Fig. 6From: Clinical significance and potential regulatory mechanism of overexpression of pituitary tumor-transforming gene transcription factor in bladder cancerPTTG1 as an unfavorable prognostic biomarker in bladder carcinoma. A summary receiver operating characteristic curve was used to evaluate the comprehensive discriminatory ability of PTTG1 in bladder carcinoma. Intriguingly, PTTG1 displayed a strong ability in differentiating bladder carcinoma tissue samples from normal bladder tissue samples (AUC > 0.9) (A). Kaplan-Meier survival analysis was performed to determine the prognostic value of PTTG1 in bladder carcinoma. Higher PTTG1 mRNA levels presaged worse overall survival probability (HR > 1, P < 0.05) (B) and poorer disease-free survival outcomes (HR > 1, P > 0.05) (C). A time-dependent receiver operating characteristic curve was utilized to evaluate the 1-year, 2-year, and 3-year survival rates of bladder carcinoma patients (D)Back to article page