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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. Extranodal natural killer/T-cell lymphoma (NKTCL), nasal type, is an aggressive malignancy with poor prognosis. Currently, there is no recommended standard therapy for relapsed NKTCL.

    Authors: Jianping Lai, Peng Xu, Xiaoliu Jiang, Shan Zhou and Anwen Liu
    Citation: BMC Cancer 2017 17:507
    Content type: Case report Published on:

  2. CHD5 is a conventional tumour-suppressing gene in many tumours. The aim of this study was to determine whether CHD5 variants contribute to the risk of hepatocellular carcinoma (HCC).

    Authors: Qin Xiao, Lianzhou Chen, Haiqing Luo, Hongmei Li, Qingming Kong, Fei Jiao, Shifeng Pang, Ming Zhang, Feifei Lan, Wenguo Fan, Hui Luo, Tao Tao and Xiao Zhu
    Citation: BMC Cancer 2018 18:658
    Content type: Research article Published on:

  3. HDGF is a growth factor which is overexpressed in a wide range of tumors. Importantly, expression levels were identified as a prognostic marker in some types of cancer such as melanoma.

    Authors: Angela Sedlmaier, Nicolas Wernert, Rainer Gallitzendörfer, Mekky M Abouzied, Volkmar Gieselmann and Sebastian Franken
    Citation: BMC Cancer 2011 11:457
    Content type: Research article Published on:

  4. Many cancers preferentially meet their energy requirements through the glycolytic pathway rather than via the more efficient oxidative phosphorylation pathway. It is thought that this is an important adaptatio...

    Authors: Danielle J Smith, Luke R Cossins, Irene Hatzinisiriou, Michelle Haber and Phillip Nagley
    Citation: BMC Cancer 2008 8:259
    Content type: Research article Published on:

  5. Angiogenesis is a proliferative process resulting in the development of new blood vessels from existing endothelial cells and is considered crucial for tumor growth and metastasis. Tumor angiogenesis can be qu...

    Authors: Juliana Passos Paschoal, Vagner Bernardo, Nathalie Henriques Silva Canedo, Osmar Damasceno Ribeiro, Adriana Caroli-Bottino and Vera Lucia Pannain
    Citation: BMC Cancer 2014 14:72
    Content type: Research article Published on:

  6. PANoptosis is a specific type of inflammatory programmed cell death (PCD) modality that can be involved in three key modes of cellular programmed cell death-pyroptosis, apoptosis and necroptosis. We analyzed P...

    Authors: Yan Xu, Jingqi Hua, Hongliang Que, Tengyue Zeng, Quan Li, Junpeng Deng and Jianjun Xie
    Citation: BMC Cancer 2024 24:292
    Content type: Research Published on:

  7. While the treatment guidelines have been established for pure urothelial carcinoma (pUC), patients with variant type urothelial carcinoma (vUC) face limited effective treatment options. The effectiveness of im...

    Authors: Tsung-Han Tsai, Po-Jung Su, Shih-Yu Huang, Ming-Chun Kuo, Chang-Ting Lin, Chia-Che Wu, Hao-Lun Luo, Chien-Hsu Chen, Chih-Chi Chou, Ting-Ting Liu, Chun-Chieh Huang, Kai-Lung Tsai and Yu-Li Su
    Citation: BMC Cancer 2023 23:871
    Content type: Research Published on:

  9. Hepatocellular carcinoma (HCC) is a lethal disease, while the precise underlying molecular mechanisms of HCC pathogenesis remain to be defined. MicroRNA (miRNA), a class of non-coding small RNAs, can post-tran...

    Authors: Qiao Zhu, Li Gong, Jun Wang, Qian Tu, Li Yao, Jia-Rui Zhang, Xiu-Juan Han, Shao-Jun Zhu, Shu-Mei Wang, Yan-Hong Li and Wei Zhang
    Citation: BMC Cancer 2016 16:806
    Content type: Research article Published on:

  10. Vitronectin is a multifunctional glycoprotein known in several human tumors for its adhesive role in processes such as cell growth, angiogenesis and metastasis. In this study, we examined vitronectin expressio...

    Authors: Rebeca Burgos-Panadero, Inmaculada Noguera, Adela Cañete, Samuel Navarro and Rosa Noguera
    Citation: BMC Cancer 2019 19:479
    Content type: Research article Published on:

  11. Esophageal squamous cell carcinoma (ESCC) is an aggressive cancer with one of the highest world incidences in the Eastern Cape region of South Africa. Several genome wide studies have been performed on ESCC co...

    Authors: Jacqueline Brown, Andrzej J. Stepien and Pascale Willem
    Citation: BMC Cancer 2020 20:281
    Content type: Research article Published on:

  12. To investigate whether PET/CT-guided bone marrow biopsy adds complementary information for evaluation of bone marrow involvement (BMI) in newly diagnosed lymphomas.

    Authors: Bing Hao, Long Zhao, Na-na Luo, Dan Ruan, Yi-zhen Pang, Wei Guo, Hao Fu, Xiu-yu Guo, Zuo-ming Luo, Jing Wu, Hao-jun Chen, Hua Wu and Long Sun
    Citation: BMC Cancer 2018 18:1192
    Content type: Research article Published on:

  14. Extraneural metastases (ENM) rarely occur in medulloblastoma (MBL) patients and only few cases of subcutaneous localizations have been described. ENM indicate an aggressive disease associated with a worse prog...

    Authors: Angela Mastronuzzi, Evelina Miele, Agnese Po, Manila Antonelli, Francesca Romana Buttarelli, Giovanna Stefania Colafati, Francesca del Bufalo, Roberta Faedda, Gian Paolo Spinelli, Andrea Carai, Felice Giangaspero, Alberto Gulino, Franco Locatelli and Elisabetta Ferretti
    Citation: BMC Cancer 2014 14:262
    Content type: Case report Published on:

  15. The aim of the trial is to demonstrate that with the use of modern IMRT/IGRT and reduction of safety margins postoperative wound complications can be reduced.

    Authors: Barbara Röper, Christine Heinrich, Victoria Kehl, Hans Rechl, Katja Specht, Klaus Wörtler, Andreas Töpfer, Michael Molls, Severin Kampfer, Rüdiger von Eisenharth-Rothe and Stephanie E. Combs
    Citation: BMC Cancer 2015 15:904
    Content type: Study protocol Published on:

  16. Differentiating true glioblastoma multiforme (GBM) from pseudoprogression (PsP) remains a challenge with current standard magnetic resonance imaging (MRI). The objective of this study was to explore whether pa...

    Authors: Jing Xi, Bilal Hassan, Ruth G. N. Katumba, Karam Khaddour, Akshay Govindan, Jingqin Luo, Jiayi Huang and Jian L. Campian
    Citation: BMC Cancer 2021 21:285
    Content type: Research article Published on:

  17. Whole brain radiation therapy (WBRT) is the standard therapy for multiple brain metastases. However, WBRT has a poor local tumor control and is associated with a decline in neurocognitive function (NCF). Aim o...

    Authors: Anca-Ligia Grosu, Lars Frings, Iryna Bentsalo, Oliver Oehlke, Franziska Brenner, Angelika Bilger, Jamina Tara Fennell, Thomas Rothe, Sabine Schneider-Fuchs, Erika Graf, Claudia Schmoor, Jürgen Beck, Gerhild Becker, Michael Bock, Karl Egger, Horst Urbach…
    Citation: BMC Cancer 2020 20:532
    Content type: Study protocol Published on:

  18. Treatment options for patients with advanced hepatocellular carcinoma (HCC) are often limited. In most cases, they are not amenable to local therapies including surgery or radiofrequency ablation. The multi-ki...

    Authors: Stephanie E Combs, Daniel Habermehl, Tom Ganten, Jan Schmidt, Lutz Edler, Iris Burkholder, Oliver Jäkel, Thomas Haberer and Jürgen Debus
    Citation: BMC Cancer 2011 11:67
    Content type: Study protocol Published on:

  19. Several efforts have been focused on identification of pathways involved in malignancy, progression, and response to treatment in Glioblastoma (GB). Overexpression of PKCε was detected in histological samples ...

    Authors: Ewa Toton, Aleksandra Romaniuk, Natalia Konieczna, Johann Hofmann, Jan Barciszewski and Maria Rybczynska
    Citation: BMC Cancer 2018 18:185
    Content type: Research article Published on:

  20. A more effective immune response against glioblastoma is needed in order to achieve better tumor control. Radiotherapy can induce anti-tumor mediated immune reactions, in addition to its dose response effects....

    Authors: Emma Liljedahl, Elise Konradsson, Emma Gustafsson, Karolina Förnvik Jonsson, Jill K. Olofsson, Kurt Osther, Crister Ceberg and Henrietta Nittby Redebrandt
    Citation: BMC Cancer 2023 23:106
    Content type: Research Published on:

  21. As the important suppressor of P53, iASPP is found to be overexpressed in leukemia, and functions as oncogene that inhibited apoptosis of leukemia cells. Sertad1 is identified as one of the proteins that can b...

    Authors: Shaowei Qiu, Shuang Liu, Tengteng Yu, Jing Yu, Min Wang, Qing Rao, Haiyan Xing, Kejing Tang, Yinchang Mi and Jianxiang Wang
    Citation: BMC Cancer 2017 17:795
    Content type: Research article Published on:

  22. Distinct characteristic features categorize Merkel cell carcinoma (MCC) into two subgroups according to the Merkel cell polyomavirus infection. Many mutational studies on MCC have been carried out in recent ye...

    Authors: Tuukka Veija, Virve Koljonen, Tom Bohling, Mia Kero, Sakari Knuutila and Virinder Kaur Sarhadi
    Citation: BMC Cancer 2017 17:236
    Content type: Research article Published on:

  23. Currently, the choice of treatment for individuals with metastatic soft tissue sarcomas (MSTS) presents a significant challenge to clinicians. The aim of this retrospective study was to assess the efficacy and...

    Authors: Yaolin Chen, Xiangzhen Liu, Jijun Liu, Donghua Liang, Mingdong Zhao, Weiguang Yu and Pengfei Chen
    Citation: BMC Cancer 2021 21:108
    Content type: Research article Published on:

  24. Tumour cells have a high demand for arginine. However, a subset of glioblastomas has a defect in the arginine biosynthetic pathway due to epigenetic silencing of the rate limiting enzyme argininosuccinate synt...

    Authors: Lina Mörén, Richard Perryman, Tim Crook, Julia K. Langer, Kevin Oneill, Nelofer Syed and Henrik Antti
    Citation: BMC Cancer 2018 18:167
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Cancer 2018 18:268

  25. Many patients experience local recurrence or metastases after receiving potentially curative treatment, and early detection of these events is important for disease control. Recent technological advances make ...

    Authors: Heidi M. Namløs, Olga Zaikova, Bodil Bjerkehagen, Daniel Vodák, Eivind Hovig, Ola Myklebost, Kjetil Boye and Leonardo A. Meza-Zepeda
    Citation: BMC Cancer 2017 17:29
    Content type: Case report Published on:

  27. Patients with metastatic renal carcinoma frequently have pre-existing renal impairment and not infrequently develop worsening renal function as a complication of their treatment. The presence of pancreatic met...

    Authors: Karin Purshouse, Sarah Chamberlain, Maria Soares, Mark Tuthill, Andrew Protheroe and David R. Mole
    Citation: BMC Cancer 2019 19:967
    Content type: Case report Published on:

  28. Acute myeloid leukemia (AML) accounts for more than two thirds of leukemia during pregnancy and has an incidence of 1 in 75,000 to 100,000. Its clinical management remains a challenging therapeutic task both f...

    Authors: Nicola Stefano Fracchiolla, Mariarita Sciumè, Francesco Dambrosi, Francesca Guidotti, Manuela Wally Ossola, Giovanna Chidini, Umberto Gianelli, Daniela Merlo and Agostino Cortelezzi
    Citation: BMC Cancer 2017 17:442
    Content type: Research article Published on:

  29. Cell adhesion-mediated drug resistance (CAM-DR) is a major clinical problem that prevents successful treatment of multiple myeloma (MM). In particular, the expression levels of integrin β1 and its sub-cellular...

    Authors: Yuejiao Huang, Xianting Huang, Chun Cheng, Xiaohong Xu, Hong Liu, Xiaojing Yang, Li Yao, Zongmei Ding, Jie Tang, Song He and Yuchan Wang
    Citation: BMC Cancer 2019 19:1269
    Content type: Research article Published on:

  30. Chronic Myeloid Leukemia was always referred as a unique cancer due to the apparent independence from tumor suppressors’ deletions/mutations in the early stages of the disease. However, it is now well document...

    Authors: Sabrina Crivellaro, Giovanna Carrà, Cristina Panuzzo, Riccardo Taulli, Angelo Guerrasio, Giuseppe Saglio and Alessandro Morotti
    Citation: BMC Cancer 2016 16:314
    Content type: Review Published on:

  31. Antiangiogenesis is a promising therapy for advanced hepatocellular carcinoma (HCC), but the effects are difficult to be evaluated. Pazopanib (GW786034B) is a pan-vascular endothelial growth factor receptor in...

    Authors: Xiao-Dong Zhu, Ju-Bo Zhang, Pei-Li Fan, Yu-Quan Xiong, Peng-Yuan Zhuang, Wei Zhang, Hua-Xiang Xu, Dong-Mei Gao, Ling-Qun Kong, Lu Wang, Wei-Zhong Wu, Zhao-You Tang, Hong Ding and Hui-Chuan Sun
    Citation: BMC Cancer 2011 11:28
    Content type: Research article Published on:

  33. We sought to understand the clinical course and molecular phenotype of patients who showed disease progression after programmed cell death ligand 1 (PD-L1) inhibitor treatment but subsequently responded to PD-...

    Authors: Xi Chen, Haiying Kong, Linxiang Luo, Shuiyun Han, Tao Lei, Haifeng Yu, Na Guo, Cong Li, Shuailing Peng, Xiaowu Dong, Haiyan Yang and Meijuan Wu
    Citation: BMC Cancer 2022 22:9
    Content type: Research Published on:

  34. While data from several studies over the last decade has demonstrated that introduction of immunologic checkpoint blockage therapy with anti-CTLA-4/PD-1 drugs leads to improved survival in metastatic melanoma ...

    Authors: Marin A. McDonald, Parag Sanghvi, Julie Bykowski and Gregory A. Daniels
    Citation: BMC Cancer 2018 18:549
    Content type: Case report Published on:

  36. Follicular thyroid carcinoma (FTC) metastasis to the facial skeleton is exceedingly rare. A case of FTC metastasizing to the mandible is presented and a systematic review of the literature describing thyroid m...

    Authors: Varun V. Varadarajan, Elizabeth K. Pace, Vatsal Patel, Raja Sawhney, Robert J. Amdur and Peter T. Dziegielewski
    Citation: BMC Cancer 2017 17:225
    Content type: Case report Published on:

  37. Pleomorphic liposarcoma (PLPS) is a rare, heterogeneous and an aggressive variant of liposarcoma. Therefore, individualized therapy is urgently needed. Our recent reports suggest that trabectedin (TRAB) is eff...

    Authors: Tasuku Kiyuna, Yasunori Tome, Takashi Murakami, Kei Kawaguchi, Kentaro Igarashi, Kentaro Miyake, Masuyo Miyake, Yunfeng Li, Scott D. Nelson, Sarah M. Dry, Arun S. Singh, Tara A. Russell, Irmina Elliott, Shree Ram Singh, Fuminori Kanaya, Fritz C. Eilber…
    Citation: BMC Cancer 2018 18:840
    Content type: Research article Published on:

  38. Median survival of metastatic malignant melanoma is 6.0 to 7.5 months, with a 5-year survival of ~6.0%. Although long-term complete remissions are rare, few reports describe cases after chemotherapy. Fifty-thr...

    Authors: Xavier Durando, Emilie Thivat, Michel D'Incan, Anne Sinsard, Jean-Claude Madelmont and Philippe Chollet
    Citation: BMC Cancer 2005 5:147
    Content type: Case report Published on:

  39. Acute promyelocytic leukaemia (APL) is a unique subtype of acute myeloid leukaemia (AML) characterized by haematopoietic failure caused by the accumulation of abnormal promyelocytic cells in bone marrow (BM). ...

    Authors: Guiran Wang, Guiling Yan, Kanru Sang, Huijie Yang, Ni Sun, Yuanyuan Bai, Feng Xu, Xiaoqun Zheng and Zhanguo Chen
    Citation: BMC Cancer 2022 22:481
    Content type: Research Published on:

  40. We report here a correlation analysis conducted along with a phase II trial assessing bevacizumab in combination with weekly paclitaxel.

    Authors: Loïc Lebellec, François Bertucci, Emmanuelle Tresch-Bruneel, Isabelle Ray-Coquard, Axel Le Cesne, Emmanuelle Bompas, Jean-Yves Blay, Antoine Italiano, Olivier Mir, Thomas Ryckewaert, Yves Toiron, Luc Camoin, Anthony Goncalves, Nicolas Penel and Marie-Cécile Le Deley
    Citation: BMC Cancer 2018 18:963
    Content type: Research article Published on:

  41. Response evaluation of neoadjuvant chemotherapy (NACT) in patients with osteosarcoma is significant for the termination of ineffective treatment, the development of postoperative chemotherapy regimens, and the...

    Authors: Bingsheng Huang, Jifei Wang, Meili Sun, Xin Chen, Danyang Xu, Zi-Ping Li, Jinting Ma, Shi-Ting Feng and Zhenhua Gao
    Citation: BMC Cancer 2020 20:322
    Content type: Research article Published on:

  42. Patients with dedifferentiated or anaplastic thyroid carcinomas currently lack appropriate treatment options. Kinase inhibitors are among the most promising new agents as alternative strategies. The BRAF- and ...

    Authors: Martina Broecker-Preuss, Stefan Müller, Martin Britten, Karl Worm, Kurt Werner Schmid, Klaus Mann and Dagmar Fuhrer
    Citation: BMC Cancer 2015 15:184
    Content type: Research article Published on:

  43. Retinoblastoma (Rb) is the most common primary intraocular tumor in children. Local treatment of the intraocular disease is usually effective if diagnosed early; however advanced Rb can metastasize through rou...

    Authors: Anderson H. Webb, Bradley T. Gao, Zachary K. Goldsmith, Andrew S. Irvine, Nabil Saleh, Ryan P. Lee, Justin B. Lendermon, Rajini Bheemreddy, Qiuhua Zhang, Rachel C. Brennan, Dianna Johnson, Jena J. Steinle, Matthew W. Wilson and Vanessa M. Morales-Tirado
    Citation: BMC Cancer 2017 17:434
    Content type: Research article Published on:

  45. To evaluate the role of ablative radiotherapy doses in the treatment of hilar or intrahepatic cholangiocarcinoma (CCC) using stereotactic body radiotherapy (SBRT).

    Authors: Eleni Gkika, Lukas Hallauer, Simon Kirste, Sonja Adebahr, Nico Bartl, Hannes Philipp Neeff, Ralph Fritsch, Volker Brass, Ursula Nestle, Anca Ligia Grosu and Thomas Baptist Brunner
    Citation: BMC Cancer 2017 17:781
    Content type: Research article Published on:

  46. Little data exists predicting the resistance to actinomycin D (Act-D) single-agent for gestational trophoblastic neoplasia (GTN). The objective was to determine the overall success of pulse Act-D and the facto...

    Authors: Lei Li, Xirun Wan, Fengzhi Feng, Tong Ren, Junjun Yang, Jun Zhao, Fang Jiang and Yang Xiang
    Citation: BMC Cancer 2018 18:585
    Content type: Research article Published on:

  47. Gastric carcinoma remains the second commonest cause of cancer deaths worldwide. Presence of the carcinoma cell in the pulmonary artery is serious condition that might cause remodeling of the pulmonary artery....

    Authors: Takao Ishiwatari, Yoichiro Okubo, Naobumi Tochigi, Megumi Wakayama, Tetsuo Nemoto, Junko Kobayashi, Minoru Shinozaki, Kyoko Aki, Daisuke Sasai, Yoshiro Yamamoto, Haruo Nakayama and Kazutoshi Shibuya
    Citation: BMC Cancer 2014 14:14
    Content type: Research article Published on:

  48. Glucose-6-phosphate dehydrogenase (G6PD), elevated in tumor cells, catalyzes the first reaction in the pentose-phosphate pathway. The regulation mechanism of G6PD and pathological change in human melanoma grow...

    Authors: Tao Hu, Chunhua Zhang, Qiongling Tang, Yanan Su, Bo Li, Long Chen, Zheng Zhang, Tianchi Cai and Yuechun Zhu
    Citation: BMC Cancer 2013 13:251
    Content type: Research article Published on:

  49. The intermediate filament forming protein keratin 8 (K8) is a tumour-associated antigen, which was shown to be over-expressed in a variety of malignancies. Here, we present a study of K8 expression in squamous...

    Authors: Christoph Matthias, Brigitte Mack, Alexander Berghaus and Olivier Gires
    Citation: BMC Cancer 2008 8:267
    Content type: Research article Published on:

  50. Osteosarcoma strikes hundreds of people each year, of both advanced and younger ages, and is often terminal. Like many tumor types, these bone tumors will frequently undergo a neuroendocrine transition, utiliz...

    Authors: Marcus A. Weinman, Jacob A. Fischer, Dakota C. Jacobs, Cheri P. Goodall, Shay Bracha and Patrick E. Chappell
    Citation: BMC Cancer 2019 19:158
    Content type: Research article Published on:

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