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Fig. 11 | BMC Cancer

Fig. 11

From: Clinical significance and potential regulatory mechanism of overexpression of pituitary tumor-transforming gene transcription factor in bladder cancer

Fig. 11

Functional enrichment of PTTG1 transcriptional targets in BLCA tissue. Differentially expressed genes (DEGs) associated with CHEK2, OCIAD2, UBE2L3, and ZNF367 were identified from the TCGA-BLCA cohort study. The prospective biological functions of these PTTG1 targets were annotated. A. CHEK2-related DEGs were significantly enriched in the antibacterial humoral response. B. OCIAD2-related DEGs were significantly enriched in the complement activation (classical pathway). C. UBE2L3-related DEGs were significantly enriched in the phagocytosis and recognition. D. ZNF367-related DEGs were significantly enriched in the cell cycle pathway. BLCA, bladder carcinoma

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BMC Cancer

ISSN: 1471-2407

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