaro Yamazaki
    Citation: BMC Cancer 2023 23:68
    Content type: Research Published on:

  47. Little is known about dementia’s impact on patterns of diagnosis, treatment, and outcomes in cancer patients. This study aimed to elucidate the differences in cancer staging, treatment, and mortality in older ...

    Authors: Toshitaka Morishima, Yoshihiro Kuwabara, Mari Kajiwara Saito, Satomi Odani, Haruka Kudo, Mizuki Kato, Kayo Nakata and Isao Miyashiro
    Citation: BMC Cancer 2023 23:67
    Content type: Research article Published on:

  48. Historically, high hepatocellular carcinoma (HCC)–related mortality has been, in part, due to lack of effective therapies; however, several systemic therapies have been recently approved for HCC treatment, inc...

    Authors: Neehar D. Parikh, Allicia Girvan, Joshua Coulter, Jonathon Gable, Jiat Ling Poon, Sangmi Kim, Anindya Chatterjee and Marco Boeri
    Citation: BMC Cancer 2023 23:66
    Content type: Research Published on:

  49. Advances in multiple myeloma treatment and a proliferation of treatment options have resulted in improved survival rates and periods of symptom-free remission for many multiple myeloma patients. As a result, h...

    Authors: Carrie Dombeck, Teresa Swezey, Juan Marcos Gonzalez Sepulveda, Bryce B. Reeve, Thomas W. LeBlanc, David Chandler and Amy Corneli
    Citation: BMC Cancer 2023 23:65
    Content type: Research Published on:

  50. Duke pancreatic mono-clonal antigen type 2 (DUPAN-II) is a famous tumour maker for pancreatic cancer (PC) as well as carbohydrate antigen 19–9 (CA19-9). We evaluated the clinical implications of DUPAN-II level...

    Authors: Shinichiro Hasegawa, Hidenori Takahashi, Hirofumi Akita, Yosuke Mukai, Manabu Mikamori, Kei Asukai, Daisaku Yamada, Hiroshi Wada, Yoshiaki Fujii, Takahito Sugase, Masaaki Yamamoto, Tomohira Takeoka, Naoki Shinno, Hisashi Hara, Takashi Kanemura, Naotsugu Haraguchi…
    Citation: BMC Cancer 2023 23:63
    Content type: Research Published on:

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