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  1. Differentiation of glioma and solitary brain metastasis (SBM), which requires biopsy or multi-disciplinary diagnosis, remains sophisticated clinically. Histogram analysis of MR diffusion or molecular imaging h...

    Authors: Yifei Su, Rui Cheng, Jinxia Guo, Miaoqi Zhang, Junhao Wang, Hongming Ji, Chunhong Wang, Liangliang Hao, Yexin He and Cheng Xu
    Citation: BMC Cancer 2024 24:805
    Content type: Research Published on:

  2. Over the last decades, the therapeutic armamentarium of metastatic renal cell carcinoma (mRCC) has been revolutionized by the advent of tyrosin-kinase inhibitors (TKI), immune-checkpoint inhibitors (ICI), and ...

    Authors: Mimma Rizzo, Gaetano Pezzicoli, Valentina Tibollo, Andrea Premoli and Silvana Quaglini
    Citation: BMC Cancer 2024 24:804
    Content type: Research Published on:

  3. Trabectedin in combination with pegylated liposomal doxorubicin (PLD) is approved for the treatment of patients with platinum-sensitive relapsed ovarian cancer. Nevertheless, there is currently limited informa...

    Authors: María Jesús Rubio, Aránzazu Manzano, Luis Miguel de Sande, Purificación Estévez-García, María del Mar Gordon, Diego Soto de Prado, Blanca Hernando Fernández de Aranguiz, Eva M. Guerra-Alia, Anna Carbó-Bagué, Ignacio Romero, Miguel Corbellas, Alba González-Haba, Carlos E. Robles-Barraza, Jerónimo Martínez-García and Antonio González-Martín
    Citation: BMC Cancer 2024 24:803
    Content type: Research Published on:

  4. The period between cancer diagnosis and surgery presents an opportunity for trials to assess the feasibility of behaviour change interventions. However, this can be a worrying time for patients and may hinder ...

    Authors: Amelia Talbot, Susan A Jebb, Claire Foster, Alba X Realpe, Pete Wheatstone, Simon Buczacki and Dimitrios A Koutoukidis
    Citation: BMC Cancer 2024 24:802
    Content type: Research Published on:

  5. Lung cancer still ranks first in the mortality rate of cancer. Uric acid is a product of purine metabolism in humans. Its presence in the serum is controversial; some say that its high levels have a protective...

    Authors: Ping Lin, Linxiang Zhang, Xiaohui Tang and Jihuang Wang
    Citation: BMC Cancer 2024 24:801
    Content type: Research Published on:

  6. Drug resistance remains a significant challenge in the treatment of pancreatic cancer. The development of drug-resistant cell lines is crucial to understanding the underlying mechanisms of resistance and devel...

    Authors: Cheng Yu, Yuanhui Su, Xin Miao, Changpeng Chai, Huan Tang, Lu Li, Jianfeng Yi, Zhenzhen Ye, Hui Zhang, Zhao Hu, Luyang Chen, Ning Li, Hao Xu and Wence Zhou
    Citation: BMC Cancer 2024 24:800
    Content type: Research Published on:

  7. Craniopharyngioma (CP) is a rare malformational tumor characterized by high rates of recurrence and morbid obesity. However, the role of inflammatory mediators in obesity and the prognosis of patients with CP ...

    Authors: Youchao Xiao, Wentao Wu, Fangzheng Liu, Yanfei Jia, Lu Jin, Ning Qiao, Kefan Cai, Siming Ru, Lei Cao and Songbai Gui
    Citation: BMC Cancer 2024 24:799
    Content type: Research Published on:

  8. Many cancer survivors experience cancer-related cognitive impairment (CRCI), often with significant negative consequences across various life domains. Emerging evidence suggests that allowing additional time t...

    Authors: Darren Haywood, Frank D. Baughman, Evan Dauer, Jennifer Haywood, Susan Rossell and Nicolas H. Hart
    Citation: BMC Cancer 2024 24:798
    Content type: Research Published on:

  9. Patients with recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) have proven benefit from anti-programmed cell death 1 (anti-PD-1) monotherapy. Here, we retrospectively analyze the association of plasma...

    Authors: Shaoyan Lin, Huaqiang Zhou, Gang Chen, Jinhui Xue, Qianwen Liu, Jianing Li, Yanhua Yang, Yuanyuan Zhao, Hua Bao, Yan Huang, Yuxiang Ma and Hongyun Zhao
    Citation: BMC Cancer 2024 24:797
    Content type: Research Published on:

  10. The incidence of Hodgkin's lymphoma (HL) in people living with HIV (PLWHA) and on HAART is approximately 20–30 times higher than in HIV-negative individuals. Most patients with HIV-HL present at an advanced st...

    Authors: Mercy M. Mbai, Emmanuel Mduma, Samuel Thuo, Eulade Rugengamanzi, Christina V. Malichewe and Emmanuel L. Lugina
    Citation: BMC Cancer 2024 24:796
    Content type: Research Published on:

  11. Oral Squamous Cell Carcinoma (OSCC) presents significant diagnostic challenges in its early and late stages. This study aims to utilize preoperative MRI and biochemical indicators of OSCC patients to predict t...

    Authors: Wen Li, Yang Li, Shiyu Gao, Nengwen Huang, Ikuho Kojima, Taro Kusama, Yanjing Ou, Masahiro Iikubo and Xuegang Niu
    Citation: BMC Cancer 2024 24:795
    Content type: Research Published on:

  12. Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal role in maintaining skin homeostasis. In cancer, KLK...

    Authors: Simon Kind, Carolina Palacios Castillo, Ria Schlichter, Natalia Gorbokon, Maximilian Lennartz, Lisa S. Hornsteiner, Sebastian Dwertmann Rico, Viktor Reiswich, Florian Viehweger, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Franziska Büscheck, Till S. Clauditz, Christoph Fraune, Andrea Hinsch…
    Citation: BMC Cancer 2024 24:794
    Content type: Research Published on:

  13. Accurate regulation of gene expression is crucial for normal development and function of cells. The prognostic significance and potential carcinogenic mechanisms of the related gene JARID2 in OSCC are not yet ...

    Authors: Yuxi Cheng, Zhengzheng Song, Jingyi Cheng and Zhangui Tang
    Citation: BMC Cancer 2024 24:793
    Content type: Research Published on:

  14. The in vivo functions of SerpinB2 in tumor cells and tumor-associated macrophages (TAMs) during breast cancer development and metastasis remain elusive. SerpinB2-deficient MMTV-PyMT mice (PyMTSB2−/−) were previou...

    Authors: Yin Ji Piao, Hoe Suk Kim, Hyelim Kim, Jun Shen and Woo Kyung Moon
    Citation: BMC Cancer 2024 24:792
    Content type: Research Published on:

  15. Early screening and detection of lung cancer is essential for the diagnosis and prognosis of the disease. In this paper, we investigated the feasibility of serum Raman spectroscopy for rapid lung cancer screen...

    Authors: Linfang Yan, Huiting Su, Jiafei Liu, Xiaozheng Wen, Huaichao Luo, Yu Yin and Xiaoqiang Guo
    Citation: BMC Cancer 2024 24:791
    Content type: Research Published on:

  16. Melanoma, a deadly form of skin cancer, has witnessed a notable increase in incidence over the past decades. Despite advancements in treatment, it remains a significant cause of cancer mortality. Understanding...

    Authors: Alexander J. Didier, Swamroop V. Nandwani, Dean Watkins, Alan M. Fahoury, Andrew Campbell, Daniel J. Craig, Divya Vijendra and Nancy Parquet
    Citation: BMC Cancer 2024 24:790
    Content type: Research Published on:

  17. MicroRNA-1 (miR-1) is a tumour suppressor that can inhibit cell proliferation and invasion in several cancer types. In addition, miR-1 was found to be associated with drug sensitivity. Circulating miRNAs have ...

    Authors: Jing Peng, Yanping Lin, Xiaonan Sheng, Chenwei Yuan, Yan Wang, Wenjin Yin, Liheng Zhou and Jinsong Lu
    Citation: BMC Cancer 2024 24:789
    Content type: Research Published on:

  18. Developing cancer in young adulthood is a non-normative life event and associated with adverse physical, social and psychological consequences. High psychological distress is common in AYA cancer patients incl...

    Authors: Hannah Brock, Sarah Dwinger, Corinna Bergelt, Annekathrin Sender, Kristina Geue, Anja Mehnert-Theuerkauf and Diana Richter
    Citation: BMC Cancer 2024 24:788
    Content type: Study Protocol Published on:

  19. Cancer is becoming a major health problem in Uganda. Cancer control requires accurate estimates of the cancer burden for planning and monitoring of the cancer control strategies. However, cancer estimates and ...

    Authors: Annet Nakaganda, Angela Spencer, Collins Mpamani, Cissy Nassolo, Sarah Nambooze, Henry Wabinga, Isla Gemmell, Andrew Jones, Jackson Orem and Arpana Verma
    Citation: BMC Cancer 2024 24:787
    Content type: Research Published on:

  20. In Morocco, much progress has been made in breast cancer treatment. However, there is limited information on survival outcomes of breast cancer patients according to their therapeutic management.

    Authors: Hind Mrabti, Catherine Sauvaget, Karima Bendahhou, Farida Selmouni, Richard Muwonge, Eric Lucas, Youssef Chami, Maria Bennani, Hassan Errihani, Abdellatif Benider, Rachid Bekkali and Partha Basu
    Citation: BMC Cancer 2024 24:786
    Content type: Research Published on:

  21. Merkel cell carcinoma (MCC) is a rare, aggressive, cutaneous tumour with high mortality and frequently delayed diagnosis. Clinically, it often manifests as a rapidly growing erythematous to purple nodule usual...

    Authors: Dimitra Koumaki, Georgios Evangelou, Alexander C. Katoulis, Zoe Apalla, Aimilios Lallas, Marios Papadakis, Stamatios Gregoriou, Elizabeth Lazaridou and Konstantinos Krasagakis
    Citation: BMC Cancer 2024 24:785
    Content type: Research Published on:

  22. Physical activity is associated with improved disease progression and cancer-specific survival in patients with prostate cancer (PCa). However, the mechanisms underlying these associations remain unclear, whil...

    Authors: Jin-Soo Kim, Dennis R. Taaffe, Daniel A. Galvão, Timothy D. Clay, Andrew D. Redfern, Elin S. Gray and Robert U. Newton
    Citation: BMC Cancer 2024 24:784
    Content type: Study Protocol Published on:

  23. The number of cancer survivors has increased in recent decades, and the majority of them suffer from sequelae of their disease and treatment. This study, which is part of the larger research project OPTILATER,...

    Authors: Christian Speckemeier, K Maus, A Bialobrzeski, B Jaspers, L Radbruch, S Hahn, J Wasem, V Grünwald, U Dirksen and A Neumann
    Citation: BMC Cancer 2024 24:783
    Content type: Study Protocol Published on:

  24. The cardiotoxicity related to 5-Fluorouracil (5-FU) in cancer patients has garnered widespread attention. The systemic immune-inflammation index (SII) has recently been identified as a novel predictive marker ...

    Authors: Xiaoqin Liu, Yan Wang, Wenling Wang, Hongming Dong, Gang Wang, Wanghua Chen, Juan Chen and Weiwei Chen
    Citation: BMC Cancer 2024 24:782
    Content type: Research Published on:

  27. To explore the correlation between effective dose to immune cells (EDIC) and vertebral bone marrow dose and hematologic toxicity (HT) for esophageal squamous cell carcinoma (ESCC) during neoadjuvant chemoradio...

    Authors: Meng Zhang, Zhenjiang Li and Yong Yin
    Citation: BMC Cancer 2024 24:779
    Content type: Research Published on:

  28. Metal-regulatory transcription factor 1 (MTF1), a conserved metal-binding transcription factor in eukaryotes, regulates the proliferation of cancer cells by activating downstream target genes and then particip...

    Authors: Yujing Cheng, Chan Zhang, Qi Li, Xin Yang, Wanlu Chen, KunHua He and Mingwei Chen
    Citation: BMC Cancer 2024 24:778
    Content type: Research Published on:

  29. Evaluation publications typically summarize the results of studies to demonstrate the effectiveness of an intervention, but little is shared concerning any changes implemented during the study. We present a pr...

    Authors: Samia Valeria Ozorio Dutra, Lauren Schwab, Jillian Coury, Ming Ji and Constance Visovsky
    Citation: BMC Cancer 2024 24:777
    Content type: Study Protocol Published on:

  30. Primary cervical cancer screening and treating precancerous lesions are effective ways to prevent cervical cancer. However, the coverage rates of human papillomavirus (HPV) vaccines and routine screening are l...

    Authors: Wen Yang, Xiangshu Jin, Liying Huang, Shufang Jiang, Jia Xu, Yurong Fu, Yaoyao Song, Xueyan Wang, Xueqing Wang, Zhiming Yang and Yuanguang Meng
    Citation: BMC Cancer 2024 24:776
    Content type: Research Published on:

  31. Lung cancer (LC), characterized by high incidence and mortality rates, presents a significant challenge in oncology. Despite advancements in treatments, early detection remains crucial for improving patient ou...

    Authors: Xianzhe Fan, Ran Zhong, Hengrui Liang, Qiu Zhong, Hongtai Huang, Juan He, Yang Chen, Zixun Wang, Songlin Xie, Yu Jiang, Yuechun Lin, Sitong Chen, Wenhua Liang and Jianxing He
    Citation: BMC Cancer 2024 24:775
    Content type: Systematic Review Published on:

  33. Ubiquitin-specific peptidase 10 (USP10), a typical de-ubiquitinase, has been found to play a double-edged role in human cancers. Previously, we reported that the expression of USP10 was negatively correlated w...

    Authors: Zhi Zeng, Yina Li, Heng Zhou, Mingyang Li, Juan Ye, Dan Li, Yuxi Zhu, Yonggang Zhang, Xu Zhang, Yunchao Deng, Juan Li, Lijuan Gu and Jie Wu
    Citation: BMC Cancer 2024 24:773
    Content type: Research Published on:

  34. Wilms tumor is the most prevalent embryonal kidney malignancy in children worldwide. Previous genome-wide association study (GWAS) identified that LIM domain only 1 (LMO1) gene polymorphisms affected the suscepti...

    Authors: Wen Fu, Linqing Deng, Xiaosong Yan, Rui-Xi Hua, Jiao Zhang, Haixia Zhou, Changmi Deng, Suhong Li, Jiwen Cheng, Jichen Ruan, Jing He and Guochang Liu
    Citation: BMC Cancer 2024 24:772
    Content type: Research Published on:

  35. Wilms tumor (WT) is the most common pediatric embryonal tumor. Improving patient outcomes requires advances in understanding and targeting the multiple genes and cellular control pathways, but its pathogenesis...

    Authors: Qiang Zeng, Tingting Liu, Lilu Qin, Chen Wang, Guangbei Peng, Zhong Liu and Junfeng Tao
    Citation: BMC Cancer 2024 24:771
    Content type: Research Published on:

  36. Despite the existence of numerous studies investigating the diagnostic potential of blood microRNAs for colorectal cancer, the microRNAs under consideration vary widely, and comparative analysis of their diagn...

    Authors: Jianhao Xu, Lanfen Pan, Dan Wu, Liqian Yao, Wenqian Jiang, Jiarui Min, Song Xu and Zhiyong Deng
    Citation: BMC Cancer 2024 24:770
    Content type: Research Published on:

  37. Accumulating evidence indicates that the use of antibiotics (ATBs) in cancer patients is potentially correlated with patient prognosis. Interestingly, the use of these agents is not uncommon in colorectal canc...

    Authors: Mingyue Xu, Yuanyuan Chen, Panhua Li, Qianwen Ye, Shouhan Feng and Bing Yan
    Citation: BMC Cancer 2024 24:769
    Content type: Research Published on:

  38. Pancreatic ductal adenocarcinoma (PDAC) is a ‘difficult-to-treat’ entity. To forecast its prognosis, we introduced a new biomarker, SARIFA (stroma areactive invasion front areas), which are areas at the tumour...

    Authors: Przemyslaw Grochowski, Bianca Grosser, Florian Sommer, Andreas Probst, Johanna Waidhauser, Gerhard Schenkirsch, Nic G. Reitsam and Bruno Märkl
    Citation: BMC Cancer 2024 24:768
    Content type: Research Published on:

  39. Breast cancer (BrCa) is a predominant malignancy, with metastasis occurring in one in eight patients, nearly half of which target the bone, leading to serious complications such as pain, fractures, and comprom...

    Authors: Michael S. Bohanske, Kaveh Momenzadeh, Peer van der Zwaal, Frederik J.H. Hoogwater, Esther Cory, Peter Biggane, Brian D. Snyder and Ara Nazarian
    Citation: BMC Cancer 2024 24:767
    Content type: Research Published on:

  40. In oral squamous cell carcinoma (OSCC), the tumor-node-metastasis (TNM) staging system is a significant factor that influences prognosis and treatment decisions for OSCC patients. Unfortunately, TNM staging do...

    Authors: Wattawan Wongpattaraworakul, Allen Choi, Marisa R. Buchakjian, Emily A. Lanzel, Anand Rajan KD and Andrean L. Simons
    Citation: BMC Cancer 2024 24:766
    Content type: Research Published on:

  41. It is unclear whether hepatectomy, which ranges in invasiveness from partial to major hepatectomy, is safe and feasible for older adult patients. Therefore, we compared its postoperative complications and long...

    Authors: Hiroki Kanno, Kazuaki Hashimoto, Hisamune Sakai, Toshiro Ogata, Shogo Fukutomi, Masanori Akashi, Yuichi Goto, Takeshi Aoyagi, Masahiko Taniguchi and Toru Hisaka
    Citation: BMC Cancer 2024 24:765
    Content type: Research Published on:

  42. Clinically significant portal hypertension (CSPH) seriously affects the feasibility and safety of surgical treatment for hepatocellular carcinoma (HCC) patients. The aim of this study was to establish a new su...

    Authors: Jia-zhou Ye, Hua-ze Lu, Can Zeng, Guo Lei, Xiao-bo Wang, Jie Chen, Tao Bai, Fei-xiang Wu, Rong-yun Mai, Wei-xing Guo and Le-qun Li
    Citation: BMC Cancer 2024 24:764
    Content type: Research Published on:

  43. Cancer is among the leading cause of death worldwide. Chemotherapy is commonly used in cancer management and among the challenges in managing cancer patients is renal insufficiency (RI), which can be due to ca...

    Authors: Hamidu N. Rajabu, Sven Gudmund Hinderaker, Penina Mnandi and Ritah F. Mutagonda
    Citation: BMC Cancer 2024 24:763
    Content type: Research Published on:

  44. Despite evidence supporting the high correlation of the novel platelet-to-albumin ratio (PAR) with survival in diverse malignancies, its prognostic relevance in nasopharyngeal carcinoma (NPC) remains underexpl...

    Authors: Xin Hua, Fei Xu, Wei Shi, Zhi-Qing Long, Xin Huang, Fang-Fang Duan, Si-Fen Wang, Chao Zhang, Meng-Di Wang, Wei-Qiong Ni, Wen Xia, Jia-Yi Chen and Yun-Sheng Gao
    Citation: BMC Cancer 2024 24:762
    Content type: Research Published on:

  45. High-grade B-cell lymphoma (HGBCL), the subtype of non-Hodgkin lymphoma, to be relapsed or refractory in patients after initial therapy or salvage chemotherapy. Dual dysregulation of MYC and BCL2 is one of the...

    Authors: Lin Liu, Wenbin Mo, Miao Chen, Yi Qu, Pingping Wang, Ying Liang and Xiaojing Yan
    Citation: BMC Cancer 2024 24:761
    Content type: Research Published on:

  46. Psychosocial factors and socioeconomic status have been associated with incidence, survival, and quality of life among patients with head and neck cancer. We investigated the association between different psyc...

    Authors: Markus Atula, Timo Atula, Katri Aro, Heikki Irjala, Elina Halme, Anna Jouppila-Mättö, Petri Koivunen, Tommy Wilkman, Antti Mäkitie, Marko Elovainio and Laura Pulkki-Råback
    Citation: BMC Cancer 2024 24:760
    Content type: Research Published on:

  47. Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide. Inhibitor of kappa B kinase interacting protein (IKBIP) has been reported to promote glioma progression, but its role in o...

    Authors: Jiannan Hu, Chuanjing Dai, Zhaoji Ding, Yixiao Pan, Lingxiao Lu, Jiaqian Bao and Jingmin Zheng
    Citation: BMC Cancer 2024 24:759
    Content type: Research Published on:

  49. Nowadays, different therapeutic options are available for the first-line treatment of metastatic renal cell carcinoma (mRCC). Immuno-combinations are the standard first-line therapy in all mRCC patients regard...

    Authors: Sara Elena Rebuzzi, Giuseppe Fornarini, Alessio Signori, Sebastiano Buti, Giuseppe Procopio, Ugo De Giorgi, Sandro Pignata, Emanuele Naglieri, Marco Maruzzo, Giuseppe Luigi Banna, Pasquale Rescigno, Carlo Messina, Alvise Mattana, Umberto Basso and Davide Bimbatti
    Citation: BMC Cancer 2024 24:757
    Content type: Study Protocol Published on:

  50. Anti-vascular endothelial growth factor monoclonal antibody (anti-VEGF) or immune checkpoint inhibitors (ICIs) combined with chemotherapy are commonly administered to cancer patients. Although cancer patients ...

    Authors: Jianfen Zhu, Xiaokai Ding, Jianna Zhang, Bo Chen, Xiaohan You, Xinxin Chen and Tianxin Chen
    Citation: BMC Cancer 2024 24:756
    Content type: Research Published on:

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