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Table 5 The statistical difference between E2F lower, moderate and higher and clinicopathological variables

From: Differential regulation of MMPs by E2F1, Sp1 and NF-kappa B controls the small cell lung cancer invasive phenotype

Variables

E2F1 expression

Spearman

χ2 test

  

−/+

++

+++

R

P

χ2

P

Age

<55

7

11

19

0.103

0.334

1.069

0.586

≥55

8

12

33

Gender

Male

9

20

39

0.038

0.725

3.193

0.166

Female

6

3

13

Smoking

Non-smoker

4

3

14

0.068

0.518

1.829

0.411

Smoker

11

20

38

Tumor size

<4 cm

9

12

35

0.105

0.325

1.592

0.451

≥4 cm

6

11

17

Clinical stage

LD*

13

10

7

0.552

< 0.01

29.506

<0.01

ED*

2

13

45

  1. −/+ represents E2F1 weak expression, ++ represents E2F1 moderate expression, +++ represents E2F1 higher expression, LD* represents limited disease and ED* represents extensive disease.