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  1. Adenocarcinoma of the ampulla of Vater (AoV) is one of the rare periampullary cancers, and due to its anatomical location, it is categorized into various histologic subtypes. Its rarity and diversity pose chal...

    Authors: Seunghwan Lee, Se Jun Park, Kabsoo Shin, Tae Ho Hong, In-Ho Kim and Myung Ah Lee
    Citation: BMC Cancer 2024 24:634
    Content type: Research Published on:

  2. PD-L1 overexpression is commonly observed in various malignancies and is strongly correlated with poor prognoses for cancer patients. Moreover, PD-L1 has been shown to play a significant role in promoting angi...

    Authors: Wenjuan Li, Jiatao Wu, Qianhao Jia, Yuqi Shi, Fan Li, Linxiang Zhang, Fan Shi, Xiaojing Wang and Shiwu Wu
    Citation: BMC Cancer 2024 24:633
    Content type: Research Published on:

  3. Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) combined with endocrine therapy (ET) are currently recommended by the National Comprehensive Cancer Network (NCCN) guidelines and the European Society for M...

    Authors: Veronique Lambert, Sarah Kane, Belal Howidi, Bao-Ngoc Nguyen, David Chandiwana, Yan Wu, Michelle Edwards and Imtiaz A. Samjoo
    Citation: BMC Cancer 2024 24:631
    Content type: Systematic Review Published on:

  4. Tumor morphology, immune function, inflammatory levels, and nutritional status play critical roles in the progression of intrahepatic cholangiocarcinoma (ICC). This multicenter study aimed to investigate the a...

    Authors: Haofeng Zhang, Guan Huang, Qingshan Li, Yanbo Wang, Zhenwei Yang, Pengyu Chen, Hao Yuan, Kunlun Chen, Bo Meng and Haibo Yu
    Citation: BMC Cancer 2024 24:630
    Content type: Research Published on:

  5. CCR8-expressing regulatory T cells (Tregs) are selectively localized within tumors and have gained attention as potent suppressors of anti-tumor immunity. This study focused on CCR8+ Tregs and their interaction w...

    Authors: Yoshinori Hayashi, Azumi Ueyama, Soichiro Funaki, Koichi Jinushi, Naoko Higuchi, Hitomi Morihara, Michinari Hirata, Yoji Nagira, Takuro Saito, Atsunari Kawashima, Kota Iwahori, Yasushi Shintani and Hisashi Wada
    Citation: BMC Cancer 2024 24:627
    Content type: Research Published on:

  6. Cervical cancer is a tumor with high morbidity and mortality. The importance of inflammatory and metabolic parameters affecting progression-free survival (PFS) and overall survival (OS) has been investigated m...

    Authors: Mehmet Emin Buyukbayram, Zekeriya Hannarici, Aykut Turhan, Alperen Akansel Caglar, Pınar Çoban Esdur, Mehmet Bilici, Salim Basol Tekin and Burak Erdemci
    Citation: BMC Cancer 2024 24:626
    Content type: Research Published on:

  7. Obesity is associated with chronic low-grade inflammation, which is linked to cancer development. Abdominal obesity (a body mass index, ABSI), however, has unusually been associated inversely with cutaneous ma...

    Authors: Sofia Christakoudi, Konstantinos K. Tsilidis and Elio Riboli
    Citation: BMC Cancer 2024 24:625
    Content type: Research Published on:

  8. Hepatocellular carcinoma (HCC) has a high mortality rate, and the mechanisms underlying tumor development and progression remain unclear. However, inactivated tumor suppressor genes might play key roles. DNA m...

    Authors: Yuanxiao Du, Yuqiu Xu, Xuefeng Guo, Chao Tan, Xiaonian Zhu, Guoyu Liu, Xiao Lyu and Chunhua Bei
    Citation: BMC Cancer 2024 24:624
    Content type: Research Published on:

  10. International guidelines recommend ivosidenib followed by modified FOLFOX (mFOLFOX) for advanced intrahepatic cholangiocarcinoma (ICC) with isocitrate dehydrogenase 1 (IDH1) mutations. Taiwan National Health Insu...

    Authors: Kuei-An Chen, Wei-Ming Huang, Eric Yi-Ting Chen, Pei-Kuan Ho, Chen-Han Chueh, Yu-Wen Wen, Ming-Huang Chen, Nai-Jung Chiang and Yi-Wen Tsai
    Citation: BMC Cancer 2024 24:622
    Content type: Research Published on:

  11. Diffuse large B-cell lymphomas (DLBCLs) display high molecular heterogeneity, but the International Prognostic Index (IPI) considers only clinical indicators and has not been updated to include molecular data....

    Authors: Huilin Peng, Mengmeng Su, Xiang Guo, Liang Shi, Tao Lei, Haifeng Yu, Jieyu Xu, Xiaohua Pan and Xi Chen
    Citation: BMC Cancer 2024 24:621
    Content type: Research Published on:

  12. The role of adjuvant transcatheter arterial chemoembolization (TACE) following repeated resection/ablation for recurrent hepatocellular carcinoma (HCC) remains uncertain. The aim of this study was to assess th...

    Authors: Kaiquan Huang, Tao Qian, Wen Chen, Mengyi Lao, Huiliang Li, Wei-Chiao Lin, Bryan Wei Chen, Xueli Bai, Shunliang Gao, Tao Ma and Tingbo Liang
    Citation: BMC Cancer 2024 24:620
    Content type: Research Published on:

  13. Breast cancer is one of the common malignancies in women. Evidence has demonstrated that FBXO45 plays a pivotal role in oncogenesis and progression. However, the role of FBXO45 in breast tumorigenesis remains ...

    Authors: Mengmeng Zheng, Linfeng Wu, Rongyao Xiao, Jiaohao Cai, Weike Chen and Shurong Shen
    Citation: BMC Cancer 2024 24:619
    Content type: Research Published on:

  15. Hepatocellular carcinoma (HCC) presents a significant threat to individuals and healthcare systems due to its high recurrence rate. Accurate prognostic models are essential for improving patient outcomes. Gamm...

    Authors: Mingxiu Ma, Kailing Xie, Tianqiang Jin and Feng Xu
    Citation: BMC Cancer 2024 24:617
    Content type: Research Published on:

  16. DNA-Damaged Binding protein 2 (DDB2) is a protein involved in the early step of Nucleotide Excision Repair. Recently, it has been reported that DDB2 is involved in epithelial-to-mesenchymal transition (EMT), k...

    Authors: Paola Perucca, Elisabetta Bassi, Martina Vetro, Anna Tricarico, Ennio Prosperi, Lucia Anna Stivala and Ornella Cazzalini
    Citation: BMC Cancer 2024 24:616
    Content type: Research Published on:

  17. Breast cancer (BC) is the most commonly diagnosed cancer in women. Treatment approaches that differ between estrogen-positive (ER+) and triple-negative BC cells (TNBCs) and may subsequently affect cancer bioma...

    Authors: Rita El Habre, Rita Aoun, Roula Tahtouh and George Hilal
    Citation: BMC Cancer 2024 24:615
    Content type: Research Published on:

  18. Our study was to investigate the impact of taurolactone, a novel anti-tumor and anti-angiogenic drug, on AGGF1, an angiogenic factor, and angiogenesis mimicry in patients diagnosed with hepatocellular carcinom...

    Authors: Shaoping Liu, Yinzhi Wei, Lei Nie, Ze Tang, Qi Lu and Qun Liang
    Citation: BMC Cancer 2024 24:614
    Content type: Research Published on:

  19. The intricate balance between the advantages and risks of low-dose computed tomography (LDCT) impedes the utilization of lung cancer screening (LCS). Guiding shared decision-making (SDM) for well-informed choi...

    Authors: Xiujing Lin, Fangfang Wang, Yonglin Li, Fang Lei, Weisheng Chen, Rachel H. Arbing, Wei-Ti Chen and Feifei Huang
    Citation: BMC Cancer 2024 24:613
    Content type: Research Published on:

  20. Glioblastoma multiforme (GBM) is a type of fast-growing brain glioma associated with a very poor prognosis. This study aims to identify key genes whose expression is associated with the overall survival (OS) i...

    Authors: Parisa Azimi, Taravat Yazdanian and Abolhassan Ahmadiani
    Citation: BMC Cancer 2024 24:612
    Content type: Systematic Review Published on:

  21. RNA interactomes and their diversified functionalities have recently benefited from critical methodological advances leading to a paradigm shift from a conventional conception on the regulatory roles of RNA in...

    Authors: Jing-Yu Wang, Xiao-Ping Zhang, Hong-Kun Zhou, Hong-Xin Cai, Jin-Biao Xu, Bao-Gang Xie, Jean-Paul Thiery and Wu Zhou
    Citation: BMC Cancer 2024 24:611
    Content type: Research Published on:

  22. Venous thromboembolism (VTE) is a major complication of breast cancer surgical patients. Assessing VTE awareness enables medical staff to tailor educational programs that improve patient self-management and re...

    Authors: Qiuzhou Wang, Hongxiu Chen, Qingyu Yang, Jiajia Qiu, Sijin Guo, Yi Zhou, Lihong Huang, Chen Li and Xiaoxia Zhang
    Citation: BMC Cancer 2024 24:610
    Content type: Research Published on:

  23. The modeled CA-125 elimination constant K (KELIM) is a potential marker of tumor chemosensitivity in ovarian cancer patients treated with neoadjuvant chemotherapy (NACT) before interval surgery. The objective ...

    Authors: Cheng Li, Qiulin Cui, Xuanhui Wang, Shuzhong Yao, Hua Tu and Ming Chen
    Citation: BMC Cancer 2024 24:609
    Content type: Research Published on:

  24. Lung cancer is the second most diagnosed cancer in the world. Up to 84% of diagnosed patients have malnutrition, which can negatively affect quality of life and survival and may worsen with neoadjuvant treatme...

    Authors: Melania Prete, Giada Ballarin, Giuseppe Porciello, Aniello Arianna, Assunta Luongo, Valentina Belli, Luca Scalfi and Egidio Celentano
    Citation: BMC Cancer 2024 24:608
    Content type: Systematic Review Published on:

  26. Esophageal cancer brings emotional changes, especially anxiety to patients. Co-existing anxiety makes the surgery difficult and may cause complications. This study aims to evaluate effects of anxiety in postop...

    Authors: Yu Rong, Yanbing Hao, Dong Wei, Yanming Li, Wansheng Chen, Li Wang and Tian Li
    Citation: BMC Cancer 2024 24:606
    Content type: Research Published on:

  28. Cancer is a leading global cause of death. Conventional cancer treatments like surgery, radiation, and chemotherapy have associated side effects. Ferroptosis, a nonapoptotic and iron-dependent cell death, has ...

    Authors: Shen Li, Kai Tao, Hong Yun, Jiaqing Yang, Yuanling Meng, Fan Zhang and Xuelei Ma
    Citation: BMC Cancer 2024 24:604
    Content type: Research Published on:

  29. Immunotherapy or apatinib alone has been used as third-line adjuvant therapy for advanced or metastatic gastric/gastroesophageal junction (G/GEJ) tumors, but the efficacy of combining them with each other for ...

    Authors: Jincheng Wang, Jie Lin, Ruimin Wang, Ti Tong and Yinghao Zhao
    Citation: BMC Cancer 2024 24:603
    Content type: Systematic Review Published on:

  31. Chronic obstructive pulmonary disease (COPD) is a significant global health issue, suspected to elevate the risk for various cancers. This study sought to discern whether COPD serves as a risk marker or a caus...

    Authors: Shixia Liao, Yanwen Wang, Jian Zhou, Yuting Liu, Shuangfei He, Lanying Zhang, Maomao Liu, Dongmei Wen, Pengpeng Sun, Guangbing Lu, Qi Wang, Yao Ouyang and Yongxiang Song
    Citation: BMC Cancer 2024 24:601
    Content type: Research Published on:

  32. Exercise-based cancer rehabilitation via digital technologies can provide a promising alternative to centre-based exercise training, but data for cancer patients and survivors are limited. We conducted a meta-...

    Authors: Ladislav Batalik, Katerina Chamradova, Petr Winnige, Filip Dosbaba, Katerina Batalikova, Daniela Vlazna, Andrea Janikova, Garyfallia Pepera, Hammoda Abu-Odah and Jing Jing Su
    Citation: BMC Cancer 2024 24:600
    Content type: Systematic Review Published on:

  33. To determine the impact of the loco-regional treatment modality, on the loco-regional recurrence (LRR) rates and overall survival (OS) in breast cancer patients younger than 40 years.

    Authors: Rimoun R. Boutrus, Yasser A. Abdelazim, Toka Mohammed, Mohammed Bayomy, Maher H. Ibraheem, Alaadin Hussein and Medhat El Sebaie
    Citation: BMC Cancer 2024 24:599
    Content type: Research Published on:

  34. Results regarding whether it is essential to incorporate genetic variants into risk prediction models for esophageal cancer (EC) are inconsistent due to the different genetic backgrounds of the populations stu...

    Authors: Haiyan Liu, Keming Li, Junfen Xia, Jicun Zhu, Yifan Cheng, Xiaoyue Zhang, Hua Ye and Peng Wang
    Citation: BMC Cancer 2024 24:598
    Content type: Research Published on:

  35. With the increasing of novel therapeutics for the treatment of Biliary Tract Cancers (BTC), and the need to assess their socio-economic impacts for national licence approvals, it is as important as ever to hav...

    Authors: Valentina Zanuso, Tamsin Nash, Raffaella Casolino, Gregory Armstrong, Ona Pallise, Jen Milne and Chiara Braconi
    Citation: BMC Cancer 2024 24:597
    Content type: Research Published on:

  36. Oesophageal squamous cell carcinoma is one of the most commonly diagnosed carcinomas in China, and postoperative radiotherapy plays an important role in improving the prognosis of patients. Carcinomas in diffe...

    Authors: Rongxu Du, Songqing Fan, Dan Yang, Xiaobin Wang, Xia Hou, Cheng Zeng, Dan Guo, Rongrong Tian, Leilei Jiang, Xin Dong, Rong Yu, Huiming Yu, Shuchai Zhu, Jie Li and Anhui Shi
    Citation: BMC Cancer 2024 24:596
    Content type: Research Published on:

  37. Cervical cancer is the fourth most common cancer among women worldwide, both for incidence and mortality. Prevention relies on screening with a Pap test to detect precancerous lesions, which can then be treate...

    Authors: Elisabeth Lyonnais, Solène Vigoureux, Béatrice Blondel, Sophie Wylomanski and Elie Azria
    Citation: BMC Cancer 2024 24:595
    Content type: Research Published on:

  39. Total pelvic exenteration (TPE), an en bloc resection is an ultraradical operation for malignancies, and refers to the removal of organs inside the pelvis, including female reproductive organs, lower urologica...

    Authors: Arezoo Esmailzadeh, Mohammad Sadegh Fakhari, Nafise Saedi, Nasim Shokouhi and Amir Almasi-Hashiani
    Citation: BMC Cancer 2024 24:593
    Content type: Systematic Review Published on:

  40. Human papillomavirus (HPV) vaccination protects against HPV-associated cancers and genital warts. Healthy People 2030 goal for HPV vaccine uptake is 80%, but as of 2021, only 58.5% of adolescents are up to dat...

    Authors: Courtney N. Petagna, Stephen Perez, Erica Hsu, Brenda M. Greene, Ionie Banner, Robert A. Bednarczyk and Cam Escoffery
    Citation: BMC Cancer 2024 24:592
    Content type: Research Published on:

  41. There is little evidence that dietary supplements are beneficial for patients with breast cancer; therefore, they are usually not recommended by treatment guidelines. The aim of the present analysis was to ass...

    Authors: Dagmar Hauner, Anna Mang, Lara Donik, Florian Schederecker, Dorothy Meyer, Brigitte Rack, Wolfgang Janni and Hans Hauner
    Citation: BMC Cancer 2024 24:591
    Content type: Research Published on:

  42. In Palestine, colorectal cancer (CRC) is the second most common cause of cancer-related mortality after lung cancer. No studies have examined the relationship between CRC awareness and attitudes. This study ai...

    Authors: Mohamedraed Elshami, Mohammad Fuad Dwikat, Ibrahim Al-Slaibi, Mohammed Alser, Maram Elena Albandak, Mohammed Ayyad, Shoruq Ahmed Naji, Balqees Mustafa Mohamad, Wejdan Sudki Isleem, Adela Shurrab, Bashar Yaghi, Yahya Ayyash Qabaja, Fatma Khader Hamdan, Raneen Raed Sweity, Remah Tayseer Jneed, Khayria Ali Assaf…
    Citation: BMC Cancer 2024 24:590
    Content type: Research Published on:

  44. Combination therapy is the primary treatment for unresectable hepatocellular carcinoma (u-HCC). The hepatic functional reserve is also critical in the treatment of HCC. In this study, u-HCC was treated with co...

    Authors: Yongqiang Xiao, Wei Deng, Laihui Luo, Guoqing Zhu, Jin Xie, Yu Liu, Renhua Wan, Wu Wen, Zhigao Hu and Renfeng Shan
    Citation: BMC Cancer 2024 24:588
    Content type: Research Published on:

  45. YAP and TAZ, the Hippo pathway terminal transcriptional activators, are frequently upregulated in cancers. In tumor cells, they have been mainly associated with increased tumorigenesis controlling different as...

    Authors: Věra Slaninová, Lisa Heron-Milhavet, Mathilde Robin, Laura Jeanson, Adam Aissanou, Diala Kantar, Diego Tosi, Laurent Bréhélin, Céline Gongora and Alexandre Djiane
    Citation: BMC Cancer 2024 24:587
    Content type: Research Published on:

  46. Observational study investigated the association between pernicious anemia (PA) and cancers. However, with the exception of gastric cancer, the results are mostly contradictory. The purpose of this study was t...

    Authors: Bangwei Che, Shenglan Yuan, Hongyan Zhang, Jiancheng Zhai, Yang Zhang, Chuanchuan Wu and Kaifa Tang
    Citation: BMC Cancer 2024 24:586
    Content type: Research Published on:

  47. The optimal timing for surgery following neoadjuvant immunochemotherapy for lung squamous cell carcinoma appears to be a topic of limited data. Many clinical studies lack stringent guidelines regarding this ti...

    Authors: Chen Gu, Xiao Teng, Xuqi sun, Jiacong Liu, Ziyue Zhu, Lichen Zhang, Zhigang Wu, Rui Zou, Jinghua Pang and Xiayi Lyu
    Citation: BMC Cancer 2024 24:585
    Content type: Research Published on:

  48. In chronic lymphocytic leukaemia (CLL), comorbidities assessed by the CLL comorbidity index (CLL-CI) have been associated with outcomes in Western cohorts. We conducted a retrospective analysis of an unselecte...

    Authors: Salem H. Alshemmari, Ahmad AlSarraf, Andy Kaempf and Alexey V. Danilov
    Citation: BMC Cancer 2024 24:584
    Content type: Research Published on:

  49. Local recurrence after surgery and radiochemotherapy seriously affects the prognosis of locally advanced rectal cancer (LARC) patients. Studies on molecular markers related to the radiochemotherapy sensitivity...

    Authors: Heng Zhang, Xiaofan Li, Wanjun Sun, Haoren Qin, Haipeng Li, Hao Yan, Huaqing Wang, Xipeng Zhang, Shiwu Zhang and Hui Wang
    Citation: BMC Cancer 2024 24:582
    Content type: Research Published on:

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