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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. Oxidative stress is a widely seen phenomenon in several carcinomas. Increasing evidence also suggests that it has a significant role in the development of epithelial ovarian carcinoma (EOC). 8-Hydroxydeoxyguan...

    Authors: Marjo Pylväs-Eerola, Peeter Karihtala and Ulla Puistola
    Citation: BMC Cancer 2015 15:493
    Content type: Research article Published on:

  2. The epidemiological investigation of different cancer types in the global population has reported a decreased risk of bladder cancer (BLCA) in Parkinson’s diseases (PD). SNCA a critical gene in PD pathology have ...

    Authors: Zhengcun Wu, Chengxing Xia, Chao Zhang, Delin Yang and Kaili Ma
    Citation: BMC Cancer 2022 22:330
    Content type: Research Published on:

  3. To investigate the efficacy and safety of interval debulking surgery (IDS) combined with dense hyperthermic intraperitoneal chemotherapy (HIPEC) with cisplatin in Chinese patients with FIGO stage III serous ep...

    Authors: Xiaoli He, Li Wei, Rui Li, Shuang Jing, Linlin Jia, Danwei Ji, Yali Li, Yue Wang and Yongxia Zhu
    Citation: BMC Cancer 2021 21:738
    Content type: Research article Published on:

  4. Patients with V-Raf murine sarcoma viral oncogene homolog B1 (BRAF) V600E-mutated advanced colorectal cancer (CRC) have a poor prognosis, and treatment options that can improve outcome are still under investig...

    Authors: Qianhao Meng, Jian Zhao, Yuanyuan Yu, Ke Wang, Jing Ren, Chang Xu, Yusheng Wang and Guangyu Wang
    Citation: BMC Cancer 2023 23:191
    Content type: Research Published on:

  6. Brain metastases (BM) from colorectal cancer (CRC) are a rare event. However, the implications for affected patients are severe, and the incidence has been reported to be increasing. For clinicians, knowledge ...

    Authors: Troels Dreier Christensen, Karen-Lise Garm Spindler, Jesper Andreas Palshof and Dorte Lisbet Nielsen
    Citation: BMC Cancer 2016 16:260
    Content type: Research article Published on:

  7. Mesothelin (MSLN) is a cell-surface glycoprotein found in various solid tumours. Cancer therapies targeting MSLN have been developed in recent years; however, the available information on MSLN expression in ce...

    Authors: Shigemasa Takamizawa, Shu Yazaki, Yuki Kojima, Hiroshi Yoshida, Rui Kitadai, Tadaaki Nishikawa, Tatsunori Shimoi, Kazuki Sudo, Hitomi Sumiyoshi Okuma, Maki Tanioka, Emi Noguchi, Masaya Uno, Mitsuya Ishikawa, Tomoyasu Kato, Yasuhiro Fujiwara and Kan Yonemori
    Citation: BMC Cancer 2022 22:1215
    Content type: Research article Published on:

  8. Cathepsin X is a cysteine protease involved in mechanisms of malignant progression. It is secreted from tumour cells as a proenzyme and may serve to predict the disease status and risk of death for cancer pati...

    Authors: Tjaša Vižin, Ib Jarle Christensen, Michael Wilhelmsen, Hans Jørgen Nielsen and Janko Kos
    Citation: BMC Cancer 2014 14:259
    Content type: Research article Published on:

  9. PDE9A (Phosphodiesterase 9A) plays an important role in proliferation of cells, their differentiation and apoptosis via intracellular cGMP (cyclic guanosine monophosphate) signaling. The expression pattern of ...

    Authors: Tasmina Ferdous Susmi, Atikur Rahman, Md. Moshiur Rahman Khan, Farzana Yasmin, Md. Shariful Islam, Omaima Nasif, Sulaiman Ali Alharbi, Gaber El-Saber Batiha and Mohammad Uzzal Hossain
    Citation: BMC Cancer 2021 21:577
    Content type: Research Published on:

  10. Circulating tumor cells (CTCs) detection has previously been used for diagnosing gastric cancer. However, the previous studies failed to make an agreement whether the detection of CTCs contributes to the diagn...

    Authors: Lanhua Tang, Shushan Zhao, Wei Liu, Nicholas F Parchim, Jin Huang, Youhong Tang, Pingping Gan and Meizuo Zhong
    Citation: BMC Cancer 2013 13:314
    Content type: Research article Published on:

  11. Clear cell carcinoma of the kidney is a common urological malignancy characterized by poor patient prognosis and treatment outcomes. Modulation of vasculogenic mimicry in tumor cells alters the tumor microenvi...

    Authors: Yuming Gu, Qinqin Huang, Yun Wang, Haixia Wang, Zhenhua Xiang, Yu Xu, Xin Wang, Weiguo Liu and Aiju Wang
    Citation: BMC Cancer 2024 24:420
    Content type: Research Published on:

  12. The tripartite motif (TRIM) family proteins exhibit oncogenic roles in various cancers. The roles of TRIM27, a member of the TRIM super family, in renal cell carcinoma (RCC) remained unexplored. In the current...

    Authors: Chengwu Xiao, Wei Zhang, Meimian Hua, Huan Chen, Bin Yang, Ye Wang and Qing Yang
    Citation: BMC Cancer 2021 21:841
    Content type: Research Published on:

  13. This study aimed to evaluate the utility of inflammation-based prognostic scores (IBPS) and systemic immune-inflammation index (SII) in the treatment of oral cancer patients.

    Authors: Kosei Kubota, Ryohei Ito, Norihiko Narita, Yusuke Tanaka, Ken Furudate, Natsumi Akiyama, Chuang Hao Chih, Shotaro Komatsu and Wataru Kobayashi
    Citation: BMC Cancer 2022 22:368
    Content type: Research Published on:

  14. As a marker of differentiation, Killer cell lectin like receptor G1 (KLRG1) plays an inhibitory role in human NK cells and T cells. However, its clinical role remains inexplicit. This work intended to investig...

    Authors: Xiaodong Yang, Yuexin Zheng, Zhihai Han and Xiliang Zhang
    Citation: BMC Cancer 2021 21:752
    Content type: Research article Published on:

  15. The human microbiome is defined as the microorganisms that reside in or on the human body, such as bacteria, viruses, fungi, and protozoa, and their genomes. The human microbiome participates in the modulation...

    Authors: Zi-Kun Yu, Rui-Ling Xie, Rui You, You-Ping Liu, Xu-Yin Chen, Ming-Yuan Chen and Pei-Yu Huang
    Citation: BMC Cancer 2021 21:934
    Content type: Review Published on:

  16. Smac/Diablo is a recently identified protein that is released from mitochondria after apoptotic stimuli. It binds IAPs, allowing caspase activation and cell death. In view of its activity it might participate ...

    Authors: Magali Espinosa, David Cantu, Carlos M Lopez, Jaime G De la Garza, Vilma A Maldonado and Jorge Melendez-Zajgla
    Citation: BMC Cancer 2004 4:84
    Content type: Research article Published on:

  17. Better methods to predict prognosis can play a supplementary role in administering individualized treatment for breast cancer patients. Altered expressions of PTHrP and TGF-β have been observed in various type...

    Authors: Cheng Xu, Zhengyuan Wang, Rongrong Cui, Hongyu He, Xiaoyan Lin, Yuan Sheng and Hongwei Zhang
    Citation: BMC Cancer 2015 15:925
    Content type: Research article Published on:

  18. Gastric cancer is a fatal gastrointestinal cancer with high morbidity and poor prognosis. The dismal 5-year survival rate warrants reliable biomarkers to assess and improve the prognosis of gastric cancer. Dis...

    Authors: Nannan Liu, Yun Wu, Weipeng Cheng, Yuxuan Wu, Liguo Wang and Liwei Zhuang
    Citation: BMC Cancer 2021 21:460
    Content type: Research Published on:

  19. Little is known about treatment expectations of patients with spinal metastases undergoing radiotherapy and/or surgery. Assuming that patients with spinal metastases share characteristics with patients who had...

    Authors: R. Gal, D. Oostinga, H. Wessels, J. J. Verlaan, R. Charest-Morin, C. G. Fisher, H. M. Verkooijen and A. L. Versteeg
    Citation: BMC Cancer 2020 20:1212
    Content type: Research article Published on:

  20. Bladder cancer (BC) is one of the most common malignancies globally. Early diagnosis of it can significantly improve patients’ survival and quality of life. Urinary exosomes (UEs)-derived miRNAs might be a pro...

    Authors: Hao Lin, Xiaojun Shi, Haoran Li, Jialiang Hui, Ruiyu Liu, Zihao Chen, Yuwen Lu and Wanlong Tan
    Citation: BMC Cancer 2021 21:1293
    Content type: Research Published on:

  21. Chronic inflammation is considered as a hallmark of gastric cancer (GC) and plays a critical role in GC progression and metastasis. This study aimed to explore the prognostic values of preoperative fibrinogen-...

    Authors: Shuli Tang, Lin Lin, Jianan Cheng, Juan Zhao, Qijia Xuan, Jiayue Shao, Yang Zhou and Yanqiao Zhang
    Citation: BMC Cancer 2020 20:382
    Content type: Research article Published on:

  22. Metabolic reprogramming is one of hallmarks of cancer progression and is of great importance for the tumor microenvironment (TME). As an abundant metabolite, lactate has been found to play a critical role in c...

    Authors: Rui Shi, Haojia Li, Sitian Wei, Zhicheng Yu, Jun Zhang, Qi Zhang, Ting Zhou, Yuwei Yao, Qian Zhang, Tangansu Zhang and Hongbo Wang
    Citation: BMC Cancer 2023 23:491
    Content type: Research Published on:

  23. Gastric cancer is one of the deadliest cancers, currently available therapies have limited success. Cancer-associated fibroblasts (CAFs) are pivotal cells in the stroma of gastric tumors posing a great risk fo...

    Authors: Cemre Ucaryilmaz Metin and Gulnihal Ozcan
    Citation: BMC Cancer 2022 22:692
    Content type: Research Published on:

  24. Single arm phase 1 and 2 studies on Crizotinib in ALK-positive patients so far have shown rapid and durable responses. Spontaneous pneumothoraces as a result of response to anti-cancer therapy are rare in onco...

    Authors: Spyridon Gennatas, Susana J Stanway, Robert Thomas, Toon Min, Riyaz Shah, Mary ER O’Brien and Sanjay Popat
    Citation: BMC Cancer 2013 13:207
    Content type: Case report Published on:

  25. Brain metastasis (BM) of colorectal cancer is a disease with a poor prognosis of only a few months survival. However, it is difficult to estimate the individual prognosis of each patient due to the lack of def...

    Authors: Caroline Sander, Clara Frydrychowicz, Gordian Prasse, Sabine Taubenheim, Felix Arlt, Jürgen Meixensberger and Michael Karl Fehrenbach
    Citation: BMC Cancer 2022 22:336
    Content type: Research Published on:

  26. To investigate the prognostic value of derived neutrophil to lymphocyte ratio (dNLR) and lactate dehydrogenase (LDH) in patients with advanced HER2 positive breast cancer treated with trastuzumab emtansine.

    Authors: Liru Li, Lin Ai, Lin Jia, Lei Zhang, Boya Lei and Qingyuan Zhang
    Citation: BMC Cancer 2022 22:29
    Content type: Research Published on:

  27. Although numerous studies have investigated the clinicopathologic and prognostic relevance of mucinous adenocarcinoma (MAC) and signet-ring cell carcinoma (SRCC) compared with classic adenocarcinoma (CA), litt...

    Authors: Hui Sheng, Xiaoli Wei, Minjie Mao, Jincan He, Tianqi Luo, Shilin Lu, Liye Zhou, Zhixin Huang and Anli Yang
    Citation: BMC Cancer 2019 19:1071
    Content type: Research article Published on:

  28. Cancer stem cells (CSCs) are notorious for their capacity of tumor progression, metastasis or resistance to chemo-radiotherapy. However, the undisputed role of cancer stem marker, CD133, in colorectal cancers ...

    Authors: Khalilullah Mia-Jan, So Young Jung, Ik-Yong Kim, Sung Soo Oh, EunHee Choi, Sei Jin Chang, Tae Young Kang and Mee-Yon Cho
    Citation: BMC Cancer 2013 13:166
    Content type: Research article Published on:

  29. CD276 (also known as B7-H3) is one of the most important immune checkpoints of the CD28 and B7 superfamily, and its abnormal expression is closely associated with various types of cancer. It has been shown that C...

    Authors: Lirui Dai, Xuyang Guo, Zhe Xing, Yiran Tao, Wulong Liang, Zimin Shi, Weihua Hu, Shaolong Zhou and Xinjun Wang
    Citation: BMC Cancer 2023 23:102
    Content type: Research Published on:

  30. The BRCA mutation (BRCAm) in males has been reported to confer a higher risk for the development of various tumors. However, little is known about its clinicopathologic features and prognostic implications.

    Authors: Peng Sun, Yue Li, Xue Chao, Jibin Li, Rongzhen Luo, Mei Li and Jiehua He
    Citation: BMC Cancer 2020 20:994
    Content type: Research article Published on:

  31. As a molecule controlling the assembly of central spindles and recruitment of midzone component, coiled-coil domain-containing protein 69 (CCDC69) plays an important role in multiple cancers. Currently, the re...

    Authors: Zhen Wang, Huiyang Ren, Guolian Zhu, Lei Zhang, Hongyi Cao and Bo Chen
    Citation: BMC Cancer 2023 23:974
    Content type: Research Published on:

  32. Breast cancer remains a significant health challenge worldwide, necessitating the identification of reliable biomarkers for early detection, accurate prognosis, and targeted therapy.

    Authors: Ali Golestan, Ahmad Tahmasebi, Nafiseh Maghsoodi, Seyed Nooreddin Faraji, Cambyz Irajie and Amin Ramezani
    Citation: BMC Cancer 2024 24:155
    Content type: Research Published on:

  33. Accurate diagnosis of early lung cancer from small pulmonary nodules (SPN) is challenging in clinical setting. We aimed to develop a radiomic nomogram to differentiate lung adenocarcinoma from benign SPN.

    Authors: Qin Liu, Yan Huang, Huai Chen, Yanwen Liu, Ruihong Liang and Qingsi Zeng
    Citation: BMC Cancer 2020 20:533
    Content type: Research article Published on:

  35. To explore challenges of liquid-based cytology (LBC) specimens for next-generation sequencing (NGS) in lung adenocarcinoma and evaluate the efficacy of targeted therapy.

    Authors: Xiaoyue Xiao, ZiHan Sun, Shuo Liang, Weihua Li, HuiQin Guo, Huan Zhao, LinLin Zhao, HaiYue Ma, Yue Sun, Cong Wang, XinXiang Chang and ZhiHui Zhang
    Citation: BMC Cancer 2024 24:749
    Content type: Research Published on:

  36. Colorectal cancer (CRC) is the fourth leading cause of cancer related deaths worldwide and prognosis in advanced tumor stage still remains poor. Since CK1 isoforms have been reported to be deregulated in sever...

    Authors: Julia Richter, Anna-Laura Kretz, Johannes Lemke, Michael Fauler, Jens-Uwe Werner, Stephan Paschke, Frank Leithäuser, Doris Henne-Bruns, Andreas Hillenbrand and Uwe Knippschild
    Citation: BMC Cancer 2018 18:140
    Content type: Research article Published on:

  37. Alternative polyadenylation (APA) is emerging as a crucial regulatory mechanism in bladder cancer (BC), while it remains elusive whether APA influences the tumor immune microenvironment (TIME) in BC. We identi...

    Authors: Ming Xiong, Wencheng Li, Longwang Wang, Liang Chen, Zhaohui Chen, Chengcheng Wei, Futian Zhang, Jiawei Chen, Gallina Kazobinka, Jun Zhao and Teng Hou
    Citation: BMC Cancer 2022 22:1026
    Content type: Research Published on:

  38. Anti-tumor effects of radiation therapy (RT) largely depend on host immune function. Adenosine with its strong immunosuppressive properties is an important immune checkpoint molecule.

    Authors: Hidenori Tsukui, Hisanaga Horie, Koji Koinuma, Hideyuki Ohzawa, Yasunaru Sakuma, Yoshinori Hosoya, Hironori Yamaguchi, Kotaro Yoshimura, Alan Kawarai Lefor, Naohiro Sata and Joji Kitayama
    Citation: BMC Cancer 2020 20:411
    Content type: Research article Published on:

  40. Late detection of hepatocellular carcinoma (HCC) results in an overall 5-year survival rate of less than 16%. Liquid biopsy (LB) assays based on detecting circulating tumor DNA (ctDNA) might provide an opportu...

    Authors: Van-Chu Nguyen, Trong Hieu Nguyen, Thanh Hai Phan, Thanh-Huong Thi Tran, Thu Thuy Thi Pham, Tan Dat Ho, Hue Hanh Thi Nguyen, Minh-Long Duong, Cao Minh Nguyen, Que-Tran Bui Nguyen, Hoai-Phuong Thi Bach, Van-Vu Kim, The-Anh Pham, Bao Toan Nguyen, Thanh Nhan Vo Nguyen, Le Anh Khoa Huynh…
    Citation: BMC Cancer 2023 23:233
    Content type: Research Published on:

  42. The focus of this study was to assess the impact of lymphovascular invasion (LVI) on both the recurrence of cancer and the long-term survival of Chinese patients with resectable gastric cancer (GC).

    Authors: Peng Li, Hao-Qiang He, Chong-Mei Zhu, Yi-Hong Ling, Wan-Ming Hu, Xin-Ke Zhang, Rong-Zhen Luo, Jing-Ping Yun, Dan Xie, Yuan-Fang Li and Mu-Yan Cai
    Citation: BMC Cancer 2015 15:370
    Content type: Research article Published on:

  44. The presence of comorbidity affects the care of cancer patients, many of whom are living with multiple comorbidities. The prevalence of cancer comorbidity, beyond summary metrics, is not well known. This study...

    Authors: Helen Fowler, Aurelien Belot, Libby Ellis, Camille Maringe, Miguel Angel Luque-Fernandez, Edmund Njeru Njagi, Neal Navani, Diana Sarfati and Bernard Rachet
    Citation: BMC Cancer 2020 20:2
    Content type: Research article Published on:

  45. MicroRNA-148b (miR-148b) has been detected in various types of tumors, and is generally viewed as a tumor suppressor. Our previous study found the decreased expression of miR-148b in human non small cell lung ...

    Authors: Lin Lu, Qiyao Liu, Peipei Wang, Yong Wu, Xia Liu, Chengyin Weng, Xisheng Fang, Baoxiu Li, Xiaofei Cao, Haibo Mao, Lina Wang, Mingmei Guan, Wei Wang and Guolong Liu
    Citation: BMC Cancer 2019 19:209
    Content type: Research article Published on:

  46. ADP-ribosylation factor-like protein 4 C (ARL4C) is a member of the ARF small GTP-binding protein subfamily. The ARL4C gene is highly expressed in colorectal cancer (CRC). ARL4C protein promotes cell motility, in...

    Authors: Ryo Kanai, Takeshi Uehara, Takahiro Yoshizawa, Masato Kamakura, Tomoyuki Nakajima, Yasuhiro Kinugawa, Mai Iwaya, Shiho Asaka, Masato Kitazawa, Tadanobu Nagaya and Hiroyoshi Ota
    Citation: BMC Cancer 2023 23:478
    Content type: Research Published on:

  47. In this retrospective study, data from patients listed in the Korea Central Cancer Registry during 1993–2014 were analysed, to investigate the incidence and survival of second primary cancers (SPCs) after a di...

    Authors: Myong Cheol Lim, Young-Joo Won, Jiwon Lim, Tahereh Salehi, Chong Woo Yoo and Robert E. Bristow
    Citation: BMC Cancer 2018 18:800
    Content type: Research article Published on:

  48. Function of the immune system is correlated with the prognosis of the tumor. The effect of immune microenvironment on esophageal cancer (EC) development has not been fully investigated.

    Authors: Zhi Zhang, Cheng Chen, Ying Fang, Sheng Li, Xiaohua Wang, Lei Sun, Guoren Zhou and Jinjun Ye
    Citation: BMC Cancer 2021 21:113
    Content type: Research article Published on:

  49. Hyaluronan is a large extracellular matrix molecule involved in several biological processes such as proliferation, migration and invasion. In many cancers, hyaluronan synthesis is altered, which implicates di...

    Authors: Mari Poukka, Andrey Bykachev, Hanna Siiskonen, Kristiina Tyynelä-Korhonen, Päivi Auvinen, Sanna Pasonen-Seppänen and Reijo Sironen
    Citation: BMC Cancer 2016 16:313
    Content type: Research article Published on:

  50. Coagulation and fibrinolysis activation is frequently observed in cancer patients, and the tumors in these cases are thought to be associated with a higher risk of invasion, metastasis, and worse long-term out...

    Authors: Yi-Jun Shu, Hao Weng, Run-Fa Bao, Xiang-Song Wu, Qian Ding, Yang Cao, Xu-An Wang, Fei Zhang, Shan-Shan Xiang, Huai-Feng Li, Mao-Lan Li, Jia-Sheng Mu, Wen-Guang Wu and Ying-Bin Liu
    Citation: BMC Cancer 2014 14:566
    Content type: Research article Published on:

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