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Retraction Note: Ras-ERK1/2 signaling contributes to the development of colorectal cancer via regulating H3K9ac

The Original Article was published on 22 December 2018

Retraction Note: BMC Cancer 18, 1286 (2018)

The Editor in Chief retracted this article because of significant concerns regarding a number of Figures presented in this work, which question the integrity of the data. Specifically, a number of images appear to be the same and rotated between Fig. 2C, 2D and 4D in this article, and Fig. 2 and 3 in an article published earlier by unrelated authors ([1], now retracted). In addition, it appears that one image was re-used between Fig. 2D and 4D within this article.

The Editor-in-Chief therefore no longer has confidence in the integrity of the data in this article.

The authors have not responded to any correspondence from the editor or publisher about this retraction.


  1. Huang, S, Jin, A. ZIC2 promotes viability and invasion of human osteosarcoma cells by suppressing SHIP2 expression and activating PI3K/AKT pathways. J Cell Biochem. 2018;119:2248–57.

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Correspondence to Huanzhou Xue.

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Tian, P., Zhu, Y., Zhang, C. et al. Retraction Note: Ras-ERK1/2 signaling contributes to the development of colorectal cancer via regulating H3K9ac. BMC Cancer 21, 594 (2021).

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