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  1. Textbook outcome (TO) is a composite measure reflecting various aspects of services provided to patients with solid malignancies. We sought to evaluate the importance of various TO components previously propos...

    Authors: L Bobrzynski, K Sędłak, K Rawicz-Pruszyński, P Kolodziejczyk, A Szczepanik, W Polkowski, P Richter and M Sierzega
    Citation: BMC Cancer 2023 23:1199
  2. Due to the high drug resistance of hepatocellular carcinoma (HCC), sorafenib has limited efficacy in the treatment of advanced HCC. Cancer-associated fibroblasts (CAFs) play an important regulatory role in the...

    Authors: Jiali Zhao, En Lin, Zirui Bai, Yingbin Jia, Bo Wang, Yihua Dai, Wenfeng Zhuo, Guifang Zeng, Xialei Liu, Chaonong Cai, Peiping Li, Baojia Zou and Jian Li
    Citation: BMC Cancer 2023 23:1198
  3. A worldwide increased incidence of HM has been marked in recent decades. Therefore, to update epidemiological characteristics of HM in a French West Indies territory, we have performed analysis through Martini...

    Authors: Rémi Houpert, Thierry Almont, Rostom Belahreche, Mamadi Faro, Jennie Okouango, Mylène Vestris, Jonathan Macni, Olivier Pierre-Louis, Christelle Montabord, Murielle Beaubrun-Renard, Naby Soumah, Martial Boisseau, Jacqueline Véronique-Baudin and Clarisse Joachim
    Citation: BMC Cancer 2023 23:1197
  4. Immunotherapy in combination with platinum-etoposide (EP) chemotherapy has been approved as a first-line treatment for extensive-stage small cell lung cancer (ES-SCLC). However, real-world (RW) data regarding ...

    Authors: Yanrong Wang, Lingling Li, Jia Hu, Yan Zhao, Huan Yan, Ming Gao, Xuejiao Yang, Xia Zhang, Junxun Ma and Guanghai Dai
    Citation: BMC Cancer 2023 23:1196
  5. To detect circulating tumor cells (CTCs) in the peripheral blood of patients with tumor, and to analyze the significance of CTC detection in tumor diagnosis and monitoring. In the present study, peripheral blo...

    Authors: Yuanrui Liu, Rong Zhao, Zaichun Xie, Zhiyu Pang, Shengjie Chen, Qian Xu and Zhanfeng Zhang
    Citation: BMC Cancer 2023 23:1195
  6. Tumor-infiltrating lymphocytes (TILs) by routine hematoxylin and eosin staining (H&E-TILs) are a robust prognostic biomarker in various cancers. However, the role of H&E-TILs in esophageal squamous cell carcin...

    Authors: Jifang Zheng, Hejun Zhang, Siya Li, Zhaoxin Kang, Fei Zheng, Qiwei Yao, Xueqing Zhang, Ziyi Wu, Jiezhong Wang, Weimin Fang, Jiancheng Li, Gang Chen, Yuangui Chen and Mingqiu Chen
    Citation: BMC Cancer 2023 23:1193
  7. The current gastric cancer staging system relies on the number of metastatic lymph nodes (MLNs) for nodal stage determination. However, incorporating additional information such as topographic status may help ...

    Authors: Chul-Hyo Jeon, Ki Bum Park, Hayemin Lee, Dong Jin Kim, Ho Seok Seo, Junhyun Lee, Kyung Hwa Jun, Jin Jo Kim and Han Hong Lee
    Citation: BMC Cancer 2023 23:1192
  8. Patients diagnosed with low-risk prostate cancer (PCa) are confronted with a difficult decision regarding whether to undergo definitive treatment or to pursue an active surveillance protocol. This is potential...

    Authors: Alice Guan, Eduardo J. Santiago-Rodríguez, Benjamin I. Chung, Janet K. Shim, Laura Allen, Mei-Chin Kuo, Kathie Lau, Zinnia Loya, James D. Brooks, Iona Cheng, Mindy C. DeRouen, Dominick L. Frosch, Todd Golden, John T. Leppert, Daphne Y. Lichtensztajn, Qian Lu…
    Citation: BMC Cancer 2023 23:1191
  9. Routine clinical staging for hepatocellular carcinoma (HCC) incorporates liver function, general health, and tumor morphology. Further refinement of prognostic assessments and treatment decisions may benefit f...

    Authors: Kong-Ying Lin, Qing-Jing Chen, Shi-Chuan Tang, Zhi-Wen Lin, Jian-Xi Zhang, Si-Ming Zheng, Yun-Tong Li, Xian-Ming Wang, Qiang Lu, Jun Fu, Luo-Bin Guo, Li-Fang Zheng, Peng-Hui You, Meng-Meng Wu, Ke-Can Lin, Wei-Ping Zhou…
    Citation: BMC Cancer 2023 23:1190
  10. Colorectal cancer (CRC) is a leading cause of cancer-related mortality, highlighting an unmet clinical need for more effective therapies. This study aims to evaluate the causal relationship between 4,489 plasm...

    Authors: Yi-Xin Cai, Yi-Qing Wu, Jie Liu, Huanle Pan, Wenhai Deng, Weijian Sun, Congying Xie and Xiu-Feng Huang
    Citation: BMC Cancer 2023 23:1188
  11. Chemoradiation therapy (CRT) followed by surgery is currently the standard of care to treat patients with locally advanced rectal cancer (LARC). CRT reduces local recurrences, but is associated with significan...

    Authors: D. M. Mens, J. M. van Rees, S. M. Wilting and C. Verhoef
    Citation: BMC Cancer 2023 23:1187
  12. Less than half of unselected metastatic cancer patients benefit from the immune checkpoint inhibitor (ICI) therapy. Systemic cancer-related inflammation may influence the efficacy of ICIs and thus, systemic in...

    Authors: Satu Tiainen, Veera Nurmela, Tuomas Selander, Patrik Turunen, Sanna Pasonen-Seppänen, Tiia Kettunen, Outi Kuittinen, Päivi Auvinen and Aino Rönkä
    Citation: BMC Cancer 2023 23:1186
  13. Hepatocellular carcinoma (HCC) is a major health concern, necessitating a deeper understanding of its prognosis and underlying mechanisms. This study aimed to investigate the mechanism and prognostic value of CD8

    Authors: Kejun Liu, Junhao Liu, Xusheng Zhang, Di Liu, Weijie Yao, Yang Bu and Bendong Chen
    Citation: BMC Cancer 2023 23:1185
  14. Up to the present time, there has remained a lack of strong evidence as to whether sentinel lymph node biopsy can replace lymphadenectomy for early endometrial cancer. The traditional surgery for endometrial c...

    Authors: Yanglong Guo, Lu Sun, Xi Chen, Qiang Wen, Zhuyan Shao, Xuedong Tang, XiaoJun Shi, Jinyu Wang, Yingli Zhang and Tao Zhu
    Citation: BMC Cancer 2023 23:1184
  15. Obesity is a risk factor for breast cancer, and women with obesity that develop breast cancer have a worsened prognosis. Within the mammary gland, obesity causes chronic, macrophage-driven inflammation and adi...

    Authors: Genevra Kuziel, Brittney N. Moore, Grace P. Haugstad, Yue Xiong, Abbey E. Williams and Lisa M. Arendt
    Citation: BMC Cancer 2023 23:1183
  16. Patients diagnosed with small cell lung cancer (SCLC) typically experience a poor prognosis, and it is essential to predict overall survival (OS) and stratify patients based on distinct prognostic risks.

    Authors: Ziqian Song, Hengmin Ma, Hao Sun, Qiuxia Li, Yan Liu, Jing Xie, Yukun Feng, Yuwang Shang, Kena Ma, Nan Zhang and Jialin Wang
    Citation: BMC Cancer 2023 23:1182
  17. The predictive biomarkers of immune checkpoint inhibitors (ICIs) in hepatocellular carcinoma (HCC) still need to be further explored. This study aims to establish a new immune prognosis biomarker to predict th...

    Authors: Rujia Zhang, Haoran Zhao, Peng Wang, Zuoming Guo, Chunxun Liu and Zhaowei Qu
    Citation: BMC Cancer 2023 23:1181
  18. Osteosarcoma (OS) is the most common primary malignancy of bone tumors. More and more ARHGAP family genes have been confirmed are to the occurrence, development, and invasion of tumors. However, its significan...

    Authors: Wenda Liu, Kezhou Xia, Di Zheng, Xinghan Huang, Zhun Wei, Zicheng Wei and Weichun Guo
    Citation: BMC Cancer 2023 23:1179
  19. Many patients treated for breast cancer (BC) complain about cognitive difficulties affecting their daily lives. Recently, sleep disturbances and circadian rhythm disruptions have been brought to the fore as po...

    Authors: Clara Elia, Laura de Girolamo, Bénédicte Clarisse, Melvin Galin, Stéphane Rehel, Patrice Clochon, Franck Doidy, Shailendra Segobin, Fausto Viader, Mikaël Naveau, Nicolas Delcroix, Carine Segura-Djezzar, Jean-Michel Grellard, Justine Lequesne, Olivier Etard, Tristan Martin…
    Citation: BMC Cancer 2023 23:1178
  20. Breast cancer (BC) is one of the malignant diseases threatening the life and health of women worldwide. The CYP4B1 gene was abnormally expressed in BC and was associated with the prognosis of BC patients. This st...

    Authors: Yanhai Yin, Liangqian Tong, Zhenling Wan, Yanfang Sui, Fen Li, Qian Huang and Xinhan Zhao
    Citation: BMC Cancer 2023 23:1177
  21. Previous studies on cancer of unknown primary (CUP) mainly focus on treatment and prognosis in western populations and lacked clinical evaluation of different IHC markers, so this study aimed to evaluate chara...

    Authors: Min Ren, Xu Cai, Liqing Jia, Qianming Bai, Xiaoli Zhu, Xichun Hu, Qifeng Wang, Zhiguo Luo and Xiaoyan Zhou
    Citation: BMC Cancer 2023 23:1175
  22. In order to deliver appropriate and timely care planning and minimise avoidable late diagnoses, clinicians need to be aware of which patients are at higher risk of receiving a late cancer diagnosis. We aimed t...

    Authors: Sarah Mills, Peter Donnan, Deans Buchanan and Blair H. Smith
    Citation: BMC Cancer 2023 23:1174
  23. Angiogenesis is an important hallmark of Glioblastoma (GBM) marked by elevated vascular endothelial growth factor-A (VEGF-A) and its receptor 2 (VEGFR-2). As previously reported nimbolide (NBL), trans-chalcone...

    Authors: Anna Senrung, Tanya Tripathi, Joni Yadav, Divya Janjua, Apoorva Chaudhary, Arun Chhokar, Nikita Aggarwal, Udit Joshi, Nidhi Goswami and Alok Chandra Bharti
    Citation: BMC Cancer 2023 23:1173
  24. There is a lack of standard salvage treatment options for recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) that has failed platinum-containing regimens. Breakthroughs in immunotherapy have opened up n...

    Authors: Jian Luo, Wanying Xiao, Fengyang Hua, Yanqing Cao, Dongxia Wang and Xicheng Wang
    Citation: BMC Cancer 2023 23:1172
  25. The aim of the study is to explore the role of preoperative folate receptor-positive circulating tumor cell (FR+CTC) levels in predicting disease-free survival (DFS) and overall survival (OS) in patients with eso...

    Authors: Qiang Zhou, Qiao He, Wenwu He, Chenghao Wang, Guangyuan Liu, Kangning Wang, Haojun Li, Jialong Li, Wenguang Xiao, Qiang Fang, Lin Peng, Yongtao Han, Dongsheng Wang and Xuefeng Leng
    Citation: BMC Cancer 2023 23:1171
  26. Immunoglobulin superfamily 6 (IGSF6) is a novel member of the immunoglobulin superfamily and has been implicated in various diseases. However, the specific role of IGSF6 in the anti-tumor immunity within lung ...

    Authors: Qisi Zheng, Ting Wang, Gechen Jiang, Miao Li, Zhi Zhang, Yuxin Chen and Xinyu Tian
    Citation: BMC Cancer 2023 23:1170
  27. Colorectal cancer (CRC) is one of the most common malignant tumors, influenced by several genetic loci in its clinical phenotypes. The aim of this study was to determine the relationship between the MMP8 gene pol...

    Authors: Shuyong Yu, Jiajia Cheng, Ping Li, Le Tian, Zhuang Chen, Zhaowei Chen, Yongyu Li and Jian Song
    Citation: BMC Cancer 2023 23:1169
  28. Prophylactic irradiation of supraclavicular lymph node drainage areas can improve the regional control rate of lymph node-positive or lymph node-negative disease but a locally-advanced stage breast cancer, and...

    Authors: Li Li, Hongyan Zhang, Linwei Wang, Conghua Xie, Haijun Yu and Yahua Zhong
    Citation: BMC Cancer 2023 23:1168
  29. Some biomarkers collected from routine laboratory tests have shown important value in cancer prognosis. The study aimed to evaluate the prognostic significance of routine laboratory biomarkers in patients with...

    Authors: Rong Cong, Mingyang Li, Wan Xu, Xiaoxin Ma and Shuhe Wang
    Citation: BMC Cancer 2023 23:1167
  30. Paclitaxel and carboplatin is the standard chemotherapy for the treatment of advanced or recurrent endometrial cancer. However, the benefit of adding programmed cell death 1 (PD-1)/programmed death ligand 1 (P...

    Authors: Francisco Cezar Aquino de Moraes, Eric Pasqualotto, Lucca Moreira Lopes, Maria Eduarda Cavalcanti Souza, Anna Luíza Soares de Oliveira Rodrigues, Artur Menegaz de Almeida, Carlos Stecca, Marianne Rodrigues Fernandes and Ney Pereira Carneiro dos Santos
    Citation: BMC Cancer 2023 23:1166
  31. 18F-FDG PET/CT provides precise information about dissemination of lymphoma lesions. Dmax, defined as distance between the two lesions that were farthest apart by PET/CT, was found to be a promising predictor of....

    Authors: Fei Wang, Silu Cui, Luo Lu, Xiaoliang Shao, Feng Yan, Yaqi Liu, Bai He, Jianfeng Wang, Yang Cao, Yanhua Yue, Yuetao Wang and Weiying Gu
    Citation: BMC Cancer 2023 23:1165
  32. Vaginal CO2 laser therapy is a new treatment option for genitourinary syndrome of menopause. Its potential is particularly interesting in breast cancer survivors, where existing treatment options often are insuff...

    Authors: Sine Jacobsen, Marianne Glavind-Kristensen, Anders Bonde Jensen, Axel Forman and Pinar Bor
    Citation: BMC Cancer 2023 23:1164
  33. The NOD-, LRR- and pyrin domain‑containing 3 (NLRP3) inflammasome is a critical component of the innate immune system. It has been known to play an important role in the carcinogenesis and prognosis of breast ...

    Authors: Qian-mei Zhu, Hui-xian Li, Pei-qing Ma, Lin-xin Wu, Tai-hang Wang, Wen-bin Li, Lin Zhang, Xue Yang, Xiangyi Kong, Yu-lin Sun and Tao Yan
    Citation: BMC Cancer 2023 23:1163
  34. CXC chemokine ligand 3 (CXCL3) is a member of CXC-type chemokine family that is identified as a major regulator in immune and inflammation responses. Recently, numerous evidence indicated that CXCL3 is broadly...

    Authors: Yao Cheng, Xinyan Yang, Lichun Liang, Hua Xin, Xinyu Dong, Weidong Li, Jie Li, Xiaoli Guo, Yue Li, Jian He, Chunbin Zhang and Weiqun Wang
    Citation: BMC Cancer 2023 23:1162
  35. Cantharidin (CTD) is the active ingredient of Chinese medicine, which has been traditionally used in multiple cancers treatment, especially in hepatocellular carcinoma (HCC). However, a comprehensive analysis ...

    Authors: Jia Yan, Yu min Gao, Xiu ling Deng, Hai sheng Wang and Gui tao Shi
    Citation: BMC Cancer 2023 23:1161
  36. Composition of the intestinal microbiota has been correlated to therapeutic efficacy of immune checkpoint inhibitors (ICI) in various cancer entities including melanoma. Prediction of the outcome of such thera...

    Authors: Anastasia Tsakmaklis, Fedja Farowski, Rafael Zenner, Till Robin Lesker, Till Strowig, Hans Schlößer, Jonas Lehmann, Michael von Bergwelt-Baildon, Cornelia Mauch, Max Schlaak, Jana Knuever, Viola Schweinsberg, Lucie M. Heinzerling and Maria J. G. T. Vehreschild
    Citation: BMC Cancer 2023 23:1160
  37. As a histone methyltransferase, suppressor of variegation 3–9 homolog 1 (SUV39H1) plays an important role in the occurrence and development of cancer. To explore the mechanism and biological function of SUV39H...

    Authors: Yanping Zhang, Wanwen Lao, Kaming Yang, Xinyi Kong, Yuetong Li, Xin Yu, Xumeng Wang, Yang Liu, Zhenlin Li, Yilin Deng, Shuping Nie, Changlong Bi, Chao Wu and Aixia Zhai
    Citation: BMC Cancer 2023 23:1159
  38. Thymic epithelial tumors (TETs) are the most common primary neoplasms of the anterior mediastinum. Different risk subgroups of TETs have different prognosis and therapeutic strategies, therefore, preoperative ...

    Authors: Rongji Gao, Jian Zhou, Juan Zhang, Jianzhong Zhu, Tiantian Wang and Chengxin Yan
    Citation: BMC Cancer 2023 23:1158
  39. To compare the computed tomography (CT) images of patients with locally advanced gastric cancer (GC) before and after neoadjuvant chemotherapy (NAC) in order to identify CT features that could predict patholog...

    Authors: Chengzhi Wei, Yun He, Ma Luo, Guoming Chen, Runcong Nie, Xiaojiang Chen, Zhiwei Zhou and Yongming Chen
    Citation: BMC Cancer 2023 23:1157
  40. Urachal cancer is similar to gastrointestinal adenocarcinoma in histology, and gastroscopy/colonoscopy is often administered during perioperative evaluation. However, gastroscopy and colonoscopy have correspon...

    Authors: Ming-rui Luo, Tao-nong Cai, Jiang-li Lu, Zhen-hua Liu, Sheng-jie Guo, Zhuo-wei Liu, Kai Yao, Zi-ke Qin and Yun-lin Ye
    Citation: BMC Cancer 2023 23:1156
  41. The increasing prevalence of cancer detection necessitated practical strategies to deliver highly accurate, beneficial, and dependable processed information together with experimental results. We deleted the c...

    Authors: Marzieh Javadi, Hossein Sazegar and Abbas Doosti
    Citation: BMC Cancer 2023 23:1155
  42. Epithelial, connective tissue and immune cells contribute in various ways to the pathophysiology of HPV positive (HPV+) and HPV negative (HPV-) oropharyngeal squamous cell carcinoma (OPSCC). We aimed to invest...

    Authors: Aris I. Giotakis, Annette Runge, József Dudas, Rudolf Glueckert, Timo Gottfried, Volker H. Schartinger, Johanna Klarer, Avneet Randhawa, Eleonora Caimmi and Herbert Riechelmann
    Citation: BMC Cancer 2023 23:1154
  43. Chronic myeloid leukemia (CML) is effectively treated with tyrosine kinase inhibitors (TKIs), targeting the BCR::ABL1 oncoprotein. Still, resistance to therapy, relapse after treatment discontinuation, and sid...

    Authors: Lukas Häselbarth, Sara Gamali, Domenica Saul, Manuela Krumbholz, Romy Böttcher-Loschinski, Martin Böttcher, Deyu Zou, Markus Metzler, Axel Karow and Dimitrios Mougiakakos
    Citation: BMC Cancer 2023 23:1153
  44. Triple-negative breast cancer (TNBC) is a lethal mammary carcinoma subtype that affects females and is associated with a worse prognosis. Chemotherapy is the only conventional therapy available for patients wi...

    Authors: Basant Emad, Amr Ahmed WalyEldeen, Hebatallah Hassan, Marwa Sharaky, Ismail A Abdelhamid, Sherif Abdelaziz Ibrahim and Hanan RH Mohamed
    Citation: BMC Cancer 2023 23:1151
  45. The role of circulating tumor cells (CTCs) in prognosis prediction has been actively studied in hepatocellular carcinoma (HCC) patients. However, their efficiency in accurately predicting early progression rec...

    Authors: Zhan Lu, Hanghang Ni, Xihua Yang, Lihao Tan, Haixiao Zhuang, Yunning Mo, Xingyu Wei, Lunan Qi and Bangde Xiang
    Citation: BMC Cancer 2023 23:1150
  46. To investigate the potential correlation between piwi-like RNA-mediated gene silencing 1 (PIWIL1) polymorphisms and susceptibility to epithelial ovarian cancer (EOC).

    Authors: Shanshan Liu, Yaping Yan, Zhizhong Cui, Haipeng Feng, Fengmei Zhong, Ziguang Liu, Yan Li, Xiang Ou and Wenjuan Li
    Citation: BMC Cancer 2023 23:1149

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