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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. Studies have demonstrated that Sorting nexin 7 (SNX7) functions as an anti-apoptotic protein in liver tissue and plays a crucial role in the survival of hepatocytes during early embryonic development. However,...

    Authors: Jianlin Chen, Gan Gao, Yi Zhang, Peng Dai and Yi Huang
    Citation: BMC Cancer 2023 23:899
    Content type: Research Published on:

  2. Hypoxia-inducible factor 1 (HIF-1) is a transcription factor, which plays a central role in biologic processes under hypoxic conditions, especially concerning tumour angiogenesis. HIF-1α is the relevant, oxyge...

    Authors: Thomas Fillies, Richard Werkmeister, Paul J van Diest, Burkhard Brandt, Ulrich Joos and Horst Buerger
    Citation: BMC Cancer 2005 5:84
    Content type: Research article Published on:

  3. There are differences in the pharmacoeconomics of Immune checkpoint blocking (ICB) therapies for the treatment of lung squamous cell carcinoma (LSCC). However, no corresponding review studies have fully discus...

    Authors: Minyu Cheng, Yanfei Shao, Li Li, Menglao Jiang and Zhouye Song
    Citation: BMC Cancer 2024 24:312
    Content type: Research Published on:

  4. Liver cancer is the third most deadly malignant tumor in the world with poor prognosis and lacks early diagnostic markers. It is urgent need to explore new biomarkers and prognostic factors. The oxysterol-bind...

    Authors: Kunpeng Tian, Yongling Ying, Jingjing Huang, Hao Wu, Chengyue Wei, Liang Li, Longjun Chen and Lichuan Wu
    Citation: BMC Cancer 2023 23:244
    Content type: Research Published on:

  5. Currently, no satisfactory biomarkers are available to screen for lung cancer. Surface-Enhanced Laser Desorption/ionization Time-of- Flight Mass Spectrometry ProteinChip system (SELDI-TOF-MS) is one of the cur...

    Authors: Shuan-ying Yang, Xue-yuan Xiao, Wang-gang Zhang, Li-juan Zhang, Wei Zhang, Bin Zhou, Guoan Chen and Da-cheng He
    Citation: BMC Cancer 2005 5:83
    Content type: Research article Published on:

  6. Basic research of gefitinib (Iressa, ZD1839) has demonstrated the combination effects of gefitinib and chemotherapy were sequence-dependent. To evaluate the efficacy of sequential administration of gefitinib f...

    Authors: Jian Ming Xu, Yu Han, Yue Min Li, Chuan Hua Zhao, Yan Wang and Angelo Paradiso
    Citation: BMC Cancer 2006 6:288
    Content type: Research article Published on:

  7. Glycolysis is a central metabolic pathway for tumor cells. However, the potential roles of glycolysis-related genes in renal cell carcinoma (RCC) have not been investigated.

    Authors: Fangshi Xu, Yibing Guan, Li Xue, Shanlong Huang, Ke Gao, Zhen Yang and Tie Chong
    Citation: BMC Cancer 2020 20:1207
    Content type: Research article Published on:

  8. Leptomeningeal metastasis (LM) is the most devastating complication of non-small cell lung cancer (NSCLC), and its incidence is increasing. There is currently no standard treatment for LM, and the efficacy of ...

    Authors: Tao Zhou, Shaofeng Zhu, Qiang Xiong, Jiongli Gan, Jianping Wei, Jing Cai and Anwen Liu
    Citation: BMC Cancer 2023 23:333
    Content type: Research Published on:

  9. Serum 25-hydroxyvitamin D [25(OH)D], the major circulating form of vitamin D used for evaluating the vitamin D status of patients, has been associated with survival in a variety of cancers with conflicting evi...

    Authors: Pankaj G. Vashi, Persis Edwin, Brenten Popiel and Digant Gupta
    Citation: BMC Cancer 2015 15:1012
    Content type: Research article Published on:

  10. Fermitin family member 1 (FERMT1) is highly expressed in many tumors and acts as an oncogene. Nonetheless, the precise function of FERMT1 in non-small cell lung cancer (NSCLC) has not been clearly elucidated.

    Authors: Bao Liu, Yan Feng, Naiying Xie, Yang Yang and Dameng Yang
    Citation: BMC Cancer 2024 24:58
    Content type: Research Published on:

  11. It is essential to have information on the disease burden of lung cancer at an individual level throughout the life; however, few such results have been reported. Thus, this study aimed to assess the lifetime ...

    Authors: Hae-Young Park, Jinseub Hwang, Do-Hyang Kim, Soo Min Jeon, Sun Ha Choi and Jin-Won Kwon
    Citation: BMC Cancer 2020 20:846
    Content type: Research article Published on:

  12. Although spread through air spaces (STAS) is a robust biomarker in surgically resected lung cancer, its application to biopsies is challenging. Moreover, limited resection is not an effective treatment for STA...

    Authors: Lanqing Cao, Meng Jia, Ping-Li Sun and Hongwen Gao
    Citation: BMC Cancer 2021 21:913
    Content type: Research article Published on:

  13. Neoadjuvant immune checkpoint inhibitors(ICIs) combined with chemotherapy can improve non-small cell lung cancer(NSCLC) patients' pathological responses and show promising improvements in survival. Chronic obs...

    Authors: Weigang Dong, Yan Yin, Shengnan Yang, Bin Liu, Xi Chen, Lina Wang, Yue Su, Yan Jiang, Dongsheng Shi, Daqiang Sun and Jianwen Qin
    Citation: BMC Cancer 2024 24:153
    Content type: Research Published on:

  14. Case-control studies of mass screening for lung cancer (LC) by chest x-rays (CXR) performed in the 1990s in scarcely defined Japanese target populations indicated significant mortality reductions, but these re...

    Authors: Lorenzo Dominioni, Nicola Rotolo, William Mantovani, Albino Poli, Salvatore Pisani, Valentina Conti, Massimo Paolucci, Fausto Sessa, Antonio Paddeu, Vincenzo D'Ambrosio and Andrea Imperatori
    Citation: BMC Cancer 2012 12:18
    Content type: Research article Published on:

  16. Despite the fact that tumor microenvironment (TME) and gene mutations are the main determinants of progression of the deadliest cancer in the world – lung cancer, their interrelations are not well understood. ...

    Authors: Alicja Rączkowska, Iwona Paśnik, Michał Kukiełka, Marcin Nicoś, Magdalena A. Budzinska, Tomasz Kucharczyk, Justyna Szumiło, Paweł Krawczyk, Nicola Crosetto and Ewa Szczurek
    Citation: BMC Cancer 2022 22:1001
    Content type: Research Published on:

  17. Patients from non-small cell lung cancer (NSCLC) controlled clinical trials do not always reflect real-world heterogeneous patient populations. We designed a study to describe the real-world patient characteri...

    Authors: Hozefa A. Divan, Marisa A. Bittoni, Ashok Krishna and David P. Carbone
    Citation: BMC Cancer 2024 24:424
    Content type: Research Published on:

  18. Tumor-specific growth factor (TSGF) is an immune-related factor that offers good performance in the clinical management of human cancers. However, the role of serum TSGF in esophageal squamous cell carcinoma (...

    Authors: Xiaoqin Xu, Weigang Wang, Baoguo Tian, Xiaofang Zhang, Yanfen Ji and Jiexian Jing
    Citation: BMC Cancer 2023 23:1067
    Content type: Research Published on:

  19. Targeting deubiquitinases (DUBs) has emerged as a promising avenue for anticancer drug development. However, the effect and mechanism of pan-DUB inhibitor EOAI on non-small cell lung cancer (NSCLC) remains to ...

    Authors: Yuanyuan Zheng, Longhao Wang, Xiaoyu Niu, Yongjun Guo, Jiuzhou Zhao, Lifeng Li and Jie Zhao
    Citation: BMC Cancer 2023 23:28
    Content type: Research Published on:

  20. We aimed to compare intra- and extracranial responses to immune checkpoint inhibitors (ICIs) in lung cancer with brain metastases (BM), and to explore tumor microenvironments of the brain and lungs focusing on...

    Authors: Ryul Kim, Bhumsuk Keam, Sehui Kim, Miso Kim, Se Hyun Kim, Jin Wook Kim, Yu Jung Kim, Tae Min Kim, Yoon Kyung Jeon, Dong-Wan Kim, Doo Hyun Chung, Jong Seok Lee and Dae Seog Heo
    Citation: BMC Cancer 2019 19:19
    Content type: Research article Published on:

  21. Lung cancer is the leading cause of cancer death worldwide and characterized by a poor prognosis. It has a major impact on the psychological wellbeing of patients and their partners. Recently, it has been show...

    Authors: Melanie PJ Schellekens, Desiree GM van den Hurk, Judith B Prins, Johan Molema, A Rogier T Donders, Willem H Woertman, Miep A van der Drift and Anne EM Speckens
    Citation: BMC Cancer 2014 14:3
    Content type: Study protocol Published on:

  22. Ferroptosis is a novel form of regulated cell death that is different from other forms, which has an important role in tumor growth inhibition. The purpose of this study was to construct and validate a prognos...

    Authors: Shuai Liu, Yu Yao, Mingyu Hou, Jingchang Mei, Lijiang Sun and Guiming Zhang
    Citation: BMC Cancer 2023 23:1079
    Content type: Research Published on:

  23. Papillary thyroid cancer (PTC) often presents as multifocal. However, the association of multifocality with poor prognosis remains controversial. The aim of this retrospective study was to identify the charact...

    Authors: Ning Qu, Ling Zhang, Qing-hai Ji, Yong-xue Zhu, Zhuo-ying Wang, Qiang Shen, Yu Wang and Duan-shu Li
    Citation: BMC Cancer 2014 14:914
    Content type: Research article Published on:

  24. There is absence of literature related to cough prevalence and its characteristics in lung cancer patients, with information deriving only from broader symptoms occurrence studies. The aims of this study were ...

    Authors: Amélie Harle, Alex Molassiotis, Oliver Buffin, Jack Burnham, Jaclyn Smith, Janelle Yorke and Fiona H. Blackhall
    Citation: BMC Cancer 2020 20:9
    Content type: Research article Published on:

  25. Stable disease (SD) has ambiguous clinical significance for patients according to the dominant Response Evaluation Criteria in Solid Tumours (RECIST). The primary aims of the study were: (1) to clarify the cli...

    Authors: Lijie He, Yuee Teng, Bo Jin, Mingfang Zhao, Ping Yu, Xuejun Hu, Jingdong Zhang, Songbai Li, Yaling Gao and Yunpeng Liu
    Citation: BMC Cancer 2010 10:681
    Content type: Research article Published on:

  26. Pembrolizumab has become an integral first line therapeutic agent for non-small cell lung cancer (NSCLC), but its potential predictive role in clinical and molecular characteristics remains to be clarified. Ac...

    Authors: Wenjie Liu, Gengwei Huo and Peng Chen
    Citation: BMC Cancer 2023 23:458
    Content type: Research Published on:

  27. The clinical features, survival outcomes and patterns of treatment failure of advanced non-small cell lung cancer (NSCLC) patients harboring distinct subtypes of EGFR mutations and receiving first-line EGFR ty...

    Authors: Ya Zeng, Tiantian Guo, Yue Zhou, Yang Zhao, Li Chu, Xiao Chu, Xi Yang, Jianjiao Ni and Zhengfei Zhu
    Citation: BMC Cancer 2022 22:198
    Content type: Research Published on:

  28. Lung adenocarcinoma (LUAD) is the most frequently diagnosed histological subtype of lung cancer. Our purpose was to explore molecular subtypes and core genes for LUAD using multi-omics analysis.

    Authors: Yue Zhao, Yakun Gao, Xiaodong Xu, Jiwu Zhou and He Wang
    Citation: BMC Cancer 2021 21:257
    Content type: Research article Published on:

  29. The occurrence of Chemotherapy-induced neutropenia (CIN) was reported to be a predictor of better survival in several cancers. The objective of our study is to evaluate the relationship between the timing of C...

    Authors: Yang Chen, YanRong Wang, Yan Shi and GuangHai Dai
    Citation: BMC Cancer 2017 17:242
    Content type: Research article Published on:

  30. Most cancer patients ultimately die from the consequences of distant metastases. As metastasis formation consumes energy mitochondria play an important role during this process as they are the most important c...

    Authors: Jil Weigelt, Mariam Petrosyan, Leticia Oliveira-Ferrer, Barbara Schmalfeldt, Catharina Bartmann, Johannes Dietl, Christine Stürken and Udo Schumacher
    Citation: BMC Cancer 2024 24:43
    Content type: Research Published on:

  31. Cancer Patient Pathways (CPPs) were introduced in 2000–2015 in several European countries, including Denmark, to reduce the time to diagnosis and treatment initiation and ultimately improve patient survival. Y...

    Authors: Henry Jensen, Marie Louise Tørring and Peter Vedsted
    Citation: BMC Cancer 2017 17:627
    Content type: Research article Published on:

  32. Breast cancer, comprising of several sub-phenotypes, is a leading cause of female cancer-related mortality in the UK and accounts for 15% of all cancer cases. Chemoresistant sub phenotypes of breast cancer rem...

    Authors: Layla Alnoumas, Lisa van den Driest, Zoe Apczynski, Alison Lannigan, Caroline H. Johnson, Nicholas J. W. Rattray and Zahra Rattray
    Citation: BMC Cancer 2022 22:874
    Content type: Research Published on:

  33. The gefitinib compassionate-use programme has enabled >39,000 patients worldwide to receive gefitinib ('Iressa', ZD1839) treatment. This paper reports the outcome of gefitinib treatment in Chinese patients who...

    Authors: Xin-Lin Mu, Long-Yun Li, Xiao-Tong Zhang, Shu-Lan Wang and Meng-Zhao Wang
    Citation: BMC Cancer 2004 4:51
    Content type: Research article Published on:

  35. Acapella plus active cycle of breathing technique (ACBT), external diaphragm pacemaker (EDP) plus ACBT have been shown to facilitate the recovery of functional capacity and lung function in patients suffering ...

    Authors: Xiaoxue Chen, Chuanzhen Li, Linjuan Zeng, Tiehua Rong, Peng Lin, Qinglin Wang, Zhixing Guo, Hao Long and Jiudi Zhong
    Citation: BMC Cancer 2023 23:282
    Content type: Research Published on:

  36. Compared with standard chemotherapy, epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are more effective in patients with advanced non-small-cell lung cancer (NSCLC) harboring EGFR mutat...

    Authors: Naoto Aiko, Tsuneo Shimokawa, Kazuhito Miyazaki, Yuki Misumi, Yoko Agemi, Mari Ishii, Yukiko Nakamura, Takeharu Yamanaka and Hiroaki Okamoto
    Citation: BMC Cancer 2018 18:1012
    Content type: Research article Published on:

  37. The study aimed to propose a modified N stage of esophageal cancer (EC) on the basis of the number of positive lymph node (PLN) and the number of negative lymph node (NLN) simultaneously.

    Authors: Jinling Zhang, Hongyan Li, Liangjian Zhou, Lianling Yu, Fengyuan Che and Xueyuan Heng
    Citation: BMC Cancer 2020 20:1200
    Content type: Research article Published on:

  38. The goal of this study was to determine the prognostic factors associated with an improved overall outcome after stereotactic body radiotherapy (SBRT) for primary lung cancer and metastatic lung tumors.

    Authors: Takaya Yamamoto, Keiichi Jingu, Yuko Shirata, Masashi Koto, Haruo Matsushita, Toshiyuki Sugawara, Masaki Kubozono, Rei Umezawa, Keiko Abe, Noriyuki Kadoya, Youjirou Ishikawa, Maiko Kozumi, Noriyoshi Takahashi, Ken Takeda and Yoshihiro Takai
    Citation: BMC Cancer 2014 14:464
    Content type: Research article Published on:

  39. Non-small cell lung cancers (NSCLC) are highly heterogeneous at the molecular level and comprise 75% of all lung tumors. We have previously shown that the receptor tyrosine kinase (RTK) MET frequently suffers ...

    Authors: Rajani Kanteti, Essam El-Hashani, Immanuel Dhanasingh, Maria Tretiakova, Aliya N Husain, Sherven Sharma, Jay Sharma, Everett E Vokes and Ravi Salgia
    Citation: BMC Cancer 2014 14:185
    Content type: Research article Published on:

  40. Protease activated receptor (PAR)-1 expression is increased in a variety of tumor cells. In preclinical models, tumor cell PAR-1 appeared to be involved in the regulation of lung tumor growth and metastasis; h...

    Authors: Cong Lin, Christof J. Majoor, Joris J. T. H. Roelofs, Martijn D. de Kruif, Hugo M. Horlings, Keren Borensztajn and C. Arnold Spek
    Citation: BMC Cancer 2017 17:113
    Content type: Research article Published on:

  41. Skeletal muscle indices have been associated with improved peri-operative outcomes after surgical resection of non-small-cell lung cancer (NSCLC). However, it is unclear if these indices can predict long term ...

    Authors: Yeshwanth Vedire, Lindsay Nitsche, Madeline Tiadjeri, Victor McCutcheon, Jack Hall, Joseph Barbi, Sai Yendamuri and Andrew D. Ray
    Citation: BMC Cancer 2023 23:778
    Content type: Research Published on:

  42. Amplifications of the transcription factor, SRY (sex determining region Y)-box 2 (SOX2), are common in non-small cell lung cancer (NSCLC). SOX2 signaling is important in maintaining the stem cell-like phenotype o...

    Authors: Johanna Samulin Erdem, Vidar Skaug, Per Bakke, Amund Gulsvik, Aage Haugen and Shanbeh Zienolddiny
    Citation: BMC Cancer 2016 16:28
    Content type: Research article Published on:

  43. Patients with lung adenocarcinoma (LUAD) may be more predisposed to coronavirus disease 2019 (COVID-19) and have a poorer prognosis. Currently, there is still a lack of effective anti-LUAD/COVID-19 drugs. Thus...

    Authors: Kun Zhang, Ke Wang, Chaoguo Zhang, Xiuli Teng, Dan Li and Mingwei Chen
    Citation: BMC Cancer 2022 22:687
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2022 22:822

  44. Hypoxia-induced genes are potential targets in cancer therapy. Responses to hypoxia have been extensively studied in vitro, however, they may differ in vivo due to the specific tumor microenvironment. In this stu...

    Authors: Katharina Leithner, Christoph Wohlkoenig, Elvira Stacher, Jörg Lindenmann, Nicole A Hofmann, Birgit Gallé, Christian Guelly, Franz Quehenberger, Philipp Stiegler, Freyja-Maria Smolle-Jüttner, Sjaak Philipsen, Helmut H Popper, Andelko Hrzenjak, Andrea Olschewski and Horst Olschewski
    Citation: BMC Cancer 2014 14:40
    Content type: Research article Published on:

  45. AURA study reported 61% objective response rate and progression-free survival of 9.6 months with osimertinib in patients with EGFR/T790M+ non-small cell lung cancer. Due to lack of real-world data, we proposed...

    Authors: Mariano Provencio, Josefa Terrasa, Pilar Garrido, Rosario García Campelo, Francisco Aparisi, Pilar Diz, David Aguiar, Carlos García-Giron, Julia Hidalgo, Carlos Aguado, Jorge García González, Emilio Esteban, Lorenzo Gómez-Aldavarí, Teresa Moran, Oscar Juan, Luís Enrique Chara…
    Citation: BMC Cancer 2021 21:230
    Content type: Research article Published on:

  47. The RAS family protooncogenes, including KRAS, NRAS and HRAS, encode proteins responsible for the regulation of growth, differentiation and survival of many cell types. The HRAS and KRAS oncogene mutations are we...

    Authors: Milena Pązik, Katarzyna Michalska, Marta Żebrowska-Nawrocka, Izabela Zawadzka, Mariusz Łochowski and Ewa Balcerczak
    Citation: BMC Cancer 2021 21:130
    Content type: Research article Published on:

  48. Metastatic colorectal cancer (mCRC) is a major cause of death of malignant tumor and the valuable prognostic biomarker for chemotherapy is crucial in decreasing mortality. Previous studies have proved the prog...

    Authors: Jinjia Chang, Guangyi Lin, Min Ye, Duo Tong, Jing Zhao, Dan Zhu, Qihe Yu, Wen Zhang and Wenhua Li
    Citation: BMC Cancer 2019 19:15
    Content type: Research article Published on:

  50. Vascular mimicry (VM) was associated with the prognosis of cancers. The aim of the study was to explore the association between VM and anticancer therapy response in patients with lung adenocarcinoma.

    Authors: Xuejun He, Jijun You, Haibing Ding, Zhisheng Zhang, Lin Cui, Xiaomei Shen, Xiaoxia Bian, Yanqing Liu and Jue Chen
    Citation: BMC Cancer 2021 21:132
    Content type: Research article Published on:

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