Maris JM, Hogarty MD, Bagatell R, Cohn SL: Neuroblastoma. Lancet. 2007, 369 (9579): 2106-2120. 10.1016/S0140-6736(07)60983-0.
Article
CAS
PubMed
Google Scholar
Schwab M, Alitalo K, Klempnauer KH, Varmus HE, Bishop JM, Gilbert F, Brodeur G, Goldstein M, Trent J: Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature. 1983, 305 (5931): 245-248. 10.1038/305245a0.
Article
CAS
PubMed
Google Scholar
Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM: Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science. 1984, 224 (4653): 1121-1124. 10.1126/science.6719137.
Article
CAS
PubMed
Google Scholar
Ibson JM, Rabbitts PH: Sequence of a germ-line N-myc gene and amplification as a mechanism of activation. Oncogene. 1988, 2 (4): 399-402.
CAS
PubMed
Google Scholar
Norris MD, Burkhart CA, Marshall GM, Weiss WA, Haber M: Expression of N-myc and MRP genes and their relationship to N-myc gene dosage and tumor formation in a murine neuroblastoma model. Med Pediatr Oncol. 2000, 35 (6): 585-589. 10.1002/1096-911X(20001201)35:6<585::AID-MPO20>3.0.CO;2-P.
Article
CAS
PubMed
Google Scholar
Weiss WA, Aldape K, Mohapatra G, Feuerstein BG, Bishop JM: Targeted expression of MYCN causes neuroblastoma in transgenic mice. Embo J. 1997, 16 (11): 2985-2995. 10.1093/emboj/16.11.2985.
Article
CAS
PubMed
PubMed Central
Google Scholar
Weiss WA, Godfrey T, Francisco C, Bishop JM: Genome-wide screen for allelic imbalance in a mouse model for neuroblastoma. Cancer Res. 2000, 60 (9): 2483-2487.
CAS
PubMed
Google Scholar
Crooke ST: Potential roles of antisense technology in cancer chemotherapy. Oncogene. 2000, 19 (56): 6651-6659. 10.1038/sj.onc.1204093.
Article
CAS
PubMed
Google Scholar
Burkhart CA, Cheng AJ, Madafiglio J, Kavallaris M, Mili M, Marshall GM, Weiss WA, Khachigian LM, Norris MD, Haber M: Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma. J Natl Cancer Inst. 2003, 95 (18): 1394-1403.
Article
PubMed
Google Scholar
Tang XX, Zhao H, Kung B, Kim DY, Hicks SL, Cohn SL, Cheung NK, Seeger RC, Evans AE, Ikegaki N: The MYCN enigma: significance of MYCN expression in neuroblastoma. Cancer Res. 2006, 66 (5): 2826-2833. 10.1158/0008-5472.CAN-05-0854.
Article
CAS
PubMed
Google Scholar
Cohn SL, London WB, Huang D, Katzenstein HM, Salwen HR, Reinhart T, Madafiglio J, Marshall GM, Norris MD, Haber M: MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN. J Clin Oncol. 2000, 18 (21): 3604-3613.
CAS
PubMed
Google Scholar
Bordow SB, Norris MD, Haber PS, Marshall GM, Haber M: Prognostic significance of MYCN oncogene expression in childhood neuroblastoma. J Clin Oncol. 1998, 16 (10): 3286-3294.
CAS
PubMed
Google Scholar
Warburg O, Wind F, Negelein E: Uber den Stoffwechsel von Tumouren im Korper. Klin Woch. 1926, 5: 829-832. 10.1007/BF01726240.
Article
CAS
Google Scholar
Kushner BH, Yeung HW, Larson SM, Kramer K, Cheung NK: Extending positron emission tomography scan utility to high-risk neuroblastoma: fluorine-18 fluorodeoxyglucose positron emission tomography as sole imaging modality in follow-up of patients. J Clin Oncol. 2001, 19 (14): 3397-3405.
CAS
PubMed
Google Scholar
Gatenby RA, Gillies RJ: Why do cancers have high aerobic glycolysis?. Nat Rev Cancer. 2004, 4 (11): 891-899. 10.1038/nrc1478.
Article
CAS
PubMed
Google Scholar
Boon K, Caron HN, van Asperen R, Valentijn L, Hermus MC, van Sluis P, Roobeek I, Weis I, Voute PA, Schwab M, et al: N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO Journal. 2001, 20 (6): 1383-1393. 10.1093/emboj/20.6.1383.
Article
CAS
PubMed
PubMed Central
Google Scholar
Biedler JL, Spengler BA: A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture. J Natl Cancer Inst. 1976, 57 (3): 683-695.
CAS
PubMed
Google Scholar
Rosen N, Reynolds CP, Thiele CJ, Biedler JL, Israel MA: Increased N-myc expression following progressive growth of human neuroblastoma. Cancer Res. 1986, 46 (8): 4139-4142.
CAS
PubMed
Google Scholar
Marshall GM, Cheung B, Stacey KP, Camacho ML, Simpson AM, Kwan E, Smith S, Haber M, Norris MD: Increased retinoic acid receptor gamma expression suppresses the malignant phenotype and alters the differentiation potential of human neuroblastoma cells. Oncogene. 1995, 11 (3): 485-491.
CAS
PubMed
Google Scholar
Ross RA, Spengler BA, Biedler JL: Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J Natl Cancer Inst. 1983, 71 (4): 741-747.
CAS
PubMed
Google Scholar
Sadee W, Yu VC, Richards ML, Preis PN, Schwab MR, Brodsky FM, Biedler JL: Expression of neurotransmitter receptors and myc protooncogenes in subclones of a human neuroblastoma cell line. Cancer Research. 1987, 47 (19): 5207-5212.
CAS
PubMed
Google Scholar
Biedler JL, Spengler BA, Chang TD, Ross RA: Transdifferentiation of human neuroblastoma cells results in coordinate loss of neuronal and malignant properties. Prog Clin Biol Res. 1988, 271: 265-276.
CAS
PubMed
Google Scholar
Cohn SL, Salwen H, Quasney MW, Ikegaki N, Cowan JM, Herst CV, Kennett RH, Rosen ST, DiGiuseppe JA, Brodeur GM: Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification. Oncogene. 1990, 5 (12): 1821-1827.
CAS
PubMed
Google Scholar
Villani G, Attardi G: In vivo control of respiration by cytochrome c oxidase in wild-type and mitochondrial DNA mutation-carrying human cells. Proc Natl Acad Sci USA. 1997, 94 (4): 1166-1171. 10.1073/pnas.94.4.1166.
Article
CAS
PubMed
PubMed Central
Google Scholar
Munday AD, Sriratana A, Hill JS, Kahl SB, Nagley P: Mitochondria are the functional intracellular target for a photosensitizing boronated porphyrin. Biochimica et Biophysica Acta. 1996, 1311 (1): 1-4.
Article
PubMed
Google Scholar
Salvioli S, Maseroli R, Pazienza TL, Bobyleva V, Cossarizza A: Use of flow cytometry as a tool to study mitochondrial membrane potential in isolated, living hepatocytes. Biochemistry (Mosc). 1998, 63 (2): 235-238.
CAS
Google Scholar
Gutmann I, Wahlefeld AW: L-(+)-Lactate determination with lactate dehydrogenase and NAD. Methods of enzymatic analysis. Edited by: Bergmeyer HU. 1974, New York: Academic Press Inc, 3: 1464-1468.
Google Scholar
Single B, Leist M, Nicotera P: Differential effects of bcl-2 on cell death triggered under ATP-depleting conditions. Experimental Cell Research. 2001, 262 (1): 8-16. 10.1006/excr.2000.5059.
Article
CAS
PubMed
Google Scholar
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P: Molecular Biology of the Cell. 2002, New York, NY: Garland Science, Fourth
Google Scholar
Cuezva JM, Krajewska M, de Heredia ML, Krajewski S, Santamaria G, Kim H, Zapata JM, Marusawa H, Chamorro M, Reed JC: The bioenergetic signature of cancer: a marker of tumor progression. Cancer Res. 2002, 62 (22): 6674-6681.
CAS
PubMed
Google Scholar
Simonnet H, Alazard N, Pfeiffer K, Gallou C, Beroud C, Demont J, Bouvier R, Schagger H, Godinot C: Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma. Carcinogenesis. 2002, 23 (5): 759-768. 10.1093/carcin/23.5.759.
Article
CAS
PubMed
Google Scholar
Wu M, Neilson A, Swift AL, Moran R, Tamagnine J, Parslow D, Armistead S, Lemire K, Orrell J, Teich J, et al: Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. Am J Physiol Cell Physiol. 2007, 292 (1): C125-136. 10.1152/ajpcell.00247.2006.
Article
CAS
PubMed
Google Scholar
Salvioli S, Storci G, Pinti M, Quaglino D, Moretti L, Merlo-Pich M, Lenaz G, Filosa S, Fico A, Bonafe M, et al: Apoptosis-resistant phenotype in HL-60-derived cells HCW-2 is related to changes in expression of stress-induced proteins that impact on redox status and mitochondrial metabolism. Cell Death Differ. 2003, 10 (2): 163-174. 10.1038/sj.cdd.4401124.
Article
CAS
PubMed
Google Scholar
Ahuja V, Coleman RE, Herndon J, Patz EF: The prognostic significance of fluorodeoxyglucose positron emission tomography imaging for patients with nonsmall cell lung carcinoma. Cancer. 1998, 83 (5): 918-924. 10.1002/(SICI)1097-0142(19980901)83:5<918::AID-CNCR17>3.0.CO;2-Y.
Article
CAS
PubMed
Google Scholar
Buchmann I, Reinhardt M, Elsner K, Bunjes D, Altehoefer C, Finke J, Moser E, Glatting G, Kotzerke J, Guhlmann CA, et al: 2-(fluorine-18)fluoro-2-deoxy-D-glucose positron emission tomography in the detection and staging of malignant lymphoma. A bicenter trial. Cancer. 2001, 91 (5): 889-899. 10.1002/1097-0142(20010301)91:5<889::AID-CNCR1078>3.0.CO;2-5.
Article
CAS
PubMed
Google Scholar
Alavi JB, Alavi A, Chawluk J, Kushner M, Powe J, Hickey W, Reivich M: Positron emission tomography in patients with glioma. A predictor of prognosis. Cancer. 1988, 62 (6): 1074-1078. 10.1002/1097-0142(19880915)62:6<1074::AID-CNCR2820620609>3.0.CO;2-H.
Article
CAS
PubMed
Google Scholar
Kato H, Kuwano H, Nakajima M, Miyazaki T, Yoshikawa M, Ojima H, Tsukada K, Oriuchi N, Inoue T, Endo K: Comparison between positron emission tomography and computed tomography in the use of the assessment of esophageal carcinoma. Cancer. 2002, 94 (4): 921-928. 10.1002/cncr.10330.
Article
PubMed
Google Scholar
Meitar D, Crawford SE, Rademaker AW, Cohn SL: Tumor angiogenesis correlates with metastatic disease, N-myc amplification, and poor outcome in human neuroblastoma. J Clin Oncol. 1996, 14 (2): 405-414.
CAS
PubMed
Google Scholar
Gillies RJ, Gatenby RA: Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis?. J Bioenerg Biomembr. 2007
Google Scholar
Schornack PA, Gillies RJ: Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors. Neoplasia. 2003, 5 (2): 135-145.
Article
CAS
PubMed
PubMed Central
Google Scholar
Szatrowski TP, Nathan CF: Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 1991, 51 (3): 794-798.
CAS
PubMed
Google Scholar
Ramanathan A, Wang C, Schreiber SL: Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci USA. 2005, 102 (17): 5992-5997. 10.1073/pnas.0502267102.
Article
CAS
PubMed
PubMed Central
Google Scholar
Elstrom RL, Bauer DE, Buzzai M, Karnauskas R, Harris MH, Plas DR, Zhuang H, Cinalli RM, Alavi A, Rudin CM, et al: Akt stimulates aerobic glycolysis in cancer cells. Cancer Res. 2004, 64 (11): 3892-3899. 10.1158/0008-5472.CAN-03-2904.
Article
CAS
PubMed
Google Scholar
Krieger-Hinck N, Gustke H, Valentiner U, Mikecz P, Buchert R, Mester J, Schumacher U: Visualisation of neuroblastoma growth in a Scid mouse model using [18F]FDG and [18F]FLT-PET. Anticancer Res. 2006, 26 (5A): 3467-3472.
PubMed
Google Scholar