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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. Tregs are able of suppressing tumor-specific effector cells, such as lymphocytes CD8+, CD4+ and Natural Killer cells. Different drugs, especially different schedules of administration, like metronomic chemothe...

    Authors: F. F. Pepe, M. E. Cazzaniga, S. Baroni, F. Riva, F. Cicchiello, S. Capici, V. Cogliati, C. Maggioni, N. Cordani, M. G. Cerrito and S. Malandrin
    Citation: BMC Cancer 2022 22:956
    Content type: Research Published on:

  2. Pancreatic peritoneal carcinomatosis (PPC), with the worst median overall-survival (mOS), epitomizes the incurability of metastatic cancer. Cancer stem cells (CSCs) underpin this incurability. However, inhibit...

    Authors: Christopher M. Gromisch, Glaiza L. A. Tan, Khristine Amber Pasion, Ann-Marie Moran, Matthew S. Gromisch, Mark W. Grinstaff, Francis J. Carr, Victoria L. M. Herrera and Nelson Ruiz-Opazo
    Citation: BMC Cancer 2021 21:407
    Content type: Research article Published on:

  3. The purpose of this study was to evaluate the prognostic implication of findings of intratumoral metabolic heterogeneity on pretreatment 18F-FDG PET/CT scans in patients with invasive ductal carcinoma (IDC) of th...

    Authors: Seung Hyun Son, Do-Hoon Kim, Chae Moon Hong, Choon-Young Kim, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee and Byeong-Cheol Ahn
    Citation: BMC Cancer 2014 14:585
    Content type: Research article Published on:

  4. Prostate cancer is a common solid tumor that affects a significant number of men worldwide. Conventional androgen deprivation therapy (ADT) increases the risk of developing castration-resistant prostate cancer...

    Authors: Xingchen Dai, Xinyi Shi, Mingxiu Luo, Pu Li and Yujing Gao
    Citation: BMC Cancer 2023 23:1241
    Content type: Research Published on:

  5. The chemotherapy triplet FOLFOXIRI combined to the anti-VEGF antibody bevacizumab is an option in selected patients with metastatic colorectal cancer. In this setting, RAS-mutated metastatic colorectal cancer ...

    Authors: Antoine Adenis, Thibault Mazard, Julien Fraisse, Patrick Chalbos, Brice Pastor, Ludovic Evesque, Francois Ghiringhelli, Caroline Mollevi, Stéphanie Delaine and Marc Ychou
    Citation: BMC Cancer 2021 21:564
    Content type: Study protocol Published on:

  6. Evidences have indicated that miR-26a-5p regulates the malignant properties of various tumor cells. However, the influences of miR-26a-5p on proliferation, apoptosis and invasion are still vague in the cervica...

    Authors: Ming Li, Yubo Xiao, Minqi Liu, Qian Ning, Ziye Xiang, Xiang Zheng, Shengsong Tang and Zhongcheng Mo
    Citation: BMC Cancer 2022 22:876
    Content type: Research Published on:

  8. Polo-like kinase 1 (Plk1) is a serine/threonine kinase that is a key regulator of multiple stages of mitotic progression. Plk1 is upregulated in many tumor types including colorectal cancer (CRC) and portends ...

    Authors: Peter J. Klauck, Stacey M. Bagby, Anna Capasso, Erica L. Bradshaw-Pierce, Heather M. Selby, Anna Spreafico, John J. Tentler, Aik Choon Tan, Jihye Kim, John J. Arcaroli, Alicia Purkey, Wells A. Messersmith, Keisuke Kuida, S. Gail Eckhardt and Todd M. Pitts
    Citation: BMC Cancer 2018 18:136
    Content type: Research article Published on:

  9. Conventionally fractionated (CF) radiation therapy (RT) has been associated with lymphopenia, leading to compromised overall survival (OS) in cancer patients. It currently remains unknown if stereotactic body ...

    Authors: Guangyin Wu, Michael J. Baine, Nan Zhao, Sicong Li, Xiaobo Li and Chi Lin
    Citation: BMC Cancer 2019 19:977
    Content type: Research article Published on:

  10. To assess the diagnostic performance of a panel of standard tumor markers (TMs) in patients hospitalized with significant involuntary weight loss (IWL) and elevated levels of inflammation biomarkers, and a com...

    Authors: Morgane Gronnier, Kaies Hedhli, Chloé Sauzay, Valéry Salle, Pierre Duhaut, Jean Schmidt and Amandine Dernoncourt
    Citation: BMC Cancer 2024 24:468
    Content type: Research Published on:

  11. In Mainland China, advance directives (ADs) and end-of-life care for patients with tumours, especially patients with brain tumours who may have lost consciousness or the ability to speak at the early stage of ...

    Authors: Yixin Wang, Yongkang Zhang, Yang Hong, Ping Zeng, Zongtao Hu, Xiuli Xu and Hongzhi Wang
    Citation: BMC Cancer 2021 21:25
    Content type: Research article Published on:

  12. For patients with metastatic renal cell carcinoma (mRCC), targeted therapies have entered the market since 2006. The aims of this study were to evaluate the uptake and use of targeted therapies for mRCC in The...

    Authors: S. De Groot, S. Sleijfer, W. K. Redekop, E. Oosterwijk, J. B. A. G. Haanen, L. A. L. M. Kiemeney and C. A. Uyl-de Groot
    Citation: BMC Cancer 2016 16:364
    Content type: Research article Published on:

  13. Tumor microenvironment (TME) is a dynamic setting and changes in TILs and their subpopulations are potential candidates to influence the metastatic process. Aim of this pilot study is to describe the changes o...

    Authors: Annalisa Zeppellini, Stefania Galimberti, Biagio Eugenio Leone, Claudia Pacifico, Francesca Riva, Federica Cicchiello, Serena Capici, Claudia Maggioni, Luca Sala and Marina Elena Cazzaniga
    Citation: BMC Cancer 2021 21:260
    Content type: Research article Published on:

  14. Although perineural invasion (PNI) is well-known to be correlated with and able to predict lymph node metastasis (LNM) in oral squamous cell carcinoma (OSCC), the clinical and molecular correlation between PNI...

    Authors: Yu Zhang, Mingtao Chen, Zheqi Liu, Xu Wang and Tong Ji
    Citation: BMC Cancer 2021 21:1254
    Content type: Research Published on:

  15. Increasing evidence shows that dysregulated long non-coding RNAs (lncRNAs) can serve as potential biomarkers for cancer prognosis. However, lncRNA signatures, as potential prognostic biomarkers for esophageal ...

    Authors: Guo-Wei Huang, Yu-Jie Xue, Zhi-Yong Wu, Xiu-E Xu, Jian-Yi Wu, Hui-Hui Cao, Ying Zhu, Jian-Zhong He, Chun-Quan Li, En-Min Li and Li-Yan Xu
    Citation: BMC Cancer 2018 18:147
    Content type: Research article Published on:

  16. VEGF/VEGFR2 pathway is the central therapeutic target in anti-angiogenic treatment in multiple cancers. However, little work has been carried out concerning the pro-malignancy functions of VEGFR2 that are inde...

    Authors: Lian Lian, Xiang-Li Li, Meng-Dan Xu, Xian-Min Li, Meng-Yao Wu, Yan Zhang, Min Tao, Wei Li, Xiao-Ming Shen, Chong Zhou and Min Jiang
    Citation: BMC Cancer 2019 19:183
    Content type: Research article Published on:

  17. There is no comprehensive agreement concerning the overall performance of radical resection for T1b gallbladder cancer (GBC). This research focused on addressing whether T1b GBC may spread loco-regionally and ...

    Authors: Kizuki Yuza, Jun Sakata, Pankaj Prasoon, Yuki Hirose, Taku Ohashi, Koji Toge, Kohei Miura, Masayuki Nagahashi, Takashi Kobayashi and Toshifumi Wakai
    Citation: BMC Cancer 2020 20:20
    Content type: Research article Published on:

  18. Esophageal and gastric cancers are a significant public health problem worldwide, with most patients presenting with advanced-stage disease and, consequently, poor prognosis. Systemic oncological treatments (S...

    Authors: M. Santero, J. Pérez-Bracchiglione, R. Acosta-Dighero, A. G. Meade, A. Antequera, A. Auladell-Rispau, M. J. Quintana, C. Requeijo, G. Rodríguez-Grijalva, K. Salas-Gama, R. Dorantes-Romandia, J. Salazar, I. Solà, G. Urrútia and X. Bonfill Cosp
    Citation: BMC Cancer 2021 21:712
    Content type: Research Published on:

  19. Elevated red blood cell distribution width (RDW) and decreased platelet count (PLT) can be clinically relevant to the prognosis in cancer patients. However, their prognostic values in patients with diffuse lar...

    Authors: Manman Li, Hailong Xia, Huimin Zheng, Yafeng Li, Jun Liu, Linhui Hu, Jingrong Li, Yangyang Ding, Lianfang Pu, Qianle Gui, Yijie Zheng, Zhimin Zhai and Shudao Xiong
    Citation: BMC Cancer 2019 19:1084
    Content type: Research article Published on:

  20. Reg IV is a member of the regenerating gene family and has been demonstrated to be overexpressed in gastric cancer. However, the functional mechanism of Reg IV in gastric cancer is still unclear.

    Authors: Na Zhang, Dandan Chai, Huifen Du, Kesheng Li, Wenguang Xie, Xingwen Li, Rong Yang, Xiaowen Lian and Yang Xu
    Citation: BMC Cancer 2018 18:344
    Content type: Research article Published on:

  21. Patterns of failure after treatment of oral and squamous cell carcinomas (OSCC) are diversified, with recurrences being one of the common causes. A special group of patients are sometimes encountered in the ou...

    Authors: Yue He, Zhonglong Liu, Surui Sheng, Weijin Gao, Xiao Tang, Xiaoguang Li and Chunyue Ma
    Citation: BMC Cancer 2021 21:878
    Content type: Research article Published on:

  22. We aimed to identify effective routinely collected laboratory biomarkers for predicting postoperative outcomes in surgically treated spinal metastases and attempted to establish an effective prediction model.

    Authors: Zhehuang Li, Lingling Huang, Bairu Guo, Peng Zhang, Jiaqiang Wang, Xin Wang and Weitao Yao
    Citation: BMC Cancer 2022 22:1231
    Content type: Research Published on:

  23. The vast majority of ovarian mucinous carcinomas are metastatic tumours derived from nonovarian primary cancers, typically gastrointestinal neoplasms. Therapy targeting claudin18.2 might be used in gastric, ga...

    Authors: Fujun Wang, Yao Yang, Xiuzhen Du, Xiaoying Zhu, Yanjiao Hu, Changyu Lu, Lei Sui, Han Zhao, Kejuan Song and Qin Yao
    Citation: BMC Cancer 2023 23:44
    Content type: Research Published on:

  25. Adult head and neck rhabdomyosarcoma (HNRMS) is an exceptionally rare malignancy, and there is a paucity of data and research dedicated to understanding its characteristics and management in adult populations....

    Authors: Dan Zhao, Fang Zhou, Weixin Liu, Zhou Huang, Xiaolong Xu, Baomin Zheng, Changqing Liu, Chujie Bai, Jiayong Liu, Yan Sun, Weihu Wang and Shaowen Xiao
    Citation: BMC Cancer 2024 24:340
    Content type: Research Published on:

  26. Gastric cancer (GC) is one of the most common malignant diseases with high morbidity and mortality, especially in Asian countries. During the GC developing progress, TIPE2, a member of TNF-alpha induced protei...

    Authors: Wenming Liu, Yanyun Fan, Ying Shi, Zhenhe Lin, Xiaoxiao Huang, Wei Huang, Dongyan Shen and Zhongquan Qi
    Citation: BMC Cancer 2018 18:857
    Content type: Research article Published on:

  27. We reported increased levels of Phosphatidyl Inositol synthase (PI synthase), (enzyme that catalyses phosphatidyl inositol (PI) synthesis-implicated in intracellular signaling and regulation of cell growth) in...

    Authors: Jatinder Kaur, Meenakshi Sawhney, Siddartha DattaGupta, Nootan K Shukla, Anurag Srivastava and Ranju Ralhan
    Citation: BMC Cancer 2010 10:168
    Content type: Research article Published on:

  28. Skin cancer is the most common cancer worldwide and commonly classified into malignant melanoma (MM) and Nonmelanoma skin cancers (NMSCs), which mainly include basal cell carcinoma (BCC) and squamous cell carc...

    Authors: Mohammad Ali Zolfaghari, Abbas Karimi, Elham Kalantari, Alireza Korourian, Alireza Ghanadan, Kambiz Kamyab, Nafiseh Esmaili, Amir Nader Emami Razavi and Zahra Madjd
    Citation: BMC Cancer 2020 20:567
    Content type: Research article Published on:

  29. Breast cancer (BC) is the most frequent female cancer and preferentially metastasizes to bone. The transcription factor TGFB-induced factor homeobox 1 (TGIF) is involved in bone metabolism. However, it is not ...

    Authors: Christine Stürken, Volker Möbus, Karin Milde-Langosch, Sabine Schmatloch, Peter A. Fasching, Josef Rüschoff, Elmar Stickeler, Rolf-Peter Henke, Carsten Denkert, Lars Hanker, Christian Schem, Valentina Vladimirova, Thomas Karn, Valentina Nekljudova, Claus-Henning Köhne, Frederik Marmé…
    Citation: BMC Cancer 2021 21:920
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2021 21:1024

  30. We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors’ aggre...

    Authors: Mina Waraya, Keishi Yamashita, Hiroshi Katoh, Akira Ooki, Hiroshi Kawamata, Hiroshi Nishimiya, Kazunori Nakamura, Akira Ema and Masahiko Watanabe
    Citation: BMC Cancer 2012 12:397
    Content type: Research article Published on:

  31. Merkel cell carcinoma (MCC) is a rare cutaneous neoplasm with increasing incidence, aggressive behavior and poor prognosis. Somatostatin receptors (SSTR) are expressed in MCC and represent a potential target f...

    Authors: Kristina Buder, Constantin Lapa, Michael C Kreissl, Andreas Schirbel, Ken Herrmann, Alexander Schnack, Eva-Bettina Bröcker, Matthias Goebeler, Andreas K Buck and Jürgen C Becker
    Citation: BMC Cancer 2014 14:268
    Content type: Research article Published on:

  32. We aimed to investigate the correlation of Circ-SMARCA5 with disease severity and prognosis in multiple myeloma (MM), and its underlying mechanisms in regulating cell proliferation and apoptosis.

    Authors: Haiyan Liu, Yan Wu, Shunye Wang, Jie Jiang, Chenlu Zhang, Yijing Jiang, Xingfeng Wang, Lewen Hong and Hongming Huang
    Citation: BMC Cancer 2019 19:937
    Content type: Research article Published on:

  33. Long non coding RNAs (lncRNAs) are RNA molecules longer than 200 nucleotides that are not translated into proteins, but regulate the transcription of genes involved in different cellular processes, including c...

    Authors: Maria Barton, Julia Santucci-Pereira, Olivia G. Vaccaro, Theresa Nguyen, Yanrong Su and Jose Russo
    Citation: BMC Cancer 2019 19:994
    Content type: Research article Published on:

  34. This study aimed to propose a new user-friendly, cost effective and robust risk model to facilitate risk stratification for diffuse large B-cell lymphoma (DLBCL) treated with frontline R-CHOP regimens.

    Authors: Haizhu Chen, Qiaofeng Zhong, Yu Zhou, Yan Qin, Jianliang Yang, Peng Liu, Xiaohui He, Shengyu Zhou, Changgong Zhang, Lin Gui, Sheng Yang, Liqiang Zhou and Yuankai Shi
    Citation: BMC Cancer 2022 22:583
    Content type: Research Published on:

  35. The interruption of normal cell cycle execution acts as an important part to the development of leukemia. It was reported that microRNAs (miRNAs) were closely related to tumorigenesis and progression, and thei...

    Authors: Bei Xie, Lei Zhao, Zhewen Zhang, Cunmin Zhou, Ye Tian, Yingying Kang, Jing Chen, Hulai Wei and Linjing Li
    Citation: BMC Cancer 2023 23:955
    Content type: Research Published on:

  36. Eukaryotic translation initiation factors (eIFs) are the key factors to synthesize translation initiation complexes during the synthesis of eukaryotic proteins. Besides, eIFs are especially important in regula...

    Authors: Qi Li, Mulun Xiao, Yibo Shi, Jinhao Hu, Tianxiang Bi, Chaoliang Wang, Liang Yan and Xiaoyan Li
    Citation: BMC Cancer 2021 21:1022
    Content type: Research Published on:

  38. Although bone marrow metastases can be found commonly in some malignant tumors, diagnosing a nonhematologic malignancy from marrow is not a usual event.

    Authors: Fahir Ozkalemkas, Rıdvan Ali, Vildan Ozkocaman, Tulay Ozcelik, Ulku Ozan, Hulya Ozturk, Ender Kurt, Turkkan Evrensel, Omer Yerci and Ahmet Tunali
    Citation: BMC Cancer 2005 5:144
    Content type: Research article Published on:

  39. A number of studies have investigated the association between androgenic alopecia (AGA) and cancer risk, but they have yielded inconsistent results. Therefore, this study was conducted to explore this controve...

    Authors: Weijun Liang, Liuying Song, Zheng Peng, Yan Zou and Shengming Dai
    Citation: BMC Cancer 2018 18:279
    Content type: Research article Published on:

  40. The purpose of this study was to construct a new typing model for diffuse large B-cell lymphoma (DLBCL) patients based on the B-cell receptor (BCR) and explore its potential molecular mechanism.

    Authors: Wenhua Jiang, Hailong Wang, Shiyong Zhou, Guoqing Zhu, Mingyou Gao, Kuo Zhao, Limeng Zhang, Xiaojing Xie, Ning Zhao, Caijuan Tian, Zhenzhen Zhang, Fang Yan, Yi Pan and Pengfei Liu
    Citation: BMC Cancer 2021 21:297
    Content type: Research article Published on:

  41. The establishment of sister chromatid cohesion N-acetyltransferase 2 (ESCO2) is involved in the development of multiple malignancies. However, its role in hypopharyngeal carcinoma (HPC) progression remains unc...

    Authors: Juan Hu, Jing Yan, Yijie Chen, Xiaohui Li, Liu Yang, Haiyu Di, Huihui Zhang, Yewen Shi, Junjie Zhao, Yanxia Shi, Yinglong Xu, Xiaoyong Ren and Zhenghui Wang
    Citation: BMC Cancer 2023 23:1114
    Content type: Research Published on:

  42. Despite advancements in managing metastatic clear cell renal carcinoma (mccRCC) through antiangiogenic tyrosine kinase inhibitors and immunotherapy, there remains a demand for novel treatments for patients exp...

    Authors: David Kryza, Armelle Vinceneux, Anne-Sophie Bidaux, Gwenaelle Garin, Delphine Tatu, Claire Cropet, Jean-Noël Badel, David Perol and Anne-Laure Giraudet
    Citation: BMC Cancer 2024 24:163
    Content type: Study Protocol Published on:

  43. Chemoresistance is one of the main problems in treatment of cancer. Periostin (PN) is a stromal protein which is mostly secreted from cancer associated fibroblasts in the tumor microenvironment and can promote...

    Authors: Khine Kyaw Oo, Thanpawee Kamolhan, Anish Soni, Suyanee Thongchot, Chalermchai Mitrpant, Pornchai O-charoenrat, Chanitra Thuwajit and Peti Thuwajit
    Citation: BMC Cancer 2021 21:65
    Content type: Research article Published on:

  44. Gastric cancer remains the second leading cause of cancer-related deaths in the world. Successful early gastric cancer detection is hampered by lack of highly sensitive and specific biomarkers. Plasma membrane...

    Authors: Wen Gao, Jing Xu, Fuqiang Wang, Long Zhang, Rui Peng, Yongqian Shu, Jindao Wu, Qiyun Tang and Yunxia Zhu
    Citation: BMC Cancer 2015 15:367
    Content type: Research article Published on:

  45. Menacalc is an immunofluorescence-based, quantitative method in which expression of the non-invasive Mena protein isoform (Mena11a) is subtracted from total Mena protein expression. Previous work has found a sign...

    Authors: Catherine L. Forse, Seema Agarwal, Dushanthi Pinnaduwage, Frank Gertler, John S. Condeelis, Juan Lin, Xiaonan Xue, Kimberly Johung, Anna Marie Mulligan, Thomas E. Rohan, Shelley B. Bull and Irene L. Andrulis
    Citation: BMC Cancer 2015 15:483
    Content type: Research article Published on:

  46. Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer (BC). The circRNA-miRNA‒mRNA axis is a promising biomarker for the early diagnosis and prognosis of BC. However, the critical ci...

    Authors: Jie Ren, Wei Chen, Ya Zhou, Jianxiong Sun and Guoqin Jiang
    Citation: BMC Cancer 2024 24:278
    Content type: Research Published on:

  47. Primary liver cancer is a malignant tumour of the digestive system, ranking second in cancer mortality in China. In different types of cancer, such as liver cancer, microRNAs (miRNAs) have been shown to be dys...

    Authors: Jing Yan, Bei Xie, Ye Tian, Wenqin An, Zhiheng Peng, Zhuan Liu, Jing Li and Linjing Li
    Citation: BMC Cancer 2023 23:557
    Content type: Research Published on:

  48. This study aimed to evaluate the efficiency and prognostic factors of lenvatinib plus programmed death 1 (PD-1) blockades in patients with advanced hepatocellular carcinoma (HCC), especially for those with tum...

    Authors: Xuqi Sun, Qi Zhang, Jie Mei, Ziliang Yang, Minshan Chen and Tingbo Liang
    Citation: BMC Cancer 2022 22:293
    Content type: Research Published on:

  49. Gastric cancer is the third most common malignancy affecting the general population worldwide. Aberrant activation of KRAS is a key factor in the development of many types of tumor, however, oncogenic mutation...

    Authors: Hiroaki Mita, Minoru Toyota, Fumio Aoki, Hirofumi Akashi, Reo Maruyama, Yasushi Sasaki, Hiromu Suzuki, Masashi Idogawa, Lisa Kashima, Kazuyoshi Yanagihara, Masahiro Fujita, Masao Hosokawa, Masanobu Kusano, Sorin Vasile Sabau, Haruyuki Tatsumi, Kohzoh Imai…
    Citation: BMC Cancer 2009 9:198
    Content type: Research article Published on:

  50. Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. The disease recurrent rate is relatively high resulted in poor 5-year survival in advanced HCC. Cancer stem cells (...

    Authors: Wei-Chieh Huang, Shiao-Lin Tung, Yao-Li Chen, Po-Ming Chen and Pei-Yi Chu
    Citation: BMC Cancer 2018 18:609
    Content type: Research article Published on:

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