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  1. Tumor necrosis factor receptor-associated factor 3 (TRAF3) has specific regulatory effects on a wide range of diseases, including tumors. However, the effect and mechanism of TRAF3 on lung adenocarcinoma (LUAD...

    Authors: Wangjia Wang, Shiqi Wang, Min Wang, Yamei Ma, Wanting Hu, Binsha Wu, Chichi Li and Dan Zhang
    Citation: BMC Cancer 2023 23:942
    Content type: Research Published on:

  2. Inflammatory, immune, and nutritional status are key factors in obstructive colorectal cancer (OCRC). This study aims to investigate the value of modified Naples prognostic score (M-NPS) in evaluating OCRC pro...

    Authors: Junnan Gu, Shenghe Deng, Zhenxing Jiang, Fuwei Mao, Yifan Xue, Le Qin, Jianguo Shi, Jia Yang, Huili Li, Jie Yu, Ke Liu, Ke Wu, Yinghao Cao and Kailin Cai
    Citation: BMC Cancer 2023 23:941
    Content type: Research Published on:

  3. This study aimed to identify patients with upper urinary tract urothelial carcinoma (UTUC) having potential Lynch syndrome (pLS) by immunohistochemistry (IHC) of DNA mismatch repair gene-related proteins (MMRP...

    Authors: Kenji Tanabe, Yasukazu Nakanishi, Naoya Okubo, Shunya Matsumoto, Yosuke Umino, Madoka Kataoka, Shugo Yajima, Teruhiko Yoshida, Saori Miyazaki, Takeshi Kuwata, Genichiro Ishii, Reiko Watanabe and Hitoshi Masuda
    Citation: BMC Cancer 2023 23:940
    Content type: Research Published on:

  4. Extracellular vesicles (EVs) hold promise for improving our understanding of radiotherapy response in glioblastoma due to their role in intercellular communication within the tumour microenvironment (TME). How...

    Authors: Stephen David Robinson, Mark Samuels, William Jones, Duncan Gilbert, Giles Critchley and Georgios Giamas
    Citation: BMC Cancer 2023 23:939
    Content type: Research Published on:

  5. Egypt has the greatest prevalence of hepatitis C worldwide according to the WHO reports, accounting for 13% of the global HCV infections. HCV is a substantial precursor for fibrosis, cirrhosis, and hepatocellu...

    Authors: Kholoud Baraka, Rania R. Abozahra, Eman Badr and Sarah M. Abdelhamid
    Citation: BMC Cancer 2023 23:938
    Content type: Research Published on:

  6. Gliomas are the most common malignant brain tumors, with powerful invasiveness and an undesirable prognosis. Actin related protein 2/3 complex subunit 5 (ARPC5) encodes a component of the Arp2/3 protein comple...

    Authors: Yue Ming, Chunyuan Luo, Beihong Ji and Jian Cheng
    Citation: BMC Cancer 2023 23:937
    Content type: Research Published on:

  8. Leucine-rich pentatricopeptide repeat containing (LRPPRC) is a potential oncogene in multiple tumor types, including lung adenocarcinoma, esophageal squamous cell carcinoma and gastric cancer. LRPPRC exerts it...

    Authors: Ziyi Zhao, Yingwei Sun, Jing Tang, Yuting Yang and Xiaochao Xu
    Citation: BMC Cancer 2023 23:935
    Content type: Research Published on:

  9. Recent studies have indicated that epigenetic alterations contribute significantly to lymphoma pathogenesis. A type of epigenetic regulation known as histone acetylation plays a crucial role in transcriptional...

    Authors: Zhuoya Yu, Mengfei Ding, Yiqing Cai, Tiange Lu, Xiaomin Chen, Xiangxiang Zhou and Xin Wang
    Citation: BMC Cancer 2023 23:934
    Content type: Research Published on:

  10. Venous thromboembolism (VTE) is a common postoperative complication in patients undergoing surgery for gastric cancer (GC). Although VTE incidence may vary among cancers, guidelines rarely stratify preventive ...

    Authors: Lin Xiang, Shuai Jin, Yang Yu, Dengfeng Wang and Hao Chen
    Citation: BMC Cancer 2023 23:933
    Content type: Research Published on:

  11. Dietary advanced glycation end products (AGEs) can play an important role in increasing inflammatory factors and oxidative stress as risk factors for cancers. In the present study, we aimed to assess the relat...

    Authors: Mitra Kazemi Jahromi, Asal Neshatbini Tehrani, Hossein Farhadnejad, Hadi Emamat, Hamid Ahmadirad, Farshad Teymoori, Zeinab Heidari, Niloufar Saber, Bahram Rashidkhani and Parvin Mirmiran
    Citation: BMC Cancer 2023 23:932
    Content type: Research Published on:

  12. Detecting a health-promoting lifestyle in colorectal cancer (CRC) survivors is of paramount importance to manage disease complications, prevent their recurrence, and enhance survival; however, no specialized t...

    Authors: Elahe Ramezanzade Tabriz, Monir Ramezani, Abbas Heydari, Seyed Amir Aledavood and Jamshid Jamali
    Citation: BMC Cancer 2023 23:931
    Content type: Research Published on:

  13. Nonsecretory multiple myeloma (NSMM) is a rare type of multiple myeloma (MM). Few studies have described the clinical features and outcomes of NSMM in novel agents. Additionally, the prognostic characteristics...

    Authors: Hailu Sun, Aijun Liu, Lihong Liu, Wei Wang, Zhen Cai, Hua Yan, Lijuan Chen, Guangxun Gao, Fang Wang, Aijun Liao, Bing Chen, Jia Feng, Juan Li, Dong-Ping Huang, Da Gao, Qi-Ke Zhang…
    Citation: BMC Cancer 2023 23:930
    Content type: Research Published on:

  14. Immunoglobulin lambda (Igλ) has been reported to be expressed in many normal and tumor tissues and cells. However, the function and clinical significance of tumor-derived Igλ remain unclear.

    Authors: Juping Wang, Jiangni Huang, Hao Ding, Jing Ma, Haohua Zhong, Fanlu Wang, Yupeng Chen and Hui Peng
    Citation: BMC Cancer 2023 23:929
    Content type: Research Published on:

  15. Gastric cancer (GC) is one of the malignant tumors with the highest mortality worldwide. Our previous studies have revealed that LINC00691 is up-regulated in serum of GC patients as a novel potential biomarker...

    Authors: Bin Xia, Xiuyu Gu, Tingting Xu, Meina Yan, Lan Huang, Chun Jiang, Meifen Li, Guanghua Zhai, Guoping Zhang, Jian Wu, Yu Zhou, Chunrong Sun and Wei Liang
    Citation: BMC Cancer 2023 23:928
    Content type: Research Published on:

  16. The impact of prostate radiotherapy on patient-reported health-related quality of life (HRQoL) significantly influences the outcomes of metastatic prostate cancer. We measured and compared HRQoL of metastatic ...

    Authors: Heba Maged Ayoub, Maha Lotfy Zamzam, Eman Essam Elsemary, Ihab Mohamed Hassanin and Fifi Mostafa Elsayed
    Citation: BMC Cancer 2023 23:927
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2024 24:419

  17. Tumor cell-monocyte interactions play crucial roles in shaping up the pro-tumorigenic phenotype and functional output of tumor-associated macrophages. Within the tumor microenvironment, such heterotypic cell–c...

    Authors: Asif Amin, Aabid Mustafa Koul, Umer Majeed Wani, Faizah Farooq, Basit Amin, Zubair Wani, Asif Lone, Ayub Qadri and Raies A. Qadri
    Citation: BMC Cancer 2023 23:926
    Content type: Research Published on:

  18. The interferon-induced protein known as guanylate-binding protein 2 (GBP2) has been linked to multiple different cancer types as an oncogenic gene. Although the role of GBP2 in cancer has been preliminarily ex...

    Authors: Yunfei Wang, Jiadong Pan, Fangmei An, Ke Chen, Jiawei Chen, He Nie, Yanping Zhu, Zhengtao Qian and Qiang Zhan
    Citation: BMC Cancer 2023 23:925
    Content type: Research Published on:

  19. Eyelid skin cancers are the most prevalent ophthalmic malignancies. This study aimed to evaluate the association of the Human Development Index (HDI) and lifestyle risk factors with eyelid skin cancers in Iran.

    Authors: Sare Safi, Mohadese Ahmadzade, Saeed Karimi, Mohammad Esmaeil Akbari, Hamidreza Rouientan, Mohammad Abolhosseini, Mozhgan Rezaei Kanavi and Zahra Khorrami
    Citation: BMC Cancer 2023 23:924
    Content type: Research Published on:

  20. Ultra-hypofractionated regimens for definitive prostate cancer (PCa) radiotherapy are increasingly utilized due in part to promising safety and efficacy data complemented by greater patient convenience from a ...

    Authors: Sydney Wolfe, Marshall A. Diven, Ariel E. Marciscano, Xi Kathy Zhou, A. U. Kishan, M. L. Steinberg, Joseph A. Miccio, Philip Camilleri and Himanshu Nagar
    Citation: BMC Cancer 2023 23:923
    Content type: Study Protocol Published on:

  21. Trastuzumab is the only approved target agent for the first-line treatment of human epidermal growth factor receptor-2 (HER-2) positive gastric cancer; however, trastuzumab resistance is a major problem in cli...

    Authors: Yuna Kim, Yoo Jin Bae, Jie-Hyun Kim, Hyunki Kim, Su-Jin Shin, Da Hyun Jung and Hyojin Park
    Citation: BMC Cancer 2023 23:922
    Content type: Research Published on:

  22. Phospholipase C Delta 3 (PLCD3) is a member of phospholipase C(PLC) Protein and PLCD3 protein plays a prominent role in many cancers. However, little is known about the role of PLCD3 in esophageal squamous cel...

    Authors: Mengmeng Wang, Mingjun Gao, Yong Chen, Jun Wu, Xiaolin Wang and Yusheng Shu
    Citation: BMC Cancer 2023 23:921
    Content type: Research Published on:

  23. Despite major advances in cancer therapeutics, the therapeutic options of Lung Squamous Cell Carcinoma (LSCC)-specific remain limited. Furthermore, the current staging system is imperfect for defining a progno...

    Authors: Chen-ye Shao, Jing Luo, Sheng Ju, Chu-ling Li, Cheng Ding, Jun Chen, Xiao-long Liu, Jun Zhao and Li-qin Yang
    Citation: BMC Cancer 2023 23:920
    Content type: Research Published on:

  24. This retrospective analysis of data from clinical trials in metastatic urothelial carcinoma (mUC) was conducted to determine baseline patient characteristics associated with long-term survival (LTS) following ...

    Authors: Marie Alt, Carlos Stecca, Yian Lin, Gbenga Kazeem, Erik T. Goluboff and Srikala S. Sridhar
    Citation: BMC Cancer 2023 23:919
    Content type: Research Published on:

  25. Understanding how patient-reported experiences of care and overall rating of care vary among patients with different characteristics is useful to help interpret results from patient experience surveys and desi...

    Authors: Chantal Arditi, Manuela Eicher, Julien Junod and Isabelle Peytremann-Bridevaux
    Citation: BMC Cancer 2023 23:918
    Content type: Research Published on:

  26. Although research has advanced the field of oncologic geriatrics with survivors to assess their cancer-related needs and devise patient-centered interventions, most of that research has excluded rural populati...

    Authors: Evelyn Arana-Chicas, Laura M. Hincapie Prisco, Saloni Sharma, Fiona Stauffer, Martha McGee, Serge Dauphin, Makiko Ban-Hoefen, Jaime Navarette, Jason Zittel, Ana Paula Cupertino, Allison Magnuson, Karen M. Mustian and Supriya G. Mohile
    Citation: BMC Cancer 2023 23:917
    Content type: Research Published on:

  27. Concomitant diseases often occur in cancer patients and are important in decision-making regarding treatments. However, information regarding the prognostic relevance of comorbidities for mortality risk is sti...

    Authors: Ju Wu, Simiao Tian, Jian Xu, Nan Cheng, Xi Chen, Jiajun Yin and Zhequn Nie
    Citation: BMC Cancer 2023 23:916
    Content type: Research Published on:

  28. Whether serum lactate dehydrogenase-to-albumin ratio (LAR) influenced the outcomes of colorectal cancer (CRC) patients after radical surgery remained unclear. Therefore, this study sought to examine how LAR in...

    Authors: Xin-Peng Shu, Ying-Chun Xiang, Fei Liu, Yong Cheng, Wei Zhang and Dong Peng
    Citation: BMC Cancer 2023 23:915
    Content type: Research Published on:

  30. The negative effects of the novel coronavirus disease 2019 (COVID-19) pandemic on patients with gastric cancer are poorly understood. This study was designed to compare the short-term and long-term outcomes of...

    Authors: Yong Sun, Chao Chen, Lei Hou and Enhong Zhao
    Citation: BMC Cancer 2023 23:913
    Content type: Research Published on:

  31. Long non-coding RNAs (lncRNAs) play important roles in many pathophysiological processes, including cancer progression. Namely, lncRNA Receptor-tyrosine-kinase-like orphan receptor-1 antisense 1 (ROR1-AS1) is ...

    Authors: Xueliang Li, Zhaowei Sun, Li Wang, Qinlei Wang, Maobing Wang, Jingyun Guo, Haoran Li, MenShou Chen, Guanghua Cao, Yanan Yu, Haochen Zhong, Hao Zou, Kai Ma, Bingyuan Zhang, Guolei Wang and Yujie Feng
    Citation: BMC Cancer 2023 23:912
    Content type: Research Published on:

  33. The goal of therapy for many patients with advanced stage malignancies, including those with metastatic gastric and esophageal cancers, is to extend overall survival while also maintaining quality of life. Aft...

    Authors: Xiaoyuan Ma, Eric Pierce, Harsh Anand, Natalie Aviles, Paul Kunk and Negin Alemazkoor
    Citation: BMC Cancer 2023 23:910
    Content type: Research Published on:

  35. Well-differentiated (WD) neuroendocrine tumors (NETs) are a group of rare neoplasms with limited therapeutic options. Cabozantinib is an inhibitor of multiple tyrosine kinases with a pivotal role in NET pathog...

    Authors: Francesca Corti, Maria Pia Brizzi, Vito Amoroso, Dario Giuffrida, Francesco Panzuto, Davide Campana, Natalie Prinzi, Massimo Milione, Tommaso Cascella, Carlo Spreafico, Giovanni Randon, Simone Oldani, Rita Leporati, Giulia Scotto, Iolanda Pulice, Benedetta Lombardi Stocchetti…
    Citation: BMC Cancer 2023 23:908
    Content type: Study protocol Published on:

  36. Heterozygous isocitrate dehydrogenase (IDH) mutations occur in about half of conventional central bone chondrosarcomas (CCBC). Aim of this study was to assess the frequency and prognostic impact of IDH mutations ...

    Authors: Elisabetta Setola, S. Benini, A. Righi, G. Gamberi, E. Carretta, C. Ferrari, S. Avnet, E. Palmerini, G. Magagnoli, M. Gambarotti, P. L. Lollini, M. Cesari, S. Cocchi, A. Paioli, A. Longhi, K. Scotlandi…
    Citation: BMC Cancer 2023 23:907
    Content type: Research Published on:

  37. Hepatocellular carcinoma (HCC), the most common primary liver cancer, prevails mainly in males and has long been attributed to androgens and higher circumstantial levels of interleukin-6 (IL-6) produced by res...

    Authors: Yahong Xu, Yongjie Zhu, Zhenru Wu, Shengfu Li, Mingyang Shao, Qing Tao, Qing Xu, Yuwei Chen, Yuke Shu, Menglin Chen, Yongjie Zhou and Yujun Shi
    Citation: BMC Cancer 2023 23:906
    Content type: Research Published on:

  38. We aimed to evaluate the clinical efficacy and prognostic significance of intensity-modulated radiotherapy (IMRT)-based salvage concurrent chemoradiotherapy (CCRT) for patients with locoregional recurrence cer...

    Authors: Minjie Shan, Yuping Deng, Wen Zou, Shasha Fan, Yanlong Li, Xianling Liu and Jingjing Wang
    Citation: BMC Cancer 2023 23:905
    Content type: Research Published on:

  39. Cancer survival rates are increasing; however, studies on dyslipidemia as a comorbidity of cancer are limited. For efficient management of the disease burden, this study aimed to understand new-onset dyslipide...

    Authors: Yun Hwa Jung, IL Yun, Eun-Cheol Park and Sung-In Jang
    Citation: BMC Cancer 2023 23:904
    Content type: Research Published on:

  40. Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) is the standard treatment for pseudomyxoma peritonei (PMP). It can significantly prolong the survival of patients, but at the ...

    Authors: Rui Yang, Xin Zhao, Yu-Bin Fu, Yu-Lin Lin, Ru Ma, Yan-Dong Su, He-Liang Wu, Xin-Li Liang and Yan Li
    Citation: BMC Cancer 2023 23:903
    Content type: Research Published on:

  41. The ALTA-1L study compared brigatinib with crizotinib in untreated ALK-rearranged non-small cell lung cancer (NSCLC) patients, demonstrating the efficacy of brigatinib. Although the median progression-free surviv...

    Authors: Kazushige Wakuda, Hirotsugu Kenmotsu, Yuki Sato, Atsushi Nakamura, Hiroaki Akamatsu, Motoko Tachihara, Satoru Miura, Toshihide Yokoyama, Keita Mori, Kazuhiko Nakagawa and Nobuyuki Yamamoto
    Citation: BMC Cancer 2023 23:902
    Content type: Study Protocol Published on:

  42. The application of coagulation-related markers in laryngeal squamous cell carcinoma(LSCC) remains unclear. This study explored the prognostic role of coagulation markers in the progression and metastasis of LSCC.

    Authors: Qiongling Huang, Jing Chen, Yanjun Huang, Yu Xiong, Jiao Zhou, Yizheng Zhang, Ming Lu, Weipeng Hu, Feng Zheng and Chaohui Zheng
    Citation: BMC Cancer 2023 23:901
    Content type: Research Published on:

  43. Early-stage colorectal cancer had excellent outcomes after curative resection, typically. However, a perplexing survival paradox between stage II and stage III was noted. This paradox could be influenced by th...

    Authors: Yen-Lin Yu, Wen-Ko Tseng, Chun-Kai Liao, Chien-Yuh Yeh, Hong-Hwa Chen, Yu-Hsuan Liu, Yu-Wei Liaw and Chung-Wei Fan
    Citation: BMC Cancer 2023 23:900
    Content type: Research Published on:

  44. Studies have demonstrated that Sorting nexin 7 (SNX7) functions as an anti-apoptotic protein in liver tissue and plays a crucial role in the survival of hepatocytes during early embryonic development. However,...

    Authors: Jianlin Chen, Gan Gao, Yi Zhang, Peng Dai and Yi Huang
    Citation: BMC Cancer 2023 23:899
    Content type: Research Published on:

  45. Long non-coding RNAs play an important role in the development of colorectal cancer (CRC), while many CRC-related lncRNAs have not yet been identified.

    Authors: Ganglin Ren, Hongyan Li, Dan Hong, Fangyu Hu, Rongjia Jin, Shuang Wu, Wenhao Sun, Honglei Jin, Lingling Zhao, Xiaodong Zhang, Dongxiang Liu, Chuanshu Huang and Haishan Huang
    Citation: BMC Cancer 2023 23:898
    Content type: Research Published on:

  46. Lung adenocarcinoma (LUAD) is an extraordinarily malignant tumor, with rapidly increasing morbidity and poor prognosis. Immunotherapy has emerged as a hopeful therapeutic modality for lung adenocarcinoma. Furt...

    Authors: Qianhe Ren, Qifan Li, Chenye Shao, Pengpeng Zhang, Zhuangzhuang Hu, Jun Li, Wei Wang and Yue Yu
    Citation: BMC Cancer 2023 23:897
    Content type: Research Published on:

  47. The dense stroma of pancreatic ductal adenocarcinomas is a major barrier to drug delivery. To increase the local drug diffusion gradient, high doses of chemotherapeutic agent doxorubicin can be released from t...

    Authors: Laura Spiers, Michael Gray, Paul Lyon, Shivan Sivakumar, Noor Bekkali, Shaun Scott, Linda Collins, Robert Carlisle, Feng Wu, Mark Middleton and Constantin Coussios
    Citation: BMC Cancer 2023 23:896
    Content type: Study protocol Published on:

  48. Although a long-term goal of cancer therapy always has been the development of agents that selectively destroy cancer cells, more recent trends have been to seek secondary agents that sensitize cancer cells to...

    Authors: D. Alimbetov, B. Umbayev, A. Tsoy, D. Begimbetova, T. Davis, D. Kipling and Sh. Askarova
    Citation: BMC Cancer 2023 23:895
    Content type: Research Published on:

  49. The incidence of peripherally inserted central catheter (PICC)-related complications is higher in cancer patients than in noncancer patients. However, the pattern of specific complication occurrence over time ...

    Authors: Ruixia Liu, Huiqiong Xu, Lihui Pu, Xiaofeng Xie, Hongxiu Chen, Zhoupeng Wu, Huirong Chen and Xiaoxia Zhang
    Citation: BMC Cancer 2023 23:894
    Content type: Research Published on:

  50. Pancreatic cancer is a growing public health concern in China, and depicting it from different perspectives would provide a comprehensive understanding of its epidemiological characteristics.

    Authors: Yangyang Xu, Wei Liu, Zheng Long, Lijun Wang, Maigeng Zhou and Peng Yin
    Citation: BMC Cancer 2023 23:893
    Content type: Research Published on:

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