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  1. Breast cancer (BC) poses significant burdens on women globally. While past research suggests a potential link between bone mineral density (BMD) and BC risk, findings remain inconsistent. Our study aims to elu...

    Authors: Ziyang Cheng, Hui Xu, Xin Wang, Tao Teng, Bin Li, Zhong Cao, Zhichao Li, Jiayi Zhang, Jin Xuan, Fengyi Zhang, Yaxin Chen, Yujie Li and Wenbo Wang
    Citation: BMC Cancer 2024 24:1148
    Content type: Research Published on:

  2. Variations in untranslated regions (UTR) alter regulatory pathways impacting phenotype, disease onset, and course of disease. Protein kinase C Zeta (PRKCZ), a serine-threonine kinase, is implicated in cardiova...

    Authors: Aneela Mustafa, Maria Shabbir, Yasmin Badshah, Khushbukhat Khan, Fizzah Abid, Janeen H. Trembley, Tayyaba Afsar, Ali Almajwal and Suhail Razak
    Citation: BMC Cancer 2024 24:1147
    Content type: Research Published on:

  3. The Multidisciplinary Tumor Board (MTB) is a collaborative platform involving specialists in oncology, surgery, radiology, pathology, and radiotherapy, and aims to optimize diagnostics and treatments. Despite ...

    Authors: Rosellina Russo, Tommaso Verdolotti, Alessandro Perna, Luigi Ruscelli, Rosa D’Abronzo, Alberto Romano, Giuseppe Ferrara, Davide Parisi, Amato Infante, Silvia Chiesa, Luca Massimi, Gianpiero Tamburrini, Antonio Ruggiero, Marco Gessi, Matia Martucci and Simona Gaudino
    Citation: BMC Cancer 2024 24:1146
    Content type: Research Published on:

  5. HPV status in a subset of HNSCC is linked with distinct treatment outcomes. Present investigation aims to elucidate the distinct clinicopathological features of HPV-positive and HPV-negative HNSCC and investig...

    Authors: Joni Yadav, Apoorva Chaudhary, Tanya Tripathi, Divya Janjua, Udit Joshi, Nikita Aggarwal, Arun Chhokar, Chetkar Chandra Keshavam, Anna Senrung and Alok Chandra Bharti
    Citation: BMC Cancer 2024 24:1144
    Content type: Research Published on:

  6. F-627 (efbemalenograstim alfa) is a novel long acting granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2) -Fc fragment with a peptide linker. ...

    Authors: Qingyuan Zhang, Zhonghua Wang, Wei Yao, Shufang Wang, Gaochong Zhang, Jianmin Chen, Qingsong Hou, Simon Li, Hongsheng Li, Changsheng Ye, Tao Sun, Hongjian Yang, Zhendong Chen, Zhihong Wang, Xiaoan Liu, Cuizhi Geng…
    Citation: BMC Cancer 2024 24:1143
    Content type: Research Published on:

  7. Colorectal cancer ranks among the most prevalent malignancies globally. Accurate prediction of metachronous liver metastasis is crucial for optimizing postoperative management. Tripartite motif-containing prot...

    Authors: Jiankun Zhu, Shilin Zhi, Jintao Zeng, Shengning Zhou, Yong Ji and Fanghai Han
    Citation: BMC Cancer 2024 24:1142
    Content type: Research Published on:

  8. Curcumin has been reported to have activity for prevention and therapy of CRC, yet its underlying mechanisms remain largely unknown. Recently, emerging evidence suggests that the gut microbiota and its metabol...

    Authors: Wenxin Deng, Xiaojian Xiong, Mingyang Lu, Shibo Huang, Yunfei Luo, Yujie Wang and Ying Ying
    Citation: BMC Cancer 2024 24:1141
    Content type: Research Published on:

  9. In patients with relapsed or refractory neuroblastoma (NB), the limited efficacy of conventional chemotherapies necessitates the exploration of new treatment options. Previous studies have highlighted the anti...

    Authors: Xiaoshan Liu, Xiaomin Peng, Shu Yang, Haijin Liu, Shouhua Zhang, Jinhu Wang, Yuhan Ma, Yu Wu, Zhixuan Wang, Wenjun Weng and Yang Li
    Citation: BMC Cancer 2024 24:1140
    Content type: Research Published on:

  10. MR perfusion is a standard marker to distinguish progression and therapy-associated changes after surgery and radiochemotherapy for glioblastoma. TRAMs (Treatment Response Assessment Maps) were introduced, whi...

    Authors: Eya Khadhraoui, Leon Schmidt, Stefan Klebingat, Roland Schwab, Silvia Hernández-Durán, Georg Gihr, Harald Paukisch, Klaus-Peter Stein, Daniel Behme and Sebastian Johannes Müller
    Citation: BMC Cancer 2024 24:1139
    Content type: Research Published on:

  11. Lung adenocarcinoma (LUAD) significantly contributes to cancer-related mortality worldwide. The heterogeneity of the tumor immune microenvironment in LUAD results in varied prognoses and responses to immunothe...

    Authors: Shengshan Xu, Xiguang Chen, Haoxuan Ying, Jiarong Chen, Min Ye, Zhichao Lin, Xin Zhang, Tao Shen, Zumei Li, Youbin Zheng, Dongxi Zhang, Yongwen Ke, Zhuowen Chen and Zhuming Lu
    Citation: BMC Cancer 2024 24:1138
    Content type: Research Published on:

  12. Exercise is associated with improved survival, physical functioning, treatment tolerability, and quality of life in early-stage breast cancer. These same endpoints matter in metastatic breast cancer (MBC). Pri...

    Authors: Martha A. Cancilla, Donya Nemati, Danielle Halsey, Niraj Shah, Melissa Sherman, Nicholas Kelly, Pengyue Zhang, Nada Kassem, Navin Kaushal, Kelly Shanahan, Lesley Kailani Glenn, Jennifer A. Ligibel and Tarah J. Ballinger
    Citation: BMC Cancer 2024 24:1137
    Content type: Study Protocol Published on:

  13. A variety of solid tumours, including oral squamous cell carcinoma (OSCC), can cause coagulation abnormalities, and this phenomenon is known as tumour-associated hypercoagulation. We aimed to explore the preop...

    Authors: Wan Duan, Zhangxia Wu, Hong Jiang, Guiqing Liao, Yujie Liang and Xiaomei Lao
    Citation: BMC Cancer 2024 24:1136
    Content type: Research Published on:

  15. Crohn’s disease (CD), a prominent manifestation of chronic gastrointestinal inflammation, and breast cancer (BC), seemingly disparate in the medical domain, exhibit a shared characteristic. This convergence ar...

    Authors: Xin Yu, Yushuai Yu, Xiewei Huang, Zirong Jiang, Qing Wang, Xiaoqin Yu and Chuangui Song
    Citation: BMC Cancer 2024 24:1134
    Content type: Research Published on:

  16. Cervical cancer, encompassing squamous cell carcinoma and endocervical adenocarcinoma (CESC), presents a considerable risk to the well-being of women. Recent studies have reported that squalene epoxidase (SQLE...

    Authors: Yue-Chen Zhao, Yun-Feng Li, Ling Qiu, Shun-Zi Jin, Yan-Nan Shen, Chao-He Zhang, Jie Cui and Tie-Jun Wang
    Citation: BMC Cancer 2024 24:1133
    Content type: Research Published on:

  18. Sunitinib, a newly developed multi-targeted tyrosine kinase inhibitor (TKI), has become a common therapeutic option for managing advanced renal cell carcinoma (RCC). Examining the mechanism underlying the inte...

    Authors: Jinyu Hu, Hailun Xia, Xiaohai Chen, Xinhao Xu, Hua-Lu Wu, Yuxin Shen, Ren-ai Xu and Wenzhi Wu
    Citation: BMC Cancer 2024 24:1131
    Content type: Research Published on:

  19. Gastric cancer is one of the most malignant digestive tract tumors worldwide and its progression is associated with gene expression and metabolic alteration. We revealed that the gastric cancer patients with l...

    Authors: Hongjie He, Kexian Dong, Mingming Chen, Yuanyuan Wang, Yawen Li, Dong Wang, Mansha Jia, Xiangning Meng, Wenjing Sun, Songbin Fu and Jingcui Yu
    Citation: BMC Cancer 2024 24:1130
    Content type: Research Published on:

  20. Breast cancer metastasis remains the leading cause of cancer-related deaths in women worldwide. Infiltration of tumor-associated macrophages (TAMs) in the tumor stroma is known to be correlated with reduced ov...

    Authors: Bhawna Deswal, Urmi Bagchi, Manas Kumar Santra, Manoj Garg and Sonia Kapoor
    Citation: BMC Cancer 2024 24:1129
    Content type: Research Published on:

  21. Lung cancer, a major global health concern, disproportionately impacts low socioeconomic status (SES) patients, who face suboptimal care and reduced survival. This study aimed to evaluate the prognostic perfor...

    Authors: Jiaxin Cui, Zifen An, Xiaozhou Zhou, Xi Zhang, Yuying Xu, Yaping Lu and Liping Yu
    Citation: BMC Cancer 2024 24:1128
    Content type: Research Published on:

  22. Survival rates of breast cancer (BC) patients are particularly low in rural regions in sub-Saharan Africa (SSA) which is due to limited access to therapy. In recent years, gene expression profiling (GEP) of BC...

    Authors: Judith Katharina Ballé, Martina Vetter, Tariku Wakuma Kenea, Pia Eber-Schulz, Christian Reibold, Hannes-Viktor Ziegenhorn, Kathrin Stückrath, Claudia Wickenhauser, Adamu Addissie, Pablo Santos, Eva Johanna Kantelhardt, Sefonias Getachew and Marcus Bauer
    Citation: BMC Cancer 2024 24:1127
    Content type: Research Published on:

  23. Lung cancer, particularly non-small cell lung cancer (NSCLC), remains a significant cause of cancer-related mortality, with drug resistance posing a substantial obstacle to effective therapy. LncRNAs have emer...

    Authors: Ruihua Liu, Jiemin Wang, Lichun Zhang, Shu Wang, Xiangnan Li, Yueshi Liu and Haiquan Yu
    Citation: BMC Cancer 2024 24:1126
    Content type: Research Published on:

  24. In the first year of the COVID-19 pandemic, data projections indicated an increase in cancer mortality for the following years due to the overload of health services and the replacement of health priorities. T...

    Authors: Amanda Ramos da Cunha and José Leopoldo Ferreira Antunes
    Citation: BMC Cancer 2024 24:1125
    Content type: Research Published on:

  25. The gut microbiome is thought to play an important role in the development of colorectal cancer (CRC). However, as the gut microbiome varies widely based on diet, we sought to investigate the gut microbiome ch...

    Authors: Bawantha Dilshan Gamage, Diyanath Ranasinghe, AGP Sahankumari and Gathsaurie Neelika Malavige
    Citation: BMC Cancer 2024 24:1124
    Content type: Research Published on:

  26. Bortezomib, lenalidomide, and dexamethasone (VRD), and bortezomib, doxorubicin, and dexamethasone (PAD), are commonly used in induction regimens for patients with newly diagnosed multiple myeloma (NDMM) in Chi...

    Authors: Dong Liang, Shenrui Bai, Demei Feng, Guanjun Chen, Yang Liang and Hua Wang
    Citation: BMC Cancer 2024 24:1123
    Content type: Research Published on:

  28. Nonresectable gastric cancer develops rapidly; thus, monitoring disease progression especially in patients receiving nivolumab as late-line therapy is important. Biomarkers may facilitate the evaluation of niv...

    Authors: Michiko Inukai, Tomohiko Nishi, Hiroshi Matsuoka, Kazuhiro Matsuo, Kazumitsu Suzuki, Akiko Serizawa, Shingo Akimoto, Masaya Nakauchi, Tsuyoshi Tanaka, Kenji Kikuchi, Susumu Shibasaki, Ichiro Uyama and Koichi Suda
    Citation: BMC Cancer 2024 24:1121
    Content type: Research Published on:

  29. Transcatheter arterial chemoembolization (TACE) combined with targeted therapy and immunotherapy can significantly improve the prognosis of patients with hepatocellular carcinoma (HCC). T-cell immunoreceptor w...

    Authors: Yuan Guo, Xiong Yang, Wei Li Xia, Wen Bo Zhu, Fang Ting Li, Hong Tao Hu and Hai Liang Li
    Citation: BMC Cancer 2024 24:1120
    Content type: Research Published on:

  32. Gastric cancer (GC) ranks among the prevalent types of cancer, and its progression is influenced by the tumor microenvironment (TME). A comprehensive comprehension of the TME associated with GC has the potenti...

    Authors: Dapeng Chen, Wen Tong, Bing Ang, Yi Bai, Wenhui Dong, Xiyue Deng, Chunjiong Wang and Yamin Zhang
    Citation: BMC Cancer 2024 24:1117
    Content type: Research Published on:

  34. Nasopharyngeal carcinoma (NPC) is diagnosed relatively late and has a poor prognosis, requiring early detection to reduce the disease burden. This diagnostic test accuracy meta-analysis evaluated the serologic...

    Authors: Han Liu, Lin Lei, Song Song, Xianyi Geng, Kaihao Lin, Ni Li, Wanqing Chen, Ji Peng and Jiansong Ren
    Citation: BMC Cancer 2024 24:1115
    Content type: Research Published on:

  35. Lung cancer is one of the most common cancers and causes of cancer death in Canada. Some previous literature suggests that socioeconomic inequalities in lung cancer screening, treatment and survival may exist....

    Authors: Arlinda Ruco, Aisha K. Lofters, Hong Lu, Nancy N. Baxter, Sara Guilcher, Alexander Kopp, Mandana Vahabi and Geetanjali D. Datta
    Citation: BMC Cancer 2024 24:1114
    Content type: Research Published on:

  36. This meta-analysis aims to clarify the association between the TNF-α -308G > A and − 238G > A polymorphisms and lung cancer risk.

    Authors: Seyed Masoud HaghighiKian, Ahmad Shirinzadeh-Dastgiri, Reza Ershadi, Mohammad Vakili-Ojarood, Maedeh Barahman, Seyed Alireza Dastgheib, Fatemeh Asadian, Amirmasoud Shiri, Maryam Aghasipour, Amirhossein Rahmani, Kazem Aghili and Hossein Neamatzadeh
    Citation: BMC Cancer 2024 24:1113
    Content type: Research Published on:

  37. Hepatocellular carcinoma (HCC), a prevalent primary malignant tumor, is notorious for its high mortality rate. Despite advancements in HCC treatment, patient outcomes remain suboptimal. This study endeavors to...

    Authors: Yan Dong, Xinyi Chen, Shen Yang, Yilong Fu, Liangyu Wang, Xueping Gao, Di Chen and Lixia Xu
    Citation: BMC Cancer 2024 24:1112
    Content type: Research Published on:

  38. Risk-stratified approaches to breast screening show promise for increasing benefits and reducing harms. But the successful implementation of such an approach will rely on public acceptability. To date, researc...

    Authors: Charlotte Kelley-Jones, Suzanne E. Scott and Jo Waller
    Citation: BMC Cancer 2024 24:1111
    Content type: Research Published on:

  39. The prognosis of patients with hepatocellular cancer is substantially correlated with the abnormal expression of growing long non-coding RNA small nucleolar host gene RNA (SNHG) families in liver cancer tissue...

    Authors: Sheng-qi Du, Ya-Tong Liu, Fen Yang, Pei-xue Wang and Jun Zhang
    Citation: BMC Cancer 2024 24:1110
    Content type: Systematic Review Published on:

  40. Meaningful engagement with stakeholders in research demands intentional approaches. This paper describes the development of a framework to guide stakeholder engagement as research partners in a pragmatic trial...

    Authors: Cameron Macdonald, Margaret Fitch, Katherine A. Hutcheson, Timothy M. McCulloch and Rosemary Martino
    Citation: BMC Cancer 2024 24:1109
    Content type: Comment Published on:

  41. Patients with head and neck cancers (HNC) experience many transitions in care (TiC), occurring when patients are transferred between healthcare providers and/or settings. TiC can compromise patient safety, dec...

    Authors: Jaling Kersen, Pamela Roach, Shamir Chandarana, Paul Ronksley and Khara Sauro
    Citation: BMC Cancer 2024 24:1108
    Content type: Research Published on:

  42. Women with breast cancer face many barriers to return to work (RTW) after their cancer. The main objective of the FASTRACS-RCT is to evaluate the impact of the FASTRACS (Facilitate and Sustain Return to Work a...

    Authors: Jean-Baptiste Fassier, Laure Guittard, Béatrice Fervers, Sabrina Rouat, Philippe Sarnin, Julien Carretier, Guillaume Broc, Laurent Letrilliart, Julien Péron and Marion Lamort-Bouché
    Citation: BMC Cancer 2024 24:1107
    Content type: Study Protocol Published on:

  43. This study aims to investigate preoperative prognostic factors available for intrahepatic cholangiocarcinoma (ICC) patients and propose a new preoperative prognostic scoring system for ICC that combines CA19-9...

    Authors: Shilei Bai, Xiaodong Shi, Yizhe Dai, Huifeng Wang, Yong Xia, Jian Liu and Kui Wang
    Citation: BMC Cancer 2024 24:1106
    Content type: Research Published on:

  44. SEPT9 is a pivotal cytoskeletal GTPase that regulates diverse biological processes encompassing mitosis and cytokinesis. While previous studies have implicated SEPT9 in tumorigenesis and development; comprehensiv...

    Authors: Wenwen Wang, Xiaochen Zhang, Ping Gui, Qizhen Zou, Yuzhou Nie, Shenglin Ma and Shirong Zhang
    Citation: BMC Cancer 2024 24:1105
    Content type: Research Published on:

  45. The purpose of this retrospective study was to compare the safety and feasibility of single-intercostal totally minimally invasive Ivor Lewis esophagectomy (MIIE) with those of multiple-intercostal MIIE.

    Authors: Jinghao Huang, Yifan Yu, Zixiang Wu, Chuanqiang Wu, Jinsheng Li, Zhiling Lou and Ming Wu
    Citation: BMC Cancer 2024 24:1104
    Content type: Research Published on:

  46. Cisplatin (CDDP) remains a key agent in the treatment of muscle-infiltrating bladder carcinoma (MIBC). However, a proportion of MIBC patients do not respond to chemotherapy, which may be caused by the increase...

    Authors: Patrik Palacka, Andrea Holíčková, Jan Roška, Peter Makovický, Miroslava Vallová, Csaba Biró, Eveline Órásová, Jana Obertová, Jozef Mardiak, Thomas A. Ward, Karol Kajo and Miroslav Chovanec
    Citation: BMC Cancer 2024 24:1103
    Content type: Research Published on:

  47. According to GLOBOCAN 2020 Breast cancer is the most common cancer among women and the prevalence is increasing worldwide and in Ethiopia. This review assessed studies conducted in Ethiopia on the clinical fea...

    Authors: Firaol Guyassa Dandena, Berhanetsehay Teklemariam Teklewold, Tadele Dana Darebo and Yisihak Debodina Suga
    Citation: BMC Cancer 2024 24:1102
    Content type: Systematic Review Published on:

  48. Neoadjuvant chemoradiotherapy (nCRT) followed by surgery remains a standard of care for resectable esophageal cancer (EC), and definitive chemoradiotherapy (dCRT) is an alternative for unresectable diseases. H...

    Authors: Jiacheng Yao, Xinyu Zhao, Jun Chen, Tingting Liu, Yaowen Song and Jun Dang
    Citation: BMC Cancer 2024 24:1101
    Content type: Research Published on:

  49. Glioblastoma multiforme (GBM) is the most malignant brain tumor, with a poor prognosis and life expectancy of 14–16 months after diagnosis. The standard treatment for GBM consists of surgery, radiotherapy, and...

    Authors: Nastaran Afsordeh, Safura Pournajaf, Hadi Bayat, Fatemeh Mohajerani, Amir Shojaei, Javad Mirnajafi-Zadeh and Mohammad Hossein Pourgholami
    Citation: BMC Cancer 2024 24:1099
    Content type: Research Published on:

  50. Liver cancer (LC) is frequently preceded by cirrhosis and poses a significant public health challenge in the United States (US). Recent decades have seen notable shifts in the epidemiological patterns of LC, y...

    Authors: Omar Al Ta’ani, Yazan Al-Ajlouni, Balaji Jagdish, Himsikhar Khataniar, Wesam Aleyadeh, Farah Al-Bitar and Tavankit Singh
    Citation: BMC Cancer 2024 24:1098
    Content type: Research Published on:

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