Lu HY, Wang XJ, Mao WM: Targeted therapies in small cell lung cancer. Oncol Lett. 2013, 5 (1): 3-11.
CAS
PubMed
Google Scholar
Shuman Moss LA, Jensen-Taubman S, Stetler-Stevenson WG: Matrix metalloproteinases: changing roles in tumor progression and metastasis. Am J Pathol. 2012, 181 (6): 1895-1899. 10.1016/j.ajpath.2012.08.044.
Article
PubMed
PubMed Central
Google Scholar
Shah SA, Spinale FG, Ikonomidis JS, Stroud RE, Chang EI, Reed CE: Differential matrix metalloproteinase levels in adenocarcinoma and squamous cell carcinoma of the lung. J Thorac Cardiovasc Surg. 2010, 139 (4): 984-990. 10.1016/j.jtcvs.2009.12.016. discussion 990
Article
CAS
PubMed
PubMed Central
Google Scholar
Yamamura T, Nakanishi K, Hiroi S, Kumaki F, Sato H, Aida S, Kawai T: Expression of membrane-type-1-matrix metalloproteinase and metalloproteinase-2 in nonsmall cell lung carcinomas. Lung Cancer. 2002, 35 (3): 249-255. 10.1016/S0169-5002(01)00431-7.
Article
PubMed
Google Scholar
Leinonen T, Pirinen R, Bohm J, Johansson R, Ropponen K, Kosma VM: Expression of matrix metalloproteinases 7 and 9 in non-small cell lung cancer. Relation to clinicopathological factors, beta-catenin and prognosis. Lung Cancer. 2006, 51 (3): 313-321. 10.1016/j.lungcan.2005.11.002.
Article
PubMed
Google Scholar
Stenvold H, Donnem T, Andersen S, Al-Saad S, Al-Shibli K, Busund LT, Bremnes RM: Overexpression of matrix metalloproteinase-7 and −9 in NSCLC tumor and stromal cells: correlation with a favorable clinical outcome. Lung Cancer. 2012, 75 (2): 235-241. 10.1016/j.lungcan.2011.06.010.
Article
PubMed
Google Scholar
Rintoul RC, Sethi T: The role of extracellular matrix in small-cell lung cancer. Lancet Oncol. 2001, 2 (7): 437-442. 10.1016/S1470-2045(00)00421-6.
Article
CAS
PubMed
Google Scholar
Michael M, Babic B, Khokha R, Tsao M, Ho J, Pintilie M, Leco K, Chamberlain D, Shepherd FA: Expression and prognostic significance of metalloproteinases and their tissue inhibitors in patients with small-cell lung cancer. J Clin Oncol. 1999, 17 (6): 1802-1808.
CAS
PubMed
Google Scholar
Johnson JL, Pillai S, Pernazza D, Sebti SM, Lawrence NJ, Chellappan SP: Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease. Cancer Res. 2012, 72 (2): 516-526. 10.1158/0008-5472.CAN-11-2647.
Article
CAS
PubMed
Google Scholar
Gottschall PE, Deb S: Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons. Neuroimmunomodulation. 1996, 3 (2–3): 69-75.
Article
CAS
PubMed
Google Scholar
Law JA, Jacobsen SE: Establishing, maintaining and modifying DNA methylation patterns in plants and animals. Nat Rev Genet. 2010, 11 (3): 204-220. 10.1038/nrg2719.
Article
CAS
PubMed
PubMed Central
Google Scholar
Labrie M, St-Pierre Y: Epigenetic regulation of mmp-9 gene expression. Cell Mol Life Sci. 2013, 70 (17): 3109-3124. 10.1007/s00018-012-1214-z.
Article
CAS
PubMed
Google Scholar
Vincenti MP, Brinckerhoff CE: Signal transduction and cell-type specific regulation of matrix metalloproteinase gene expression: can MMPs be good for you?. J Cell Physiol. 2007, 213 (2): 355-364. 10.1002/jcp.21208.
Article
CAS
PubMed
Google Scholar
Chetty C, Rao JS, Lakka SS: Matrix metalloproteinase pharmacogenomics in non-small-cell lung carcinoma. Pharmacogenomics. 2011, 12 (4): 535-546. 10.2217/pgs.10.207.
Article
CAS
PubMed
Google Scholar
Ji W, Zhang W, Xiao W: E2F-1 directly regulates thrombospondin 1 expression. PLoS One. 2010, 5 (10): e13442-10.1371/journal.pone.0013442.
Article
PubMed
PubMed Central
Google Scholar
Minato Y, Tashiro E, Kanai M, Nihei Y, Kodama Y, Imoto M: Transcriptional regulation of a new variant of human platelet-derived growth factor receptor alpha transcript by E2F-1. Gene. 2007, 403 (1–2): 89-97.
Article
CAS
PubMed
Google Scholar
Pillai S, Kovacs M, Chellappan S: Regulation of vascular endothelial growth factor receptors by Rb and E2F1: role of acetylation. Cancer Res. 2010, 70 (12): 4931-4940. 10.1158/0008-5472.CAN-10-0501.
Article
CAS
PubMed
PubMed Central
Google Scholar
Banerjee D, Gorlick R, Liefshitz A, Danenberg K, Danenberg PC, Danenberg PV, Klimstra D, Jhanwar S, Cordon-Cardo C, Fong Y, Kemeny N, Bertino JR: Levels of E2F-1 expression are higher in lung metastasis of colon cancer as compared with hepatic metastasis and correlate with levels of thymidylate synthase. Cancer Res. 2000, 60 (9): 2365-2367.
CAS
PubMed
Google Scholar
Law SF, Estojak J, Wang B, Mysliwiec T, Kruh G, Golemis EA: Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae. Mol Cell Biol. 1996, 16 (7): 3327-3337.
Article
CAS
PubMed
PubMed Central
Google Scholar
Li J, Hu SX, Perng GS, Zhou Y, Xu K, Zhang C, Seigne J, Benedict WF, Xu HJ: Expression of the retinoblastoma (RB) tumor suppressor gene inhibits tumor cell invasion in vitro. Oncogene. 1996, 13 (11): 2379-2386.
CAS
PubMed
Google Scholar
Eymin B, Gazzeri S, Brambilla C, Brambilla E: Distinct pattern of E2F1 expression in human lung tumours: E2F1 is upregulated in small cell lung carcinoma. Oncogene. 2001, 20 (14): 1678-1687. 10.1038/sj.onc.1204242.
Article
CAS
PubMed
Google Scholar
Hu Z, Gu Y, Han B, Zhang J, Li Z, Tian K, Young CY, Yuan H: Knockdown of AGR2 induces cellular senescence in prostate cancer cells. Carcinogenesis. 2012, 33 (6): 1178-1186. 10.1093/carcin/bgs141.
Article
CAS
PubMed
Google Scholar
Shao S, Li Z, Gao W, Yu G, Liu D, Pan F: ADAM-12 as a Diagnostic Marker for the Proliferation, Migration and Invasion in Patients with Small Cell Lung Cancer. PLoS One. 2014, 9 (1): e85936-10.1371/journal.pone.0085936.
Article
PubMed
PubMed Central
Google Scholar
Xi G, Hu X, Wu B, Jiang H, Young CY, Pang Y, Yuan H: Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells. Cancer Lett. 2011, 307 (2): 141-148. 10.1016/j.canlet.2011.03.026.
Article
CAS
PubMed
Google Scholar
Liu YQ, Hu XY, Lu T, Cheng YN, Young CY, Yuan HQ, Lou HX: Retigeric acid B exhibits antitumor activity through suppression of nuclear factor-kappaB signaling in prostate cancer cells in vitro and in vivo. PLoS One. 2012, 7 (5): e38000-10.1371/journal.pone.0038000.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zacharatos P, Kotsinas A, Evangelou K, Karakaidos P, Vassiliou LV, Rezaei N, Kyroudi A, Kittas C, Patsouris E, Papavassiliou AG, Gorgoulis VG: Distinct expression patterns of the transcription factor E2F-1 in relation to tumour growth parameters in common human carcinomas. J Pathol. 2004, 203 (3): 744-753. 10.1002/path.1582.
Article
CAS
PubMed
Google Scholar
Hung JJ, Hsueh CT, Chen KH, Hsu WH, Wu YC: Clinical significance of E2F1 protein expression in non-small cell lung cancer. Exp Hematol Oncol. 2012, 1 (1): 18-10.1186/2162-3619-1-18.
Article
CAS
PubMed
PubMed Central
Google Scholar
Huang CL, Liu D, Nakano J, Yokomise H, Ueno M, Kadota K, Wada H: E2F1 overexpression correlates with thymidylate synthase and survivin gene expressions and tumor proliferation in non small-cell lung cancer. Clin Cancer Res. 2007, 13 (23): 6938-6946. 10.1158/1078-0432.CCR-07-1539.
Article
CAS
PubMed
Google Scholar
Kuhn H, Liebers U, Gessner C, Schumacher A, Witt C, Schauer J, Kovesdi I, Wolff G: Adenovirus-mediated E2F-1 gene transfer in nonsmall-cell lung cancer induces cell growth arrest and apoptosis. Eur Respir J. 2002, 20 (3): 703-709. 10.1183/09031936.02.00294502.
Article
CAS
PubMed
Google Scholar
Gorgoulis VG, Zacharatos P, Mariatos G, Kotsinas A, Bouda M, Kletsas D, Asimacopoulos PJ, Agnantis N, Kittas C, Papavassiliou AG: Transcription factor E2F-1 acts as a growth-promoting factor and is associated with adverse prognosis in non-small cell lung carcinomas. J Pathol. 2002, 198 (2): 142-156. 10.1002/path.1121.
Article
CAS
PubMed
Google Scholar
DeMuth JP, Jackson CM, Weaver DA, Crawford EL, Durzinsky DS, Durham SJ, Zaher A, Phillips ER, Khuder SA, Willey JC: The gene expression index c-myc x E2F-1/p21 is highly predictive of malignant phenotype in human bronchial epithelial cells. Am J Respir Cell Mol Biol. 1998, 19 (1): 18-24. 10.1165/ajrcmb.19.1.3077.
Article
CAS
PubMed
Google Scholar
Bogos K, Renyi-Vamos F, Dobos J, Kenessey I, Tovari J, Timar J, Strausz J, Ostoros G, Klepetko W, Ankersmit HJ, Lang G, Hoda MA, Nierlich P, Dome B: High VEGFR-3-positive circulating lymphatic/vascular endothelial progenitor cell level is associated with poor prognosis in human small cell lung cancer. Clin Cancer Res. 2009, 15 (5): 1741-1746. 10.1158/1078-0432.CCR-08-1372.
Article
CAS
PubMed
Google Scholar
Mengshol JA, Vincenti MP, Brinckerhoff CE: IL-1 induces collagenase-3 (MMP-13) promoter activity in stably transfected chondrocytic cells: requirement for Runx-2 and activation by p38 MAPK and JNK pathways. Nucleic Acids Res. 2001, 29 (21): 4361-4372. 10.1093/nar/29.21.4361.
Article
CAS
PubMed
PubMed Central
Google Scholar
Murthy S, Ryan AJ, Carter AB: SP-1 regulation of MMP-9 expression requires Ser586 in the PEST domain. Biochem J. 2012, 445 (2): 229-236.
Article
CAS
PubMed
PubMed Central
Google Scholar
Guan H, Cai J, Zhang N, Wu J, Yuan J, Li J, Li M: Sp1 is upregulated in human glioma, promotes MMP-2-mediated cell invasion and predicts poor clinical outcome. Int J Cancer. 2012, 130 (3): 593-601. 10.1002/ijc.26049.
Article
CAS
PubMed
Google Scholar
Tang X, Liu D, Shishodia S, Ozburn N, Behrens C, Lee JJ, Hong WK, Aggarwal BB, Wistuba II: Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung cancer and preneoplastic lesions. Cancer. 2006, 107 (11): 2637-2646. 10.1002/cncr.22315.
Article
CAS
PubMed
Google Scholar
Zhang SY, Liu SC, Johnson DG, Klein-Szanto AJ: E2F-1 gene transfer enhances invasiveness of human head and neck carcinoma cell lines. Cancer Res. 2000, 60 (21): 5972-5976.
CAS
PubMed
Google Scholar
Lin SY, Black AR, Kostic D, Pajovic S, Hoover CN, Azizkhan JC: Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction. Mol Cell Biol. 1996, 16 (4): 1668-1675.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kramps C, Strieder V, Sapetschnig A, Suske G, Lutz W: E2F and Sp1/Sp3 Synergize but are not sufficient to activate the MYCN gene in neuroblastomas. J Biol Chem. 2004, 279 (7): 5110-5117.
Article
CAS
PubMed
Google Scholar
Rotheneder H, Geymayer S, Haidweger E: Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter. J Mol Biol. 1999, 293 (5): 1005-1015. 10.1006/jmbi.1999.3213.
Article
CAS
PubMed
Google Scholar
Wong CF, Barnes LM, Dahler AL, Smith L, Popa C, Serewko-Auret MM, Saunders NA: E2F suppression and Sp1 overexpression are sufficient to induce the differentiation-specific marker, transglutaminase type 1, in a squamous cell carcinoma cell line. Oncogene. 2005, 24 (21): 3525-3534. 10.1038/sj.onc.1208372.
Article
CAS
PubMed
Google Scholar
Chen M, Capps C, Willerson JT, Zoldhelyi P: E2F-1 regulates nuclear factor-kappaB activity and cell adhesion: potential antiinflammatory activity of the transcription factor E2F-1. Circulation. 2002, 106 (21): 2707-2713. 10.1161/01.CIR.0000038706.30661.86.
Article
CAS
PubMed
Google Scholar
Shaw J, Yurkova N, Zhang T, Gang H, Aguilar F, Weidman D, Scramstad C, Weisman H, Kirshenbaum LA: Antagonism of E2F-1 regulated Bnip3 transcription by NF-kappaB is essential for basal cell survival. Proc Natl Acad Sci U S A. 2008, 105 (52): 20734-20739. 10.1073/pnas.0807735105.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gang H, Dhingra R, Wang Y, Mughal W, Gordon JW, Kirshenbaum LA: Epigenetic regulation of E2F-1-dependent Bnip3 transcription and cell death by nuclear factor-kappaB and histone deacetylase-1. Pediatr Cardiol. 2011, 32 (3): 263-266. 10.1007/s00246-011-9893-z.
Article
PubMed
Google Scholar