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  1. Patients with immunocompromise were suspected to encounter a high risk for severe coronavirus disease 2019 (COVID-19) infection on early period; however, data is lacking nowadays and immune response remain unc...

    Authors: Na Zhang, Zhen Wang, Hong Li, Kai Chen, Hong-sheng Wang, Jing-bo Shao, Sha-yi Jiang, Xiao-wen Zhai and Hui Jiang
    Citation: BMC Cancer 2024 24:538
    Content type: Research Published on:

  2. The tripartite motif (TRIM) proteins have been reported to play crucial roles in various malignancies. However, the clinical significance of TRIM proteins in colorectal cancer (CRC) remains controversial. This...

    Authors: Ying Wu, Chen Chen, Xian Hua, Chunhua Zhao and Han Min
    Citation: BMC Cancer 2024 24:537
    Content type: Research Published on:

  3. Cervical lymph node metastasis (LNM) is an important prognostic factor for patients with non-small cell lung cancer (NSCLC). We aimed to develop and validate machine learning models that use ultrasound radiomi...

    Authors: Zhiqiang Deng, Xiaoling Liu, Renmei Wu, Haoji Yan, Lingyun Gou, Wenlong Hu, Jiaxin Wan, Chenwanqiu Song, Jing Chen, Daiyuan Ma, Haining Zhou and Dong Tian
    Citation: BMC Cancer 2024 24:536
    Content type: Research Published on:

  4. Immunotherapy based on the application of immune checkpoint inhibitors (ICIs) is one of the standard treatments for advanced non-small cell lung cancer (NSCLC). Non-alcoholic fatty liver Disease (NAFLD) has de...

    Authors: Yi Li, Bingxin Gong, Yusheng Guo, Weiwei Liu, Chao Chen, Shanshan Jiang, Feng Pan, Jiyu Song, Lian Yang and Guofeng Zhou
    Citation: BMC Cancer 2024 24:535
    Content type: Research Published on:

  5. While there is an understanding of the association between the expression of Porphyromonas gingivalis (P. gingivalis) and prognosis of oral squamous cell carcinoma (OSCC), significance specially to address the re...

    Authors: Chenxi Li, Muqiu Li, Wei Wei, Zhengye Wang, Jingwen Yu and Zhongcheng Gong
    Citation: BMC Cancer 2024 24:534
    Content type: Research Published on:

  6. In Saudi Arabia, approximately one-third of colorectal cancer (CRC) patients are diagnosed at an advanced stage. Late diagnosis is often associated with a worse prognosis. Understanding the risk factors for la...

    Authors: Norah Alsadhan, Sultana A Alhurishi, Mar Pujades-Rodriguez, Farag Shuweihdi, Cathy Brennan and Robert M West
    Citation: BMC Cancer 2024 24:533
    Content type: Research Published on:

  7. Aberrant expressions of desmoglein 2 (Dsg2) and desmocollin 2(Dsc2), the two most widely distributed desmosomal cadherins, have been found to play various roles in cancer in a context-dependent manner. Their s...

    Authors: Ji-Yuan Han, Na Che, Jing Mo, Dan-Fang Zhang, Xiao-Hui Liang, Xue-Yi Dong, Xiu-Lan Zhao and Bao-Cun Sun
    Citation: BMC Cancer 2024 24:532
    Content type: Research Published on:

  8. In the pathogenesis of myeloproliferative neoplasms (MPN), inflammation plays an important role. However, it is unclear whether there is a causal link between inflammation and MPNs. We used a bidirectional, tw...

    Authors: Hao Xiong, Huitao Zhang, Jun Bai, Yanhong Li, Lijuan Li and Liansheng Zhang
    Citation: BMC Cancer 2024 24:531
    Content type: Research Published on:

  9. In low-income countries there is insufficient evidence on hematological, clinical, cytogenetic and molecular profiles among new CML patients. Therefore, we performed this study among newly confirmed CML patien...

    Authors: Fekadu Urgessa, Boki Lengiso, Aster Tsegaye, Amha Gebremedhin, Fozia Abdella, Fisihatsion Tadesse, Jerald Radich, Helen Nigussie and Teklu Kuru Gerbaba
    Citation: BMC Cancer 2024 24:530
    Content type: Research Published on:

  12. Tumor Treating Fields (TTFields) Therapy is an FDA-approved therapy in the first line and recurrent setting for glioblastoma. Despite Phase 3 evidence showing improved survival with TTFields, it is not uniform...

    Authors: Priya Kumthekar, Madison Lyleroehr, Leilani Lacson, Rimas V. Lukas, Karan Dixit, Roger Stupp, Timothy Kruser, Jeff Raizer, Alexander Hou, Sean Sachdev, Margaret Schwartz, Jessica Bajas PA, Ray Lezon, Karyn Schmidt, Christina Amidei and Karen Kaiser
    Citation: BMC Cancer 2024 24:527
    Content type: Research Published on:

  13. Panel gene sequencing is an established diagnostic tool for precision oncology of solid tumors, but its utility for the treatment of cancers of the digestive system in clinical routine is less well documented.

    Authors: Lena Dreikhausen, Anna Klupsch, Isabella Wiest, Qiyun Xiao, Nadine Schulte, Johannes Betge, Tobias Boch, Christoph Brochhausen, Timo Gaiser, Ralf-Dieter Hofheinz, Matthias Ebert and Tianzuo Zhan
    Citation: BMC Cancer 2024 24:526
    Content type: Research Published on:

  15. Nutritional impact symptoms (NISs) are proposed to be a key indicator of decreased dietary intake in patients with solid cancer. Cancer patients frequently experience NIS from the disease itself and from disea...

    Authors: Muna H. Shakhshir, Husam T. Salameh, Riad Amer and Sa’ed H. Zyoud
    Citation: BMC Cancer 2024 24:524
    Content type: Research Published on:

  16. Although numerous studies have reported the prognostic value of the lung immune prognostic index (LIPI) in non-small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICIs), the prog...

    Authors: Yusheng Guo, Yao Pan, Jiayu Wan, Bingxin Gong, Yi Li, Xuefeng Kan and Chuansheng Zheng
    Citation: BMC Cancer 2024 24:523
    Content type: Systematic Review Published on:

  17. Metastatic disease is a major and difficult-to-treat complication of lung cancer. Considering insufficient effectiveness of existing therapies and taking into account the current problem of lung cancer chemore...

    Authors: E. Skurikhin, N. Ermakova, M. Zhukova, E. Pan, D. Widera, L. Sandrikina, L. Kogai, O. Pershina, A. Pakhomova, V. Yu. Pan, N. Kushlinskii, A. Kubatiev, S. Morozov and A. Dygai
    Citation: BMC Cancer 2024 24:522
    Content type: Research Published on:

  18. Emerging evidence suggests that the gut microbiota is associated with various intracranial neoplastic diseases. It has been observed that alterations in the gut microbiota are present in gliomas, meningiomas, ...

    Authors: Chunhui Liu, Fangzheng Liu, Ding Nie, Youchao Xiao, Wentao Wu, Yanfei Jia, Lu Jin, Ning Qiao, Kefan Cai, Siming Ru, Xin Liu, Yifan Song, Jintian Xu, Lei Cao and Songbai Gui
    Citation: BMC Cancer 2024 24:521
    Content type: Research Published on:

  19. Acute myeloid leukaemia (AML) is a fatal haematopoietic malignancy and is treated with the conventional combination of cytarabine (Ara-C) and daunorubicin (Dau). The survival rate of AML patients is lower due ...

    Authors: Yang Qiu, Lu Bai, Haosen Zhao and Xifan Mei
    Citation: BMC Cancer 2024 24:520
    Content type: Research Published on:

  20. Uveal melanoma (UVM) is the most common primary intraocular tumor in adults, with a median survival of 4–5 months following metastasis. DNA damage response (DDR) upregulation in UVM, which could be linked to i...

    Authors: Yingxu Zhang, Jinbiao Zheng, Minyu Chen, Shulun Zhao, Ruiqian Ma, Wenwei Chen and Jiahui Liu
    Citation: BMC Cancer 2024 24:519
    Content type: Research Published on:

  21. Children and adolescents diagnosed with cancer often experience psychological distress, encompassing anxiety, depression, and post-traumatic stress disorder (PTSD). This study aimed to evaluate the prevalence ...

    Authors: Laila S. Al-Saadi, Moon Fai Chan, Amal Al Sabahi, Jalila Alkendi, Nawal Al-Mashaikhi, Hana Al Sumri, Amal Al-Fahdi and Mohammed Al-Azri
    Citation: BMC Cancer 2024 24:518
    Content type: Research Published on:

  22. To effectively embed exercise rehabilitation in cancer survivorship care, a co-ordinated system of acute and community exercise rehabilitation services, forming a stepped model of care, is recommended. Patient...

    Authors: Louise Brennan, Grainne Sheill, Sonya Collier, Peter Browne, Claire L. Donohoe, Linda O’Neill, Juliette Hussey and Emer M. Guinan
    Citation: BMC Cancer 2024 24:517
    Content type: Research Published on:

  23. Numerous studies have indicated that cancer-associated fibroblasts (CAFs) play a crucial role in the progression of colorectal cancer (CRC). However, there are still many unknowns regarding the exact role of C...

    Authors: Shangshang Hu, Qianni Xiao, Rui Gao, Jian Qin, Junjie Nie, Yuhan Chen, Jinwei Lou, Muzi Ding, Yuqin Pan and Shukui Wang
    Citation: BMC Cancer 2024 24:516
    Content type: Research Published on:

  25. Medical consortiums have been extensively established to facilitate the integration of health resources and bridge the technical gap among member institutions. However, some commonly appropriate technologies r...

    Authors: Shiyin Wu, Yuhang Zheng, Lingjie Wang and Wenbin Liu
    Citation: BMC Cancer 2024 24:514
    Content type: Research Published on:

  26. [18F]FDG-PET/CT is used for staging and treatment planning in patients with locally advanced cervical cancer (LACC). We studied if a PET-based prediction model could provide additional risk stratification beyond ...

    Authors: J.A. Adam, E. Poel, B.L.F. van Eck Smit, C.H. Mom, L.J.A. Stalpers, J.J. Laan, E. Kidd, J. Stoker and S. Bipat
    Citation: BMC Cancer 2024 24:513
    Content type: Research Published on:

  28. Although papillary thyroid carcinoma (PTC) has a favorable prognosis, it could affect patient life quality and become a serious threat because of invasion and metastasis. Many investigations have suggested tha...

    Authors: Jiying Shen, Zhirong Ma, Jin Yang, Tianzhen Qu, Yu Xia, Yingjie Xu, Ming Zhou and Weiwei Liu
    Citation: BMC Cancer 2024 24:511
    Content type: Research Published on:

  29. To develop a deep learning(DL) model utilizing ultrasound images, and evaluate its efficacy in distinguishing between benign and malignant parotid tumors (PTs), as well as its practicality in assisting clinici...

    Authors: Tian Jiang, Chen Chen, Yahan Zhou, Shenzhou Cai, Yuqi Yan, Lin Sui, Min Lai, Mei Song, Xi Zhu, Qianmeng Pan, Hui Wang, Xiayi Chen, Kai Wang, Jing Xiong, Liyu Chen and Dong Xu
    Citation: BMC Cancer 2024 24:510
    Content type: Research Published on:

  30. Glioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features including extensive hypoxia. Hypoxia in glioblatoma associates with comple...

    Authors: Katerina Dvorakova, Veronika Skarkova, Barbora Vitovcova, Jiri Soukup, Hana Vosmikova, Zuzana Pleskacova, Adam Skarka, Michael Christian Bartos, Petr Krupa, Petra Kasparova, Jiri Petera and Emil Rudolf
    Citation: BMC Cancer 2024 24:509
    Content type: Research Published on:

  31. Circulating tumor cell (CTC) clusters play a critical role in carcinoma metastasis. However, the rarity of CTC clusters and the limitations of capture techniques have retarded the research progress. In vitro C...

    Authors: Jueyao Zou, Qiong Chen, Yong He, Yanhong Pan, Han Zhao, Junfeng Shi, Zhonghong Wei, Suyun Yu, Yang Zhao, Xin Han, Yin Lu and Wenxing Chen
    Citation: BMC Cancer 2024 24:507
    Content type: Research Published on:

  32. N1-methyladenosine (m1A), among the most common internal modifications on RNAs, has a crucial role to play in cancer development. The purpose of this study were systematically investigate the modification charact...

    Authors: Yingmin Wu, Lian Li, Long Wang, Shenjie Zhang, Zhirui zeng, Jieyu Lu, Zhi Wang, Yewei Zhang, Shilong Zhang, Haiyang Li and Tengxiang Chen
    Citation: BMC Cancer 2024 24:506
    Content type: Research Published on:

  33. Lung adenocarcinoma is the main type of lung cancer in women. Our previous findings have evidenced that 25-hydroxycholesterol (25-HC) promotes migration and invasion of lung adenocarcinoma cells (LAC), during ...

    Authors: Mengting He, Wenbo Jiang, Xingkai Li, Hongjin Liu, Hongsheng Ren and Yanliang Lin
    Citation: BMC Cancer 2024 24:505
    Content type: Research Published on:

  34. Leptomeningeal metastasis (LM) of small cell lung cancer (SCLC) is a highly detrimental occurrence associated with severe neurological disorders, lacking effective treatment currently. Proteolysis-targeting ch...

    Authors: Min-xing Shi, Xi Ding, Liang Tang, Wei-jun Cao, Bo Su and Jie Zhang
    Citation: BMC Cancer 2024 24:504
    Content type: Research Published on:

  35. The incidence of early-onset colorectal cancer (EOCRC, diagnosed in patients under the age of 50 years) has been increasing around the world. Here, we aimed to systematically identify distinctive features of E...

    Authors: Hongwei Liu, Huifang Xu, Yin Liu, Yuqian Zhao, Xi Zhang, Yanqin Yu, Lingbin Du, Yunyong Liu, Wenjun Wang, Helu Cao, Li Ma, Juanxiu Huang, Ji Cao, Li Li, Yanping Fan, Xiaofen Gu…
    Citation: BMC Cancer 2024 24:503
    Content type: Research Published on:

  36. Paclitaxel is commonly used as a second-line therapy for advanced gastric cancer (AGC). The decision to proceed with second-line chemotherapy and select an appropriate regimen is critical for vulnerable patien...

    Authors: Yonghwa Choi, Jangwoo Lee, Keewon Shin, Ji Won Lee, Ju Won Kim, Soohyeon Lee, Yoon Ji Choi, Kyong Hwa Park and Jwa Hoon Kim
    Citation: BMC Cancer 2024 24:502
    Content type: Research Published on:

  37. For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before su...

    Authors: Tongzhen Xu, Lingling Feng, Wenjue Zhang, Haoyue Li, Huiying Ma, Muyasha Abulimiti, Yutong Tan, Feiyan Deng, Wenting Huang, Shuangmei Zou, Wenyan Kang, Liming Jiang, Ying Wang, Chen Hu, Yinggang Chen, Haitao Zhou…
    Citation: BMC Cancer 2024 24:501
    Content type: Study Protocol Published on:

  38. Our aim was to develop a validated Patient Reported Experience Measure (PREM) to capture patient and carer experience during participation in experimental cancer medicine trials (ECM): called PREM-ECM.

    Authors: Chelsea S. Sawyer, Sally Taylor, Louise Carter, Melissa Stanworth, Michelle Davies, Fiona Thistlethwaite, Jo Taylor, Charlotte Eastwood and Janelle Yorke
    Citation: BMC Cancer 2024 24:500
    Content type: Research Published on:

  39. Germline mutations in BRCA1 and BRCA2 genes are among the main causes of hereditary ovarian cancer. Identifying these mutations may reduce cancer risk, facilitate early detection, and enable personalized treat...

    Authors: Caroline de Oliveira Ferreira, Vandré Cabral Gomes Carneiro and Carolline Araujo Mariz
    Citation: BMC Cancer 2024 24:499
    Content type: Research Published on:

  40. Lack of agreed terminology and definitions in healthcare compromises communication, patient safety, optimal management of adverse events, and research progress. The purpose of this scoping review was to unders...

    Authors: Kerrie Curtis, Karla Gough, Meinir Krishnasamy, Elena Tarasenko, Geoff Hill and Samantha Keogh
    Citation: BMC Cancer 2024 24:498
    Content type: Research Published on:

  42. Ferroptosis has important value in cancer treatment. It is significant to explore the new ferroptosis-related lncRNAs prediction model in Hepatocellular carcinoma (HCC) and the potential molecular mechanism of...

    Authors: Ke Zong, Caifeng Lin, Kai Luo, Yilei Deng, Hongfei Wang, Jianfei Hu, Shi Chen and Renfeng Li
    Citation: BMC Cancer 2024 24:496
    Content type: Research Published on:

  43. Although many studies have explored the correlation between quality of life and survival, none have reported this relationship for specific cancers assessed at distinct time points. This meta-analysis aimed to...

    Authors: Taro Okayama, Katsuyoshi Suzuki, Shinichiro Morishita, Junichiro Inoue, Takashi Tanaka, Jiro Nakano and Takuya Fukushima
    Citation: BMC Cancer 2024 24:495
    Content type: Systematic Review Published on:

    The Correction to this article has been published in BMC Cancer 2024 24:529

  44. Informal caregivers (ICs) of patients with cancer provide essential and mainly uncompensated care. A self-perceived preparedness to care for the patient is associated with a lower caregiver burden, described a...

    Authors: Birgitta Johansson, Åsa Cajander, Awais Ahmad, Emma Ohlsson-Nevo, Per Fransson, Brith Granström, Louise von Essen, Ulrica Langegård, Mona Pettersson, Anna Henriksson and Ylva Tiblom Ehrsson
    Citation: BMC Cancer 2024 24:494
    Content type: Study Protocol Published on:

  45. Muscle mass is important for metastatic prostate cancer survival and quality of life (QoL). The backbone of treatment for men with metastatic castration sensitive prostate cancer (mCSPC) is androgen deprivatio...

    Authors: Adriana M Coletta, Lea Haverbeck Simon, Kelsey Maslana, Sarah Taylor, Kish Larson, Pamela A Hansen, Vinay Mathew Thomas, Cornelia M Ulrich, Manish Kohli, Jonathan Chipman, Umang Swami, Sumati Gupta, Benjamin L Maughan and Neeraj Agarwal
    Citation: BMC Cancer 2024 24:493
    Content type: Study Protocol Published on:

  47. This study aimed to systematically analyze the effect of a serine/threonine kinase (STK11) mutation (STK11mut) on therapeutic efficacy and prognosis in patients with non-small cell lung cancer (NSCLC).

    Authors: Ke Xu, Weinan Lu, Airu Yu, Hongwei Wu and Jie He
    Citation: BMC Cancer 2024 24:491
    Content type: Research Published on:

  48. Patients with rheumatologic preexisting autoimmune disease (PAD) have not been enrolled in clinical trials of immune checkpoint inhibitors (ICIs). Therefore, the risks and benefits of ICI therapy in such patie...

    Authors: Xin Liu, Su Li, Liyuan Ke and Hongxia Cui
    Citation: BMC Cancer 2024 24:490
    Content type: Systematic Review Published on:

  49. Authors: Alessio Cirillo, Daniele Marinelli, Umberto Romeo, Daniela Messineo, Francesca De Felice, Marco De Vincentiis, Valentino Valentini, Silvia Mezi, Filippo Valentini, Luca Vivona, Antonella Chiavassa, Bruna Cerbelli, Daniele Santini, Paolo Bossi, Antonella Polimeni, Paolo Marchetti…
    Citation: BMC Cancer 2024 24:487
    Content type: Correction Published on:

    The original article was published in BMC Cancer 2024 24:430

  50. The antiviral drug Nirmatrelvir was found to be a key drug in controlling the progression of pneumonia during the infectious phase of COVID-19. However, there are very few options for effective treatment for c...

    Authors: Xiaoyan Yin, Wanqi Zhu, Xiaoyong Tang, Guangjian Yang, Xianguang Zhao, Kaikai Zhao, Liyang Jiang, Xiaolin Li, Hong Zhao, Xin Wang, Yuanyuan Yan, Ligang Xing, Jinming Yu, Xiangjiao Meng and Hanxi Zhao
    Citation: BMC Cancer 2024 24:486
    Content type: Research Published on:

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