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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 28 of 79

  1. Angiogenesis is a multistep process in which many growth factors and cytokines have an essential role. Vascular endothelial growth factor (VEGF) is a potent angiogenic agent that acts as a specific mitogen for...

    Authors: Kyung A Kwon, Sung Hyun Kim, Sung Yong Oh, Suee Lee, Jin-Yeong Han, Kyeong Hee Kim, Ri Young Goh, Hong Jo Choi, Ki Jae Park, Mee Sook Roh, Hyo-Jin Kim, Hyuk-Chan Kwon and Jong Hoon Lee
    Citation: BMC Cancer 2010 10:203
    Content type: Research article Published on:

  3. Local ablative techniques are emerging in patients with oligometastatic disease from colorectal carcinoma, commonly described as less invasive than surgical methods. This single arm cohort seeks to determine w...

    Authors: Ricarda Seidensticker, Robert Damm, Julia Enge, Max Seidensticker, Konrad Mohnike, Maciej Pech, Peter Hass, Holger Amthauer and Jens Ricke
    Citation: BMC Cancer 2018 18:882
    Content type: Research article Published on:

  5. Inflammatory cytokines may promote tumorigenesis. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine with regulatory properties over tumor suppressor proteins involved in bladder cancer...

    Authors: John A Taylor III, George A Kuchel, Poornima Hegde, Olga S Voznesensky, Kevin Claffey, John Tsimikas, Lin Leng, Richard Bucala and Carol Pilbeam
    Citation: BMC Cancer 2007 7:135
    Content type: Research article Published on:

  6. Dysregulation of microRNAs (miRNAs) is actively involved in the pathogenesis and tumorigenicity of colorectal cancer (CRC). miR-296 was found to play either oncogenic or tumor suppressive role in human cancers...

    Authors: Zheng He, Lianhua Yu, Shiyi Luo, Mingzhen Li, Junbo Li, Qi Li, Yi Sun and Chengbin Wang
    Citation: BMC Cancer 2017 17:140
    Content type: Research article Published on:

  7. The prognosis for patients with advanced FIGO stage III epithelial ovarian cancer remains poor despite the aggressive standard treatment, consisting of maximal cytoreductive surgery and platinum-based chemothe...

    Authors: Nathalie Rochet, Meinhard Kieser, Florian Sterzing, Sonja Krause, Katja Lindel, Wolfgang Harms, Michael H Eichbaum, Andreas Schneeweiss, Christof Sohn and Juergen Debus
    Citation: BMC Cancer 2011 11:41
    Content type: Study protocol Published on:

  8. In patients with high risk stage II and stage III colon cancer (CC), curative surgery followed by adjuvant FOLFOX-4 chemotherapy has become the standard of care. However, for 20 to 30 % of these patients, the ...

    Authors: Mehdi Karoui, Anne Rullier, Alain Luciani, Franck Bonnetain, Marie-Luce Auriault, Antony Sarran, Geneviève Monges, Hervé Trillaud, Karine Le Malicot, Karen Leroy, Iradj Sobhani, Armelle Bardier, Marie Moreau, Isabelle Brindel, Jean François Seitz and Julien Taieb
    Citation: BMC Cancer 2015 15:511
    Content type: Study protocol Published on:

  9. Epithelial-mesenchymal transition (EMT) is a crucial process in tumorigenesis since tumor cells attain fibroblast-like features enabling them to invade to surrounding tissue. Two transcription factors, TWIST and

    Authors: Anna Jouppila-Mättö, Mervi Närkiö-Mäkelä, Ylermi Soini, Matti Pukkila, Reijo Sironen, Hanna Tuhkanen, Arto Mannermaa and Veli-Matti Kosma
    Citation: BMC Cancer 2011 11:350
    Content type: Research article Published on:

  10. The inhibitor of apoptosis (IAP) protein Survivin and its splice variants are differentially expressed in breast cancer tissues. Our previous work showed Survivin is released from tumor cells via small membran...

    Authors: Salma Khan, Heather Ferguson Bennit, David Turay, Mia Perez, Saied Mirshahidi, Yuan Yuan and Nathan R Wall
    Citation: BMC Cancer 2014 14:176
    Content type: Research article Published on:

  11. Noggin and RNA-binding protein for multiple splicing 2 (RBPMS2) are known to regulate the expression of smooth muscle cells, endothelial cells, and osteoblasts. However, the prognostic role of combined Noggin ...

    Authors: Sang Hoon Chun, Eun Young Kim, Jung-Sook Yoon, Hye Sung Won, Kwangil Yim, Hye Won Hwang, Soon Auck Hong, Minho Lee, Su Lim Lee, Sung-Soo Kim, Der Sheng Sun and Yoon Ho Ko
    Citation: BMC Cancer 2021 21:558
    Content type: Research article Published on:

  12. Breast cancer (BCa) is the leading cause of cancer deaths among women. Reliable biomarkers for early diagnosis and metastasis prediction are essential to improve the prognosis of BCa. This study aimed to evalu...

    Authors: Li Jia, Guanhua Li, Na Ma, Aimin Zhang, Yunli Zhou, Li Ren and Dong Dong
    Citation: BMC Cancer 2022 22:760
    Content type: Research Published on:

  13. Breast cancer (BC) is one of the malignant diseases threatening the life and health of women worldwide. The CYP4B1 gene was abnormally expressed in BC and was associated with the prognosis of BC patients. This st...

    Authors: Yanhai Yin, Liangqian Tong, Zhenling Wan, Yanfang Sui, Fen Li, Qian Huang and Xinhan Zhao
    Citation: BMC Cancer 2023 23:1177
    Content type: Research Published on:

  15. The baculoviral IAP repeat containing 5 (BIRC5) related to epithelial-mesenchymal transition (EMT) plays a crucial role in the pathogenesis of hepatocellular carcinoma (HCC). However, it remains unclear whethe...

    Authors: Rongzhong Xu, Liubing Lin, Bo Zhang, Jian Wang, Fanchen Zhao, Xiaolin Liu, Yiping Li and Yan Li
    Citation: BMC Cancer 2021 21:687
    Content type: Research article Published on:

  16. Supradiaphragmatic lymph node metastases (SdLNM) are frequently identified using 18F-FDG positron emission tomography/computed tomography (PET/CT) in advanced epithelial ovarian cancers (AEOC). This study aimed t...

    Authors: In Ok Lee, Jung-Yun Lee, Hyun Jeong Kim, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Chang Young Lee, Won Jun Kang and Young Tae Kim
    Citation: BMC Cancer 2018 18:1165
    Content type: Research article Published on:

  17. The CDH1 gene codes for the epithelial-cadherin (E-cad) protein, which is embedded in the plasma membrane of epithelial cells to form adherens junctions. E-cad is known to be essential for maintaining the integri...

    Authors: Brihget Sicairos, Shorna Alam and Yuchun Du
    Citation: BMC Cancer 2023 23:441
    Content type: Research Published on:

  18. MicroRNAs (miRNAs) are small, non-coding RNA molecules involved in post-transcriptional gene regulation and have recently been shown to play a role in cancer metastasis. In solid tumors, especially breast canc...

    Authors: Augusto LF Marino, Adriane F Evangelista, René AC Vieira, Taciane Macedo, Ligia M Kerr, Lucas Faria Abrahão-Machado, Adhemar Longatto-Filho, Henrique CS Silveira and Marcia MC Marques
    Citation: BMC Cancer 2014 14:739
    Content type: Research article Published on:

  20. The transcription factor GLI1, a member of the GLI subfamily of Krüppel-like zinc finger proteins is involved in signal transduction within the hedgehog pathway. Aberrant hedgehog signalling has been implicate...

    Authors: Anette ten Haaf, Nuran Bektas, Sonja von Serenyi, Inge Losen, Elfriede Christel Arweiler, Arndt Hartmann, Ruth Knüchel and Edgar Dahl
    Citation: BMC Cancer 2009 9:298
    Content type: Research article Published on:

  21. The mitochondrial fission protein, Dynamin related protein 1 (Drp1), and its upstream protein calcium/calmodulin–dependent protein kinase I (CaMKI) play a critical role in chemoresistance in ovarian cancer (OV...

    Authors: Hideaki Tsuyoshi, Makoto Orisaka, Yuko Fujita, Meshach Asare-Werehene, Benjamin K. Tsang and Yoshio Yoshida
    Citation: BMC Cancer 2020 20:467
    Content type: Research article Published on:

  22. Several prognostic indexes (PI) have been developed in the brain metastases (BM) setting to help physicians tailor treatment options and stratify patients enrolled in clinical studies. The aim of our study was...

    Authors: Antoine-Laurent Braccini, David Azria, Simon Thezenas, Gilles Romieu, Jean-Marc Ferrero and William Jacot
    Citation: BMC Cancer 2013 13:70
    Content type: Research article Published on:

  23. By understanding Matrix Metalloprotease (MMP) dysregulation from a pan-cancer perspective, this study sheds light on the diagnostic potentials of MMPs across multiple neoplasms.

    Authors: Emily Gobin, Kayla Bagwell, John Wagner, David Mysona, Sharmila Sandirasegarane, Nathan Smith, Shan Bai, Ashok Sharma, Robert Schleifer and Jin-Xiong She
    Citation: BMC Cancer 2019 19:581
    Content type: Research article Published on:

  24. Tyrosine protein tyrosine kinase binding protein (TYROBP) binds non-covalently to activated receptors on the surface of various immune cells, and mediates signal transduction and cellular activation. It is dys...

    Authors: Jiajie Lu, Yuecheng Peng, Rihong Huang, Zejia Feng, Yongyang Fan, Haojian Wang, Zhaorong Zeng, Yunxiang Ji, Yezhong Wang and Zhaotao Wang
    Citation: BMC Cancer 2021 21:723
    Content type: Research Published on:

  25. Young breast cancer (BC) patients less than 45 years old are at higher risk of dying from the disease when compared to their older counterparts. However, specific risk factors leading to this poorer outcome ha...

    Authors: Jinlong Jian, Qing Yang, Yongzhao Shao, Deborah Axelrod, Julia Smith, Baljit Singh, Stephanie Krauter, Luis Chiriboga, Zhaoxu Yang, Jinqing Li and Xi Huang
    Citation: BMC Cancer 2013 13:307
    Content type: Research article Published on:

  26. Ovarian cancer (OV) is one of the most common malignant tumors of gynecology oncology. The lack of effective early diagnosis methods and treatment strategies result in a low five-year survival rate. Also, immu...

    Authors: Shibai Yan, Juntao Fang, Yongcai Chen, Yong Xie, Siyou Zhang, Xiaohui Zhu and Feng Fang
    Citation: BMC Cancer 2020 20:1205
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Cancer 2021 21:55

  27. Five-year survival in patients with localized prostate cancer (PCa) is nearly 100%, but metastatic disease still remains incurable. Clinical management of metastatic patients has become increasingly complex as...

    Authors: Mariarosa Pascale, Che Ngwa Azinwi, Barbara Marongiu, Gianfranco Pesce, Flavio Stoffel and Enrico Roggero
    Citation: BMC Cancer 2017 17:651
    Content type: Research article Published on:

  28. Due to improved survival rate, gastric cancer (GC) patients have an increased risk of developing multiple primary cancer (MPC). The purpose of this study is to evaluate the clinicopathological features of MPC ...

    Authors: Chan Kim, Hong Jae Chon, Beodeul Kang, Kiyeol Kim, Hei-Cheul Jeung, Hyun Cheol Chung, Sung Hoon Noh and Sun Young Rha
    Citation: BMC Cancer 2013 13:394
    Content type: Research article Published on:

  29. HIPEC is an emerging procedure to treat peritoneal metastasis of gastric cancer. Data about HIPEC in locally advanced gastric cancer is scarce. The purpose of this trial is to evaluate the safety and toxicity ...

    Authors: Biao Fan, Zhaode Bu, Ji Zhang, Xianglong Zong, Xin Ji, Tao Fu, Ziyu Jia, Yinan Zhang and Xiaojiang Wu
    Citation: BMC Cancer 2021 21:216
    Content type: Research article Published on:

  30. P21-activated protein kinase 1 (PAK1), a main downstream effector of small Rho GTPases, is overexpressed in many malignancies. PAK1 overexpression is associated with poor prognosis in some tumor types, includi...

    Authors: Juan Han, Feng Wang, Shu-qiang Yuan, Ying Guo, Zhao-lei Zeng, Li-ren Li, Jing Yang, De-sen Wang, Mei-yuan Liu, Han Zhao, Kai-yan Liu, Jian-wei Liao, Qing-feng Zou and Rui-hua Xu
    Citation: BMC Cancer 2014 14:650
    Content type: Research article Published on:

  31. Recent studies have shown that deficient mismatch repair (dMMR) rectal cancer may be related to treatment resistance, resulting in a worse prognosis than proficient MMR (pMMR) rectal cancer. The purpose of thi...

    Authors: Kemin Ni, Yixiang Zhan, Zhaoce Liu, Zhen Yuan, Shuyuan Wang, Xuan-zhu Zhao, Hangyu Ping, Yaohong Liu, Wanting Wang, Suying Yan, Ran Xin, Qiurong Han, Qinghuai Zhang, Guoxun Li, Xipeng Zhang, Guihua Wang…
    Citation: BMC Cancer 2023 23:1013
    Content type: Research Published on:

  33. Non-muscle invasive bladder cancers (NMIBC: pTa, pT1) are characterised by a high risk of recurrence and/or progression. Identification of prognostic markers is needed to improve both diagnosis and management ...

    Authors: Christel Mathis, Isabelle Lascombe, Franck Monnien, Hugues Bittard, François Kleinclauss, Isabelle Bedgedjian, Sylvie Fauconnet and Séverine Valmary-Degano
    Citation: BMC Cancer 2018 18:1239
    Content type: Research article Published on:

  34. Synchronous multiple primary esophageal squamous cell carcinoma (S-MPESCC) refers to more than one primary esophageal carcinoma detected in a solitary patient at the time of initial presentation. The purpose o...

    Authors: Yueyang Yang, Peng Tang, Mingquan Ma, Hongdian Zhang, Haitong Wang, Kai Zhu, Wanyi Xiao, Lei Gong and Zhentao Yu
    Citation: BMC Cancer 2022 22:1191
    Content type: Research Published on:

  35. Postoperative chemoradiotherapy (CRT) is a standard therapy for patients with high-risk factors for head and neck squamous cell carcinoma, including positive margin and extra-nodal extension (ENE). However, th...

    Authors: Ari Nishimura, Tomoya Yokota, Satoshi Hamauchi, Yusuke Onozawa, Akifumi Notsu, Fuyuki Sato, Takeshi Kawakami, Hirofumi Ogawa, Tsuyoshi Onoe and Takashi Mukaigawa
    Citation: BMC Cancer 2022 22:1101
    Content type: Research Published on:

  36. There remains uncertainty in whether vitamin D status affects cancer survival. We investigated whether vitamin D (± calcium) supplementation affects cancer survival in women.

    Authors: Mona Jeffreys, Maria Theresa Redaniel and Richard M. Martin
    Citation: BMC Cancer 2015 15:670
    Content type: Research article Published on:

  37. Cancer patients with brain metastases (BMs) require multidisciplinary care, and treatment facility may play a role. This study aimed to investigate the impact of receiving treatment at academic centers on the ...

    Authors: Saber Amin, Michael Baine, Jane Meza and Chi Lin
    Citation: BMC Cancer 2021 21:387
    Content type: Research article Published on:

  38. Pain is a common, debilitating, and feared symptom, including among cancer survivors. However, large-scale population-based evidence on pain and its impact in cancer survivors is limited. We quantified the pre...

    Authors: Grace Joshy, Saman Khalatbari-Soltani, Kay Soga, Phyllis Butow, Rebekah Laidsaar-Powell, Bogda Koczwara, Nicole M. Rankin, Sinan Brown, Marianne Weber, Carolyn Mazariego, Paul Grogan, John Stubbs, Stefan Thottunkal, Karen Canfell, Fiona M. Blyth and Emily Banks
    Citation: BMC Cancer 2023 23:774
    Content type: Research article Published on:

  39. For brain metastases from non-specific primary tumors, the most frequently used and validated clinical prognostic assessment tool is Karnofsky performance status (KPS). Given the lack of prognostic factors of ...

    Authors: Jun Imaizumi, Dai Shida, Yoshitaka Narita, Yasuji Miyakita, Taro Tanabe, Atsuo Takashima, Narikazu Boku, Hiroshi Igaki, Jun Itami and Yukihide Kanemitsu
    Citation: BMC Cancer 2019 19:755
    Content type: Research article Published on:

  40. The study was aimed to quantitatively detect mRNA levels of the catalytic subunit of telomerase (hTERT) in both peripheral blood and circulating tumor cells (CTCs) of patients with nasopharyngeal carcinoma (NP...

    Authors: Xinsa Fu, Congxiang Shen, Huigang Wang, Fang Chen, Guanxue Li and Zhong Wen
    Citation: BMC Cancer 2017 17:479
    Content type: Research article Published on:

  41. In treatment-refractory liver dominant metastatic colorectal cancer, the role of liver directed therapies still is unclear. We sought to determine a prognostic score for Y90 radioembolization in these patients.

    Authors: Robert Damm, Ricarda Seidensticker, Gerhard Ulrich, Leonie Breier, Ingo G. Steffen, Max Seidensticker, Benjamin Garlipp, Konrad Mohnike, Maciej Pech, Holger Amthauer and Jens Ricke
    Citation: BMC Cancer 2016 16:509
    Content type: Research article Published on:

  42. Cancer cells induce the infiltration of various immune cells that are located or distributed in different sites and play multiple roles, which have recently been proposed to predict clinical outcomes. We there...

    Authors: Jie Wang, Shu Tian, Ji Sun, Jiahao Zhang, Lan Lin and Chunyan Hu
    Citation: BMC Cancer 2020 20:731
    Content type: Research article Published on:

  43. The situation of patients developing multiple primary cancers is becoming more frequent and graver. This study investigated the risks of developing second primary cancers that are related to first primary canc...

    Authors: Pariyada Tanjak, Bhoom Suktitipat, Nutchavadee Vorasan, Panudeth Juengwiwattanakitti, Benjarat Thiengtrong, Cholticha Songjang, Suwanit Therasakvichya, Somsri Laiteerapong and Vitoon Chinswangwatanakul
    Citation: BMC Cancer 2021 21:1045
    Content type: Research Published on:

  44. To investigate the potential correlation between piwi-like RNA-mediated gene silencing 1 (PIWIL1) polymorphisms and susceptibility to epithelial ovarian cancer (EOC).

    Authors: Shanshan Liu, Yaping Yan, Zhizhong Cui, Haipeng Feng, Fengmei Zhong, Ziguang Liu, Yan Li, Xiang Ou and Wenjuan Li
    Citation: BMC Cancer 2023 23:1149
    Content type: Research Published on:

  45. The tripartite motif (TRIM) proteins have been reported to play crucial roles in various malignancies. However, the clinical significance of TRIM proteins in colorectal cancer (CRC) remains controversial. This...

    Authors: Ying Wu, Chen Chen, Xian Hua, Chunhua Zhao and Han Min
    Citation: BMC Cancer 2024 24:537
    Content type: Research Published on:

  46. Our objective was to identify risk factors affecting overall survival (OS) and cancer-specific survival (CSS) and build nomograms to predict survival based on a large population-based cohort.

    Authors: Chaobin He, Yu Zhang, Zhiyuan Cai and Xiaojun Lin
    Citation: BMC Cancer 2019 19:178
    Content type: Research article Published on:

  47. Prognostic factors aid in the stratification and treatment of cancer. This study evaluated the prognostic significance of human epidermal growth factor receptor (HER) family members (HER1–4) expression in pati...

    Authors: Qin Li, Lei Zhang, XiuHong Li, Han Yan, Liuting Yang, Yingying Li, Teng Li, Jing Wang and Bangwei Cao
    Citation: BMC Cancer 2016 16:910
    Content type: Research article Published on:

  48. With the increase in cancer survivors, more pancreatic ductal adenocarcinomas (PDACs) are developing as second primary cancers. Whether a prior cancer has an inferior impact on survival outcomes in patients wi...

    Authors: Chaobin He, Yu Zhang, Zhiyuan Cai and Xiaojun Lin
    Citation: BMC Cancer 2019 19:509
    Content type: Research article Published on:

  49. One of the causes of colon and gastric cancer is the dysregulation of carcinogenic genes, tumor inhibitors, and micro-RNA. The purpose of this study is to apply rs10811661 polymorphism in CDKN2A /B gene as an ...

    Authors: Maria Beihaghi, Reza Sahebi, Mohammad Reza Beihaghi, Raheleh Khosravi Nessiani, Majedeh Ramian Yarasmi, Sajad Gholamalizadeh, Fatemeh Shahabnavaie and Mitra shojaei
    Citation: BMC Cancer 2023 23:985
    Content type: Research Published on:

  50. The newly discovered metastasis-associated in colon cancer-1 (MACC1) gene is a key regulator of the HGF/MET pathway. Deregulation of HGF/MET signaling is reported as a prognostic marker for tumorigenesis, earl...

    Authors: Alois H Lang, Simone Geller-Rhomberg, Thomas Winder, Nicole Stark, Klaus Gasser, Bernd Hartmann, Bertram Kohler, Ina Grizelj, Heinz Drexel and Axel Muendlein
    Citation: BMC Cancer 2012 12:20
    Content type: Research article Published on:

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