Hanahan D, Weinberg RA: The hallmarks of cancer. Cell. 2000, 100: 57-70. 10.1016/S0092-8674(00)81683-9.
Article
CAS
PubMed
Google Scholar
Herman JG, Baylin SB: Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med. 2003, 349: 2042-2054. 10.1056/NEJMra023075.
Article
CAS
PubMed
Google Scholar
Esteller M: Epigenetics in cancer. N Engl J Med. 2008, 358: 1148-1159. 10.1056/NEJMra072067.
Article
CAS
PubMed
Google Scholar
Goll MG, Bestor TH: Eukaryotic cytosine methyltransferases. Annu Rev Biochem. 2005, 74: 481-514. 10.1146/annurev.biochem.74.010904.153721.
Article
CAS
PubMed
Google Scholar
Bird A: DNA methylation patterns and epigenetic memory. Genes Dev. 2002, 16: 6-21. 10.1101/gad.947102.
Article
CAS
PubMed
Google Scholar
Santos FP, Kantarjian H, Garcia-Manero G, Issa JP, Ravandi F: Decitabine in the treatment of myelodysplastic syndromes. Expert Rev Anticancer Ther. 2010, 10: 9-22. 10.1586/era.09.164.
Article
CAS
PubMed
Google Scholar
Costello JF, Fruhwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lang JC, et al: Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet. 2000, 24: 132-138. 10.1038/72785.
Article
CAS
PubMed
Google Scholar
Esteller M, Corn PG, Baylin SB, Herman JG: A gene hypermethylation profile of human cancer. Cancer Res. 2001, 61: 3225-3229.
CAS
PubMed
Google Scholar
Paz MF, Fraga MF, Avila S, Guo M, Pollan M, Herman JG, Esteller M: A systematic profile of DNA methylation in human cancer cell lines. Cancer Res. 2003, 63: 1114-1121.
CAS
PubMed
Google Scholar
Rohrs S, Dirks WG, Meyer C, Marschalek R, Scherr M, Slany R, Wallace A, Drexler HG, Quentmeier H: Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia. Mol Cancer. 2009, 8: 86-10.1186/1476-4598-8-86.
Article
PubMed
PubMed Central
Google Scholar
Rohrs S, Romani J, Zaborski M, Drexler HG, Quentmeier H: Hypermethylation of Death-Associated Protein Kinase 1 differentiates natural killer cell lines from cell lines derived from T-acute lymphoblastic leukemia. Leukemia. 2009, 23: 1174-1176. 10.1038/leu.2009.5.
Article
CAS
PubMed
Google Scholar
Rahmatpanah FB, Carstens S, Guo J, Sjahputera O, Taylor KH, Duff D, Shi H, Davis JW, Hooshmand SI, Chitma-Matsiga R, et al: Differential DNA methylation patterns of small B-cell lymphoma subclasses with different clinical behavior. Leukemia. 2006, 20: 1855-1862. 10.1038/sj.leu.2404345.
Article
CAS
PubMed
Google Scholar
Shi H, Guo J, Duff DJ, Rahmatpanah F, Chitima-Matsiga R, Al-Kuhlani M, Taylor KH, Sjahputera O, Andreski M, Wooldridge JE, et al: Discovery of novel epigenetic markers in non-Hodgkin's lymphoma. Carcinogenesis. 2007, 28: 60-70. 10.1093/carcin/bgl092.
Article
CAS
PubMed
Google Scholar
Taylor KH, Kramer RS, Davis JW, Guo J, Duff DJ, Xu D, Caldwell CW, Shi H: Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing. Cancer Res. 2007, 67: 8511-8518. 10.1158/0008-5472.CAN-07-1016.
Article
CAS
PubMed
Google Scholar
Martin-Subero JI, Kreuz M, Bibikova M, Bentink S, Ammerpohl O, Wickham-Garcia E, Rosolowski M, Richter J, Lopez-Serra L, Ballestar E, et al: New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood. 2009, 113: 2488-2497. 10.1182/blood-2008-04-152900.
Article
CAS
PubMed
Google Scholar
Sanchez-Aguilera A, Delgado J, Camacho FI, Sanchez-Beato M, Sanchez L, Montalban C, Fresno MF, Martin C, Piris MA, Garcia JF: Silencing of the p18INK4c gene by promoter hypermethylation in Reed-Sternberg cells in Hodgkin lymphomas. Blood. 2004, 103: 2351-2357. 10.1182/blood-2003-07-2356.
Article
CAS
PubMed
Google Scholar
Amara K, Trimeche M, Ziadi S, Laatiri A, Hachana M, Korbi S: Prognostic significance of aberrant promoter hypermethylation of CpG islands in patients with diffuse large B-cell lymphomas. Ann Oncol. 2008, 19: 1774-1786. 10.1093/annonc/mdn374.
Article
CAS
PubMed
Google Scholar
Esteller M, Gaidano G, Goodman SN, Zagonel V, Capello D, Botto B, Rossi D, Gloghini A, Vitolo U, Carbone A, et al: Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma. J Natl Cancer Inst. 2002, 94: 26-32.
Article
CAS
PubMed
Google Scholar
Gallatin WM, Weissman IL, Butcher EC: A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature. 1983, 304: 30-34. 10.1038/304030a0.
Article
CAS
PubMed
Google Scholar
Verkaik NS, Trapman J, Romijn JC, van der Kwast TH, van Steenbrugge GJ: Down-regulation of CD44 expression in human prostatic carcinoma cell lines is correlated with DNA hypermethylation. Int J Cancer. 1999, 80: 439-443. 10.1002/(SICI)1097-0215(19990129)80:3<439::AID-IJC17>3.0.CO;2-V.
Article
CAS
PubMed
Google Scholar
Lou W, Krill D, Dhir R, Becich MJ, Dong JT, Frierson HF, Isaacs WB, Isaacs JT, Gao AC: Methylation of the CD44 metastasis suppressor gene in human prostate cancer. Cancer Res. 1999, 59: 2329-2331.
CAS
PubMed
Google Scholar
Hoebeeck J, Michels E, Pattyn F, Combaret V, Vermeulen J, Yigit N, Hoyoux C, Laureys G, De PA, Speleman F, et al: Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. Cancer Lett. 2009, 273: 336-346. 10.1016/j.canlet.2008.08.019.
Article
CAS
PubMed
Google Scholar
Hu XT, Chen YW, Liang AC, Au WY, Wong KY, Wan TS, Wong ML, Shen L, Chan KK, Guo T, et al: CD44 activation in mature B-cell malignancies by a novel recurrent IGH translocation. Blood. 2010, 115: 2458-2461. 10.1182/blood-2009-09-238782.
Article
CAS
PubMed
Google Scholar
Drexler HG: Guide to Leukemia-Lymphoma Cell Lines. 2010, Braunschweig, 2
Google Scholar
Nygren AO, Ameziane N, Duarte HM, Vijzelaar RN, Waisfisz Q, Hess CJ, Schouten JP, Errami A: Methylation-specific MLPA (MS-MLPA): simultaneous detection of CpG methylation and copy number changes of up to 40 sequences. Nucleic Acids Res. 2005, 33: e128-10.1093/nar/gni127.
Article
PubMed
PubMed Central
Google Scholar
Shtivelman E, Bishop JM: Expression of CD44 is repressed in neuroblastoma cells. Mol Cell Biol. 1991, 11: 5446-5453.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bock C, Reither S, Mikeska T, Paulsen M, Walter J, Lengauer T: BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics. 2005, 21: 4067-4068. 10.1093/bioinformatics/bti652.
Article
CAS
PubMed
Google Scholar
Smiraglia DJ, Rush LJ, Fruhwald MC, Dai Z, Held WA, Costello JF, Lang JC, Eng C, Li B, Wright FA, et al: Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies. Hum Mol Genet. 2001, 10: 1413-1419. 10.1093/hmg/10.13.1413.
Article
CAS
PubMed
Google Scholar
Ueki T, Walter KM, Skinner H, Jaffee E, Hruban RH, Goggins M: Aberrant CpG island methylation in cancer cell lines arises in the primary cancers from which they were derived. Oncogene. 2002, 21: 2114-2117. 10.1038/sj.onc.1205275.
Article
CAS
PubMed
Google Scholar
Katzenellenbogen RA, Baylin SB, Herman JG: Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies. Blood. 1999, 93: 4347-4353.
CAS
PubMed
Google Scholar
Rossi D, Capello D, Gloghini A, Franceschetti S, Paulli M, Bhatia K, Saglio G, Vitolo U, Pileri SA, Esteller M, et al: Aberrant promoter methylation of multiple genes throughout the clinico-pathologic spectrum of B-cell neoplasia. Haematologica. 2004, 89: 154-164.
CAS
PubMed
Google Scholar
Wong IH, Chan J, Wong J, Tam PK: Ubiquitous aberrant RASSF1A promoter methylation in childhood neoplasia. Clin Cancer Res. 2004, 10: 994-1002. 10.1158/1078-0432.CCR-0378-3.
Article
CAS
PubMed
Google Scholar
Murray PG, Qiu GH, Fu L, Waites ER, Srivastava G, Heys D, Agathanggelou A, Latif F, Grundy RG, Mann JR, et al: Frequent epigenetic inactivation of the RASSF1A tumor suppressor gene in Hodgkin's lymphoma. Oncogene. 2004, 23: 1326-1331. 10.1038/sj.onc.1207313.
Article
CAS
PubMed
Google Scholar
Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, Ritz J, Shaw S, Silverstein R, Springer T, et al: Leucocyte typing V; white cell differentiation antigens. 1995, New York: Oxford University Press
Google Scholar
Shaffer AL, Yu X, He Y, Boldrick J, Chan EP, Staudt LM: BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity. 2000, 13: 199-212. 10.1016/S1074-7613(00)00020-0.
Article
CAS
PubMed
Google Scholar
Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, et al: Growth-inhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008, 134: 62-73. 10.1016/j.cell.2008.06.006.
Article
CAS
PubMed
PubMed Central
Google Scholar
Huang Q, Gumireddy K, Schrier M, le SC, Nagel R, Nair S, Egan DA, Li A, Huang G, Klein-Szanto AJ, et al: The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis. Nat Cell Biol. 2008, 10: 202-210. 10.1038/ncb1681.
Article
CAS
PubMed
Google Scholar
Herrlich P, Morrison H, Sleeman J, Orian-Rousseau V, Konig H, Weg-Remers S, Ponta H: CD44 acts both as a growth-and invasiveness-promoting molecule and as a tumor-suppressing cofactor. Ann N Y Acad Sci. 2000, 910: 106-118. 10.1111/j.1749-6632.2000.tb06704.x.
Article
CAS
PubMed
Google Scholar
Abecassis I, Maes J, Carrier JL, Hillion J, Goodhardt M, Medjber K, Wany L, Lanotte M, Karniguian A: Re-expression of DNA methylation-silenced CD44 gene in a resistant NB4 cell line: rescue of CD44-dependent cell death by cAMP. Leukemia. 2008, 22: 511-520. 10.1038/sj.leu.2405071.
Article
CAS
PubMed
Google Scholar
Haynes BF, Telen MJ, Hale LP, Denning SM: CD44--a molecule involved in leukocyte adherence and T-cell activation. Immunol Today. 1989, 10: 423-428. 10.1016/0167-5699(89)90040-6.
Article
CAS
PubMed
Google Scholar
Terpe HJ, Koopmann R, Imhof BA, Gunthert U: Expression of integrins and CD44 isoforms in non-Hodgkin's lymphomas: CD44 variant isoforms are preferentially expressed in high-grade malignant lymphomas. J Pathol. 1994, 174: 89-100. 10.1002/path.1711740205.
Article
CAS
PubMed
Google Scholar
Stauder R, Eisterer W, Thaler J, Gunthert U: CD44 variant isoforms in non-Hodgkin's lymphoma: a new independent prognostic factor. Blood. 1995, 85: 2885-2899.
CAS
PubMed
Google Scholar
Lewinsohn DM, Nagler A, Ginzton N, Greenberg P, Butcher EC: Hematopoietic progenitor cell expression of the H-CAM (CD44) homing-associated adhesion molecule. Blood. 1990, 75: 589-595.
CAS
PubMed
Google Scholar
Aguilera NS, Chu WS, Andriko JA, Abbondanzo SL: Expression of CD44 (HCAM) in small lymphocytic and mantle cell lymphoma. Hum Pathol. 1998, 29: 1134-1139. 10.1016/S0046-8177(98)90426-9.
Article
CAS
PubMed
Google Scholar
Fujiwara K, Yoshino T, Miyake K, Ohara N, Akagi T: Expression of a lymphocyte adhesion molecule (CD44) in malignant lymphomas: relevance to primary site, histological subtype and clinical stage. Acta Med Okayama. 1993, 47: 215-222.
CAS
PubMed
Google Scholar
Liang X, Golitz LE, Smoller BR, Meech SJ, Odom LF, Williams SA, Ryder JW: Association of expression of CD44v6 with systemic anaplastic large cell lymphoma: comparison with primary cutaneous anaplastic large cell lymphoma. Am J Clin Pathol. 2002, 117: 276-282.
Article
CAS
PubMed
Google Scholar
Tzankov A, Pehrs AC, Zimpfer A, Ascani S, Lugli A, Pileri S, Dirnhofer S: Prognostic significance of CD44 expression in diffuse large B cell lymphoma of activated and germinal centre B cell-like types: a tissue microarray analysis of 90 cases. J Clin Pathol. 2003, 56: 747-752. 10.1136/jcp.56.10.747.
Article
CAS
PubMed
PubMed Central
Google Scholar
Attarbaschi A, Mann G, Schumich A, Konig M, Pickl WF, Haas OA, Gadner H, Dworzak MN: CD44 deficiency is a consistent finding in childhood Burkitt's lymphoma and leukemia. Leukemia. 2007, 21: 1110-1113.
CAS
PubMed
Google Scholar
Beham-Schmid C, Heider KH, Hoefler G, Zatloukal K: Expression of CD44 splice variant v10 in Hodgkin's disease is associated with aggressive behaviour and high risk of relapse. J Pathol. 1998, 186: 383-389. 10.1002/(SICI)1096-9896(199812)186:4<383::AID-PATH202>3.0.CO;2-A.
Article
CAS
PubMed
Google Scholar
Bendall LJ, Bradstock KF, Gottlieb DJ: Expression of CD44 variant exons in acute myeloid leukemia is more common and more complex than that observed in normal blood, bone marrow or CD34+ cells. Leukemia. 2000, 14: 1239-1246. 10.1038/sj.leu.2401830.
Article
CAS
PubMed
Google Scholar
Naor D, Nedvetzki S, Golan I, Melnik L, Faitelson Y: CD44 in cancer. Crit Rev Clin Lab Sci. 2002, 39: 527-579. 10.1080/10408360290795574.
Article
CAS
PubMed
Google Scholar
Charrad RS, Gadhoum Z, Qi J, Glachant A, Allouche M, Jasmin C, Chomienne C, Smadja-Joffe F: Effects of anti-CD44 monoclonal antibodies on differentiation and apoptosis of human myeloid leukemia cell lines. Blood. 2002, 99: 290-299. 10.1182/blood.V99.1.290.
Article
CAS
PubMed
Google Scholar
Maquarre E, Artus C, Gadhoum Z, Jasmin C, Smadja-Joffe F, Robert-Lezenes J: CD44 ligation induces apoptosis via caspase-and serine protease-dependent pathways in acute promyelocytic leukemia cells. Leukemia. 2005, 19: 2296-2303. 10.1038/sj.leu.2403944.
Article
CAS
PubMed
Google Scholar
Platt VM, Szoka FC: Anticancer therapeutics: targeting macromolecules and nanocarriers to hyaluronan or CD44, a hyaluronan receptor. Mol Pharm. 2008, 5: 474-486. 10.1021/mp800024g.
Article
CAS
PubMed
PubMed Central
Google Scholar
Picker LJ, Medeiros LJ, Weiss LM, Warnke RA, Butcher EC: Expression of lymphocyte homing receptor antigen in non-Hodgkin's lymphoma. Am J Pathol. 1988, 130: 496-504.
CAS
PubMed
PubMed Central
Google Scholar
Pals ST, Horst E, Ossekoppele GJ, Figdor CG, Scheper RJ, Meijer CJ: Expression of lymphocyte homing receptor as a mechanism of dissemination in non-Hodgkin's lymphoma. Blood. 1989, 73: 885-888.
CAS
PubMed
Google Scholar