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  1. Following publication of the original article [1], the authors reported an error in Fig 5 of this article, graphs presenting FCM and immunofluorescent for CD4T, CD8T and NK cell of the Control Groups (LL2, LL2...

    Authors: Hongwei Tian, Gang Shi, Guoyou Yang, Junfeng Zhang, Yiming Li, Tao Du, Jianzhou Wang, Fen Xu, Lin Cheng, Xiaomei Zhang, Lei Dai, Xiaolei Chen, Shuang Zhang, Yang Yang, Dechao Yu, Yuquan Wei…

    Citation: BMC Cancer 2020 20:42

    Content type: Correction

    Published on:

    The original article was published in BMC Cancer 2014 14:48

  2. There is increasing recognition that PROs are important in the estimation of the burden of long-term survival among patients with gastric cancer. The study aimed to develop a disease-specific instrument to ass...

    Authors: Xiaojuan Hu, Fen Zhao, Hongmei Yu, Yanhong Luo, Jinchun Liu and Yanbo Zhang

    Citation: BMC Cancer 2020 20:41

    Content type: Research article

    Published on:

  3. This study aimed to explore the heterogeneity of circRNA expression pattern via microarray, and further evaluate the potential of 10 specific circRNAs as diagnostic and prognostic biomarkers in multiple myelom...

    Authors: Fan Zhou, Dongjiao Wang, Wei Wei, Haimin Chen, Haotian Shi, Nian Zhou, Lixia Wu and Rong Peng

    Citation: BMC Cancer 2020 20:40

    Content type: Research article

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  4. Optimal therapy for colorectal carcinoma (CRC), a frequently diagnosed malignancy, does not exist. Some of colicins and microcins, ribosomally synthesized peptides by gramnegative bacteria, have shown signific...

    Authors: Darina Kohoutova, Miroslava Forstlova, Paula Moravkova, Jiri Cyrany, Juraj Bosak, David Smajs, Stanislav Rejchrt and Jan Bures

    Citation: BMC Cancer 2020 20:39

    Content type: Research article

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  5. Pancreatic adenosquamous carcinoma has a poor prognosis, with limited prospective trial data to guide optimal treatment. The potential impact of drug metabolism on the treatment response of patients with pancr...

    Authors: Claire M. Connell, Rebecca Brais, Hayley Whitaker, Sara Upponi, Ian Beh, Jane Risdall, Pippa Corrie, Tobias Janowitz and Duncan I. Jodrell

    Citation: BMC Cancer 2020 20:38

    Content type: Case report

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  6. Intratumoral heterogeneity has an enormous effect on patient treatment and outcome. The purpose of the current study was to establish and validate a nomogram with intratumoral heterogeneity derived from 18F-fluor...

    Authors: Bingxin Gu, Jianping Zhang, Guang Ma, Shaoli Song, Liqun Shi, Yingjian Zhang and Zhongyi Yang

    Citation: BMC Cancer 2020 20:37

    Content type: Research article

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  7. The aim of the present study was to assess the efficacy of concurrent chemoradiotherapy (CRT) or radiotherapy alone (RT-alone) in elderly patients with esophageal squamous cell carcinoma (ESCC).

    Authors: Mingqiu Chen, Xiaohong Liu, Chun Han, Xin Wang, Yidian Zhao, Qingsong Pang, Xinchen Sun, Gaofeng Li, Kaixian Zhang, Ling Li, Xueying Qiao, Yu Lin, Junqiang Chen and Zefen Xiao

    Citation: BMC Cancer 2020 20:36

    Content type: Research article

    Published on:

  8. The prognosis of glioma is poor, despite recent advances in diagnosis and treatment of the disease. It is important to investigate the clinical characteristics and prognostic factors of glioma so as to provide...

    Authors: Jianfeng Liang, Xiaomin Lv, Changyu Lu, Xun Ye, Xiaolin Chen, Jia Fu, Chenghua Luo and Yuanli Zhao

    Citation: BMC Cancer 2020 20:35

    Content type: Research article

    Published on:

  9. Gastric cancer (GC) is a leading cause of cancer death, occurs predominantly in older age, with increasing incidence in young patients. The Cancer Genome Atlas indicates four subtypes for GC among which Epstei...

    Authors: Assaf Moore, Elad Hikri, Tal Goshen-Lago, Tamar Barkan, Sara Morgenstern, Elena Brook, Annett Maderer, Wilfried Roth, Noa Gordon, Hanoch Kashtan, Baruch Brenner, Markus Moehler and Irit Ben Aharon

    Citation: BMC Cancer 2020 20:34

    Content type: Research article

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  10. Matrix metalloproteinase 7 (MMP7), as the smallest member of the matrix metalloproteinase family, has been verified to be implicated in cancer progression, especially metastasis. However, its expression patter...

    Authors: Shuo Yuan, Li-song Lin, Rui-Huan Gan, Li Huang, Xiao-ting Wu, Yong Zhao, Bo-hua Su, Dali Zheng and You-Guang Lu

    Citation: BMC Cancer 2020 20:33

    Content type: Research article

    Published on:

  11. Vasculogenic mimicry (VM), defined as a capability of aggressive tumor Cells to mimic embryonic vasculogenic networks, caused poor prognosis in hepatocellular carcinoma (HCC). Rho kinases (ROCK), p21-activated...

    Authors: Ji-Gang Zhang, He-Ming Zhou, Xue Zhang, Wan Mu, Juan-Ni Hu, Gao-Lin Liu and Qin Li

    Citation: BMC Cancer 2020 20:32

    Content type: Research article

    Published on:

  12. Chemo-resistance in hepatocellular carcinoma (HCC) is a major problem, and acquired drug resistance prevents cancer therapies from achieving complete responses. Molecular targeting therapy presents an opportun...

    Authors: Xia Liao, Ge Song, Zihan Xu, Yang Bu, Fan Chang, Fengan Jia, Xuelian Xiao, Xuejiao Ren, Mei Zhang and Qingan Jia

    Citation: BMC Cancer 2020 20:31

    Content type: Research article

    Published on:

  13. Childhood cancers represent a small proportion of all cancers but are still a major public health problem. The study analysed long-term trends in childhood cancer incidence and survival in Estonia in relation ...

    Authors: Keiu Paapsi, Aleksei Baburin, Sirje Mikkel, Margit Mägi, Kadri Saks and Kaire Innos

    Citation: BMC Cancer 2020 20:30

    Content type: Research article

    Published on:

  14. To evaluate radiomics analysis in neuro-oncologic studies according to a radiomics quality score (RQS) system to find room for improvement in clinical use.

    Authors: Ji Eun Park, Ho Sung Kim, Donghyun Kim, Seo Young Park, Jung Youn Kim, Se Jin Cho and Jeong Hoon Kim

    Citation: BMC Cancer 2020 20:29

    Content type: Research article

    Published on:

  15. Pyroptosis belongs to a novel inflammatory programmed cell death pathway, with the possible prognosis of endometrial cancer related to the terminal protein GSDMD. Hydrogen exerts a biphasic effect on cancer by...

    Authors: Ye Yang, Ping Yin Liu, Wei Bao, Song Jun Chen, Fang Su Wu and Ping Ya Zhu

    Citation: BMC Cancer 2020 20:28

    Content type: Research article

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  16. High grade gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) with a Ki67 proliferation index > 20%, include well-differentiated tumours grade 3 (NET G3) and poorly differentiated (PD) neuroendocrine ...

    Authors: Kirstine Nielsen, Tina Binderup, Seppo W. Langer, Andreas Kjaer, Pauline Knigge, Veronica Grøndahl, Linea Melchior, Birgitte Federspiel and Ulrich Knigge

    Citation: BMC Cancer 2020 20:27

    Content type: Research article

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  17. Combining anti-cancer therapies with orthogonal modes of action, such as direct cytotoxicity and immunostimulatory, hold promise for expanding clinical benefit to patients with metastatic disease. For instance...

    Authors: Qing Wang, Zhijun Wang, Yan Wu and David J. Klinke II

    Citation: BMC Cancer 2020 20:26

    Content type: Research Article

    Published on:

  18. There are many types of therapies for cancer. In these days, immunotherapies, especially immune checkpoint inhibitors, are focused on. Though many types of immune checkpoint inhibitors are there, the differenc...

    Authors: Kazushige Yoshida, Masanori Okamoto, Jun Sasaki, Chika Kuroda, Haruka Ishida, Katsuya Ueda, Hirokazu Ideta, Takayuki Kamanaka, Atsushi Sobajima, Takashi Takizawa, Manabu Tanaka, Kaoru Aoki, Takeshi Uemura, Hiroyuki Kato, Hisao Haniu and Naoto Saito

    Citation: BMC Cancer 2020 20:25

    Content type: Research article

    Published on:

  19. The optimal chemotherapeutics of recurrent disseminated glioblastoma has yet to be determined. We analyzed the efficacy and safety of recombinant human endostatin (rh-ES) combined with temozolomide and irinote...

    Authors: Jing-jing Ge, Cheng Li, Shao-pei Qi, Feng-jun Xue, Zhi-meng Gao, Chun-jiang Yu and Jun-ping Zhang

    Citation: BMC Cancer 2020 20:24

    Content type: Research article

    Published on:

  20. The NEK serine/threonine protein kinases are involved in cell cycle checkpoints, DNA damage repair, and apoptosis. Alterations in these pathways are frequently associated with cell malignant cellular transform...

    Authors: Talita Diniz Melo-Hanchuk, Mariana Bonjiorno Martins, Lucas Leite Cunha, Fernando Augusto Soares, Laura Sterian Ward, José Vassallo and Jörg Kobarg

    Citation: BMC Cancer 2020 20:23

    Content type: Research article

    Published on:

  21. The precise content and frequency of follow-up of patients with colorectal cancer (CRC) is variable and guideline adherence is low. The aim of this study was to assess the view of colorectal surgeons on their ...

    Authors: S. M. Qaderi, N. A. T. Wijffels, A. J. A. Bremers and J. H. W. de Wilt

    Citation: BMC Cancer 2020 20:22

    Content type: Research article

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  22. There is no comprehensive agreement concerning the overall performance of radical resection for T1b gallbladder cancer (GBC). This research focused on addressing whether T1b GBC may spread loco-regionally and ...

    Authors: Kizuki Yuza, Jun Sakata, Pankaj Prasoon, Yuki Hirose, Taku Ohashi, Koji Toge, Kohei Miura, Masayuki Nagahashi, Takashi Kobayashi and Toshifumi Wakai

    Citation: BMC Cancer 2020 20:20

    Content type: Research article

    Published on:

  23. Adjuvant chemotherapy is relatively underused in older patients with colon cancer in Japan, and its age-specific effects on clinical outcomes remain unclear. This study aimed to assess the effect of adjuvant c...

    Authors: Hidetaka Kawamura, Toshitaka Morishima, Akira Sato, Michitaka Honda and Isao Miyashiro

    Citation: BMC Cancer 2020 20:19

    Content type: Research article

    Published on:

  24. We retrospectively compared the prognostic value between the AJCC 8th edition anatomic (AS) and prognostic staging (PS) system for triple negative breast cancer (TNBC) in a cohort from two involved institution...

    Authors: Jiehua He, Julia Y. Tsang, Xiaodan Xu, Jibin Li, Mei Li, Xue Chao, Yuanyuan Xu, Rongzhen Luo, Gary M. Tse and Peng Sun

    Citation: BMC Cancer 2020 20:18

    Content type: Research article

    Published on:

  25. Germ cell tumours (GCTs) represent a highly curable malignity as they respond well to cisplatin (CDDP)-based chemotherapy. Nevertheless, a small proportion of GCT patients relapse or do not respond to therapy....

    Authors: Zuzana Cierna, Vera Miskovska, Jan Roska, Dana Jurkovicova, Lucia Borszekova Pulzova, Zuzana Sestakova, Lenka Hurbanova, Katarina Machalekova, Michal Chovanec, Katarina Rejlekova, Daniela Svetlovska, Katarina Kalavska, Karol Kajo, Pavel Babal, Jozef Mardiak, Thomas A. Ward…

    Citation: BMC Cancer 2020 20:17

    Content type: Research article

    Published on:

  26. Improved, multimodal treatment strategies have been shown to increase cure rates in cancer patients. Those who survive cancer as a child, adolescent or young adult (CAYA), are at a higher risk for therapy-, or...

    Authors: J. Salchow, J. Mann, B. Koch, J. von Grundherr, W. Jensen, S. Elmers, L. A. Straub, E. Vettorazzi, G. Escherich, S. Rutkowski, S. Dwinger, C. Bergelt, M. Sokalska-Duhme, S. Bielack, G. Calaminus, K. Baust…

    Citation: BMC Cancer 2020 20:16

    Content type: Study protocol

    Published on:

  27. Patients with lymphoma are at risk for developing pulmonary opportunistic infections due to immunocompromise. However, clinical reports of concurrent lymphoma and opportunistic infection at presentation are ra...

    Authors: Lianyou Shao, Longxiang Jiang, Siyao Wu, Lihua Yu, Liangxing Wang and Xiaoying Huang

    Citation: BMC Cancer 2020 20:15

    Content type: Case report

    Published on:

  28. Targeted therapies are a standard of care for first-line treatment of Anaplastic lymphoma kinase (ALK)-rearranged non small cell lung cancer (NSCLC). Giving the rapid pace of drug discovery and development in thi...

    Authors: F. Guisier, N. Piton, M. Bellefleur, N. Delberghe, G. Avenel, E. Angot, O. Vittecoq, M. Ould-Slimane, H. Morisse-Pradier, M. Salaun and L. Thiberville

    Citation: BMC Cancer 2020 20:14

    Content type: Case report

    Published on:

  29. Primary angiosarcomas of the right atrium are extremely rare, often resulted in missed diagnosis or misdiagnosis with routine examination tools. These malignant cardiac tumors are highly aggressive with genera...

    Authors: Yi Yu, Qunshan Wang, Jian Sun, Jing Zhao, Suyun Chen and Yigang Li

    Citation: BMC Cancer 2020 20:13

    Content type: Case report

    Published on:

  30. The SWI/SNF complex is an important chromatin remodeler, commonly dysregulated in cancer, with an estimated mutation frequency of 20%. ARID1A is the most frequently mutated subunit gene. Almost nothing is know...

    Authors: Simon Schallenberg, Julian Bork, Ahlem Essakly, Hakan Alakus, Reinhard Buettner, Axel M. Hillmer, Christiane Bruns, Wolfgang Schroeder, Thomas Zander, Heike Loeser, Florian Gebauer and Alexander Quaas

    Citation: BMC Cancer 2020 20:12

    Content type: Research article

    Published on:

  31. We sought to investigate the prognostic value of complete blood count (CBC)-based biomarkers for patients with resectable gastric cancer (GC).

    Authors: Jian-Xian Lin, Jun-Peng Lin, Jian-Wei Xie, Jia-bin Wang, Jun Lu, Qi-Yue Chen, Long-long Cao, Mi Lin, Ruhong Tu, Chao-Hui Zheng, Chang-Ming Huang and Ping Li

    Citation: BMC Cancer 2020 20:11

    Content type: Research article

    Published on:

  32. Surgery is the only way to cure gastric adenocarcinoma (GAC), and chemotherapy is the basic adjuvant management for GAC. A significant prognostic nomogram for predicting the respective disease-specific surviva...

    Authors: Chao-Yang Wang, Jin Yang, Hao Zi, Zhong-Li Zheng, Bing-Hui Li, Yang Wang, Zheng Ge, Guang-Xu Jian, Jun Lyu, Xiao-Dong Li and Xue-Qun Ren

    Citation: BMC Cancer 2020 20:10

    Content type: Research article

    Published on:

  33. There is absence of literature related to cough prevalence and its characteristics in lung cancer patients, with information deriving only from broader symptoms occurrence studies. The aims of this study were ...

    Authors: Amélie Harle, Alex Molassiotis, Oliver Buffin, Jack Burnham, Jaclyn Smith, Janelle Yorke and Fiona H. Blackhall

    Citation: BMC Cancer 2020 20:9

    Content type: Research article

    Published on:

  34. Patients with locally advanced bladder cancer (cT3/4 cN0/N+ cM0) have a poor prognosis despite radical surgical therapy and perioperative chemotherapy. Preliminary data suggest that the combination of radiatio...

    Authors: Sebastian C. Schmid, Florestan J. Koll, Claus Rödel, Philipp Maisch, Andreas Sauter, Franziska Beckert, Anna Seitz, Hubert Kübler, Michael Flentje, Felix Chun, Stephanie E. Combs, Kilian Schiller, Jürgen E. Gschwend and Margitta Retz

    Citation: BMC Cancer 2020 20:8

    Content type: Study protocol

    Published on:

  35. Glioblastomas (GBM) are therapy-resistant tumors with a profoundly immunosuppressive tumor microenvironment. Chemotherapy has shown limited efficacy against GBM. Systemic delivery of chemotherapeutic drugs is ...

    Authors: Julio Enríquez Pérez, Jan Kopecky, Edward Visse, Anna Darabi and Peter Siesjö

    Citation: BMC Cancer 2020 20:7

    Content type: Research article

    Published on:

  36. Hepatocellular carcinoma (HCC) is a major health problem worldwide. However, the popular tumor marker, AFP, lacks sensitivity although its specificity is high. Tissue biopsy is an invasive operation and may in...

    Authors: Wene Wei, Mengshu Liu, Shufang Ning, Jing Wei, Jianhong Zhong, Jilin Li, Zhengmin Cai and Litu Zhang

    Citation: BMC Cancer 2020 20:6

    Content type: Research article

    Published on:

  37. The occurrence of a mediastinal germ cell tumor (GCT) and hematological malignancy in the same patient is very rare. Due to its rarity, there have been only two reports of the concurrent cases undergoing detai...

    Authors: Keiichi Akizuki, Masaaki Sekine, Yasunori Kogure, Takuro Kameda, Kotaro Shide, Junji Koya, Ayako Kamiunten, Yoko Kubuki, Yuki Tahira, Tomonori Hidaka, Takumi Kiwaki, Hiroyuki Tanaka, Yuichiro Sato, Hiroaki Kataoka, Keisuke Kataoka and Kazuya Shimoda

    Citation: BMC Cancer 2020 20:5

    Content type: Research article

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  38. Cell migration and invasion are essential processes for metastatic dissemination of cancer cells. Significant progress has been made in developing new therapies against oncogenic signaling to eliminate cancer ...

    Authors: Pradip Shahi Thakuri, Megha Gupta, Sunil Singh, Ramila Joshi, Eric Glasgow, Alexander Lekan, Seema Agarwal, Gary D. Luker and Hossein Tavana

    Citation: BMC Cancer 2020 20:4

    Content type: Research article

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  39. Ewing sarcoma is a malignancy of primitive cells, possibly of mesenchymal origin. It is probable that genetic perturbations other than EWS-FLI1 cooperate with it to produce the tumor. Sequencing studies identifie...

    Authors: Marc El Beaino, Jiayong Liu, Amanda R. Wasylishen, Rasoul Pourebrahim, Agata Migut, Bryan J. Bessellieu, Ke Huang and Patrick P. Lin

    Citation: BMC Cancer 2020 20:3

    Content type: Research article

    Published on:

  40. Bcl-2 family members play an important role in the development of malignant lymphoma and can induce drug resistance in anticancer treatment. The development of small molecules targeting Bcl-2 family proteins m...

    Authors: Yue-Li Sun, Wen-Qi Jiang, Qiu-Yun Luo, Da-Jun Yang, Yu-Chen Cai, Hui-Qiang Huang and Jian Sun

    Citation: BMC Cancer 2019 20:1

    Content type: Research article

    Published on:

  41. Our aim is to study if mammographic density (MD) prior to neoadjuvant chemotherapy is a predictive factor in accomplishing a pathological complete response (pCR) in neoadjuvant-treated breast cancer patients.

    Authors: Ida Skarping, Daniel Förnvik, Hanna Sartor, Uffe Heide-Jørgensen, Sophia Zackrisson and Signe Borgquist

    Citation: BMC Cancer 2019 19:1272

    Content type: Research article

    Published on:

  42. Endemic Burkitt lymphoma (eBL) is an aggressive B-cell lymphoma, which is a common childhood cancer in areas with intense transmission of Plasmodium falciparum parasites. Early and accurate diagnosis is a prerequ...

    Authors: Cecilia Smith-Togobo, Mette Ø. Pedersen, Steffen G. Jensen, Babatunde Duduyemi, Richard K. Gyasi, Michael F. Ofori, Vivian Paintsil, Lorna Renner, Peter Nørgaard and Lars Hviid

    Citation: BMC Cancer 2019 19:1270

    Content type: Research article

    Published on:

  43. Cell adhesion-mediated drug resistance (CAM-DR) is a major clinical problem that prevents successful treatment of multiple myeloma (MM). In particular, the expression levels of integrin β1 and its sub-cellular...

    Authors: Yuejiao Huang, Xianting Huang, Chun Cheng, Xiaohong Xu, Hong Liu, Xiaojing Yang, Li Yao, Zongmei Ding, Jie Tang, Song He and Yuchan Wang

    Citation: BMC Cancer 2019 19:1269

    Content type: Research article

    Published on:

  44. Ganglioneuromas (GNs) are composed of mature ganglion cells and Schwann cells with a fibrous stroma; GNs are most often observed in children and young adults. The majority of non-cranial GNs are located in the...

    Authors: Chu-Wen Fang, Jyh-Seng Wang, Tony T. Wu and Jen-Tai Lin

    Citation: BMC Cancer 2019 19:1265

    Content type: Case report

    Published on:

  45. Androgen deprivation therapy (ADT) in the treatment of prostate cancer may be associated with an increased risk of thromboembolic disease. The aim of our study was to investigate the association of ADT in the ...

    Authors: Kuang-Ming Liao, Yaw-Bin Huang, Chung-Yu Chen and Chen-Chun Kuo

    Citation: BMC Cancer 2019 19:1263

    Content type: Research article

    Published on:

  46. Nimotuzumab (NTZ) is an anti-EGFR monoclonal antibody. However,the effect of targeted drugs combined with induction therapy in locally advanced nasopharyngeal carcinoma remains unclear. The aim of this study i...

    Authors: Ying Lu, Dagui Chen, Jinhui Liang, Jianquan Gao, Zhanxiong Luo, Rensheng Wang, Wenqi Liu, Changjie Huang, Xuejian Ning, Meilian Liu and Haixin Huang

    Citation: BMC Cancer 2019 19:1262

    Content type: Research article

    Published on:

  47. The principle of loss of iodine uptake and increased glucose metabolism according to dedifferentiation of thyroid cancer is clinically assessed by imaging. Though these biological properties are widely applied...

    Authors: Hoon Young Suh, Hongyoon Choi, Jin Chul Paeng, Gi Jeong Cheon, June-Key Chung and Keon Wook Kang

    Citation: BMC Cancer 2019 19:1260

    Content type: Research article

    Published on:

  48. Following publication of the original article [1], the authors reported the following errors/updates.

    Authors: Maneesh Kumarsing Beeharry, Zheng-Lun Zhu, Wen-Tao Liu, Xue-Xin Yao, Min Yan and Zheng-Gang Zhu

    Citation: BMC Cancer 2019 19:1256

    Content type: Correction

    Published on:

    The original article was published in BMC Cancer 2019 19:932

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