Skip to main content

Articles

Page 247 of 332

  1. Cortidis rhizoma (Huanglian) and its major therapeutic component, berberine, have drawn extensive attention in recent years for their anti-cancer properties. Growth inhibitory effects of berberine on multiple ty...

    Authors: Chi Man Tsang, Yuk Chun Cheung, Vivian Wai-Yan Lui, Yim Ling Yip, Guitao Zhang, Victor Weitao Lin, Kenneth Chat-Pan Cheung, Yibin Feng and Sai Wah Tsao
    Citation: BMC Cancer 2013 13:619
  2. Knowledge on immunosuppressive factors in the pathogenesis of endometrial cancer is scarce. The aim of this study was to assess Glycodelin (Gd) and its immunosuppressive isoform Glycodelin A (GdA) in endometri...

    Authors: Miriam Lenhard, Sabine Heublein, Christiane Kunert-Keil, Thomas Vrekoussis, Isabel Lomba, Nina Ditsch, Doris Mayr, Klaus Friese and Udo Jeschke
    Citation: BMC Cancer 2013 13:616
  3. The gold standard of HER2 status assessment in breast cancer is still debated. Immunohistochemistry (IHC) and in-situ technology as fluorescent-labeled methodology (FISH) can be influenced by pre-analytical facto...

    Authors: Zsuzsanna Varga, Aurelia Noske, Constanze Ramach, Barbara Padberg and Holger Moch
    Citation: BMC Cancer 2013 13:615
  4. There is increasing ambiguity towards national mammographic screening programs due to varying publicized estimates of overdiagnosis, i.e., breast cancer that would not have been diagnosed in the women’s lifeti...

    Authors: Eiliv Lund, Nicolle Mode, Marit Waaseth and Jean-Christophe Thalabard
    Citation: BMC Cancer 2013 13:614
  5. Cancer vaccine is one of the attractive treatment modalities for patients with castration-resistant prostate cancer (CRPC). However, because of delayed immune responses, its clinical benefits, besides for over...

    Authors: Masanori Noguchi, Fukuko Moriya, Shigetaka Suekane, Rei Ohnishi, Satoko Matsueda, Tetsuro Sasada, Akira Yamada and Kyogo Itoh
    Citation: BMC Cancer 2013 13:613
  6. Tamoxifen has dramatically reduced the recurrence and mortality rate of estrogen receptor positive breast cancer. However, the efficacy of tamoxifen varies between individuals and 40% of patients will have a r...

    Authors: Nynke GL Jager, Rutger HT Koornstra, Andrew D Vincent, Ron HN van Schaik, Alwin DR Huitema, Tiny M Korse, Jan HM Schellens, Sabine C Linn and Jos H Beijnen
    Citation: BMC Cancer 2013 13:612
  7. Optimization of chemotherapy effectiveness in metastatic colorectal cancers (mCRC) is a major endpoint to enhance the possibility of curative intent surgery. FOLFIRI3 has shown promising results as second-line...

    Authors: Stefano Kim, Erion Dobi, Marine Jary, Franck Monnien, Elsa Curtit, Thierry NGuyen, Zaher Lakkis, Bruno Heyd, Serge Fratte, Denis Cléau, Najib Lamfichekh, Virginie Nerich, Boris Guiu, Martin Demarchi and Christophe Borg
    Citation: BMC Cancer 2013 13:611
  8. Randomized controlled trials have established concurrent chemo-radiotherapy as the preferred treatment option for inoperable local-regionally advanced head and neck squamous cell carcinomas (HNSCCs). Because m...

    Authors: Michael Schlumpf, Claude Fischer, Diana Naehrig, Christoph Rochlitz and Martin Buess
    Citation: BMC Cancer 2013 13:610
  9. Information on the underlying cause of death of cancer patients is of interest because it can be used to estimate net survival. The population-based Geneva Cancer Registry is unique because registrars are able...

    Authors: Robin Schaffar, Elisabetta Rapiti, Bernard Rachet and Laura Woods
    Citation: BMC Cancer 2013 13:609
  10. Aberrant methylation at imprinted differentially methylated regions (DMRs) in human 11p15.5 has been reported in many tumors including hepatoblastoma. However, the methylation status of imprinted DMRs in impri...

    Authors: Janette Mareska Rumbajan, Toshiyuki Maeda, Ryota Souzaki, Kazumasa Mitsui, Ken Higashimoto, Kazuhiko Nakabayashi, Hitomi Yatsuki, Kenichi Nishioka, Ryoko Harada, Shigehisa Aoki, Kenichi Kohashi, Yoshinao Oda, Kenichiro Hata, Tsutomu Saji, Tomoaki Taguchi, Tatsuro Tajiri…
    Citation: BMC Cancer 2013 13:608
  11. A pathway-based genotyping analysis suggested rs2078486 was a novel TP53 SNP, but very few studies replicate this association. TP53 rs1042522 is the most commonly studied SNP, but very few studies examined its po...

    Authors: Yanli Li, Shen-Chih Chang, Rungui Niu, Li Liu, Christina R Crabtree-Ide, Baoxing Zhao, Jianping Shi, Xiaoyou Han, Jiawei Li, Jia Su, Lin Cai, Shunzhang Yu, Zuo-Feng Zhang and Lina Mu
    Citation: BMC Cancer 2013 13:607
  12. Despite an initial good response to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI), resistance to treatment eventually develops. Although several resistance mechanisms have been discov...

    Authors: Wonjun Ji, Chang-Min Choi, Jin Kyung Rho, Se Jin Jang, Young Soo Park, Sung-Min Chun, Woo Sung Kim, Jung-Shin Lee, Sang-We Kim, Dae Ho Lee and Jae Cheol Lee
    Citation: BMC Cancer 2013 13:606
  13. Chk1 inhibitors have emerged as promising anticancer therapeutic agents particularly when combined with antimetabolites such as gemcitabine, cytarabine or hydroxyurea. Here, we address the importance of approp...

    Authors: Ryan Montano, Ruth Thompson, Injae Chung, Huagang Hou, Nadeem Khan and Alan Eastman
    Citation: BMC Cancer 2013 13:604
  14. Nonpolypoid adenomas are a subgroup of colorectal adenomas that have been associated with a more aggressive clinical behaviour compared to their polypoid counterparts. A substantial proportion of nonpolypoid a...

    Authors: Quirinus JM Voorham, Jerry Janssen, Marianne Tijssen, Suzanne Snellenberg, Sandra Mongera, Nicole CT van Grieken, Heike Grabsch, Martin Kliment, Bjorn J Rembacken, Chris JJ Mulder, Manon van Engeland, Gerrit A Meijer, Renske DM Steenbergen and Beatriz Carvalho
    Citation: BMC Cancer 2013 13:603
  15. Recent genomic evidence suggests frequent phosphatidylinositide 3-kinase (PI3K) pathway activation in human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma. Mutations/amplification of the g...

    Authors: Simion I Chiosea, Jennifer R Grandis, Vivian W Y Lui, Brenda Diergaarde, Jessica H Maxwell, Robert L Ferris, Seungwon W Kim, Alyssa Luvison, Megan Miller and Marina N Nikiforova
    Citation: BMC Cancer 2013 13:602
  16. Glutaminase 2 (Gls2) is a p53 target gene and is known to play an important role in energy metabolism. Gls2 has been reported to be downregulated in human hepatocellular carcinomas (HCC). However, the underlyi...

    Authors: Jianbin Zhang, Cheng Wang, Mingquan Chen, Jianping Cao, Ying Zhong, Liting Chen, Han-Ming Shen and Dajing Xia
    Citation: BMC Cancer 2013 13:601
  17. The epidermal growth factor receptor (EGFR)/RAS/RAF/MEK/MAPK pathway is an important pathway in the carcinogenesis, invasion and metastasis of colorectal cancers (CRCs). We conducted a retrospective study to d...

    Authors: Ching-Wen Huang, Hsiang-Lin Tsai, Yi-Ting Chen, Chun-Ming Huang, Cheng-Jen Ma, Chien-Yu Lu, Chao-Hung Kuo, Deng-Chyang Wu, Chee-Yin Chai and Jaw-Yuan Wang
    Citation: BMC Cancer 2013 13:599
  18. Worldwide more than one million women are annually diagnosed with breast cancer. A considerable fraction of these women receive systemic adjuvant therapy; however, some are cured by primary surgery and radioth...

    Authors: Stine B Thorsen, Sarah LT Christensen, Sidse Ø Würtz, Martin Lundberg, Birgitte S Nielsen, Lena Vinther, Mick Knowles, Nick Gee, Simon Fredriksson, Susanne Møller, Nils Brünner, Anne-Sofie Schrohl and Jan Stenvang
    Citation: BMC Cancer 2013 13:598
  19. Epidermal growth factor (EGF) receptors contribute to the development of malignant glioma. Here we considered the possible implication of the EGFR ligand epiregulin (EREG) in glioma development in relation to ...

    Authors: Gregor Auf, Arnaud Jabouille, Maylis Delugin, Sylvaine Guérit, Raphael Pineau, Sophie North, Natalia Platonova, Marlène Maitre, Alexandre Favereaux, Peter Vajkoczy, Masaharu Seno, Andreas Bikfalvi, Dmitri Minchenko, Oleksandr Minchenko and Michel Moenner
    Citation: BMC Cancer 2013 13:597
  20. Androgen deprivation therapy (ADT) is a cornerstone in the treatment of advanced prostate cancer. Adverse musculoskeletal and cardiovascular effects of ADT are widely reported and investigations into the poten...

    Authors: Jacob Uth, Jakob Friis Schmidt, Jesper Frank Christensen, Therese Hornstrup, Lars Juel Andersen, Peter Riis Hansen, Karl Bang Christensen, Lars Louis Andersen, Eva Wulff Helge, Klaus Brasso, Mikael Rørth, Peter Krustrup and Julie Midtgaard
    Citation: BMC Cancer 2013 13:595
  21. Excision repair cross-complementing group 2 (ERCC2) plays important roles in the repair of DNA damage and adducts. Single nucleotide polymorphisms (SNPs) of ERCC2 gene are suspected to influence the risks of ora...

    Authors: Enjiao Zhang, Zhigang Cui, Zhongfei Xu, Weiyi Duan, Shaohui Huang, Xuexin Tan, Zhihua Yin, Changfu Sun and Li Lu
    Citation: BMC Cancer 2013 13:594
  22. The WW domain containing protein WWOX has been postulated to behave as a tumor suppressor in breast and other cancers. Expression of this protein is lost in over 70% of ER negative tumors. This prompted us to ...

    Authors: Brent W Ferguson, Xinsheng Gao, Maciej J Zelazowski, Jaeho Lee, Collene R Jeter, Martin C Abba and C Marcelo Aldaz
    Citation: BMC Cancer 2013 13:593
  23. Our group has previously shown that EPHRIN-A1 and SCINDERIN expression by tumor cells rendered them resistant to cytotoxic T lymphocyte-mediated lysis. Whereas the prognostic value of EPHRIN-A1 expression in c...

    Authors: Meriem Hasmim, Cécile Badoual, Philippe Vielh, Françoise Drusch, Virginie Marty, Agnès Laplanche, Mariana de Oliveira Diniz, Hélène Roussel, Eléonore De Guillebon, Stéphane Oudard, Stéphane Hans, Eric Tartour and Salem Chouaib
    Citation: BMC Cancer 2013 13:592
  24. Neoadjuvant chemoradiotherapy has been newly included in the NCCN guidelines as a treatment option for stage IIB/III soft tissue sarcomas. Whether radiographic response to neoadjuvant therapy correlates with i...

    Authors: Yong Chen, Yun Yang, ChunMeng Wang and YingQiang Shi
    Citation: BMC Cancer 2013 13:591
  25. Src tyrosine kinase activates inducible nitric oxide synthase (iNOS) and, in turn, nitric oxide production as a means to transduce cell migration. Src tyrosine kinase plays a key proximal role to control α9β1 ...

    Authors: Thompson Zhuang, Bharath Chelluboina, Shivani Ponnala, Kiran Kumar Velpula, Azeem A Rehman, Chandramu Chetty, Eleonora Zakharian, Jasti S Rao and Krishna Kumar Veeravalli
    Citation: BMC Cancer 2013 13:590
  26. Dovitinib (TKI-258) is a receptor tyrosine kinase (RTK) inhibitor targeting fibroblast growth factor receptor (FGFR) and further related RTKs. TKI-258 is under investigation as anticancer drug for the treatmen...

    Authors: Jörg Hänze, Marcus Henrici, Axel Hegele, Rainer Hofmann and Peter J Olbert
    Citation: BMC Cancer 2013 13:589
  27. To assess the trends of risk classification and primary therapy in Japanese patients who were diagnosed with prostate cancer between 2004-2006 and 2007-2009.

    Authors: Nobumichi Tanaka, Akihide Hirayama, Tatsuo Yoneda, Katsunori Yoshida, Keiji Shimada, Noboru Konishi and Kiyohide Fujimoto
    Citation: BMC Cancer 2013 13:588
  28. The genetic changes in gastric adenocarcinoma are extremely complex and reliable tumor markers have not yet been identified. There are also remarkable geographical differences in the distribution of this disea...

    Authors: Lars L Eftang, Ying Esbensen, Tone M Tannæs, Gustav P Blom, Ida RK Bukholm and Geir Bukholm
    Citation: BMC Cancer 2013 13:586
  29. Desmoplastic small round cell tumor (DSRCT) is characterized by the presence of a fusion protein EWS/WT1, arising from the t (11;22) (p13;q12) translocation. Here we examine the oncogenic properties of two spl...

    Authors: Pratiti Bandopadhayay, Anissa M Jabbour, Christopher Riffkin, Marika Salmanidis, Lavinia Gordon, Dean Popovski, Lin Rigby, David M Ashley, David N Watkins, David M Thomas, Elizabeth Algar and Paul G Ekert
    Citation: BMC Cancer 2013 13:585
  30. The association of reproductive factors with hormone receptor (HR)-negative breast tumors remains uncertain.

    Authors: Rebecca Ritte, Kaja Tikk, Annekatrin Lukanova, Anne Tjønneland, Anja Olsen, Kim Overvad, Laure Dossus, Agnès Fournier, Françoise Clavel-Chapelon, Verena Grote, Heiner Boeing, Krasimira Aleksandrova, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Domenico Palli…
    Citation: BMC Cancer 2013 13:584
  31. This study evaluated the efficacy and safety of S-1 combined with docetaxel (SD) following doxorubicin plus cyclophosphamide (AC) as neoadjuvant therapy in patients with HER2-negative, stage II-III breast cancer.

    Authors: Yong Wha Moon, Soohyeon Lee, Byeong-Woo Park, Eun-Kyung Kim, Seung Il Kim, Ja Seung Koo, Seho Park, Min Jung Kim, Hyun Cheol Chung, Joo-Hang Kim and Joohyuk Sohn
    Citation: BMC Cancer 2013 13:583
  32. We previously found that the low frequency magnetic fields (LF-MF) inhibited gastric and lung cancer cell growth. We suppose that exposure to LF-MF may modulate immune function so as to inhibit tumor. We here ...

    Authors: Yunzhong Nie, Leilei Du, Yongbin Mou, Zhenjun Xu, Leihua Weng, Youwei Du, Yanan Zhu, Yayi Hou and Tingting Wang
    Citation: BMC Cancer 2013 13:582
  33. Serine-threonine inhibitors, such as vemurafenib, are being used increasingly in cancer treatment, and the toxicity and therapeutic benefit need to be balanced carefully both before and during treatment.

    Authors: Mahesh Iddawela, Sarah Crook, Leah George, Amit Lakkaraju, Nihal Nanayakkara, Roland Hunt and William R Adam
    Citation: BMC Cancer 2013 13:581
  34. Osteosarcoma is the most frequent primary malignant bone tumor, notorious for its lung metastasis. Shikonin, an effective constituent extracted from Chinese medicinal herb, was demonstrated to induce necroptos...

    Authors: Zeze Fu, Biyong Deng, Yuxin Liao, Liancheng Shan, Fei Yin, Zhuoying Wang, Hui Zeng, Dongqing Zuo, Yingqi Hua and Zhengdong Cai
    Citation: BMC Cancer 2013 13:580
  35. Owing to the high mortality and rapidly growing costs related to lung cancer, it is worth examining the health benefits of prevention for major types of lung cancer. This study attempts to quantify the quality...

    Authors: Szu-Chun Yang, Wu-Wei Lai, Wu-Chou Su, Shang-Yin Wu, Helen HW Chen, Yi-Lin Wu, Mei-Chuan Hung and Jung-Der Wang
    Citation: BMC Cancer 2013 13:579
  36. Esophageal cancer is the sixth leading cause of cancer death worldwide; current early detection screening tests are inadequate. Esophageal balloon cytology successfully retrieves exfoliated and scraped superfi...

    Authors: Shih-Wen Lin, Christian C Abnet, Neal D Freedman, Gwen Murphy, Rosana Risques, Donna Prunkard, Peter Rabinovitch, Qin-Jing Pan, Mark J Roth, Guo-Qing Wang, Wen-Qiang Wei, Ning Lu, Philip R Taylor, You-Lin Qiao and Sanford M Dawsey
    Citation: BMC Cancer 2013 13:578
  37. Palliative gastrectomy for patients with advanced gastric cancer remains controversial. The objective of the present meta-analysis was to analyze survival outcomes and establish a consensus on whether palliati...

    Authors: Jingxu Sun, Yongxi Song, Zhenning Wang, Xiaowan Chen, Peng Gao, Yingying Xu, Baosen Zhou and Huimian Xu
    Citation: BMC Cancer 2013 13:577
  38. Circumferential resection margin (CRM) and distal resection margin (DRM) have different impact on clinical outcomes after preoperative chemoradiotherapy (CRT) followed by surgery. Effect and adequate length of...

    Authors: Joo Ho Lee, Eui Kyu Chie, Kyubo Kim, Seung-Yong Jeong, Kyu Joo Park, Jae-Gahb Park, Gyeong Hoon Kang, Sae-Won Han, Do-Youn Oh, Seock-Ah Im, Tae-You Kim, Yung-Jue Bang and Sung W Ha
    Citation: BMC Cancer 2013 13:576
  39. Flotillin-1 and flotillin-2 are two homologous and ubiquitously expressed proteins that are involved in signal transduction and membrane trafficking. Recent studies have reported that flotillins promote breast...

    Authors: Nina Kurrle, Wymke Ockenga, Melanie Meister, Frauke Völlner, Sina Kühne, Bincy A John, Antje Banning and Ritva Tikkanen
    Citation: BMC Cancer 2013 13:575
  40. Tumor cells benefit from their ability to avoid apoptosis and invade other tissues. The endoplasmic reticulum (ER) membrane protein Sec62 is a key player in these processes. Sec62 is essential for cell migrati...

    Authors: Maximilian Linxweiler, Stefan Schorr, Nico Schäuble, Martin Jung, Johannes Linxweiler, Frank Langer, Hans-Joachim Schäfers, Adolfo Cavalié, Richard Zimmermann and Markus Greiner
    Citation: BMC Cancer 2013 13:574
  41. We are using ACI and BN rats, which differ markedly in their susceptibility to 17β-estradiol (E2)-induced mammary cancer, to identify genetic variants and environmental factors that determine mammary cancer su...

    Authors: Lina Ding, Yang Zhao, Christopher L Warren, Ruth Sullivan, Kevin W Eliceiri and James D Shull
    Citation: BMC Cancer 2013 13:573
  42. While recent research has shown that expression of ZEB-1 in a variety of tumors has a crucial impact on patient survival, there is little information regarding ZEB-1 expression in hepatocellular carcinoma (HCC...

    Authors: Motoyuki Hashiguchi, Shinichi Ueno, Masahiko Sakoda, Satoshi Iino, Kiyokazu Hiwatashi, Koji Minami, Kei Ando, Yuko Mataki, Kosei Maemura, Hiroyuki Shinchi, Sumiya Ishigami and Shoji Natsugoe
    Citation: BMC Cancer 2013 13:572
  43. Phenethyl isothiocyanate (PEITC) is a cancer chemopreventive agent from cruciferous vegetables. Cholangiocarcinoma (CCA) is a chemo-resistant cancer with very poor prognosis. We evaluated the effects of PEITC ...

    Authors: Ornanong Tusskorn, Laddawan Senggunprai, Auemduan Prawan, Upa Kukongviriyapan and Veerapol Kukongviriyapan
    Citation: BMC Cancer 2013 13:571
  44. The placenta-specific 1 (PLAC1) gene encodes a membrane-associated protein which is selectively expressed in the placental syncytiotrophoblast and in murine fetal tissues during embryonic development. In contrast...

    Authors: Meike Wagner, Michael Koslowski, Claudia Paret, Marcus Schmidt, Özlem Türeci and Ugur Sahin
    Citation: BMC Cancer 2013 13:570
  45. Biomarkers allowing the characterization of malignancy and therapy response of oral squamous cell carcinomas (OSCC) or other types of carcinomas are still outstanding. The biochemical suicide molecule endonucl...

    Authors: Martin Grimm, Steffen Schmitt, Peter Teriete, Thorsten Biegner, Arnulf Stenzl, Jörg Hennenlotter, Hans-Joachim Muhs, Adelheid Munz, Tatjana Nadtotschi, Klemens König, Jörg Sänger, Oliver Feyen, Heiko Hofmann, Siegmar Reinert and Johannes F Coy
    Citation: BMC Cancer 2013 13:569
  46. Optimal therapy for patients with unresectable locally advanced extrahepatic cholangiocarcinoma (ULAC) remains controversial. We analysed the role of radiotherapy in the management of such tumors.

    Authors: Laurence Moureau-Zabotto, Olivier Turrini, Michel Resbeut, Jean-Luc Raoul, Marc Giovannini, Flora Poizat, Gilles Piana, Jean-Robert Delpero and Francois Bertucci
    Citation: BMC Cancer 2013 13:568

Featured videos

View featured videos from across the BMC-series journals