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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 20 of 79

  1. Pancreatic ductal adenocarcinoma (PDAC) is a malignancy characterized by challenging early diagnosis and poor prognosis. It is believed that coagulation has an impact on the tumor microenvironment of PDAC. The...

    Authors: Di Wang, Song-ping Cui, Qing Chen, Zhang-yong Ren, Shao-cheng Lyu, Xin Zhao and Ren Lang
    Citation: BMC Cancer 2023 23:601
    Content type: Research Published on:

  2. Small cell neuroendocrine carcinoma of the uterine cervix (SCNEC) is a rare cancer involving the human papilloma virus (HPV), and has few available treatments. The present work aimed to assess the feasibility ...

    Authors: Shi-Wen Zhang, Rong-Zhen Luo, Xiao-Ying Sun, Xia Yang, Hai-Xia Yang, Si-Ping Xiong and Li-Li Liu
    Citation: BMC Cancer 2021 21:332
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Cancer 2021 21:416

  3. Gefitinib, a small molecule tyrosine kinase inhibitor of the Epidermal Growth Factor Receptor (EGFR), has shown limited efficacy in the treatment of lung cancer. Recognized clinical predictors of response to this...

    Authors: Trevor J Pugh, Gwyn Bebb, Lorena Barclay, Margaret Sutcliffe, John Fee, Chris Salski, Robert O'Connor, Cheryl Ho, Nevin Murray, Barbara Melosky, John English, Jeurgen Vielkind, Doug Horsman, Janessa J Laskin and Marco A Marra
    Citation: BMC Cancer 2007 7:128
    Content type: Research article Published on:

  4. Chromosome mis-segregation caused by spindle assembly checkpoint (SAC) dysfunction during mitosis is an important pathogenic factor in cancer, and modulating SAC function has emerged as a potential novel thera...

    Authors: Han Lei, Kun Wang, Tongying Jiang, Jingjing Lu, Xue Dong, Feilong Wang, Qiang Li and Liming Zhao
    Citation: BMC Cancer 2020 20:957
    Content type: Research article Published on:

  5. Hepatocellular carcinoma (HCC) is one of the major causes of tumor death; thus, the identification of markers related to its diagnosis and prognosis is critical. Previous studies have revealed that epithelial-...

    Authors: Yuki Shimoda, Yasunari Ubukata, Tadashi Handa, Takehiko Yokobori, Takayoshi Watanabe, Dolgormaa Gantumur, Kei Hagiwara, Takahiro Yamanaka, Mariko Tsukagoshi, Takamichi Igarashi, Akira Watanabe, Norio Kubo, Kenichiro Araki, Norifumi Harimoto, Ayaka Katayama, Toshiaki Hikino…
    Citation: BMC Cancer 2018 18:597
    Content type: Research article Published on:

  6. As both life expectancy and cancer survival improve, the incidence of multiple primary cancer has augmented and is expected to further increase. This study describes for the first time the epidemiology of mult...

    Authors: Gilles Macq, Geert Silversmit, Freija Verdoodt and Liesbet Van Eycken
    Citation: BMC Cancer 2023 23:349
    Content type: Research Published on:

  8. Although the National Comprehensive Cancer Network (NCCN) Guidelines recommend CCRT+AC and IC + CCRT as level 2A evidence for treatment of the locoregionally advanced NPC (II-IVa), IC + CCRT+AC could also be a...

    Authors: Wei Liu, Bolong Yu, Yunfan Luo, Junzheng Li, Xiaofei Yuan, Shuting Wu, Bijun Liang, Zehong Lv, Yanfei Li, Xinyu Peng, Juan Lu, Xiaohong Peng and Xiong Liu
    Citation: BMC Cancer 2021 21:639
    Content type: Research article Published on:

  9. Few studies have focused on the impact of single-organ pulmonary metastases on progression-free survival and overall survival in patients with metastatic colorectal cancer. Recognizing differences in prognosis...

    Authors: Koshiro Fukuda, Hiroki Osumi, Koichiro Yoshino, Izuma Nakayama, Shota Fukuoka, Mariko Ogura, Takeru Wakatsuki, Akira Ooki, Daisuke Takahari, Keisho Chin, Kensei Yamaguchi and Eiji Shinozaki
    Citation: BMC Cancer 2023 23:634
    Content type: Research Published on:

  10. In real-time RT quantitative PCR (qPCR) the accuracy of normalized data is highly dependent on the reliability of the reference genes (RGs). Failure to use an appropriate control gene for normalization of qPCR...

    Authors: Silvia Saviozzi, Francesca Cordero, Marco Lo Iacono, Silvia Novello, Scagliotti V Giorgio and Raffaele A Calogero
    Citation: BMC Cancer 2006 6:200
    Content type: Research article Published on:

  11. We usually report five-year survival from population-based cancer registries in Japan; however these survival estimates may be pessimistic for cancer survivors, because many patients with unfavourable prognosi...

    Authors: Yuri Ito, Tomio Nakayama, Isao Miyashiro, Akiko Ioka and Hideaki Tsukuma
    Citation: BMC Cancer 2013 13:304
    Content type: Research article Published on:

  12. Drug resistance is a major cause of therapeutic failure that is often associated with elevated autophagy and apurinic/apyrimidinic endonuclease 1 (APE1) expression. Herein, we investigated the role of APE1 and...

    Authors: Shu-Ting Pan, Ji Zhou, Fang Yang, Shu-Feng Zhou and Tao Ren
    Citation: BMC Cancer 2020 20:634
    Content type: Research article Published on:

  13. Adjuvant chemotherapy (ACT) plays an important role in improving the survival of stage II-III colorectal cancer (CRC) patients after curative surgery. However, the prognostic role of irregular delay of ACT (ID...

    Authors: Yuanyuan Chen, Mingyue Xu, Qianwen Ye, Jia Xiang, Tianhui Xue, Tao Yang, Long Liu and Bing Yan
    Citation: BMC Cancer 2022 22:670
    Content type: Research Published on:

  14. Radiotherapy is an important treatment for lung cancer, mainly by triggering DNA double-strand breaks to induce cell death. Blocking DNA damage repair can increase the radiosensitivity of tumor cells. Recent s...

    Authors: Zhipeng Du, Fangxiao Zhang, Lei Liu, Hui Shen, Tingting Liu, Jing Jin, Nanxi Yu, Zhijie Wan, Hang Wang, Xuguang Hu, Yuanyuan Chen and Jianming Cai
    Citation: BMC Cancer 2023 23:130
    Content type: Research Published on:

  15. Cisplatin is the first-line chemotherapeutic drug for non-small cell lung cancer (NSCLC), and emerging evidences suggests that targeting circular RNAs (circRNAs) is an effective strategy to increase cisplatin-...

    Authors: Xiang Zhu, Jing Han, Huiyin Lan, Qingren Lin, Yuezhen Wang and Xiaojiang Sun
    Citation: BMC Cancer 2020 20:1190
    Content type: Research article Published on:

  16. NUP155 is reported to be correlated with tumor development. However, the role of NUP155 in tumor physiology and the tumor immune microenvironment (TIME) has not been previously examined. This study comprehensivel...

    Authors: Zi-qiong Wang, Zhi-xuan Wu, Zong-pan Wang, Jing-xia Bao, Hao-dong Wu, Di-yan Xu, Hong-feng Li, Yi-Yin Xu, Rong-xing Wu and Xuan-xuan Dai
    Citation: BMC Cancer 2024 24:353
    Content type: Research Published on:

  17. Crizotinib can target against mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK), which has been considered as a multi-targeted tyrosine kinase inhibitor (TKI). The objective of this stu...

    Authors: Rui-Lian Chen, Jun Zhao, Xu-Chao Zhang, Na-Na Lou, Hua-Jun Chen, Xue Yang, Jian Su, Zhi Xie, Qing Zhou, Hai-Yan Tu, Wen-Zhao Zhong, Hong-Hong Yan, Wei-Bang Guo, Yi-Long Wu and Jin-Ji Yang
    Citation: BMC Cancer 2018 18:1171
    Content type: Research article Published on:

  18. The purpose of the present study was to characterize the prevalence, associated factors, and to construct a nomogram for predicting bone metastasis (BM) with different histological types of lung cancer.

    Authors: Chao Zhang, Min Mao, Xu Guo, Ping Cui, Lianmin Zhang, Yao Xu, Lili Li, Xiuxin Han, Karl Peltzer, Shunbin Xiong, Vladimir P. Baklaushev, Xin Wang and Guowen Wang
    Citation: BMC Cancer 2019 19:238
    Content type: Research article Published on:

  19. The mTOR signaling pathway plays an important role in cancer. As a master regulator, the status of MTOR affects pathway activity and the efficacy of mTOR inhibitor therapy. However, little research has been perfo...

    Authors: Chenxing Wang, Batuer Aikemu, Yanfei Shao, Sen Zhang, Guang Yang, Hiju Hong, Ling Huang, Hongtao Jia, Xiao Yang, Minhua Zheng, Jing Sun and Jianwen Li
    Citation: BMC Cancer 2022 22:818
    Content type: Research article Published on:

  20. Adrenocortical carcinoma (ACC) is a rare malignant endocrine tumour. Due to a high tumour recurrence rate, the post-operative overall survival (OS) and disease-free survival (DFS) of ACCs is limited. Our resea...

    Authors: Jiayu Liang, Zhihong Liu, Xin Wei, Liang Zhou, Yongquan Tang, Chuan Zhou, Kan Wu, Fuxun Zhang, Fan Zhang, Yiping Lu and Yuchun Zhu
    Citation: BMC Cancer 2019 19:1165
    Content type: Research article Published on:

  21. Although epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) have become the standard care of patients with advanced EGFR-mutant non-small cell lung cancer (NSCLC), development of acquired ...

    Authors: Ren Zhao, Shun Zhou, Bing Xia, Cui-ying Zhang, Ping Hai, Hong Zhe and Yan-yang Wang
    Citation: BMC Cancer 2016 16:491
    Content type: Research article Published on:

  22. The immune system recognizes and destroys cancer cells. However, cancer cells develop mechanisms to avoid detection by expressing cell surface proteins. Specific tumour cell surface proteins (e.g. HLA-G, PD-L1...

    Authors: Astrid Louise Bjørn Bennedsen, Luyi Cai, Rune Petring Hasselager, Aysun Avci Özcan, Khadra Bashir Mohamed, Jens Ole Eriksen, Susanne Eiholm, Michael Bzorek, Anne-Marie Kanstrup Fiehn, Thomas Vauvert F. Hviid and Ismail Gögenur
    Citation: BMC Cancer 2022 22:62
    Content type: Research Published on:

  23. Breast cancer is the most common malignancy in women, and it is also the leading cause of death in female patients; the most common pathological type of BC is infiltrating duct carcinoma (IDC). Some nomograms ...

    Authors: Zhangheng Huang, Chuan Hu, Kewen Liu, Luolin Yuan, Yinglun Li, Chengliang Zhao and Chanchan Hu
    Citation: BMC Cancer 2020 20:1145
    Content type: Research article Published on:

  24. Immune checkpoint blockades (ICBs) are characterized by a durable clinical response and better tolerability in patients with a variety of advanced solid tumors. However, we not infrequently encounter patients ...

    Authors: Seo Ree Kim, Sang Hoon Chun, Joo Ri Kim, Sang-Yeob Kim, Jun Young Seo, Chan Kwon Jung, Bo-Mi Gil, Jeong-Oh Kim, Yoon Ho Ko, In Sook Woo, Byoung Yong Shim, Sook-Hee Hong and Jin Hyoung Kang
    Citation: BMC Cancer 2021 21:19
    Content type: Research article Published on:

  25. Non-small cell lung cancer (NSCLC) remains a huge health burden for human health and life worldwide. Our study here was to illuminate the relevance of microRNA-130a-5p (miR-130a-5p) on growth and epithelial me...

    Authors: Fang Ma, Yangchun Xie, Yiyu Lei, Zengshuyu Kuang and Xianling Liu
    Citation: BMC Cancer 2020 20:580
    Content type: Research article Published on:

  26. We report on the results of a phase II clinical trial of Panagen (tablet form of fragmented human DNA preparation) in breast cancer patients (placebo group n = 23, Panagen n = 57). Panagen was administered as an ...

    Authors: Anastasia S. Proskurina, Tatiana S. Gvozdeva, Ekaterina A. Potter, Evgenia V. Dolgova, Konstantin E. Orishchenko, Valeriy P. Nikolin, Nelly A. Popova, Sergey V. Sidorov, Elena R. Chernykh, Alexandr A. Ostanin, Olga Y. Leplina, Victoria V. Dvornichenko, Dmitriy M. Ponomarenko, Galina S. Soldatova, Nikolay A. Varaksin, Tatiana G. Ryabicheva…
    Citation: BMC Cancer 2016 16:651
    Content type: Research article Published on:

  28. Non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutation often obtain de novo resistance or develop secondary resistance to EGFR tyrosine kinase inhibitors (EGFR-TKIs), wh...

    Authors: Yaya Yu, Zhenzhen Xiao, Chenjing Lei, Changju Ma, Lina Ding, Qing Tang, Yihan He, Yadong Chen, Xuesong Chang, Yanjuan Zhu and Haibo Zhang
    Citation: BMC Cancer 2023 23:732
    Content type: Research Published on:

  29. The overall prognosis of non-small cell lung cancer (NSCLC) is poor, and currently only patients with localized disease are potentially curable. Therefore, preferably non-invasively determined biomarkers that ...

    Authors: Dijana Djureinovic, Victor Pontén, Per Landelius, Sahar Al Sayegh, Kai Kappert, Masood Kamali-Moghaddam, Patrick Micke and Elisabeth Ståhle
    Citation: BMC Cancer 2019 19:741
    Content type: Research article Published on:

  30. Modulation of DNA damage repair in lung squamous cell carcinoma (LUSC) can result in the generation of neoantigens and heightened immunogenicity. Therefore, understanding DNA damage repair mechanisms holds sig...

    Authors: Lu Xia, Hexin Lin, Huifen Cao and Jiabian Lian
    Citation: BMC Cancer 2024 24:561
    Content type: Research Published on:

  31. Preoperative prediction of International Federation of Gynecology and Obstetrics (FIGO) stage in patients with epithelial ovarian cancer (EOC) is crucial for determining appropriate treatment strategy. This st...

    Authors: Yinping Leng, Ao Kan, Xiwen Wang, Xiaofen Li, Xuan Xiao, Yu Wang, Lan Liu and Lianggeng Gong
    Citation: BMC Cancer 2024 24:307
    Content type: Research Published on:

  32. Immunotherapy has become a new therapy for advanced hepatocellular carcinoma (HCC); however, its treatment results are considerably different. CD4+ T cells (CD4+) are the key to immunotherapy, but patients wit...

    Authors: Yong Zhao, Ling Xiang Kong, Feng Shi Feng, Jiayin Yang and Guo Wei
    Citation: BMC Cancer 2022 22:311
    Content type: Research Published on:

  33. Bronchoscopy is a common procedure used for evaluation of suspicious lung nodules, but the low diagnostic sensitivity of bronchoscopy often results in inconclusive results and delays in treatment. Percepta Gen...

    Authors: Marla K. Johnson, Shuyang Wu, Daniel G. Pankratz, Grazyna Fedorowicz, Jessica Anderson, Jie Ding, Mei Wong, Manqiu Cao, Joshua Babiarz, Lori Lofaro, P. Sean Walsh, Giulia C. Kennedy and Jing Huang
    Citation: BMC Cancer 2021 21:400
    Content type: Research article Published on:

  34. Identifying lymph node metastasis areas during surgery for early invasive lung adenocarcinoma remains challenging. The aim of this study was to develop a nomogram mathematical model before the end of surgery f...

    Authors: Mengchao Xue, Junjie Liu, Zhenyi Li, Ming Lu, Huiying Zhang, Wen Liu and Hui Tian
    Citation: BMC Cancer 2024 24:139
    Content type: Research Published on:

  35. Platinum-based chemotherapy has long been used in the treatment of a variety of cancers and functions by inducing DNA damage. ERCC1 and ERCC4 are involved in the removal of this damage and have previously been...

    Authors: David Hersi Smith, Ib Jarle Christensen, Niels Frank Jensen, Bo Markussen, Sven Müller, Hans Jørgen Nielsen, Nils Brünner and Kirsten Vang Nielsen
    Citation: BMC Cancer 2013 13:489
    Content type: Research article Published on:

  36. The epithelial-mesenchymal transition (EMT) plays an indispensable role in the development and progression of Endometrial cancer (EC). Nevertheless, little evidence is reported to uncover the functionality and...

    Authors: Yonghui Yu, Yiwen Zhang, Zhi Li, Yongshun Dong, Hongmei Huang, Binyao Yang, Eryong Zhao, Yongxiu Chen, Lei Yang, Jiachun Lu and Fuman Qiu
    Citation: BMC Cancer 2023 23:879
    Content type: Research Published on:

  37. The development of drug resistance is a major cause of cancer therapy failures. To inhibit drug resistance, multiple drugs are often treated together as a combinatorial therapy. In particular, synergistic drug...

    Authors: Sijiao Wang, Juliano Oliveira-Silveira, Gang Fang and Jungseog Kang
    Citation: BMC Cancer 2024 24:335
    Content type: Research Published on:

  39. Lung cancer remains the top contributor to cancer-related mortality worldwide. Long non-coding RNAs (lncRNAs) have been reported to participate in normal development and tumorigenesis. LncRNA nuclear enriched ...

    Authors: Wu Zhou, Xing Chen, Qinghua Hu, Xuliang Chen, Yingji Chen and Lingjin Huang
    Citation: BMC Cancer 2018 18:580
    Content type: Research article Published on:

  40. Gallbladder cancer (GBC) is likely to be diagnosed at progressive stages and shows a very poor prognosis. Combination therapy with gemcitabine and cisplatin (GEMCIS) has been widely used as first-line palliati...

    Authors: Min su You, Ji Kon Ryu, Young Hoon Choi, Jin Ho Choi, Gunn Huh, Woo Hyun Paik, Sang Hyub Lee and Yong-Tae Kim
    Citation: BMC Cancer 2019 19:10
    Content type: Research article Published on:

  41. With the improved knowledge of disease biology and the introduction of immune checkpoints, there has been significant progress in treating renal cell carcinoma (RCC) patients. Individual treatment will differ ...

    Authors: Chen Xu, Hui Zeng, Junli Fan, Wenjie Huang, Xiaosi Yu, Shiqi Li, Fubing Wang and Xinghua Long
    Citation: BMC Cancer 2022 22:264
    Content type: Research Published on:

  42. In this prospective non-interventional study, the effectiveness and tolerability of erlotinib in elderly patients with non-small-cell lung cancer (NSCLC) after ≥1 platinum-based chemotherapy were assessed.

    Authors: Wolfgang M. Brueckl, H. Jost Achenbach, Joachim H. Ficker and Wolfgang Schuette
    Citation: BMC Cancer 2018 18:333
    Content type: Research article Published on:

  43. It was demonstrated that long non-coding RNAs occupied an important position in tumor pathogenesis and progression. We have previously found that the metastasis-associated lung adenocarcinoma transcript 1 (MAL...

    Authors: Meng Zhuo, Cuncun Yuan, Ting Han, Jiujie Cui, Feng Jiao and Liwei Wang
    Citation: BMC Cancer 2018 18:1032
    Content type: Research article Published on:

  44. This study aims to evaluate the impact of colony stimulating factor-1 (CSF-1) expression on recurrence and survival of patients with clear-cell renal cell carcinoma (ccRCC) following surgery.

    Authors: Liu Yang, Qian Wu, Le Xu, Weijuan Zhang, Yu Zhu, Haiou Liu, Jiejie Xu and Jianxin Gu
    Citation: BMC Cancer 2015 15:67
    Content type: Research article Published on:

  45. Adenocarcinoma (ADC) and squamous cell carcinoma (SCC) are the most prevalent histological types among lung cancers. Distinguishing between these subtypes is critically important because they have different im...

    Authors: Arturo López Pineda, Henry Ato Ogoe, Jeya Balaji Balasubramanian, Claudia Rangel Escareño, Shyam Visweswaran, James Gordon Herman and Vanathi Gopalakrishnan
    Citation: BMC Cancer 2016 16:184
    Content type: Research article Published on:

  46. Interleukin (IL)-17 family is a group of six cytokines that plays a central role in inflammatory processes and participates in cancer progression. Interleukin-17A has been shown to have mainly a protumorigenic...

    Authors: Tiina Mikkola, Rabeia Almahmoudi, Tuula Salo and Ahmed Al-Samadi
    Citation: BMC Cancer 2022 22:54
    Content type: Research Published on:

  47. This study aimed to develop and validate an artificial intelligence radiopathological model using preoperative CT scans and postoperative hematoxylin and eosin (HE) stained slides to predict the pathological s...

    Authors: Yang Tan, Li-juan Feng, Ying-he Huang, Jia-wen Xue, Zhen-Bo Feng and Li-ling Long
    Citation: BMC Cancer 2024 24:368
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2024 24:469

  48. To evaluate whether quantification of lung GGN shape is useful in predicting pathological categorization of lung adenocarcinoma and guiding the clinic.

    Authors: Mingjie guo, Zhan Cao, Zhichao Huang, Shaowen Hu, Yafei Xiao, Qianzhou Ding, Yalong Liu, Xiaokang An, Xianjie Zheng, Shuanglin Zhang and Guoyu Zhang
    Citation: BMC Cancer 2024 24:35
    Content type: Research Published on:

  49. Tumour-associated lymphocytes (TALs) have been linked with good prognosis in several solid tumours. This study aimed to evaluate the prognostic significance of CD3, CD8 and CD20 positive lymphocytes in pancrea...

    Authors: Nilanjana Tewari, Abed M Zaitoun, Arvind Arora, Srinivasan Madhusudan, Mohammad Ilyas and Dileep N Lobo
    Citation: BMC Cancer 2013 13:436
    Content type: Research article Published on:

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