Skip to main content

Articles

Page 1 of 227

  1. Clear cell renal cell carcinoma (ccRCC), the most aggressive renal cancer, is characterized by early lymph node metastases and bad prognosis. Most therapies targeting advanced or metastatic ccRCC are based, as...

    Authors: Marcela García, Maria Belen Palma, Jerome Verine, Santiago Miriuka, Ana M. Inda, Ana L. Errecalde, François Desgrandchamps, Edgardo D. Carosella and Diana Tronik-Le Roux

    Citation: BMC Cancer 2020 20:624

    Content type: Research article

    Published on:

  2. The epidemiological features of Waldenström macroglobulinemia (WM) have seldom been investigated at a national level, particularly in East Asia. The goal of our study is to present the incidence, prevalence, m...

    Authors: Seri Jeong, Seom Gim Kong, Da Jung Kim, Sangjin Lee and Ho Sup Lee

    Citation: BMC Cancer 2020 20:623

    Content type: Research article

    Published on:

  3. Patients with a metastatic breast cancer suffer from a deteriorated health-related quality of life and numerous symptoms such as pain, severe fatigue and a decrease of their physical fitness. As the feasibilit...

    Authors: Lidia Delrieu, Amélie Anota, Olivier Trédan, Damien Freyssenet, Aurélia Maire, Brice Canada, Baptiste Fournier, Olivia Febvey-Combes, Frank Pilleul, Amine Bouhamama, Christophe Caux, Florence Joly, Béatrice Fervers, Vincent Pialoux, David Pérol and Olivia Pérol

    Citation: BMC Cancer 2020 20:622

    Content type: Study protocol

    Published on:

  4. Gastric cancer is the fifth most common cancer worldwide. Along with environmental factors, such as Helicobacter pylori (H. pylori) infection, genetic changes play important roles in gastric tumor formations. miR...

    Authors: Laleh Ebrahimi Ghahnavieh, Hossein Tabatabaeian, Zhaleh Ebrahimi Ghahnavieh, Mohammad Amin Honardoost, Mansoureh Azadeh, Mohamad Moazeni Bistgani and Kamran Ghaedi

    Citation: BMC Cancer 2020 20:621

    Content type: Research article

    Published on:

  5. Several studies have investigated the associations between the podocalyxin-like protein (PODXL) expression quantity or locations and cancers survival, but the results were far from conclusive. Therefore, we pr...

    Authors: Siying He, Wenjie Du, Menglan Li, Ming Yan and Fang Zheng

    Citation: BMC Cancer 2020 20:620

    Content type: Research article

    Published on:

  6. We assessed the mechanism of hematopoietic stem cell (HSC) mobilization using etoposide with granulocyte-colony stimulating factor (G-CSF), and determined how this mechanism differs from that induced by cyclop...

    Authors: Ka-Won Kang, Seung-Jin Lee, Ji Hye Kim, Byung-Hyun Lee, Seok Jin Kim, Yong Park and Byung Soo Kim

    Citation: BMC Cancer 2020 20:619

    Content type: Research article

    Published on:

  7. Despite an improvement of prognosis in breast and colon cancer, the outcome of the metastatic disease is still severe. Microevolution of cancer cells often leads to drug resistance and tumor-recurrence. To tar...

    Authors: Jérôme Ruhnau, Jonas Parczyk, Kerstin Danker, Britta Eickholt and Andreas Klein

    Citation: BMC Cancer 2020 20:617

    Content type: Research article

    Published on:

  8. There is already evidence that the faecal immunochemical test (FIT) is a useful tool for the diagnosis of colorectal cancer (CRC) that helps to identify symptomatic patients requiring early colonoscopy. Althou...

    Authors: María Angeles Gutierrez-Stampa, Vanessa Aguilar, Cristina Sarasqueta, Joaquín Cubiella, Isabel Portillo and Luis Bujanda

    Citation: BMC Cancer 2020 20:616

    Content type: Research article

    Published on:

  9. Breast cancer is a global health problem – it is the most common malignancy among women. Triple negative breast cancers (TNBC) account for 10–20% of female breast cancer. Most TNBC cases confer poor prognosis....

    Authors: Tamás Mezei, Melinda Hajdu, Gábor Czigléczki, Gábor Lotz, Judit Kocsis, Janina Kulka and Anna Horváth

    Citation: BMC Cancer 2020 20:615

    Content type: Case report

    Published on:

  10. Microvascular invasion (MVI) is considered to be one of the important prognostic factors that affect postoperative recurrence in patients with hepatocellular carcinoma (HCC) with variable results across their ...

    Authors: Liming Wang, Weihu Wang, Weiqi Rong, Zhuo Li, Fan Wu, Yunhe Liu, Yiling Zheng, Kai Zhang, Tana Siqin, Mei Liu, Bo Chen and Jianxiong Wu

    Citation: BMC Cancer 2020 20:614

    Content type: Research article

    Published on:

  11. Respiratory motion management with breath hold for patients with hepatobiliary cancers remain a challenge in the precise positioning for radiotherapy. We compared different image-guided alignment markers for e...

    Authors: Tzu-Jie Huang, Yun Tien, Jian-Kuen Wu, Wen-Tao Huang and Jason Chia-Hsien Cheng

    Citation: BMC Cancer 2020 20:613

    Content type: Research article

    Published on:

  12. The clonoSEQ® Assay (Adaptive Biotechnologies Corporation, Seattle, USA) identifies and tracks unique disease-associated immunoglobulin (Ig) sequences by next-generation sequencing of IgH, IgK, and IgL rearran...

    Authors: Travers Ching, Megan E. Duncan, Tera Newman-Eerkes, Mollie M. E. McWhorter, Jeffrey M. Tracy, Michelle S. Steen, Ryan P. Brown, Srivatsa Venkatasubbarao, Nicholas K. Akers, Marissa Vignali, Martin E. Moorhead, Drew Watson, Ryan O. Emerson, Tobias P. Mann, B. Melina Cimler, Pamela L. Swatkowski…

    Citation: BMC Cancer 2020 20:612

    Content type: Research article

    Published on:

  13. To explore the clinical value of texture analysis of MR images (multiphase Gd-EOB-DTPA-enhanced MRI and T2 weighted imaging (T2WI) to identify the differentiated degree of hepatocellular carcinoma (HCC).

    Authors: Mengmeng Feng, Mengchao Zhang, Yuanqing Liu, Nan Jiang, Qian Meng, Jia Wang, Ziyun Yao, Wenjuan Gan and Hui Dai

    Citation: BMC Cancer 2020 20:611

    Content type: Research article

    Published on:

  14. Feasibility testing of a simultaneous sparing approach of hippocampus, hypothalamus and pituitary gland in patients undergoing whole-brain radiotherapy (WBRT) with and without a concomitant boost to metastatic...

    Authors: P. Mehta, S. Janssen, F. B. Fahlbusch, S. M. Schmid, J. Gebauer, F. Cremers, C. Ziemann, M. Tartz and D. Rades

    Citation: BMC Cancer 2020 20:610

    Content type: Research article

    Published on:

  15. Chemotherapy induced cardio-toxicity has been recognized as a serious side effect since the first introduction to anthracyclines (ANT). Cardio-toxicity among patients with breast cancer is well studied but the...

    Authors: Sivan Shamai, Zach Rozenbaum, Ofer Merimsky, Matthew Derakhshesh, Yonatan Moshkovits, Joshua Arnold, Yan Topilsky, Yaron Arbel and Michal Laufer-Perl

    Citation: BMC Cancer 2020 20:609

    Content type: Research article

    Published on:

  16. Considering that the knowledge of adenocarcinoma in villous adenoma of the colorectum is limited to several case reports, we designed a study to investigate independent prognostic factors and developed nomogra...

    Authors: Chao-Tao Tang, Ling Zeng, Jing Yang, Chunyan Zeng and Youxiang Chen

    Citation: BMC Cancer 2020 20:608

    Content type: Research article

    Published on:

  17. Small hepatocellular carcinoma (sHCC) is a special subtype of HCC with the maximum tumor diameter ≤ 3 cm and excellent long-term outcomes. Surgical resection or radiofrequency ablation provides the greatest ch...

    Authors: Yi-hong Ling, Jie-wei Chen, Shi-hong Wen, Chao-yun Huang, Peng Li, Liang-he Lu, Jie Mei, Shao-hua Li, Wei Wei, Mu-yan Cai and Rong-ping Guo

    Citation: BMC Cancer 2020 20:607

    Content type: Research article

    Published on:

  18. Cancer testis (CT) antigens are promising targets for cancer immunotherapies such as cancer vaccines and genetically modified adoptive T cell therapy. In this study, we evaluated the expression of three CT ant...

    Authors: Mikiya Ishihara, Shinichi Kageyama, Yoshihiro Miyahara, Takeshi Ishikawa, Shugo Ueda, Norihito Soga, Hiroaki Naota, Katsumi Mukai, Naozumi Harada, Hiroaki Ikeda and Hiroshi Shiku

    Citation: BMC Cancer 2020 20:606

    Content type: Research article

    Published on:

  19. Little is known about the prevalence and incidence in low and middle-income countries (LMICs) of secondary lymphedema due to cancer. The purpose of the study is to estimate the prevalence and incidence in LMIC...

    Authors: Eric Torgbenu, Tim Luckett, Mark A. Buhagiar, Sungwon Chang and Jane L. Phillips

    Citation: BMC Cancer 2020 20:604

    Content type: Research article

    Published on:

  20. Modulated electro-hyperthermia (mEHT) is a form of hyperthermia used in cancer treatment. mEHT has demonstrated the ability to activate host immunity by inducing the release of heat shock proteins, triggering ...

    Authors: I-Ming Kuo, Jih-Jong Lee, Yu-Shan Wang, Hsin-Chien Chiang, Cheng-Chung Huang, Pei-Jong Hsieh, Winston Han, Chiao-Hsu Ke, Albert T. C. Liao and Chen-Si Lin

    Citation: BMC Cancer 2020 20:603

    Content type: Research article

    Published on:

  21. Esophageal squamous cell carcinoma (ESCC) is a common malignant carcinoma of digestive system with high mortality. RAB, member RAS oncogene family like 6 (RABL6), a member of the RAS subfamily, has been reported ...

    Authors: Yanfen Feng, Shumei Yan, Yuhua Huang, Qitao Huang, Fang Wang and Yiyan Lei

    Citation: BMC Cancer 2020 20:602

    Content type: Research article

    Published on:

  22. Since body mass index (BMI) is a convincing risk factor for breast cancer, it is speculated to be associated with lymph node metastasis. However, epidemiological studies are inconclusive. Therefore, this study...

    Authors: Junyi Wang, Yaning Cai, Fangfang Yu, Zhiguang Ping and Li Liu

    Citation: BMC Cancer 2020 20:601

    Content type: Research article

    Published on:

  23. Colorectal cancer (CRC) is a multifactorial disease resulting from both genetic predisposition and environmental factors including the gut microbiota (GM), but deciphering the influence of genetic variants, en...

    Authors: Jacob E. Moskowitz, Anthony G. Doran, Zhentian Lei, Susheel B. Busi, Marcia L. Hart, Craig L. Franklin, Lloyd W. Sumner, Thomas M. Keane and James M. Amos-Landgraf

    Citation: BMC Cancer 2020 20:600

    Content type: Research article

    Published on:

  24. Cost-effectiveness is a pivotal consideration for clinical decision making of high-tech cancer treatment in developing countries. Intensity-modulated proton radiation therapy (IMPT, the advanced form of proton...

    Authors: Guo Li, Bo Qiu, Yi-Xiang Huang, Jerome Doyen, Pierre-Yves Bondiau, Karen Benezery, Yun-Fei Xia and Chao-Nan Qian

    Citation: BMC Cancer 2020 20:599

    Content type: Research article

    Published on:

  25. Lymph node metastasis is more likely in early-stage breast cancer with lower tumor-infiltrating lymphocyte (TIL) density. Therefore, we investigated the correlation between TILs and lymph node metastasis in cT...

    Authors: Koji Takada, Shinichiro Kashiwagi, Yuka Asano, Wataru Goto, Rika Kouhashi, Akimichi Yabumoto, Tamami Morisaki, Masatsune Shibutani, Tsutomu Takashima, Hisakazu Fujita, Kosei Hirakawa and Masaichi Ohira

    Citation: BMC Cancer 2020 20:598

    Content type: Research article

    Published on:

  26. A major cause of disease-related death in nasopharyngeal carcinoma (NPC) is the development of distant metastasis (DM) despite combination chemoradiotherapy treatment. We previously identified and validated a ...

    Authors: Pierre-Antoine Bissey, Mona Teng, Jacqueline H. Law, Wei Shi, Jeff P. Bruce, Valentin Petit, Sai W. Tsao, Kenneth W. Yip and Fei-Fei Liu

    Citation: BMC Cancer 2020 20:597

    Content type: Research article

    Published on:

  27. Soft-tissue metastasis (STM) is a relatively rare, but not exceptional, manifestation of lung cancer. The purpose of this study was to evaluate the imaging features of STM from lung cancer using fluorine-18 fl...

    Authors: Tingting Xu, Xinyi Zhang, Shumao Zhang, Chunfeng Liu, Wenhui Fu, Chengrun Zeng and Yue Chen

    Citation: BMC Cancer 2020 20:596

    Content type: Research article

    Published on:

  28. Unlike other breast cancer subtypes that may be treated with a variety of hormonal or targeted therapies, there is a need to identify new, effective targets for triple-negative breast cancer (TNBC). It has rec...

    Authors: Gina Sizemore, Sarah McLaughlin, Mackenzie Newman, Kathleen Brundage, Amanda Ammer, Karen Martin, Elena Pugacheva, James Coad, Malcolm D. Mattes and Han-Gang Yu

    Citation: BMC Cancer 2020 20:595

    Content type: Research article

    Published on:

  29. Patients with cancer have an increased risk of malnutrition which is associated with poor outcome. The Mini Nutritional Assessment (MNA®) is often used in older patients with cancer but its relation to outcome...

    Authors: G. Torbahn, T. Strauss, C. C. Sieber, E. Kiesswetter and D. Volkert

    Citation: BMC Cancer 2020 20:594

    Content type: Research article

    Published on:

  30. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Qi Wang, Zixiang Wu, Tianwei Zhan, Shuai Fang, Sai Zhang, Gang Shen and Ming Wu

    Citation: BMC Cancer 2020 20:593

    Content type: Correction

    Published on:

    The original article was published in BMC Cancer 2019 19:500

  31. Metastatic colorectal cancer (CRC) continues to be a major health problem, and current treatments are primarily for disease control and palliation of symptoms. In this study, we developed a precision medicine ...

    Authors: Erdem Altunel, Roham S. Roghani, Kai-Yuan Chen, So Young Kim, Shannon McCall, Kathryn E. Ware, Xiling Shen, Jason A. Somarelli and David S. Hsu

    Citation: BMC Cancer 2020 20:592

    Content type: Research article

    Published on:

  32. The prognosis of patients with progressive or recurrent high-grade gliomas (HGGs) after surgery remains poor. Iodine-125 brachytherapy is emerging as a salvage method for the treatment of gliomas. This study a...

    Authors: Congxiao Wang, Shifeng Liu, Lijing Peng, Kaixian Zhang, Wei Li, Hao Zhang, Ying Luan, Peishun Li and Xiaokun Hu

    Citation: BMC Cancer 2020 20:591

    Content type: Research article

    Published on:

  33. Ex vivo drug screening refers to the out-of-body assessment of drug efficacy in patient derived vital tumor cells. The purpose of these methods is to enable functional testing of patient specific efficacy of a...

    Authors: Rami Mäkelä, Antti Arjonen, Ville Härmä, Nina Rintanen, Lauri Paasonen, Tobias Paprotka, Kerstin Rönsch, Teijo Kuopio, Juha Kononen and Juha K. Rantala

    Citation: BMC Cancer 2020 20:590

    Content type: Research article

    Published on:

  34. We examined the association between obesity and prostate cancer based on both body mass index (BMI) and waist circumference (WC) using the National Health Insurance System (NHIS) database for the entire male p...

    Authors: Jin Bong Choi, Jun-Pyo Myong, Yunhee Lee, Inah Kim, Jung Ho Kim, Sung-Hoo Hong and U-Syn Ha

    Citation: BMC Cancer 2020 20:589

    Content type: Research article

    Published on:

  35. Prostate Cancer (PCa) is the second most common cancer in men where advancements have been made for early detection using imaging techniques, however these are limited by lesion size. Immune surveillance has e...

    Authors: Ali Mehdi, David Cheishvili, Ani Arakelian, Tarek A. Bismar, Moshe Szyf and Shafaat A. Rabbani

    Citation: BMC Cancer 2020 20:588

    Content type: Research article

    Published on:

  36. Gastric cancer is one of the deadliest cancer entities worldwide. While surgery is the only curative treatment option in early tumors, for locally advanced and metastatic patients further therapeutic targets a...

    Authors: Jan Rehkaemper, Michael Korenkov, Alexander Quaas, Josef Rueschoff, Aylin Pamuk, Thomas Zander, Axel M. Hillmer, Reinhard Buettner, Arnulf Heinrich Hoelscher, Christiane Josephine Bruns, Heike Loeser, Hakan Alakus and Birgid Schoemig-Markiefka

    Citation: BMC Cancer 2020 20:587

    Content type: Research article

    Published on:

  37. HOXA family genes were crucial transcription factors involving cell proliferation and apoptosis. While few studies have focused on HOXA10 in AML. We aimed to investigate the prognostic significance of HOXA10.

    Authors: Chao Guo, Qian-qian Ju, Chun-xia Zhang, Ming Gong, Zhen-ling Li and Ya-yue Gao

    Citation: BMC Cancer 2020 20:586

    Content type: Research article

    Published on:

  38. Previous studies have shown that branched-chain amino acid transferase 1 (BCAT1) is associated with tumour progression in triple-negative breast cancer (TNBC). Furthermore, CD133 has emerged as a novel cancer ...

    Authors: Yu Song, Bin Zhao, Yali Xu, Xinyu Ren, Yan Lin, Liangrui Zhou and Qiang Sun

    Citation: BMC Cancer 2020 20:584

    Content type: Research article

    Published on:

  39. P53 pathway inactivation plays an important role in the process of breast cancer tumorigenesis. Post-translational protein modification abnormalities have been confirmed to be an important mechanism underlying...

    Authors: Qian Pu, Yan-rong Lv, Ke Dong, Wen-wen Geng and Hai-dong Gao

    Citation: BMC Cancer 2020 20:583

    Content type: Research article

    Published on:

  40. As a natural alkaloid product isolated from Sophora alopecuroides. L, Sophoridine reshapes gastric cancer immune microenvironment via inhibiting chemotaxis and M2 polarization of tumor-associated macrophages (TAM...

    Authors: Zhiyang Peng, Qing Guan, Jianfei Luo, Wenhong Deng, Jiasheng Liu, Ruicheng Yan and Weixing Wang

    Citation: BMC Cancer 2020 20:582

    Content type: Research article

    Published on:

  41. Esophageal carcinoma (EC) is the seventh-most prevalent tumor in the world, which is still one of the primary causes of tumor-related death. Identifying noteworthy biomarkers for EC is particularly significant...

    Authors: Yiding Li, Guiling Wu, Wanli Yang, Xiaoqian Wang, Lili Duan, Liaoran Niu, Yujie Zhang, Jinqiang Liu, Liu Hong and Daiming Fan

    Citation: BMC Cancer 2020 20:581

    Content type: Research article

    Published on:

  42. Non-small cell lung cancer (NSCLC) remains a huge health burden for human health and life worldwide. Our study here was to illuminate the relevance of microRNA-130a-5p (miR-130a-5p) on growth and epithelial me...

    Authors: Fang Ma, Yangchun Xie, Yiyu Lei, Zengshuyu Kuang and Xianling Liu

    Citation: BMC Cancer 2020 20:580

    Content type: Research article

    Published on:

  43. To explore the diagnostic value of radiomics features of preoperative computed tomography (CT) for triple negative breast cancer (TNBC) for better treatment of patients with breast cancer.

    Authors: Qingliang Feng, Qiang Hu, Yan Liu, Tao Yang and Ziyi Yin

    Citation: BMC Cancer 2020 20:579

    Content type: Research article

    Published on:

  44. This pilot trial aimed to investigate whether modified short-term fasting (mSTF) reduces the incidence of chemotherapy-induced toxicities and whether an initial ketogenic diet (KD) as fasting supportive diet r...

    Authors: Stefanie Zorn, Janine Ehret, Rebecca Schäuble, Beate Rautenberg, Gabriele Ihorst, Hartmut Bertz, Paul Urbain and Anna Raynor

    Citation: BMC Cancer 2020 20:578

    Content type: Research article

    Published on:

  45. Qualitative research on cancer patients’ survivor-identity and lived experiences in low- and middle-income countries is scarce. Our study aimed at exploring the concept and experience of survivorship for Mexic...

    Authors: Felicia Marie Knaul, Svetlana V. Doubova, María Cecilia Gonzalez Robledo, Alessandra Durstine, Gabriela Sophia Pages, Felicia Casanova and Hector Arreola-Ornelas

    Citation: BMC Cancer 2020 20:577

    Content type: Research article

    Published on:

  46. Omega-3 polyunsaturated fatty acids (PUFAs) were proposed to have potential effects against inflammation and cancer. However, results from epidemiology studies remain inconsistent. We aimed to explore the asso...

    Authors: Peiqin Li, Boer Shan, Keyu Jia, Fan Hu, Ying Xiao, Jusheng Zheng, Yu-Tang Gao, Huaying Wang and Ying Gao

    Citation: BMC Cancer 2020 20:576

    Content type: Research article

    Published on:

Featured videos

View featured videos from across the BMC-series journals