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  1. Crohn’s disease (CD), a prominent manifestation of chronic gastrointestinal inflammation, and breast cancer (BC), seemingly disparate in the medical domain, exhibit a shared characteristic. This convergence ar...

    Authors: Xin Yu, Yushuai Yu, Xiewei Huang, Zirong Jiang, Qing Wang, Xiaoqin Yu and Chuangui Song
    Citation: BMC Cancer 2024 24:1134
    Content type: Research Published on:

  2. Sunitinib, a newly developed multi-targeted tyrosine kinase inhibitor (TKI), has become a common therapeutic option for managing advanced renal cell carcinoma (RCC). Examining the mechanism underlying the inte...

    Authors: Jinyu Hu, Hailun Xia, Xiaohai Chen, Xinhao Xu, Hua-Lu Wu, Yuxin Shen, Ren-ai Xu and Wenzhi Wu
    Citation: BMC Cancer 2024 24:1131
    Content type: Research Published on:

  3. Breast cancer metastasis remains the leading cause of cancer-related deaths in women worldwide. Infiltration of tumor-associated macrophages (TAMs) in the tumor stroma is known to be correlated with reduced ov...

    Authors: Bhawna Deswal, Urmi Bagchi, Manas Kumar Santra, Manoj Garg and Sonia Kapoor
    Citation: BMC Cancer 2024 24:1129
    Content type: Research Published on:

  4. Lung cancer, a major global health concern, disproportionately impacts low socioeconomic status (SES) patients, who face suboptimal care and reduced survival. This study aimed to evaluate the prognostic perfor...

    Authors: Jiaxin Cui, Zifen An, Xiaozhou Zhou, Xi Zhang, Yuying Xu, Yaping Lu and Liping Yu
    Citation: BMC Cancer 2024 24:1128
    Content type: Research Published on:

  5. Survival rates of breast cancer (BC) patients are particularly low in rural regions in sub-Saharan Africa (SSA) which is due to limited access to therapy. In recent years, gene expression profiling (GEP) of BC...

    Authors: Judith Katharina Ballé, Martina Vetter, Tariku Wakuma Kenea, Pia Eber-Schulz, Christian Reibold, Hannes-Viktor Ziegenhorn, Kathrin Stückrath, Claudia Wickenhauser, Adamu Addissie, Pablo Santos, Eva Johanna Kantelhardt, Sefonias Getachew and Marcus Bauer
    Citation: BMC Cancer 2024 24:1127
    Content type: Research Published on:

  6. Lung cancer, particularly non-small cell lung cancer (NSCLC), remains a significant cause of cancer-related mortality, with drug resistance posing a substantial obstacle to effective therapy. LncRNAs have emer...

    Authors: Ruihua Liu, Jiemin Wang, Lichun Zhang, Shu Wang, Xiangnan Li, Yueshi Liu and Haiquan Yu
    Citation: BMC Cancer 2024 24:1126
    Content type: Research Published on:

  7. In the first year of the COVID-19 pandemic, data projections indicated an increase in cancer mortality for the following years due to the overload of health services and the replacement of health priorities. T...

    Authors: Amanda Ramos da Cunha and José Leopoldo Ferreira Antunes
    Citation: BMC Cancer 2024 24:1125
    Content type: Research Published on:

  8. The gut microbiome is thought to play an important role in the development of colorectal cancer (CRC). However, as the gut microbiome varies widely based on diet, we sought to investigate the gut microbiome ch...

    Authors: Bawantha Dilshan Gamage, Diyanath Ranasinghe, AGP Sahankumari and Gathsaurie Neelika Malavige
    Citation: BMC Cancer 2024 24:1124
    Content type: Research Published on:

  9. Bortezomib, lenalidomide, and dexamethasone (VRD), and bortezomib, doxorubicin, and dexamethasone (PAD), are commonly used in induction regimens for patients with newly diagnosed multiple myeloma (NDMM) in Chi...

    Authors: Dong Liang, Shenrui Bai, Demei Feng, Guanjun Chen, Yang Liang and Hua Wang
    Citation: BMC Cancer 2024 24:1123
    Content type: Research Published on:

  11. Nonresectable gastric cancer develops rapidly; thus, monitoring disease progression especially in patients receiving nivolumab as late-line therapy is important. Biomarkers may facilitate the evaluation of niv...

    Authors: Michiko Inukai, Tomohiko Nishi, Hiroshi Matsuoka, Kazuhiro Matsuo, Kazumitsu Suzuki, Akiko Serizawa, Shingo Akimoto, Masaya Nakauchi, Tsuyoshi Tanaka, Kenji Kikuchi, Susumu Shibasaki, Ichiro Uyama and Koichi Suda
    Citation: BMC Cancer 2024 24:1121
    Content type: Research Published on:

  12. Transcatheter arterial chemoembolization (TACE) combined with targeted therapy and immunotherapy can significantly improve the prognosis of patients with hepatocellular carcinoma (HCC). T-cell immunoreceptor w...

    Authors: Yuan Guo, Xiong Yang, Wei Li Xia, Wen Bo Zhu, Fang Ting Li, Hong Tao Hu and Hai Liang Li
    Citation: BMC Cancer 2024 24:1120
    Content type: Research Published on:

  15. Gastric cancer (GC) ranks among the prevalent types of cancer, and its progression is influenced by the tumor microenvironment (TME). A comprehensive comprehension of the TME associated with GC has the potenti...

    Authors: Dapeng Chen, Wen Tong, Bing Ang, Yi Bai, Wenhui Dong, Xiyue Deng, Chunjiong Wang and Yamin Zhang
    Citation: BMC Cancer 2024 24:1117
    Content type: Research Published on:

  17. Nasopharyngeal carcinoma (NPC) is diagnosed relatively late and has a poor prognosis, requiring early detection to reduce the disease burden. This diagnostic test accuracy meta-analysis evaluated the serologic...

    Authors: Han Liu, Lin Lei, Song Song, Xianyi Geng, Kaihao Lin, Ni Li, Wanqing Chen, Ji Peng and Jiansong Ren
    Citation: BMC Cancer 2024 24:1115
    Content type: Research Published on:

  18. Lung cancer is one of the most common cancers and causes of cancer death in Canada. Some previous literature suggests that socioeconomic inequalities in lung cancer screening, treatment and survival may exist....

    Authors: Arlinda Ruco, Aisha K. Lofters, Hong Lu, Nancy N. Baxter, Sara Guilcher, Alexander Kopp, Mandana Vahabi and Geetanjali D. Datta
    Citation: BMC Cancer 2024 24:1114
    Content type: Research Published on:

  19. This meta-analysis aims to clarify the association between the TNF-α -308G > A and − 238G > A polymorphisms and lung cancer risk.

    Authors: Seyed Masoud HaghighiKian, Ahmad Shirinzadeh-Dastgiri, Reza Ershadi, Mohammad Vakili-Ojarood, Maedeh Barahman, Seyed Alireza Dastgheib, Fatemeh Asadian, Amirmasoud Shiri, Maryam Aghasipour, Amirhossein Rahmani, Kazem Aghili and Hossein Neamatzadeh
    Citation: BMC Cancer 2024 24:1113
    Content type: Research Published on:

  20. Hepatocellular carcinoma (HCC), a prevalent primary malignant tumor, is notorious for its high mortality rate. Despite advancements in HCC treatment, patient outcomes remain suboptimal. This study endeavors to...

    Authors: Yan Dong, Xinyi Chen, Shen Yang, Yilong Fu, Liangyu Wang, Xueping Gao, Di Chen and Lixia Xu
    Citation: BMC Cancer 2024 24:1112
    Content type: Research Published on:

  21. Risk-stratified approaches to breast screening show promise for increasing benefits and reducing harms. But the successful implementation of such an approach will rely on public acceptability. To date, researc...

    Authors: Charlotte Kelley-Jones, Suzanne E. Scott and Jo Waller
    Citation: BMC Cancer 2024 24:1111
    Content type: Research Published on:

  22. The prognosis of patients with hepatocellular cancer is substantially correlated with the abnormal expression of growing long non-coding RNA small nucleolar host gene RNA (SNHG) families in liver cancer tissue...

    Authors: Sheng-qi Du, Ya-Tong Liu, Fen Yang, Pei-xue Wang and Jun Zhang
    Citation: BMC Cancer 2024 24:1110
    Content type: Systematic Review Published on:

  23. Meaningful engagement with stakeholders in research demands intentional approaches. This paper describes the development of a framework to guide stakeholder engagement as research partners in a pragmatic trial...

    Authors: Cameron Macdonald, Margaret Fitch, Katherine A. Hutcheson, Timothy M. McCulloch and Rosemary Martino
    Citation: BMC Cancer 2024 24:1109
    Content type: Comment Published on:

  24. Patients with head and neck cancers (HNC) experience many transitions in care (TiC), occurring when patients are transferred between healthcare providers and/or settings. TiC can compromise patient safety, dec...

    Authors: Jaling Kersen, Pamela Roach, Shamir Chandarana, Paul Ronksley and Khara Sauro
    Citation: BMC Cancer 2024 24:1108
    Content type: Research Published on:

  25. Women with breast cancer face many barriers to return to work (RTW) after their cancer. The main objective of the FASTRACS-RCT is to evaluate the impact of the FASTRACS (Facilitate and Sustain Return to Work a...

    Authors: Jean-Baptiste Fassier, Laure Guittard, Béatrice Fervers, Sabrina Rouat, Philippe Sarnin, Julien Carretier, Guillaume Broc, Laurent Letrilliart, Julien Péron and Marion Lamort-Bouché
    Citation: BMC Cancer 2024 24:1107
    Content type: Study Protocol Published on:

  26. This study aims to investigate preoperative prognostic factors available for intrahepatic cholangiocarcinoma (ICC) patients and propose a new preoperative prognostic scoring system for ICC that combines CA19-9...

    Authors: Shilei Bai, Xiaodong Shi, Yizhe Dai, Huifeng Wang, Yong Xia, Jian Liu and Kui Wang
    Citation: BMC Cancer 2024 24:1106
    Content type: Research Published on:

  27. SEPT9 is a pivotal cytoskeletal GTPase that regulates diverse biological processes encompassing mitosis and cytokinesis. While previous studies have implicated SEPT9 in tumorigenesis and development; comprehensiv...

    Authors: Wenwen Wang, Xiaochen Zhang, Ping Gui, Qizhen Zou, Yuzhou Nie, Shenglin Ma and Shirong Zhang
    Citation: BMC Cancer 2024 24:1105
    Content type: Research Published on:

  28. The purpose of this retrospective study was to compare the safety and feasibility of single-intercostal totally minimally invasive Ivor Lewis esophagectomy (MIIE) with those of multiple-intercostal MIIE.

    Authors: Jinghao Huang, Yifan Yu, Zixiang Wu, Chuanqiang Wu, Jinsheng Li, Zhiling Lou and Ming Wu
    Citation: BMC Cancer 2024 24:1104
    Content type: Research Published on:

  29. Cisplatin (CDDP) remains a key agent in the treatment of muscle-infiltrating bladder carcinoma (MIBC). However, a proportion of MIBC patients do not respond to chemotherapy, which may be caused by the increase...

    Authors: Patrik Palacka, Andrea Holíčková, Jan Roška, Peter Makovický, Miroslava Vallová, Csaba Biró, Eveline Órásová, Jana Obertová, Jozef Mardiak, Thomas A. Ward, Karol Kajo and Miroslav Chovanec
    Citation: BMC Cancer 2024 24:1103
    Content type: Research Published on:

  30. According to GLOBOCAN 2020 Breast cancer is the most common cancer among women and the prevalence is increasing worldwide and in Ethiopia. This review assessed studies conducted in Ethiopia on the clinical fea...

    Authors: Firaol Guyassa Dandena, Berhanetsehay Teklemariam Teklewold, Tadele Dana Darebo and Yisihak Debodina Suga
    Citation: BMC Cancer 2024 24:1102
    Content type: Systematic Review Published on:

  31. Neoadjuvant chemoradiotherapy (nCRT) followed by surgery remains a standard of care for resectable esophageal cancer (EC), and definitive chemoradiotherapy (dCRT) is an alternative for unresectable diseases. H...

    Authors: Jiacheng Yao, Xinyu Zhao, Jun Chen, Tingting Liu, Yaowen Song and Jun Dang
    Citation: BMC Cancer 2024 24:1101
    Content type: Research Published on:

  32. Regulatory T (Treg) cells reportedly play crucial roles in tumor angiogenesis as well as antitumor immunity. In order to explore their therapeutic potential, we investigated the precise prognostic impact of Tr...

    Authors: Asami Suto, Takeo Minaguchi, Nan Qi, Kaoru Fujieda, Hiroya Itagaki, Yuri Tenjimbayashi, Ayumi Shikama, Nobutaka Tasaka, Azusa Akiyama, Sari Nakao, Chigusa Nakahashi-Oda, Yusuke Kobayashi, Akira Shibuya and Toyomi Satoh
    Citation: BMC Cancer 2024 24:1100
    Content type: Research Published on:

  33. Glioblastoma multiforme (GBM) is the most malignant brain tumor, with a poor prognosis and life expectancy of 14–16 months after diagnosis. The standard treatment for GBM consists of surgery, radiotherapy, and...

    Authors: Nastaran Afsordeh, Safura Pournajaf, Hadi Bayat, Fatemeh Mohajerani, Amir Shojaei, Javad Mirnajafi-Zadeh and Mohammad Hossein Pourgholami
    Citation: BMC Cancer 2024 24:1099
    Content type: Research Published on:

  34. Liver cancer (LC) is frequently preceded by cirrhosis and poses a significant public health challenge in the United States (US). Recent decades have seen notable shifts in the epidemiological patterns of LC, y...

    Authors: Omar Al Ta’ani, Yazan Al-Ajlouni, Balaji Jagdish, Himsikhar Khataniar, Wesam Aleyadeh, Farah Al-Bitar and Tavankit Singh
    Citation: BMC Cancer 2024 24:1098
    Content type: Research Published on:

  35. In oncology, the suffering of patients and the burnout of health professionals are key issues. Mindfulness meditation is a holistic approach that can help to improve well-being. While numerous studies have sho...

    Authors: Virginie Prevost, Titi Tran, Alexandra Leconte, Justine Lequesne, Marie Fernette, Carine Segura, Sylvie Chevigné, Mylène Gouriot and Bénédicte Clarisse
    Citation: BMC Cancer 2024 24:1097
    Content type: Study Protocol Published on:

  36. The effectiveness of palliative gastrectomy for advanced GC remains a topic of debate. This study sought to establish whether palliative gastrectomy has an impact on prolonging survival.

    Authors: Desheng Luo, Hongtao Xu, Chuan Jiang, Jingjing Zheng, Dan Wu, Laizhen Tou, Haifeng Que and Zheng Sun
    Citation: BMC Cancer 2024 24:1096
    Content type: Research Published on:

  38. Dysregulated splicing events are a common phenomenon in cancer with the Serine-arginine-rich splicing factor (SRSF) family emerging as pivotal regulators of gene expression, exerting influence over constitutiv...

    Authors: Sakshi Sharma, Manasi Mittal, Akanksha Shukla, Jiyauddin Khan, Veronique Dinand and Daman Saluja
    Citation: BMC Cancer 2024 24:1094
    Content type: Research Published on:

  39. As assessment tools of nutritional status, the controlling nutritional status (CONUT) and modified controlling nutritional status (mCONUT) score are associated with survival in various cancers. We aimed to inv...

    Authors: Juan Fu, Xintian Xu, Mengxing Tian, Hongbing Wang and Xin Jin
    Citation: BMC Cancer 2024 24:1093
    Content type: Research Published on:

  40. Despite the severe impact of COVID-19 on cancer patients, data on COVID-19 outcomes in cancer patients from low- and middle-income countries is limited. We conducted a large study about the mortality rate of C...

    Authors: Monireh Sadat Seyyedsalehi, Marveh Rahmati, Reza Ghalehtaki, Azin Nahvijou, Bita Eslami, Zoha Shaka, Seyed Farshad Allameh and Kazem Zendehdel
    Citation: BMC Cancer 2024 24:1092
    Content type: Research Published on:

  41. MicroRNAs (miRNAs) are single RNA molecules that act as global regulators of gene expression in mammalian cells and thus constitute attractive targets in treating cancer. Here we aimed to investigate the possi...

    Authors: Emad Dabous, Mai Alalem, Ahmed M. Awad, Khaled A. Elawdan, Ahmed M. Tabl, Shorouk Elsaka, Walid Said, Adel A. Guirgis and Hany Khalil
    Citation: BMC Cancer 2024 24:1091
    Content type: Research Published on:

  42. Axillary lymph node dissection (ALND) is a standard procedure for early-stage breast cancer (BC) patients with three or more positive sentinel lymph nodes (SLNs). However, ALND can lead to significant postoper...

    Authors: Xiangli Xie, Yutong Fang, Lifang He, Zexiao Chen, Chunfa Chen, Huancheng Zeng, Bingfeng Chen, Guangsheng Huang, Cuiping Guo, Qunchen Zhang and Jundong Wu
    Citation: BMC Cancer 2024 24:1090
    Content type: Research Published on:

  43. The log odds of positive lymph nodes (LODDS) was considered a superior staging system to N stage in colon cancer, yet its value in determining the optimal duration of adjuvant chemotherapy for stage III colon ...

    Authors: Weili Zhang, Zhenlin Hou, Linjie Zhang, Xuanlin Hong, Weifeng Wang, Xiaojun Wu, Dongbo Xu, Zhenhai Lu, Jianxun Chen and Jianhong Peng
    Citation: BMC Cancer 2024 24:1088
    Content type: Research Published on:

  46. Colorectal cancer is the third most common cancer and the second leading cause of cancer death. There are limited therapeutic options for the treatment of locally advanced or metastatic colorectal cancers whic...

    Authors: Yu Cheng, Zan Teng, Yanqiao Zhang, Bo Jin, Zhendong Zheng, Li Man, Zhenghua Wang, Yuee Teng, Ping Yu, Jing Shi, Ying Luo, Ying Wang, Jingdong Zhang, Huijuan Zhang, Jiwei Liu, Hao Chen…
    Citation: BMC Cancer 2024 24:1082
    Content type: Research Published on:

  47. Mutated human epidermal growth factor receptor 2 (HER2) is an oncogene with critical pathogenic roles in breast cancer. HER2-low-positive breast cancer is a recently described subtype. We aimed to explore the cli...

    Authors: Yusuke Gokon, Yuka Nakashima, Yusuke Ohki, Takahiro Ogino, Keiichiro Hatoyama, Kenji Shimizu, Toshiaki Kashiwadate, Kazunori Katsura, Takayuki Abe and Koichiro Sato
    Citation: BMC Cancer 2024 24:1081
    Content type: Research Published on:

  49. Due to the complex pathophysiological mechanisms involved in cancer progression and metastasis, current therapeutic approaches lack efficacy and have significant adverse effects. Therefore, it is essential to ...

    Authors: Sajad Fakhri, Seyed Zachariah Moradi, Seyed Yahya Moradi, Sarina Piri, Behrang Shiri Varnamkhasti, Sana Piri, Mohammad Reza Khirehgesh, Ankur Bishayee, Nicolette Casarcia and Anupam Bishayee
    Citation: BMC Cancer 2024 24:1079
    Content type: Systematic Review Published on:

  50. Introduction. To date, radical surgery remains the best curative option in patients with early-stage lung cancer. In patients with small lung lesions, video-assisted thoracic surgery (VATS) should be increasin...

    Authors: Eleonora Della Beffa, Paraskevas Lyberis, Giulio Luca Rosboch, Alberto Arezzo, Filippo Lococo, Laura Carena, Elisa Sciorsci, Valentina Monica, Paolo Olivo Lausi, Veronica Dusi, Francesco Paolo Busardò, Elena Buffa, Rachele Stefania, Giovannino Ciccone, Chiara Monagheddu, Beatrice Maria Capello…
    Citation: BMC Cancer 2024 24:1078
    Content type: Study Protocol Published on:

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