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  1. The current National Comprehensive Cancer Network (NCCN) guidelines recommend that at least 16 lymph nodes should be examined for gastric cancer patients to reduce staging migration. However, there is still de...

    Authors: Lulu Zhao, Fan Zhang, Fuzhi Jiao, Xiadong Zhou, Penghui Niu, Xue Han, Wanqing Wang, Xiaoyi Luan, Mingyan He, Quanlin Guan, Yumin Li, Dongbing Zhao, Jidong Gao and Yingtai Chen
    Citation: BMC Cancer 2023 23:892
    Content type: Research Published on:

  2. For patients with pancreatic ductal adenocarcinoma (PDAC), surgical resection remains the only potentially curative treatment. Surgery is generally followed by postoperative chemotherapy associated with improv...

    Authors: Christelle Bouchart, Julie Navez, Ivan Borbath, Karen Geboes, Timon Vandamme, Jean Closset, Luigi Moretti, Pieter Demetter, Marianne Paesmans and Jean-Luc Van Laethem
    Citation: BMC Cancer 2023 23:891
    Content type: Study Protocol Published on:

  3. The expansion of antiretroviral therapy (ART) eligibility could lead to earlier initiation of Human Immunodeficiency Virus (HIV) treatment and consequently reduce the risk of HIV-associated Kaposi Sarcoma (KS)...

    Authors: Maxwell. O. Akanbi, Lucy. A. Bilaver, Chad Achenbach, Lisa. R. Hirschhorn, Adovich. S. Rivera, Orimisan. S. Adekolujo, Kehinde. U. A. Adekola, Olugbenga. A. Silas, Patricia. A. Agaba, Oche Agbaji, Nathan. Y. Shehu, Solomon. A. Sagay, Lifang Hou and Robert. L. Murphy
    Citation: BMC Cancer 2023 23:890
    Content type: Research Published on:

  4. Exerkines are all peptides, metabolites, and nucleic acids released into the bloodstream during and after physical exercise. Exerkines liberated from skeletal muscle (myokines), the heart (cardiokines), liver ...

    Authors: Amirhossein Ahmadi Hekmatikar, André Nelson and Aaron Petersen
    Citation: BMC Cancer 2023 23:889
    Content type: Review Published on:

  5. Endometrial carcinoma (EC) is one of the most commonly diagnosed gynecologic malignancy in China. However, the genetic profile of Chinese EC patients has not been well established yet.

    Authors: Jin Li, Xiaoqi Li, Chenlian Quan, Xiaoqiu Li, Chong Wan and Xiaohua Wu
    Citation: BMC Cancer 2023 23:888
    Content type: Research Published on:

  6. The relationship between migraine and breast cancer risk has generated conflicting findings. We attempted to assess the association between migraine and breast cancer risk using Mendelian randomization (MR) an...

    Authors: Tian Fang, Zhihao Zhang, Huijie Zhou, Wanchun Wu, Fuqing Ji and Liqun Zou
    Citation: BMC Cancer 2023 23:887
    Content type: Research Published on:

  7. Glioblastoma (GBM), a prevalent and malignant brain tumor, poses a challenge in surgical resection due to its invasive nature within the brain parenchyma. CDKN1A (p21, Waf-1), a cyclin-dependent kinase inhibit...

    Authors: Wen-Yu Cheng, Chiung-Chyi Shen, Yea-Jiuen Liang, Ming-Tsang Chiao, Yi-Chin Yang, Wan-Yu Hsieh, Cheng-Hui Lin and Jun-Peng Chen
    Citation: BMC Cancer 2023 23:886
    Content type: Research Published on:

  8. Bladder and urinary tract cancers account for approximately 21,000 new diagnoses and 5,000 deaths annually in the UK. Approximately 90% are transitional cell carcinomas where advanced disease is treated with p...

    Authors: Simon Crabb, Robin Wickens, Sarah Jane-Bibby, Denise Dunkley, Megan Lawrence, Allen Knight, Robert Jones, Alison Birtle, Robert Huddart, Mark Linch, Jonathan Martin, Adam Coleman, Konstantinos Boukas, Hannah Markham and Gareth Griffiths
    Citation: BMC Cancer 2023 23:885
    Content type: Study Protocol Published on:

  9. The relationship between sleep disturbances and lung cancer is complex and bidirectional. This meta-epidemiological study aimed to explore the potential association between sleep disruption and the risk of pul...

    Authors: Tong Zhou, Zichen Wang, Chenxi Qiao, Shuo Wang, Shuaihang Hu, Xinyan Wang, Xiumei Ma, Dandan Wang, Jinglei Li, Zheng Li and Wei Hou
    Citation: BMC Cancer 2023 23:884
    Content type: Research Published on:

  10. Triple negative breast cancers (TNBC) account for approximately 15% of all breast cancers and are associated with a shorter median survival mainly due to locally advanced tumor and high risk of metastasis. The...

    Authors: Jordane Divoux, Romane Florent, Margaux Jacobs, Justine Lequesne, Jean-Michel Grellard, Chankannira San, Sara Grossi, Katia Kerdja, Bénédicte Clarisse, Gwenaelle Boudier, François Cherifi, Mélanie Briand, Enora Dolivet, Alisson Johnson, Brice Dubois, Valentin Harter…
    Citation: BMC Cancer 2023 23:883
    Content type: Study Protocol Published on:

  11. Thyroid cancer (TC) is one of the most common endocrine malignancies, and its morbidity continues to rise. N6-methyladenosine (m6A) RNA methylation, an epigenetic modification, is an important regulator of gene e...

    Authors: Yihan Zhang, Ying Chen, Ruihua Chen, Hong Zhou, Yi Lin, Bingxin Li, Huaidong Song, Guoqiang Zhou, Mei Dong and Huanbai Xu
    Citation: BMC Cancer 2023 23:882
    Content type: Research Published on:

  12. Breast cancer is the commonest cancer among women in India, yet the uptake of early detection programs is poor. This leads to late presentation, advanced stage at the time of diagnosis, and high mortality. Poo...

    Authors: Riya Sawhney, Priyansh Nathani, Priti Patil, Prashant Bhandarkar, Deepa Kizhakke Veetil, Jubina Balan Venghateri, Nobhojit Roy and Anita Gadgil
    Citation: BMC Cancer 2023 23:881
    Content type: Research Published on:

  13. Guidelines recommend total thyroidectomy (TT) to facilitate radioactive ablation and serological follow-up for intermediate- to high-risk papillary thyroid carcinoma (PTC). However, the association between sur...

    Authors: Siyuan Xu, Hui Huang, Huilei Dong, Xiaolei Wang, Zhengang Xu, Shaoyan Liu and Jie Liu
    Citation: BMC Cancer 2023 23:880
    Content type: Research Published on:

  14. The epithelial-mesenchymal transition (EMT) plays an indispensable role in the development and progression of Endometrial cancer (EC). Nevertheless, little evidence is reported to uncover the functionality and...

    Authors: Yonghui Yu, Yiwen Zhang, Zhi Li, Yongshun Dong, Hongmei Huang, Binyao Yang, Eryong Zhao, Yongxiu Chen, Lei Yang, Jiachun Lu and Fuman Qiu
    Citation: BMC Cancer 2023 23:879
    Content type: Research Published on:

  15. Colorectal cancer (CRC) is one of the malignant tumors with the highest morbidity and mortality and poor prognosis. The mammalian gene family of Cab45/reticulocalbin/ERC-45/calumenin (CREC) consists of RCN1, R...

    Authors: Junya Ning, Min Liu, Jing Shen, Deping Wang, Lijuan Gao, Huiyu Li and Jimin Cao
    Citation: BMC Cancer 2023 23:878
    Content type: Research Published on:

  16. Real-world data on treatment patterns/outcomes for metastatic pancreatic cancer (mPAC) are limited. This study aims to assess real-world treatment patterns, survival outcomes, and prognostic/predictive factors...

    Authors: Julien Taieb, Thomas Seufferlein, Michele Reni, Daniel H. Palmer, John A. Bridgewater, Antonio Cubillo, Gerald W. Prager, Alice Vermeire, Fabienne Hédouin-Biville, Zhaoyang Teng and Teresa Macarulla
    Citation: BMC Cancer 2023 23:877
    Content type: Research Published on:

  17. Pancreatic cancer poses a serious medical problem worldwide. Countries in the Western Pacific Region are facing public health challenges from cancer. This study assesses the time trends of pancreatic cancer mo...

    Authors: Wenkai Jiang, Caifei Xiang, Yan Du, Xiao Li, Xin Li and Wence Zhou
    Citation: BMC Cancer 2023 23:876
    Content type: Database Published on:

  18. Vietnam and Saudi Arabia have high disease burden of primary hepatocellular carcinoma (HCC). Early detection in asymptomatic patients at risk for HCC is a strategy to improve survival outcomes in HCC managemen...

    Authors: Thai Ngoc Truong, Trang Ngoc Doan Pham, Long Bao Hoang, Van Thi Nguyen, Hang Viet Dao, Diem Vu Bich Dao, Saleh Alessy, Hien Ba Pham, Thuy Thi Thu Pham, Linh Duc Duy Nguyen, Khue Nguyen, Faisal Abaalkhail, Mohammed Manal, Mohammad Mawardi, May AlZahrani, Khalid Alswat…
    Citation: BMC Cancer 2023 23:875
    Content type: Study protocol Published on:

  19. Telomeres are repetitive DNA sequences located at the ends of chromosomes, playing a vital role in maintaining chromosomal integrity and stability. Dysregulation of telomeres has been implicated in the develop...

    Authors: Gh. Rasool Bhat, Rajeshwer Singh Jamwal, Itty Sethi, Amrita Bhat, Ruchi Shah, Sonali Verma, Minerva Sharma, Hana Q. Sadida, Sara K. Al-Marzooqi, Tariq Masoodi, Sameer Mirza, Mohammad Haris, Muzafar A. Macha, Ammira S. Alshabeeb Akil, Ajaz A. Bhat and Rakesh Kumar
    Citation: BMC Cancer 2023 23:874
    Content type: Research Published on:

  20. The aim of the present study was to assess the efficacy and safety of transarterial chemoembolization (TACE) combined with atezolizumab and bevacizumab (hereafter, TACE-Atez/Bev) in the treatment of advanced h...

    Authors: Fei Cao, Changsheng Shi, Guofu Zhang, Jun Luo, Jiaping Zheng and Weiyuan Hao
    Citation: BMC Cancer 2023 23:873
    Content type: Research Published on:

  21. Lung cancer is a major global threat to public health for which a novel predictive nomogram is urgently needed. Non-small cell lung cancer (NSCLC) which accounts for the main port of lung cancer cases is attra...

    Authors: Zufang Liao, Rongjiong Zheng, Ni Li and Guofeng Shao
    Citation: BMC Cancer 2023 23:872
    Content type: Research Published on:

  22. We aimed to analyze the benefit of adjuvant chemotherapy in high-risk stage II colon cancer patients and the impact of high-risk factors on the prognostic effect of adjuvant chemotherapy.

    Authors: Kexuan Li, Fuqiang Zhao, Yuchen Guo, Qingbin Wu, Shuangling Luo, Junling Zhang, Heli Li, Shidong Hu, Bin Wu, Guole Lin, Huizhong Qiu, Beizhan Niu, Xiyu Sun, Lai Xu, Junyang Lu, Xiaohui Du…
    Citation: BMC Cancer 2023 23:797
    Content type: Research Published on:

  23. While the treatment guidelines have been established for pure urothelial carcinoma (pUC), patients with variant type urothelial carcinoma (vUC) face limited effective treatment options. The effectiveness of im...

    Authors: Tsung-Han Tsai, Po-Jung Su, Shih-Yu Huang, Ming-Chun Kuo, Chang-Ting Lin, Chia-Che Wu, Hao-Lun Luo, Chien-Hsu Chen, Chih-Chi Chou, Ting-Ting Liu, Chun-Chieh Huang, Kai-Lung Tsai and Yu-Li Su
    Citation: BMC Cancer 2023 23:871
    Content type: Research Published on:

  24. Two thirds of patients with germ-cell cancer (GCC) present as clinical stage I (CSI). Following orchiectomy, active surveillance (AS) has become their standard management. However, 15–50% of patients eventuall...

    Authors: Philip Speicher, Christian D. Fankhauser, Anja Lorch, Davide Ardizzone, Simon Helnwein, Dennis Hoch, Thomas Hermanns, Jörg Beyer and Dilara Akhoundova
    Citation: BMC Cancer 2023 23:870
    Content type: Research Published on:

  26. Novel and effective immunotherapies are required for refractory or recurrent sarcomas. Transforming growth factor-beta (TGF-β) is a diverse regulatory and fibrogenic protein expressed in multiple sarcoma tumo...

    Authors: Lu Xie, Xin Liang, Jie Xu, Xin Sun, Kuisheng Liu, Kunkun Sun, Yuan Li, Xiaodong Tang, Xianan Li, Xing Zhan, Xiaohui Niu and Wei Guo
    Citation: BMC Cancer 2023 23:868
    Content type: Research Published on:

  27. The aim of this study is to explore the general impact of COVID-19 on the access and use of BC services and support and overall well-being in women living with a diagnosis of breast cancer (BC) and to investig...

    Authors: Charlotte Myers, Catherine Waldron, Kathleen Bennett and Caitriona Cahir
    Citation: BMC Cancer 2023 23:867
    Content type: Research Published on:

  28. Cardiotoxicity is among the most important adverse effects of childhood cancer treatment. Anthracyclines, mitoxantrone and radiotherapy involving the heart are its main causes. Subclinical cardiac dysfunction ...

    Authors: Theodorus W. Kouwenberg, Elvira C. van Dalen, Elizabeth A. M. Feijen, Stejara A. Netea, Melissa Bolier, Martijn G. Slieker, Firdaus A. A. Mohamed Hoesein, Leontien C. M. Kremer, Heynric B. Grotenhuis and Annelies M. C. Mavinkurve-Groothuis
    Citation: BMC Cancer 2023 23:866
    Content type: Research Published on:

  29. Radiotherapy (RT) following breast-conserving surgery (BCS) is mainly used to decrease the rate of ipsilateral breast tumor recurrence (IBTR) in women with breast ductal carcinoma in situ (DCIS). Recent studie...

    Authors: Sung-Hsin Kuo, Ling-Ming Tseng, Shou-Tung Chen, Yasuaki Sagara, Yuan-Ching Chang, Hsien-Tang Yeh, Yao-Lung Kuo, Chih-Chiang Hung, Tzu-Pin Lu, Yi-Hsuan Lee, Masakazu Toi and Chiun-Sheng Huang
    Citation: BMC Cancer 2023 23:865
    Content type: Study Protocol Published on:

  30. Clear cell renal cell carcinoma (CCRCC) is a common tumor of the urological system for which surgery is the preferred treatment, but there is a lack of therapeutic options after surgery. This study aims to exp...

    Authors: Jun Zheng, Weili Zhang and Junyong Zhang
    Citation: BMC Cancer 2023 23:864
    Content type: Research Published on:

  31. Pain is a common, debilitating, and feared symptom, including among cancer survivors. However, large-scale population-based evidence on pain and its impact in cancer survivors is limited. We quantified the pre...

    Authors: Grace Joshy, Saman Khalatbari-Soltani, Kay Soga, Phyllis Butow, Rebekah Laidsaar-Powell, Bogda Koczwara, Nicole M. Rankin, Sinan Brown, Marianne Weber, Carolyn Mazariego, Paul Grogan, John Stubbs, Stefan Thottunkal, Karen Canfell, Fiona M. Blyth and Emily Banks
    Citation: BMC Cancer 2023 23:774
    Content type: Research article Published on:

  32. Increasing women’s health literacy is the key to preventing cervical cancer, and various tools have been developed to assess women’s cancer health literacy. However, many of these tools come from other countri...

    Authors: Chanchan He, Chenyang Pei and Jing Ma
    Citation: BMC Cancer 2023 23:863
    Content type: Research Published on:

  33. Cancer cells are characterized by changes in cell cytoskeletal architecture and stiffness. Despite advances in understanding the molecular mechanisms of musculoskeletal cancers, the corresponding cellular mech...

    Authors: Cyril Daniel, Frank Traub, Saskia Sachsenmaier, Rosa Riester, Moritz Mederake, Christian Konrads and Marina Danalache
    Citation: BMC Cancer 2023 23:862
    Content type: Research Published on:

  34. Recent achievements in cancer therapy are the use of alternating electrical fields at intermediate frequencies (100–300 kHz) and low intensities (1–3 V/cm), which specifically target cell proliferation while a...

    Authors: Elham Homami, Bahram Goliaei, Seyed Peyman Shariatpanahi and Zahra Habibi-Kelishomi
    Citation: BMC Cancer 2023 23:861
    Content type: Research Published on:

  35. Rectal cancer is one of the most common malignant tumors and has a high incidence rate and fatality rate. Accurate preoperative T staging of rectal cancer is critical for the selection of appropriate rectal ca...

    Authors: Qin Xia, Wei Cheng, Jie Bi, An-Ping Ren, Xiao Chen and Tao Li
    Citation: BMC Cancer 2023 23:860
    Content type: Research Published on:

  37. Downstaging of hepatocellular carcinoma (HCC) makes it possible for patients beyond the criteria to have the chance of liver transplantation (LT) and improved outcomes. Thus, a procedure to predict the prognos...

    Authors: Si-Yuan Wang, Kai Sun, Shuo Jin, Kai-Yu Wang, Nan Jiang, Si-Qiao Shan, Qian Lu, Guo-Yue Lv and Jia-Hong Dong
    Citation: BMC Cancer 2023 23:858
    Content type: Research Published on:

  38. The development of drug resistance and high mortality rates are the major problems observed in non-small cell lung cancer (NSCLC). Biomarkers indicating and predicting disease development towards these unfavor...

    Authors: Julija Simiene, Daiva Dabkeviciene, Diana Stanciute, Rimvile Prokarenkaite, Valerija Jablonskiene, Renatas Askinis, Kamile Normantaite, Saulius Cicenas and Kestutis Suziedelis
    Citation: BMC Cancer 2023 23:857
    Content type: Research Published on:

  39. Studies investigating the prevalence of pancreatic cancer have revealed a heightened risk of 1.5 to 2.0 times among individuals with long-standing type 2 diabetes mellitus.

    Authors: Fakhrddine Amri, Chifaa Belkhayat, Asmae yeznasni, Hajar Koulali, Rachid Jabi, Abdelkrim Zazour, Naima Abda, Mohammed Bouziane, Zahi Ismaili and Ghizlane Kharrasse
    Citation: BMC Cancer 2023 23:856
    Content type: Research Published on:

  40. Comprehensive insight in the longitudinal development of health-related quality of life (HRQOL) after childhood cancer diagnosis could improve quality of care. Thus, we aimed to study the course and biopsychos...

    Authors: Marloes van Gorp, Elin Irestorm, Jos W. R. Twisk, Natasja Dors, Annelies Mavinkurve-Groothuis, Antoinette Y. N. Schouten van Meeteren, Judith de Bont, Esther M. M. van den Bergh, Wietske van de Peppel van der Meer, Laura R. Beek, Femke K. Aarsen, Nienke Streefkerk, Raphaele R. L. van Litsenburg and Martha A. Grootenhuis
    Citation: BMC Cancer 2023 23:855
    Content type: Research Published on:

  41. Dysbiosis of gut microbiota has been linked to numerous diseases, including cancer. The unique role of gut microbiota in urological tumors is gaining prominence. However, it is still controversial whether the ...

    Authors: Wang Mingdong, Gao Xiang, Quan Yongjun, Wang Mingshuai and Ping Hao
    Citation: BMC Cancer 2023 23:854
    Content type: Research Published on:

  42. Cervical cancer is a common gynecological malignancy. Gene microarray found that TCP11 gene was highly expressed in cervical cancer. However, the effect of TCP11 gene on the proliferation, apoptosis and migration...

    Authors: Fang Wang, Shuyan Song, Bingxuan Guo, Yangyang Li, Huijuan Wang, Shaowei Fu, Luyue Wang, Xiangyi Zhe, Hongtao Li, Dongmei Li, Renfu Shao and Zemin Pan
    Citation: BMC Cancer 2023 23:853
    Content type: Research Published on:

  43. Program sensitivity is a key quality indicator for mammography screening programs (MSP). Estimating program sensitivity usually requires a linkage of screening and cancer registry data. For the German MSP, suc...

    Authors: Franziska Heinze, Jonas Czwikla, Miriam Heinig, Ingo Langner and Ulrike Haug
    Citation: BMC Cancer 2023 23:852
    Content type: Research Published on:

  45. Radical resection is still the most cost-effectiveness curative strategy for intrahepatic cholangiocarcinoma (ICC), but it remains controversial on the survival benefit of anatomic resection (AR). In this stud...

    Authors: Qiao Ke, Lei Wang, Ziguo Lin, Hongzhi Liu, Jianying Lou, Shuguo Zheng, Xinyu Bi, Jianming Wang, Wei Guo, Fuyu Li, Jian Wang, Yamin Zheng, Jingdong Li, Shi Cheng, Weiping Zhou, Jingfeng Liu…
    Citation: BMC Cancer 2023 23:850
    Content type: Research Published on:

  46. Epilepsy is a major symptom in patients with glioma. Levetiracetam (LEV) is recognized as a first-line treatment for glioma-related epilepsy. Increasing the LEV dose is allowed into patients with seizure occur...

    Authors: Etsuko Yamamoto Hattori, Yoshiki Arakawa, Yohei Mineharu, Keiko Furukawa, Yukinori Terada, Yukihiro Yamao, Masahiro Tanji, Takayuki Kikuchi and Susumu Miyamoto
    Citation: BMC Cancer 2023 23:849
    Content type: Research Published on:

  47. We aimed to develop machine learning models for prediction of molecular subgroups (low-risk group and intermediate/high-risk group) and molecular marker (KIAA1549-BRAF fusion) of pediatric low-grade gliomas (PLGG...

    Authors: Zhen Liu, Xuanke Hong, Linglong Wang, Zeyu Ma, Fangzhan Guan, Weiwei Wang, Yuning Qiu, Xueping Zhang, Wenchao Duan, Minkai Wang, Chen Sun, Yuanshen Zhao, Jingxian Duan, Qiuchang Sun, Lin Liu, Lei Ding…
    Citation: BMC Cancer 2023 23:848
    Content type: Research Published on:

  48. The patient population with stage III non-small-cell lung cancer (NSCLC) is heterogeneous, with varying staging characteristics and diverse treatment options. Despite the potential practice-changing implicatio...

    Authors: Chieh-Lung Chen, Sing-Ting Wang, Wei-Chih Liao, Chia-Hung Chen, Chih-Yen Tu, Te-Chun Hsia, Wen-Chien Cheng and Hung-Jen Chen
    Citation: BMC Cancer 2023 23:847
    Content type: Research Published on:

  49. Gliomas are the most common malignant primary brain tumors in adults with poor prognoses. The purpose of this study is to explore CACNG3 as a prognostic factor that is closely related to the progression and su...

    Authors: Enfang Shan, Yi-nan Cao, Yang Zhang, Wen Chen, Xurui Ren, Shanjie Zhu, Xueru Xi, Shuai Mu, Mian Ma, Tongle Zhi and Xianwen Li
    Citation: BMC Cancer 2023 23:846
    Content type: Research Published on:

  50. Cervical cancer is the fourth most common cancer among women worldwide. Genome-wide association studies have revealed multiple susceptible genes and their polymorphisms for cervical cancer risk. Therefore, we ...

    Authors: Manning Zhu, Xiaoying Li, Yanan Feng, Tianshuang Jia, Songxue Li, Liping Gong, Shuang Dong, Xianchao Kong and Litao Sun
    Citation: BMC Cancer 2023 23:845
    Content type: Research Published on:

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