Skip to main content

Advertisement

Articles

Page 1 of 213

  1. Glioblastoma multiform (GBM), a malignant brain tumour, has a very often poor prognosis. The therapeutic approach is represented by surgery followed by radiotherapy and chemotherapy. Hypoxia is a factor that c...

    Authors: Vincenzo Gangemi, Chiara Mignogna, Giusy Guzzi, Angelo Lavano, Salvatore Bongarzone, Giuseppe Lucio Cascini and Umberto Sabatini

    Citation: BMC Cancer 2019 19:1197

    Content type: Case report

    Published on:

  2. NF1(Neurofibromatosis type 1) is an autosomal dominant genetic disorder. Patients with NF1 have an increased risk of developing benign or malignant tumours, such as gastrointestinal stromal tumours (GISTs). Ho...

    Authors: Liang Shang, Zhen Fang, Jin Liu, Fengying Du, Haiyan Jing, Yali Xu, Kangdi Dong, Xiaoman Zhang, Hao Wu, Changqing Jing and Leping Li

    Citation: BMC Cancer 2019 19:1196

    Content type: Case report

    Published on:

  3. To discover biomarker panels that could distinguish cancers (BC and RCC) from healthy controls (HCs) and bladder cancers (BC) from renal cell carcinoma (RCC), regardless of whether the patients have haematuria...

    Authors: Zhan Wang, Xiaoyan Liu, Xiang Liu, Haidan Sun, Zhengguang Guo, Guoyang Zheng, Yushi Zhang and Wei Sun

    Citation: BMC Cancer 2019 19:1195

    Content type: Research article

    Published on:

  4. Brain metastasis (BM) is a rare event in ovarian cancer patients. The current prognostic scores that have been used for other tumors do not account for specific characteristics of ovarian cancer, such as plati...

    Authors: Alexandre André Balieiro Anastácio da Costa, Elizabeth Santana dos Santos, Deborah Porto Cotrim, Natasha Carvalho Pandolfi, Marcelle Goldner Cesca, Henrique Mantoan, Solange Moraes Sanches, Adriana Regina Gonçalves Ribeiro, Louise de Brot, Graziele Bonvolim, Paulo Issamu Sanematsu, Ronaldo Pereira de Souza, Joyce Maria Lisboa Maya, Fabrício de Souza Castro, João Paulo da Nogueira Silveira Lima, Michael Jenwel Chen…

    Citation: BMC Cancer 2019 19:1194

    Content type: Research article

    Published on:

  5. Immune checkpoint inhibitors (ICIs) have achieved unprecedented success in cancer treatment over the past decade. The application of ICIs hasled to the discovery of various types of immune-related adverse even...

    Authors: Yuan Liu, Zhi Liu, Xuejun Zeng, Chunmei Bai, Lin Chen, Songbai Lin and Xinlun Tian

    Citation: BMC Cancer 2019 19:1193

    Content type: Case report

    Published on:

  6. Hepatic stellate cells (HSCs) have a key role in fibrogenesis and in the filtrates of the hepatocellular carcinoma (HCC) stroma, in which they are remodeled and play a critical role in HCC progression. However...

    Authors: Xia Liao, Yang Bu, Fan Chang, Fengan Jia, Ge Song, Xuelian Xiao, Mei Zhang, Pengbo Ning and Qingan Jia

    Citation: BMC Cancer 2019 19:1192

    Content type: Research article

    Published on:

  7. Cholangiocarcinoma is a rapidly fatal cancer entity with a median survival of less than one year. In contrast to many other malignancies, no substantial therapeutic breakthrough has been made in the past few d...

    Authors: Thomas Albrecht, Melina Rausch, Stephanie Rössler, Michael Albrecht, Jana Dorothea Braun, Veronika Geissler, Arianeb Mehrabi, Monika Nadja Vogel, Anita Pathil-Warth, Gunhild Mechtersheimer, Marcus Renner, Christian Rupp, Karl Heinz Weiss, Elena Busch, Bruno Köhler, Christoph Springfeld…

    Citation: BMC Cancer 2019 19:1191

    Content type: Research article

    Published on:

  8. Hepatocellular carcinoma (HCC) is an aggressive solid tumor. HCC occurred at younger and elder ages were considered driven by different oncogenic mechanisms, and they demonstrated distinct clinical courses.

    Authors: Puo-Hsien Le, Chia-Jung Kuo, Yi-Chung Hsieh, Tsung-Hsing Chen, Chih-Lang Lin, Chau-Ting Yeh and Kung-Hao Liang

    Citation: BMC Cancer 2019 19:1190

    Content type: Research article

    Published on:

  9. Utilization of RNA sequencing methods to measure gene expression from archival formalin-fixed paraffin-embedded (FFPE) tumor samples in translational research and clinical trials requires reliable interpretati...

    Authors: Michal Marczyk, Chunxiao Fu, Rosanna Lau, Lili Du, Alexander J. Trevarton, Bruno V. Sinn, Rebekah E. Gould, Lajos Pusztai, Christos Hatzis and W. Fraser Symmans

    Citation: BMC Cancer 2019 19:1189

    Content type: Research article

    Published on:

  10. An extremely rare condition, radiation-induced angiosarcoma is characterized by a poor prognosis, high recurrence rate and lack of effective treatment. Herein, we present a case report of a 48-year-old female ...

    Authors: Jieshan Guan, Zhijie Luo, Zhiwei Xiao, Yubin Xie and Lizhu Lin

    Citation: BMC Cancer 2019 19:1188

    Content type: Case report

    Published on:

  11. Precise staging is indispensable to select the appropriate treatment strategy for gastric cancer (GC); however, the diagnostic accuracy of conventional modalities needs to be improved. This study investigated ...

    Authors: Toshiyuki Kosuga, Tomoki Konishi, Takeshi Kubota, Katsutoshi Shoda, Hirotaka Konishi, Atsushi Shiozaki, Kazuma Okamoto, Hitoshi Fujiwara, Michihiro Kudou, Tomohiro Arita, Ryo Morimura, Yasutoshi Murayama, Yoshiaki Kuriu, Hisashi Ikoma, Masayoshi Nakanishi and Eigo Otsuji

    Citation: BMC Cancer 2019 19:1187

    Content type: Research article

    Published on:

  12. Currently, clinical studies on the prognosis of prostate cancer (PC) taking aspirin were developing, but the precise mechanism of aspirin on tumor cells was still unclear. In addition, the conclusion that aspi...

    Authors: Jiatong Zhou, Shuai Xia, Tao Li and Ranlu Liu

    Citation: BMC Cancer 2019 19:1186

    Content type: Research article

    Published on:

  13. Several multicenter randomized controlled trials comparing laparoscopy and conventional open surgery for colon cancer have demonstrated that laparoscopic approach achieved the same oncological results while im...

    Authors: Gilles Manceau, Antoine Brouquet, Pascal Chaibi, Guillaume Passot, Olivier Bouché, Murielle Mathonnet, Jean-Marc Regimbeau, Rea Lo Dico, Jérémie H. Lefèvre, Frédérique Peschaud, Olivier Facy, Enrico Volpin, Elie Chouillard, Laura Beyert-Berjot, Marc Verny, Mehdi Karoui…

    Citation: BMC Cancer 2019 19:1185

    Content type: Study protocol

    Published on:

  14. The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative per-...

    Authors: Tone Hoel Lende, Marie Austdal, Tone Frost Bathen, Anne Elin Varhaugvik, Ivar Skaland, Einar Gudlaugsson, Nina G. Egeland, Siri Lunde, Lars A. Akslen, Kristin Jonsdottir, Emiel A. M. Janssen, Håvard Søiland and Jan P. A. Baak

    Citation: BMC Cancer 2019 19:1183

    Content type: Research article

    Published on:

  15. Excess body weight and sub-optimal lifestyle are modifiable causes of breast cancer and other diseases. There is little evidence that behaviour change is possible within screening programmes and whether this i...

    Authors: Michelle Harvie, Mary Pegington, David French, Grace Cooper, Sarah McDiarmid, Anthony Howell, Louise Donnelly, Helen Ruane, Katharine Sellers, Philip Foden and D. Gareth Evans

    Citation: BMC Cancer 2019 19:1089

    Content type: Research article

    Published on:

  16. To determine safety and efficacy of radiofrequency ablation (RFA) for local treatment of lung metastases of renal cell carcinoma (RCC), sequenced or combined with systemic treatments.

    Authors: Alexis Gonnet, Laura Salabert, Guilhem Roubaud, Vittorio Catena, Véronique Brouste, Xavier Buy, Marine Gross Goupil, Alain Ravaud and Jean Palussière

    Citation: BMC Cancer 2019 19:1182

    Content type: Research article

    Published on:

  17. While colorectal cancer (CRC) patients with localized disease have a favorable prognosis, the five-year-survival rate in patients with distant spread is still below 15%. Hence, a detailed understanding of the ...

    Authors: Sarah Weber, Sebastian E. Koschade, Christopher M. Hoffmann, Taronish D. Dubash, Klara M. Giessler, Sebastian M. Dieter, Friederike Herbst, Hanno Glimm and Claudia R. Ball

    Citation: BMC Cancer 2019 19:1181

    Content type: Research article

    Published on:

  18. Interleukin-6 (IL-6) is commonly highly secreted in the breast cancer (BrCA) microenvironment and implicated in disease development. In this study, we aimed to determine the role of the IL-6/pSTAT3/HIC1 axis i...

    Authors: Xueqing Sun, Qing Qu, Yimin Lao, Mi Zhang, Xiaoling Yin, Huiqin Zhu, Ying Wang, Jie Yang, Jing Yi and Mingang Hao

    Citation: BMC Cancer 2019 19:1180

    Content type: Research article

    Published on:

  19. Some historic breakthroughs have been made in immunotherapy of advanced cancer. However, there is still little research on immunotherapy in prostate cancer. We explored the relationship between immune cell inf...

    Authors: Xin Rui, Siliang Shao, Li Wang and Jiangyong Leng

    Citation: BMC Cancer 2019 19:1179

    Content type: Research article

    Published on:

  20. Previous studies have suggested that lymphoma survivors commonly display altered Health-Related Quality of Life (HRQoL). Because these were predominantly cross-sectional studies, the dynamic of events as well ...

    Authors: Gisèle Compaci, Cécile Conte, Lucie Oberic, Loïc Ysebaert, Guy Laurent and Fabien Despas

    Citation: BMC Cancer 2019 19:1178

    Content type: Research article

    Published on:

  21. Following publication of the original article [1], the authors reported an omission in the affiliations.

    Authors: Shereen El-Mashed, Tracey R. O’Donovan, Elaine W. Kay, Ayat R. Abdallah, Mary-Clare Cathcart, Jacintha O’Sullivan, Anthony O’Grady, John Reynolds, Seamus O’Reilly, Gerald C. O’Sullivan and Sharon L. McKenna

    Citation: BMC Cancer 2019 19:1177

    Content type: Correction

    Published on:

    The original article was published in BMC Cancer 2015 15:582

  22. Deciphering the meaning of the human DNA is an outstanding goal which would revolutionize medicine and our way for treating diseases. In recent years, non-coding RNAs have attracted much attention and shown to...

    Authors: Johannes Smolander, Alexey Stupnikov, Galina Glazko, Matthias Dehmer and Frank Emmert-Streib

    Citation: BMC Cancer 2019 19:1176

    Content type: Research Article

    Published on:

  23. Pancreatic ductal adenocarcinoma (PDAC) is considered as one of the most aggressive cancers lacking efficient early detection biomarkers. Circulating miRNAs are now being considered to have potency to be used ...

    Authors: Bishnupriya Chhatriya, Moumita Mukherjee, Sukanta Ray, Piyali Sarkar, Shatakshee Chatterjee, Debashis Nath, Kshaunish Das and Srikanta Goswami

    Citation: BMC Cancer 2019 19:1175

    Content type: Research article

    Published on:

  24. The prognoses of head and neck squamous cell carcinoma (HNSCC) and esophageal squamous cell carcinoma (ESCC) are poor, especially when both tumors occur at the same time. We examined the clonal relatedness of ...

    Authors: Somkiat Sunpaweravong, Sacarin Bunbanjerdsuk, Tanjitti Pongrujikorn, Chaiwat Naktang, Patrapim Sunpaweravong, Anupong Nitiruangjaras, Tanadech Dechaphankul and Natini Jinawath

    Citation: BMC Cancer 2019 19:1174

    Content type: Research article

    Published on:

  25. Locally advanced breast cancer often undergoes neoadjuvant chemotherapy (NAC), which allows in vivo evaluation of the therapeutic response. The determination of the pathological complete response (pCR) is one ...

    Authors: Wilson Eduardo Furlan Matos Alves, Murilo Bonatelli, Rozany Dufloth, Lígia Maria Kerr, Guilherme Freire Angotti Carrara, Ricardo Filipe Alves da Costa, Cristovam Scapulatempo-Neto, Daniel Tiezzi, René Aloísio da Costa Vieira and Céline Pinheiro

    Citation: BMC Cancer 2019 19:1173

    Content type: Research article

    Published on:

  26. In pediatric sarcomas, outcomes of established therapies still remain poor, especially due to high-grade resistances to chemotherapeutic compounds. Taking novel biological approaches into account, virotherapy ...

    Authors: Chihab Klose, Susanne Berchtold, Marina Schmidt, Julia Beil, Irina Smirnow, Sascha Venturelli, Markus Burkard, Rupert Handgretinger and Ulrich M. Lauer

    Citation: BMC Cancer 2019 19:1172

    Content type: Research article

    Published on:

  27. Luminal B cancers show much worse outcomes compared to luminal A. This present study aims to screen key lncRNAs and mRNAs correlated with luminal-B breast cancer.

    Authors: Cheng-Liang Yuan, Xiang-Mei Jiang, Ying Yi, Jian-Fei E, Nai-Dan Zhang, Xue Luo, Ning Zou, Wei Wei and Ying-Ying Liu

    Citation: BMC Cancer 2019 19:1171

    Content type: Research article

    Published on:

  28. Cisplatin is a potent chemotherapeutic agent used to treat a variety of solid tumors. One of the major side effects of cisplatin is dose-limiting nephrotoxicity. We recently demonstrated that the renal uptake ...

    Authors: Satoshi Shoji, Michihiro Hosojima, Hideyuki Kabasawa, Rie Kondo, Satoru Miura, Satoshi Watanabe, Nobumasa Aoki, Ryohei Kaseda, Shoji Kuwahara, Naohito Tanabe, Yoshiaki Hirayama, Ichiei Narita, Toshiaki Kikuchi, Hiroshi Kagamu and Akihiko Saito

    Citation: BMC Cancer 2019 19:1170

    Content type: Research article

    Published on:

  29. Urokinase plasminogen activator (uPA) is an extracellular matrix-degrading protease that is involved in the invasiveness and progression of cancer. There is good evidence that uPA expression is a clinically re...

    Authors: Ming-Chao Tsai, Yi-Hao Yen, Kuo-Chin Chang, Chao-Hung Hung, Chien-Hung Chen, Ming-Tsung Lin and Tsung-Hui Hu

    Citation: BMC Cancer 2019 19:1169

    Content type: Research article

    Published on:

  30. Adult Ewing sarcoma (ES) is a rare disease, the optimal treatment model is unknown. This study aimed to retrospectively analyze treatment-related prognostic factors of nonspinal ES in Chinese adults.

    Authors: Jianjun Zhang, Yujing Huang, Yuanjue Sun, Aina He, Yan Zhou, Haiyan Hu, Yang Yao and Zan Shen

    Citation: BMC Cancer 2019 19:1168

    Content type: Research article

    Published on:

  31. Circulating tumor cells (CTCs) are associated with breast cancer prognosis. Research is limited regarding the role of circulating cancer stem-like cells (cCSCs) considering the treatment response and survival ...

    Authors: Chun-Hui Lee, Jason Chia-Hsun Hsieh, Tyler Min-Hsien Wu, Ting-Shiuan Yeh, Hung-Ming Wang, Yung-Chan Lin, Jen-Shi Chen, Chia-Lin Lee, Wen-Kuan Huang, Tsung-Min Hung, Tzu-Tsen Yen, Sheng-Chieh Chan, Wen-Chi Chou, Feng-Che Kuan, Ching-Chih Hu and Pei-Hung Chang

    Citation: BMC Cancer 2019 19:1167

    Content type: Research article

    Published on:

  32. Lung cancer (LC) is one of the leading causes of death worldwide, which highlights the urgent need for better therapies. Peroxisome proliferator-activated nuclear receptor alpha (PPARα), known as a key nuclear...

    Authors: Lujin Wu, Wei Wang, Meiyan Dai, Huihui Li, Chen Chen and Daowen Wang

    Citation: BMC Cancer 2019 19:1166

    Content type: Research article

    Published on:

  33. Adrenocortical carcinoma (ACC) is a rare malignant endocrine tumour. Due to a high tumour recurrence rate, the post-operative overall survival (OS) and disease-free survival (DFS) of ACCs is limited. Our resea...

    Authors: Jiayu Liang, Zhihong Liu, Xin Wei, Liang Zhou, Yongquan Tang, Chuan Zhou, Kan Wu, Fuxun Zhang, Fan Zhang, Yiping Lu and Yuchun Zhu

    Citation: BMC Cancer 2019 19:1165

    Content type: Research article

    Published on:

  34. Following publication of the original article [1], the authors reported the following error is the article

    Authors: Shuangmei Ye, Xing Hao, Ting Zhou, Mingfu Wu, Juncheng Wei, Yongjun Wang, Li Zhou, Xuefeng Jiang, Li Ji, Yin Chen, Lanying You, Yiqun Zhang, Gang Xu, Jianfeng Zhou, Ding Ma and Shixuan Wang

    Citation: BMC Cancer 2019 19:1164

    Content type: Correction

    Published on:

    The original article was published in BMC Cancer 2010 10:611

  35. Patients with metastatic spinal cord compression (MSCC) and favorable survival prognoses can benefit from radiation doses greater than 30Gy in 10 fractions in terms of improved local progression-free survival ...

    Authors: Dirk Rades, Olfred Hansen, Lars Henrik Jensen, Liesa Dziggel, Christian Staackmann, Claudia Doemer, Jon Cacicedo, Antonio J. Conde-Moreno, Barbara Segedin, Raquel Ciervide-Jurio, Carmen Rubio-Rodriguez, Luis A. Perez-Romasanta, Ana Alvarez-Gracia, Kristopher Dennis, Carlos Ferrer-Albiach, Arturo Navarro-Martin…

    Citation: BMC Cancer 2019 19:1163

    Content type: Study protocol

    Published on:

  36. To compare the efficacy and safety between conventional transarterial chemoembolization (cTACE) and drug-eluting beads TACE (DEB-TACE) in patients with infiltrative hepatocellular carcinoma (iHCC).

    Authors: Zi-shu Zhang, Hui-zhou Li, Cong Ma and Yu-dong Xiao

    Citation: BMC Cancer 2019 19:1162

    Content type: Research article

    Published on:

  37. Syndecan-1 (SDC-1) is a crucial membrane proteoglycan, which is confirmed to participate in several tumor cell biological processes. However, the biological significance of SDC-1 in colorectal carcinoma is not...

    Authors: Shaojun Wang, Xiaofei Zhang, Guimei Wang, Bin Cao, Hong Yang, Lipeng Jin, Mingjuan Cui and Yongjun Mao

    Citation: BMC Cancer 2019 19:1160

    Content type: Research article

    Published on:

  38. Breast cancer is one of the most commonly diagnosed cancers in women, with high morbidity and mortality. Tumor metastasis is implicated in most breast cancer deaths; thus, inhibiting metastasis may provide a t...

    Authors: Liyi Huang, Haidan Lin, Qing Chen, Lehua Yu and Dingqun Bai

    Citation: BMC Cancer 2019 19:1159

    Content type: Research article

    Published on:

  39. Camptothecin (CPT) and its derivatives are currently used as second- or third-line treatment for patients with endocrine-resistant breast cancer (BC). These drugs convert nuclear enzyme DNA topoisomerase I (TO...

    Authors: Cinzia Tesauro, Anne Katrine Simonsen, Marie Bech Andersen, Kamilla Wandsoe Petersen, Emil Laust Kristoffersen, Line Algreen, Noriko Yokoyama Hansen, Anne Bech Andersen, Ann Katrine Jakobsen, Magnus Stougaard, Pavel Gromov, Birgitta R. Knudsen and Irina Gromova

    Citation: BMC Cancer 2019 19:1158

    Content type: Research article

    Published on:

  40. Personalized therapy for bone metastases should consider the patients’ remaining lifespan. Estimation of survival can be facilitated with scoring tools. A new tool was developed, specifically designed to estim...

    Authors: Dirk Rades, Rapha Haus, Steven E. Schild and Stefan Janssen

    Citation: BMC Cancer 2019 19:1156

    Content type: Research article

    Published on:

  41. Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor. Although lymph node metastasis has been reported, it is still considered benign. No malignant transformation has been reported. This is the first...

    Authors: Xiao Teng and Xiaodong Teng

    Citation: BMC Cancer 2019 19:1154

    Content type: Case report

    Published on:

  42. Half of cancer cases occur in patients aged 70 and above. Majority of older patients are eligible for chemotherapy but evidence for treating this population is sparse and severe toxicities affect more than hal...

    Authors: Zara Steinmeyer, Stéphane Gérard, Thomas Filleron, Stéphanie Lozano, Delphine Brechemier, Gabor Abellan Van Kan, Loic Mourey, Laurence Cristol-Dalstein, Laure De Decker, Yves Rolland and Laurent Balardy

    Citation: BMC Cancer 2019 19:1153

    Content type: Study protocol

    Published on:

  43. Conventional cystoscopy can detect advanced stages of bladder cancer; however, it has limitations to detect bladder cancer at the early stages. Fluorocoxib A, a rhodamine-conjugated analog of indomethacin, is ...

    Authors: Jennifer Bourn, Kusum Rathore, Robert Donnell, Wesley White, Md. Jashim Uddin, Lawrence Marnett and Maria Cekanova

    Citation: BMC Cancer 2019 19:1152

    Content type: Research article

    Published on:

  44. Chemotherapy-induced peripheral neuropathy (CIPN) is common among cancer patients treated with neurotoxic chemotherapy agents. Better knowledge on symptom clusters of CIPN may help improve symptom management i...

    Authors: Mian Wang, Hui Lin Cheng, Violeta Lopez, Raghav Sundar, Janelle Yorke and Alex Molassiotis

    Citation: BMC Cancer 2019 19:1151

    Content type: Research article

    Published on:

  45. Myeloid sarcoma (MS), also known as chloroma, is an extramedullary manifestation of malignant primitive myeloid cells. Previously, only small studies investigated clinical and imaging features of MS. The purpo...

    Authors: Hans-Jonas Meyer, Wolfram Pönisch, Stefan Andreas Schmidt, Susanne Wienbeck, Friederike Braulke, Dominik Schramm and Alexey Surov

    Citation: BMC Cancer 2019 19:1150

    Content type: Research article

    Published on:

  46. Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is...

    Authors: Pierre R. Bourque, Marcos Loreto Sampaio, Jodi Warman-Chardon, Sam Samaan and Carlos Torres

    Citation: BMC Cancer 2019 19:1149

    Content type: Case report

    Published on:

  47. The advent of the immunomodulatory imide drugs (IMiDs) lenalidomide and thalidomide for the treatment of patients with plasma cell myeloma (PCM), has contributed to more than a doubling of the overall survival...

    Authors: Ryan B. Sinit, Dick G. Hwang, Prakash Vishnu, Jess F. Peterson and David M. Aboulafia

    Citation: BMC Cancer 2019 19:1147

    Content type: Case report

    Published on:

Featured videos

View featured videos from across the BMC-series journals