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  1. The PACIFIC study has demonstrated that the administration of durvalumab following concurrent chemoradiotherapy can significantly improve both overall survival and progression-free survival rates in patients w...

    Authors: Zhenyi Yang, Wen Zhong, Yixuan Luo and Chunli Wu
    Citation: BMC Cancer 2023 23:962
    Content type: Research Published on:

  2. Cervical cancer is a public health problem. It is one of the leading causes of death in women worldwide and the second leading cause of female cancer-related deaths. Cervical cancer screening enables the detec...

    Authors: Tangut Misgun and Dereje Bayissa Demissie
    Citation: BMC Cancer 2023 23:961
    Content type: Research Published on:

  3. The Mitogen-activated protein kinase 1 (MAPK1) has both independent functions of phosphorylating histones as a kinase and directly binding the promoter regions of genes to regulate gene expression as a transcr...

    Authors: Yue Wang, Zheng Guo, Yueli Tian, Liang Cong, Yulu Zheng, Zhiyuan Wu, Guangle Shan, Yao Xia, Yahong Zhu, Xingang Li and Ying Song
    Citation: BMC Cancer 2023 23:959
    Content type: Research Published on:

  4. Prostate cancer is a disease that seriously troubles men. However, there are some inevitable limitations in interventional therapy for prostate cancer patients at present, most of which are caused by low selec...

    Authors: Lan Huang, Buqing Ma, Chong Zhang, Jiaqi Shi, Rui Shen, Erci Zhang, Chenlei Lian, Cuifang Wang and Jieqing Liu
    Citation: BMC Cancer 2023 23:957
    Content type: Research Published on:

  5. MicroRNAs (miRNAs) have been reported to serve as potential biomarkers in bladder cancer and play important roles in cancer progression. This study aimed to investigate the biological role of miR-205-3p in bla...

    Authors: Zou Zhenhai, Cheng Qi, Zhang Shuchao, Wang Zhongqi, Song Xue, Geng Zhijun, Mei Zhijie, Liu Jianmin, Liu Beibei and Guo Yuanyuan
    Citation: BMC Cancer 2023 23:956
    Content type: Research Published on:

  6. The interruption of normal cell cycle execution acts as an important part to the development of leukemia. It was reported that microRNAs (miRNAs) were closely related to tumorigenesis and progression, and thei...

    Authors: Bei Xie, Lei Zhao, Zhewen Zhang, Cunmin Zhou, Ye Tian, Yingying Kang, Jing Chen, Hulai Wei and Linjing Li
    Citation: BMC Cancer 2023 23:955
    Content type: Research Published on:

  8. Small (< 4 cm) clear cell renal cell carcinoma (ccRCC) is the most common type of small renal cancer and its prognosis is poor. However, conventional radiological characteristics obtained by computed tomograph...

    Authors: Yankun Gao, Xia Wang, Xiaoying Zhao, Chao Zhu, Cuiping Li, Jianying Li and Xingwang Wu
    Citation: BMC Cancer 2023 23:953
    Content type: Research Published on:

  9. Mammographic density (MD) is a strong risk factor for breast cancer. We aimed to evaluate the association between MD and breast cancer related risk factors among average-risk women in rural China.

    Authors: Huijiao Yan, Wenhui Ren, Mengmeng Jia, Peng Xue, Zhifang Li, Shaokai Zhang, Lichun He and Youlin Qiao
    Citation: BMC Cancer 2023 23:952
    Content type: Research Published on:

  12. Collagens are the major components of the extracellular matrix (ECM) and are known to contribute to tumor progression and metastasis. There are 28 different types of collagens each with unique functions in mai...

    Authors: Marina Crespo-Bravo, Jeppe Thorlacius-Ussing, Neel I. Nissen, Rasmus S. Pedersen, Mogens K. Boisen, Maria Liljefors, Astrid Z. Johansen, Julia S. Johansen, Morten A. Karsdal and Nicholas Willumsen
    Citation: BMC Cancer 2023 23:949
    Content type: Research Published on:

  13. HER2-positive breast cancer (BC) invasiveness and drug-resistance issue is the critical treatment obstacle recently. We investigated the total and phosphorylated status EZH2 expression in database and BC tissu...

    Authors: Feng Yu, Lili Li, Mengwen Zhang and Shanshan Sun
    Citation: BMC Cancer 2023 23:948
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2023 23:1176

  15. Previous studies reported inconsistent results regarding the association between keratinocyte carcinoma (KC) and exogenous hormone therapy. This study aimed to investigate the association between the use of ex...

    Authors: Lin Li, Baoqiang Pei and Yanyan Feng
    Citation: BMC Cancer 2023 23:946
    Content type: Research Published on:

  16. Glioblastoma (GB) is the most aggressive of all primary brain tumours and due to its highly invasive nature, surgical resection is nearly impossible. Patients typically rely on radiotherapy with concurrent tem...

    Authors: Craig A. Vincent, Itzel Nissen, Soran Dakhel, Andreas Hörnblad and Silvia Remeseiro
    Citation: BMC Cancer 2023 23:945
    Content type: Research Published on:

  17. Pan-immune-inflammation value (PIV) is defined by the neutrophil, platelet, monocyte, and lymphocyte counts and is associated with immune-checkpoint inhibitor (ICI) therapy outcomes in advanced non-small cell ...

    Authors: Yiqun Chen, Lingyan Gong, Pengyang Gu, Yiwen Hua, Yingfang Sun, Songshi Ni, Xiaoyu Zhou and Zhiyuan Tang
    Citation: BMC Cancer 2023 23:944
    Content type: Research Published on:

  18. Nephrectomy, whether in the era of cytokine therapy or targeted therapy, has an important role in the treatment of metastatic renal cell carcinoma. With the advent of immunotherapy, immunotherapy combined with...

    Authors: Hanzhi Dong, Yuan Cao, Yan Jian, Jun Lei, Weimin Zhou, Xiaoling Yu, Xiquan Zhang, Zhiqiang Peng and Zhe Sun
    Citation: BMC Cancer 2023 23:943
    Content type: Research Published on:

  19. Tumor necrosis factor receptor-associated factor 3 (TRAF3) has specific regulatory effects on a wide range of diseases, including tumors. However, the effect and mechanism of TRAF3 on lung adenocarcinoma (LUAD...

    Authors: Wangjia Wang, Shiqi Wang, Min Wang, Yamei Ma, Wanting Hu, Binsha Wu, Chichi Li and Dan Zhang
    Citation: BMC Cancer 2023 23:942
    Content type: Research Published on:

  20. Inflammatory, immune, and nutritional status are key factors in obstructive colorectal cancer (OCRC). This study aims to investigate the value of modified Naples prognostic score (M-NPS) in evaluating OCRC pro...

    Authors: Junnan Gu, Shenghe Deng, Zhenxing Jiang, Fuwei Mao, Yifan Xue, Le Qin, Jianguo Shi, Jia Yang, Huili Li, Jie Yu, Ke Liu, Ke Wu, Yinghao Cao and Kailin Cai
    Citation: BMC Cancer 2023 23:941
    Content type: Research Published on:

  21. This study aimed to identify patients with upper urinary tract urothelial carcinoma (UTUC) having potential Lynch syndrome (pLS) by immunohistochemistry (IHC) of DNA mismatch repair gene-related proteins (MMRP...

    Authors: Kenji Tanabe, Yasukazu Nakanishi, Naoya Okubo, Shunya Matsumoto, Yosuke Umino, Madoka Kataoka, Shugo Yajima, Teruhiko Yoshida, Saori Miyazaki, Takeshi Kuwata, Genichiro Ishii, Reiko Watanabe and Hitoshi Masuda
    Citation: BMC Cancer 2023 23:940
    Content type: Research Published on:

  22. Extracellular vesicles (EVs) hold promise for improving our understanding of radiotherapy response in glioblastoma due to their role in intercellular communication within the tumour microenvironment (TME). How...

    Authors: Stephen David Robinson, Mark Samuels, William Jones, Duncan Gilbert, Giles Critchley and Georgios Giamas
    Citation: BMC Cancer 2023 23:939
    Content type: Research Published on:

  23. Egypt has the greatest prevalence of hepatitis C worldwide according to the WHO reports, accounting for 13% of the global HCV infections. HCV is a substantial precursor for fibrosis, cirrhosis, and hepatocellu...

    Authors: Kholoud Baraka, Rania R. Abozahra, Eman Badr and Sarah M. Abdelhamid
    Citation: BMC Cancer 2023 23:938
    Content type: Research Published on:

  24. Gliomas are the most common malignant brain tumors, with powerful invasiveness and an undesirable prognosis. Actin related protein 2/3 complex subunit 5 (ARPC5) encodes a component of the Arp2/3 protein comple...

    Authors: Yue Ming, Chunyuan Luo, Beihong Ji and Jian Cheng
    Citation: BMC Cancer 2023 23:937
    Content type: Research Published on:

  26. Leucine-rich pentatricopeptide repeat containing (LRPPRC) is a potential oncogene in multiple tumor types, including lung adenocarcinoma, esophageal squamous cell carcinoma and gastric cancer. LRPPRC exerts it...

    Authors: Ziyi Zhao, Yingwei Sun, Jing Tang, Yuting Yang and Xiaochao Xu
    Citation: BMC Cancer 2023 23:935
    Content type: Research Published on:

  27. Recent studies have indicated that epigenetic alterations contribute significantly to lymphoma pathogenesis. A type of epigenetic regulation known as histone acetylation plays a crucial role in transcriptional...

    Authors: Zhuoya Yu, Mengfei Ding, Yiqing Cai, Tiange Lu, Xiaomin Chen, Xiangxiang Zhou and Xin Wang
    Citation: BMC Cancer 2023 23:934
    Content type: Research Published on:

  28. Venous thromboembolism (VTE) is a common postoperative complication in patients undergoing surgery for gastric cancer (GC). Although VTE incidence may vary among cancers, guidelines rarely stratify preventive ...

    Authors: Lin Xiang, Shuai Jin, Yang Yu, Dengfeng Wang and Hao Chen
    Citation: BMC Cancer 2023 23:933
    Content type: Research Published on:

  29. Dietary advanced glycation end products (AGEs) can play an important role in increasing inflammatory factors and oxidative stress as risk factors for cancers. In the present study, we aimed to assess the relat...

    Authors: Mitra Kazemi Jahromi, Asal Neshatbini Tehrani, Hossein Farhadnejad, Hadi Emamat, Hamid Ahmadirad, Farshad Teymoori, Zeinab Heidari, Niloufar Saber, Bahram Rashidkhani and Parvin Mirmiran
    Citation: BMC Cancer 2023 23:932
    Content type: Research Published on:

  30. Detecting a health-promoting lifestyle in colorectal cancer (CRC) survivors is of paramount importance to manage disease complications, prevent their recurrence, and enhance survival; however, no specialized t...

    Authors: Elahe Ramezanzade Tabriz, Monir Ramezani, Abbas Heydari, Seyed Amir Aledavood and Jamshid Jamali
    Citation: BMC Cancer 2023 23:931
    Content type: Research Published on:

  31. Nonsecretory multiple myeloma (NSMM) is a rare type of multiple myeloma (MM). Few studies have described the clinical features and outcomes of NSMM in novel agents. Additionally, the prognostic characteristics...

    Authors: Hailu Sun, Aijun Liu, Lihong Liu, Wei Wang, Zhen Cai, Hua Yan, Lijuan Chen, Guangxun Gao, Fang Wang, Aijun Liao, Bing Chen, Jia Feng, Juan Li, Dong-Ping Huang, Da Gao, Qi-Ke Zhang…
    Citation: BMC Cancer 2023 23:930
    Content type: Research Published on:

  32. Immunoglobulin lambda (Igλ) has been reported to be expressed in many normal and tumor tissues and cells. However, the function and clinical significance of tumor-derived Igλ remain unclear.

    Authors: Juping Wang, Jiangni Huang, Hao Ding, Jing Ma, Haohua Zhong, Fanlu Wang, Yupeng Chen and Hui Peng
    Citation: BMC Cancer 2023 23:929
    Content type: Research Published on:

  33. Gastric cancer (GC) is one of the malignant tumors with the highest mortality worldwide. Our previous studies have revealed that LINC00691 is up-regulated in serum of GC patients as a novel potential biomarker...

    Authors: Bin Xia, Xiuyu Gu, Tingting Xu, Meina Yan, Lan Huang, Chun Jiang, Meifen Li, Guanghua Zhai, Guoping Zhang, Jian Wu, Yu Zhou, Chunrong Sun and Wei Liang
    Citation: BMC Cancer 2023 23:928
    Content type: Research Published on:

  34. The impact of prostate radiotherapy on patient-reported health-related quality of life (HRQoL) significantly influences the outcomes of metastatic prostate cancer. We measured and compared HRQoL of metastatic ...

    Authors: Heba Maged Ayoub, Maha Lotfy Zamzam, Eman Essam Elsemary, Ihab Mohamed Hassanin and Fifi Mostafa Elsayed
    Citation: BMC Cancer 2023 23:927
    Content type: Research Published on:

  35. Tumor cell-monocyte interactions play crucial roles in shaping up the pro-tumorigenic phenotype and functional output of tumor-associated macrophages. Within the tumor microenvironment, such heterotypic cell–c...

    Authors: Asif Amin, Aabid Mustafa Koul, Umer Majeed Wani, Faizah Farooq, Basit Amin, Zubair Wani, Asif Lone, Ayub Qadri and Raies A. Qadri
    Citation: BMC Cancer 2023 23:926
    Content type: Research Published on:

  36. The interferon-induced protein known as guanylate-binding protein 2 (GBP2) has been linked to multiple different cancer types as an oncogenic gene. Although the role of GBP2 in cancer has been preliminarily ex...

    Authors: Yunfei Wang, Jiadong Pan, Fangmei An, Ke Chen, Jiawei Chen, He Nie, Yanping Zhu, Zhengtao Qian and Qiang Zhan
    Citation: BMC Cancer 2023 23:925
    Content type: Research Published on:

  37. Eyelid skin cancers are the most prevalent ophthalmic malignancies. This study aimed to evaluate the association of the Human Development Index (HDI) and lifestyle risk factors with eyelid skin cancers in Iran.

    Authors: Sare Safi, Mohadese Ahmadzade, Saeed Karimi, Mohammad Esmaeil Akbari, Hamidreza Rouientan, Mohammad Abolhosseini, Mozhgan Rezaei Kanavi and Zahra Khorrami
    Citation: BMC Cancer 2023 23:924
    Content type: Research Published on:

  38. Ultra-hypofractionated regimens for definitive prostate cancer (PCa) radiotherapy are increasingly utilized due in part to promising safety and efficacy data complemented by greater patient convenience from a ...

    Authors: Sydney Wolfe, Marshall A. Diven, Ariel E. Marciscano, Xi Kathy Zhou, A. U. Kishan, M. L. Steinberg, Joseph A. Miccio, Philip Camilleri and Himanshu Nagar
    Citation: BMC Cancer 2023 23:923
    Content type: Study Protocol Published on:

  39. Trastuzumab is the only approved target agent for the first-line treatment of human epidermal growth factor receptor-2 (HER-2) positive gastric cancer; however, trastuzumab resistance is a major problem in cli...

    Authors: Yuna Kim, Yoo Jin Bae, Jie-Hyun Kim, Hyunki Kim, Su-Jin Shin, Da Hyun Jung and Hyojin Park
    Citation: BMC Cancer 2023 23:922
    Content type: Research Published on:

  40. Phospholipase C Delta 3 (PLCD3) is a member of phospholipase C(PLC) Protein and PLCD3 protein plays a prominent role in many cancers. However, little is known about the role of PLCD3 in esophageal squamous cel...

    Authors: Mengmeng Wang, Mingjun Gao, Yong Chen, Jun Wu, Xiaolin Wang and Yusheng Shu
    Citation: BMC Cancer 2023 23:921
    Content type: Research Published on:

  41. Despite major advances in cancer therapeutics, the therapeutic options of Lung Squamous Cell Carcinoma (LSCC)-specific remain limited. Furthermore, the current staging system is imperfect for defining a progno...

    Authors: Chen-ye Shao, Jing Luo, Sheng Ju, Chu-ling Li, Cheng Ding, Jun Chen, Xiao-long Liu, Jun Zhao and Li-qin Yang
    Citation: BMC Cancer 2023 23:920
    Content type: Research Published on:

  42. This retrospective analysis of data from clinical trials in metastatic urothelial carcinoma (mUC) was conducted to determine baseline patient characteristics associated with long-term survival (LTS) following ...

    Authors: Marie Alt, Carlos Stecca, Yian Lin, Gbenga Kazeem, Erik T. Goluboff and Srikala S. Sridhar
    Citation: BMC Cancer 2023 23:919
    Content type: Research Published on:

  43. Understanding how patient-reported experiences of care and overall rating of care vary among patients with different characteristics is useful to help interpret results from patient experience surveys and desi...

    Authors: Chantal Arditi, Manuela Eicher, Julien Junod and Isabelle Peytremann-Bridevaux
    Citation: BMC Cancer 2023 23:918
    Content type: Research Published on:

  44. Although research has advanced the field of oncologic geriatrics with survivors to assess their cancer-related needs and devise patient-centered interventions, most of that research has excluded rural populati...

    Authors: Evelyn Arana-Chicas, Laura M. Hincapie Prisco, Saloni Sharma, Fiona Stauffer, Martha McGee, Serge Dauphin, Makiko Ban-Hoefen, Jaime Navarette, Jason Zittel, Ana Paula Cupertino, Allison Magnuson, Karen M. Mustian and Supriya G. Mohile
    Citation: BMC Cancer 2023 23:917
    Content type: Research Published on:

  45. Whether serum lactate dehydrogenase-to-albumin ratio (LAR) influenced the outcomes of colorectal cancer (CRC) patients after radical surgery remained unclear. Therefore, this study sought to examine how LAR in...

    Authors: Xin-Peng Shu, Ying-Chun Xiang, Fei Liu, Yong Cheng, Wei Zhang and Dong Peng
    Citation: BMC Cancer 2023 23:915
    Content type: Research Published on:

  47. The negative effects of the novel coronavirus disease 2019 (COVID-19) pandemic on patients with gastric cancer are poorly understood. This study was designed to compare the short-term and long-term outcomes of...

    Authors: Yong Sun, Chao Chen, Lei Hou and Enhong Zhao
    Citation: BMC Cancer 2023 23:913
    Content type: Research Published on:

  48. Long non-coding RNAs (lncRNAs) play important roles in many pathophysiological processes, including cancer progression. Namely, lncRNA Receptor-tyrosine-kinase-like orphan receptor-1 antisense 1 (ROR1-AS1) is ...

    Authors: Xueliang Li, Zhaowei Sun, Li Wang, Qinlei Wang, Maobing Wang, Jingyun Guo, Haoran Li, MenShou Chen, Guanghua Cao, Yanan Yu, Haochen Zhong, Hao Zou, Kai Ma, Bingyuan Zhang, Guolei Wang and Yujie Feng
    Citation: BMC Cancer 2023 23:912
    Content type: Research Published on:

  50. The goal of therapy for many patients with advanced stage malignancies, including those with metastatic gastric and esophageal cancers, is to extend overall survival while also maintaining quality of life. Aft...

    Authors: Xiaoyuan Ma, Eric Pierce, Harsh Anand, Natalie Aviles, Paul Kunk and Negin Alemazkoor
    Citation: BMC Cancer 2023 23:910
    Content type: Research Published on:

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