Goncharenko-Khaider N, Lane D, Matte I, Rancourt C, Piché A: Targeted ovarian cancer treatment: the TRAILs of resistance. Am J Cancer Res. 2012, 2: 75-92.
Google Scholar
Ashkenazi A, Dixit VM: Death receptors: signaling and modulation. Science. 1998, 281: 1305-1308.
Article
CAS
PubMed
Google Scholar
Ashkenazi A, Holland P, Eckhardt SG: Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). J Clin Oncol. 2008, 26: 3621-3630. 10.1200/JCO.2007.15.7198.
Article
CAS
PubMed
Google Scholar
Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, Chin W, Jones J, Woodward A, Le T, Smith C, Smolak P, Goodwin RG, Rauch CT, Schuh JC, Lynch DH: Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med. 1999, 5: 157-163. 10.1038/5517.
Article
CAS
PubMed
Google Scholar
Ozören N, El-Deiry WS: Cell surface death receptor signaling in normal and cancer cells. Semin Cancer Biol. 2003, 13: 135-147. 10.1016/S1044-579X(02)00131-1.
Article
PubMed
Google Scholar
Wajant H, Pfizenmaier K, Scheurich P: TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy. Apoptosis. 2002, 7: 449-459. 10.1023/A:1020039225764.
Article
CAS
PubMed
Google Scholar
Lane D, Cartier A, L’Espérance S, Côté M, Rancourt C, Piché A: Differential induction of apoptosis by tumor necrosis factor-related apoptosis-inducing ligand in human ovarian carcinoma cells. Gynecol Oncol. 2004, 93: 594-604. 10.1016/j.ygyno.2004.03.029.
Article
CAS
PubMed
Google Scholar
Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A: Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity. 2000, 12: 611-620. 10.1016/S1074-7613(00)80212-5.
Article
CAS
PubMed
Google Scholar
Degli-Esposti MA, Smolak PJ, Walczak H, Waugh J, Huang CP, DuBose RF, Goodwin RG, Smith CA: Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J Exp Med. 1997, 186: 1165-1170. 10.1084/jem.186.7.1165.
Article
CAS
PubMed
PubMed Central
Google Scholar
Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG: The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity. 1997, 7: 813-820. 10.1016/S1074-7613(00)80399-4.
Article
CAS
PubMed
Google Scholar
Emery JG, McDonnell P, Burke MB, Deen KC, Lyn S, Silverman C, Dul E, Appelbaum ER, Eichman C, DiPrinzio R, Dodds RA, James IE, Rosenberg M, Lee JC, Young PR: Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem. 1998, 273: 14363-14367. 10.1074/jbc.273.23.14363.
Article
CAS
PubMed
Google Scholar
Kischkel FC, Hellbardt S, Berhmann I, Germer M, Pawlita M, Krammer PH, Peter ME: Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 1995, 14: 5579-5588.
CAS
PubMed
PubMed Central
Google Scholar
Krueger A, Baumann S, Krammer PH, Kirchhoff S: FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis. Mol Cell Biol. 2001, 21: 8247-8254. 10.1128/MCB.21.24.8247-8254.2001.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bagnoli M, Canevari S, Mezzanzanica D: Cellular FLICE-inhibitory protein (c-FLIP) signalling: a key regulator of receptor-mediated apoptosis in physiologic context and in cancer. Int J Biochem Cell Biol. 2010, 42: 210-213. 10.1016/j.biocel.2009.11.015.
Article
CAS
PubMed
Google Scholar
O’Brien TJ, Beard JB, Underwood LJ, Dennis RA, Santin AD, York L: The CA 125 gene: an extracellular superstructure dominated by repeat sequences. Tumour Biol. 2001, 22: 348-366. 10.1159/000050638.
Article
PubMed
Google Scholar
O’Brien TJ, Beard JB, Underwood LJ, Shigemasa K: The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure. Tumour Biol. 2002, 23: 154-169. 10.1159/000064032.
Article
PubMed
Google Scholar
Yin BW, Lloyd KO: Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16. J Biol Chem. 2001, 276: 27371-27375. 10.1074/jbc.M103554200.
Article
CAS
PubMed
Google Scholar
Yin BW, Dnistrian A, Lloyd KO: Ovarian cancer antigen CA125 is encoded by the MUC16 mucin gene. Int J Cancer. 2002, 98: 737-740. 10.1002/ijc.10250.
Article
CAS
PubMed
Google Scholar
Kabawat SE, Bast RC, Welch WR, Knapp RC, Colvin RB: Immunopathologic characterization of a monoclonal antibody that recognizes common surface antigens of human ovarian tumors of serous, endometrioid, and clear cell types. Am J Clin Pathol. 1983, 79: 98-104.
Article
CAS
PubMed
Google Scholar
Gubbels JA, Belisle J, Onda M, Rancourt C, Migneault M, Ho M, Bera TK, Connor J, Sathyanarayana BK, Lee B, Pastan I, Patankar MS: Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors. Mol Cancer. 2006, 5: 50-10.1186/1476-4598-5-50.
Article
PubMed
PubMed Central
Google Scholar
Kaneko O, Gong L, Zhang J, Hansen JK, Hassan R, Lee B, Ho M: A binding domain on mesothelin for CA125/MUC16. J Biol Chem. 2009, 284: 3739-3749. 10.1074/jbc.M806776200.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rump A, Morikawa Y, Tanaka M, Minami S, Umesaki N, Takeuchi M, Miyajima A: Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion. J Biol Chem. 2004, 279: 9190-9198. 10.1074/jbc.M312372200.
Article
CAS
PubMed
Google Scholar
Argüeso P, Guzman-Aranguez A, Mantelli F, Cao Z, Ricciuto J, Panjwani N: Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier. J Biol Chem. 2009, 284: 23037-23045. 10.1074/jbc.M109.033332.
Article
PubMed
PubMed Central
Google Scholar
Belisle JA, Horibata S, Jennifer GA, Petrie S, Kapur A, André S, Gabius HJ, Rancourt C, Connor J, Paulson JC, Patankar MS: Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes. Mol Cancer. 2010, 9: 118-10.1186/1476-4598-9-118.
Article
PubMed
PubMed Central
Google Scholar
Gubbels JA, Felder M, Horibata S, Belisle JA, Kapur A, Holden H, Petrie S, Migneault M, Rancourt C, Connor JP, Patankar MS: MUC16 provides immune protection by inhibiting synapse formation between NK cells and ovarian tumor cells. Mol Cancer. 2010, 9: 11-10.1186/1476-4598-9-11.
Article
PubMed
PubMed Central
Google Scholar
Thériault C, Pinard M, Comamala M, Migneault M, Beaudin J, Matte I, Boivin M, Piché A, Rancourt C: MUC16 (CA125) regulates epithelial ovarian cancer cell growth, tumorigenesis and metastasis. Gynecol Oncol. 2011, 121: 434-443. 10.1016/j.ygyno.2011.02.020.
Article
PubMed
Google Scholar
Boivin M, Lane D, Piché A, Rancourt C: CA125 (MUC16) tumor antigen selectively modulates the sensitivity of ovarian cancer cells to genotoxic drug-induced apoptosis. Gynecol Oncol. 2009, 115: 407-413. 10.1016/j.ygyno.2009.08.007.
Article
CAS
PubMed
Google Scholar
Lane D, Côté M, Grondin M, Couture MC, Piché A: Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3. Mol Cancer Ther. 2006, 5: 509-521. 10.1158/1535-7163.MCT-05-0362.
Article
CAS
PubMed
Google Scholar
Ott M, Norberg E, Zhivotovsky B, Orrenius S: Mitochondrial targeting of tBid/Bax: a role for the TOM complex?. Cell Death Differ. 2009, 16: 1075-1082. 10.1038/cdd.2009.61.
Article
CAS
PubMed
Google Scholar
Kim K, Fisher MJ, Xu SQ, El-Deiry WS: Molecular determinants of response to TRAIL in killing of normal and cancer cells. Clin Cancer Res. 2000, 6: 335-346.
CAS
PubMed
Google Scholar
Bast RC, Klug TL, St John E, Jenison E, Niloff JM, Lazarus H, Berkowitz RS, Leavitt T, Griffiths CT, Parker L, Zurawski VR, Knapp RC: A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer. N Engl J Med. 1983, 309: 883-887. 10.1056/NEJM198310133091503.
Article
PubMed
Google Scholar
Hogdall EV, Christensen L, Kjaer SK, Blaakaer J, Kjaerbye-Thygesen A, Gayther S, Jacobs IJ, Hogdall CK: CA125 expression pattern, prognosis and correlation with serum CA125 in ovarian tumor patients. From the Danish “MALOVA” ovarian cancer study. Gynecol Oncol. 2007, 104: 508-515. 10.1016/j.ygyno.2006.09.028.
Article
CAS
PubMed
Google Scholar
Hilkens J, Ligtenberg MJ, Vos HL, Litvinov SV: Cell membrane-associated mucins and their adhesion-modulating property. Trends Biochem Sci. 1992, 17: 359-363. 10.1016/0968-0004(92)90315-Z.
Article
CAS
PubMed
Google Scholar
Wesseling J, van der Valk SW, Vos HL, Sonnenberg A, Hilkens J: Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components. J Cell Biol. 1995, 129: 255-265. 10.1083/jcb.129.1.255.
Article
CAS
PubMed
Google Scholar
Komatsu M, Jepson S, Arango ME, Carothers Carraway CA, Carraway KL: Muc4/sialomucin complex, an intramembrane modulator of ErbB2/HER2/Neu, potentiates primary tumor growth and suppresses apoptosis in a xenotransplanted tumor. Oncogene. 2001, 20: 461-470. 10.1038/sj.onc.1204106.
Article
CAS
PubMed
Google Scholar
Satoh S, Hinoda Y, Hayashi T, Burdick MD, Imai K, Hollingsworth MA: Enhancement of metastatic properties of pancreatic cancer cells by MUC1 gene encoding an anti-adhesion molecule. Int J Cancer. 2000, 88: 507-518. 10.1002/1097-0215(20001115)88:4<507::AID-IJC1>3.0.CO;2-0.
Article
CAS
PubMed
Google Scholar
Singh AP, Moniaux N, Chauhan SC, Meza JL, Batra SK: Inhibition of MUC4 expression suppresses pancreatic tumor cell growth and metastasis. Cancer Res. 2004, 64: 622-630. 10.1158/0008-5472.CAN-03-2636.
Article
CAS
PubMed
Google Scholar
McDermott KM, Crocker PR, Harris A, Burdick MD, Hinoda Y, Hayashi T, Imai K, Hollingsworth MA: Overexpression of MUC1 reconfigures the binding properties of tumor cells. Int J Cancer. 2001, 94: 783-791. 10.1002/ijc.1554.
Article
CAS
PubMed
Google Scholar
Agata N, Ahmad R, Kawano T, Raina D, Kharbanda S, Kufe D: MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8. Cancer Res. 2008, 68: 6136-6144. 10.1158/0008-5472.CAN-08-0464.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ren J, Agata N, Chen D, Li Y, Yu WH, Huang L, Raina D, Chen W, Kharbanda S, Kufe D: Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell. 2004, 5: 163-175. 10.1016/S1535-6108(04)00020-0.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rancourt C, Matte I, Lane D, Piché A: The role of MUC16 mucin (CA125) in the pathogenesis of ovarian cancer. Ovarian cancer: basic science perspective. Volume 1. Edited by: Farghaly SA. 2012, Croatia: InTech, 67-84. 1
Google Scholar
Goncharenko-Khaider N, Lane D, Matte I, Rancourt C, Piché A: Biological significance of apoptosis in ovarian cancer: TRAIL therapeutic targeting. Ovarian cancer: a clinical and translational update. Volume 1. Edited by: Diaz-Padilla I. 2013, Croatia: InTech, 227-250. 1
Google Scholar
Lakshmanan I, Ponnusamy MP, Das S, Chakraborty S, Haridas D, Mukhopadhyay P, Lele SM, Batra SK: MUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells. Oncogene. 2012, 31: 805-817. 10.1038/onc.2011.297.
Article
CAS
PubMed
Google Scholar
Dodier P, Piché A: Bcl-X(L) is functionally non-equivalent for the regulation of growth and survival in human ovarian cancer cells. Gynecol Oncol. 2006, 100: 254-263. 10.1016/j.ygyno.2005.08.028.
Article
CAS
PubMed
Google Scholar