Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–49.
PubMed
Google Scholar
Xia C, Dong X, Li H, Cao M, Sun D, He S, et al. Cancer statistics in China and United States, 2022: profiles, trends, and determinants. Chin Med J. 2022;135(5):584–90.
Article
PubMed
PubMed Central
Google Scholar
Kamat AM, Hahn NM, Efstathiou JA, Lerner SP, Malmström PU, Choi W, et al. Bladder cancer. Lancet (London, England). 2016;388(10061):2796–810.
Article
Google Scholar
Berdik C. Unlocking bladder cancer. Nature. 2017;551(7679):S34–s5.
Article
CAS
PubMed
Google Scholar
Ploussard G, Shariat SF, Dragomir A, Kluth LA, Xylinas E, Masson-Lecomte A, et al. Conditional survival after radical cystectomy for bladder cancer: evidence for a patient changing risk profile over time. Eur Urol. 2014;66(2):361–70.
Article
PubMed
Google Scholar
Pei L, Melmed S. Isolation and characterization of a pituitary tumor-transforming gene (PTTG). Mol Endocrinol (Baltimore, Md). 1997;11(4):433–41.
Article
CAS
Google Scholar
Cho-Rok J, Yoo J, Jang YJ, Kim S, Chu IS, Yeom YI, et al. Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo. Hepatology (Baltimore, Md). 2006;43(5):1042–52.
Article
CAS
Google Scholar
Fu D, Zhang Y, Cui H. Long noncoding RNA CCAT2 is activated by E2F1 and exerts oncogenic properties by interacting with PTTG1 in pituitary adenomas. Am J Cancer Res. 2018;8(2):245–55.
CAS
PubMed
PubMed Central
Google Scholar
Tsai SJ, Lin SJ, Cheng YM, Chen HM, Wing LY. Expression and functional analysis of pituitary tumor transforming gene-1 [corrected] in uterine leiomyomas. J Clin Endocrinol Metab. 2005;90(6):3715–23.
Article
CAS
PubMed
Google Scholar
Solbach C, Roller M, Fellbaum C, Nicoletti M, Kaufmann M. PTTG mRNA expression in primary breast cancer: a prognostic marker for lymph node invasion and tumor recurrence. Breast (Edinburgh, Scotland). 2004;13(1):80–1.
Article
Google Scholar
Parte S, Virant-Klun I, Patankar M, Batra SK, Straughn A, Kakar SS. PTTG1: a Unique Regulator of Stem/Cancer Stem Cells in the Ovary and Ovarian Cancer. Stem Cell Rev Rep. 2019;15(6):866–79.
Article
CAS
PubMed
Google Scholar
Repo H, Gurvits N, Löyttyniemi E, Nykänen M, Lintunen M, Karra H, et al. PTTG1-interacting protein (PTTG1IP/PBF) predicts breast cancer survival. BMC Cancer. 2017;17(1):705.
Article
PubMed
PubMed Central
CAS
Google Scholar
Zou H, McGarry TJ, Bernal T, Kirschner MW. Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science (New York, NY). 1999;285(5426):418–22.
Article
CAS
Google Scholar
Heaney AP, Nelson V, Fernando M, Horwitz G. Transforming events in thyroid tumorigenesis and their association with follicular lesions. J Clin Endocrinol Metab. 2001;86(10):5025–32.
Article
CAS
PubMed
Google Scholar
Ren Q, Jin B. The clinical value and biological function of PTTG1 in colorectal cancer. Biomed Pharmacother. 2017;89:108–15.
Article
CAS
PubMed
Google Scholar
Ito T, Shimada Y, Kan T, David S, Cheng Y, Mori Y, et al. Pituitary tumor-transforming 1 increases cell motility and promotes lymph node metastasis in esophageal squamous cell carcinoma. Cancer Res. 2008;68(9):3214–24.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wang F, Liu Y, Chen Y. Pituitary tumor transforming gene-1 in non-small cell lung cancer: Clinicopathological and immunohistochemical analysis. Biomed Pharmacother. 2016;84:1595–600.
Article
CAS
PubMed
Google Scholar
Tsherniak A, Vazquez F, Montgomery PG, Weir BA, Kryukov G, Cowley GS, et al. Defining a Cancer Dependency Map. Cell. 2017;170(3):564–76.e16.
Article
CAS
PubMed
PubMed Central
Google Scholar
Vazquez F, Sellers WR. Are CRISPR screens providing the next generation of therapeutic targets? Cancer Res. 2021;81(23):5806–9.
Article
CAS
PubMed
Google Scholar
Li J, Yuan S, Norgard RJ, Yan F, Sun YH, Kim IK, et al. Epigenetic and transcriptional control of the epidermal growth factor receptor regulates the tumor immune microenvironment in pancreatic cancer. Cancer Disc. 2021;11(3):736–53.
Article
Google Scholar
Becht E, Giraldo NA, Lacroix L, Buttard B, Elarouci N, Petitprez F, et al. Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression. Genome Biol. 2016;17(1):218.
Article
PubMed
PubMed Central
CAS
Google Scholar
Geistlinger L, Oh S, Ramos M, Schiffer L, LaRue RS, Henzler CM, et al. Multiomic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinoma. Cancer Res. 2020;80(20):4335–45.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lai H, Cheng X, Liu Q, Luo W, Liu M, Zhang M, et al. Single-cell RNA sequencing reveals the epithelial cell heterogeneity and invasive subpopulation in human bladder cancer. Int J Cancer. 2021;149(12):2099–115.
Article
CAS
PubMed
Google Scholar
Davis CA, Hitz BC, Sloan CA, Chan ET, Davidson JM, Gabdank I, et al. The Encyclopedia of DNA elements (ENCODE): data portal update. Nucleic Acids Res. 2018;46(D1):D794–d801.
Article
CAS
PubMed
Google Scholar
Zheng R, Wan C, Mei S, Qin Q, Wu Q, Sun H, et al. Cistrome Data Browser: expanded datasets and new tools for gene regulatory analysis. Nucleic Acids Res. 2019;47(D1):D729–d35.
Article
CAS
PubMed
Google Scholar
Szklarczyk D, Gable AL, Lyon D, Junge A, Wyder S, Huerta-Cepas J, et al. STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets. Nucleic Acids Res. 2019;47(D1):D607–d13.
Article
CAS
PubMed
Google Scholar
Modhukur V, Iljasenko T, Metsalu T, Lokk K, Laisk-Podar T, Vilo J. MethSurv: a web tool to perform multivariable survival analysis using DNA methylation data. Epigenomics. 2018;10(3):277–88.
Article
CAS
PubMed
Google Scholar
Anuraga G, Wang WJ, Phan NN, An Ton NT, Ta HDK, Berenice Prayugo F, et al. Potential prognostic biomarkers of NIMA (Never in Mitosis, Gene A)-Related Kinase (NEK) family members in breast cancer. J Personalized Med. 2021;11(11):1089.
Article
Google Scholar
Zheng Q, Wang Z, Zhang M, Yu Y, Chen R, Lu T, et al. Prognostic value of SEC61G in lung adenocarcinoma: a comprehensive study based on bioinformatics and in vitro validation. BMC Cancer. 2021;21(1):1216.
Article
CAS
PubMed
PubMed Central
Google Scholar
Subramanian A, Narayan R, Corsello SM, Peck DD, Natoli TE, Lu X, et al. A next generation connectivity map: l1000 platform and the first 1,000,000 profiles. Cell. 2017;171(6):1437–52.e17.
Article
CAS
PubMed
PubMed Central
Google Scholar
Shah U, Patel A, Patel S, Patel M, Patel A, Patel S, et al. Role of natural and synthetic flavonoids as potential aromatase inhibitors in breast cancer: structure-activity relationship perspective. Anti Cancer Agents Med Chem. 2022;22(11):2063–79.
Article
Google Scholar
Kharb R, Haider K, Neha K, Yar MS. Aromatase inhibitors: Role in postmenopausal breast cancer. Arch Pharm. 2020;353(8):e2000081.
Article
CAS
Google Scholar
Mallery SR, Wang D, Santiago B, Pei P, Bissonnette C, Jayawardena JA, et al. Fenretinide, tocilizumab, and reparixin provide multifaceted disruption of oral squamous cell carcinoma stem cell properties: implications for tertiary chemoprevention. Mol Cancer Ther. 2019;18(12):2308–20.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hernández-Camarero P, López-Ruiz E, Marchal JA, Perán M. Cancer: a mirrored room between tumor bulk and tumor microenvironment. J Exp Clin Cancer Res CR. 2021;40(1):217.
Article
PubMed
Google Scholar
Khalaf K, Hana D, Chou JT, Singh C, Mackiewicz A, Kaczmarek M. Aspects of the tumor microenvironment involved in immune resistance and drug resistance. Front Immunol. 2021;12:656364.
Article
PubMed
PubMed Central
CAS
Google Scholar
Sivori S, Pende D, Quatrini L, Pietra G, Della Chiesa M, Vacca P, et al. NK cells and ILCs in tumor immunotherapy. Mol Asp Med. 2021;80:100870.
Article
CAS
Google Scholar
Levy D, Ferreira M, Reichert CO, de Almeida LV, Brocardo G, Lage L, et al. Cell cycle changes, DNA ploidy, and PTTG1 gene expression in HTLV-1 patients. Front Microbiol. 2020;11:1778.
Article
PubMed
PubMed Central
Google Scholar
Stoika R, Melmed S. Expression and function of pituitary tumour transforming gene for T-lymphocyte activation. Br J Haematol. 2002;119(4):1070–4.
Article
CAS
PubMed
Google Scholar
Chiriva-Internati M, Mirandola L, Figueroa JA, Yu Y, Grizzi F, Kim M, et al. Selective expression and immunogenicity of the cancer/testis antigens SP17, AKAP4 and PTTG1 in non-small cell lung cancer: new candidates for active immunotherapy. Chest. 2014.
Tian X, Xu WH, Xu FJ, Li H, Anwaier A, Wang HK, et al. Identification of prognostic biomarkers in papillary renal cell carcinoma and PTTG1 may serve as a biomarker for predicting immunotherapy response. Ann Med. 2022;54(1):211–26.
Article
CAS
PubMed
PubMed Central
Google Scholar
Spachmann PJ, Azzolina V, Weber F, Evert M, Eckstein M, Denzinger S, et al. Loss of CHEK2 Predicts Progression in Stage pT1 Non-Muscle-Invasive Bladder Cancer (NMIBC). Pathol Oncol Res. 2020;26(3):1625–32.
Article
CAS
PubMed
Google Scholar
Słojewski M, Złowocka E, Cybulski C, Górski B, Debniak T, Wokołorczyk D, et al. CHEK2 germline mutations correlate with recurrence rate in patients with superficial bladder cancer. Ann Acad Med Stetin. 2008;54(3):115–21.
PubMed
Google Scholar
Sinha S, Bheemsetty VA, Inamdar MS. A double helical motif in OCIAD2 is essential for its localization, interactions and STAT3 activation. Sci Rep. 2018;8(1):7362.
Article
PubMed
PubMed Central
CAS
Google Scholar
Liu Y, Song C, Ni H, Jiao W, Gan W, Dong X, et al. UBE2L3, a susceptibility gene that plays oncogenic role in hepatitis B-related hepatocellular carcinoma. J Viral Hepat. 2018;25(11):1363–71.
Article
CAS
PubMed
Google Scholar
Cui Z, Sun S, Li J, Li J, Sha T, He J, et al. UBE2L3 promotes squamous cell carcinoma progression in the oral cavity and hypopharynx via activating the NF-κB signaling by increasing IκBα degradation. Cell Biol Int. 2022.
Tao NN, Zhang ZZ, Ren JH, Zhang J, Zhou YJ, Wai Wong VK, et al. Overexpression of ubiquitin-conjugating enzyme E2 L3 in hepatocellular carcinoma potentiates apoptosis evasion by inhibiting the GSK3β/p65 pathway. Cancer Lett. 2020;481:1–14.
Article
CAS
PubMed
Google Scholar
Zeng H, Li T, Zhai D, Bi J, Kuang X, Lu S, et al. ZNF367-induced transcriptional activation of KIF15 accelerates the progression of breast cancer. Int J Biol Sci. 2020;16(12):2084–93.
Article
CAS
PubMed
PubMed Central
Google Scholar
Tong Y, Eigler T. Transcriptional targets for pituitary tumor-transforming gene-1. J Mol Endocrinol. 2009;43(5):179–85.
Article
CAS
PubMed
Google Scholar
Pei L. Identification of c-myc as a down-stream target for pituitary tumor-transforming gene. J Biol Chem. 2001;276(11):8484–91.
Article
CAS
PubMed
Google Scholar
Lin X, Yang Y, Guo Y, Liu H, Jiang J, Zheng F, et al. PTTG1 is involved in TNF-α-related hepatocellular carcinoma via the induction of c-myc. Cancer Med. 2019;8(12):5702–15.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bernal JA, Luna R, Espina A, Lázaro I, Ramos-Morales F, Romero F, et al. Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis. Nat Genet. 2002;32(2):306–11.
Article
CAS
PubMed
Google Scholar
Tong Y, Tan Y, Zhou C, Melmed S. Pituitary tumor transforming gene interacts with Sp1 to modulate G1/S cell phase transition. Oncogene. 2007;26(38):5596–605.
Article
CAS
PubMed
PubMed Central
Google Scholar