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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 57 of 79

  2. The ML18174 study, which showed benefits of bevacizumab (BEV) continuation beyond progression (BBP) for metastatic colorectal cancer (mCRC), excluded patients with first-line progression-free survival (PFS) sh...

    Authors: Shun Yamamoto, Kengo Nagashima, Takeshi Kawakami, Seiichiro Mitani, Masato Komoda, Yasushi Tsuji, Naoki Izawa, Kentaro Kawakami, Yoshiyuki Yamamoto, Akitaka Makiyama, Kentaro Yamazaki, Toshiki Masuishi, Taito Esaki, Takako Eguchi Nakajima, Hiroyuki Okuda, Toshikazu Moriwaki…
    Citation: BMC Cancer 2021 21:1159
    Content type: Research article Published on:

  3. Personalized therapy for bone metastases should consider the patients’ remaining lifespan. Estimation of survival can be facilitated with scoring tools. A new tool was developed, specifically designed to estim...

    Authors: Dirk Rades, Rapha Haus, Steven E. Schild and Stefan Janssen
    Citation: BMC Cancer 2019 19:1156
    Content type: Research article Published on:

  4. Long non-coding RNA (lncRNA) H19 has gained significant recognition as a pivotal contributor to the initiation and advancement of gynecologic cancers, encompassing ovarian, endometrial, cervical, and breast ca...

    Authors: Majid Ghasemian, Mojtaba Zehtabi, Mahrokh Abouali Gale Dari, Fatemeh Khojasteh Pour, Ghasem Azizi Tabesh, Farideh Moramezi, Razieh Mohammad Jafari, Mojgan Barati, Shahab Uddin and Maryam Farzaneh
    Citation: BMC Cancer 2024 24:4
    Content type: Review Published on:

  5. Globally, the incidence and mortality rates of gastric cancer are high, and its poor prognosis is closely related to tumor recurrence and metastasis. Therefore, the molecular mechanisms associated with the mig...

    Authors: Yaoyue Qi, Jing Lv, Shihai Liu, Libin Sun, Yixuan Wang, Hui Li, Weiwei Qi and Wensheng Qiu
    Citation: BMC Cancer 2019 19:630
    Content type: Research article Published on:

  6. After two studies reporting response rates higher than 70% in HER2-positive metastatic breast cancer with weekly trastuzumab and vinorelbine, we planned a phase 2 study to test activity of the same combination...

    Authors: Ermelinda De Maio, Carmen Pacilio, Adriano Gravina, Alessandro Morabito, Francesca Di Rella, Vincenzo Labonia, Gabriella Landi, Francesco Nuzzo, Emanuela Rossi, Pasqualina Silvestro, Gerardo Botti, Maurizio Di Bonito, Maria Pia Curcio, Franca Formichelli, Franca La Vecchia, Maria Staiano…
    Citation: BMC Cancer 2007 7:50
    Content type: Research article Published on:

  7. Organ site-specific metastasis is an ominous feature for most poor-prognostic hepatocellular carcinoma (HCC) patients. Cancer cell lines and animal models are indispensable for investigating the molecular mech...

    Authors: Jinliang Wan, Duo Wen, Lili Dong, Jun Tang, Dongli Liu, Yang Liu, Zhonghua Tao, Dongmei Gao, Huichuan Sun, Ya Cao, Jia Fan and Weizhong Wu
    Citation: BMC Cancer 2015 15:678
    Content type: Research article Published on:

  8. Brain metastases (BM) represent one of the most frequent complications related to cancer, and their treatment continues to evolve. We have evaluated the activity, toxicity and the impact on Quality of Life (Qo...

    Authors: Raffaele Addeo, Michele Caraglia, Vincenzo Faiola, Elena Capasso, Bruno Vincenzi, Liliana Montella, Rosario Guarrasi, Luigi Caserta and Salvatore Del Prete
    Citation: BMC Cancer 2007 7:18
    Content type: Research article Published on:

  9. This study examined the prognostic significance of microtubule-associated protein light chain 3B (LC3B) expression in oropharyngeal and oral cavity squamous cell carcinoma (SCC). The prognostic significance of...

    Authors: Kenneth Lai, Slade Matthews, James S. Wilmott, Murray C. Killingsworth, Jim L. Yong, Nicole J. Caixeiro, James Wykes, Allan Samakeh, Dion Forstner, Mark Lee, John McGuinness, Navin Niles, Angela Hong, Ardalan Ebrahimi and Cheok Soon Lee
    Citation: BMC Cancer 2018 18:624
    Content type: Research article Published on:

  10. Anaplastic thyroid carcinoma is the most undifferentiated form of thyroid cancer and one of the deadliest of all adult solid malignancies. Here we report the first genomic and transcriptomic profile of anaplas...

    Authors: Katayoon Kasaian, Sam M. Wiseman, Blair A. Walker, Jacqueline E. Schein, Yongjun Zhao, Martin Hirst, Richard A. Moore, Andrew J. Mungall, Marco A. Marra and Steven JM Jones
    Citation: BMC Cancer 2015 15:984
    Content type: Research article Published on:

  11. Colorectal cancer (CRC) is a heterogeneous disease, with subtypes that have different clinical behaviours and subsequent prognoses. There is a growing body of evidence suggesting that right-sided colorectal ca...

    Authors: Tyler Kolisnik, Arielle Kae Sulit, Sebastian Schmeier, Frank Frizelle, Rachel Purcell, Adam Smith and Olin Silander
    Citation: BMC Cancer 2023 23:647
    Content type: Research Published on:

  12. DEK is a transcription factor involved in stabilization of heterochromatin and cruciform structures. It plays an important role in development and progression of different types of cancer. This study aims to a...

    Authors: Javier Martinez-Useros, Maria Rodriguez-Remirez, Aurea Borrero-Palacios, Irene Moreno, Arancha Cebrian, Teresa Gomez del Pulgar, Laura del Puerto-Nevado, Ricardo Vega-Bravo, Alberto Puime-Otin, Nuria Perez, Sandra Zazo, Clara Senin, Maria J Fernandez-Aceñero, Maria S Soengas, Federico Rojo and Jesus Garcia-Foncillas
    Citation: BMC Cancer 2014 14:965
    Content type: Research article Published on:

  13. Androgen deprivation therapy (ADT) in the treatment of prostate cancer may be associated with an increased risk of thromboembolic disease. The aim of our study was to investigate the association of ADT in the ...

    Authors: Kuang-Ming Liao, Yaw-Bin Huang, Chung-Yu Chen and Chen-Chun Kuo
    Citation: BMC Cancer 2019 19:1263
    Content type: Research article Published on:

  14. Histone acetyltransferases (HATs) of the MYST family are associated with a variety of human cancers. However, the relationship between MYST HATs and their clinical significance in kidney renal clear cell carci...

    Authors: Fan Liang, Xiangke Li, Xiaoman Shen, Runlei Yang and Chuan Chen
    Citation: BMC Cancer 2023 23:586
    Content type: Research Published on:

  15. SIRT1 is a member of the mammalian sirtuin family with the ability to deacetylate histone and nonhistone proteins. The correlation between SIRT1 expression and tumor metastasis in several types of cancer has a...

    Authors: Chong Hao, Peng-Xi Zhu, Xue Yang, Zhi-Peng Han, Jing-Hua Jiang, Chen Zong, Xu-Guang Zhang, Wen-Ting Liu, Qiu-Dong Zhao, Ting-Ting Fan, Li Zhang and Li-Xin Wei
    Citation: BMC Cancer 2014 14:978
    Content type: Research article Published on:

  16. We previously identified and characterized a novel 55 kDa nuclear protein, termed nmt55/p54nrb, whose expression was decreased in a subset of human breast tumors. The objective of this study was to determine if t...

    Authors: Matthew Pavao, Yue-Hua Huang, Laurie J Hafer, Robert B Moreland and Abdulmaged M Traish
    Citation: BMC Cancer 2001 1:15
    Content type: Research article Published on:

  19. Serous epithelial ovarian tumors can be subdivided into benign (BOV), low malignant potential (LMP) or borderline and invasive (TOV) tumors. Although the molecular characteristics of serous BOV, LMP and low gr...

    Authors: Véronique Ouellet, Tak Hay Ling, Karine Normandin, Jason Madore, Christian Lussier, Véronique Barrès, Dimcho Bachvarov, Claudine Rancourt, Patricia N Tonin, Diane M Provencher and Anne-Marie Mes-Masson
    Citation: BMC Cancer 2008 8:346
    Content type: Research article Published on:

  20. The gold standard for bladder cancer detection is cystoscopy, which is an invasive procedure that causes discomfort in patients. The currently available non-invasive approaches either show limited sensitivity ...

    Authors: Hao Liu, Wang He, Bo Wang, Kewei Xu, Jinli Han, Junjiong Zheng, Jun Ren, Lin Shao, Shiping Bo, Sijia Lu, Tianxin Lin and Jian Huang
    Citation: BMC Cancer 2018 18:659
    Content type: Research article Published on:

  21. Pancreatic cancer is characterized by a highly immunosuppressive tumor microenvironment and evasion of immune surveillance. Although programmed cell death 1 receptor (PD-1) blockade has achieved certain succes...

    Authors: Guoping Ding, Tao Shen, Chen Yan, Mingjie Zhang, Zhengrong Wu and Liping Cao
    Citation: BMC Cancer 2019 19:1053
    Content type: Research article Published on:

  22. Archival formalin-fixed paraffin-embedded (FFPE) cancer tissue samples are a readily available resource for microRNA (miRNA) biomarker identification. No established standard for reference miRNAs in FFPE tissu...

    Authors: Mogens Karsbøl Boisen, Christian Dehlendorff, Dorte Linnemann, Nicolai Aagaard Schultz, Benny Vittrup Jensen, Estrid Vilma Solyom Høgdall and Julia Sidenius Johansen
    Citation: BMC Cancer 2015 15:1024
    Content type: Research article Published on:

  23. A Disintegrin And Metalloprotease (ADAM) 9 has been implicated in tumour progression of various solid tumours, however, little is known about its role in renal cell carcinoma. We evaluated the expression of ADAM...

    Authors: Florian R Fritzsche, Kirsten Wassermann, Monika Jung, Angelika Tölle, Ilka Kristiansen, Michael Lein, Manfred Johannsen, Manfred Dietel, Klaus Jung and Glen Kristiansen
    Citation: BMC Cancer 2008 8:179
    Content type: Research article Published on:

  24. Carcinoembryonic antigen (CEA) and carbohydrate antigen (CA)19–9 are used in clinical practice as tumor markers to diagnose or monitor colorectal cancer (CRC) patients, However, their specificities and sensiti...

    Authors: Eiji Shinozaki, Kazuhiro Tanabe, Takashi Akiyoshi, Tomohiro Tsuchida, Yuko Miyazaki, Nozomi Kojima, Masahiro Igarashi, Masashi Ueno, Mitsukuni Suenaga, Nobuyuki Mizunuma, Kensei Yamaguchi, Konosuke Nakayama, Sadayo Iijima and Toshiharu Yamaguchi
    Citation: BMC Cancer 2018 18:406
    Content type: Research article Published on:

  25. Dysregulation of microRNA (miRNA) expression is associated with hallmarks of aggressive tumor phenotypes, e.g., enhanced cell growth, proliferation, invasion, and anchorage independent growth in prostate cance...

    Authors: Dominique Z. Jones, M. Lee Schmidt, Suman Suman, Katharine R. Hobbing, Shirish S. Barve, Leila Gobejishvili, Guy Brock, Carolyn M. Klinge, Shesh N. Rai, Jong Park, Geoffrey J. Clark, Rajesh Agarwal and LaCreis R. Kidd
    Citation: BMC Cancer 2018 18:421
    Content type: Research article Published on:

  26. The combination platinum, 5-fluorouracil (5-FU) and cetuximab is the standard first-line regimen of recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC). Due to the toxicity of this treatm...

    Authors: Julien Péron, Valentine Polivka, Sylvie Chabaud, Marc Poupart, Philippe Ceruse, Antoine Ramade, Didier Girodet, Philippe Zrounba and Jérôme Fayette
    Citation: BMC Cancer 2014 14:504
    Content type: Research article Published on:

  27. We analyzed the responses to first line treatment and clinical outcomes of metastatic breast cancer patients treated with palliative doxorubicin/cyclophosphamide (AC) according to molecular cancer subtype.

    Authors: Seong Yoon Yi, Jin Seok Ahn, Ji Eun Uhm, Do Hyoung Lim, Sang Hoon Ji, Hyun Jung Jun, Kyoung Ha Kim, Myung Hee Chang, Min Jae Park, Eun Yoon Cho, Yoon La Choi, Yeon Hee Park and Young-Hyuck Im
    Citation: BMC Cancer 2010 10:527
    Content type: Research article Published on:

  28. Systemic chemotherapy combined with steroids used as prophylactic antiemetics have been reported to induce immunosuppression. Further, herpes simplex virus-1 (HSV-1) infection has been reported to occur in pat...

    Authors: Masaaki Saito, Hirokazu Kiyozaki, Tamotu Obitsu, Hirofumi Imoto, Yusuke Taniyama, Osamu Takata and Toshiki Rikiyama
    Citation: BMC Cancer 2016 16:233
    Content type: Case report Published on:

  29. Invasive ductal and lobular carcinomas (IDC and ILC) are the most common histological types of breast cancer. Clinical follow-up data and metastatic patterns suggest that the development and progression of the...

    Authors: Gulisa Turashvili, Jan Bouchal, Karl Baumforth, Wenbin Wei, Marta Dziechciarkova, Jiri Ehrmann, Jiri Klein, Eduard Fridman, Jozef Skarda, Josef Srovnal, Marian Hajduch, Paul Murray and Zdenek Kolar
    Citation: BMC Cancer 2007 7:55
    Content type: Research article Published on:

  30. Malnutrition in gastrectomized patients receiving chemotherapy is associated with the susceptibility to chemotherapy-related adverse events. This study evaluated pre-operative nutritional status-related indice...

    Authors: Seung Hee Seo, Sung-Eun Kim, Yoon-Koo Kang, Baek-Yeol Ryoo, Min-Hee Ryu, Jae Ho Jeong, Shin Sook Kang, Mihi Yang, Jung Eun Lee and Mi-Kyung Sung
    Citation: BMC Cancer 2016 16:900
    Content type: Research article Published on:

  31. TGFβ signaling has typically been associated with suppression of tumor initiation while the role it plays in metastasis is generally associated with progression of malignancy. However, we present evidence here...

    Authors: Neka A K Simms, Ashwani Rajput, Elizabeth A Sharratt, Melanie Ongchin, Carol A Teggart, Jing Wang and Michael G Brattain
    Citation: BMC Cancer 2012 12:221
    Content type: Research article Published on:

  32. The prognosis of patients with previously treated advanced gastric or gastroesophageal junction (GEJ) cancer remains poor. Given the robust development of immunotherapy and targeted therapy during the last dec...

    Authors: Le Zhang, Weixue Wang, Shaohua Ge, Hongli Li, Ming Bai, Jingjing Duan, Yuchong Yang, Tao Ning, Rui Liu, Xia Wang, Zhi Ji, Feixue Wang, Haiyang Zhang, Yi Ba and Ting Deng
    Citation: BMC Cancer 2023 23:211
    Content type: Research Published on:

  33. Molecular markers for localized colon tumours and for prognosis following therapy are needed. Proteomics research is currently producing numerous biomarker studies with clinical potential. We investigate the p...

    Authors: Jakob Albrethsen, Rikke Bøgebo, Steen Gammeltoft, Jesper Olsen, Benny Winther and Hans Raskov
    Citation: BMC Cancer 2005 5:8
    Content type: Research article Published on:

  34. Malignant pleural mesothelioma (MPM) is an aggressive malignant tumor of mesothelial origin that shows a limited response to conventional chemotherapy and radiotherapy. Therefore, diagnosing MPM early is very ...

    Authors: Chiharu Tabata, Eisuke Shibata, Rie Tabata, Shingo Kanemura, Koji Mikami, Yoshitaka Nogi, Eriko Masachika, Tomoyuki Nishizaki and Takashi Nakano
    Citation: BMC Cancer 2013 13:205
    Content type: Research article Published on:

  35. We performed multicenter study to define clinical characteristics of noncutaneous melanomas and to establish prognostic factors patients who received curative resection.

    Authors: Hyo Song Kim, Eun Kyoung Kim, Hyun Jung Jun, Sung Yong Oh, Keon Woo Park, Do Hyoung Lim, Soon Il Lee, Jung Han Kim, Kyoung Mee Kim, Dae Ho Lee and Jeeyun Lee
    Citation: BMC Cancer 2010 10:167
    Content type: Research article Published on:

  36. The Bmi1 polycomb ring finger oncogene, a transcriptional repressor belonging to the Polycomb group of proteins plays an important role in the regulation of stem cell self-renewal and is elevated in several ca...

    Authors: Anurag N Paranjape, Sai A Balaji, Tamoghna Mandal, Esthelin Vittal Krushik, Pradeep Nagaraj, Geetashree Mukherjee and Annapoorni Rangarajan
    Citation: BMC Cancer 2014 14:785
    Content type: Research article Published on:

  37. Although the prognostic value of the Controlling Nutritional Status (CONUT) score in diffuse large B-cell lymphoma (DLBCL) has been reported in several previous studies, its clinical relevance for the presence...

    Authors: Se-Il Go, Bong-Hoi Choi, Mi Jung Park, Sungwoo Park, Myoung Hee Kang, Hoon-Gu Kim, Jung Hun Kang, Eun Jeong Jeong and Gyeong-Won Lee
    Citation: BMC Cancer 2023 23:1071
    Content type: Research Published on:

  38. The modified Glasgow Prognostic Score (mGPS) has been reported to be an important prognostic indicator in a number of tumor types, including colorectal cancer (CRC). The features of the inflammatory state thou...

    Authors: Trevor D Hamilton, Derek Leugner, Karen Kopciuk, Elijah Dixon, Francis R Sutherland and Oliver F Bathe
    Citation: BMC Cancer 2014 14:542
    Content type: Research article Published on:

  39. Glioblastoma (GBM) is a highly aggressive malignant primary brain tumor, characterized by rapid growth, diffuse infiltration of cells into both adjacent and remote brain regions, and a generalized resistance t...

    Authors: Barbara C Merk, Jennifer L Owens, Maria-Beatriz S Lopes, Corinne M Silva and Isa M Hussaini
    Citation: BMC Cancer 2011 11:184
    Content type: Research article Published on:

  40. In the management of urothelial carcinoma, patient selection for immunotherapy, particularly with immune checkpoint inhibitors such as PD-1 (programmed cell death protein 1), is important for treatment effica...

    Authors: Meng Yang, Jingwen Zhang, Dongqun Wei, Tianyi Yu, Zeyu Chen, Xin Liu and Haitao Zhu
    Citation: BMC Cancer 2024 24:196
    Content type: Research Published on:

  41. Abnormal expression of long non-coding RNAs (lncRNAs) has been shown to be associated with the pathogenesis of cancers, including colorectal cancer (CRC). It has been reported that LINC00022 is highly expresse...

    Authors: Lingling Xu, Hongmei He, Yu Shang, Xiaona Qu and Jinghua Sun
    Citation: BMC Cancer 2022 22:453
    Content type: Research Published on:

  42. Chaoshan region, a littoral area of Guangdong province in southern China, has a high incidence of esophageal squamous cell carcinoma (ESCC). At present, the prognosis of ESCC is still very poor, therefore, the...

    Authors: Zhijin Lei, Dongping Tian, Chong Zhang, Shukun Zhao and Min Su
    Citation: BMC Cancer 2016 16:410
    Content type: Research article Published on:

  44. Peritoneal dissemination is a critical prognostic factor in ovarian cancer. Although stabilized spheroid formation promotes cancer cell peritoneal dissemination in ovarian cancer, the associated oncogenes are ...

    Authors: Juri Ogishima, Ayumi Taguchi, Akira Kawata, Kei Kawana, Mitsuyo Yoshida, Yuki Yoshimatsu, Masakazu Sato, Hiroe Nakamura, Yoshiko Kawata, Akira Nishijima, Asaha Fujimoto, Kensuke Tomio, Katsuyuki Adachi, Takeshi Nagamatsu, Katsutoshi Oda, Tohru Kiyono…
    Citation: BMC Cancer 2018 18:1201
    Content type: Research article Published on:

  45. Non-muscular invasive bladder cancer (NMIBC) has a high risk of recurrence. As androgen receptor (AR) reportedly affects bladder cancer, we assessed the correlation between NMIBC recurrence and tumor AR expressio...

    Authors: Masato Yasui, Takashi Kawahara, Koji Izumi, Masahiro Yao, Yukari Ishiguro, Hitoshi Ishiguro, Hiroji Uemura and Yasuhide Miyoshi
    Citation: BMC Cancer 2019 19:331
    Content type: Research article Published on:

  46. Hepatocellular carcinoma (HCC) with inferior vena cava (IVC) involvement is a rare disease with poor prognosis. This study aimed to evaluate the outcome of HCC patients receiving radiotherapy (RT) to IVC tumor...

    Authors: Tzu-Hui Pao, Wei-Ting Hsueh, Wei-Lun Chang, Nai-Jung Chiang, Yih-Jyh Lin, Yi-Sheng Liu and Forn-Chia Lin
    Citation: BMC Cancer 2019 19:560
    Content type: Research article Published on:

  47. Vitamin D transcriptional effects were linked to tumor growth control, however, the hormone targets were determined in cell cultures exposed to supra physiological concentrations of 1,25(OH)2D3 (50-100nM). Our ai...

    Authors: Cintia Milani, Maria Lucia Hirata Katayama, Eduardo Carneiro de Lyra, JoEllen Welsh, Laura Tojeiro Campos, M Mitzi Brentani, Maria do Socorro Maciel, Rosimeire Aparecida Roela, Paulo Roberto del Valle, João Carlos Guedes Sampaio Góes, Suely Nonogaki, Rodrigo Esaki Tamura and Maria Aparecida Azevedo Koike Folgueira
    Citation: BMC Cancer 2013 13:119
    Content type: Research article Published on:

  48. Treatment of cancer patients in certified cancer centers, that meet specific quality standards in term of structures and procedures of medical care, is a national treatment goal in Germany. However, convincing...

    Authors: Martin Roessler, Jochen Schmitt, Christoph Bobeth, Michael Gerken, Kees Kleihues-van Tol, Christoph Reissfelder, Bettina M. Rau, Marius Distler, Pompiliu Piso, Christian Günster, Monika Klinkhammer-Schalke, Olaf Schoffer and Veronika Bierbaum
    Citation: BMC Cancer 2022 22:621
    Content type: Research Published on:

  49. To evaluate the safety of focal dose escalation to regions with standardized uptake value (SUV) >2.0 using intensity-modulated radiation therapy (IMRT) by comparison of radiotherapy plans using dose-volume his...

    Authors: Keiichi Jingu, Hisanori Ariga, Tomohiro Kaneta, Yoshihiro Takai, Ken Takeda, Lindel Katja, Kakutaro Narazaki, Takahiro Metoki, Keisuke Fujimoto, Rei Umezawa, Yoshihiro Ogawa, Kenji Nemoto, Masashi Koto, Masatoshi Mitsuya, Naruhiro Matsufuji, Shoki Takahashi…
    Citation: BMC Cancer 2010 10:127
    Content type: Research article Published on:

  50. Nicotinic acetylcholine receptors (nAChRs) have been reported to be overexpressed in malignancies in humans and is associated with tumorigenesis and cell migration. In previous studies of gastric cancer, alpha...

    Authors: Xuefeng Bu, Anwei Zhang, Zhengwei Chen, Xuanfeng Zhang, Riting Zhang, Chaoyun Yin, Jie Zhang, Yao Zhang and Yulan Yan
    Citation: BMC Cancer 2019 19:976
    Content type: Research article Published on:

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