Mundy GR: Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer. 2002, 2 (8): 584-593. 10.1038/nrc867.
Article
CAS
PubMed
Google Scholar
Weilbaecher KN, Guise TA, McCauley LK: Cancer to bone: a fatal attraction. Nat Rev Cancer. 2011, 11 (6): 411-425. 10.1038/nrc3055.
Article
CAS
PubMed
PubMed Central
Google Scholar
Solakoglu O, Maierhofer C, Lahr G, Breit E, Scheunemann P, Heumos I, Pichlmeier U, Schlimok G, Oberneder R, Kollermann MW, et al: Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors. Proc Natl Acad Sci U S A. 2002, 99 (4): 2246-2251. 10.1073/pnas.042372199.
Article
CAS
PubMed
PubMed Central
Google Scholar
Roodman GD: Mechanisms of bone metastasis. N Engl J Med. 2004, 350 (16): 1655-1664. 10.1056/NEJMra030831.
Article
CAS
PubMed
Google Scholar
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordon-Cardo C, Guise TA, Massague J: A multigenic program mediating breast cancer metastasis to bone. Cancer Cell. 2003, 3 (6): 537-549. 10.1016/S1535-6108(03)00132-6.
Article
CAS
PubMed
Google Scholar
Mancino AT, Klimberg VS, Yamamoto M, Manolagas SC, Abe E: Breast cancer increases osteoclastogenesis by secreting M-CSF and upregulating RANKL in stromal cells. J Surg Res. 2001, 100 (1): 18-24. 10.1006/jsre.2001.6204.
Article
CAS
PubMed
Google Scholar
Pederson L, Winding B, Foged NT, Spelsberg TC, Oursler MJ: Identification of breast cancer cell line-derived paracrine factors that stimulate osteoclast activity. Cancer Res. 1999, 59 (22): 5849-5855.
CAS
PubMed
Google Scholar
Yamasaki K, Taga T, Hirata Y, Yawata H, Kawanishi Y, Seed B, Taniguchi T, Hirano T, Kishimoto T: Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor. Science. 1988, 241 (4867): 825-828. 10.1126/science.3136546.
Article
CAS
PubMed
Google Scholar
Hilton DJ, Hilton AA, Raicevic A, Rakar S, Harrison-Smith M, Gough NM, Begley CG, Metcalf D, Nicola NA, Willson TA: Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction. EMBO J. 1994, 13 (20): 4765-4775.
CAS
PubMed
PubMed Central
Google Scholar
Leng SX, Elias JA: Interleukin-11. Int J Biochem Cell Biol. 1997, 29 (8–9): 1059-1062.
Article
CAS
PubMed
Google Scholar
Morinaga Y, Fujita N, Ohishi K, Tsuruo T: Stimulation of interleukin-11 production from osteoblast-like cells by transforming growth factor-beta and tumor cell factors. Int J of cancer J Int du cancer. 1997, 71 (3): 422-428. 10.1002/(SICI)1097-0215(19970502)71:3<422::AID-IJC20>3.0.CO;2-G.
Article
CAS
Google Scholar
Hughes FJ, Howells GL: Interleukin-11 inhibits bone formation in vitro. Calcif Tissue Int. 1993, 53 (5): 362-364. 10.1007/BF01351844.
Article
CAS
PubMed
Google Scholar
Lacroix M, Siwek B, Marie PJ, Body JJ: Production and regulation of interleukin-11 by breast cancer cells. Cancer Lett. 1998, 127 (1–2): 29-35.
Article
CAS
PubMed
Google Scholar
Sims NA, Jenkins BJ, Nakamura A, Quinn JM, Li R, Gillespie MT, Ernst M, Robb L, Martin TJ: Interleukin-11 receptor signaling is required for normal bone remodeling. J Bone Miner Res. 2005, 20 (7): 1093-1102. 10.1359/JBMR.050209.
Article
CAS
PubMed
Google Scholar
Kudo O, Sabokbar A, Pocock A, Itonaga I, Fujikawa Y, Athanasou NA: Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism. Bone. 2003, 32 (1): 1-7. 10.1016/S8756-3282(02)00915-8.
Article
CAS
PubMed
Google Scholar
Girasole G, Passeri G, Jilka RL, Manolagas SC: Interleukin-11: a new cytokine critical for osteoclast development. J Clin Invest. 1994, 93 (4): 1516-1524. 10.1172/JCI117130.
Article
CAS
PubMed
PubMed Central
Google Scholar
Morgan H, Tumber A, Hill PA: Breast cancer cells induce osteoclast formation by stimulating host IL-11 production and downregulating granulocyte/macrophage colony-stimulating factor. Int J of cancer J Int du cancer. 2004, 109 (5): 653-660. 10.1002/ijc.20056.
Article
CAS
Google Scholar
Hill PA, Tumber A, Papaioannou S, Meikle MC: The cellular actions of interleukin-11 on bone resorption in vitro. Endocrinology. 1998, 139 (4): 1564-1572. 10.1210/en.139.4.1564.
Article
CAS
PubMed
Google Scholar
McHugh KP, Hodivala-Dilke K, Zheng MH, Namba N, Lam J, Novack D, Feng X, Ross FP, Hynes RO, Teitelbaum SL: Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts. J Clin Invest. 2000, 105 (4): 433-440. 10.1172/JCI8905.
Article
CAS
PubMed
PubMed Central
Google Scholar
Morinaga Y, Fujita N, Ohishi K, Zhang Y, Tsuruo T: Suppression of interleukin-11-mediated bone resorption by cyclooxygenases inhibitors. J Cell Physiol. 1998, 175 (3): 247-254. 10.1002/(SICI)1097-4652(199806)175:3<247::AID-JCP2>3.0.CO;2-O.
Article
CAS
PubMed
Google Scholar
Ma T, Miyanishi K, Suen A, Epstein NJ, Tomita T, Smith RL, Goodman SB: Human interleukin-1-induced murine osteoclastogenesis is dependent on RANKL, but independent of TNF-alpha. Cytokine. 2004, 26 (3): 138-144. 10.1016/j.cyto.2004.02.001.
Article
CAS
PubMed
Google Scholar
Wei S, Kitaura H, Zhou P, Ross FP, Teitelbaum SL: IL-1 mediates TNF-induced osteoclastogenesis. J Clin Invest. 2005, 115 (2): 282-290.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP, Teitelbaum SL: TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest. 2000, 106 (12): 1481-1488. 10.1172/JCI11176.
Article
CAS
PubMed
PubMed Central
Google Scholar
Li P, Schwarz EM, O’Keefe RJ, Ma L, Boyce BF, Xing L: RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis. J Bone Miner Res. 2004, 19 (2): 207-213.
Article
CAS
PubMed
Google Scholar
Jules J, Shi Z, Liu J, Xu D, Wang S, Feng X: Receptor activator of NF-{kappa}B (RANK) cytoplasmic IVVY535-538 motif plays an essential role in tumor necrosis factor-{alpha} (TNF)-mediated osteoclastogenesis. J Biol Chem. 2010, 285 (48): 37427-37435. 10.1074/jbc.M110.149484.
Article
CAS
PubMed
PubMed Central
Google Scholar
Jules J, Zhang P, Ashley JW, Wei S, Shi Z, Liu J, Michalek SM, Feng X: Molecular basis of requirement of receptor activator of nuclear factor kappaB signaling for interleukin 1-mediated osteoclastogenesis. J Biol Chem. 2012, 287 (19): 15728-15738. 10.1074/jbc.M111.296228.
Article
CAS
PubMed
PubMed Central
Google Scholar
Crichton MB, Nichols JE, Zhao Y, Bulun SE, Simpson ER: Expression of transcripts of interleukin-6 and related cytokines by human breast tumors, breast cancer cells, and adipose stromal cells. Mol Cell Endocrinol. 1996, 118 (1–2): 215-220.
Article
CAS
PubMed
Google Scholar
Sotiriou C, Lacroix M, Lagneaux L, Berchem G, Body JJ: The aspirin metabolite salicylate inhibits breast cancer cells growth and their synthesis of the osteolytic cytokines interleukins-6 and −11. Anticancer Res. 1999, 19 (4B): 2997-3006.
CAS
PubMed
Google Scholar
Sotiriou C, Lacroix M, Lespagnard L, Larsimont D, Paesmans M, Body JJ: Interleukins-6 and −11 expression in primary breast cancer and subsequent development of bone metastases. Cancer Lett. 2001, 169 (1): 87-95. 10.1016/S0304-3835(01)00524-9.
Article
CAS
PubMed
Google Scholar
Kang Y, He W, Tulley S, Gupta GP, Serganova I, Chen CR, Manova-Todorova K, Blasberg R, Gerald WL, Massague J: Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. Proc Natl Acad Sci U S A. 2005, 102 (39): 13909-13914. 10.1073/pnas.0506517102.
Article
CAS
PubMed
PubMed Central
Google Scholar
Singh B, Berry JA, Shoher A, Lucci A: COX-2 induces IL-11 production in human breast cancer cells. J Surg Res. 2006, 131 (2): 267-275. 10.1016/j.jss.2005.11.582.
Article
CAS
PubMed
Google Scholar
Hanavadi S, Martin TA, Watkins G, Mansel RE, Jiang WG: Expression of interleukin 11 and its receptor and their prognostic value in human breast cancer. Ann Surg Oncol. 2006, 13 (6): 802-808. 10.1245/ASO.2006.05.028.
Article
PubMed
Google Scholar
Gupta J, Robbins J, Jilling T, Seth P: TGFbeta-dependent induction of interleukin-11 and interleukin-8 involves SMAD and p38 MAPK pathways in breast tumor models with varied bone metastases potential. Cancer Biol Ther. 2011, 11 (3): 311-316. 10.4161/cbt.11.3.14096.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pollari S, Kakonen RS, Mohammad KS, Rissanen JP, Halleen JM, Warri A, Nissinen L, Pihlavisto M, Marjamaki A, Perala M, et al: Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis. Mol Cancer Res. 2012, 10 (5): 597-604. 10.1158/1541-7786.MCR-11-0482.
Article
CAS
PubMed
Google Scholar
Romas E, Udagawa N, Zhou H, Tamura T, Saito M, Taga T, Hilton DJ, Suda T, Ng KW, Martin TJ: The role of gp130-mediated signals in osteoclast development: regulation of interleukin 11 production by osteoblasts and distribution of its receptor in bone marrow cultures. J Exp Med. 1996, 183 (6): 2581-2591. 10.1084/jem.183.6.2581.
Article
CAS
PubMed
Google Scholar
Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ: Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev. 1999, 20 (3): 345-357. 10.1210/er.20.3.345.
Article
CAS
PubMed
Google Scholar
Yasuda H, Shima N, Nakagawa N, Yamaguchi K, Kinosaki M, Goto M, Mochizuki SI, Tsuda E, Morinaga T, Udagawa N, et al: A novel molecular mechanism modulating osteoclast differentiation and function. Bone. 1999, 25 (1): 109-113. 10.1016/S8756-3282(99)00121-0.
Article
CAS
PubMed
Google Scholar