DiPaola RS, Patel J, Rafi MM: Targeting apoptosis in prostate cancer. Hematol Oncol Clin North Am. 2001, 15 (3): 509-524. 10.1016/S0889-8588(05)70229-X.
Article
CAS
PubMed
Google Scholar
Xu L, Frederik P, Pirollo KF, Tang WH, Rait A, Xiang LM, Huang W, Cruz I, Yin Y, Chang EH: Self-assembly of a virus-mimicking nanostructure system for efficient tumor-targeted gene delivery. Hum Gene Ther. 2002, 13 (3): 469-481. 10.1089/10430340252792594.
Article
CAS
PubMed
Google Scholar
Bucur O, Ray S, Bucur MC, Almasan A: APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in prostate cancer therapy. Front Biosci. 2006, 11: 1549-1568. 10.2741/1903.
Article
CAS
PubMed
Google Scholar
Shankar S, Siddiqui I, Srivastava RK: Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells. Mol Cell Biochem. 2007, 304 (1-2): 273-285. 10.1007/s11010-007-9510-x.
Article
CAS
PubMed
Google Scholar
Steele LP, Georgopoulos NT, Southgate J, Selby PJ, Trejdosiewicz LK: Differential susceptibility to TRAIL of normal versus malignant human urothelial cells. Cell Death Differ. 2006, 13 (9): 1564-1576. 10.1038/sj.cdd.4401846.
Article
CAS
PubMed
Google Scholar
Almasan A, Ashkenazi A: Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy. Cytokine Growth Factor Rev. 2003, 14 (3-4): 337-348. 10.1016/S1359-6101(03)00029-7.
Article
CAS
PubMed
Google Scholar
Ng CP, Zisman A, Bonavida B: Synergy is achieved by complementation with Apo2L/TRAIL and actinomycin D in Apo2L/TRAIL-mediated apoptosis of prostate cancer cells: role of XIAP in resistance. Prostate. 2002, 53 (4): 286-299. 10.1002/pros.10155.
Article
CAS
PubMed
Google Scholar
Knight MJ, Riffkin CD, Ekert PG, Ashley DM, Hawkins CJ: Caspase-8 levels affect necessity for mitochondrial amplification in death ligand-induced glioma cell apoptosis. Mol Carcinog. 2004, 39 (3): 173-182. 10.1002/mc.20011.
Article
CAS
PubMed
Google Scholar
Fulda S, Meyer E, Debatin KM: Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression. Oncogene. 2002, 21 (15): 2283-2294. 10.1038/sj.onc.1205258.
Article
CAS
PubMed
Google Scholar
Kruyt FA: TRAIL and cancer therapy. Cancer Lett. 2008, 263 (1): 14-25. 10.1016/j.canlet.2008.02.003.
Article
CAS
PubMed
Google Scholar
Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X, Harran PG: A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science. 2004, 305 (5689): 1471-1474. 10.1126/science.1098231.
Article
CAS
PubMed
Google Scholar
Cummins JM, Kohli M, Rago C, Kinzler KW, Vogelstein B, Bunz F: X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells. Cancer Res. 2004, 64 (9): 3006-3008. 10.1158/0008-5472.CAN-04-0046.
Article
CAS
PubMed
Google Scholar
Fulda S, Wick W, Weller M, Debatin KM: Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat Med. 2002, 8 (8): 808-815.
CAS
PubMed
Google Scholar
Schimmer AD, Welsh K, Pinilla C, Wang Z, Krajewska M, Bonneau MJ, Pedersen IM, Kitada S, Scott FL, Bailly-Maitre B, Glinsky G, Scudiero D, Sausville E, Salvesen G, Nefzi A, Ostresh JM, Houghten RA, Reed JC: Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity. Cancer Cell. 2004, 5 (1): 25-35. 10.1016/S1535-6108(03)00332-5.
Article
CAS
PubMed
Google Scholar
Gaither A, Porter D, Yao Y, Borawski J, Yang G, Donovan J, Sage D, Slisz J, Tran M, Straub C, Ramsey T, Iourgenko V, Huang A, Chen Y, Schlegel R, Labow M, Fawell S, Sellers WR, Zawel L: A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling. Cancer Res. 2007, 67 (24): 11493-11498. 10.1158/0008-5472.CAN-07-5173.
Article
CAS
PubMed
Google Scholar
Chauhan D, Neri P, Velankar M, Podar K, Hideshima T, Fulciniti M, Tassone P, Raje N, Mitsiades C, Mitsiades N, Richardson P, Zawel L, Tran M, Munshi N, Anderson KC: Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM). Blood. 2007, 109 (3): 1220-1227. 10.1182/blood-2006-04-015149.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chawla-Sarkar M, Bae SI, Reu FJ, Jacobs BS, Lindner DJ, Borden EC: Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. Cell Death Differ. 2004, 11 (8): 915-923. 10.1038/sj.cdd.4401416.
Article
CAS
PubMed
Google Scholar
Zhang L, Fang B: Mechanisms of resistance to TRAIL-induced apoptosis in cancer. Cancer Gene Ther. 2005, 12 (3): 228-237. 10.1038/sj.cgt.7700792.
Article
CAS
PubMed
Google Scholar
Sarkar FH, Li Y: NF-kappaB: a potential target for cancer chemoprevention and therapy. Front Biosci. 2008, 13: 2950-2959. 10.2741/2900.
Article
CAS
PubMed
Google Scholar
Pahl HL: Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene. 1999, 18 (49): 6853-6866. 10.1038/sj.onc.1203239.
Article
CAS
PubMed
Google Scholar
Falschlehner C, Emmerich CH, Gerlach B, Walczak H: TRAIL signalling: decisions between life and death. Int J Biochem Cell Biol. 2007, 39 (7-8): 1462-1475. 10.1016/j.biocel.2007.02.007.
Article
CAS
PubMed
Google Scholar
Suh J, Rabson AB: NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon?. J Cell Biochem. 2004, 91 (1): 100-117. 10.1002/jcb.10729.
Article
CAS
PubMed
Google Scholar
Dai Y, Lawrence TS, Xu L: Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor-kappa B. Am J Transl Res. 2009, 1 (1): 4-18.
Google Scholar
Irmler M, Steiner V, Ruegg C, Wajant H, Tschopp J: Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis. FEBS Lett. 2000, 468 (2-3): 129-133. 10.1016/S0014-5793(00)01206-0.
Article
CAS
PubMed
Google Scholar
Holcik M, Gibson H, Korneluk RG: XIAP: apoptotic brake and promising therapeutic target. Apoptosis. 2001, 6 (4): 253-261. 10.1023/A:1011379307472.
Article
CAS
PubMed
Google Scholar
Wu G, Chai J, Suber TL, Wu JW, Du C, Wang X, Shi Y: Structural basis of IAP recognition by Smac/DIABLO. Nature. 2000, 408 (6815): 1008-1012. 10.1038/35050012.
Article
CAS
PubMed
Google Scholar
Liu Z, Sun C, Olejniczak ET, Meadows RP, Betz SF, Oost T, Herrmann J, Wu JC, Fesik SW: Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature. 2000, 408 (6815): 1004-1008. 10.1038/35050006.
Article
CAS
PubMed
Google Scholar
Srinivasula SM, Ashwell JD: IAPs: What's in a Name?. Mol Cell. 2008, 30: 123-135. 10.1016/j.molcel.2008.03.008.
Article
CAS
PubMed
PubMed Central
Google Scholar
Varfolomeev E, Blankenship JW, Wayson SM, Fedorova AV, Kayagaki N, Garg P, Zobel K, Dynek JN, Elliott LO, Wallweber HJ, Flygare JA, Fairbrother WJ, Deshayes K, Dixit VM, Vucic D: IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell. 2007, 131 (4): 669-681. 10.1016/j.cell.2007.10.030.
Article
CAS
PubMed
Google Scholar
Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, Benetatos CA, Chunduru SK, Condon SM, McKinlay M, Brink R, Leverkus M, Tergaonkar V, Schneider P, Callus BA, Koentgen F, Vaux DL, Silke J: IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell. 2007, 131 (4): 682-693. 10.1016/j.cell.2007.10.037.
Article
CAS
PubMed
Google Scholar
Petersen SL, Wang L, Yalcin-Chin A, Li L, Peyton M, Minna J, Harran P, Wang X: Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell. 2007, 12 (5): 445-456. 10.1016/j.ccr.2007.08.029.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bockbrader KM, Tan M, Sun Y: A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells. Oncogene. 2005, 24 (49): 7381-7388. 10.1038/sj.onc.1208888.
Article
CAS
PubMed
Google Scholar
Petrucci E, Pasquini L, Petronelli A, Saulle E, Mariani G, Riccioni R, Biffoni M, Ferretti G, Benedetti-Panici P, Cognetti F, Scambia G, Humphreys R, Peschle C, Testa U: A small molecule Smac mimic potentiates TRAIL-mediated cell death of ovarian cancer cells. Gynecol Oncol. 2007, 105 (2): 481-492. 10.1016/j.ygyno.2007.01.011.
Article
CAS
PubMed
Google Scholar
Sun H, Nikolovska-Coleska Z, Yang CY, Xu L, Liu M, Tomita Y, Pan H, Yoshioka Y, Krajewski K, Roller PP, Wang S: Structure-based design of potent, conformationally constrained Smac mimetics. J Am Chem Soc. 2004, 126 (51): 16686-16687. 10.1021/ja047438+.
Article
CAS
PubMed
Google Scholar
Sun H, Nikolovska-Coleska Z, Yang CY, Xu L, Tomita Y, Krajewski K, Roller PP, Wang S: Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site. J Med Chem. 2004, 47 (17): 4147-4150. 10.1021/jm0499108.
Article
CAS
PubMed
Google Scholar
Sun H, Nikolovska-Coleska Z, Lu J, Qiu S, Yang CY, Gao W, Meagher J, Stuckey J, Wang S: Design, synthesis, and evaluation of a potent, cell-permeable, conformationally constrained second mitochondria derived activator of caspase (Smac) mimetic. J Med Chem. 2006, 49 (26): 7916-7920. 10.1021/jm061108d.
Article
CAS
PubMed
Google Scholar
Jia G, Zhan Y, Wu D, Meng Y, Xu L: An improved ultrasound-assisted extraction process of gossypol acetic acid from cottonseed soapstock. AIChE J. 2009, 55 (3): 797-806. 10.1002/aic.11700.
Article
CAS
Google Scholar
Dai Y, Liu M, Tang W, Desano J, Burstein E, Davis M, Pienta K, Lawrence T, Xu L: Molecularly targeted radiosensitization of human prostate cancer by modulating inhibitor of apoptosis. Clin Cancer Res. 2008, 14 (23): 7701-7710. 10.1158/1078-0432.CCR-08-0188.
Article
CAS
PubMed
PubMed Central
Google Scholar
Burstein E, Hoberg JE, Wilkinson AS, Rumble JM, Csomos RA, Komarck CM, Maine GN, Wilkinson JC, Mayo MW, Duckett CS: COMMD proteins, a novel family of structural and functional homologs of MURR1. J Biol Chem. 2005, 280 (23): 22222-22232. 10.1074/jbc.M501928200.
Article
CAS
PubMed
Google Scholar
Maine GN, Burstein E: COMMD proteins and the control of the NF kappa B pathway. Cell Cycle. 2007, 6 (6): 672-676.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ji Q, Hao X, Meng Y, Zhang M, Desano J, Fan D, Xu L: Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer. 2008, 8 (1): 266-10.1186/1471-2407-8-266.
Article
PubMed
PubMed Central
Google Scholar
Dai Y, DeSano JT, Meng Y, Ji Q, Ljungman M, Lawrence TS, Xu L: Celastrol potentiates radiotherapy by impairment of DNA damage processing in human prostate cancer. Int J Radiat Oncol Biol Phys. 2009, 74 (4): 1217-1225.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ng CP, Bonavida B: X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO). Mol Cancer Ther. 2002, 1 (12): 1051-1058.
CAS
PubMed
Google Scholar
Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S: Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database. J Med Chem. 2004, 47 (10): 2430-2440. 10.1021/jm030420+.
Article
CAS
PubMed
Google Scholar
Naumann U, Bahr O, Wolburg H, Altenberend S, Wick W, Liston P, Ashkenazi A, Weller M: Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice. Gene Ther. 2007, 14 (2): 147-161. 10.1038/sj.gt.3303010.
CAS
PubMed
Google Scholar
Mitsiades CS, Mitsiades N, Poulaki V, Schlossman R, Akiyama M, Chauhan D, Hideshima T, Treon SP, Munshi NC, Richardson PG, Anderson KC: Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications. Oncogene. 2002, 21 (37): 5673-5683. 10.1038/sj.onc.1205664.
Article
CAS
PubMed
Google Scholar
Amantana A, London CA, Iversen PL, Devi GR: X-linked inhibitor of apoptosis protein inhibition induces apoptosis and enhances chemotherapy sensitivity in human prostate cancer cells. Mol Cancer Ther. 2004, 3 (6): 699-707.
CAS
PubMed
Google Scholar
Mao HL, Liu PS, Zheng JF, Zhang PH, Zhou LG, Xin G, Liu C: Transfection of Smac/DIABLO sensitizes drug-resistant tumor cells to TRAIL or paclitaxel-induced apoptosis in vitro. Pharmacol Res. 2007, 56 (6): 483-492. 10.1016/j.phrs.2007.09.010.
Article
CAS
PubMed
Google Scholar
Morales JC, Ruiz-Magana MJ, Ruiz-Ruiz C: Regulation of the resistance to TRAIL-induced apoptosis in human primary T lymphocytes: role of NF-kappaB inhibition. Mol Immunol. 2007, 44 (10): 2587-2597. 10.1016/j.molimm.2006.12.015.
Article
CAS
PubMed
Google Scholar
Braeuer SJ, Buneker C, Mohr A, Zwacka RM: Constitutively activated nuclear factor-kappaB, but not induced NF-kappaB, leads to TRAIL resistance by up-regulation of X-linked inhibitor of apoptosis protein in human cancer cells. Mol Cancer Res. 2006, 4 (10): 715-728. 10.1158/1541-7786.MCR-05-0231.
Article
CAS
PubMed
Google Scholar
Kuai J, Nickbarg E, Wooters J, Qiu Y, Wang J, Lin LL: Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis. J Biol Chem. 2003, 278 (16): 14363-14369. 10.1074/jbc.M208672200.
Article
CAS
PubMed
Google Scholar
Samuel T, Welsh K, Lober T, Togo SH, Zapata JM, Reed JC: Distinct BIR domains of cIAP1 mediate binding to and ubiquitination of tumor necrosis factor receptor-associated factor 2 and second mitochondrial activator of caspases. J Biol Chem. 2006, 281 (2): 1080-1090. 10.1074/jbc.M509381200.
Article
CAS
PubMed
Google Scholar
Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Barker PA: cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell. 2008, 30 (6): 689-700. 10.1016/j.molcel.2008.05.014.
Article
CAS
PubMed
Google Scholar
Ahn KS, Sethi G, Aggarwal BB: Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Mol Pharmacol. 2007, 71 (1): 209-219. 10.1124/mol.106.028787.
Article
CAS
PubMed
Google Scholar
Johnstone RW, Ruefli AA, Lowe SW: Apoptosis: a link between cancer genetics and chemotherapy. Cell. 2002, 108 (2): 153-164. 10.1016/S0092-8674(02)00625-6.
Article
CAS
PubMed
Google Scholar