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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 74 of 79

  1. Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) and T cell/histiocyte-rich large B-cell lymphoma (THRLBCL) have overlapping histological features that make their diagnosis challenging. Insulin-like gro...

    Authors: Farid Kosari, Trifeh Bakhshi, Fereshteh Ameli and Maral Mokhtari
    Citation: BMC Cancer 2022 22:1359
    Content type: Research Published on:

  3. Overexpression of Fra-1 in fibroblasts causes anchorage-independent cell growth and oncogenic transformation. A high level of Fra-1 expression is found in various tumors and tumorigenic cell lines, suggesting ...

    Authors: Yuhua Song, Santai Song, Dong Zhang, Yan Zhang, Liyong Chen, Lu Qian, Ming Shi, Huibin Zhao, Zefei Jiang and Ning Guo
    Citation: BMC Cancer 2006 6:298
    Content type: Research article Published on:

  4. Cholangiocarcinoma (CC) is a malignant neoplasm of the bile ducts or the gallbladder. Targeting of growth factor receptors showed therapeutic potential in palliative settings for many solid tumors. The aim of ...

    Authors: Ling Xu, Martin Hausmann, Wolfgang Dietmaier, Silvia Kellermeier, Theresa Pesch, Manuela Stieber-Gunckel, Elisabeth Lippert, Frank Klebl and Gerhard Rogler
    Citation: BMC Cancer 2010 10:302
    Content type: Research article Published on:

  5. Synchronous primary cancers in gallbladder and liver are rarely reported. Here we report an unusual case of synchronous cancers of gallbladder carcinoma and combined hepatocellular cholangiocarcinoma.

    Authors: Zhan-Guo Zhang, Yan Chen, Ran Ji, Ya-Jie Zhao, Jian Wang, Lily Robinson, Xiao-Ping Chen and Lei Zhang
    Citation: BMC Cancer 2018 18:1046
    Content type: Case report Published on:

  6. Tyrosine-kinase inhibitor (TKI) targeting angiogenesis improves the prognosis of patients with metastatic renal cell carcinoma (RCC), but its effect is temporary. In order to understand the mechanism by which ...

    Authors: Noboru Nakaigawa, Keiichi Kondo, Daiki Ueno, Kazuhiro Namura, Kazuhide Makiyama, Kazuki Kobayashi, Koichi Shioi, Ichiro Ikeda, Takeshi Kishida, Tomohiro Kaneta, Ryogo Minamimoto, Ukihide Tateishi, Tomio Inoue and Masahiro Yao
    Citation: BMC Cancer 2017 17:39
    Content type: Research article Published on:

  7. Cortidis rhizoma (Huanglian) and its major therapeutic component, berberine, have drawn extensive attention in recent years for their anti-cancer properties. Growth inhibitory effects of berberine on multiple ty...

    Authors: Chi Man Tsang, Yuk Chun Cheung, Vivian Wai-Yan Lui, Yim Ling Yip, Guitao Zhang, Victor Weitao Lin, Kenneth Chat-Pan Cheung, Yibin Feng and Sai Wah Tsao
    Citation: BMC Cancer 2013 13:619
    Content type: Research article Published on:

  8. Esophageal cancer is the sixth leading cause of cancer death worldwide; current early detection screening tests are inadequate. Esophageal balloon cytology successfully retrieves exfoliated and scraped superfi...

    Authors: Shih-Wen Lin, Christian C Abnet, Neal D Freedman, Gwen Murphy, Rosana Risques, Donna Prunkard, Peter Rabinovitch, Qin-Jing Pan, Mark J Roth, Guo-Qing Wang, Wen-Qiang Wei, Ning Lu, Philip R Taylor, You-Lin Qiao and Sanford M Dawsey
    Citation: BMC Cancer 2013 13:578
    Content type: Research article Published on:

  9. Although chondrosarcoma is the second most common primary malignant bone tumor, treatment options are limited due to its extensive resistance to a chemo- and radiation therapy. Since shikonin has shown potent ...

    Authors: Birgit Lohberger, Dietmar Glänzer, Heike Kaltenegger, Nicole Eck, Andreas Leithner, Rudolf Bauer, Nadine Kretschmer and Bibiane Steinecker-Frohnwieser
    Citation: BMC Cancer 2022 22:758
    Content type: Research Published on:

  10. Overexpression of HER2 is observed in 20 to 30% of breast carcinomas. The use of trastuzumab has improved the treatment of these patients, especially when it is associated with docetaxel. To optimize the use o...

    Authors: Esther Schmitt, Frédérique Végran, Sandy Chevrier, Laura Burillier, Muriel Cadouot, Sarab Lizard-Nacol, Bruno Coudert, Pierre Fumoleau, Laurent Arnould and Romain Boidot
    Citation: BMC Cancer 2015 15:169
    Content type: Research article Published on:

  11. Neoadjuvant chemoradiation therapy (nCRT) is the standard treatment modality in locally advanced rectal cancer (LARC). Since response to radiotherapy (RT) is dose dependent in rectal cancer, dose escalation ma...

    Authors: Giuditta Chiloiro, Davide Cusumano, Luca Boldrini, Angela Romano, Lorenzo Placidi, Matteo Nardini, Elisa Meldolesi, Brunella Barbaro, Claudio Coco, Antonio Crucitti, Roberto Persiani, Lucio Petruzziello, Riccardo Ricci, Lisa Salvatore, Luigi Sofo, Sergio Alfieri…
    Citation: BMC Cancer 2022 22:67
    Content type: Study protocol Published on:

  12. Cancer stem cells (CSC) are believed to play a crucial role in cancer recurrence due to their resistance to conventional chemotherapy and capacity for self-renewal. Recent studies have reported that salinomyci...

    Authors: Selena Z Kuo, Katherine J Blair, Elham Rahimy, Alan Kiang, Eric Abhold, Jian-Bing Fan, Jessica Wang-Rodriguez, Xabier Altuna and Weg M Ongkeko
    Citation: BMC Cancer 2012 12:556
    Content type: Research article Published on:

  13. CST6 promoter is highly methylated in cancer, and its detection can provide important prognostic information in breast cancer patients. The aim of our study was to develop a Methylation-Sensitive High Resolution...

    Authors: Lampros Dimitrakopoulos, Panagiotis A Vorkas, Vasilis Georgoulias and Evi S Lianidou
    Citation: BMC Cancer 2012 12:486
    Content type: Research article Published on:

  14. To improve antitumor effects against metastatic renal cell carcinoma (mRCC), use of molecular target-based drugs in sequential or combination therapy has been advocated. In combination therapy, interferon (IFN...

    Authors: Masatoshi Eto, Yoshiaki Kawano, Yoshihiko Hirao, Koji Mita, Yoichi Arai, Taiji Tsukamoto, Katsuyoshi Hashine, Akio Matsubara, Tomoaki Fujioka, Go Kimura, Nobuo Shinohara, Katsunori Tatsugami, Shiro Hinotsu and Seiji Naito
    Citation: BMC Cancer 2015 15:667
    Content type: Research article Published on:

  15. Acute lymphoblastic leukemia (ALL), the most common childhood malignancy, is characterized by recurring structural chromosomal alterations and genetic alterations, whose detection is critical in diagnosis, ris...

    Authors: Honghong Zhang, Hongsheng Wang, Xiaowen Qian, Shuai Gao, Jieqi Xia, Junwen Liu, Yanqin Cheng, Jie Man and Xiaowen Zhai
    Citation: BMC Cancer 2020 20:211
    Content type: Research article Published on:

  16. 5-Fluorouracil (5FU) is a primary chemotherapeutic agent used to treat oral squamous cell carcinoma (OSCC). However, the development of drug resistance has significantly limited its clinical application. There...

    Authors: Xuyang Zhang, Kairui Sun, Ruihuan Gan, Yuxiang Yan, Chaochao Zhang, Dali Zheng and Youguang Lu
    Citation: BMC Cancer 2024 24:564
    Content type: Research Published on:

  17. We retrospectively reviewed outcomes of treatment with pazopanib, an oral multi-tyrosine kinase angiogenesis inhibitor, in patients with advanced soft tissue sarcoma, a rare and heterogeneous tumor group with ...

    Authors: Kwai Han Yoo, Hyo Song Kim, Su Jin Lee, Se Hoon Park, Sung Joo Kim, Soo Hee Kim, Yoon La Choi, Kyoo-Ho Shin, Yong Jin Cho, Jeeyun Lee and Sun Young Rha
    Citation: BMC Cancer 2015 15:154
    Content type: Research article Published on:

  18. Bladder leiomyosarcoma is the most frequent mesenchymal neoplasm of the bladder. However, the rarity of the disease and some morphological aspects could give serious problems to differential diagnosis.

    Authors: Vincenzo Fiorentino, Francesco Pierconti, Niccolò Lenci, Martina Calicchia, Giuseppe Palermo, Pierfrancesco Bassi, Luigi Maria Larocca and Maurizio Martini
    Citation: BMC Cancer 2019 19:763
    Content type: Case report Published on:

  19. SMAD4 is a gastrointestinal malignancy-specific tumor suppressor gene found mutated in one third of colorectal cancer specimens and half of pancreatic tumors. SMAD4 inactivation by allelic deletion or intragen...

    Authors: Yu-Wen Chen, Pi-Jung Hsiao, Ching-Chieh Weng, Kung-Kai Kuo, Tzu-Lei Kuo, Deng-Chyang Wu, Wen-Chun Hung and Kuang-Hung Cheng
    Citation: BMC Cancer 2014 14:181
    Content type: Research article Published on:

  20. Hypoxia-inducible transcription factor-1α (HIF-1α), which plays an important role in controlling the hypoxia-induced glycolysis pathway, is a "master" gene in the tissue hypoxia response during tumor developme...

    Authors: FengMing Luo, XiaoJing Liu, NaiHong Yan, ShuangQing Li, GuiQun Cao, QingYing Cheng, QingJie Xia and HongJing Wang
    Citation: BMC Cancer 2006 6:26
    Content type: Research article Published on:

  21. Patients with small intestinal neuroendocrine tumors (SINETs) frequently present with lymph node and liver metastases at the time of diagnosis, but the molecular changes that lead to the progression of these t...

    Authors: Tobias Hofving, Erik Elias, Anna Rehammar, Linda Inge, Gülay Altiparmak, Marta Persson, Erik Kristiansson, Martin E. Johansson, Ola Nilsson and Yvonne Arvidsson
    Citation: BMC Cancer 2021 21:101
    Content type: Research article Published on:

  22. Limited studies examine the immune landscape in Esophageal Adenocarcinoma (EAC). We aim to identify novel associations, which may inform immunotherapy treatment stratification.

    Authors: Matthew P. Humphries, Stephanie G. Craig, Rafal Kacprzyk, Natalie C. Fisher, Victoria Bingham, Stephen McQuaid, Graeme I. Murray, Damian McManus, Richard C. Turkington, Jacqueline James and Manuel Salto-Tellez
    Citation: BMC Cancer 2020 20:500
    Content type: Research article Published on:

  23. In patients with metastatic renal cell cancer, based on limited evidence, increased sunitinib exposure is associated with better outcome. The survival and toxicity data of patients receiving individualized dos...

    Authors: Anikó Maráz, Adrienn Cserháti, Gabriella Uhercsák, Éva Szilágyi, Zoltán Varga, János Révész, Renáta Kószó, Linda Varga and Zsuzsanna Kahán
    Citation: BMC Cancer 2018 18:296
    Content type: Research article Published on:

  24. Hepatocellular carcinoma (HCC) has been associated with diabetes and obesity, but a possible connection with the metabolic syndrome (MetS) and its potential interaction with hepatitis and cirrhosis are open to...

    Authors: De-cai Yu, Jia Liu, Jun Chen, Jiao-jiao Shao, Xiao Shen, Hong-guang Xia, Chao-jun Li, Bin Xue and Yi-tao Ding
    Citation: BMC Cancer 2014 14:248
    Content type: Research article Published on:

  25. The cellular response of malignant tumors to hypoxia is diverse. Several important endogenous metabolic markers are upregulated under hypoxic conditions. We examined the staining patterns and co-expression of ...

    Authors: Saskia E Rademakers, Jasper Lok, Albert J van der Kogel, Johan Bussink and Johannes HAM Kaanders
    Citation: BMC Cancer 2011 11:167
    Content type: Research article Published on:

  26. Accurate identification of extrahepatic cholangiocarcinoma (ECC) from an image is challenging because of the small size and complex background structure. Therefore, considering the limitation of manual delinea...

    Authors: Chunmei Yang, Qin Zhou, Mingdong Li, Lulu Xu, Yanyan Zeng, Jiong Liu, Ying Wei, Feng Shi, Jing Chen, Pinxiong Li, Yue Shu, Lu Yang and Jian Shu
    Citation: BMC Cancer 2023 23:1089
    Content type: Research Published on:

  27. Three-dimensional (3-D) cultures of cancer cells can potentially bridge the gap between 2-D drug screening and in vivo xenografts. The objective of this study was to characterize the cellular and extracellular...

    Authors: Surya P. Lamichhane, Neha Arya, Esther Kohler, Shengnan Xiang, Jon Christensen and V. Prasad Shastri
    Citation: BMC Cancer 2016 16:581
    Content type: Research article Published on:

  28. Immune checkpoint inhibitors (ICI) treatment in recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) offers new therapeutic venues. We have previously developed a predictive survival model ...

    Authors: Majd Issa, Brett G. Klamer, Nikol Mladkova, Georgios I. Laliotis, Vidhya Karivedu, Priyanka Bhateja, Chase Byington, Khaled Dibs, Xueliang Pan, Arnab Chakravarti, John Grecula, Sachin R. Jhawar, Darrion Mitchell, Sujith Baliga, Matthew Old, Ricardo L. Carrau…
    Citation: BMC Cancer 2022 22:767
    Content type: Research Published on:

  29. With poor prognosis and limited treatment options for advanced hepatocellular carcinoma (HCC), development of novel therapeutic agents is urgently needed. This single-arm phase I study sought to assess the saf...

    Authors: Ying Fan, Shu Li, Xiaoyan Ding, Jian Yue, Jun Jiang, Hong Zhao, Rui Hao, Weiliang Qiu, Kezhen Liu, Ying Li, Shengdian Wang, Limin Zheng, Bin Ye, Kun Meng and Binghe Xu
    Citation: BMC Cancer 2019 19:279
    Content type: Research article Published on:

  30. To date, there have been no reports characterizing the genome-wide somatic DNA chromosomal copy-number alteration landscape in metastatic urothelial carcinoma. We sought to characterize the DNA copy-number pro...

    Authors: Richard M Bambury, Ami S Bhatt, Markus Riester, Chandra Sekhar Pedamallu, Fujiko Duke, Joaquim Bellmunt, Edward C Stack, Lillian Werner, Rachel Park, Gopa Iyer, Massimo Loda, Philip W Kantoff, Franziska Michor, Matthew Meyerson and Jonathan E Rosenberg
    Citation: BMC Cancer 2015 15:242
    Content type: Research article Published on:

  31. Sarcomas constitute a heterogeneous group of tumors with different clinical behaviors and variable responses to systemic therapies. Recent immunotherapy studies with PD1 inhibitors (PD1i) show promising result...

    Authors: Dionisia Quiroga, David A. Liebner, Jennifer S. Philippon, Sarah Hoffman, Yubo Tan, James L. Chen, Scott Lenobel, Paul E. Wakely Jr, Raphael Pollock and Gabriel Tinoco
    Citation: BMC Cancer 2020 20:527
    Content type: Research article Published on:

  32. High grade serous ovarian cancer is characterised by high initial response to chemotherapy but poor outcome in the long term due to acquired resistance. One of the main genetic features of this disease is TP53 mu...

    Authors: Alba Mota, Juan Carlos Triviño, Alejandro Rojo-Sebastian, Ángel Martínez-Ramírez, Luis Chiva, Antonio González-Martín, Juan F. Garcia, Pablo Garcia-Sanz and Gema Moreno-Bueno
    Citation: BMC Cancer 2015 15:940
    Content type: Research article Published on:

  33. Caveolin-1 is the main component of caveolae membrane structures and has different roles during tumorigenesis in different cancer types with varying expression profiles, indicating that the role of caveolin-1 ...

    Authors: Murat Cokakli, Esra Erdal, Deniz Nart, Funda Yilmaz, Ozgul Sagol, Murat Kilic, Sedat Karademir and Nese Atabey
    Citation: BMC Cancer 2009 9:65
    Content type: Research article Published on:

  34. PMS2 expression loss was reported in a variety of human. However, its importance has not been fully understood in cervical carcinoma. The aim of this study was to determine the expression of PMS2 in cervical c...

    Authors: Yuan Zhang, Yi Min Shu, Shu Fang Wang, Bang Hong Da, Ze Hua Wang and Hua Bin Li
    Citation: BMC Cancer 2010 10:58
    Content type: Research article Published on:

  36. Wilms’ tumor is also called nephroblastoma and is the most common pediatric renal cancer. Several genetic and epigenetic factors have been found to account for the development of Wilms’ tumor. MiRNAs play impo...

    Authors: Zhuo Liu, Feng He, Shengrong OuYang, Yuanyuan Li, Feifei Ma, Huibo Chang, Dingding Cao and Jianxin Wu
    Citation: BMC Cancer 2019 19:405
    Content type: Research article Published on:

  38. The effects of sorafenib in the treatment of advanced renal cell carcinoma (RCC) have been confirmed in an international collaborative phase III trial. This study aims to confirm similar efficacy and treatment...

    Authors: Hailiang Zhang, Baijun Dong, Jiade J Lu, Xudong Yao, Shilin Zhang, Bo Dai, Yijun Shen, Yao Zhu, Dingwei Ye and Yiran Huang
    Citation: BMC Cancer 2009 9:249
    Content type: Research article Published on:

  40. In Japan, transarterial infusion chemotherapy using cisplatin (CDDP-TAI) is frequently used for advanced hepatocellular carcinoma (HCC). Moreover, oral chemotherapy with S-1, an oral fluoropyrimidine derivativ...

    Authors: Tetsuji Terazawa, Shunsuke Kondo, Hiroko Hosoi, Chigusa Morizane, Satoshi Shimizu, Shuichi Mitsunaga, Masafumi Ikeda, Hideki Ueno and Takuji Okusaka
    Citation: BMC Cancer 2014 14:301
    Content type: Research article Published on:

  41. It has been proposed that mesenchymal stromal cells (MSCs) promote tumor progression by interacting with tumor cells and other stroma cells in the complex network of the tumor microenvironment. We characterize...

    Authors: Gloria Pelizzo, Veronica Veschi, Melissa Mantelli, Stefania Croce, Vincenzo Di Benedetto, Paolo D’Angelo, Alice Maltese, Laura Catenacci, Tiziana Apuzzo, Emanuela Scavo, Antonia Moretta, Matilde Todaro, Giorgio Stassi, Maria Antonietta Avanzini and Valeria Calcaterra
    Citation: BMC Cancer 2018 18:1176
    Content type: Research article Published on:

  42. Smoking induces oncogenic TP53-mutations in head and neck squamous cell carcinomas (HNSCCs). Disruptive mutations of TP53-gene and expression of p16 protein [p16 (+)] in tumor tissue associate with worse and bett...

    Authors: Aki Mafune, Takanori Hama, Toshihito Suda, Yutaka Suzuki, Masahiro Ikegami, Chikako Sakanashi, Satoko Imai, Akio Nakashima, Takashi Yokoo, Kota Wada, Hiromi Kojima and Mitsuyoshi Urashima
    Citation: BMC Cancer 2015 15:205
    Content type: Research article Published on:

  43. Clinical care of unstable spinal bone metastases in many centers often includes patient immobilization by means of an orthopedic corset in order to prevent pathological fractures. The aim of this retrospective...

    Authors: Harald Rief, Robert Förster, Stefan Rieken, Thomas Bruckner, Ingmar Schlampp, Tilman Bostel and Jürgen Debus
    Citation: BMC Cancer 2015 15:745
    Content type: Research article Published on:

  44. Single nucleotide polymorphisms (SNPs) located in microRNA (miRNA) binding sites can affect the interactions between miRNAs and target genes, which is related to cancer susceptibility and tumorigenesis. Howeve...

    Authors: Yi Shen, Yi Shao, Xiaoli Ruan, Lingyan Zhu, Zhaoping Zang, Tong Wei, Rena Nakyeyune, Wenqiang Wei and Fen Liu
    Citation: BMC Cancer 2022 22:1253
    Content type: Research Published on:

  45. Nuclear factor E2-related factor 2 (Nrf2 or NFE2L2) is abundantly expressed in cancer cells and relates to proliferation, invasion, and chemoresistance. Our early observations also found that expression of Nrf...

    Authors: Mingxin Zhang, Chao Zhang, Lingmin Zhang, Qi Yang, Suna Zhou, Qinsheng Wen and Jingjie Wang
    Citation: BMC Cancer 2015 15:531
    Content type: Research article Published on:

  46. The aims of this study were to evaluate the impact of initial uterus-preserving surgery, such as myomectomy or subtotal hysterectomy, on the recurrence rates of patients with uterine sarcoma found incidentally...

    Authors: Jung-Yun Lee, Hyun Soo Kim, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim and Young Tae Kim
    Citation: BMC Cancer 2016 16:675
    Content type: Research article Published on:

  47. Several studies in the past have investigated the expression of micro RNAs (miRNAs) in saliva as potential biomarkers. Since miRNAs associated with extracellular vesicles (EVs) are known to be protected from e...

    Authors: Chiara Gai, Francesco Camussi, Roberto Broccoletti, Alessio Gambino, Marco Cabras, Luca Molinaro, Stefano Carossa, Giovanni Camussi and Paolo G. Arduino
    Citation: BMC Cancer 2018 18:439
    Content type: Research article Published on:

  48. Primary tracheal tumors are very rare and their management is not definitely established. Due to its rarity, providing patient care in terms of optimal management poses a considerable challenge. The purpose of...

    Authors: Aleksandra Piórek, Adam Płużański, Magdalena Knetki-Wróblewska, Kinga Winiarczyk, Sylwia Tabor, Paweł Teterycz, Dariusz M. Kowalski and Maciej Krzakowski
    Citation: BMC Cancer 2024 24:686
    Content type: Research Published on:

  50. Glioblastoma multiforme (GBM) is the most severe type of primary brain tumor with a high mortality rate. Although extensive treatments for GBM, including resection, irradiation, chemotherapy and immunotherapy,...

    Authors: Jui-Chieh Chen, I-Neng Lee, Cheng Huang, Yu-Ping Wu, Chiu-Yen Chung, Ming-Hsueh Lee, Martin Hsiu-Chu Lin and Jen-Tsung Yang
    Citation: BMC Cancer 2019 19:756
    Content type: Research article Published on:

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