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Retraction Note: Numb inhibits epithelial-mesenchymal transition via RBP-Jκ-dependent Notch1/PTEN/FAK signaling pathway in tongue cancer

The Original Article was published on 25 April 2019

Retraction Note: BMC Cancer 19, 391 (2019)

https://doi.org/10.1186/s12885-019-5605-5

The Editors have retracted this article. After publication, concerns were raised regarding image similarities in the presented figures. Specifically:

  • Figure 2b CAL27 NC and Numb 0h images appear highly similar;

  • Figure 2b SCC-9 Numb 24h  and Fig. 5b SCC-9 RPB-Jk shRNA 0h images appear highly similar (with different brightness);

  • Figure 2b SCC-9 NC 24h and Fig. 5b SCC-9 shNC 24h images appear highly similar (with different brightness);

  • Figure 2b SCC-9 Numb 48h and Fig. 5b SCC-9 RPB-Jk shRNA 48h images appear highly similar (with different brightness);

  • Figure 2d CAL27 Numb and Fig. 5d CAL27 RPB-Jk shRNA images appear highly similar (with rotation).

The authors have provided the raw data for validation. However, the Editors found some inconsistencies in the raw data, and determined them to be insufficient to address the above concerns. The Editors therefore no longer have confidence in the presented data.

The authors have not responded to any correspondence from the publisher about this retraction notice.

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Correspondence to Jin-Yun Li or Zan Li.

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The online version of the original article can be found at https://doi.org/10.1186/s12885-019-5605-5.

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Li, JY., Huang, WX., Zhou, X. et al. Retraction Note: Numb inhibits epithelial-mesenchymal transition via RBP-Jκ-dependent Notch1/PTEN/FAK signaling pathway in tongue cancer. BMC Cancer 24, 512 (2024). https://doi.org/10.1186/s12885-024-12253-2

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  • DOI: https://doi.org/10.1186/s12885-024-12253-2