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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. Surgery is an important therapeutic option for brain metastases. Currently, postoperative stereotactic radiosurgery (SRT) leads to 6-month and 1-year local control estimated at 70 and 62% respectively. However...

    Authors: Angeline Ginzac, Guillaume Dupic, Lucie Brun, Ioana Molnar, Mélanie Casile, Xavier Durando, Pierre Verrelle, Jean-Jacques Lemaire, Toufic Khalil and Julian Biau
    Citation: BMC Cancer 2021 21:864
  2. Non-gestational choriocarcinoma (NGC) is a rare subtype of malignant germ cell tumour and there is no consensus on its treatment. The lack of suitable preclinical models for NGC is a challenge in drug discover...

    Authors: Yukari Oda, Kaoru Niimi, Kosuke Yoshida, Satoshi Tamauchi, Akira Yokoi, Yuko Yasui, Yuki Nishiko, Mayu Shibata, Yusuke Shimizu, Masato Yoshihara, Yoshiki Ikeda, Nobuhisa Yoshikawa, Kimihiro Nishino, Eiko Yamamoto and Hiroaki Kajiyama
    Citation: BMC Cancer 2023 23:1103
  3. Pucotenlimab is a novel recombinant humanized anti-PD-1 (Programmed death-1) monoclonal antibody, which belongs to the human IgG4/kappa subtype, and can selectively block the binding of PD-1 with its ligands P...

    Authors: Chuanliang Cui, Yu Chen, Zhiguo Luo, Zhengyun Zou, Yu Jiang, Hongming Pan, Qingxia Fan, Jianfu Zhao, Qing Xu, Renbing Jiang, Xuan Wang, Taiyang Ma, Zhen Guo, Lu Si, Zhihong Chi, Xinan Sheng…
    Citation: BMC Cancer 2023 23:121
  4. Prostaglandin (PG) E2 plays a critical role in colorectal cancer (CRC) progression, including epithelial-mesenchymal transition (EMT). Activity of the rate-limiting enzyme for PGE2 catabolism (15-hydroxyprostagla...

    Authors: Alastair L Young, Claire R Chalmers, Gillian Hawcroft, Sarah L Perry, Darren Treanor, Giles J Toogood, Pamela F Jones and Mark A Hull
    Citation: BMC Cancer 2013 13:92
  5. The VELOUR study demonstrated a survival benefit for FOLFIRI + aflibercept versus FOLFIRI + placebo in metastatic colorectal cancer (mCRC) patients who progressed on oxaliplatin-based chemotherapy. Continued d...

    Authors: Ian Chau, Florence Joulain, Sheikh Usman Iqbal and John Bridgewater
    Citation: BMC Cancer 2014 14:605
  6. Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in China and is an exceptionally drug-resistant tumor with a 5-year survival rate less than 15%. Cisplatin is the most commonly ...

    Authors: Xinfang Yu, Wei Li, Zhenkun Xia, Li Xie, Xiaolong Ma, Qi Liang, Lijun Liu, Jian Wang, Xinmin Zhou, Yifeng Yang and Haidan Liu
    Citation: BMC Cancer 2017 17:449
  7. Intrahepatic cholangiocarcinoma (CCA) is amongst the most common primary liver tumors worldwide. CCA carries a bad prognosis prompting research to establish new treatment modalities other than surgery and the ...

    Authors: Charbel Elias, Youssef H. Zeidan, Youssef Bouferraa, Deborah Mukherji, Sally Temraz, Maya Charafeddine, Monita Al Darazi and Ali Shamseddine
    Citation: BMC Cancer 2022 22:1296
  8. Carcinoid heart disease is a rare disease which develops in patients with functional neuroendocrine tumors in an advanced tumor state. Patients diagnosed with carcinoid heart disease have a poor longtime progn...

    Authors: Eva Grundmann, Alessandra Curioni-Fontecedro, Emanuel Christ and Alexander R. Siebenhüner
    Citation: BMC Cancer 2023 23:338
  9. Ras is a control switch of ERK1/2 pathway, and hyperactivation of Ras-ERK1/2 signaling appears frequently in human cancers. However, the molecular regulation following by Ras-ERK1/2 activation is still unclear...

    Authors: Peng Tian, Yanfei Zhu, Chao Zhang, Xinyu Guo, Peng Zhang and Huanzhou Xue
    Citation: BMC Cancer 2018 18:1286

    The Retraction Note to this article has been published in BMC Cancer 2021 21:594

  10. The information surgeons impart to patients and information patients want about surgery for cancer is important but rarely examined. This study explored information provided by surgeons and patient preferences...

    Authors: Angus G. K. McNair, F MacKichan, J. L. Donovan, S. T. Brookes, K. N. L. Avery, S. M. Griffin, T. Crosby and J. M. Blazeby
    Citation: BMC Cancer 2016 16:258
  11. The differential diagnosis of follicular thyroid carcinoma (FTC) and follicular adenoma (FA) before surgery is a clinical challenge. Many efforts have been made but most focusing on tumor cells, while the role...

    Authors: Feng-Jiao Huang, Xiao-Yi Zhou, Lei Ye, Xiao-Chun Fei, Shu Wang, Weiqing Wang and Guang Ning
    Citation: BMC Cancer 2016 16:98
  12. Circulating long non-coding RNAs (lncRNAs) have been demonstrated to serve as diagnostic or prognosis biomarkers for various disease. We aimed to elucidate the diagnostic efficacy of serum lncRNA SCARNA10 for ...

    Authors: Yawei Han, Wenna Jiang, Yu Wang, Meng Zhao, Yueguo Li and Li Ren
    Citation: BMC Cancer 2022 22:431
  13. The aim of our study was to assess the feasibility and oncologic outcomes in patients treated with spinal (SI) or craniospinal irradiation (CSI) in patients with leptomeningeal metastases (LM) and to suggest a...

    Authors: Michal Devecka, Marciana Nona Duma, Jan J. Wilkens, Severin Kampfer, Kai Joachim Borm, Stefan Münch, Christoph Straube and Stephanie E. Combs
    Citation: BMC Cancer 2020 20:501
  14. To compare the clinical characteristics and prognoses of patients with isolated regional lymph node recurrent nasopharyngeal carcinoma (irrNPC) who underwent surgery or re-irradiation treatment.

    Authors: Yuebing Chen, Yiping Huang, Xiaoqiang Chen, Zhiwei Chen, Xiane Peng, Shaojun Lin, Cheng Lin and Jingfeng Zong
    Citation: BMC Cancer 2024 24:483
  15. Well-differentiated (WD) neuroendocrine tumors (NETs) are a group of rare neoplasms with limited therapeutic options. Cabozantinib is an inhibitor of multiple tyrosine kinases with a pivotal role in NET pathog...

    Authors: Francesca Corti, Maria Pia Brizzi, Vito Amoroso, Dario Giuffrida, Francesco Panzuto, Davide Campana, Natalie Prinzi, Massimo Milione, Tommaso Cascella, Carlo Spreafico, Giovanni Randon, Simone Oldani, Rita Leporati, Giulia Scotto, Iolanda Pulice, Benedetta Lombardi Stocchetti…
    Citation: BMC Cancer 2023 23:908
  16. The new modalities for treating patients with non-muscle invasive bladder cancer (NMIBC) for whom BCG (Bacillus Calmette-Guerin) has failed or is contraindicated are recently increasing due to the development of ...

    Authors: Patrick Vianna Garcia, Fábio Rodrigues Ferreira Seiva, Amanda Pocol Carniato, Wilson de Mello Júnior, Nelson Duran, Alda Maria Macedo, Alexandre Gabarra de Oliveira, Rok Romih, Iseu da Silva Nunes, Odilon da Silva Nunes and Wagner José Fávaro
    Citation: BMC Cancer 2016 16:422
  17. Vascular endothelial growth factor (VEGF) plays a role in the tumor microenvironment. Sorafenib, which inhibits the VEGF pathway, has an immune-modulation function but lacks substantial clinical data. This stu...

    Authors: San-Chi Chen, Yi-Hsiang Huang, Ming-Huang Chen, Yi-Ping Hung, Rheun-Chuan Lee, Yu-Yun Shao and Yee Chao
    Citation: BMC Cancer 2022 22:55
  18. Drug resistance is still one of the key causes of death in epithelial ovarian carcinoma (EOC) patients, however there are very few strategies to reverse chemoresistance. Here we try to clarify whether and how ...

    Authors: Xiao Li, Qianqian Pan, Xiaoyun Wan, Yuyan Mao, Weiguo Lu, Xing Xie and Xiaodong Cheng
    Citation: BMC Cancer 2015 15:509
  19. The failure rate after neoadjuvant chemoradiotherapy followed by surgery is approximately 34.6%–48% for resectable esophageal carcinoma. Pathologic complete response after neoadjuvant chemoradiotherapy is an i...

    Authors: Jinsong Yang, Ai Huang, Kunyu Yang and Ke Jiang
    Citation: BMC Cancer 2023 23:249
  20. Realistic pre-treatment expectations are important and have been associated with post-treatment health related quality of life (HRQOL). Patient expectations are greatly influenced by physicians, as they are th...

    Authors: Anne L. Versteeg, Roxanne Gal, Raphaele Charest-Morin, Jorrit-Jan Verlaan, Hester Wessels, Charles G. Fisher and Helena M. Verkooijen
    Citation: BMC Cancer 2021 21:1263
  21. Magnetic resonance imaging (MRI) has improved capacity to visualize tumor and soft tissue involvement in head and neck cancers. Using advanced MRI, we can interrogate cell density using diffusion weighted imag...

    Authors: Sweet Ping Ng, Houda Bahig, Jihong Wang, Carlos E. Cardenas, Anthony Lucci, Carolyn S. Hall, Salyna Meas, Vanessa N. Sarli, Ying Yuan, Diana L. Urbauer, Yao Ding, Shane Ikner, Vi Dinh, Baher A. Elgohari, Jason M. Johnson, Heath D. Skinner…
    Citation: BMC Cancer 2018 18:903
  22. Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease that lack of effective therapeutic drugs. K-001 is an oral antitumor drug made from active ingredients of marine microorganisms. The current study ai...

    Authors: Jiujie Cui, Haiyan Yang, Jue Liu, Donghui Chen, Jiong Hu, Haiyan Zhang, Yu Wang, Ting Han, Tiebo Mao, Feng Jiao, Ewelina Biskup, Yaotian Pan, Min Liu and Liwei Wang
    Citation: BMC Cancer 2021 21:672
  23. Standard chemotherapy in unresectable biliary tract carcinoma (BTC) patients is based on gemcitabine combined with platinum derivatives. However, primary or acquired resistance is inevitable and no second-line...

    Authors: Caterina Peraldo-Neia, Giuliana Cavalloni, Marco Soster, Loretta Gammaitoni, Serena Marchiò, Francesco Sassi, Livio Trusolino, Andrea Bertotti, Enzo Medico, Lorenzo Capussotti, Massimo Aglietta and Francesco Leone
    Citation: BMC Cancer 2014 14:918
  24. More knowledge about genetic and molecular features of cholangiocarcinoma is needed to develop effective therapeutic strategies. We investigated the clinical and pathological significance of ROS1 expression in...

    Authors: Kyung-Hun Lee, Kyoung-Bun Lee, Tae-Yong Kim, Sae-Won Han, Do-Youn Oh, Seock-Ah Im, Tae-You Kim, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Ja-June Jang and Yung-Jue Bang
    Citation: BMC Cancer 2015 15:721
  25. Tumor-associated macrophages (TAMs) are implicated in the growth, invasion and metastasis of various solid tumors. However, the phenotype of TAMs in premalignant lesions of solid tumors has not been clarified....

    Authors: Kazumasa Mori, Shigeki Haraguchi, Miki Hiori, Jun Shimada and Yoshihiro Ohmori
    Citation: BMC Cancer 2015 15:573
  26. Urokinase plasminogen activator (uPA) receptor (uPAR) is up-regulated at the invasive tumour front of human oral squamous cell carcinoma (OSCC), indicating a role for uPAR in tumour progression. We previously ...

    Authors: Synnove Norvoll Magnussen, Elin Hadler-Olsen, Daniela Elena Costea, Eli Berg, Cristiane Cavalcanti Jacobsen, Bente Mortensen, Tuula Salo, Inigo Martinez-Zubiaurre, Jan-Olof Winberg, Lars Uhlin-Hansen and Gunbjorg Svineng
    Citation: BMC Cancer 2017 17:350
  27. Soft tissue sarcomas (STS), have significant inter- and intra-tumoral heterogeneity, with poor response to standard neoadjuvant radiotherapy (RT). Achieving a favorable pathologic response (FPR ≥ 95%) from RT ...

    Authors: Arash O. Naghavi, J. M. Bryant, Youngchul Kim, Joseph Weygand, Gage Redler, Austin J. Sim, Justin Miller, Kaitlyn Coucoules, Lauren Taylor Michael, Warren E. Gloria, George Yang, Stephen A. Rosenberg, Kamran Ahmed, Marilyn M. Bui, Evita B. Henderson-Jackson, Andrew Lee…
    Citation: BMC Cancer 2024 24:437
  28. To assess the effects of Epstein–Barr virus (EBV) and human papillomavirus (HPV) infection on the tumor microenvironment, we examined the relationship between viral infection status, macrophage migration inhib...

    Authors: Guofei Feng, Yifei Xu, Ning Ma, Kaoru Midorikawa, Shinji Oikawa, Hatasu Kobayashi, Satoshi Nakamura, Hajime Ishinaga, Zhe Zhang, Guangwu Huang, Kazuhiko Takeuchi and Mariko Murata
    Citation: BMC Cancer 2021 21:929
  29. The SWI/SNF complex is an important chromatin remodeler, commonly dysregulated in cancer, with an estimated mutation frequency of 20%. ARID1A is the most frequently mutated subunit gene. Almost nothing is know...

    Authors: Simon Schallenberg, Julian Bork, Ahlem Essakly, Hakan Alakus, Reinhard Buettner, Axel M. Hillmer, Christiane Bruns, Wolfgang Schroeder, Thomas Zander, Heike Loeser, Florian Gebauer and Alexander Quaas
    Citation: BMC Cancer 2020 20:12
  30. CC-chemokine receptor seven (CCR7), a G-protein coupled receptor normally facilitating immune cells lymphatic homing, has recently been identified on several cancer cells in promoting invasion and lymphatic sp...

    Authors: Yu Xia, Li Liu, Ying Xiong, Qi Bai, Jiajun Wang, Wei Xi, Yang Qu, Jiejie Xu and Jianming Guo
    Citation: BMC Cancer 2017 17:70
  31. Metastatic Adrenocortical Carcinoma (ACC) is a rare malignancy with a poor 5-year-survival rate (<15%). A surgical approach is recommended in selected patients if complete resection of distant metastasis can b...

    Authors: Johannes Baur, Tjark-Ole Büntemeyer, Felix Megerle, Timo Deutschbein, Christine Spitzweg, Marcus Quinkler, Peter Nawroth, Matthias Kroiss, Christoph-Thomas Germer, Martin Fassnacht and Ulrich Steger
    Citation: BMC Cancer 2017 17:522
  32. Oral cancer malignancy consists of uncontrolled division of cells primarily in and around the floor of the oral cavity, gingiva, oropharynx, lower lip and base of the tongue. According to GLOBOCAN 2012 report,...

    Authors: Muraleedharan Parvathy, Sreeharshan Sreeja, Rakesh Kumar and Madhavan Radhakrishna Pillai
    Citation: BMC Cancer 2016 16(Suppl 1):293

    This article is part of a Supplement: Volume 16 Supplement 1

  33. Bleomycin, etoposide, and cisplatin (BEP) chemotherapy administered every 3 weeks for 4 cycles remains the standard first line treatment for patients with intermediate- and poor-risk metastatic germ cell tumou...

    Authors: Nicola J. Lawrence, Howard Chan, Guy Toner, Martin R. Stockler, Andrew Martin, Sonia Yip, Nicole Wong, Annie Yeung, Danish Mazhar, Farzana Pashankar, Lindsay Frazier, Ray McDermott, Roderick Walker, Hsiang Tan, Ian D. Davis and Peter Grimison
    Citation: BMC Cancer 2018 18:854
  34. This study aimed to identify the biological functions, expression modes, and possible mechanisms underlying the relationship between metastatic human hepatocellular carcinoma (HCC) and MicroRNA-188-5p (miR-188...

    Authors: Yan-hui Wu, Bin Yu, Jiang-min Zhou, Xue-han Shen, Wei-xun Chen, Xi Ai, Chao Leng, Bin-yong Liang and Ya-jie Shao
    Citation: BMC Cancer 2023 23:511
  35. Recently, a gene expression algorithm, TNBCtype, was developed that can divide triple-negative breast cancer (TNBC) into molecularly-defined subtypes. The algorithm has potential to provide predictive value fo...

    Authors: Brian Z. Ring, David R. Hout, Stephan W. Morris, Kasey Lawrence, Brock L. Schweitzer, Daniel B. Bailey, Brian D. Lehmann, Jennifer A. Pietenpol and Robert S. Seitz
    Citation: BMC Cancer 2016 16:143

    The Erratum to this article has been published in BMC Cancer 2016 16:275

  36. Overexpression of heterogeneous nuclear ribonucleoprotein K (hnRNP K), a DNA/RNA binding protein, is associated with metastasis in nasopharyngeal carcinoma (NPC). However, the mechanisms underlying hnRNP K-med...

    Authors: I-Che Chung, Lih-Chyang Chen, An-Ko Chung, Mei Chao, Hsin-Yi Huang, Chuen Hsueh, Ngan-Ming Tsang, Kai-Ping Chang, Ying Liang, Hsin-Pai Li and Yu-Sun Chang
    Citation: BMC Cancer 2014 14:348
  37. Gemcitabine plus platinum as the first-line chemotherapy for cholangiocarcinoma (CCA) has limited efficacy. The aim of this study was to evaluate the effectiveness of modified FOLFIRINOX (mFOLFIRINOX) compared...

    Authors: Lu Zou, Xuechuan Li, Xiangsong Wu, Jiujie Cui, Xuya Cui, Xiaoling Song, Tai Ren, Xusheng Han, Yidi Zhu, Huaifeng Li, Wenguang Wu, Xu’an Wang, Wei Gong, Liwei Wang, Maolan Li, Wan Yee Lau…
    Citation: BMC Cancer 2021 21:818
  38. Adult T-cell Leukemia (ATL) is a disease with no known cure. The disease manifests itself as an aggressive proliferation of CD4+ cells with the human T-cell Lymphotropic virus type 1 (HTLV-1). The leukemogenesis ...

    Authors: Steve Harakeh, Rania Azar, Esam Azhar, Ghazi A Damanhouri, Mourad Assidi, Muhammad Abu-Elmagd, Mohammed H Alqahtani, Taha Kumosani, Aleksandra Niedzwiecki, Mathias Rath, Ahmed Al-Hejin, Elie Barbour and Mona Diab-Assaf
    Citation: BMC Cancer 2015 15(Suppl 1):S2

    This article is part of a Supplement: Volume 15 Supplement 1

  39. Radiomics may provide more objective and accurate predictions for extrahepatic cholangiocarcinoma (ECC). In this study, we developed radiomics models based on magnetic resonance imaging (MRI) and machine learn...

    Authors: Yong Tang, Chun Mei Yang, Song Su, Wei Jia Wang, Li Ping Fan and Jian Shu
    Citation: BMC Cancer 2021 21:1268
  40. Breast cancer is the most common cancer in women in the U.S. and Western Europe. Amplification of the her-2/neu gene occurs in approximately 25% of invasive ductal carcinomas of the breast. The first HER-2/neu...

    Authors: Gustavo A Viani, Sergio L Afonso, Eduardo J Stefano, Ligia I De Fendi and Francisco V Soares
    Citation: BMC Cancer 2007 7:153
  41. Chemoradiotherapy (CRT) and bio-radiotherapy (BRT) are recognized as standard therapies for head and neck cancer (HNC). Aspiration pneumonia after CRT or BRT is a common late adverse event. Our aim in this stu...

    Authors: Sadayuki Kawai, Tomoya Yokota, Yusuke Onozawa, Satoshi Hamauchi, Akira Fukutomi, Hirofumi Ogawa, Tsuyoshi Onoe, Tetsuro Onitsuka, Takashi Yurikusa, Akiko Todaka, Takahiro Tsushima, Yukio Yoshida, Yosuke Kito, Keita Mori and Hirofumi Yasui
    Citation: BMC Cancer 2017 17:59
  42. The prognosis of ductal carcinoma in situ (DCIS) is reportedly well. Extremely rare patients with DCIS develop distant breast cancer metastasis without locoregional or contralateral recurrence. This is the fir...

    Authors: Qiuting You, Yichao Fang, Chenchen Li, Yujie Tan, Jianli Zhao, Cui Tan, Ying Wang, Herui Yao and Fengxi Su
    Citation: BMC Cancer 2019 19:844
  43. Extranodal extension (ENE) is a poor prognostic factor for oral squamous cell carcinoma (OSCC). Identifying ENE by clinical and/or radiological examination is difficult, thereby leading to unnecessary neck dis...

    Authors: Yuri Noda, Mitsuaki Ishida, Yasuhiro Ueno, Takuo Fujisawa, Hiroshi Iwai and Koji Tsuta
    Citation: BMC Cancer 2022 22:402
  44. Metastasis-directed therapy (MDT) significantly delays the initiation of palliative androgen deprivation therapy (pADT) in patients with oligorecurrent prostate cancer (PCa) with a positive impact on patient’s...

    Authors: Kato Rans, Berghen Charlien, Ameye Filip, De Hertogh Olivier, den Hartog Julie, Draulans Céderic, Dumez Herlinde, Engels Benedikt, Goffin Karolien, Laenen Annouschka, Liefhooghe Nick, Poels Kenneth, Salembier Carl, Slabbaert Koen, Vandendriessche Hans, Vanneste Ben…
    Citation: BMC Cancer 2022 22:1294
  45. Portal hypertension (PHT) has been proven to be closely related to the development of hepatocellular carcinoma (HCC). Whether PHT before liver transplantation (LT) will affect the recurrence of HCC is not clear.

    Authors: Guo Wei, Yong Zhao, Shifeng Feng, Jingsheng Yuan, Gang Xu, Tao Lv, Jian Yang, Lingxiang Kong and Jiayin Yang
    Citation: BMC Cancer 2024 24:558
  46. Perturbed genotypes in cancer can now be identified by whole genome sequencing of large number of diverse tumor samples, and observed gene mutations can be used for prognosis and classification of cancer subty...

    Authors: Sarah Daakour, Leon Juvenal Hajingabo, Despoina Kerselidou, Aurelie Devresse, Richard Kettmann, Nicolas Simonis, Franck Dequiedt and Jean-Claude Twizere
    Citation: BMC Cancer 2016 16:335
  47. Brain metastases are the most common intracranial tumours. Variation exists in the use of stereotactic radiosurgery for patients with 10 or more brain metastases. Concerns include an increasing number of brain...

    Authors: Hamoun Rozati, Jiarong Chen and Matt Williams
    Citation: BMC Cancer 2023 23:1004

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