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  1. Neoadjuvant chemotherapy (NAC) for breast cancer enables pathological complete response (pCR) in patients initially diagnosed with axillary lymph node metastases, potentially obviating the need for axillary ly...

    Authors: Wuzhen Chen, Liwei Pang, Xiaoyan Jin, Hailang Chen and Jian Huang
    Citation: BMC Cancer 2024 24:1276
    Content type: Study Protocol Published on:

  2. Colorectal cancer (CRC) is the third most common malignancy, with increasing prevalence and mortality. How the ethoxy-erianin phosphate (EBTP) mediates CRC development remains unclear. Therefore, the current s...

    Authors: Shaoqun Liu, Fei Teng, Yuxin Lu, Yanqing Zhu, Xin Liang, Fanhong Wu, Jianwen Liu, Wenming Zhou, Chang Su and Yiou Cao
    Citation: BMC Cancer 2024 24:1275
    Content type: Research Published on:

  3. The objective of this study was to develop nomograms for predicting outcomes following immunotherapy in patients diagnosed with intrahepatic cholangiocarcinoma (ICC).

    Authors: Sihui Zhu, Yuncheng Jin, Juan Zhang, Minzheng Zhou, Baorui Liu, Xiufeng Liu, Jie Shen and Chao Chen
    Citation: BMC Cancer 2024 24:1274
    Content type: Research Published on:

  4. Papillary thyroid cancer (PTC) is the most common thyroid malignancy, characterized by its slow progression and favorable prognosis. This study re-evaluates the efficacy of radioactive iodine (RAI) therapy ver...

    Authors: Seckin Bilgic, Rasimcan Meral, M. Sait Sağer and Kerim Sönmezoğlu
    Citation: BMC Cancer 2024 24:1273
    Content type: Research Published on:

  5. Ovarian cancer is the fifth most prevalent cancer in women. Chemotherapy is a major treatment option for patients with advanced ovarian cancer (OC). Quinoline-2-thione and its derivatives are potential candida...

    Authors: Jin-Jin Zhao, Jie Zhao, Fei Lin, Li-Li Xu, Zhi-Gang Chen, Yu-Qin Jiang and Guo-An Zhao
    Citation: BMC Cancer 2024 24:1272
    Content type: Research Published on:

  6. As we delve into the intricate world of venetoclax combination therapy in relapsed or refractory acute myeloid leukemia (AML), our exploration not only aims to contribute to the current body of knowledge but a...

    Authors: Ning Jiao, Lina Shi, Shaohua Wang, Yonghao Sun, Yujun Bai and Dengshan Zhang
    Citation: BMC Cancer 2024 24:1271
    Content type: Systematic Review Published on:

  7. Lung cancer (LC) occupies an important position in the lethality of cancer patients. Acquired resistance to gefitinib in lung adenocarcinoma (LUAD) seriously affects the therapeutic efficacy of LC. Thus, it is...

    Authors: Dongxiao Ding, Wenjun Shang, Ke Shi, Junjie Ying, Li Wang, Zhongjie Chen and Chong Zhang
    Citation: BMC Cancer 2024 24:1270
    Content type: Research Published on:

  8. Angiogenesis is associated with tumour growth, infiltration, and metastasis. This study aimed to detect the mechanisms of angiogenesis-related genes (ARGs) in multiple myeloma (MM) and to construct a new progn...

    Authors: Rui Hu, Fengyu Chen, Xueting Yu, Zengzheng Li, Yujin Li, Shuai Feng, Jianqiong Liu, Huiyuan Li, Chengmin Shen, Xuezhong Gu and Zhixiang Lu
    Citation: BMC Cancer 2024 24:1269
    Content type: Research Published on:

  9. Pleuropulmonary Blastoma (PPB) is an extremely uncommon, highly aggressive tumor that arises from either the lungs or pleura. According to Dehner, PPB was classified into three groups: type I (cystic), type II...

    Authors: Hana Hemead, Rania Gaber Aly, Mostafa Kotb and Ahmed Abdelaziz
    Citation: BMC Cancer 2024 24:1268
    Content type: Research Published on:

  10. Immune checkpoint inhibitor (ICI) therapy activates the immune system to recognize and eliminate cancer cells that have escaped surveillance. This study aimed to compare the treatment outcome of advanced and r...

    Authors: Lan Feng, Qun Shi, Shujuan Wang, Ye Zhao, Haiyan Wu, Lei Wei, Qing Hao, Zhaojun Cui, Lin Wang, Jing Zhang, Dan Zhang, Xinxin Zhan and Jingwen Jiang
    Citation: BMC Cancer 2024 24:1267
    Content type: Research Published on:

  11. Mutations in the TP53 tumor suppressor gene are well-established drivers of colorectal cancer (CRC) development. However, data on the prevalence of TP53 variants and their association with consensus molecular sub...

    Authors: Augustin Nzitakera, Delphine Uwamariya, Hisami Kato, Jean Bosco Surwumwe, André Mbonigaba, Ella Larissa Ndoricyimpaye, Schifra Uwamungu, Felix Manirakiza, Marie Claire Ndayisaba, Gervais Ntakirutimana, Benoit Seminega, Vincent Dusabejambo, Eric Rutaganda, Placide Kamali, François Ngabonziza, Rei Ishikawa…
    Citation: BMC Cancer 2024 24:1266
    Content type: Research Published on:

  12. This study aims to investigate how the impact of preoperative sarcopenia and inflammatory markers for laryngeal cancer patients and develop a new scoring system to predict their prognosis.

    Authors: Yizheng Zhang, Zhiyong Meng, Ming Lu, Shenjiong Ruan, Jiao Zhou, Mingchen Zhang, Yanjun Huang, Kehui Chen, Xinyuan Luo, Cheng-ke Xie and Chaohui Zheng
    Citation: BMC Cancer 2024 24:1265
    Content type: Research Published on:

  13. Understanding the factors that contribute to variability in breast cancer-related lymphedema (BCRL) is an important first step in developing targeted interventions to improve quality of life in breast cancer p...

    Authors: Ling Wang, Meixin Zhen, Lulu Liao, Hui Li, Huang Yan, James A. Wiley, Qing Lu, Xuemei Chen, Jun Yv and Boni Ding
    Citation: BMC Cancer 2024 24:1264
    Content type: Research Published on:

  15. Breast cancer brain metastasis (BCBM) is associated with poor survival outcomes and reduced quality of life. The Graded Prognostic Assessment (GPA) score model serves as a well-established tool for predicting ...

    Authors: Yan Wang, Hangcheng Xu, Qiang Sa, Li Li, Yiqun Han, Yun Wu, Yiran Zhou, Binghe Xu and Jiayu Wang
    Citation: BMC Cancer 2024 24:1262
    Content type: Research Published on:

  17. Multimodal two-stage hepatectomy (mTSH) is used in patients with bilobar colorectal liver metastases (CRLM) that cannot be treated with one surgical procedure due to insufficient future liver remnant. Interval...

    Authors: Nathanael Raschzok, Simon Moosburner, Moritz Blank, Felix Krenzien, Georg Lurje, Wenzel Schöning, Igor M. Sauer, Johann Pratschke, Dominik P. Modest and Annika Kurreck
    Citation: BMC Cancer 2024 24:1260
    Content type: Systematic Review Published on:

  18. Dedifferentiated liposarcoma of the extremities (DDL-E) is rare in comparison to that of the retroperitoneum. Its clinical features and surgical principle for resection margins at the dedifferentiated and the ...

    Authors: Jay Hoon Park, Sung Eun Kim, Wanlim Kim, Youngsung Kim, June Hyuk Kim, Sung Wook Seo, Han-Soo Kim, Shinn Kim and Ilkyu Han
    Citation: BMC Cancer 2024 24:1259
    Content type: Research Published on:

  19. The increasing problems of drug and radiotherapy resistance in cervical cancer underscores the need for novel methods for its management. Reports indicate that the expression of MPC1 may be associated with the...

    Authors: Miao Li, Tianhan Xu, Rui Yang, Xiaoyun Wang, Jiawen Zhang and Sufang Wu
    Citation: BMC Cancer 2024 24:1258
    Content type: Research Published on:

  20. Though several nomograms have been established to predict the survival probability of patients with small-cell lung cancer (SCLC), none involved enough variables. This study aimed to construct a novel prognost...

    Authors: Qing Hou, Yu Liang, Ningning Yao, Jianting Liu, Xin Cao, Shuangping Zhang, Lijuan Wei, Bochen Sun, Peixin Feng, Wenjuan Zhang and Jianzhong Cao
    Citation: BMC Cancer 2024 24:1257
    Content type: Research Published on:

  21. Cancer staging is essential in determining patients’ prognoses and designing the appropriate treatment strategy. American Joint Committee on Cancer has released the latest version of the staging system for ton...

    Authors: Maedeh Ghorbanpour, Samaneh Salarvand, Sahar Salarvand, Fatemeh Shahsavari, Mohammad Shirkhoda, Pouyan Amini Shakib and Reza Ghalehtaki
    Citation: BMC Cancer 2024 24:1256
    Content type: Research Published on:

  22. Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and B-cell ALL (B-ALL) is the most common subtype. The understanding of ALL has advanced significantly in recent years due to genomic seq...

    Authors: Ariadne da Rocha Figueiredo, Thayana da Conceição Barbosa, Mariana Emerenciano and Marcelo Gerardin Poirot Land
    Citation: BMC Cancer 2024 24:1255
    Content type: Research Published on:

  23. Radiotherapy is a crucial treatment modality for pelvic cancers, but uncertainties persist in defining the clinical target volume (CTV) for the inguinal lymphatic drainage region. Suboptimal CTV delineation ma...

    Authors: Jia-Li Han, Yan-Ge Qi, Jia-Ling Liu, Xia Yan, Wan-Chun Zhang, Ling Yuan, Xin-Zhong Hao, Jian-Bo Song and Si-Jin Li
    Citation: BMC Cancer 2024 24:1254
    Content type: Research Published on:

  24. Cervical cancer (CC) is a common cancer among women, often treated with Doxorubicin (Doxo). Research is underway to explore the use of oncolytic virus (OV) therapy as a means to improve drug efficacy and enhan...

    Authors: Aezam Rasekhi Kazeruni, Nahid Babaei, Hadi Esmaeili Gouvarchin Ghaleh, Abbas Doosti and Mahdieh Farzanehpour
    Citation: BMC Cancer 2024 24:1253
    Content type: Research Published on:

  25. Gliomas are the highly aggressive brain tumor and also the most devastating human tumors. The latent TGF binding proteins (LTBP) had been found to be involved in malignant biological process and could be used ...

    Authors: Lun Gao, Rui Zhang, Wenbin Zhang, Yanfang Lan, Xiangpan Li, Qiang Cai and Junhui Liu
    Citation: BMC Cancer 2024 24:1252
    Content type: Research Published on:

  26. Today, the prognostic tools available at the time of diagnosis in colorectal cancer (CRC) are limited. Better prognostic tools are a prerequisite for personalised treatment.

    Authors: Siv Stakset Brenne, Poul Henning Madsen, Inge Søkilde Pedersen, Kristian Hveem, Frank Skorpen, Henrik Bygum Krarup, Athanasios Xanthoulis and Eivor Alette Laugsand
    Citation: BMC Cancer 2024 24:1251
    Content type: Research Published on:

  27. With the ongoing prevalence of the emerging variant and global vaccination efforts, the optimal surgical timing for patients with resectable lung cancer in the Omicron-dominant period requires further investig...

    Authors: Ziyun Shen, Zhihua Huang, Tieyuan Zhu, Jing Zhang, Meixin Teng, Yang Qing, Shiqi Hu, Yang Li, Yanzheng Xiong, Jie Shen, Yiwen Huang, Lele Zhang, Huansha Yu, Jian Chen, Dongchun Ma, Qing Geng…
    Citation: BMC Cancer 2024 24:1250
    Content type: Research Published on:

  28. Immune checkpoint inhibitors (ICIs) have shown encouraging treatment efficacy for upper gastrointestinal cancers (UGICs). However, durable clinical responses only existed in a minority of patients. We evaluate...

    Authors: Puxiu Wang, Ping Chen, Weiting Yang, Wenhan Yang, Wenqi Liu, Song Yue and Qiuhua Luo
    Citation: BMC Cancer 2024 24:1249
    Content type: Research Published on:

  29. Locally advanced rectal cancer (LARC) poses unique challenges in treatment, with current neoadjuvant chemoradiotherapy (NA-CRT) showing limitations. The CapeOX regimen emerges as a potential less aggressive ne...

    Authors: Tianan Guo, Kai Liu, Yang Guo, Huan Zhang, Zhonglin Zhu, Dan Huang, Sanjun Cai, Tong Tong, Xiaoyan Zhou and Ye Xu
    Citation: BMC Cancer 2024 24:1248
    Content type: Research Published on:

  30. Neoadjuvant chemoradiotherapy followed by total mesorectal excision is a standard treatment for locally advanced rectal cancer. Mismatch repair-deficient locally advanced rectal cancer (LARC) was highly sensit...

    Authors: Cheng Cai, Xia Zhang, Xiaonan Sun, Huogang Wang, Engeng Chen, Li Chen, Benxing Gu, Jianping Wang, Xuefeng Huang, Weifeng Lao, Xiaowei Wang, Min Chen, Shubo Ding, Jinlin Du and Zhangfa Song
    Citation: BMC Cancer 2024 24:1247
    Content type: Study Protocol Published on:

  31. Although associations have been reported linking pretreatment thrombocytosis to cancer survival outcomes, the validity and strength of existing observational evidence have been contested. This study aimed to c...

    Authors: Chi Shu, Xiran Wang, Changtao Li, Jun Huang, Xuan Xie, Hong Li, Jichun Zhao, Ziqiang Wang, Yazhou He and Yanhong Zhou
    Citation: BMC Cancer 2024 24:1246
    Content type: Systematic Review Published on:

  32. Effective management of adverse events is required to maintain sufficient imatinib dosing when treating patients with gastrointestinal stromal tumors (GISTs). Skin rash is a common adverse event of imatinib, w...

    Authors: Sejin Kim, Hyung-Don Kim, Eo Jin Kim, Min-Hee Ryu and Yoon-Koo Kang
    Citation: BMC Cancer 2024 24:1245
    Content type: Research Published on:

  33. As frontline cells, the precise recruitment of neutrophils is crucial for resolving inflammation and maintaining the homeostasis of the organism. Increasing evidence suggests the pivotal role of neutrophil che...

    Authors: Yunxi Yang, Jun Yang, Linbin Li, Yiming Shao, Lu Liu and Bingwei Sun
    Citation: BMC Cancer 2024 24:1244
    Content type: Research Published on:

  34. Breast cancer is the most commonly diagnosed cancer worldwide. Although major treatments represented by chemotherapy have shown effectiveness at the initial period, recurrence and metastasis still occur later ...

    Authors: Yawei Zhao, Meihui He, Lianzhi Cui, Min Zhang, Tianyu Zhao, Xuehan Yang, Yang Xu, Jianhua Dong, Kan He, Hansi Zhang and Li Chen
    Citation: BMC Cancer 2024 24:1243
    Content type: Research Published on:

  36. The benefit of postoperative adjuvant transcatheter arterial chemoembolization (pTACE) for patients with hepatocellular carcinoma (HCC), especially those with Child-Pugh (CP) B, remains controversial. This stu...

    Authors: Zhen-Yu Gao, Li-Ming Jin, Zheng-Kang Fang, Fang-Qiang Wei, Wen-Feng Lu, Xiao-Kun Huang, Cheng-Fei Du, Kai-Di Wang, Jian Cheng, Guo-Liang Shen, Dong-Sheng Huang, Jun-Wei Liu, Cheng-Wu Zhang and Lei Liang
    Citation: BMC Cancer 2024 24:1241
    Content type: Research Published on:

  38. The advantages of en bloc resection of bladder tumors (ERBT) over transurethral resection of bladder tumors (TURBT) in terms of patient prognosis are not yet clear, and there are some technical limitations. We...

    Authors: Zhipeng Yao, Yang Li, Yuhong Ding, Yaxin Hou, Junyi Hu, Zhenghao Liu, Pengjie Shi, Henglong Hu, Fan Li, Jia Hu, Wen Song, Xiaodong Song, Ke Chen, Lilong Liu and Zheng Liu
    Citation: BMC Cancer 2024 24:1239
    Content type: Research Published on:

  39. The study aims to emphasize the clinical importance of the Deep Inspiration Breath Hold (DIBH) technique by quantifying its dosimetric advantages over Free Breathing (FB) in reducing radiation exposure to the ...

    Authors: Zhuocheng Li, Chenxi Jian, Yuanyuan Li, Zhenyu Pan, Guozi Yang and Xingru Sun
    Citation: BMC Cancer 2024 24:1238
    Content type: Systematic Review Published on:

  40. Anlotinib, an oral multitarget tyrosine kinase inhibitor, has shown the ability to inhibit tumor angiogenesis. This study aimed to assess the effectiveness and safety of anlotinib plus docetaxel, epirubicin, a...

    Authors: Kuojun Ren, Shuhan Wang, Tingbo Ye, Zhengzhi Zhu, Shikai Hong, Shengying Wang and Jianjun Liu
    Citation: BMC Cancer 2024 24:1237
    Content type: Research Published on:

  41. Aldo-keto reductase family 1 member C3 (AKR1C3) is a radioresistance gene in esophageal cancer. This study aimed to investigate the signaling pathways that mediate the regulatory role of AKR1C3 in the radiores...

    Authors: Wei Xiong, Ya Xie, Dong Wang, Xiaozhi Huang, Xiaohui Hao, Jianming Liu, Xiaohui Liu, Xiaobin Gu, Shaoqian Sun, Yufeng Li and Jingwu Li
    Citation: BMC Cancer 2024 24:1236
    Content type: Research Published on:

  43. Results from studies investigating the association between ultra-processed foods (UPFs) and breast cancer are scarce and, in some cases, contradictory. Therefore, we aimed to evaluate the association between t...

    Authors: Mehran Nouri, Fatemeh Mansouri, Fatemeh Jafari, Maryam Ranjbar Zahedani, Saba Jalali, Zeinab Heidari, Zainab Shateri and Bahram Rashidkhani
    Citation: BMC Cancer 2024 24:1234
    Content type: Research Published on:

  45. There is limited research on the clinicopathological characteristics of combined hepatocellular-cholangiocarcinoma (cHCC-CCA) currently. The aim of this study is to summerize the clinicopathological factors an...

    Authors: Yue Li, Du He, Zi-Jian Lu, Xia-Fei Gu, Xiao-Yu Liu, Min Chen, Yin-Xia Tu, Yu Zhou, Gemma Owen, Xian Zhang and Dan Jiang
    Citation: BMC Cancer 2024 24:1232
    Content type: Research Published on:

  46. The characteristics of a tumor are largely determined by its interaction with the surrounding micro-environment (TME). TME consists of both cellular and non-cellular components. Cancer-associated fibroblasts (...

    Authors: Apoorva Abikar, Mohammad Mehaboob Subhani Mustafa, Radhika Rajiv Athalye, Namratha Nadig, Ninad Tamboli, Vinod Babu, Ramaiah Keshavamurthy and Prathibha Ranganathan
    Citation: BMC Cancer 2024 24:1231
    Content type: Research Published on:

  47. Radiotherapy has both immunostimulant and immunosuppressive effects, particularly in radiation-induced lymphopenia. Proton therapy has demonstrated potential in mitigating this lymphopenia, yet the mechanisms ...

    Authors: Juliette Thariat, Thao-Nguyen Pham, Julie Coupey, Benedicte Clarisse, Jean-Michel Grellard, Nathalie Rousseau, Mathieu Césaire and Samuel Valable
    Citation: BMC Cancer 2024 24:1230
    Content type: Study Protocol Published on:

  48. To evaluate the diagnostic efficacy of a deep learning (DL) model based on PET/CT images for distinguishing and predicting various pathological subtypes of invasive lung adenocarcinoma.

    Authors: Dongbo Wu, Yingci Li, Mingyan Zhou, Feifei Gong and Jiankun Li
    Citation: BMC Cancer 2024 24:1229
    Content type: Research Published on:

  49. In locally advanced, operable esophageal squamous cell carcinoma (ESCC), neoadjuvant immunochemotherapy (nICT) has shown results that are somewhat comparable to those of standard neoadjuvant chemoradiotherapy ...

    Authors: Yi Wang, Ke Ma, Huan Zhang, Lei Wu, Li Liu, Yehan Zhou, Lin Peng, Qifeng Wang and Xiang Zhuang
    Citation: BMC Cancer 2024 24:1228
    Content type: Research Published on:

  50. In recent years, the addition of cetuximab to chemotherapy has improved treatment outcomes for patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). In this study, we present th...

    Authors: Muh-Hwa Yang, Tien-Hua Chen, Hung-Ming Wang, Jason Chia-Hsun Hsieh, Huai-Cheng Huang, Meng-Che Hsieh, Chia-Jui Yen, Shang-Yin Wu, Chun-Hung Hua, Ming-Yu Lien, Yi-Fang Chang, Hui-Ching Wang, Chih-Yen Chien, Tai-Lin Huang, Hsueh-Ju Lu, Jin-Ching Lin…
    Citation: BMC Cancer 2024 24:1227
    Content type: Research Published on:

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