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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. Colorectal cancer (CRC) is the third most prevalent cancer in China but few large-scale studies were conducted to understand CRC patients. The current study is aimed to gain a real-world perspectives of CRC pa...

    Authors: Ruihua Xu, Wei Wang, Bo Zhu, Xiaoyan Lin, Dong Ma, Lingjun Zhu, Qingchuan Zhao, Yongzhan Nie, Xiaohong Cai, Qi Li, Weijia Fang, Hongyan Li, Ning Wang, Yun Chen, Cike Peng, Honghao Fang…
    Citation: BMC Cancer 2020 20:131
    Content type: Research article Published on:

  2. Colorectal cancer is the third most common malignancy in humans and novel therapeutic approaches are urgently needed. Autophagy is an evolutionarily highly conserved cellular process by which cells collect unn...

    Authors: Bruno Christian Koehler, Adam Jassowicz, Anna-Lena Scherr, Stephan Lorenz, Praveen Radhakrishnan, Nicole Kautz, Christin Elssner, Johanna Weiss, Dirk Jaeger, Martin Schneider and Henning Schulze-Bergkamen
    Citation: BMC Cancer 2015 15:919
    Content type: Research article Published on:

  3. To compare the value of interim 18F-FLT-PET and 18F-FDG-PET for predicting treatment outcomes in patients with metastatic breast cancer after salvage therapy.

    Authors: Tzu-Pei Su, Jen-Seng Huang, Pei-Hung Chang, Kar-Wai Lui, Jason Chia-Hsun Hsieh, Shu-Hang Ng and Sheng-Chieh Chan
    Citation: BMC Cancer 2021 21:908
    Content type: Research Published on:

  4. The application of coagulation-related markers in laryngeal squamous cell carcinoma(LSCC) remains unclear. This study explored the prognostic role of coagulation markers in the progression and metastasis of LSCC.

    Authors: Qiongling Huang, Jing Chen, Yanjun Huang, Yu Xiong, Jiao Zhou, Yizheng Zhang, Ming Lu, Weipeng Hu, Feng Zheng and Chaohui Zheng
    Citation: BMC Cancer 2023 23:901
    Content type: Research Published on:

  6. Hemostatic alterations occur during the development of cancer. Plasma D-dimer is a hypercoagulability and fibrinolytic system marker that is increased in patients with various solid tumours. The aim of this st...

    Authors: Wen-Hui Chen, Lin-Quan Tang, Feng-Wei Wang, Chang-Peng Li, Xiao-Peng Tian, Xiao-Xia Huang, Shi-Juan Mai, Yi-Ji Liao, Hai-Xia Deng, Qiu-Yan Chen, Huai Liu, Lu Zhang, Shan-Shan Guo, Li-Ting Liu, Shu-Mei Yan, Chao-Feng Li…
    Citation: BMC Cancer 2014 14:583
    Content type: Research article Published on:

  7. Tamoxifen is used in hormone therapy for estrogen-receptor (ER)-positive breast cancer, but also has chemopreventative effects against ER-negative breast cancers. This study sought to investigate whether oral ...

    Authors: Xueying Sun, Ruohan Jiang, Aneta Przepiorski, Shiva Reddy, Kate P Palmano and Geoffrey W Krissansen
    Citation: BMC Cancer 2012 12:591
    Content type: Research article Published on:

  8. Colorectal cancer (CRC) is the second most common malignancy in Europe and a leading cause of cancer-related death. Almost 50% of patients with CRC develop liver metastases, which heralds a poor prognosis unle...

    Authors: Susan J Dutton, Nicola Kenealy, Sharon B Love, Harpreet S Wasan and Ricky A Sharma
    Citation: BMC Cancer 2014 14:497
    Content type: Study protocol Published on:

  9. MicroRNA-1 (miR-1) is a tumour suppressor that can inhibit cell proliferation and invasion in several cancer types. In addition, miR-1 was found to be associated with drug sensitivity. Circulating miRNAs have ...

    Authors: Jing Peng, Yanping Lin, Xiaonan Sheng, Chenwei Yuan, Yan Wang, Wenjin Yin, Liheng Zhou and Jinsong Lu
    Citation: BMC Cancer 2024 24:789
    Content type: Research Published on:

  10. The purpose of this study was to estimate the relative impact of changes in demographics, stage at detection, treatment mix, and medical technology on 5-year survival among older colorectal cancer (CRC) patients.

    Authors: Kathleen Lang, Jonathan R Korn, David W Lee, Lisa M Lines, Craig C Earle and Joseph Menzin
    Citation: BMC Cancer 2009 9:227
    Content type: Research article Published on:

  11. Breast cancer is a heterogeneous disease and personalized medicine is the hope for the improvement of the clinical outcome. Multi-gene signatures for breast cancer stratification have been extensively studied ...

    Authors: Shujun Huang, Leigh Murphy and Wayne Xu
    Citation: BMC Cancer 2018 18:473
    Content type: Research article Published on:

  12. Efficiency of colorectal carcinoma treatment by chemotherapy is diminished as the resistance develops over time in patients. The same holds true for 5-fluorouracil, the drug used in first line chemotherapy of ...

    Authors: Erika Durinikova, Zuzana Kozovska, Martina Poturnajova, Jana Plava, Zuzana Cierna, Andrea Babelova, Roman Bohovic, Silvia Schmidtova, Miroslav Tomas, Lucia Kucerova and Miroslava Matuskova
    Citation: BMC Cancer 2018 18:848
    Content type: Research article Published on:

  13. The present study aims to evaluate the efficacy and safety of apatinib monotherapy or combination therapy for patients with advanced or recurrent biliary tract cancer (BTC).

    Authors: Caiyun Nie, Huifang Lv, Yishu Xing, Beibei Chen, Weifeng Xu, Jianzheng Wang and Xiaobing Chen
    Citation: BMC Cancer 2021 21:189
    Content type: Research article Published on:

  14. The mechanism for maintaining telomere integrity is controlled by telomerase, a ribonucleoprotein enzyme that specifically restores telomere sequences, lost during replication by means of an intrinsic RNA comp...

    Authors: Blanca Murillo-Ortiz, Horacio Astudillo-De la Vega, Sebastian Castillo-Medina, JM Malacara and Luis Benitez-Bribiesca
    Citation: BMC Cancer 2006 6:206
    Content type: Research article Published on:

  15. Meprin displays multiple functions in both health and disease, due in part to its broad proteolytic activity. In this report, we explored the clinical significance and functional relevance of the expression of...

    Authors: Xiao Wang, Jian Chen, Jingtao Wang, Fudong Yu, Senlin Zhao, Yu Zhang, Huamei Tang and Zhihai Peng
    Citation: BMC Cancer 2016 16:383
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Cancer 2018 18:70

  16. Ribonucleotide reductase (RR) is an essential enzyme involved in DNA synthesis. We hypothesized that RR subunit M2 (RRM2) might be a novel prognostic and predictive biomarker for estrogen receptor (ER)-negative b...

    Authors: Hang Zhang, Xiyong Liu, Charles D Warden, Yasheng Huang, Sofia Loera, Lijun Xue, Suzhan Zhang, Peiguo Chu, Shu Zheng and Yun Yen
    Citation: BMC Cancer 2014 14:664
    Content type: Research article Published on:

  17. Malignant pleural mesothelioma (MPM) is an aggressive and rare tumour with poor prognosis. Most patients are diagnosed with advanced disease and there is a paucity of data on the humanistic burden of MPM in te...

    Authors: Adam Moore, Bryan Bennett, Gavin Taylor-Stokes, Laura McDonald and Melinda J. Daumont
    Citation: BMC Cancer 2022 22:693
    Content type: Research Published on:

  18. Gastric cancer (GC), gastroesophageal junction cancer (GEJC), and esophageal adenocarcinoma (EAC), together, are leading causes of cancer deaths worldwide. Patient health-related quality of life (HRQoL) and we...

    Authors: Hong Xiao, David Bertwistle, Keerun Khela, Chloe Middleton-Dalby and Jennifer Hall
    Citation: BMC Cancer 2023 23:186
    Content type: Research Published on:

  19. The aim was to investigate the prognostic value of MR apparent diffusion coefficients (ADC) using histogram analysis (HA) in predicting disease-free survival (DFS) of cervical cancer after chemo-radiation ther...

    Authors: Bo Zhao, Kun Cao, Xiao-Ting Li, Hai-Tao Zhu and Ying-Shi Sun
    Citation: BMC Cancer 2019 19:1115
    Content type: Research article Published on:

  20. Physical exercise and nutritional treatment are promising measures to prevent muscle wasting that is frequently observed in advanced-stage cancer patients. However, conventional exercise is not always suitable...

    Authors: Kristin Schink, Hans J. Herrmann, Raphaela Schwappacher, Julia Meyer, Till Orlemann, Elisabeth Waldmann, Bernd Wullich, Andreas Kahlmeyer, Rainer Fietkau, Dorota Lubgan, Matthias W. Beckmann, Carolin Hack, Wolfgang Kemmler, Jürgen Siebler, Markus F. Neurath and Yurdagül Zopf
    Citation: BMC Cancer 2018 18:886
    Content type: Research article Published on:

  21. P21(WAF1/Cip1) binds to cyclin-dependent kinase complexes and inhibits their activities. It was originally described as an inhibitor of cancer cell proliferation. However, many recent studies have shown that p21 ...

    Authors: Xi Xia, Quanfu Ma, Xiao Li, Teng Ji, Pingbo Chen, Hongbin Xu, Kezhen Li, Yong Fang, Danhui Weng, Yanjie Weng, Shujie Liao, Zhiqiang Han, Ronghua Liu, Tao Zhu, Shixuan Wang, Gang Xu…
    Citation: BMC Cancer 2011 11:399
    Content type: Research article Published on:

  22. Cancer of the ovary is mostly discovered at a late stage and cannot be removed by surgery alone. Therefore surgery is usually followed by adjuvant chemotherapy. However, few reliable biomarkers exist to predic...

    Authors: Raoul A. Droeser, Robert Mechera, Silvio Däster, Benjamin Weixler, Marko Kraljević, Tarik Delko, Uwe Güth, Sylvia Stadlmann, Luigi Terracciano and Gad Singer
    Citation: BMC Cancer 2016 16:639
    Content type: Research article Published on:

  23. We conducted a single-arm phase II trial to investigate the short-term efficacy and safety of apatinib combined with oxaliplatin and S-1 in the treatment of unresectable gastric cancer.

    Authors: Zaisheng Ye, Yi Zeng, Shenghong Wei, Yi Wang, Zhitao Lin, Shu Chen, Zhiwei Wang, Shanshan Chen and Luchuan Chen
    Citation: BMC Cancer 2021 21:702
    Content type: Research Published on:

  24. Ubiquitin-specific protease 32 (USP32) is a highly conserved gene that promotes cancer progression. However, its role in hepatocellular carcinoma (HCC) is not well understood. The aim of this project is to exp...

    Authors: Mengxi Xiu, Wenfang Bao, Jialin Wang, Jingde Chen, Yandong Li and Yanan Hai
    Citation: BMC Cancer 2023 23:1105
    Content type: Research Published on:

  25. Preclinical studies suggest that glucocorticoids (GCs) promote the proliferation and development of colorectal cancer. Because GCs are broadly prescribed for treatment-related adverse events in patients with l...

    Authors: Xiaoxue Huang, Zhiyuan Zheng, Bangwei Zeng, Han Xiao, Hao Zheng, Zhuangbin Lin, Jianyuan Song, Anchuan Li, Pan Chi, Yinghong Yang, Benhua Xu and Rong Zheng
    Citation: BMC Cancer 2023 23:238
    Content type: Research Published on:

  26. Owing to the low ratio of patients benefitting from immunotherapy, patient stratification becomes necessary. An accurate patient stratification contributes to therapy for different tumor types. Therefore, this...

    Authors: Zirui Zhao, Haohan Liu, Deliang Fang, Xingyu Zhou, Shaoji Zhao, Chaoyue Zhang, Jinning Ye and Jianbo Xu
    Citation: BMC Cancer 2022 22:883
    Content type: Research Published on:

  27. Head neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors which ranks the sixth incidence in the world. Although treatments for HNSCC have improved significantly in recent years, its...

    Authors: Ce Li, Rui Guan, Wenming Li, Dongmin Wei, Shengda Cao, Fen Chang, Qun Wei, Ran Wei, Long Chen, Chenyang Xu, Kainan Wu and Dapeng Lei
    Citation: BMC Cancer 2023 23:840
    Content type: Research Published on:

  28. Better breast cancer prognostication may improve selection of patients for adjuvant therapy. We conducted a retrospective follow-up study in which we investigated sera of high-risk primary breast cancer patien...

    Authors: Marie-Christine W Gast, Harm van Tinteren, Marijke Bontenbal, René QGCM van Hoesel, Marianne A Nooij, Sjoerd Rodenhuis, Paul N Span, Vivianne CG Tjan-Heijnen, Elisabeth GE de Vries, Nathan Harris, Jos WR Twisk, Jan HM Schellens and Jos H Beijnen
    Citation: BMC Cancer 2008 8:389
    Content type: Research article Published on:

  29. Optimising breast cancer treatment remains a challenge. Resistance to therapy is a major problem in both ER- and ER+ breast cancer. Tumour recurrence after chemotherapy and/or targeted therapy leads to more ag...

    Authors: Lana McClements, Stephanie Annett, Anita Yakkundi, Martin O’Rourke, Andrea Valentine, Nermeen Moustafa, Abdelrahim Alqudah, Bruno M. Simões, Fiona Furlong, Amy Short, Stuart A. McIntosh, Helen O. McCarthy, Robert B. Clarke and Tracy Robson
    Citation: BMC Cancer 2019 19:351
    Content type: Research article Published on:

  30. Addition of oxaliplatin to capecitabine remains controversial for locally advanced rectal cancer (LARC). And cumulative oxaliplatin dose (COD) varied among clinical trials showing different therapeutic effects...

    Authors: Hui Chang, Ya-lan Tao, Wu Jiang, Chen Chen, Shi-liang Liu, Wei-jun Ye and Yuan-hong Gao
    Citation: BMC Cancer 2020 20:498
    Content type: Research article Published on:

  31. Breast cancer is the most common malignancy in women, and neoadjuvant chemotherapy has been recommended to the patients with locally advanced breast cancer as the initial treatments. Long non-coding RNA (lncRN...

    Authors: Battseren Bayarmaa, Ziping Wu, Jing Peng, Yan Wang, Shuguang Xu, Tingting Yan, Wenjin Yin, Jinsong Lu and Liheng Zhou
    Citation: BMC Cancer 2019 19:877
    Content type: Research article Published on:

  32. At intensive care unit (ICU) admission, the issue about prognosis of critically ill cancer patients is of clinical interest, especially after ICU discharge. Our objective was to assess the factors associated w...

    Authors: Hubert Gheerbrant, Jean-François Timsit, Nicolas Terzi, Stéphane Ruckly, Mathieu Laramas, Matteo Giaj Levra, Emmanuelle Jacquet, Loic Falque, Denis Moro-Sibilot and Anne-Claire Toffart
    Citation: BMC Cancer 2021 21:9
    Content type: Research article Published on:

  33. Immune checkpoint inhibitors (ICI)-based combination strategies have improved the survival outcomes in advanced non-small cell lung cancers; however, data regarding their efficacy remains limited for uncommon ...

    Authors: Lianxi Song, Fei Zhou, Tian Xu, Liang Zeng, Qing Xia, Zhan Wang, Li Deng, Yizhi Li, Haoyue Qin, Huan Yan, Zhe Huang, Jinye Mi, Qinqin Xu, Nong Yang, Caicun Zhou and Yongchang Zhang
    Citation: BMC Cancer 2023 23:443
    Content type: Research Published on:

  34. Peritoneal carcinomatosis is regarded as a common sign of advanced tumor stage, tumor progression or local recurrence of appendiceal and colorectal cancer and is generally associated with poor prognosis. Altho...

    Authors: Gabriel Glockzin, Justine Rochon, Dirk Arnold, Sven A Lang, Frank Klebl, Florian Zeman, Michael Koller, Hans J Schlitt and Pompiliu Piso
    Citation: BMC Cancer 2013 13:67
    Content type: Study protocol Published on:

  35. DNA aneuploidy has attracted growing interest in clinical practice. Nevertheless, its prognostic value in gastric cancer patients remains controversial. This meta-analysis aims to explore the impact of DNA plo...

    Authors: Jing Xu, Ruolin Zhu, Lulu Fan, Shangqing Ge, Wei Wei, Xiaoqiu Li, Liangshan Da, Zhenya Jia, Zhiyan Zhao, Jie Ning, Jie Da, Wanren Peng, Kangsheng Gu and Guoping Sun
    Citation: BMC Cancer 2019 19:650
    Content type: Research article Published on:

  36. The aim was to compare two standard chemotherapy regimens combined with bevacizumab as first-line treatment in patients with metastatic colorectal cancer.

    Authors: Dimitrios Pectasides, George Papaxoinis, Konstantine T Kalogeras, Anastasia G Eleftheraki, Ioannis Xanthakis, Thomas Makatsoris, Epaminondas Samantas, Ioannis Varthalitis, Pavlos Papakostas, Nikitas Nikitas, Christos N Papandreou, George Pentheroudakis, Eleni Timotheadou, Angelos Koutras, Joseph Sgouros, Dimitrios Bafaloukos…
    Citation: BMC Cancer 2012 12:271
    Content type: Research article Published on:

  37. RNASET2 has been identified as an oncogene with anti-angiogenic and immunomodulatory effects in a variety of cancers, but its function in clear cell renal cell carcinoma (ccRCC) is still not well understood.

    Authors: Yifu Liu, Zhicheng Zhang, Ping Xi, Ru Chen, Xiaofeng Cheng, Ji Liu, Qiqi Zhu, Yechen Nie, Ting Sun, Binbin Gong and Siyuan Wang
    Citation: BMC Cancer 2023 23:837
    Content type: Research Published on:

  38. DNA methylation is frequently observed in the development and progression of many human tumors as well as renal cell cancer (RCC). Tumor Associated Calcium Signal Transducer 2 (TACSTD2) participates in cell cy...

    Authors: Olga Katzendorn, Inga Peters, Natalia Dubrowinskaja, Hossein Tezval, Pouriya Faraj Tabrizi, Christoph A. von Klot, Jörg Hennenlotter, Marcel Lafos, Markus A. Kuczyk and Jürgen Serth
    Citation: BMC Cancer 2021 21:444
    Content type: Research Published on:

  39. Metastasis is responsible for the majority of deaths in a variety of cancer types, including breast cancer. Although several factors or biomarkers have been identified to predict the outcome of patients with b...

    Authors: Liang Zeng, Xiyun Deng, Jingmin Zhong, Li Yuan, Xiaojun Tao, Sai Zhang, Yong Zeng, Guangchun He, Pingping Tan and Yongguang Tao
    Citation: BMC Cancer 2019 19:831
    Content type: Research article Published on:

  40. To determine the role and rational application of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) adjuvant therapy in patients with completely resected stage IB-IIIA EGFR-mutant non-small...

    Authors: Shu-Ling Zhang, Xiao-Fang Yi, Le-Tian Huang, Li Sun, Jie-Tao Ma and Cheng-Bo Han
    Citation: BMC Cancer 2023 23:719
    Content type: Research Published on:

  41. Tumor micro-angiogenesis and lymphangiogenesis are effective prognostic predictors in many solid malignancies. However, its role on Xp11.2 translocation RCC has not been fully elucidated. Herein, we purposed t...

    Authors: Wenliang Ma, Jun Yang, Ning Liu, Xiaohong Pu, Feng Qu, Linfeng Xu, Xiaozhi Zhao, Xiaogong Li, Gutian Zhang, Hongqian Guo, Dongmei Li and Weidong Gan
    Citation: BMC Cancer 2020 20:1182
    Content type: Research article Published on:

  42. Acute Limb Ischemia (ALI) carries a high morbidity and mortality rate that is compounded in the cancer patient. Though it is a relatively uncommon event, it is of extremely high adverse impact and carries poor...

    Authors: Yolanda Bryce, Amoateng Emmanuel Jr, Christopher Agrusa, Etay Ziv, Christopher Harnain, Samantha Huq and Ernesto Santos Martin
    Citation: BMC Cancer 2021 21:916
    Content type: Research Published on:

  43. The aim of this study was to evaluate the prognostic potential of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) tumor tissue levels and examine the association b...

    Authors: Marko Jevrić, Ivana Z. Matić, Ana Krivokuća, Marija Đorđić Crnogorac, Irina Besu, Ana Damjanović, Mirjana Branković-Magić, Zorka Milovanović, Dušica Gavrilović, Snezana Susnjar, Darija Kisić Tepavčević and Tatjana Stanojković
    Citation: BMC Cancer 2019 19:71
    Content type: Research article Published on:

  44. The protein kinases CK2 and PIM-1 are involved in cell proliferation and survival, the cell cycle, and drug resistance, and they are found overexpressed in virtually all types of human cancer, including breast...

    Authors: Mirosława Koronkiewicz, Zygmunt Kazimierczuk and Andrzej Orzeszko
    Citation: BMC Cancer 2022 22:1069
    Content type: Research Published on:

  45. Cancer recurrence is one of the most concerning clinical problems of cholangiocarcinoma (CCA) patients after treatment. However, an identification of predictive factor on Opisthorchis viverrini (OV)-associated CC...

    Authors: Sureerat Padthaisong, Malinee Thanee, Nisana Namwat, Jutarop Phetcharaburanin, Poramate Klanrit, Narong Khuntikeo, Attapol Titapun and Watcharin Loilome
    Citation: BMC Cancer 2020 20:154
    Content type: Research article Published on:

  46. LncRNA MEG3 expressed abnormally in various cancers including breast cancer, but no studies reported the correlation between MEG3 SNPs and breast cancer susceptibility among Chinese women.

    Authors: Yi Zheng, Meng Wang, Shuqian Wang, Peng Xu, Yujiao Deng, Shuai Lin, Na Li, Kang Liu, Yuyao Zhu, Zhen Zhai, Ying Wu, Zhijun Dai and Gaixia Zhu
    Citation: BMC Cancer 2020 20:659
    Content type: Research article Published on:

  48. Extracellular vesicles (EVs) have been revealed to facilitate the development of oral squamous cavity cell carcinoma (OCSCC), while its supporting role in lymph node metastases is under continuous investigatio...

    Authors: Tianzhu Lv, Hongjing Liu, Ling Mao, Yanrong Song, Lili Liao, Kun Zhong, Binbin Shuai, Yingkun Luo, Tingting Guo, Wentao Huang and Shenyingjie Zhang
    Citation: BMC Cancer 2024 24:113
    Content type: Research Published on:

  49. Heat Shock Proteins (HSPs), a family of genes with key roles in proteostasis, have been extensively associated with cancer behaviour. However, the HSP family is quite large and many of its members have not bee...

    Authors: Felipe C. M. Zoppino, Martin E. Guerrero-Gimenez, Gisela N. Castro and Daniel R. Ciocca
    Citation: BMC Cancer 2018 18:700
    Content type: Research article Published on:

  50. CRBP-1, a cytosolic chaperone of vitamin A, is identified in a serious number of cancers; however, its biological role in hepatocellular carcinoma (HCC) needs to be further explored. The aim of our present stu...

    Authors: Xiangye Liu, Wenhua Shan, Tingting Li, Xiaoge Gao, Fanyun Kong, Hongjuan You, Delong Kong, Shuxi Qiao and Renxian Tang
    Citation: BMC Cancer 2021 21:1224
    Content type: Research Published on:

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